Ccs

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ccs 0.05 0.04 4.9e-04 0.03 0.04 0.02 0.04 1.8e-03 9.2e-05 2.8e-03 1.1e-04
2 NAcc alternative TSS XM_039092800.1 0.03 0.02 4.3e-03 0 0.02 0.01 0.01 1.8e-01 2.4e-03 1.1e-02 2.6e-02
3 NAcc alternative TSS NM_053425.1 0.03 0.02 4.0e-03 0 0.02 0.01 0.01 9.2e-02 1.9e-03 1.5e-02 1.6e-02
4 LHb alternative TSS NM_053425.1 0.22 0.12 1.4e-04 0.07 0.14 0.08 0.12 8.6e-03 3.9e-04 7.1e-03 7.7e-04
5 LHb alternative TSS XM_039092800.1 0.2 0.11 2.2e-04 0.06 0.13 0.06 0.09 1.5e-02 6.5e-04 1.6e-02 3.0e-03
6 Eye isoform ratio XM_039092800.1 0.67 0.27 1.0e-02 0.02 -0.02 0.01 -0.01 1.5e-01 9.5e-01 2.4e-01 5.3e-01
7 NAcc isoform ratio NM_053425.1 0.06 0.04 9.7e-05 0.04 0.04 0.04 0.04 5.4e-05 3.7e-05 1.4e-05 3.9e-05
8 NAcc gene expression Ccs 0.39 0.14 0.0e+00 0.39 0.39 0.39 0.39 1.2e-48 1.1e-47 7.0e-48 4.4e-48
9 IL gene expression Ccs 0.52 0.17 8.6e-10 0.23 0.13 0.25 0.07 2.4e-06 6.0e-04 1.3e-06 7.8e-03
10 Liver mRNA stability Ccs 0.04 0.03 1.2e-03 0.03 0.01 0.01 0.02 6.3e-04 8.2e-03 4.3e-02 4.5e-03
11 LHb gene expression Ccs 0.37 0.15 3.1e-07 0.21 0.24 0.24 0.26 1.1e-05 1.6e-06 2.0e-06 6.2e-07
12 OFC gene expression Ccs 0.65 0.16 3.2e-09 0.29 0.05 0.2 0.13 1.6e-07 2.3e-02 1.4e-05 5.1e-04
13 pVTA gene expression Ccs 0.49 0.15 0.0e+00 0.38 0.35 0.34 0.37 1.8e-17 7.8e-16 2.8e-15 9.4e-17
14 Liver intron excision ratio chr1_202114088_202114186 0.03 0.02 4.6e-03 0 -0 -0 -0 9.0e-02 5.9e-01 8.5e-01 4.4e-01
15 BLA gene expression Ccs 0.67 0.11 0.0e+00 0.43 0.46 0.45 0.44 5.4e-25 1.9e-27 4.2e-26 6.1e-26
16 PL gene expression Ccs 0.39 0.12 0.0e+00 0.44 0.45 0.45 0.45 7.2e-53 4.1e-55 1.4e-54 6.4e-55
17 Liver alternative polyA NM_053425.1 0.18 0.09 7.9e-15 0.1 0.12 0.11 0.11 1.1e-11 1.1e-12 4.4e-12 3.8e-12
18 Brain gene expression Ccs 0.28 0.05 0.0e+00 0.4 0.44 0.44 0.44 2.0e-39 5.2e-44 3.5e-45 2.9e-45
19 NAcc isoform ratio XM_039092800.1 0.05 0.04 2.0e-04 0.03 0.03 0.04 0.03 7.3e-05 9.0e-05 4.3e-05 6.8e-05
20 Liver gene expression Ccs 0.05 0.03 2.9e-05 0.03 0.03 0.02 0.02 5.4e-04 5.3e-04 2.5e-03 3.9e-03
21 Liver alternative polyA XM_039092800.1 0.19 0.09 3.1e-15 0.11 0.12 0.12 0.12 4.5e-12 2.7e-13 2.6e-13 1.0e-12
22 BLA intron excision ratio chr1_202126516_202126968 0.06 0.04 7.8e-03 0.01 0 0 0 5.2e-02 1.6e-01 2.2e-01 3.2e-01
23 BLA intron excision ratio chr1_202114437_202126456 0.06 0.04 6.8e-03 0.01 0.01 0 0 1.0e-01 1.1e-01 3.1e-01 3.3e-01
24 RMTg gene expression Ccs 0.37 0.15 1.7e-08 0.13 0.26 0.18 0.22 2.1e-04 1.6e-07 1.1e-05 1.5e-06
25 Eye isoform ratio NM_053425.1 0.56 0.27 7.8e-03 -0.02 -0.02 0.01 -0.02 7.6e-01 6.9e-01 2.1e-01 9.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.83.06.8-0.2-1.91.9-0.30.41.4-0.9-1.5-1.51.61.6-1.2-1.6-1.42.01.92.12.01.62.02.12.6-2.62.6-1.2
Area under the delay curve1.01.03.6-0.8-0.10.2-0.80.81.30.7-1.3-1.20.91.4-1.2-1.0-0.70.81.11.21.00.41.11.01.0-1.01.0-1.9
BMI with tail2.06.525.31.3-4.04.01.2-1.10.8-4.5-0.8-0.80.71.0-0.5-0.8-0.31.41.52.01.55.01.92.14.4-4.43.4-3.0
BMI without tail0.81.66.50.7-2.02.00.7-0.60.6-2.2-0.2-0.30.10.30.0-0.10.00.30.60.90.42.60.81.02.3-2.31.6-1.6
Body weight1.46.017.63.6-4.24.13.5-3.4-2.1-3.92.02.0-2.0-1.82.02.02.2-1.1-1.3-0.9-1.23.4-0.9-0.92.4-2.31.0-0.2
Weight adjusted by age1.71.94.22.0-1.61.61.9-1.9-1.7-2.11.41.5-1.3-1.31.41.41.4-0.9-1.2-1.1-1.11.4-1.1-1.00.4-0.5-0.30.7
Bone surface1.93.413.01.7-3.53.61.4-1.4-0.3-3.1-0.4-0.30.50.6-0.4-0.5-0.21.51.01.31.33.01.31.22.8-2.82.6-0.5
Bone volume1.52.66.30.6-2.42.50.4-0.30.4-2.0-1.1-0.91.21.2-0.9-1.2-0.91.91.51.71.72.21.71.62.4-2.42.5-0.6
Breakpoint value in progressive ratio session1.61.84.72.0-2.02.01.9-1.9-1.7-2.21.01.3-1.2-0.91.01.21.2-0.5-0.9-0.8-0.81.6-0.7-0.70.7-0.70.21.3
Number of licking bursts0.10.10.60.4-0.70.70.4-0.4-0.4-0.8-0.00.10.00.00.10.10.00.20.00.10.10.60.0-0.00.2-0.20.30.0
Context. condit. distance diff. score0.80.92.5-1.61.5-1.5-1.51.51.30.9-0.9-1.00.90.8-0.7-1.0-1.00.50.80.70.6-0.40.60.8-0.30.3-0.1-0.7
Locomotion velocity, session 10.20.30.60.10.4-0.40.3-0.3-0.40.30.40.4-0.4-0.60.30.80.6-0.7-0.7-0.6-0.7-0.2-0.7-0.8-0.40.4-0.8-0.5
Locomotion distance, session 10.91.23.60.1-1.31.30.1-0.10.7-1.2-0.8-0.70.80.7-1.0-0.3-0.60.80.81.00.91.90.90.91.8-1.81.4-1.8
Locomotion velocity, session 21.01.23.81.6-1.91.91.6-1.6-1.0-1.70.80.9-0.8-0.90.70.91.0-0.4-0.6-0.4-0.51.4-0.4-0.41.2-1.20.5-0.4
Locomotion distance, session 20.50.62.40.6-1.41.40.6-0.60.1-1.0-0.1-0.20.10.0-0.20.20.30.20.20.40.31.40.40.31.5-1.51.0-1.3
Locomotion velocity, session 30.40.51.1-0.5-0.20.2-0.50.50.70.3-0.7-0.70.70.6-1.0-0.6-0.60.60.70.80.80.30.80.80.8-0.80.7-1.1
Locomotion distance, session 30.00.00.5-0.10.1-0.1-0.10.1-0.00.7-0.1-0.10.1-0.0-0.3-0.1-0.10.00.10.10.1-0.50.10.10.1-0.10.0-0.4
Stereotopy head waving bouts, day 30.70.92.2-1.20.5-0.5-1.11.21.40.3-0.8-1.10.90.9-1.0-1.0-0.90.61.01.00.80.31.01.00.7-0.70.7-1.5
