Hub : Genes

Atosb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Atosb 0.03 0.03 5.6e-03 0.02 0.02 0.02 0.02 5.3e-03 5.9e-03 1.1e-02 8.9e-03
2 IC mRNA stability Atosb 0.11 0.09 3.2e-03 0.03 0.03 0.01 0.03 2.0e-02 2.2e-02 1.6e-01 1.8e-02
3 Brain alternative TSS XM_039109529.1 0.04 0.03 8.6e-04 0.03 0.01 0.03 0.03 6.6e-04 1.8e-02 4.8e-04 1.3e-03
4 Brain intron excision ratio chr5_62061114_62064183 0.06 0.04 4.8e-05 0.04 0.02 0.04 0.02 1.5e-04 8.0e-03 4.5e-05 9.4e-03
5 PL isoform ratio XM_039109529.1 0.02 0.02 6.1e-03 0.02 0.02 0.02 0.02 2.9e-03 4.6e-03 6.0e-03 5.0e-03
6 BLA alternative TSS XM_039109529.1 0.08 0.06 2.9e-03 0.03 0.03 0.03 0.03 9.1e-03 1.6e-02 1.1e-02 1.0e-02
7 PL intron excision ratio chr5_62061114_62064183 0.03 0.02 2.3e-03 0.02 0.02 0.01 0.01 2.6e-03 4.4e-03 9.9e-03 9.3e-03
8 Liver gene expression Atosb 0.18 0.1 0.0e+00 0.15 0.17 0.16 0.15 9.5e-17 2.8e-18 6.0e-17 9.6e-17
9 Brain isoform ratio NM_001013931.2 0.03 0.03 7.2e-03 0.03 0.02 0.03 0.03 1.4e-03 5.4e-03 2.2e-03 1.6e-03
10 Brain alternative TSS XM_039109529.1 0.04 0.03 5.7e-04 0.03 0.01 0.04 0.03 7.0e-04 1.4e-02 3.1e-04 2.1e-03
11 pVTA alternative TSS XM_039109529.1 0.06 0.04 1.7e-05 0.04 0.05 0.04 0.04 3.7e-04 1.3e-04 3.5e-04 5.0e-04
12 pVTA isoform ratio XM_039109529.1 0.06 0.04 3.5e-05 0.03 0.04 0.04 0.03 1.4e-03 4.4e-04 6.3e-04 9.6e-04
13 pVTA alternative TSS XM_039109529.1 0.05 0.04 1.3e-04 0.03 0.04 0.03 0.03 2.8e-03 8.1e-04 1.6e-03 2.9e-03
14 IL alternative TSS XM_039109528.2 0.14 0.1 6.1e-03 0.06 0.06 0.05 0.06 1.6e-02 1.4e-02 2.7e-02 1.3e-02
15 Brain isoform ratio XM_039109529.1 0.05 0.04 3.3e-04 0.03 0.01 0.04 0.02 6.2e-04 2.5e-02 2.0e-04 3.1e-03
16 Adipose mRNA stability Atosb 0.11 0.07 1.6e-11 0.1 0.1 0.1 0.1 2.4e-11 3.1e-11 1.2e-10 2.5e-11
17 pVTA intron excision ratio chr5_62061114_62064183 0.07 0.06 6.1e-05 0.04 0.03 0.04 0.04 1.5e-04 9.9e-04 7.9e-04 7.4e-04
18 NAcc gene expression Atosb 0.04 0.03 1.1e-07 0.05 0.02 0.04 0 1.1e-07 7.0e-04 2.2e-07 8.5e-02
19 Adipose gene expression Atosb 0.23 0.15 0.0e+00 0.19 0.19 0.2 0.2 1.2e-20 1.1e-20 2.9e-21 1.4e-21
20 Liver alternative TSS XM_039109528.2 0.03 0.02 7.4e-04 0.04 0.03 0.03 0.03 2.8e-05 2.2e-04 1.6e-04 2.6e-04
