Atosb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Atosb 0.03 0.03 5.6e-03 0.02 0.02 0.02 0.02 5.3e-03 5.9e-03 1.1e-02 9.0e-03
2 IC mRNA stability Atosb 0.11 0.09 3.2e-03 0.03 0.03 0.01 0.03 2.0e-02 2.2e-02 1.6e-01 1.8e-02
3 Brain alternative TSS XM_039109529.1 0.04 0.03 8.6e-04 0.03 0.01 0.03 0.03 6.6e-04 1.8e-02 4.8e-04 1.3e-03
4 Brain intron excision ratio chr5_62061114_62064183 0.06 0.04 4.8e-05 0.04 0.02 0.04 0.02 1.5e-04 8.0e-03 4.5e-05 9.4e-03
5 PL isoform ratio XM_039109529.1 0.02 0.02 6.1e-03 0.02 0.02 0.01 0.02 2.9e-03 4.6e-03 4.3e-02 5.3e-03
6 BLA alternative TSS XM_039109529.1 0.08 0.06 2.9e-03 0.03 0.03 0.03 0.03 9.1e-03 1.6e-02 1.1e-02 1.1e-02
7 PL intron excision ratio chr5_62061114_62064183 0.03 0.02 2.3e-03 0.02 0.02 0.01 0.01 2.6e-03 4.4e-03 9.9e-03 9.2e-03
8 Liver gene expression Atosb 0.18 0.1 0.0e+00 0.15 0.17 0.16 0.15 9.5e-17 2.8e-18 5.8e-17 9.7e-17
9 Brain isoform ratio NM_001013931.2 0.03 0.03 7.2e-03 0.03 0.02 0.03 0.03 1.4e-03 5.4e-03 2.2e-03 1.5e-03
10 Brain alternative TSS XM_039109529.1 0.04 0.03 5.7e-04 0.03 0.01 0.04 0.03 7.0e-04 1.4e-02 3.1e-04 2.0e-03
11 pVTA alternative TSS XM_039109529.1 0.06 0.04 1.7e-05 0.04 0.05 0.04 0.04 3.7e-04 1.3e-04 3.6e-04 4.9e-04
12 pVTA isoform ratio XM_039109529.1 0.06 0.04 3.5e-05 0.03 0.04 0.04 0.03 1.4e-03 4.4e-04 6.3e-04 9.6e-04
13 pVTA alternative TSS XM_039109529.1 0.05 0.04 1.3e-04 0.03 0.04 0.03 0.03 2.8e-03 8.1e-04 1.6e-03 2.7e-03
14 BLA isoform ratio XM_039109529.1 0.06 0.04 7.7e-03 0.01 0.03 0.02 0.02 8.2e-02 1.0e-02 4.5e-02 4.3e-02
15 IL alternative TSS XM_039109528.2 0.14 0.1 6.1e-03 0.06 0.06 0.05 0.06 1.6e-02 1.4e-02 2.7e-02 1.4e-02
16 Brain isoform ratio XM_039109529.1 0.05 0.04 3.3e-04 0.03 0.01 0.04 0.02 6.2e-04 2.5e-02 2.0e-04 3.0e-03
17 Adipose mRNA stability Atosb 0.11 0.07 1.6e-11 0.1 0.1 0.1 0.1 2.4e-11 3.1e-11 1.2e-10 2.4e-11
18 pVTA intron excision ratio chr5_62061114_62064183 0.07 0.06 6.1e-05 0.04 0.03 0.04 0.04 1.5e-04 9.9e-04 8.1e-04 6.5e-04
19 BLA alternative TSS XM_039109529.1 0.06 0.05 9.7e-03 0.01 0.02 0.01 0.02 1.0e-01 2.3e-02 8.4e-02 3.7e-02
20 NAcc gene expression Atosb 0.04 0.03 1.1e-07 0.05 0.02 0.04 0 1.1e-07 7.0e-04 2.2e-07 8.3e-02
21 Adipose gene expression Atosb 0.23 0.15 0.0e+00 0.19 0.19 0.2 0.2 1.2e-20 1.1e-20 2.9e-21 1.4e-21
22 Liver alternative TSS XM_039109528.2 0.03 0.02 7.4e-04 0.04 0.03 0.03 0.03 2.8e-05 2.2e-04 1.6e-04 2.3e-04
23 Brain gene expression Atosb 0.05 0.04 5.7e-04 0.03 0.02 0.01 0.01 9.6e-04 5.5e-03 2.6e-02 6.7e-02
24 Liver alternative TSS XM_063287372.1 0.05 0.03 1.5e-05 0.06 0.04 0.05 0.05 4.9e-07 1.6e-05 1.5e-06 2.9e-06
25 PL alternative TSS XM_039109529.1 0.03 0.02 4.0e-03 0 0.01 0.01 0.01 9.8e-02 1.6e-02 3.0e-02 6.9e-02
26 BLA isoform ratio XM_039109530.1 0.08 0.06 8.8e-03 0.01 0.02 0.01 0.01 1.3e-01 4.8e-02 8.1e-02 1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density1.22.23.6-1.4-1.71.61.71.51.31.31.5-1.41.6-1.5-1.6-1.3-1.2-1.01.51.81.0-1.0-1.71.9-1.9-1.81.8-0.4-0.4
Area under the delay curve0.50.71.40.71.1-0.9-1.0-0.6-0.6-0.6-1.00.7-1.00.80.90.70.60.4-1.2-1.2-0.80.51.0-1.11.01.1-0.90.10.4
BMI with tail1.55.27.1-2.2-2.52.42.52.22.32.32.5-2.32.4-2.5-2.5-2.3-2.2-1.92.32.61.9-2.1-2.72.4-2.4-2.62.4-1.40.3
BMI without tail1.36.98.8-2.7-2.92.82.72.52.72.72.8-2.72.8-2.8-2.9-2.7-2.6-2.32.62.92.3-2.5-3.02.5-2.7-2.82.6-1.90.7
Body weight3.314.317.8-4.2-4.04.03.94.14.14.13.7-4.03.9-4.0-3.9-4.1-4.1-4.03.73.43.7-4.1-3.53.4-3.4-3.43.2-3.62.3
Weight adjusted by age0.10.20.7-0.3-0.40.40.40.70.50.50.4-0.50.3-0.3-0.3-0.5-0.5-0.80.20.20.1-0.6-0.10.2-0.0-0.1-0.2-0.80.9
Bone surface0.81.51.9-1.4-1.41.31.41.41.21.21.2-1.31.3-1.3-1.3-1.2-1.2-1.21.21.31.1-1.2-1.21.4-1.4-1.31.2-0.90.4
Bone volume0.61.21.9-1.1-1.31.21.21.11.01.01.1-1.11.2-1.1-1.2-1.0-0.9-0.81.11.30.8-0.9-1.21.4-1.3-1.31.3-0.5-0.1
Breakpoint value in progressive ratio session0.91.66.20.31.1-0.6-1.3-0.40.10.1-1.60.2-1.01.01.20.50.1-0.2-1.3-1.9-0.0-0.21.9-2.02.01.9-2.0-1.32.5
Number of licking bursts2.16.37.9-2.4-2.62.72.62.32.52.52.8-2.52.7-2.7-2.7-2.6-2.4-2.12.82.72.7-2.3-2.72.6-2.6-2.62.8-1.60.4
Context. condit. distance diff. score0.10.10.20.50.3-0.4-0.3-0.4-0.4-0.4-0.30.5-0.30.40.30.40.40.5-0.2-0.2-0.30.50.2-0.20.30.3-0.30.5-0.4
Locomotion velocity, session 11.31.411.0-1.1-0.10.60.31.21.11.1-0.0-1.10.3-0.5-0.2-1.0-1.4-1.90.2-0.31.1-1.70.3-0.40.50.4-0.6-2.63.3
Locomotion distance, session 10.50.63.6-0.8-0.30.50.30.90.90.90.3-0.90.4-0.6-0.4-0.8-1.0-1.30.30.10.7-1.2-0.1-0.10.1-0.00.1-1.61.9
Locomotion velocity, session 22.32.73.9-1.5-1.91.81.91.71.51.51.9-1.51.8-1.7-1.8-1.6-1.5-1.41.71.91.3-1.3-1.92.0-2.0-1.81.8-0.8-0.1
Locomotion distance, session 22.33.34.7-2.1-1.71.81.61.92.02.01.7-2.11.7-1.9-1.8-2.0-2.1-2.11.61.51.8-2.2-1.51.2-1.3-1.51.6-2.21.7
Locomotion velocity, session 30.20.32.3-0.40.10.2-0.10.40.50.5-0.2-0.40.1-0.2-0.0-0.4-0.6-0.80.1-0.20.5-0.70.3-0.40.30.3-0.4-1.21.5
Locomotion distance, session 32.22.53.8-1.8-1.51.71.41.81.81.81.4-1.81.5-1.6-1.5-1.8-1.9-1.91.41.21.6-1.9-1.21.1-1.2-1.21.1-2.01.6