Stereotopy head waving duration, day 31.01.22.3-1.40.7-0.7-1.41.41.50.2-1.2-1.31.21.3-1.2-1.2-1.11.01.21.21.10.31.11.10.4-0.40.7-1.0
Locomotion velocity, session 70.91.01.7-0.8-0.10.1-0.80.91.3-0.4-1.0-1.10.91.0-1.2-1.2-1.10.81.11.11.00.71.11.31.0-1.11.1-0.9
Locomotion distance, session 70.10.10.6-0.1-0.20.2-0.10.10.8-0.4-0.0-0.2-0.0-0.1-0.1-0.1-0.1-0.20.20.20.00.60.20.30.7-0.80.3-0.7
Stereotopy head waving bouts, day 70.91.02.0-0.8-0.10.1-0.90.90.70.5-1.1-1.11.21.2-1.0-1.4-1.21.41.31.31.3-0.11.31.40.7-0.61.1-0.4
Stereotopy head waving duration, day 70.81.02.90.5-1.61.70.3-0.20.2-0.6-0.5-0.50.60.7-0.5-0.8-0.51.21.01.11.00.91.11.21.6-1.61.7-0.5
Locomotion velocity, session 80.80.91.61.2-0.80.81.3-1.2-1.0-1.01.11.1-1.1-1.21.11.21.2-1.1-1.0-0.9-1.00.7-0.9-0.90.2-0.2-0.50.0
Locomotion distance, session 80.30.40.9-0.80.3-0.3-0.70.70.7-0.3-0.8-0.80.80.7-0.7-0.5-0.60.60.60.70.60.70.60.60.4-0.40.4-0.9
Degree of sensitization distance0.30.30.9-0.1-0.40.4-0.10.20.9-0.6-0.3-0.40.20.3-0.1-0.3-0.10.20.40.50.30.90.50.50.9-0.90.6-0.7
Degree of sensitization stereotypy0.30.41.20.4-1.11.10.2-0.2-0.2-0.4-0.2-0.20.30.4-0.1-0.6-0.50.90.60.70.60.40.70.80.8-0.71.00.2
Conditioned locomotion2.02.44.01.9-1.00.91.8-1.8-1.7-1.12.01.7-1.9-2.01.81.71.8-1.7-1.7-1.6-1.70.0-1.6-1.6-0.40.4-1.01.4
Cocaine response after cond. corrected0.50.63.1-1.01.2-1.2-1.01.01.01.7-0.3-0.50.30.3-0.3-0.5-0.7-0.10.30.20.1-1.30.20.2-0.40.4-0.3-0.6
Cocaine response after cond. not corrected0.50.62.7-1.00.9-0.9-1.01.01.11.6-0.6-0.70.60.6-0.6-0.6-0.80.20.60.50.4-1.00.50.5-0.00.10.1-0.9
Cocaine response before conditioning0.20.31.10.5-1.01.10.5-0.5-0.5-0.8-0.30.00.20.4-0.2-0.00.20.70.20.30.50.90.30.20.6-0.60.7-0.2
Saline control response1.72.27.82.0-2.42.32.0-1.9-1.1-2.81.01.1-1.0-1.01.31.21.5-0.6-0.7-0.5-0.62.6-0.5-0.51.5-1.50.5-0.6
Bone: connectivity density1.92.98.60.9-2.92.90.7-0.70.6-2.4-0.7-0.70.80.9-0.8-0.9-0.81.41.31.51.42.71.51.62.9-2.92.6-0.7
Bone: cortical apparent density0.30.40.80.7-0.30.30.7-0.7-0.5-0.60.80.8-0.9-0.80.80.70.4-0.9-0.7-0.7-0.80.3-0.7-0.6-0.10.1-0.50.2
Bone: cortical area0.71.12.01.3-0.80.81.3-1.3-1.4-1.01.21.2-1.1-1.20.91.01.3-0.7-1.1-1.0-0.90.1-1.0-1.0-0.40.4-0.61.4
Bone: cortical porosity0.40.51.2-0.2-0.60.7-0.20.20.7-0.1-0.6-0.70.60.6-0.6-0.5-0.40.70.70.80.70.60.80.81.1-1.11.0-0.8
Bone: cortical porosity0.30.31.20.4-1.01.00.3-0.30.3-0.4-0.1-0.20.10.1-0.1-0.10.10.30.30.40.30.60.40.41.1-1.10.8-0.4
Bone: cortical thickness4.26.910.83.2-1.51.43.2-3.2-3.0-1.43.33.2-3.2-3.23.12.93.1-2.8-3.0-2.8-2.8-0.1-2.8-2.7-0.90.9-1.92.3
Bone: cortical thickness2.52.95.51.7-0.30.21.7-1.7-1.5-0.52.22.0-2.2-2.22.02.02.0-2.3-2.0-2.0-2.1-0.3-2.0-1.9-0.80.8-1.61.0
Bone: cortical tissue density0.40.51.00.9-0.40.40.8-0.8-0.6-0.60.90.9-1.0-0.91.00.80.5-1.0-0.8-0.8-0.90.3-0.8-0.7-0.10.1-0.50.2
Condit. Reinf. active minus inactive responses0.20.20.60.2-0.70.80.2-0.2-0.10.6-0.5-0.30.40.5-0.1-0.10.00.60.30.40.40.20.40.20.7-0.70.6-0.6
Condit. Reinf. active-inactive response ratio0.10.20.5-0.1-0.40.4-0.00.0-0.00.7-0.6-0.30.50.6-0.4-0.2-0.20.70.40.40.5-0.00.40.20.4-0.30.5-0.3
Condit. Reinf. active responses0.10.10.40.2-0.60.60.2-0.2-0.10.6-0.4-0.20.30.40.00.00.10.50.20.20.3-0.00.20.10.4-0.40.4-0.1
Condit. Reinf. inactive responses0.00.00.1-0.1-0.10.1-0.10.10.20.3-0.2-0.20.20.2-0.0-0.2-0.10.20.20.20.2-0.10.20.20.1-0.20.20.1
Incentive salience index mean0.20.20.90.3-0.91.00.3-0.3-0.00.4-0.5-0.20.40.4-0.2-0.00.10.60.30.40.40.30.40.20.8-0.80.7-0.6
Condit. Reinf. lever presses0.10.10.40.6-0.60.60.6-0.6-0.50.40.10.3-0.1-0.20.10.30.40.1-0.2-0.2-0.1-0.4-0.2-0.3-0.0-0.00.10.4
Condit. Reinf. active minus inactive responses1.11.33.1-0.9-0.10.2-0.90.90.7-0.4-1.5-1.31.51.5-1.3-1.3-1.41.81.31.41.50.91.31.30.6-0.61.2-0.9
Condit. Reinf. active-inactive response ratio1.21.33.2-1.20.5-0.4-1.21.20.6-0.2-1.6-1.31.61.6-1.5-1.4-1.31.81.31.31.40.51.21.1-0.10.10.8-0.3
Condit. Reinf. active responses1.41.93.3-0.5-0.91.0-0.60.61.0-0.9-1.5-1.31.51.6-1.3-1.3-1.41.81.61.71.71.61.61.61.6-1.51.8-1.5
Condit. Reinf. inactive responses1.01.24.20.1-1.41.40.1-0.01.0-0.9-0.5-0.70.50.6-0.5-0.7-0.60.61.01.10.91.41.11.22.1-2.01.6-1.6
Condit. Reinf. lever presses0.91.25.21.4-2.22.31.3-1.3-1.0-2.20.10.4-0.1-0.00.20.20.40.70.10.30.41.90.30.31.3-1.21.20.1
Condit. Reinf. lever reinforcers received1.11.63.2-0.2-1.21.3-0.20.30.6-1.3-1.2-1.01.31.3-1.0-1.1-1.11.71.31.51.51.81.41.41.6-1.51.7-1.2
Conditioned reinforcement - actives0.10.10.6-0.30.6-0.6-0.30.30.00.0-0.20.00.00.2-0.2-0.1-0.20.1-0.0-0.1-0.0-0.2-0.1-0.2-0.40.5-0.40.7
Conditioned reinforcement - inactives2.83.16.6-2.62.5-2.4-2.52.51.51.2-2.1-1.81.91.9-2.0-2.0-2.01.61.41.21.4-1.21.21.1-1.31.5-0.0-0.1
Conditioned locomotion2.83.412.9-2.93.6-3.6-2.82.71.41.5-1.4-1.51.41.3-1.5-1.5-1.50.70.80.50.7-1.70.40.4-2.22.2-1.10.4
Patch foraging indifference point 0 sec0.20.31.0-0.50.1-0.0-0.50.50.50.2-0.8-0.60.50.9-0.7-0.8-1.00.70.70.60.70.20.60.70.2-0.20.5-0.0