21 Brain gene expression Atosb 0.05 0.04 5.7e-04 0.03 0.02 0.01 0.01 9.6e-04 5.5e-03 2.6e-02 6.6e-02
22 Liver alternative TSS XM_063287372.1 0.05 0.03 1.5e-05 0.06 0.04 0.05 0.05 4.9e-07 1.6e-05 1.5e-06 2.7e-06
23 PL alternative TSS XM_039109529.1 0.03 0.02 4.0e-03 0 0.01 0.01 0 9.8e-02 1.6e-02 4.5e-02 8.0e-02
24 BLA isoform ratio XM_039109530.1 0.08 0.06 8.8e-03 0.01 0.02 0.01 0.01 1.3e-01 4.8e-02 8.1e-02 1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.32.23.61.4-1.7-1.6-1.7-1.5-1.3-1.31.51.4-1.6-1.5-1.6-1.3-1.0-1.5-1.8-1.01.71.91.91.8-1.8-0.4-0.4
Area under the delay curve0.60.81.4-0.71.10.91.00.60.60.6-1.0-0.71.00.80.90.70.41.21.20.8-1.0-1.1-1.0-1.10.90.10.4
BMI with tail1.55.37.12.2-2.5-2.4-2.5-2.2-2.3-2.32.52.3-2.4-2.5-2.5-2.3-1.9-2.3-2.6-1.92.72.42.42.6-2.4-1.40.3
BMI without tail2.36.98.82.7-2.9-2.8-2.7-2.5-2.7-2.72.82.7-2.8-2.8-2.9-2.7-2.3-2.6-2.9-2.33.02.52.72.8-2.6-1.90.7
Body weight3.214.117.84.2-4.0-4.0-3.9-4.1-4.1-4.13.74.0-3.9-4.0-3.9-4.1-4.0-3.7-3.4-3.73.53.43.43.4-3.2-3.62.3
Weight adjusted by age0.10.20.70.3-0.4-0.4-0.4-0.7-0.5-0.50.40.5-0.3-0.3-0.3-0.5-0.8-0.2-0.2-0.10.10.20.00.10.2-0.80.9
Bone surface0.81.51.91.4-1.4-1.3-1.4-1.4-1.2-1.21.21.3-1.3-1.3-1.3-1.2-1.2-1.2-1.3-1.11.21.41.41.3-1.2-0.90.4
Bone volume0.71.21.91.1-1.3-1.2-1.2-1.1-1.0-1.01.11.1-1.2-1.1-1.2-1.0-0.8-1.1-1.3-0.81.21.41.31.3-1.3-0.5-0.1
Breakpoint value in progressive ratio session1.51.86.2-0.31.10.61.30.4-0.1-0.1-1.6-0.21.01.01.20.5-0.21.31.90.0-1.9-2.0-2.0-1.92.0-1.32.5
Number of licking bursts3.96.37.92.4-2.6-2.7-2.6-2.3-2.5-2.52.82.5-2.7-2.7-2.7-2.6-2.1-2.8-2.7-2.72.72.62.62.6-2.8-1.60.4
Context. condit. distance diff. score0.10.10.2-0.50.30.40.30.40.40.4-0.3-0.50.30.40.30.40.50.20.20.3-0.2-0.2-0.3-0.30.30.5-0.4
Locomotion velocity, session 11.21.311.01.1-0.1-0.6-0.3-1.2-1.1-1.1-0.01.1-0.3-0.5-0.2-1.0-1.9-0.20.3-1.1-0.3-0.4-0.5-0.40.6-2.63.3
Locomotion distance, session 10.50.63.60.8-0.3-0.5-0.3-0.9-0.9-0.90.30.9-0.4-0.6-0.4-0.8-1.3-0.3-0.1-0.70.1-0.1-0.10.0-0.1-1.61.9
Locomotion velocity, session 22.42.83.91.5-1.9-1.8-1.9-1.7-1.5-1.51.91.5-1.8-1.7-1.8-1.6-1.4-1.7-1.9-1.31.92.02.01.8-1.8-0.8-0.1
Locomotion distance, session 22.33.24.72.1-1.7-1.8-1.6-1.9-2.0-2.01.72.1-1.7-1.9-1.8-2.0-2.1-1.6-1.5-1.81.51.21.31.5-1.6-2.21.7