Stereotopy head waving bouts, day 30.30.31.70.10.6-0.3-0.4-0.1-0.1-0.1-0.70.1-0.40.40.50.1-0.1-0.3-0.4-0.70.1-0.20.7-0.60.80.8-0.9-0.81.3
Stereotopy head waving duration, day 30.30.40.90.50.7-0.6-0.6-0.5-0.5-0.5-0.80.5-0.60.60.70.50.40.3-0.5-0.7-0.20.30.8-0.70.90.8-0.9-0.10.5
Locomotion velocity, session 70.10.10.10.30.3-0.3-0.4-0.3-0.3-0.3-0.30.3-0.30.30.30.30.30.3-0.3-0.2-0.30.30.2-0.30.30.3-0.30.2-0.1
Locomotion distance, session 70.20.30.7-0.7-0.50.50.40.50.60.60.4-0.70.4-0.5-0.5-0.6-0.7-0.70.40.40.5-0.7-0.30.3-0.3-0.40.4-0.80.8
Stereotopy head waving bouts, day 71.11.32.0-1.2-1.11.21.21.31.31.30.9-1.31.2-1.1-1.1-1.2-1.3-1.31.30.91.4-1.3-0.91.0-0.9-0.90.6-1.31.1
Stereotopy head waving duration, day 70.60.71.2-0.9-0.80.90.90.90.90.90.6-0.90.9-0.8-0.8-0.9-0.9-0.91.00.71.1-0.9-0.70.8-0.7-0.60.4-0.90.7
Locomotion velocity, session 80.10.21.5-0.30.00.1-0.10.20.30.3-0.0-0.30.0-0.10.0-0.3-0.4-0.60.1-0.10.6-0.60.2-0.30.20.2-0.3-0.91.2
Locomotion distance, session 80.30.41.6-0.7-0.30.50.30.60.70.70.3-0.70.4-0.5-0.4-0.7-0.8-0.90.40.30.7-0.9-0.30.1-0.1-0.10.3-1.11.2
Degree of sensitization distance1.01.11.41.21.1-1.1-1.1-1.2-1.2-1.2-1.11.1-1.11.11.11.11.21.2-1.0-1.0-1.11.11.0-0.90.91.0-0.81.0-0.7
Degree of sensitization stereotypy1.31.41.8-1.2-1.21.31.31.21.31.31.1-1.21.3-1.2-1.2-1.2-1.2-1.11.41.11.3-1.2-1.11.2-1.2-1.11.0-1.00.5
Conditioned locomotion0.10.11.0-0.00.4-0.1-0.4-0.10.20.2-0.4-0.0-0.20.20.2-0.0-0.2-0.2-0.2-0.50.3-0.30.4-0.60.60.5-0.3-0.71.0
Cocaine response after cond. corrected1.42.13.71.21.7-1.5-1.7-1.4-1.1-1.1-1.61.1-1.61.51.61.20.90.8-1.6-1.8-1.00.71.9-1.91.81.8-1.7-0.11.2
Cocaine response after cond. not corrected1.11.73.11.01.5-1.3-1.5-1.2-0.9-0.9-1.50.9-1.41.31.40.90.70.5-1.4-1.7-0.90.41.7-1.81.71.7-1.6-0.41.4
Cocaine response before conditioning0.81.01.2-1.0-1.11.01.01.01.01.01.0-1.11.1-1.0-1.1-1.0-0.9-0.81.01.10.9-0.9-1.11.0-1.1-1.11.0-0.60.1
Saline control response1.01.33.1-1.3-0.81.10.81.21.31.30.8-1.31.1-1.1-0.9-1.3-1.4-1.51.10.61.6-1.5-0.60.5-0.6-0.60.6-1.81.7
Bone: connectivity density0.60.92.1-0.8-1.21.01.31.00.70.71.0-0.81.0-1.0-1.0-0.8-0.6-0.51.01.20.4-0.5-1.21.4-1.3-1.21.20.1-0.7
Bone: cortical apparent density0.20.32.10.3-0.20.10.2-0.4-0.2-0.20.30.10.2-0.1-0.20.20.40.70.30.7-0.00.5-0.70.5-0.4-0.60.51.0-1.4
Bone: cortical area2.64.26.4-2.0-2.42.22.01.72.02.02.4-1.92.3-2.2-2.3-1.9-1.7-1.22.22.51.8-1.5-2.52.2-2.5-2.52.5-0.6-0.6
Bone: cortical porosity0.20.30.40.50.4-0.6-0.4-0.4-0.6-0.6-0.50.6-0.50.50.50.60.60.5-0.5-0.5-0.60.60.5-0.30.30.5-0.40.6-0.4
Bone: cortical porosity0.00.00.10.00.0-0.10.00.1-0.1-0.1-0.10.1-0.10.10.10.00.0-0.10.0-0.20.00.00.2-0.0-0.00.2-0.1-0.00.1
Bone: cortical thickness0.91.63.5-1.0-1.41.31.10.51.01.01.5-0.91.4-1.2-1.4-0.9-0.60.01.31.90.8-0.4-1.81.4-1.6-1.81.90.4-1.5
Bone: cortical thickness0.30.31.50.50.3-0.4-0.5-0.8-0.5-0.5-0.30.5-0.30.40.30.60.71.1-0.40.1-0.60.8-0.1-0.20.2-0.00.01.1-1.2
Bone: cortical tissue density0.10.21.80.3-0.1-0.00.1-0.5-0.2-0.20.20.20.10.0-0.10.20.40.70.20.6-0.10.5-0.60.4-0.3-0.50.41.0-1.3
Condit. Reinf. active minus inactive responses0.50.61.1-0.6-0.80.81.00.80.80.81.0-0.70.8-0.8-0.9-0.8-0.7-0.70.80.90.7-0.6-0.91.0-0.9-0.80.9-0.4-0.0
Condit. Reinf. active-inactive response ratio0.60.71.01.00.8-0.8-0.8-1.0-0.9-0.9-0.70.9-0.80.80.80.90.90.9-0.8-0.6-0.80.90.6-0.60.80.6-0.70.9-0.7
Condit. Reinf. active responses2.93.75.3-1.7-2.12.12.32.01.91.92.2-1.82.1-2.0-2.1-1.9-1.8-1.82.12.11.8-1.7-2.12.3-2.1-2.02.1-1.10.2
Condit. Reinf. inactive responses3.54.56.1-2.0-2.42.22.52.22.02.02.5-2.02.2-2.3-2.3-2.1-1.9-1.82.22.41.8-1.8-2.42.5-2.4-2.42.3-1.1-0.0
Incentive salience index mean4.55.87.2-2.3-2.52.62.72.62.52.52.6-2.42.5-2.5-2.5-2.5-2.5-2.52.52.32.5-2.4-2.32.5-2.4-2.22.4-1.91.0
Condit. Reinf. lever presses10.315.418.9-4.0-3.94.14.24.34.14.14.0-4.14.0-4.1-4.0-4.2-4.2-4.34.03.54.2-4.2-3.53.7-3.6-3.43.6-3.72.4
Condit. Reinf. active minus inactive responses0.60.91.3-1.1-1.11.01.00.90.90.91.0-1.01.0-1.0-1.0-0.9-0.8-0.71.01.10.8-0.8-1.01.0-1.0-1.11.1-0.4-0.1
Condit. Reinf. active-inactive response ratio0.10.10.3-0.4-0.50.30.30.20.20.20.5-0.20.3-0.3-0.4-0.2-0.2-0.10.30.50.0-0.1-0.40.4-0.5-0.50.50.2-0.5
Condit. Reinf. active responses2.33.34.3-2.1-2.01.91.91.91.91.91.8-1.91.9-1.9-1.9-1.8-1.8-1.71.81.91.5-1.7-1.81.8-1.7-1.92.0-1.20.4
Condit. Reinf. inactive responses2.53.85.1-2.0-2.12.12.12.02.02.01.9-2.02.2-2.1-2.1-1.9-1.8-1.52.12.11.8-1.6-2.22.1-1.9-2.22.3-1.0-0.0
Condit. Reinf. lever presses2.63.85.9-1.9-2.32.12.21.81.71.72.1-1.82.2-2.0-2.2-1.8-1.6-1.22.12.31.6-1.4-2.32.4-2.2-2.42.4-0.5-0.7
Condit. Reinf. lever reinforcers received2.73.85.0-2.2-2.22.12.12.12.02.02.0-2.12.1-2.1-2.1-2.0-1.9-1.82.02.01.7-1.8-2.02.0-1.9-2.12.1-1.30.4
Conditioned reinforcement - actives0.00.10.4-0.10.0-0.1-0.10.1-0.2-0.2-0.30.2-0.00.20.20.0-0.10.00.4-0.50.7-0.10.6-0.20.30.40.3-0.30.4
Conditioned reinforcement - inactives0.20.41.00.50.9-0.7-0.9-0.7-0.7-0.7-0.90.6-0.60.70.70.50.40.6-0.2-0.90.20.41.0-1.01.00.7-0.30.00.4
Conditioned locomotion0.10.10.9-0.30.3-0.1-0.10.30.10.1-0.3-0.0-0.20.00.1-0.2-0.3-0.3-0.1-0.50.2-0.40.5-0.30.30.40.1-0.70.9