Patch foraging indifference point AUC2.42.812.72.2-2.01.92.1-2.1-1.8-3.61.71.7-1.6-1.61.81.21.5-1.1-1.2-1.0-1.22.4-1.0-0.90.6-0.6-0.10.9
Delay disc. indifference point, 0s delay1.11.26.1-1.30.5-0.5-1.11.21.70.3-0.9-1.31.10.9-0.7-1.0-0.80.41.01.10.90.71.01.01.1-0.90.7-2.5
Delay disc. indifference point, 16s delay2.02.03.7-1.40.4-0.4-1.41.41.21.9-1.9-1.61.61.9-1.8-1.7-1.51.61.51.51.7-1.01.51.30.3-0.41.1-1.3
Delay disc. indifference point, 2s delay0.30.31.0-0.70.2-0.2-0.60.60.60.3-0.8-0.70.80.8-0.6-0.4-0.40.60.60.70.60.10.60.50.1-0.00.4-1.0
Delay disc. indifference point, 24s delay0.30.32.9-0.10.4-0.5-0.00.00.21.7-0.00.1-0.6-0.10.20.10.3-0.7-0.3-0.4-0.4-1.1-0.4-0.5-0.20.1-0.5-0.1
Delay disc. indifference point, 4s delay0.50.52.7-0.70.1-0.2-0.70.71.20.2-0.7-0.80.50.8-0.5-0.6-0.50.20.70.70.50.50.70.70.9-0.80.6-1.6
Delay disc. indifference point, 8s delay0.40.42.4-0.5-0.00.0-0.50.51.00.5-0.7-0.70.40.7-0.7-0.4-0.30.20.60.70.40.40.60.50.9-0.80.5-1.5
Indifference point function ln k3.54.918.0-3.43.7-3.7-3.13.12.14.2-1.7-2.01.81.6-1.9-1.5-1.70.71.10.81.0-3.10.80.6-1.61.6-0.8-1.1
Indifference point function log k3.54.918.0-3.43.7-3.7-3.13.12.14.2-1.7-2.01.81.6-1.9-1.5-1.70.71.10.81.0-3.10.80.6-1.61.6-0.8-1.1
Patch foraging total patch changes 0 sec0.00.00.1-0.10.2-0.2-0.10.10.00.3-0.2-0.0-0.10.2-0.1-0.2-0.3-0.00.0-0.00.0-0.1-0.00.1-0.20.2-0.10.3
Patch foraging total patch changes 12 sec2.53.216.52.4-2.82.72.3-2.2-1.4-4.11.31.5-1.5-1.21.50.91.1-0.8-0.8-0.6-0.83.3-0.6-0.31.5-1.50.70.4
Patch foraging total patch changes 18 sec0.50.64.40.8-1.21.20.6-0.6-0.1-2.10.20.3-0.4-0.10.5-0.2-0.40.00.20.30.01.80.30.50.9-0.90.70.2
Patch foraging total patch changes 24 sec1.82.28.41.9-1.51.51.9-1.9-1.5-2.91.51.6-1.6-1.31.51.31.2-1.3-1.2-1.1-1.22.2-1.1-0.90.4-0.4-0.30.7
Patch foraging total patch changes 6 sec0.60.93.11.2-1.71.71.1-1.0-0.4-1.70.40.4-0.5-0.20.50.20.4-0.1-0.00.2-0.01.80.10.31.4-1.30.9-0.3
Patch foraging time to switch 0 sec1.01.66.71.0-2.52.60.9-0.80.1-0.5-0.6-0.40.40.6-0.6-0.30.11.10.91.01.01.11.10.92.2-2.32.0-0.7
Patch foraging water rate 0 sec1.72.712.0-1.93.5-3.5-1.71.70.21.6-0.2-0.20.10.1-0.1-0.2-1.0-0.6-0.4-0.7-0.6-1.9-0.8-0.6-3.03.0-2.11.3
Patch foraging water rate 12 sec2.94.420.9-2.94.5-4.6-2.62.51.32.8-0.4-0.80.60.3-0.5-0.4-1.0-0.9-0.2-0.5-0.6-2.8-0.6-0.6-3.13.0-2.40.2
Patch foraging water rate 18 sec1.01.36.1-1.82.4-2.5-1.61.61.01.6-0.6-0.80.60.5-0.7-0.4-0.6-0.10.10.00.0-1.2-0.1-0.1-1.41.4-1.1-0.4
Patch foraging water rate 24 sec1.62.310.5-1.93.2-3.2-1.71.60.42.0-0.3-0.40.2-0.0-0.1-0.0-0.9-0.6-0.4-0.5-0.6-2.1-0.6-0.6-2.42.4-1.90.6
Patch foraging water rate 6 sec1.52.29.3-1.63.0-3.1-1.41.30.42.20.2-0.1-0.2-0.30.10.3-0.4-1.1-0.7-0.9-0.9-2.3-0.9-0.9-2.42.4-2.10.5
Seeking ratio, delayed vs. immediate footshock0.60.71.7-0.5-0.40.4-0.50.50.80.3-1.1-0.91.01.0-0.9-0.6-0.50.90.91.01.00.30.90.90.8-1.01.0-1.3
Distance traveled before self-admin0.10.11.00.5-0.60.60.5-0.5-0.6-1.00.00.2-0.2-0.10.20.10.20.1-0.1-0.0-0.00.7-0.1-0.10.1-0.10.20.2
Distance traveled after self-admin0.10.11.50.3-0.40.40.3-0.3-0.5-1.2-0.10.10.0-0.00.00.10.00.3-0.00.00.10.80.0-0.0-0.10.10.20.1
Extensor digitorum longus weight3.614.132.25.7-5.35.25.5-5.5-3.9-4.44.04.0-3.9-3.83.93.94.0-2.8-3.0-2.6-2.83.0-2.6-2.51.9-1.9-0.11.3
Bone: elastic displacement1.31.53.5-0.11.6-1.6-0.0-0.0-0.50.81.20.8-1.1-1.21.00.90.7-1.6-1.3-1.4-1.4-1.4-1.4-1.4-1.81.8-1.91.0
Bone: elastic work2.22.85.11.6-0.40.31.7-1.7-1.5-1.42.21.9-2.1-2.22.11.91.9-2.3-2.0-1.9-2.00.4-1.9-1.8-0.80.7-1.50.8
Bone: endosteal estimation1.83.96.1-2.20.6-0.6-2.22.22.10.6-2.5-2.52.42.4-2.2-2.2-2.02.42.32.32.30.42.22.11.0-1.01.7-1.9
Bone: endosteal perimeter3.26.511.5-2.60.5-0.4-2.62.62.40.3-3.3-3.13.33.3-3.4-2.8-2.63.43.03.03.20.82.92.71.2-1.22.3-2.0
Epididymis fat weight1.74.08.4-2.92.3-2.2-2.92.92.31.3-2.3-2.32.12.1-2.1-2.2-2.91.61.91.81.6-0.61.71.8-0.50.50.6-0.5
Delta time in closed arm before/after self-admin0.60.51.80.6-0.10.00.7-0.6-0.20.21.10.8-1.1-1.11.10.70.4-1.4-0.9-0.8-1.1-0.2-0.8-0.50.1-0.3-0.6-0.1
Delta time in open arm before/after self-admin0.10.10.80.2-0.00.00.1-0.1-0.4-0.00.00.2-0.00.00.10.10.10.3-0.0-0.00.0-0.2-0.0-0.1-0.50.3-0.10.9
Diff in mean of infusions in LGA sessions0.60.62.41.0-0.50.50.9-1.0-1.0-0.50.91.0-1.0-0.60.90.70.3-0.7-0.8-0.8-0.7-0.0-0.8-0.6-0.20.3-0.51.6
Delay discount exponential model param0.70.72.70.70.1-0.10.6-0.6-1.1-0.61.21.0-0.7-1.21.00.80.5-0.6-0.9-1.0-0.8-0.4-0.9-0.8-1.00.9-0.91.7
Extinction: sum of active levers before priming1.81.86.22.0-2.52.51.8-1.8-1.3-2.30.60.9-0.8-0.60.70.80.7-0.1-0.4-0.3-0.22.1-0.2-0.21.6-1.40.90.5
Active lever presses in extinction session 62.32.24.92.0-1.11.11.9-1.9-2.2-0.91.71.8-1.6-1.71.61.61.5-1.1-1.5-1.6-1.4-0.0-1.5-1.5-0.60.7-0.91.7
Bone: final force1.01.64.71.9-2.12.11.9-1.9-1.3-2.21.11.1-1.0-1.01.01.11.4-0.4-0.8-0.6-0.61.6-0.6-0.60.9-0.90.30.3