Locomotion velocity, session 30.20.32.30.40.1-0.20.1-0.4-0.5-0.5-0.20.4-0.1-0.2-0.0-0.4-0.8-0.10.2-0.5-0.3-0.4-0.3-0.30.4-1.21.5
Locomotion distance, session 32.22.43.81.8-1.5-1.7-1.4-1.8-1.8-1.81.41.8-1.5-1.6-1.5-1.8-1.9-1.4-1.2-1.61.21.11.21.2-1.1-2.01.6
Stereotopy head waving bouts, day 30.30.31.7-0.10.60.30.40.10.10.1-0.7-0.10.40.40.50.1-0.20.40.7-0.1-0.7-0.6-0.8-0.80.9-0.81.3
Stereotopy head waving duration, day 30.30.40.9-0.50.70.60.60.50.50.5-0.8-0.50.60.60.70.50.30.50.70.2-0.8-0.7-0.9-0.80.9-0.10.5
Locomotion velocity, session 70.10.10.1-0.30.30.30.40.30.30.3-0.3-0.30.30.30.30.30.30.30.20.3-0.2-0.3-0.3-0.30.30.2-0.1
Locomotion distance, session 70.20.30.70.7-0.5-0.5-0.4-0.5-0.6-0.60.40.7-0.4-0.5-0.5-0.6-0.7-0.4-0.4-0.50.30.30.30.4-0.4-0.80.8
Stereotopy head waving bouts, day 71.11.32.01.2-1.1-1.2-1.2-1.3-1.3-1.30.91.3-1.2-1.1-1.1-1.2-1.3-1.3-0.9-1.40.91.00.90.9-0.6-1.31.1
Stereotopy head waving duration, day 70.60.71.20.9-0.8-0.9-0.9-0.9-0.9-0.90.60.9-0.9-0.8-0.8-0.9-0.9-1.0-0.7-1.10.70.80.70.6-0.4-0.90.7
Locomotion velocity, session 80.10.21.50.30.0-0.10.1-0.2-0.3-0.3-0.00.3-0.0-0.10.0-0.3-0.6-0.10.1-0.6-0.2-0.3-0.2-0.20.3-0.91.2
Locomotion distance, session 80.20.41.60.7-0.3-0.5-0.3-0.6-0.7-0.70.30.7-0.4-0.5-0.4-0.7-0.9-0.4-0.3-0.70.30.10.10.1-0.3-1.11.2
Degree of sensitization distance1.11.11.4-1.21.11.11.11.21.21.2-1.1-1.11.11.11.11.11.21.01.01.1-1.0-0.9-0.9-1.00.81.0-0.7
Degree of sensitization stereotypy1.31.41.81.2-1.2-1.3-1.3-1.2-1.3-1.31.11.2-1.3-1.2-1.2-1.2-1.1-1.4-1.1-1.31.11.21.21.1-1.0-1.00.5
Conditioned locomotion0.10.21.00.00.40.10.40.1-0.2-0.2-0.40.00.20.20.2-0.0-0.20.20.5-0.3-0.4-0.6-0.6-0.50.3-0.71.0
Cocaine response after cond. corrected1.82.23.7-1.21.71.51.71.41.11.1-1.6-1.11.61.51.61.20.81.61.81.0-1.9-1.9-1.8-1.81.7-0.11.2
Cocaine response after cond. not corrected1.51.83.1-1.01.51.31.51.20.90.9-1.5-0.91.41.31.40.90.51.41.70.9-1.7-1.8-1.7-1.71.6-0.41.4
Cocaine response before conditioning0.81.01.21.0-1.1-1.0-1.0-1.0-1.0-1.01.01.1-1.1-1.0-1.1-1.0-0.8-1.0-1.1-0.91.11.01.11.1-1.0-0.60.1
Saline control response1.01.33.11.3-0.8-1.1-0.8-1.2-1.3-1.30.81.3-1.1-1.1-0.9-1.3-1.5-1.1-0.6-1.60.60.50.60.6-0.6-1.81.7
Bone: connectivity density0.61.02.10.8-1.2-1.0-1.3-1.0-0.7-0.71.00.8-1.0-1.0-1.0-0.8-0.5-1.0-1.2-0.41.21.41.31.2-1.20.1-0.7