Patch foraging indifference point 0 sec0.30.96.7-0.9-0.00.30.10.90.70.7-0.1-0.80.1-0.3-0.1-0.7-1.0-1.50.0-0.50.8-1.30.5-0.50.50.5-0.6-2.02.6
Patch foraging indifference point AUC4.711.214.7-3.7-3.73.53.73.83.53.53.5-3.63.4-3.5-3.4-3.5-3.5-3.73.22.92.9-3.5-2.93.3-3.3-3.23.0-2.91.7
Delay disc. indifference point, 0s delay1.01.12.21.01.2-1.1-1.1-0.8-0.9-0.9-1.31.0-1.21.11.21.00.90.6-1.2-1.5-0.80.71.3-1.31.41.5-1.30.20.4
Delay disc. indifference point, 16s delay0.91.32.80.81.5-1.0-1.4-0.8-0.5-0.5-1.40.8-1.11.11.20.90.70.4-1.3-1.6-0.40.51.5-1.61.71.6-1.4-0.21.0
Delay disc. indifference point, 2s delay0.00.10.3-0.0-0.10.10.20.10.00.00.2-0.00.2-0.2-0.2-0.1-0.00.10.20.20.10.0-0.30.4-0.4-0.30.40.3-0.5
Delay disc. indifference point, 24s delay0.10.10.20.40.3-0.2-0.3-0.4-0.1-0.1-0.30.4-0.30.30.30.40.40.3-0.5-0.3-0.40.40.2-0.30.30.3-0.30.3-0.2
Delay disc. indifference point, 4s delay0.10.10.50.30.5-0.4-0.3-0.2-0.3-0.3-0.40.3-0.50.30.30.30.20.2-0.7-0.5-0.60.20.4-0.40.30.4-0.30.10.1
Delay disc. indifference point, 8s delay0.00.00.1-0.10.0-0.00.10.10.00.00.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.20.0-0.3-0.1-0.10.1-0.2-0.10.2-0.10.1
Indifference point function ln k1.44.15.42.22.3-2.1-2.3-2.3-2.0-2.0-2.22.2-2.12.12.12.12.12.1-2.0-1.9-1.72.01.9-2.22.12.1-1.81.5-0.7
Indifference point function log k1.44.15.42.22.3-2.1-2.3-2.3-2.0-2.0-2.22.2-2.12.12.12.12.12.1-2.0-1.9-1.72.01.9-2.22.12.1-1.81.5-0.7
Patch foraging total patch changes 0 sec0.41.26.6-1.3-0.50.70.51.31.11.10.3-1.20.5-0.7-0.5-1.1-1.4-1.80.5-0.11.2-1.60.1-0.10.00.1-0.1-2.22.6
Patch foraging total patch changes 12 sec1.92.63.3-1.7-1.81.71.81.81.71.71.7-1.71.7-1.7-1.6-1.7-1.7-1.81.71.41.6-1.6-1.31.6-1.6-1.51.5-1.30.7
Patch foraging total patch changes 18 sec0.41.12.0-1.3-1.11.01.11.31.11.11.1-1.20.9-1.0-0.9-1.1-1.2-1.40.80.70.8-1.2-0.60.8-0.8-0.80.6-1.21.0
Patch foraging total patch changes 24 sec0.93.15.3-2.1-1.91.81.92.11.81.81.7-2.01.7-1.8-1.6-1.9-2.0-2.31.71.21.7-2.0-1.21.5-1.6-1.41.3-1.91.5
Patch foraging total patch changes 6 sec2.33.87.1-2.3-1.81.91.82.32.22.21.7-2.31.8-1.9-1.7-2.2-2.3-2.71.71.22.0-2.4-1.11.3-1.4-1.31.1-2.62.4
Patch foraging time to switch 0 sec1.14.26.82.52.1-2.0-2.2-2.5-2.1-2.1-2.02.5-1.92.11.92.22.32.6-1.9-1.6-1.92.31.7-1.81.71.8-1.42.2-1.7
Patch foraging water rate 0 sec0.72.64.5-2.0-1.51.51.51.91.71.71.4-1.91.4-1.6-1.5-1.8-1.9-2.11.31.21.6-1.9-1.31.1-1.0-1.21.0-2.01.8
Patch foraging water rate 12 sec0.00.00.4-0.20.10.1-0.2-0.00.20.2-0.1-0.30.0-0.00.0-0.1-0.2-0.2-0.0-0.10.1-0.30.0-0.30.10.0-0.1-0.50.6
Patch foraging water rate 18 sec0.20.40.9-0.5-0.70.70.60.40.50.50.6-0.60.8-0.6-0.7-0.5-0.4-0.10.90.80.7-0.3-1.00.7-0.8-0.91.00.1-0.6
Patch foraging water rate 24 sec0.10.21.80.3-0.1-0.1-0.0-0.4-0.4-0.40.10.30.00.1-0.00.30.50.60.10.3-0.40.6-0.40.2-0.3-0.30.41.0-1.3
Patch foraging water rate 6 sec0.71.11.7-1.1-0.91.10.80.91.01.00.9-1.11.1-1.1-1.1-1.1-1.1-0.81.21.11.3-1.1-1.20.8-0.9-0.91.3-0.90.5
Seeking ratio, delayed vs. immediate footshock2.84.05.3-1.9-2.02.32.11.92.32.32.1-2.02.3-2.1-2.2-2.1-2.0-1.72.12.11.7-1.9-2.22.0-1.9-2.12.1-1.40.5
Distance traveled before self-admin2.55.49.6-2.4-2.02.72.02.43.13.12.0-2.42.6-2.4-2.3-2.5-2.6-2.42.31.92.9-2.6-1.91.7-1.6-1.52.0-2.51.9
Distance traveled after self-admin1.22.04.5-1.1-1.21.61.31.01.51.51.5-1.11.7-1.5-1.6-1.4-1.2-0.71.81.71.9-1.1-1.71.5-1.4-1.42.1-0.6-0.2
Extensor digitorum longus weight5.120.324.4-4.8-4.74.94.74.64.94.94.6-4.74.8-4.7-4.7-4.7-4.6-4.54.74.44.9-4.5-4.24.1-4.2-4.34.2-3.72.0
Bone: elastic displacement5.57.010.02.82.5-2.8-2.6-2.9-2.9-2.9-2.42.8-2.72.72.62.92.92.8-2.8-2.2-3.22.92.2-2.42.22.1-2.42.8-2.0
Bone: elastic work2.53.39.42.01.3-1.7-1.5-2.2-2.0-2.0-1.12.0-1.51.61.42.02.32.6-1.5-0.6-2.12.50.7-0.90.90.7-0.93.0-3.1
Bone: endosteal estimation1.22.94.3-1.9-1.71.81.72.01.91.91.7-1.81.7-1.7-1.6-1.9-1.9-2.11.71.21.9-2.0-1.21.5-1.6-1.31.1-2.01.6
Bone: endosteal perimeter1.22.84.4-1.9-1.61.71.51.91.91.91.6-1.81.6-1.7-1.5-1.9-2.0-2.11.51.11.8-2.0-1.21.2-1.4-1.21.2-2.11.8
Epididymis fat weight0.31.32.0-1.0-1.41.21.41.11.11.11.4-1.01.2-1.2-1.3-1.1-1.0-1.01.11.30.7-1.0-1.41.4-1.4-1.31.2-0.5-0.1
Delta time in closed arm before/after self-admin0.60.61.4-0.4-0.90.80.80.20.60.61.0-0.40.9-0.7-0.8-0.5-0.3-0.00.81.20.3-0.2-1.21.0-1.0-1.00.90.3-0.9
Delta time in open arm before/after self-admin0.30.40.90.30.8-0.7-0.7-0.3-0.5-0.5-0.80.4-0.70.60.70.50.30.1-0.5-1.00.20.21.0-0.90.80.8-0.8-0.20.7
Diff in mean of infusions in LGA sessions0.10.10.70.4-0.0-0.2-0.1-0.5-0.3-0.3-0.00.4-0.10.20.10.30.40.7-0.00.1-0.00.5-0.20.0-0.1-0.20.10.7-0.8
Delay discount exponential model param0.40.61.3-0.6-1.00.80.90.50.50.50.9-0.60.9-0.7-0.8-0.6-0.5-0.31.11.10.8-0.4-0.91.0-0.9-1.00.8-0.0-0.4
Extinction: sum of active levers before priming2.53.86.02.12.4-1.9-2.3-2.0-1.5-1.5-2.31.9-1.92.12.11.91.81.8-2.0-2.2-0.91.72.2-2.32.32.2-2.01.0-0.0
Active lever presses in extinction session 60.40.40.70.50.6-0.4-0.7-0.6-0.2-0.2-0.70.5-0.50.70.70.60.60.6-0.7-0.8-0.40.50.8-0.70.60.6-0.80.30.0