Bone: final moment0.91.44.01.8-1.91.91.7-1.7-1.2-2.01.01.0-0.9-0.90.91.01.3-0.3-0.7-0.5-0.51.5-0.6-0.60.9-0.90.30.2
Food consumed during 24 hour testing period0.20.31.30.20.2-0.20.2-0.3-0.80.50.00.3-0.2-0.10.40.20.60.1-0.4-0.4-0.1-0.9-0.4-0.6-0.90.8-0.41.1
Glucose2.74.16.4-2.30.9-0.8-2.42.42.51.0-2.4-2.52.52.3-2.3-2.3-2.32.12.32.32.30.12.32.30.9-1.01.7-1.8
Heart weight1.72.55.0-2.21.8-1.7-2.22.22.21.8-1.4-1.81.61.3-1.4-1.9-2.21.01.51.41.3-1.11.41.5-0.10.10.5-0.7
Delay discount hyperbolic model param0.60.62.70.60.1-0.10.6-0.6-1.0-0.61.10.9-0.7-1.10.90.70.5-0.6-0.8-0.9-0.7-0.3-0.8-0.7-0.90.8-0.81.6
Intermittent access intake day 1-15 change0.40.41.6-0.21.0-0.9-0.20.2-0.60.40.30.3-0.1-0.30.2-0.00.0-0.1-0.4-0.5-0.3-1.0-0.5-0.5-1.21.2-0.91.0
Intermittent access intake escalation0.20.20.7-0.30.8-0.7-0.40.3-0.30.1-0.0-0.00.2-0.0-0.1-0.3-0.20.1-0.1-0.20.0-0.5-0.2-0.1-0.80.7-0.50.6
Intermittent access intake escalation 20.40.41.50.10.8-0.80.1-0.1-0.80.00.50.5-0.4-0.50.50.30.3-0.4-0.7-0.7-0.5-0.6-0.7-0.8-1.11.2-1.01.0
Intermitt. access day 1 inactive lever presses1.71.97.0-1.61.3-1.3-1.61.61.02.6-1.2-1.41.41.1-1.5-1.5-1.41.31.11.01.2-2.31.00.9-1.00.90.30.0
Intermitt. access day 15 inactive lever presses1.11.32.1-1.41.1-1.1-1.41.40.81.4-1.3-1.11.31.1-1.4-1.4-1.21.31.00.91.1-1.30.90.8-0.80.70.3-0.1
Intermitt. access escalation Index2.82.45.3-2.31.5-1.5-2.22.22.30.0-1.7-1.91.71.5-1.5-1.7-1.71.11.61.61.30.51.41.60.2-0.30.7-1.6
Intermittent access day 1 total infusions7.48.513.8-3.31.2-1.1-3.33.33.71.2-3.6-3.63.53.5-3.5-3.5-3.33.13.33.33.20.23.23.11.5-1.42.4-2.2
Intermittent access day 15 total infusions4.95.510.0-3.22.2-2.1-3.23.12.61.3-2.9-2.82.82.7-2.8-2.9-2.82.42.42.32.4-0.72.22.1-0.10.21.0-0.9
Intermittent access terminal intake (last 3 days)4.34.77.5-2.71.6-1.5-2.72.72.41.3-2.7-2.62.62.6-2.6-2.7-2.72.42.32.22.3-0.62.22.10.3-0.11.2-0.8
Intermittent access total infusions5.15.78.9-2.71.0-0.9-2.72.72.90.9-3.0-2.92.92.9-2.9-2.9-2.82.72.72.72.70.12.62.61.1-1.01.9-1.5
Intermittent access day 1 locomotion5.76.010.6-2.50.6-0.5-2.62.63.31.5-2.9-2.92.82.8-2.9-2.8-2.62.52.82.82.70.12.82.71.6-1.52.2-2.5
Intermittent access day 15 total locomotion3.43.66.2-2.51.6-1.5-2.52.52.10.6-2.3-2.32.42.2-2.4-2.3-2.32.02.02.02.0-0.21.91.90.1-0.01.0-0.9
Intermittent access total locomotion7.58.513.4-3.31.3-1.2-3.43.43.40.4-3.6-3.53.63.5-3.7-3.6-3.43.23.33.33.30.63.23.11.1-1.02.3-2.2
Intermittent access standard deviation0.30.31.2-0.81.1-1.1-0.80.70.30.5-0.3-0.40.40.2-0.3-0.5-0.50.20.10.10.1-0.60.10.0-0.70.7-0.40.2
Left kidney weight0.20.73.0-1.11.7-1.7-1.01.00.00.4-0.3-0.30.30.2-0.2-0.4-0.60.10.0-0.10.0-0.8-0.2-0.1-1.61.6-0.91.0
Right kidney weight0.30.84.4-0.21.2-1.1-0.20.1-1.00.20.20.5-0.2-0.30.20.2-0.6-0.1-0.5-0.6-0.3-1.0-0.7-0.6-2.02.0-1.12.1
Cocaine induced anxiety0.10.11.00.20.1-0.10.2-0.2-0.40.30.30.3-0.3-0.30.30.20.2-0.2-0.3-0.4-0.3-0.5-0.3-0.4-0.40.7-0.31.0
Post-drug Anxiety1.51.63.81.6-0.80.81.5-1.5-1.8-0.01.41.5-1.4-1.31.41.31.3-1.0-1.3-1.3-1.2-0.7-1.3-1.4-0.70.9-0.82.0
Baseline Anxiety1.71.83.51.9-1.31.31.9-1.9-1.7-1.01.61.7-1.6-1.51.51.51.5-1.1-1.4-1.3-1.20.6-1.3-1.2-0.10.0-0.60.9
Tail length1.75.28.52.1-0.20.12.2-2.2-2.5-0.42.72.7-2.7-2.62.52.92.4-2.7-2.8-2.8-2.8-0.5-2.7-2.7-1.51.6-2.41.9
Length with tail2.17.612.93.6-2.12.03.6-3.6-3.4-1.23.43.3-3.2-3.23.13.33.0-2.7-3.0-2.9-2.80.1-2.8-2.9-0.60.6-1.62.2
Length without tail1.43.06.72.6-2.32.32.6-2.6-2.2-1.91.91.9-1.7-1.81.71.81.7-1.1-1.5-1.3-1.31.2-1.3-1.30.6-0.6-0.20.7
Times rat made contact with spout0.20.31.00.5-1.01.00.5-0.40.1-0.7-0.1-0.10.00.10.00.10.20.10.20.30.20.80.30.21.0-1.00.7-0.8
Lifetime Intake4.75.38.8-2.50.9-0.8-2.62.63.00.7-2.8-2.82.82.7-2.7-2.8-2.72.52.72.72.60.32.62.51.3-1.21.9-1.6
Liver weight, left0.10.21.1-0.20.6-0.6-0.20.2-0.1-1.00.30.2-0.3-0.40.20.00.3-0.5-0.3-0.3-0.30.3-0.3-0.2-0.40.4-0.5-0.1
Liver weight, right0.10.10.8-0.20.4-0.5-0.10.10.0-0.90.30.1-0.3-0.40.20.30.3-0.6-0.3-0.3-0.50.6-0.3-0.3-0.10.1-0.5-0.5
Locomotor activity0.61.04.6-1.12.1-2.1-0.90.90.31.40.10.0-0.1-0.10.10.1-0.5-0.9-0.5-0.6-0.7-1.1-0.7-0.6-1.41.5-1.5-0.3
Locomotor testing distance0.81.36.3-1.42.4-2.5-1.21.10.71.70.0-0.10.0-0.00.00.2-0.5-1.1-0.5-0.6-0.7-1.2-0.7-0.6-1.41.5-1.6-0.7
Locomotor testing rearing0.71.13.1-1.81.7-1.7-1.61.61.60.8-0.9-1.10.90.9-0.7-0.8-1.00.10.70.70.4-0.10.60.7-0.10.2-0.2-1.4
Locomotion in novel chamber2.32.86.5-2.52.4-2.4-2.52.41.41.0-2.0-1.82.01.9-2.0-1.8-1.81.51.31.21.5-0.61.11.0-0.91.1-0.1-0.6
Locomotion in novel chamber post-restriction1.31.63.7-1.91.9-1.9-1.81.81.31.8-1.0-1.21.31.1-1.2-1.2-1.30.80.90.80.8-1.40.70.7-0.80.8-0.2-0.3
Fecal boli incidents, locomotor time 10.10.11.30.3-0.10.20.1-0.1-0.3-0.10.30.2-0.0-0.30.1-0.5-0.40.30.1-0.00.2-0.50.10.1-0.50.40.11.1
Change in fecal boli incidents, locomotor task0.30.32.4-0.2-0.20.2-0.20.20.60.1-0.4-0.40.40.5-0.6-0.20.00.00.30.40.30.60.30.41.2-0.90.4-1.6