Bone: cortical apparent density0.20.32.1-0.3-0.2-0.1-0.20.40.20.20.3-0.1-0.2-0.1-0.20.20.6-0.3-0.70.00.70.50.40.6-0.51.0-1.4
Bone: cortical area2.84.46.42.0-2.4-2.2-2.0-1.7-2.0-2.02.41.9-2.3-2.2-2.3-1.9-1.2-2.2-2.5-1.82.52.22.52.5-2.5-0.6-0.6
Bone: cortical porosity0.20.30.4-0.50.40.60.40.40.60.6-0.5-0.60.50.50.50.60.50.50.50.6-0.5-0.3-0.3-0.50.40.6-0.4
Bone: cortical porosity0.00.00.1-0.00.00.1-0.0-0.10.10.1-0.1-0.10.10.10.10.0-0.1-0.00.2-0.0-0.2-0.00.0-0.20.1-0.00.1
Bone: cortical thickness1.01.73.51.0-1.4-1.3-1.1-0.5-1.0-1.01.50.9-1.4-1.2-1.4-0.90.0-1.3-1.9-0.81.81.41.61.8-1.90.4-1.5
Bone: cortical thickness0.30.31.5-0.50.30.40.50.80.50.5-0.3-0.50.30.40.30.61.10.4-0.10.60.1-0.2-0.20.0-0.01.1-1.2
Bone: cortical tissue density0.20.21.8-0.3-0.10.0-0.10.50.20.20.2-0.2-0.10.0-0.10.20.7-0.2-0.60.10.60.40.30.5-0.41.0-1.3
Condit. Reinf. active minus inactive responses0.60.61.10.6-0.8-0.8-1.0-0.8-0.8-0.81.00.7-0.8-0.8-0.9-0.8-0.7-0.8-0.9-0.70.91.00.90.8-0.9-0.4-0.0
Condit. Reinf. active-inactive response ratio0.60.61.0-1.00.80.80.81.00.90.9-0.7-0.90.80.80.80.90.90.80.60.8-0.6-0.6-0.8-0.60.70.9-0.7
Condit. Reinf. active responses3.13.85.31.7-2.1-2.1-2.3-2.0-1.9-1.92.21.8-2.1-2.0-2.1-1.9-1.8-2.1-2.1-1.82.12.32.12.0-2.1-1.10.2
Condit. Reinf. inactive responses3.84.66.12.0-2.4-2.2-2.5-2.2-2.0-2.02.52.0-2.2-2.3-2.3-2.1-1.8-2.2-2.4-1.82.42.52.42.4-2.3-1.1-0.0
Incentive salience index mean4.75.87.22.3-2.5-2.6-2.7-2.6-2.5-2.52.62.4-2.5-2.5-2.5-2.5-2.5-2.5-2.3-2.52.32.52.42.2-2.4-1.91.0
Condit. Reinf. lever presses10.815.218.94.0-3.9-4.1-4.2-4.3-4.1-4.14.04.1-4.0-4.1-4.0-4.2-4.3-4.0-3.5-4.23.53.73.63.4-3.6-3.72.4
Condit. Reinf. active minus inactive responses0.70.91.31.1-1.1-1.0-1.0-0.9-0.9-0.91.01.0-1.0-1.0-1.0-0.9-0.7-1.0-1.1-0.81.01.01.01.1-1.1-0.4-0.1
Condit. Reinf. active-inactive response ratio0.10.10.30.4-0.5-0.3-0.3-0.2-0.2-0.20.50.2-0.3-0.3-0.4-0.2-0.1-0.3-0.5-0.00.40.40.50.5-0.50.2-0.5
Condit. Reinf. active responses2.43.34.32.1-2.0-1.9-1.9-1.9-1.9-1.91.81.9-1.9-1.9-1.9-1.8-1.7-1.8-1.9-1.51.81.81.71.9-2.0-1.20.4
Condit. Reinf. inactive responses3.03.85.12.0-2.1-2.1-2.1-2.0-2.0-2.01.92.0-2.2-2.1-2.1-1.9-1.5-2.1-2.1-1.82.22.11.92.2-2.3-1.0-0.0