Bone: final force1.93.14.0-1.9-2.01.91.71.61.81.82.0-1.81.9-1.9-1.9-1.8-1.7-1.41.91.91.8-1.6-1.91.8-1.9-1.91.9-1.10.2
Bone: final moment1.62.63.5-1.7-1.91.71.51.41.61.61.8-1.51.8-1.7-1.8-1.6-1.5-1.11.71.81.5-1.3-1.81.7-1.8-1.81.8-0.8-0.1
Food consumed during 24 hour testing period0.61.21.7-1.2-1.01.10.91.01.21.21.1-1.21.1-1.1-1.1-1.2-1.2-1.11.11.01.3-1.3-1.00.8-0.9-1.01.0-1.20.9
Glucose2.64.25.3-2.3-2.22.12.22.22.12.12.1-2.32.0-2.1-2.1-2.2-2.1-2.12.02.02.0-2.1-2.01.9-1.9-2.01.8-1.81.0
Heart weight0.71.11.7-1.2-1.21.21.11.01.31.31.1-1.31.1-1.1-1.1-1.0-1.0-0.90.91.10.8-1.0-1.11.0-1.2-1.20.8-0.70.3
Delay discount hyperbolic model param0.30.40.9-0.4-0.90.70.70.40.40.40.7-0.40.8-0.6-0.6-0.5-0.3-0.21.00.90.6-0.3-0.70.8-0.7-0.80.60.1-0.5
Intermittent access intake day 1-15 change0.21.01.9-0.7-1.11.21.10.91.01.01.2-0.51.2-1.1-1.2-1.0-0.9-0.71.21.30.7-0.8-1.41.2-1.2-1.01.2-0.4-0.2
Intermittent access intake escalation0.20.91.9-0.6-1.11.11.00.70.90.91.2-0.41.1-1.0-1.1-0.9-0.7-0.51.11.30.6-0.6-1.41.2-1.2-1.01.2-0.2-0.4
Intermittent access intake escalation 20.91.53.2-0.6-1.31.31.30.70.90.91.4-0.51.5-1.2-1.4-1.0-0.7-0.41.61.61.0-0.6-1.81.5-1.5-1.51.80.1-1.0
Intermitt. access day 1 inactive lever presses0.11.82.7-1.4-1.21.41.21.41.61.61.4-1.41.3-1.4-1.4-1.5-1.5-1.41.11.41.3-1.5-1.41.1-1.0-1.21.0-1.40.9
Intermitt. access day 15 inactive lever presses0.00.10.3-0.0-0.20.40.00.10.50.50.20.00.4-0.3-0.3-0.4-0.4-0.20.30.30.5-0.4-0.4-0.10.10.00.1-0.50.5
Intermitt. access escalation Index0.20.71.2-0.8-0.70.90.81.01.11.10.6-0.90.8-0.9-0.8-0.9-0.9-0.90.60.60.7-1.0-0.90.6-0.6-0.50.3-1.00.7
Intermittent access day 1 total infusions0.92.75.81.31.7-1.7-1.7-1.2-1.5-1.5-2.21.4-1.71.71.91.51.21.0-1.6-2.4-0.91.02.3-2.02.22.2-1.90.20.9
Intermittent access day 15 total infusions0.00.00.10.1-0.10.00.0-0.0-0.1-0.1-0.10.30.10.00.00.00.00.10.2-0.20.2-0.00.20.00.10.20.1-0.00.0
Intermittent access terminal intake (last 3 days)0.10.10.8-0.0-0.20.20.10.10.10.1-0.10.10.3-0.1-0.1-0.2-0.2-0.00.7-0.20.9-0.30.10.00.10.20.5-0.30.4
Intermittent access total infusions0.10.10.5-0.10.1-0.1-0.10.1-0.2-0.2-0.40.1-0.00.10.2-0.0-0.1-0.10.3-0.60.7-0.20.6-0.30.40.40.1-0.50.7
Intermittent access day 1 locomotion1.22.34.41.01.7-1.7-1.5-1.0-1.4-1.4-1.91.1-1.71.61.71.31.10.8-1.7-2.1-1.20.92.1-1.81.91.9-1.80.20.7
Intermittent access day 15 total locomotion0.51.83.20.91.3-1.5-1.4-1.1-1.4-1.4-1.61.2-1.51.41.51.21.10.9-1.4-1.7-1.20.91.8-1.61.61.5-1.60.40.4
Intermittent access total locomotion1.82.23.21.31.5-1.7-1.5-1.4-1.8-1.8-1.71.5-1.61.61.61.51.41.4-1.3-1.7-1.31.41.7-1.41.51.6-1.31.0-0.4
Intermittent access standard deviation0.10.30.7-0.5-0.40.60.40.40.70.70.5-0.40.6-0.6-0.6-0.7-0.7-0.50.60.60.7-0.7-0.50.3-0.3-0.40.8-0.70.5
Left kidney weight0.42.94.9-2.1-1.61.71.41.82.02.01.5-2.01.6-1.6-1.5-1.8-2.0-2.11.51.12.0-2.0-1.21.0-1.1-1.10.6-2.22.0
Right kidney weight0.31.93.0-1.7-1.61.51.41.51.51.51.5-1.71.4-1.4-1.3-1.4-1.4-1.51.21.31.2-1.4-1.31.2-1.3-1.40.5-1.20.8
Cocaine induced anxiety0.00.10.20.40.4-0.4-0.3-0.4-0.5-0.5-0.30.4-0.20.30.30.30.30.20.1-0.40.10.30.3-0.20.40.30.30.2-0.2
Post-drug Anxiety0.60.71.9-0.9-0.70.80.81.00.70.70.7-0.90.8-0.8-0.7-0.9-0.9-1.11.10.31.4-1.0-0.50.7-0.6-0.61.0-1.00.8
Baseline Anxiety0.50.91.3-0.9-1.01.01.00.91.01.01.0-1.01.0-1.0-1.0-0.9-0.9-0.80.91.01.1-0.8-1.01.0-1.1-1.10.8-0.60.2
Tail length1.57.99.6-3.1-3.13.12.92.93.03.02.8-3.03.0-3.0-2.9-2.9-2.9-2.92.92.62.8-2.8-2.72.6-2.8-2.62.5-2.31.2
Length with tail1.67.010.6-3.1-2.62.92.53.03.13.12.3-2.92.7-2.6-2.4-2.9-3.0-3.32.51.82.8-3.1-1.82.0-2.0-1.81.7-3.12.6
Length without tail0.10.43.0-0.5-0.00.40.10.70.80.8-0.2-0.40.2-0.20.0-0.5-0.7-1.00.1-0.50.8-0.80.5-0.20.40.6-0.4-1.31.7
Times rat made contact with spout0.40.50.8-0.5-0.70.70.70.50.60.60.8-0.50.8-0.7-0.8-0.6-0.5-0.40.90.90.8-0.4-0.90.8-0.8-0.80.8-0.1-0.4
Lifetime Intake0.20.31.6-0.10.2-0.1-0.30.1-0.1-0.1-0.70.0-0.10.20.3-0.1-0.2-0.20.2-0.90.8-0.40.9-0.60.70.7-0.1-0.91.3
Liver weight, left0.00.00.2-0.10.1-0.1-0.2-0.00.00.0-0.0-0.0-0.10.10.20.0-0.0-0.1-0.2-0.30.0-0.10.2-0.20.10.1-0.4-0.30.5
Liver weight, right0.81.32.11.31.2-1.2-1.3-1.3-1.3-1.3-1.21.4-1.01.21.11.21.31.3-0.8-1.0-0.61.31.1-1.11.11.1-0.81.2-0.8
Locomotor activity0.00.00.0-0.0-0.00.10.10.10.10.1-0.0-0.10.1-0.1-0.1-0.1-0.1-0.10.10.10.1-0.1-0.1-0.0-0.0-0.10.1-0.10.1
Locomotor testing distance0.10.30.80.30.6-0.4-0.6-0.3-0.3-0.3-0.70.2-0.50.40.50.20.1-0.1-0.5-0.7-0.2-0.00.7-0.80.90.7-0.5-0.40.9
Locomotor testing rearing0.31.12.2-1.1-0.91.00.91.11.01.00.8-1.21.1-1.1-1.1-1.2-1.2-1.21.20.71.5-1.3-0.80.8-0.6-0.81.2-1.31.0
Locomotion in novel chamber0.30.41.00.60.6-0.7-0.5-0.7-0.9-0.9-0.30.8-0.60.60.50.70.80.8-0.5-0.3-0.60.80.3-0.30.20.3-0.11.0-1.0
Locomotion in novel chamber post-restriction0.61.93.6-1.1-1.91.31.61.00.70.71.7-1.01.4-1.3-1.5-1.0-0.8-0.61.61.80.8-0.6-1.61.9-1.9-1.91.90.2-1.2
Fecal boli incidents, locomotor time 10.41.11.81.41.1-1.1-0.9-1.1-1.2-1.2-0.81.2-1.21.11.01.21.21.0-1.3-0.8-1.31.20.8-0.70.70.8-1.31.2-0.9
Change in fecal boli incidents, locomotor task0.80.81.5-1.1-0.90.90.81.01.01.00.7-1.20.8-0.8-0.7-1.0-1.1-1.10.80.41.1-1.1-0.40.5-0.5-0.50.5-1.21.2