Time >=10cm from walls, locomotor time 13.43.56.2-1.5-0.10.2-1.61.61.6-0.4-2.4-2.22.32.5-2.5-2.1-2.02.52.22.22.31.12.22.01.5-1.21.9-1.2
Bouts of movement, locomotor time 10.50.51.41.2-1.21.21.1-1.1-1.10.10.70.7-0.6-0.60.60.50.6-0.1-0.5-0.5-0.2-0.5-0.4-0.50.1-0.20.10.9
Total resting periods, locomotor time 10.20.31.20.9-1.11.10.8-0.8-0.8-0.30.40.4-0.3-0.30.20.10.20.2-0.1-0.10.1-0.1-0.1-0.20.2-0.30.40.7
Rest time, locomotor task time 10.91.04.2-1.21.6-1.6-1.11.00.22.1-0.7-0.50.60.5-0.6-0.5-0.40.40.20.10.4-2.00.0-0.1-1.51.3-0.60.2
Distance moved, locomotor task time 10.80.84.40.0-0.90.9-0.00.00.6-1.9-0.5-0.60.40.6-0.4-0.5-0.30.60.70.80.52.10.80.91.4-1.21.1-1.2
Vertical activity count, locomotor time 10.30.31.0-0.91.0-1.0-0.90.90.80.3-0.4-0.50.20.5-0.4-0.7-0.70.10.30.30.2-0.10.30.4-0.20.3-0.2-0.3
Time >=10cm from walls, locomotor time 20.20.20.9-0.2-0.00.1-0.20.2-0.1-0.8-0.6-0.40.40.6-0.6-0.3-0.40.70.40.40.50.90.40.30.4-0.20.30.2
Bouts of movement, locomotor time 20.20.20.90.8-0.90.90.7-0.7-0.40.30.40.3-0.3-0.30.40.30.3-0.2-0.2-0.1-0.2-0.2-0.1-0.10.4-0.30.30.3
Total resting periods, locomotor time 20.10.10.60.5-0.80.80.4-0.4-0.10.50.10.00.0-0.00.0-0.00.00.10.10.10.1-0.40.10.20.4-0.40.40.2
Rest time, locomotor task time 21.31.55.7-1.71.7-1.7-1.71.71.22.4-1.1-1.21.01.0-1.2-1.1-1.00.60.80.70.7-2.00.70.7-0.90.6-0.1-0.5
Distance moved, locomotor task time 20.80.94.11.2-1.11.11.2-1.2-1.2-2.00.70.9-0.9-0.60.80.81.0-0.5-0.8-0.6-0.61.7-0.6-0.60.5-0.2-0.10.2
Vertical activity count, locomotor time 21.31.52.70.70.6-0.60.8-0.8-1.10.11.41.3-1.6-1.31.41.21.2-1.6-1.5-1.5-1.5-0.4-1.6-1.5-0.91.1-1.60.7
Light reinforcement 10.10.10.5-0.50.7-0.7-0.50.50.3-0.0-0.1-0.20.10.2-0.1-0.2-0.4-0.20.1-0.00.0-0.0-0.00.0-0.30.4-0.30.0
Light reinforcement 20.71.02.7-1.11.3-1.2-1.11.10.11.6-0.9-0.71.20.9-0.9-0.8-1.11.00.50.40.9-1.60.40.2-1.41.3-0.20.8
Bone: marrow area1.84.06.2-2.20.7-0.6-2.22.22.20.7-2.5-2.52.52.4-2.2-2.2-2.12.42.32.32.30.42.22.11.1-1.11.7-1.9
Bone: maximum diameter0.10.10.50.3-0.30.30.3-0.3-0.7-0.3-0.00.10.10.0-0.40.00.20.5-0.1-0.10.2-0.1-0.1-0.2-0.40.40.00.7
Bone: maximum force1.32.28.61.7-2.92.91.6-1.5-0.8-2.90.10.2-0.00.00.00.20.40.80.30.60.62.80.50.52.1-2.01.7-0.7
Bone: maximum moment1.11.97.41.5-2.72.71.4-1.4-0.7-2.70.00.20.00.10.00.20.40.80.30.60.62.60.50.42.0-1.91.6-0.8
Mean time between licks in bursts0.30.51.00.7-0.40.40.8-0.8-0.40.10.70.7-0.7-0.70.71.01.0-0.9-0.8-0.7-0.80.3-0.7-0.80.3-0.3-0.4-0.8
Mean num. licks in bursts0.10.20.6-0.50.2-0.3-0.50.50.80.5-0.3-0.50.30.3-0.4-0.4-0.20.10.40.40.3-0.20.40.40.4-0.40.3-0.6
Cd content in liver0.60.72.3-1.01.5-1.5-1.01.00.01.3-0.5-0.40.40.5-0.5-0.5-0.70.30.20.00.2-1.50.00.0-1.31.3-0.60.7
Co content in liver1.11.33.9-0.61.9-2.0-0.50.40.11.70.70.5-0.8-0.80.90.80.9-1.5-1.0-1.1-1.3-1.6-1.1-1.0-1.41.4-1.70.1
Cu content in liver0.30.32.30.5-0.80.80.5-0.5-0.2-1.50.20.2-0.2-0.20.10.10.50.1-0.00.1-0.01.30.10.20.6-0.70.4-0.4
Fe content in liver0.20.31.30.5-0.10.10.5-0.5-0.5-1.10.50.5-0.4-0.50.60.30.4-0.4-0.4-0.4-0.40.7-0.5-0.4-0.40.3-0.30.9
K content in liver0.90.93.90.9-1.92.00.8-0.8-0.0-0.9-0.1-0.10.20.1-0.30.10.30.60.50.60.61.20.60.61.8-1.81.4-1.0
Mg content in liver2.82.85.9-0.5-1.41.4-0.60.71.5-0.9-1.5-1.61.71.6-1.6-1.4-1.21.91.92.01.91.72.01.92.4-2.42.4-2.2
Mn content in liver0.91.04.01.7-2.02.01.6-1.6-1.3-1.20.80.9-0.7-0.60.70.60.2-0.1-0.4-0.3-0.21.0-0.3-0.30.8-0.70.60.9
Na content in liver0.91.02.21.1-0.50.51.2-1.2-1.5-1.50.91.2-0.9-0.90.81.11.0-0.6-1.1-1.0-0.90.8-1.0-1.1-0.70.7-0.71.1
Rb content in liver2.12.64.7-1.80.6-0.6-1.81.92.20.4-1.7-1.91.81.7-1.7-1.8-1.51.51.81.81.60.31.81.91.2-1.21.4-2.0
Se content in liver0.81.02.1-0.3-0.70.7-0.40.40.4-1.4-1.0-0.91.11.1-1.0-1.2-1.01.41.11.21.31.41.21.20.7-0.81.30.1
Sr content in liver2.62.44.12.0-1.11.02.0-2.0-2.0-0.61.61.9-1.8-1.61.81.61.8-1.4-1.7-1.6-1.5-0.1-1.6-1.6-0.60.6-1.01.8
Zn content in liver0.40.51.81.1-1.31.31.1-1.0-0.7-0.50.40.6-0.6-0.40.60.50.8-0.2-0.3-0.3-0.20.3-0.2-0.20.6-0.70.40.1
Bone: minimum diameter2.34.36.3-1.90.1-0.0-2.02.02.30.1-2.5-2.52.42.5-2.3-2.5-2.12.52.52.52.50.82.52.51.6-1.62.2-1.8
Time in familiar zone, hab. session 10.70.71.5-0.80.1-0.0-0.80.80.80.6-1.1-0.91.01.1-1.2-0.9-0.81.00.90.91.10.00.90.80.5-0.50.8-0.9
Time in novel zone, hab. session 10.50.51.0-0.10.8-0.80.0-0.0-0.20.50.70.5-0.7-0.80.90.60.7-1.0-0.7-0.7-0.9-0.6-0.8-0.7-0.70.7-1.00.3
Total zone transitions, hab. session 10.30.41.50.9-1.21.20.9-0.9-0.5-1.10.30.4-0.3-0.30.30.70.4-0.1-0.2-0.1-0.21.2-0.2-0.20.7-0.70.3-0.1
Total locomotion distance, hab. session 10.20.30.6-0.80.5-0.5-0.80.80.70.8-0.7-0.70.70.7-0.6-0.5-0.60.60.60.50.5-0.40.50.4-0.0-0.00.2-0.4
Locomotion velocity, hab. session 10.10.10.2-0.30.1-0.0-0.30.30.40.4-0.4-0.40.40.3-0.3-0.2-0.30.30.30.30.3-0.10.30.20.1-0.20.2-0.3
Time in familiar zone, hab. session 20.60.61.60.40.3-0.40.4-0.4-0.30.71.00.7-1.0-1.01.00.81.0-1.3-0.9-0.9-1.0-0.8-0.9-0.9-0.30.3-0.9-0.3