Condit. Reinf. lever presses2.83.95.91.9-2.3-2.1-2.2-1.8-1.7-1.72.11.8-2.2-2.0-2.2-1.8-1.2-2.1-2.3-1.62.32.42.22.4-2.4-0.5-0.7
Condit. Reinf. lever reinforcers received2.83.85.02.2-2.2-2.1-2.1-2.1-2.0-2.02.02.1-2.1-2.1-2.1-2.0-1.8-2.0-2.0-1.72.02.01.92.1-2.1-1.30.4
Conditioned reinforcement - actives0.10.10.40.10.00.10.1-0.10.20.2-0.3-0.20.00.20.20.00.0-0.40.5-0.7-0.6-0.2-0.3-0.4-0.3-0.30.4
Conditioned reinforcement - inactives0.30.51.0-0.50.90.70.90.70.70.7-0.9-0.60.60.70.70.50.60.20.9-0.2-1.0-1.0-1.0-0.70.30.00.4
Conditioned locomotion0.10.10.90.30.30.10.1-0.3-0.1-0.1-0.30.00.20.00.1-0.2-0.30.10.5-0.2-0.5-0.3-0.3-0.4-0.1-0.70.9
Patch foraging indifference point 0 sec0.40.86.70.9-0.0-0.3-0.1-0.9-0.7-0.7-0.10.8-0.1-0.3-0.1-0.7-1.5-0.00.5-0.8-0.5-0.5-0.5-0.50.6-2.02.6
Patch foraging indifference point AUC7.711.214.73.7-3.7-3.5-3.7-3.8-3.5-3.53.53.6-3.4-3.5-3.4-3.5-3.7-3.2-2.9-2.92.93.33.33.2-3.0-2.91.7
Delay disc. indifference point, 0s delay1.11.22.2-1.01.21.11.10.80.90.9-1.3-1.01.21.11.21.00.61.21.50.8-1.3-1.3-1.4-1.51.30.20.4
Delay disc. indifference point, 16s delay1.21.42.8-0.81.51.01.40.80.50.5-1.4-0.81.11.11.20.90.41.31.60.4-1.5-1.6-1.7-1.61.4-0.21.0
Delay disc. indifference point, 2s delay0.10.10.30.0-0.1-0.1-0.2-0.1-0.0-0.00.20.0-0.2-0.2-0.2-0.10.1-0.2-0.2-0.10.30.40.40.3-0.40.3-0.5
Delay disc. indifference point, 24s delay0.10.10.2-0.40.30.20.30.40.10.1-0.3-0.40.30.30.30.40.30.50.30.4-0.2-0.3-0.3-0.30.30.3-0.2
Delay disc. indifference point, 4s delay0.10.10.5-0.30.50.40.30.20.30.3-0.4-0.30.50.30.30.30.20.70.50.6-0.4-0.4-0.3-0.40.30.10.1
Delay disc. indifference point, 8s delay0.00.00.10.10.00.0-0.1-0.1-0.0-0.00.10.10.1-0.1-0.1-0.1-0.10.2-0.00.30.10.10.20.1-0.2-0.10.1
Indifference point function ln k2.44.15.4-2.22.32.12.32.32.02.0-2.2-2.22.12.12.12.12.12.01.91.7-1.9-2.2-2.1-2.11.81.5-0.7
Indifference point function log k2.44.15.4-2.22.32.12.32.32.02.0-2.2-2.22.12.12.12.12.12.01.91.7-1.9-2.2-2.1-2.11.81.5-0.7
Patch foraging total patch changes 0 sec0.61.16.61.3-0.5-0.7-0.5-1.3-1.1-1.10.31.2-0.5-0.7-0.5-1.1-1.8-0.50.1-1.2-0.1-0.1-0.0-0.10.1-2.22.6
Patch foraging total patch changes 12 sec2.02.63.31.7-1.8-1.7-1.8-1.8-1.7-1.71.71.7-1.7-1.7-1.6-1.7-1.8-1.7-1.4-1.61.31.61.61.5-1.5-1.30.7