Time >=10cm from walls, locomotor time 10.20.21.4-0.50.10.2-0.10.40.60.6-0.0-0.40.0-0.1-0.0-0.3-0.5-0.5-0.1-0.30.5-0.60.2-0.40.30.3-0.5-0.91.2
Bouts of movement, locomotor time 11.62.12.81.71.6-1.5-1.5-1.6-1.6-1.6-1.51.6-1.51.51.51.51.51.5-1.4-1.4-1.51.51.3-1.31.31.4-1.11.3-0.8
Total resting periods, locomotor time 12.42.83.81.91.7-1.7-1.6-1.9-1.9-1.9-1.61.9-1.61.71.61.81.91.8-1.6-1.5-1.81.91.3-1.31.31.4-1.31.8-1.3
Rest time, locomotor task time 11.22.07.01.70.7-1.1-0.8-1.7-1.7-1.7-0.61.8-0.91.10.91.51.71.9-0.9-0.5-1.81.90.5-0.10.10.4-0.52.5-2.7
Distance moved, locomotor task time 10.92.65.9-1.9-1.11.61.22.02.02.01.0-1.91.4-1.5-1.3-1.8-1.9-2.11.30.82.0-2.1-0.80.7-0.7-0.71.0-2.42.4
Vertical activity count, locomotor time 10.31.77.1-1.4-0.71.00.81.71.41.40.5-1.50.8-1.0-0.8-1.4-1.6-2.00.80.21.7-1.8-0.20.1-0.2-0.10.6-2.42.7
Time >=10cm from walls, locomotor time 20.00.10.3-0.3-0.30.30.20.40.40.40.3-0.40.2-0.3-0.3-0.4-0.4-0.50.20.20.2-0.4-0.30.1-0.0-0.2-0.0-0.50.6
Bouts of movement, locomotor time 20.10.50.8-0.7-0.40.50.70.80.60.60.7-0.80.5-0.8-0.8-0.8-0.8-0.70.60.60.8-0.8-0.80.7-0.6-0.60.9-0.60.3
Total resting periods, locomotor time 20.00.10.4-0.3-0.10.10.30.40.10.10.3-0.40.2-0.4-0.4-0.4-0.4-0.40.30.30.4-0.4-0.40.4-0.3-0.30.6-0.30.1
Rest time, locomotor task time 20.71.21.81.10.9-1.1-0.9-1.1-1.4-1.4-1.01.2-1.01.11.01.21.21.2-1.0-0.9-1.41.31.1-0.60.70.9-0.81.3-1.0
Distance moved, locomotor task time 20.60.81.8-0.6-0.91.00.90.70.80.81.0-0.61.0-0.9-1.0-0.8-0.7-0.51.01.10.6-0.6-1.31.1-1.0-1.01.3-0.3-0.2
Vertical activity count, locomotor time 20.40.91.3-0.8-0.91.00.91.11.01.00.9-1.00.9-1.0-0.9-1.1-1.1-1.10.90.81.0-1.1-1.00.7-0.7-0.70.9-1.10.9
Light reinforcement 10.62.611.9-1.7-0.61.20.51.51.91.90.6-1.81.0-1.3-1.0-1.8-2.1-2.21.00.32.2-2.3-0.4-0.30.2-0.00.3-3.13.4
Light reinforcement 20.61.410.5-1.0-0.00.50.11.11.11.1-0.2-0.90.3-0.4-0.1-0.9-1.3-1.70.3-0.81.5-1.60.8-0.60.50.8-0.7-2.53.2
Bone: marrow area1.33.14.2-1.9-1.81.91.82.01.91.91.8-1.81.8-1.8-1.7-1.9-1.9-2.11.81.42.0-2.0-1.41.6-1.7-1.41.2-1.81.3
Bone: maximum diameter2.55.06.8-2.2-2.52.42.42.22.22.22.6-2.12.4-2.4-2.4-2.3-2.1-1.82.42.42.2-2.0-2.42.4-2.6-2.42.5-1.30.2
Bone: maximum force3.36.58.0-2.7-2.82.82.52.42.62.62.8-2.52.8-2.7-2.8-2.6-2.4-2.12.72.82.5-2.3-2.72.6-2.7-2.72.7-1.60.4
Bone: maximum moment2.75.26.7-2.4-2.62.52.32.12.32.32.6-2.22.5-2.4-2.5-2.3-2.1-1.72.42.62.2-1.9-2.52.4-2.5-2.52.5-1.20.0
Mean time between licks in bursts0.10.40.70.70.6-0.7-0.7-0.7-0.7-0.7-0.60.7-0.70.70.70.70.70.7-0.7-0.6-0.80.70.6-0.70.50.6-0.60.6-0.4
Mean num. licks in bursts1.13.03.61.81.8-1.8-1.7-1.6-1.8-1.8-1.81.8-1.81.81.81.81.81.6-1.9-1.8-1.91.81.8-1.71.61.7-1.81.4-0.7
Cd content in liver1.01.11.6-1.3-1.11.10.91.01.21.21.0-1.21.1-1.1-1.1-1.2-1.2-0.91.10.90.9-1.2-0.91.0-1.0-0.91.0-1.10.7
Co content in liver0.40.51.20.50.9-0.7-1.0-0.4-0.5-0.5-0.80.4-0.70.70.80.50.40.1-0.8-1.0-0.50.31.0-1.11.01.0-0.9-0.20.7
Cu content in liver1.72.02.71.61.4-1.5-1.5-1.7-1.5-1.5-1.41.6-1.51.51.41.51.51.6-1.5-1.2-1.71.51.1-1.11.21.2-1.11.4-0.9
Fe content in liver0.81.02.50.71.2-1.0-1.4-0.9-0.7-0.7-1.20.7-1.01.01.10.80.60.5-1.0-1.3-0.60.51.3-1.61.41.3-1.3-0.10.8
K content in liver0.30.30.60.30.6-0.5-0.5-0.3-0.3-0.3-0.60.3-0.60.50.60.30.2-0.1-0.6-0.8-0.40.10.7-0.70.70.8-0.7-0.20.7
Mg content in liver0.80.91.41.00.9-1.0-0.8-0.8-1.0-1.0-0.91.0-1.11.01.11.00.90.5-1.1-1.2-1.00.81.1-0.90.81.2-1.10.5-0.0
Mn content in liver1.21.32.3-1.0-1.31.21.30.91.01.01.4-1.01.2-1.2-1.3-1.0-0.9-0.71.21.40.9-0.8-1.41.5-1.5-1.41.3-0.3-0.4
Na content in liver1.31.42.01.31.2-1.2-1.4-1.3-1.2-1.2-1.11.3-1.21.21.21.21.21.3-1.2-1.1-1.31.21.0-1.41.01.1-1.11.0-0.6
Rb content in liver5.26.08.82.52.7-2.6-3.0-2.7-2.5-2.5-2.52.5-2.62.62.62.52.42.3-2.5-2.6-2.22.32.6-2.82.52.6-2.41.6-0.5
Se content in liver2.42.84.5-1.5-1.81.82.01.61.61.61.8-1.61.8-1.8-1.8-1.6-1.5-1.11.91.91.7-1.4-1.92.1-1.9-1.91.9-0.8-0.1
Sr content in liver0.40.31.4-0.7-0.60.61.01.20.60.60.5-0.70.4-0.5-0.5-0.6-0.6-0.60.20.4-0.1-0.6-0.40.8-0.4-0.40.2-0.60.4
Zn content in liver0.10.10.3-0.2-0.40.30.30.30.20.20.4-0.20.2-0.3-0.3-0.2-0.2-0.20.10.4-0.2-0.1-0.40.5-0.5-0.40.40.1-0.3
Bone: minimum diameter0.00.10.40.1-0.1-0.1-0.0-0.2-0.2-0.20.10.3-0.10.10.00.20.30.4-0.00.0-0.30.3-0.00.2-0.3-0.00.10.5-0.6
Time in familiar zone, hab. session 10.80.96.11.00.3-0.5-0.2-1.0-1.0-1.0-0.20.9-0.40.50.30.91.21.5-0.30.3-1.01.4-0.30.3-0.2-0.30.22.0-2.5
Time in novel zone, hab. session 11.61.83.80.81.5-1.2-1.5-0.8-0.8-0.8-1.50.9-1.41.21.40.90.60.1-1.5-1.9-0.80.31.9-1.91.81.9-1.9-0.71.8
Total zone transitions, hab. session 10.00.00.1-0.1-0.10.10.10.10.10.10.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.10.2-0.2-0.1-0.10.1-0.2-0.10.3-0.0-0.1
Total locomotion distance, hab. session 10.50.61.6-0.5-0.90.71.00.50.40.40.9-0.50.8-0.7-0.8-0.5-0.3-0.10.71.10.1-0.1-1.11.3-1.1-1.11.20.5-1.1
Locomotion velocity, hab. session 11.62.34.1-1.4-1.81.61.91.41.31.31.7-1.31.6-1.6-1.7-1.4-1.2-1.01.51.81.0-1.0-1.92.0-1.9-1.92.0-0.3-0.6