Time in novel zone, hab. session 20.70.71.3-0.3-0.60.7-0.30.40.6-0.7-0.9-0.80.90.9-0.9-0.8-0.91.11.01.01.11.01.01.00.8-0.81.1-0.3
Total zone transitions, hab. session 22.73.59.70.2-2.32.30.1-0.01.1-2.2-1.2-1.31.21.2-1.0-1.1-1.31.51.61.91.63.11.81.93.1-3.02.6-2.6
Total locomotion distance, hab. session 21.31.73.8-0.8-0.60.6-0.80.81.4-0.5-1.3-1.41.31.3-1.0-1.2-1.41.31.51.61.31.31.51.61.7-1.61.6-2.0
Locomotion velocity, hab. session 21.41.93.5-1.0-0.40.5-1.01.01.4-0.4-1.5-1.61.51.5-1.2-1.3-1.61.51.61.71.51.21.61.61.6-1.51.6-1.9
Novel to familiar place preference ratio0.50.51.80.6-1.31.30.5-0.5-0.5-1.2-0.3-0.10.40.4-0.3-0.4-0.20.90.50.60.71.00.60.60.7-0.71.00.6
Novelty place preference0.50.51.20.2-0.91.00.1-0.1-0.2-0.9-0.6-0.40.70.7-0.6-0.7-0.51.10.70.70.90.80.80.80.6-0.61.00.4
Time in novel zone, NPP test0.40.41.00.1-0.80.90.00.0-0.1-0.7-0.6-0.40.70.6-0.5-0.7-0.51.00.70.70.90.70.70.80.6-0.61.00.3
Total zone transitions, NPP test0.91.36.01.1-2.02.01.1-1.1-0.4-2.2-0.00.2-0.0-0.10.20.50.30.30.10.30.22.40.30.21.7-1.61.1-1.2
Total locomotion distance, NPP test0.20.21.1-0.2-0.30.3-0.10.20.4-0.2-0.5-0.40.50.5-0.2-0.1-0.30.50.40.50.40.70.50.40.7-0.60.5-1.1
Locomotion velocity, NPP test0.10.20.8-0.1-0.40.4-0.00.00.2-0.4-0.4-0.30.40.4-0.2-0.0-0.30.40.30.40.40.80.40.30.5-0.50.5-0.9
Intraocular pressure0.71.05.1-0.41.4-1.4-0.60.5-0.31.40.20.2-0.2-0.10.1-0.3-1.0-0.2-0.2-0.5-0.2-2.1-0.4-0.3-1.81.9-1.02.3
Delta distance traveled before/after self-admin0.00.00.00.00.1-0.10.0-0.0-0.1-0.20.20.1-0.2-0.1-0.00.1-0.1-0.1-0.1-0.1-0.20.2-0.1-0.1-0.10.1-0.20.2
Delta ambulatory time before/after self-admin0.10.10.10.20.1-0.10.1-0.1-0.1-0.30.30.2-0.3-0.30.20.20.1-0.4-0.3-0.3-0.30.3-0.3-0.2-0.0-0.0-0.3-0.1
Parametrial fat weight1.93.87.2-2.61.6-1.6-2.72.72.6-0.3-2.0-2.32.22.0-2.1-2.6-2.51.72.12.11.90.32.02.20.2-0.21.1-0.8
Pavlov. Cond. lever latency0.00.10.3-0.30.5-0.5-0.30.30.00.1-0.1-0.10.00.20.1-0.0-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.50.4-0.30.1
Pavlov. Cond. magazine entry latency0.81.12.0-0.3-0.80.8-0.40.50.7-0.0-1.1-1.01.11.1-1.2-1.1-1.21.31.21.21.30.61.31.21.2-1.11.4-1.0
Pavlov. Cond. change in total contacts0.40.51.5-0.3-0.30.4-0.30.30.00.1-0.9-0.60.90.9-1.0-0.8-0.91.20.80.81.00.20.80.70.3-0.20.80.1
Pavlov. Cond. index score0.00.00.20.1-0.30.30.1-0.1-0.10.3-0.2-0.10.30.1-0.4-0.2-0.30.40.20.20.3-0.20.20.10.1-0.00.30.1
Pavlov. Cond. latency score0.10.10.2-0.1-0.20.2-0.10.10.20.4-0.3-0.20.40.2-0.5-0.3-0.40.40.40.30.4-0.20.30.30.3-0.20.4-0.2
Pavlov. Cond. lever contacts0.00.00.4-0.0-0.00.1-0.00.00.20.6-0.0-0.00.1-0.1-0.1-0.1-0.10.00.10.00.1-0.40.10.00.1-0.10.1-0.1
Pavlov. Cond. magazine entry number0.10.10.4-0.40.3-0.4-0.30.30.7-0.1-0.0-0.2-0.10.10.10.00.1-0.30.00.0-0.10.30.00.10.2-0.2-0.1-0.5
Pavlov. Cond. intertrial magazine entries0.10.20.7-0.20.7-0.7-0.20.2-0.20.10.10.2-0.1-0.00.4-0.0-0.1-0.1-0.2-0.3-0.2-0.3-0.3-0.2-0.70.8-0.60.8
Pavlov. Cond. lever-magazine prob. diff.0.00.10.30.3-0.50.50.2-0.2-0.20.1-0.10.00.20.1-0.3-0.1-0.20.40.20.20.30.00.20.10.2-0.20.30.1
Pavlov. Cond. response bias0.00.00.30.2-0.20.20.2-0.2-0.40.5-0.00.10.1-0.0-0.2-0.0-0.20.30.0-0.00.2-0.50.0-0.1-0.10.20.10.3
Pavlov. Cond. lever latency0.20.31.2-0.71.0-1.0-0.60.60.71.1-0.2-0.20.00.2-0.1-0.0-0.3-0.4-0.0-0.1-0.2-0.7-0.1-0.1-0.30.3-0.5-0.7
Pavlov. Cond. magazine entry latency1.31.57.21.7-2.72.71.6-1.6-0.8-1.60.20.5-0.3-0.20.30.50.70.4-0.00.20.21.80.20.21.7-1.81.3-0.3
Pavlov. Cond. change in total contacts0.81.24.91.1-2.12.20.9-0.9-0.9-1.7-0.3-0.10.50.4-0.5-0.30.01.40.60.71.01.50.70.61.1-1.21.50.4
Pavlov. Cond. index score0.91.15.11.5-2.22.31.4-1.3-1.0-1.70.10.4-0.0-0.10.10.30.70.70.00.20.41.50.20.11.1-1.21.10.4
Pavlov. Cond. latency score0.70.94.11.3-2.02.01.2-1.2-1.0-1.50.10.4-0.0-0.10.10.30.70.60.00.20.41.30.20.10.9-1.01.00.4
Pavlov. Cond. lever contacts0.20.31.10.8-0.80.80.8-0.8-1.0-1.00.40.6-0.3-0.40.30.40.70.1-0.4-0.3-0.10.5-0.3-0.3-0.10.10.01.0
Pavlov. Cond. magazine entry number2.12.611.8-2.43.4-3.4-2.32.21.42.1-0.5-0.90.50.4-0.7-0.8-1.1-0.40.2-0.0-0.2-2.1-0.10.0-2.02.0-1.50.0
Pavlov. Cond. intertrial magazine entries0.50.62.0-1.21.4-1.4-1.21.20.80.9-0.6-0.70.50.6-0.6-0.6-1.00.30.40.30.3-0.80.30.3-0.70.8-0.30.1
Pavlov. Cond. lever-magazine prob. diff.1.01.36.01.6-2.42.41.5-1.5-1.1-1.80.30.5-0.1-0.20.30.40.80.6-0.00.10.31.50.20.11.2-1.31.10.4
Pavlov. Cond. response bias0.60.93.51.4-1.81.91.3-1.3-1.0-1.60.30.6-0.2-0.30.30.30.70.4-0.1-0.00.21.40.0-0.00.8-0.80.80.6
Time in closed arm before self-admin0.20.20.7-0.3-0.20.2-0.30.30.20.0-0.7-0.50.70.7-0.7-0.3-0.60.90.60.60.70.10.60.30.1-0.20.6-0.3
Time in closed arm after self-admin0.10.10.5-0.0-0.00.0-0.00.00.20.7-0.0-0.10.0-0.10.0-0.0-0.6-0.10.00.00.0-0.60.00.0-0.0-0.10.0-0.2
Time in open arm before self-admin0.10.10.5-0.40.6-0.7-0.30.30.70.20.1-0.1-0.3-0.20.20.10.3-0.7-0.2-0.2-0.40.0-0.2-0.10.3-0.1-0.4-0.7