Patch foraging total patch changes 18 sec0.71.02.01.3-1.1-1.0-1.1-1.3-1.1-1.11.11.2-0.9-1.0-0.9-1.1-1.4-0.8-0.7-0.80.60.80.80.8-0.6-1.21.0
Patch foraging total patch changes 24 sec1.83.05.32.1-1.9-1.8-1.9-2.1-1.8-1.81.72.0-1.7-1.8-1.6-1.9-2.3-1.7-1.2-1.71.21.51.61.4-1.3-1.91.5
Patch foraging total patch changes 6 sec2.43.77.12.3-1.8-1.9-1.8-2.3-2.2-2.21.72.3-1.8-1.9-1.7-2.2-2.7-1.7-1.2-2.01.11.31.41.3-1.1-2.62.4
Patch foraging time to switch 0 sec2.04.16.8-2.52.12.02.22.52.12.1-2.0-2.51.92.11.92.22.61.91.61.9-1.7-1.8-1.7-1.81.42.2-1.7
Patch foraging water rate 0 sec1.22.54.52.0-1.5-1.5-1.5-1.9-1.7-1.71.41.9-1.4-1.6-1.5-1.8-2.1-1.3-1.2-1.61.31.11.01.2-1.0-2.01.8
Patch foraging water rate 12 sec0.00.00.40.20.1-0.10.20.0-0.2-0.2-0.10.3-0.0-0.00.0-0.1-0.20.00.1-0.1-0.0-0.3-0.1-0.00.1-0.50.6
Patch foraging water rate 18 sec0.30.40.90.5-0.7-0.7-0.6-0.4-0.5-0.50.60.6-0.8-0.6-0.7-0.5-0.1-0.9-0.8-0.71.00.70.80.9-1.00.1-0.6
Patch foraging water rate 24 sec0.10.21.8-0.3-0.10.10.00.40.40.40.1-0.3-0.00.1-0.00.30.6-0.1-0.30.40.40.20.30.3-0.41.0-1.3
Patch foraging water rate 6 sec0.71.11.71.1-0.9-1.1-0.8-0.9-1.0-1.00.91.1-1.1-1.1-1.1-1.1-0.8-1.2-1.1-1.31.20.80.90.9-1.3-0.90.5
Seeking ratio, delayed vs. immediate footshock3.34.05.31.9-2.0-2.3-2.1-1.9-2.3-2.32.12.0-2.3-2.1-2.2-2.1-1.7-2.1-2.1-1.72.22.01.92.1-2.1-1.40.5
Distance traveled before self-admin4.15.39.62.4-2.0-2.7-2.0-2.4-3.1-3.12.02.4-2.6-2.4-2.3-2.5-2.4-2.3-1.9-2.91.91.71.61.5-2.0-2.51.9
Distance traveled after self-admin1.72.14.51.1-1.2-1.6-1.3-1.0-1.5-1.51.51.1-1.7-1.5-1.6-1.4-0.7-1.8-1.7-1.91.71.51.41.4-2.1-0.6-0.2
Extensor digitorum longus weight5.120.224.44.8-4.7-4.9-4.7-4.6-4.9-4.94.64.7-4.8-4.7-4.7-4.7-4.5-4.7-4.4-4.94.24.14.24.3-4.2-3.72.0
Bone: elastic displacement5.96.910.0-2.82.52.82.62.92.92.9-2.4-2.82.72.72.62.92.82.82.23.2-2.2-2.4-2.2-2.12.42.8-2.0
Bone: elastic work2.43.19.4-2.01.31.71.52.22.02.0-1.1-2.01.51.61.42.02.61.50.62.1-0.7-0.9-0.9-0.70.93.0-3.1
Bone: endosteal estimation1.32.94.31.9-1.7-1.8-1.7-2.0-1.9-1.91.71.8-1.7-1.7-1.6-1.9-2.1-1.7-1.2-1.91.21.51.61.3-1.1-2.01.6
Bone: endosteal perimeter1.32.74.41.9-1.6-1.7-1.5-1.9-1.9-1.91.61.8-1.6-1.7-1.5-1.9-2.1-1.5-1.1-1.81.21.21.41.2-1.2-2.11.8