Time in familiar zone, hab. session 20.80.93.41.10.7-0.8-0.6-1.1-1.1-1.1-0.51.1-0.80.80.61.01.21.4-0.8-0.2-1.31.30.2-0.20.40.3-0.21.7-1.8
Time in novel zone, hab. session 21.31.42.90.81.3-1.1-1.4-0.9-0.8-0.8-1.40.8-1.21.21.30.90.60.3-1.2-1.7-0.60.41.6-1.71.61.6-1.7-0.41.3
Total zone transitions, hab. session 20.70.91.9-1.0-0.70.90.81.11.11.10.8-1.00.8-0.9-0.8-1.1-1.1-1.40.70.61.0-1.2-0.60.5-0.6-0.50.6-1.41.3
Total locomotion distance, hab. session 20.91.21.5-1.1-1.11.11.21.11.11.11.2-1.11.1-1.1-1.1-1.1-1.1-1.11.11.11.0-1.0-1.11.2-1.1-1.11.2-0.80.4
Locomotion velocity, hab. session 21.21.52.0-1.2-1.31.31.41.31.21.21.4-1.21.3-1.3-1.3-1.3-1.2-1.31.21.31.2-1.2-1.31.4-1.3-1.31.4-0.90.3
Novel to familiar place preference ratio2.93.86.01.82.2-2.0-2.2-1.7-1.7-1.7-2.21.8-2.12.02.21.81.61.2-2.2-2.5-1.81.42.4-2.52.32.4-2.30.50.6
Novelty place preference4.05.17.52.12.5-2.4-2.6-2.1-2.1-2.1-2.52.2-2.42.42.52.11.91.6-2.5-2.7-2.11.72.6-2.72.62.7-2.60.90.3
Time in novel zone, NPP test5.16.29.12.42.8-2.6-2.8-2.3-2.3-2.3-2.82.4-2.72.62.72.42.11.8-2.7-3.0-2.31.92.9-3.02.83.0-2.81.00.3
Total zone transitions, NPP test0.81.22.7-1.2-0.91.10.91.31.31.30.9-1.30.9-1.0-0.9-1.2-1.4-1.50.80.71.1-1.4-0.70.6-0.5-0.60.7-1.61.6
Total locomotion distance, NPP test2.02.84.5-1.8-1.51.71.71.91.91.91.5-1.81.6-1.7-1.6-1.8-1.9-2.11.41.31.6-2.0-1.31.4-1.2-1.21.4-2.01.6
Locomotion velocity, NPP test2.63.75.2-2.1-1.92.02.02.22.12.11.8-2.01.9-2.0-1.9-2.1-2.1-2.31.71.71.8-2.1-1.71.7-1.6-1.61.7-2.01.5
Intraocular pressure2.23.64.8-2.2-2.02.01.92.22.02.01.7-2.11.9-2.0-1.9-2.1-2.1-2.11.91.62.1-2.2-1.51.4-1.6-1.51.5-2.01.5
Delta distance traveled before/after self-admin0.10.10.60.40.2-0.2-0.2-0.4-0.4-0.40.00.5-0.10.20.10.30.30.50.10.10.10.4-0.10.0-0.0-0.10.20.6-0.7
Delta ambulatory time before/after self-admin0.40.61.31.00.7-0.8-0.7-1.0-1.1-1.1-0.61.1-0.70.80.70.91.01.1-0.4-0.5-0.31.00.5-0.50.40.3-0.21.1-1.1
Parametrial fat weight0.10.20.9-0.10.3-0.2-0.6-0.30.10.1-0.3-0.1-0.40.20.30.0-0.1-0.0-0.6-0.3-0.5-0.20.4-0.80.80.4-0.7-0.61.0
Pavlov. Cond. lever latency7.29.110.93.13.1-3.2-3.2-3.2-3.2-3.2-3.03.1-3.23.23.13.23.23.1-3.2-2.8-3.33.12.7-2.92.82.7-2.92.7-1.6
Pavlov. Cond. magazine entry latency0.60.81.0-0.9-1.00.91.00.90.90.91.0-0.80.9-0.9-1.0-0.9-0.9-0.90.80.90.7-0.8-0.90.9-0.9-0.91.0-0.60.2
Pavlov. Cond. change in total contacts3.03.24.0-1.8-1.81.91.91.92.02.01.8-1.81.9-1.9-1.8-1.9-1.9-2.01.81.62.0-1.9-1.61.7-1.6-1.51.7-1.71.1
Pavlov. Cond. index score3.54.55.5-2.1-2.22.32.32.22.22.22.3-2.12.2-2.2-2.2-2.2-2.1-2.12.22.12.2-2.1-2.02.2-2.1-2.02.2-1.60.7
Pavlov. Cond. latency score3.24.15.0-2.0-2.12.22.22.12.12.12.2-2.02.1-2.1-2.1-2.1-2.1-2.02.11.92.1-2.0-1.92.1-2.0-1.92.1-1.60.8
Pavlov. Cond. lever contacts6.78.19.4-2.9-2.93.03.13.03.03.02.9-2.93.0-3.0-2.9-3.0-2.9-2.93.02.73.1-2.9-2.62.8-2.7-2.62.8-2.41.3
Pavlov. Cond. magazine entry number0.81.01.41.01.1-1.1-1.1-1.0-1.0-1.0-1.21.0-1.11.11.11.00.90.8-1.0-1.2-0.80.91.1-1.11.01.1-1.20.50.0
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.4-0.60.60.70.60.50.50.5-0.40.6-0.5-0.5-0.5-0.5-0.50.60.50.5-0.4-0.50.7-0.7-0.50.5-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.3.54.45.5-2.0-2.22.22.32.12.12.12.3-2.02.2-2.2-2.2-2.1-2.0-2.02.22.22.1-1.9-2.12.3-2.1-2.12.2-1.40.5
Pavlov. Cond. response bias4.45.46.3-2.4-2.42.52.52.42.52.52.4-2.42.5-2.5-2.5-2.5-2.4-2.32.42.32.3-2.3-2.32.3-2.2-2.22.4-1.90.9
Pavlov. Cond. lever latency2.53.55.31.92.2-2.0-2.2-1.9-1.7-1.7-2.01.8-2.12.02.11.71.51.3-2.0-2.2-1.51.32.2-2.32.22.2-2.20.50.6
Pavlov. Cond. magazine entry latency0.20.30.70.60.4-0.5-0.5-0.6-0.5-0.5-0.40.6-0.40.50.40.60.60.8-0.4-0.2-0.50.70.3-0.30.40.2-0.10.8-0.8
Pavlov. Cond. change in total contacts0.61.43.0-0.8-1.41.11.30.80.70.71.3-0.81.2-1.1-1.3-0.8-0.5-0.11.11.70.4-0.2-1.71.6-1.6-1.71.70.6-1.6
Pavlov. Cond. index score0.30.51.5-0.4-0.80.60.70.40.30.30.7-0.40.7-0.6-0.7-0.3-0.20.10.71.00.20.0-1.01.0-0.9-1.01.00.6-1.2
Pavlov. Cond. latency score0.40.61.7-0.5-0.90.70.90.50.40.40.9-0.50.8-0.7-0.9-0.4-0.20.10.81.20.3-0.0-1.11.1-1.0-1.21.10.6-1.3
Pavlov. Cond. lever contacts1.82.74.2-1.6-1.91.71.91.61.41.41.7-1.51.8-1.7-1.8-1.5-1.3-1.11.81.91.2-1.1-2.02.1-1.9-2.02.0-0.4-0.6
Pavlov. Cond. magazine entry number0.30.42.20.10.5-0.4-0.4-0.0-0.1-0.1-0.50.1-0.50.40.50.1-0.1-0.5-0.5-0.9-0.1-0.30.8-0.70.60.9-0.9-0.91.5
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.7-0.60.60.60.70.60.60.6-0.60.5-0.6-0.6-0.6-0.7-0.80.50.40.4-0.7-0.40.4-0.6-0.50.4-0.70.5
Pavlov. Cond. lever-magazine prob. diff.0.30.51.8-0.4-0.80.60.70.30.30.30.8-0.40.7-0.6-0.8-0.3-0.10.20.71.10.20.0-1.01.0-0.9-1.11.00.7-1.3
Pavlov. Cond. response bias0.91.32.5-1.0-1.31.11.30.90.90.91.2-0.91.3-1.1-1.3-0.9-0.7-0.41.21.50.7-0.5-1.51.5-1.4-1.51.60.2-1.0
Time in closed arm before self-admin0.30.61.00.50.9-1.0-0.7-0.7-1.0-1.0-0.70.7-1.00.80.80.80.70.7-0.9-0.8-0.80.70.7-0.60.80.4-0.60.6-0.3
Time in closed arm after self-admin0.30.31.70.50.1-0.2-0.2-0.8-0.4-0.40.00.7-0.10.30.20.50.70.9-0.10.1-0.60.8-0.20.10.0-0.30.21.1-1.3
Time in open arm before self-admin1.21.42.4-1.2-1.31.41.11.41.51.51.0-1.41.2-1.1-1.0-1.3-1.4-1.61.00.71.2-1.4-0.60.7-0.9-0.50.6-1.51.3