Time in open arm after self-admin0.20.20.6-0.10.7-0.7-0.10.1-0.10.60.30.3-0.4-0.30.40.40.5-0.5-0.4-0.5-0.6-0.8-0.5-0.5-0.70.6-0.70.7
Bone: periosteal estimation0.10.20.8-0.3-0.10.1-0.40.40.2-0.4-0.6-0.60.60.6-0.5-0.6-0.30.90.60.60.70.30.60.50.2-0.20.5-0.0
Bone: periosteal perimeter0.30.51.4-0.1-0.70.7-0.20.20.2-0.8-0.8-0.60.80.8-0.9-0.7-0.41.20.80.91.00.80.80.70.7-0.71.0-0.2
Bone: post-yield work6.79.117.4-1.1-2.22.4-1.31.42.1-1.3-3.3-3.03.33.4-3.2-3.0-2.94.13.53.73.82.63.73.53.4-3.44.2-2.5
Progressive ratio test 1 active lever presses1.61.73.2-1.81.3-1.2-1.81.81.71.2-1.6-1.51.51.6-1.5-1.5-1.51.21.31.21.2-0.51.21.20.0-0.00.5-0.4
Progressive ratio test 1 breakpoint1.31.32.6-1.61.2-1.2-1.61.61.51.3-1.4-1.31.21.4-1.3-1.3-1.31.01.11.01.0-0.71.00.9-0.20.10.3-0.3
Progressive ratio test 1 inactive lever presses1.01.11.8-1.30.7-0.7-1.31.31.31.1-1.3-1.21.21.2-1.1-1.2-1.10.91.11.01.0-0.51.01.00.3-0.20.6-1.1
Progressive ratio test 2 active lever presses2.62.85.0-2.21.5-1.4-2.22.21.90.6-2.2-2.02.02.1-2.1-2.0-2.11.81.81.71.7-0.11.61.60.00.00.8-1.0
Progressive ratio test 2 breakpoint2.32.65.5-2.32.0-2.0-2.32.31.81.0-2.0-1.81.81.9-1.9-1.8-1.91.51.51.31.4-0.61.31.2-0.50.60.3-0.7
Progressive ratio test 2 inactive lever presses6.06.912.5-3.52.4-2.3-3.53.53.10.9-3.4-3.13.13.2-3.1-3.1-3.12.62.72.62.6-0.32.52.4-0.10.21.2-1.8
Incentive Sensitization - Responses0.60.61.2-0.70.1-0.1-0.70.70.7-0.3-1.0-0.90.90.9-1.0-1.0-1.01.10.90.90.90.60.90.80.5-0.40.7-0.6
Incentive Sensitization - Breakpoint0.60.61.3-0.80.3-0.3-0.90.80.7-0.2-1.1-0.91.00.9-1.1-1.0-1.01.10.90.91.00.50.90.80.4-0.20.6-0.6
Sum of active levers in priming session hrs 5-62.72.67.51.8-0.50.51.7-1.8-2.7-1.51.62.0-1.6-1.41.61.51.0-1.0-1.8-1.8-1.50.2-1.8-1.7-1.51.5-1.42.7
Progressive ratio1.82.06.10.6-2.32.30.5-0.40.6-2.1-0.5-0.70.80.7-0.6-0.6-0.51.21.11.41.32.11.31.42.4-2.52.2-0.7
Food seeking constrained by brief footshock0.40.40.90.7-0.40.40.7-0.7-0.6-0.70.90.7-0.9-0.80.70.90.8-1.0-0.7-0.6-0.80.3-0.6-0.5-0.1-0.1-0.4-0.4
Seeking ratio, punishment vs. effort1.31.64.4-0.62.1-2.1-0.50.4-0.41.90.50.5-0.8-0.70.50.80.6-1.4-1.1-1.2-1.3-1.8-1.2-1.2-2.01.9-1.9-0.0
Retroperitoneal fat weight2.99.621.1-4.63.8-3.8-4.54.53.61.9-3.4-3.53.53.3-3.4-3.7-4.02.52.92.72.7-1.02.52.6-1.01.00.7-1.0
Reaction time number correct0.71.01.51.0-0.20.11.0-1.0-1.20.21.11.1-1.2-1.11.21.10.6-1.1-1.1-1.2-1.1-0.5-1.1-1.1-0.80.8-1.01.0
Reaction time mean minus median1.01.34.81.9-2.22.21.8-1.8-1.5-1.50.71.0-0.7-0.70.60.70.5-0.1-0.5-0.4-0.31.0-0.4-0.30.8-0.80.61.1
Reaction time mean minus median AUC1.11.43.31.8-1.31.31.7-1.7-1.6-1.31.41.4-1.2-1.31.21.20.8-0.9-1.1-1.1-1.00.3-1.0-0.9-0.10.1-0.41.5
Reaction time num false alarms0.70.92.50.10.9-1.00.2-0.2-0.11.00.90.8-1.1-1.01.11.00.9-1.6-1.1-1.2-1.3-0.9-1.2-1.1-1.01.0-1.40.4
Reaction time num false alarms AUC0.91.33.10.80.2-0.30.9-0.9-0.60.91.31.2-1.4-1.31.51.41.2-1.8-1.4-1.4-1.5-0.7-1.4-1.3-0.70.6-1.30.5
Reaction time trials correct on left0.71.01.51.0-0.20.11.0-1.0-1.20.21.11.1-1.2-1.11.21.10.6-1.1-1.1-1.2-1.1-0.5-1.1-1.1-0.80.8-1.01.0
Reaction time trials on left0.81.21.81.1-0.20.21.1-1.2-1.30.21.31.3-1.3-1.21.41.20.7-1.2-1.3-1.3-1.2-0.5-1.3-1.2-0.90.9-1.11.1
Reaction time mean0.00.00.10.0-0.20.20.0-0.0-0.10.0-0.4-0.10.10.3-0.4-0.1-0.20.40.20.20.2-0.20.20.10.0-0.00.20.2
Reaction time mean AUC0.10.10.3-0.1-0.20.2-0.10.10.0-0.0-0.5-0.20.30.4-0.6-0.2-0.40.60.30.30.4-0.00.30.30.1-0.10.30.1
Median of all reaction times0.10.20.5-0.50.2-0.2-0.50.50.30.4-0.7-0.50.50.6-0.7-0.3-0.50.60.50.40.5-0.30.40.30.1-0.00.3-0.3
Reaction time omissions0.91.22.91.7-1.31.31.6-1.6-1.3-0.41.21.3-1.3-1.21.21.20.8-1.0-1.0-1.0-0.90.0-0.9-0.90.1-0.1-0.31.0
Reaction time false alarm rate0.30.41.20.00.6-0.60.1-0.10.11.10.60.5-0.7-0.70.70.70.8-1.1-0.7-0.7-0.8-0.8-0.7-0.7-0.50.4-0.80.1
Reaction time premature initiation rate1.52.03.81.9-1.31.31.9-1.9-1.4-0.71.71.7-1.6-1.71.61.81.5-1.7-1.5-1.4-1.50.8-1.4-1.30.5-0.4-0.70.1
Reaction time premature initiations3.04.27.42.6-1.61.52.7-2.7-2.3-0.72.52.5-2.4-2.42.42.62.1-2.4-2.3-2.2-2.20.5-2.2-2.1-0.00.1-1.30.8
Std. dev. reaction times0.20.31.21.0-1.11.10.9-0.9-0.8-0.50.30.6-0.4-0.30.20.40.10.0-0.3-0.2-0.20.1-0.2-0.20.3-0.20.30.9
Reaction time trials completed0.81.21.81.1-0.20.21.1-1.2-1.30.21.31.3-1.3-1.21.41.20.7-1.2-1.3-1.3-1.2-0.5-1.3-1.2-0.90.9-1.11.1
Reaction time trials AUC0.60.91.30.9-0.10.10.9-0.9-1.10.31.11.1-1.2-1.01.21.00.5-1.1-1.1-1.1-1.1-0.5-1.1-1.1-0.80.8-0.90.9
Run reversals in cocaine runway, females0.60.63.30.3-1.11.10.3-0.20.9-0.4-0.0-0.40.20.1-0.1-0.0-0.00.10.50.60.31.10.60.61.8-1.61.0-1.6
Run reversals in cocaine runway, males2.32.34.40.51.2-1.20.6-0.6-1.20.51.51.5-1.6-1.61.41.51.3-1.8-1.7-1.8-1.9-1.3-1.8-1.8-2.02.0-2.11.5
Latency to leave start box in cocaine runway0.80.91.6-0.5-0.50.5-0.50.60.80.8-1.1-1.01.11.1-1.1-0.8-0.91.31.11.21.3-0.11.21.10.6-0.81.2-1.2