Epididymis fat weight0.41.32.01.0-1.4-1.2-1.4-1.1-1.1-1.11.41.0-1.2-1.2-1.3-1.1-1.0-1.1-1.3-0.71.41.41.41.3-1.2-0.5-0.1
Delta time in closed arm before/after self-admin0.70.61.40.4-0.9-0.8-0.8-0.2-0.6-0.61.00.4-0.9-0.7-0.8-0.5-0.0-0.8-1.2-0.31.21.01.01.0-0.90.3-0.9
Delta time in open arm before/after self-admin0.40.40.9-0.30.80.70.70.30.50.5-0.8-0.40.70.60.70.50.10.51.0-0.2-1.0-0.9-0.8-0.80.8-0.20.7
Diff in mean of infusions in LGA sessions0.10.10.7-0.4-0.00.20.10.50.30.3-0.0-0.40.10.20.10.30.70.0-0.10.00.20.00.10.2-0.10.7-0.8
Delay discount exponential model param0.50.61.30.6-1.0-0.8-0.9-0.5-0.5-0.50.90.6-0.9-0.7-0.8-0.6-0.3-1.1-1.1-0.80.91.00.91.0-0.8-0.0-0.4
Extinction: sum of active levers before priming3.53.86.0-2.12.41.92.32.01.51.5-2.3-1.91.92.12.11.91.82.02.20.9-2.2-2.3-2.3-2.22.01.0-0.0
Active lever presses in extinction session 60.40.40.7-0.50.60.40.70.60.20.2-0.7-0.50.50.70.70.60.60.70.80.4-0.8-0.7-0.6-0.60.80.30.0
Bone: final force2.03.24.01.9-2.0-1.9-1.7-1.6-1.8-1.82.01.8-1.9-1.9-1.9-1.8-1.4-1.9-1.9-1.81.91.81.91.9-1.9-1.10.2
Bone: final moment1.62.63.51.7-1.9-1.7-1.5-1.4-1.6-1.61.81.5-1.8-1.7-1.8-1.6-1.1-1.7-1.8-1.51.81.71.81.8-1.8-0.8-0.1
Food consumed during 24 hour testing period0.91.21.71.2-1.0-1.1-0.9-1.0-1.2-1.21.11.2-1.1-1.1-1.1-1.2-1.1-1.1-1.0-1.31.00.80.91.0-1.0-1.20.9
Glucose2.64.15.32.3-2.2-2.1-2.2-2.2-2.1-2.12.12.3-2.0-2.1-2.1-2.2-2.1-2.0-2.0-2.02.01.91.92.0-1.8-1.81.0
Heart weight0.71.11.71.2-1.2-1.2-1.1-1.0-1.3-1.31.11.3-1.1-1.1-1.1-1.0-0.9-0.9-1.1-0.81.11.01.21.2-0.8-0.70.3
Delay discount hyperbolic model param0.40.40.90.4-0.9-0.7-0.7-0.4-0.4-0.40.70.4-0.8-0.6-0.6-0.5-0.2-1.0-0.9-0.60.70.80.70.8-0.60.1-0.5
Intermittent access intake day 1-15 change0.51.11.90.7-1.1-1.2-1.1-0.9-1.0-1.01.20.5-1.2-1.1-1.2-1.0-0.7-1.2-1.3-0.71.41.21.21.0-1.2-0.4-0.2
Intermittent access intake escalation0.50.91.90.6-1.1-1.1-1.0-0.7-0.9-0.91.20.4-1.1-1.0-1.1-0.9-0.5-1.1-1.3-0.61.41.21.21.0-1.2-0.2-0.4
Intermittent access intake escalation 21.41.53.20.6-1.3-1.3-1.3-0.7-0.9-0.91.40.5-1.5-1.2-1.4-1.0-0.4-1.6-1.6-1.01.81.51.51.5-1.80.1-1.0
Intermitt. access day 1 inactive lever presses0.51.72.71.4-1.2-1.4-1.2-1.4-1.6-1.61.41.4-1.3-1.4-1.4-1.5-1.4-1.1-1.4-1.31.41.11.01.2-1.0-1.40.9