Time in open arm after self-admin0.80.92.3-1.1-0.70.80.81.41.01.00.5-1.20.7-0.8-0.7-1.0-1.2-1.50.70.31.3-1.3-0.20.4-0.5-0.40.3-1.51.5
Bone: periosteal estimation1.84.45.4-2.2-2.32.32.12.12.22.22.3-2.12.2-2.2-2.2-2.2-2.1-1.92.22.12.2-2.0-2.12.1-2.3-2.12.0-1.50.6
Bone: periosteal perimeter0.61.21.6-1.3-1.11.20.91.11.31.31.1-1.21.1-1.1-1.1-1.2-1.2-1.21.00.81.2-1.3-0.90.8-1.0-0.90.9-1.20.9
Bone: post-yield work2.23.75.4-2.1-1.92.01.92.22.12.11.8-2.11.9-2.0-1.9-2.1-2.2-2.31.81.61.9-2.2-1.61.6-1.6-1.51.6-2.11.6
Progressive ratio test 1 active lever presses0.61.02.80.61.0-0.8-1.1-0.6-0.6-0.6-1.60.7-0.70.91.10.60.40.4-0.4-1.60.30.21.7-1.41.71.7-0.9-0.61.4
Progressive ratio test 1 breakpoint0.50.82.40.50.9-0.6-1.0-0.5-0.4-0.4-1.40.6-0.60.80.90.50.30.3-0.3-1.50.40.11.5-1.31.51.5-0.7-0.61.3
Progressive ratio test 1 inactive lever presses0.41.14.8-1.2-0.60.80.51.21.11.10.2-1.20.7-0.8-0.6-1.1-1.3-1.40.80.11.5-1.5-0.0-0.00.10.10.1-2.02.2
Progressive ratio test 2 active lever presses1.01.44.30.71.2-1.1-1.3-0.7-0.9-0.9-1.70.8-1.01.11.30.80.50.4-0.6-2.00.20.32.1-1.71.81.7-1.1-0.51.4
Progressive ratio test 2 breakpoint1.21.54.40.81.2-1.1-1.3-0.7-1.0-1.0-1.70.9-1.11.21.40.80.60.4-0.7-2.00.20.32.1-1.71.81.8-1.2-0.51.5
Progressive ratio test 2 inactive lever presses0.00.10.7-0.3-0.30.20.10.30.10.1-0.1-0.30.2-0.1-0.1-0.2-0.3-0.40.5-0.30.8-0.40.5-0.10.10.10.3-0.60.7
Incentive Sensitization - Responses0.20.51.30.50.8-0.7-0.9-0.4-0.6-0.6-0.90.6-0.60.60.70.40.30.3-0.0-1.10.70.11.2-1.11.01.0-0.3-0.30.8
Incentive Sensitization - Breakpoint0.20.51.50.60.9-0.7-0.9-0.5-0.7-0.7-0.90.7-0.60.70.80.50.30.3-0.1-1.20.60.21.2-1.11.01.0-0.4-0.30.8
Sum of active levers in priming session hrs 5-63.53.35.71.72.2-1.8-2.1-1.6-1.3-1.3-2.21.5-1.91.92.01.61.41.1-2.1-2.2-1.31.22.3-2.32.32.3-2.40.40.8
Progressive ratio0.00.00.1-0.10.1-0.1-0.2-0.10.00.0-0.1-0.2-0.10.10.10.0-0.0-0.1-0.2-0.30.0-0.10.2-0.20.00.1-0.4-0.20.3
Food seeking constrained by brief footshock7.08.713.0-3.6-2.52.92.83.43.23.22.5-3.52.8-3.0-2.8-3.3-3.4-3.62.92.33.4-3.5-2.12.2-2.1-2.22.2-3.52.8
Seeking ratio, punishment vs. effort1.22.63.5-1.8-1.61.71.71.91.71.71.5-1.71.7-1.7-1.6-1.7-1.8-1.81.81.51.9-1.7-1.31.5-1.3-1.41.6-1.61.0
Retroperitoneal fat weight0.41.62.81.41.1-1.3-1.3-1.6-1.4-1.4-1.01.5-1.21.21.11.31.41.6-1.3-0.7-1.71.40.7-1.01.00.8-0.71.5-1.3
Reaction time number correct0.00.20.7-0.6-0.30.20.20.50.20.20.1-0.60.1-0.2-0.2-0.4-0.5-0.70.1-0.00.5-0.6-0.0-0.1-0.1-0.20.1-0.70.9
Reaction time mean minus median0.21.05.1-0.1-1.00.80.90.30.50.51.0-0.30.9-0.7-0.9-0.20.10.50.71.5-0.10.4-1.41.3-1.4-1.61.11.3-2.3
Reaction time mean minus median AUC0.21.43.3-0.8-1.41.21.30.90.90.91.3-0.91.3-1.1-1.3-0.7-0.5-0.21.21.60.5-0.2-1.61.6-1.7-1.81.40.6-1.6
Reaction time num false alarms0.00.10.5-0.1-0.40.10.40.2-0.2-0.20.20.10.2-0.1-0.2-0.00.10.10.30.30.10.2-0.30.5-0.6-0.20.20.5-0.7
Reaction time num false alarms AUC0.20.50.8-0.7-0.80.70.80.90.60.60.6-0.60.7-0.7-0.7-0.7-0.6-0.60.80.70.8-0.6-0.70.8-0.9-0.60.5-0.40.0
Reaction time trials correct on left0.00.20.7-0.6-0.30.20.20.50.20.20.1-0.60.1-0.2-0.2-0.4-0.5-0.70.1-0.00.5-0.6-0.0-0.1-0.1-0.20.1-0.70.9
Reaction time trials on left0.00.10.6-0.5-0.20.10.10.40.10.10.0-0.5-0.0-0.2-0.1-0.3-0.4-0.50.0-0.10.4-0.40.0-0.2-0.0-0.1-0.0-0.60.8
Reaction time mean0.81.86.51.70.9-1.0-1.1-1.6-1.3-1.3-0.71.6-0.91.10.91.51.72.1-1.0-0.3-1.61.90.3-0.50.50.3-0.62.4-2.6
Reaction time mean AUC0.92.27.41.81.0-1.2-1.1-1.8-1.4-1.4-0.91.7-1.01.31.01.61.92.2-1.1-0.4-1.72.10.4-0.50.60.4-0.72.6-2.7
Median of all reaction times2.23.55.82.21.7-1.8-1.9-2.2-1.9-1.9-1.52.2-1.71.81.72.12.22.4-1.7-1.2-2.02.31.2-1.41.41.3-1.42.4-2.1
Reaction time omissions1.52.43.51.81.7-1.5-1.6-1.7-1.3-1.3-1.51.8-1.61.61.61.71.71.6-1.9-1.4-1.91.61.3-1.51.51.5-1.61.4-0.8
Reaction time false alarm rate0.00.10.60.3-0.1-0.00.1-0.0-0.2-0.2-0.00.40.10.0-0.00.20.30.30.10.1-0.10.3-0.10.3-0.30.1-0.00.6-0.8
Reaction time premature initiation rate2.23.35.42.31.9-1.8-1.9-2.2-1.8-1.8-1.62.2-1.71.81.61.92.02.3-1.9-1.1-2.12.11.2-1.51.61.5-1.42.1-1.7
Reaction time premature initiations0.72.23.11.81.6-1.5-1.6-1.7-1.5-1.5-1.41.7-1.51.51.41.51.61.7-1.7-1.0-1.71.61.0-1.41.41.3-1.21.5-1.1
Std. dev. reaction times0.20.76.20.7-0.20.00.1-0.5-0.3-0.30.20.60.10.1-0.10.50.81.2-0.10.7-0.91.1-0.70.6-0.6-0.70.51.8-2.5
Reaction time trials completed0.00.10.6-0.5-0.20.10.10.40.10.10.0-0.5-0.0-0.2-0.1-0.3-0.4-0.50.0-0.10.4-0.40.0-0.2-0.0-0.1-0.0-0.60.8
Reaction time trials AUC0.00.10.6-0.5-0.20.10.10.40.10.10.1-0.5-0.0-0.2-0.1-0.3-0.4-0.5-0.0-0.10.3-0.40.0-0.2-0.0-0.1-0.0-0.60.8
Run reversals in cocaine runway, females0.10.20.6-0.3-0.4-0.20.40.1-0.5-0.50.3-0.3-0.1-0.0-0.10.10.20.2-0.00.4-0.70.3-0.30.5-0.4-0.80.00.5-0.7
Run reversals in cocaine runway, males0.10.10.20.40.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.30.30.30.30.30.3-0.2-0.2-0.10.30.2-0.20.20.3-0.30.3-0.2
Latency to leave start box in cocaine runway0.50.81.2-0.7-0.80.90.80.71.01.01.0-0.90.9-1.0-1.0-0.9-0.8-0.60.81.10.5-0.8-1.10.9-0.9-1.11.0-0.50.1