Latency to leave start box in cocaine runway, F0.40.51.3-0.3-0.40.5-0.30.30.5-0.0-0.7-0.70.80.7-0.6-0.5-0.60.80.70.80.90.60.80.80.7-0.80.9-1.1
Latency to leave start box in cocaine runway, M0.10.10.2-0.0-0.20.2-0.10.10.00.5-0.3-0.20.20.3-0.3-0.1-0.10.40.20.20.3-0.30.20.2-0.10.10.3-0.2
Std. dev. time between licks in bursts0.81.02.90.20.8-0.90.4-0.4-0.3-0.01.30.9-1.2-1.31.21.01.1-1.7-1.2-1.2-1.4-0.3-1.2-1.1-0.70.7-1.40.1
Total sessions with >9 infusions1.71.94.1-1.60.7-0.6-1.61.62.01.0-1.5-1.61.61.5-1.5-1.6-1.61.31.51.51.4-0.21.51.50.7-0.81.0-1.1
Short access day 1 total inactive lever presses2.42.75.7-2.41.8-1.8-2.32.32.10.5-1.9-1.92.01.8-1.8-1.9-2.01.41.61.61.5-0.21.41.5-0.30.30.5-0.9
Short access day 10 total inactive lever presses1.61.810.0-1.81.9-1.9-1.71.71.23.2-0.9-1.21.00.8-1.1-1.0-1.00.50.70.60.6-2.60.60.5-1.01.1-0.3-0.4
Short access day 1 total infusions4.44.68.9-2.40.9-0.8-2.52.53.00.4-2.6-2.62.52.5-2.3-2.5-2.52.22.52.52.30.52.42.41.1-1.11.8-1.8
Short access day 10 total infusions5.66.29.4-2.0-0.40.5-2.02.13.0-0.5-2.8-2.92.82.8-2.8-2.8-2.72.82.93.12.91.73.03.02.5-2.42.8-2.2
Short access total infusions2.83.26.5-1.70.2-0.1-1.71.82.50.2-2.1-2.12.02.0-1.9-2.0-2.01.82.12.11.90.92.12.11.6-1.51.8-1.6
Short access day 1 locomotion3.63.96.9-1.90.4-0.3-2.02.02.61.0-2.4-2.32.32.4-2.3-2.3-2.12.12.32.32.30.22.32.21.2-1.21.9-1.8
Short access day 10 total locomotion3.03.45.1-1.70.2-0.1-1.81.82.30.3-2.1-2.22.22.0-2.2-2.2-1.91.92.12.22.10.82.12.11.3-1.41.8-2.2
Short access total locomotion2.93.05.3-1.60.1-0.1-1.61.72.30.8-2.0-2.02.02.0-2.0-2.0-1.81.82.02.01.90.42.02.01.3-1.41.7-2.2
One hour access (0.3 mA shock)5.05.811.6-3.42.8-2.7-3.43.32.82.7-2.7-2.72.72.5-2.8-2.8-2.72.12.22.02.1-1.81.91.8-0.40.70.5-1.0
Compulsive drug intake2.72.84.92.0-1.21.12.0-2.0-1.6-0.72.01.9-2.1-2.02.12.22.1-2.1-1.8-1.7-1.90.4-1.7-1.70.1-0.2-1.00.6
One hour access (shock baseline)5.36.211.3-3.32.6-2.5-3.43.32.52.2-2.9-2.83.02.8-3.0-3.1-3.02.62.42.22.5-1.52.22.1-0.60.90.8-0.6
Social response proportion0.40.41.80.6-1.31.30.6-0.5-0.2-0.2-0.4-0.10.20.4-0.3-0.10.20.60.40.40.50.80.40.31.0-1.00.9-0.4
Social responses0.20.20.60.7-0.60.60.7-0.6-0.4-0.50.40.5-0.6-0.40.60.50.8-0.5-0.4-0.4-0.40.5-0.3-0.30.3-0.3-0.10.3
Social time0.30.41.60.8-0.50.50.8-0.8-0.5-0.20.70.7-0.8-0.60.90.81.3-0.6-0.6-0.6-0.60.2-0.6-0.70.2-0.1-0.3-0.1
Soleus weight1.54.515.2-3.43.9-3.9-3.23.11.72.6-1.8-1.91.81.5-2.1-1.5-1.40.91.00.70.9-2.50.70.5-2.22.1-1.0-0.4
Bone: stiffness1.32.07.01.2-2.62.71.1-1.0-0.4-2.6-0.4-0.20.40.5-0.3-0.3-0.11.20.70.91.02.60.90.92.1-2.11.9-0.8
Tibialis anterior weight7.023.847.16.9-5.04.96.8-6.8-5.8-4.95.65.7-5.5-5.35.35.45.9-4.2-4.8-4.4-4.42.4-4.4-4.30.3-0.3-1.82.8
Time to tail flick, vehicle, before self-admin0.20.21.00.4-1.01.00.4-0.30.0-0.1-0.1-0.10.10.1-0.1-0.1-0.20.30.30.40.30.40.40.40.9-0.80.7-0.6
Time to tail flick, vehicle, after self-admin0.60.62.61.0-1.51.51.0-0.90.1-0.30.30.3-0.5-0.50.60.60.6-0.4-0.10.0-0.30.90.00.01.4-1.60.7-0.8
Time to tail flick, test, before self-admin1.41.44.5-1.1-0.00.0-1.01.11.70.5-1.3-1.41.21.2-1.2-0.9-0.80.91.31.31.10.71.31.31.2-1.41.2-2.1
Time to tail flick, test, after self-admin0.00.00.30.1-0.00.00.1-0.1-0.20.5-0.10.1-0.1-0.10.10.3-0.1-0.1-0.1-0.2-0.1-0.4-0.1-0.2-0.20.2-0.10.4
Delta time to tail flick, vehicle, before/after SA0.20.21.30.6-0.90.90.5-0.50.10.10.00.1-0.2-0.20.20.30.6-0.10.00.1-0.10.40.10.00.9-1.10.5-0.6
Delta time to tail flick, test, before/after SA3.12.86.91.6-0.10.11.6-1.6-2.1-0.11.82.0-1.9-1.81.91.71.4-1.6-1.9-2.0-1.8-1.0-1.9-1.9-1.41.6-1.62.6
Tibia length0.82.26.31.9-1.01.01.8-1.9-2.5-1.81.41.7-1.4-1.31.41.41.5-0.6-1.5-1.4-1.10.5-1.4-1.5-1.11.0-0.92.5
Ambulatory time before self-admin0.10.10.50.4-0.70.70.3-0.3-0.6-0.4-0.30.00.10.2-0.2-0.2-0.10.60.20.20.30.10.20.2-0.10.10.40.4
Ambulatory time after self-admin0.80.92.2-0.6-0.20.3-0.70.70.4-0.5-1.2-1.01.21.2-1.2-1.2-1.21.51.11.11.30.51.11.10.2-0.21.0-0.3
Bone: tissue strength0.30.30.9-0.2-0.40.5-0.20.20.1-0.5-0.6-0.50.70.6-0.5-0.4-0.50.90.60.60.80.60.60.50.4-0.40.7-0.3
Total heroin consumption2.42.86.82.6-2.42.42.5-2.5-2.0-2.11.51.9-1.7-1.41.71.51.3-1.0-1.3-1.2-1.11.7-1.1-1.00.7-0.80.01.5
Bone: trabecular number1.52.45.90.1-1.92.0-0.10.10.9-1.1-1.2-1.21.31.3-1.1-1.4-1.31.91.71.81.81.51.81.82.2-2.22.4-0.5
Bone: trabecular spacing0.20.30.9-0.30.9-0.9-0.20.2-0.00.10.40.2-0.3-0.50.00.50.3-0.7-0.5-0.5-0.6-0.1-0.6-0.5-0.70.7-0.9-0.6
Bone: trabecular thickness1.72.03.2-1.1-0.20.2-1.21.21.60.9-1.8-1.61.71.8-1.3-1.7-1.61.71.71.71.8-0.01.71.71.2-1.21.6-0.8
Bone: trabecular tissue density1.62.27.2-2.02.7-2.7-1.91.90.62.7-1.0-1.00.90.9-1.0-0.9-0.90.60.40.20.4-2.50.20.1-2.01.9-1.00.4
Water consumed over 24 hours0.30.41.10.9-1.11.00.8-0.8-0.4-1.10.40.4-0.4-0.40.60.40.4-0.3-0.3-0.1-0.20.9-0.2-0.10.6-0.60.3-0.0
Number of responses in last shaping day0.50.53.0-0.91.2-1.2-0.90.80.91.7-0.4-0.30.30.4-0.2-0.2-0.3-0.20.20.0-0.0-1.30.10.0-0.70.6-0.4-0.3