Latency to leave start box in cocaine runway, F0.10.10.30.20.4-0.3-0.4-0.3-0.1-0.1-0.20.1-0.40.20.30.10.10.1-0.5-0.3-0.4-0.00.3-0.50.50.3-0.5-0.30.5
Latency to leave start box in cocaine runway, M2.52.43.0-1.5-1.41.71.61.61.71.71.6-1.61.7-1.7-1.7-1.6-1.6-1.51.61.61.6-1.5-1.61.5-1.5-1.51.6-1.20.5
Std. dev. time between licks in bursts0.20.40.60.70.6-0.7-0.6-0.6-0.8-0.8-0.70.7-0.70.70.70.70.70.7-0.6-0.7-0.60.70.7-0.60.50.6-0.60.7-0.5
Total sessions with >9 infusions0.30.42.8-0.20.4-0.0-0.40.20.30.3-0.8-0.1-0.00.10.3-0.2-0.4-0.40.2-0.90.9-0.61.0-0.80.90.9-0.1-1.21.7
Short access day 1 total inactive lever presses0.51.03.8-1.1-0.40.90.41.01.31.30.4-1.00.8-0.8-0.7-1.1-1.3-1.30.80.21.4-1.4-0.30.10.0-0.10.6-1.81.9
Short access day 10 total inactive lever presses0.21.12.2-0.8-0.91.10.90.81.11.11.2-0.91.1-1.2-1.2-1.1-1.0-0.81.11.31.0-0.9-1.51.0-1.0-1.11.4-0.60.1
Short access day 1 total infusions0.30.63.9-0.40.20.2-0.30.30.60.6-0.7-0.30.2-0.00.1-0.4-0.6-0.60.4-0.81.1-0.80.9-0.80.90.8-0.0-1.52.0
Short access day 10 total infusions0.30.52.9-0.10.5-0.3-0.60.00.10.1-0.9-0.0-0.40.40.50.0-0.2-0.3-0.3-1.10.4-0.41.2-1.01.21.0-0.6-1.11.7
Short access total infusions0.60.83.50.20.8-0.5-0.9-0.2-0.2-0.2-1.30.3-0.50.60.80.2-0.1-0.1-0.2-1.40.6-0.31.5-1.31.51.4-0.6-1.11.9
Short access day 1 locomotion1.11.93.91.01.7-1.3-1.7-1.1-0.8-0.8-1.91.0-1.41.31.41.10.90.9-1.6-1.8-1.00.71.9-1.92.01.8-1.5-0.11.0
Short access day 10 total locomotion0.41.42.21.21.3-1.3-1.2-1.2-1.4-1.4-1.21.3-1.31.21.11.21.21.4-1.3-1.0-1.51.31.1-0.91.00.9-0.71.2-0.9
Short access total locomotion0.50.71.70.31.1-0.8-0.9-0.4-0.4-0.4-1.20.4-0.90.80.90.60.40.4-1.1-1.2-0.70.31.3-1.11.21.1-0.9-0.20.8
One hour access (0.3 mA shock)0.20.31.4-0.7-0.40.10.30.60.10.1-0.2-0.60.1-0.00.1-0.2-0.4-0.70.4-0.70.7-0.50.8-0.10.10.3-0.4-0.91.2
Compulsive drug intake0.20.30.9-0.4-0.80.30.70.40.00.00.9-0.50.3-0.5-0.5-0.3-0.2-0.20.30.8-0.3-0.1-0.70.8-0.9-0.70.60.3-0.7
One hour access (shock baseline)0.20.53.4-0.30.2-0.1-0.30.30.20.2-0.7-0.2-0.10.20.4-0.1-0.3-0.60.1-1.10.7-0.51.2-0.80.90.8-0.7-1.21.8
Social response proportion1.82.23.81.81.5-1.5-1.4-1.7-1.6-1.6-1.11.7-1.61.51.41.61.71.7-1.7-1.0-1.91.70.9-1.11.01.1-1.11.8-1.4
Social responses0.81.01.5-1.0-1.00.91.11.10.90.91.2-1.00.9-1.1-1.1-1.0-1.0-1.00.91.20.9-1.0-1.21.0-1.1-1.11.0-0.70.3
Social time0.00.00.00.20.2-0.1-0.2-0.2-0.0-0.00.00.2-0.10.10.10.10.10.0-0.1-0.20.20.00.1-0.20.20.2-0.1-0.00.1
Soleus weight0.30.86.6-0.60.20.2-0.30.50.80.8-0.4-0.5-0.1-0.10.2-0.5-0.8-1.1-0.2-0.80.7-1.00.8-0.90.70.9-0.8-1.92.6
Bone: stiffness4.37.99.6-2.9-3.13.12.92.72.92.93.0-2.83.1-3.0-3.0-2.9-2.7-2.33.03.02.8-2.6-2.92.9-3.0-2.93.0-1.80.5
Tibialis anterior weight8.428.935.3-5.9-5.55.85.35.55.95.95.3-5.95.6-5.6-5.5-5.7-5.7-5.65.55.05.8-5.7-4.94.6-4.8-4.94.8-5.03.1
Time to tail flick, vehicle, before self-admin0.60.83.50.70.5-0.9-0.6-0.8-1.1-1.1-0.70.7-0.90.90.81.01.00.8-1.0-0.8-1.91.00.7-0.40.50.1-0.81.0-0.9
Time to tail flick, vehicle, after self-admin0.00.00.10.1-0.30.20.1-0.00.00.00.10.10.2-0.1-0.2-0.1-0.00.20.20.3-0.20.0-0.30.2-0.2-0.00.20.2-0.3
Time to tail flick, test, before self-admin0.40.40.7-0.8-0.70.50.80.80.30.30.7-0.80.6-0.6-0.6-0.6-0.6-0.70.80.40.8-0.6-0.30.8-0.9-0.60.8-0.40.1
Time to tail flick, test, after self-admin2.12.25.0-1.5-1.81.31.81.20.90.91.9-1.51.4-1.5-1.6-1.2-1.1-0.81.31.80.5-0.9-1.82.0-2.2-2.21.8-0.1-0.9
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.2-0.50.60.40.40.60.60.5-0.20.6-0.6-0.6-0.6-0.5-0.40.80.71.0-0.5-0.60.4-0.4-0.10.7-0.40.2
Delta time to tail flick, test, before/after SA0.10.10.90.2-0.1-0.10.1-0.3-0.2-0.20.20.2-0.1-0.0-0.10.10.30.5-0.20.5-0.70.4-0.60.3-0.3-0.50.20.7-0.9
Tibia length0.10.32.8-0.7-0.10.2-0.30.20.50.50.0-0.60.1-0.2-0.1-0.5-0.7-0.80.0-0.20.4-0.80.2-0.60.30.3-0.3-1.31.7
Ambulatory time before self-admin1.34.17.5-2.1-1.72.41.72.12.72.71.7-2.12.2-2.0-1.9-2.2-2.3-2.22.01.52.4-2.3-1.51.3-1.3-1.11.7-2.31.9
Ambulatory time after self-admin0.50.82.1-0.8-0.71.10.70.81.21.20.9-0.71.1-0.9-0.9-0.9-0.9-0.81.20.81.4-0.9-0.80.7-0.7-0.61.2-0.80.5
Bone: tissue strength0.20.20.3-0.4-0.50.50.40.40.40.40.6-0.40.5-0.5-0.5-0.4-0.4-0.40.40.50.3-0.4-0.60.5-0.5-0.50.6-0.2-0.0
Total heroin consumption1.41.73.81.01.6-1.1-1.6-1.0-0.6-0.6-1.80.9-1.21.31.41.00.70.7-1.4-1.7-0.50.51.7-1.91.91.9-1.7-0.31.3
Bone: trabecular number0.91.73.4-1.2-1.51.41.61.31.11.11.4-1.21.4-1.3-1.4-1.1-1.0-0.81.31.60.8-0.9-1.51.8-1.7-1.61.6-0.3-0.5
Bone: trabecular spacing0.00.00.20.20.00.0-0.0-0.2-0.0-0.00.20.10.1-0.1-0.10.00.10.20.10.20.00.1-0.30.1-0.1-0.20.30.3-0.5
Bone: trabecular thickness0.20.20.60.50.3-0.4-0.1-0.4-0.6-0.6-0.40.6-0.40.50.40.50.60.6-0.4-0.3-0.70.60.3-0.10.10.3-0.20.7-0.7
Bone: trabecular tissue density2.95.05.9-2.4-2.32.42.32.22.42.42.2-2.42.4-2.4-2.4-2.4-2.3-2.22.42.32.3-2.3-2.22.0-2.0-2.22.3-1.91.0
Water consumed over 24 hours0.61.11.9-1.0-1.01.11.00.91.01.01.2-1.01.1-1.1-1.1-1.1-1.0-0.81.31.11.4-0.9-1.11.0-1.1-1.11.2-0.60.1
Number of responses in last shaping day0.81.07.2-0.10.9-0.3-0.80.10.50.5-1.1-0.0-0.50.30.5-0.2-0.5-0.7-0.8-1.10.2-0.81.2-1.41.51.5-1.0-1.82.7