Intermitt. access day 15 inactive lever presses0.10.10.30.0-0.2-0.4-0.0-0.1-0.5-0.50.2-0.0-0.4-0.3-0.3-0.4-0.2-0.3-0.3-0.50.4-0.1-0.1-0.0-0.1-0.50.5
Intermitt. access escalation Index0.50.61.20.8-0.7-0.9-0.8-1.0-1.1-1.10.60.9-0.8-0.9-0.8-0.9-0.9-0.6-0.6-0.70.90.60.60.5-0.3-1.00.7
Intermittent access day 1 total infusions1.82.95.8-1.31.71.71.71.21.51.5-2.2-1.41.71.71.91.51.01.62.40.9-2.3-2.0-2.2-2.21.90.20.9
Intermittent access day 15 total infusions0.00.00.1-0.1-0.1-0.0-0.00.00.10.1-0.1-0.3-0.10.00.00.00.1-0.20.2-0.2-0.20.0-0.1-0.2-0.1-0.00.0
Intermittent access terminal intake (last 3 days)0.10.10.80.0-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.3-0.1-0.1-0.2-0.0-0.70.2-0.9-0.1-0.0-0.1-0.2-0.5-0.30.4
Intermittent access total infusions0.10.10.50.10.10.10.1-0.10.20.2-0.4-0.10.00.10.2-0.0-0.1-0.30.6-0.7-0.6-0.3-0.4-0.4-0.1-0.50.7
Intermittent access day 1 locomotion1.92.44.4-1.01.71.71.51.01.41.4-1.9-1.11.71.61.71.30.81.72.11.2-2.1-1.8-1.9-1.91.80.20.7
Intermittent access day 15 total locomotion1.01.83.2-0.91.31.51.41.11.41.4-1.6-1.21.51.41.51.20.91.41.71.2-1.8-1.6-1.6-1.51.60.40.4
Intermittent access total locomotion1.92.23.2-1.31.51.71.51.41.81.8-1.7-1.51.61.61.61.51.41.31.71.3-1.7-1.4-1.5-1.61.31.0-0.4
Intermittent access standard deviation0.20.30.70.5-0.4-0.6-0.4-0.4-0.7-0.70.50.4-0.6-0.6-0.6-0.7-0.5-0.6-0.6-0.70.50.30.30.4-0.8-0.70.5
Left kidney weight0.62.84.92.1-1.6-1.7-1.4-1.8-2.0-2.01.52.0-1.6-1.6-1.5-1.8-2.1-1.5-1.1-2.01.21.01.11.1-0.6-2.22.0
Right kidney weight0.41.93.01.7-1.6-1.5-1.4-1.5-1.5-1.51.51.7-1.4-1.4-1.3-1.4-1.5-1.2-1.3-1.21.31.21.31.4-0.5-1.20.8
Cocaine induced anxiety0.10.10.2-0.40.40.40.30.40.50.5-0.3-0.40.20.30.30.30.2-0.10.4-0.1-0.3-0.2-0.4-0.3-0.30.2-0.2
Post-drug Anxiety0.70.71.90.9-0.7-0.8-0.8-1.0-0.7-0.70.70.9-0.8-0.8-0.7-0.9-1.1-1.1-0.3-1.40.50.70.60.6-1.0-1.00.8
Baseline Anxiety0.80.91.30.9-1.0-1.0-1.0-0.9-1.0-1.01.01.0-1.0-1.0-1.0-0.9-0.8-0.9-1.0-1.11.01.01.11.1-0.8-0.60.2
Tail length2.07.99.63.1-3.1-3.1-2.9-2.9-3.0-3.02.83.0-3.0-3.0-2.9-2.9-2.9-2.9-2.6-2.82.72.62.82.6-2.5-2.31.2
Length with tail1.66.810.63.1-2.6-2.9-2.5-3.0-3.1-3.12.32.9-2.7-2.6-2.4-2.9-3.3-2.5-1.8-2.81.82.02.01.8-1.7-3.12.6
Length without tail0.10.43.00.5-0.0-0.4-0.1-0.7-0.8-0.8-0.20.4-0.2-0.20.0-0.5-1.0-0.10.5-0.8-0.5-0.2-0.4-0.60.4-1.31.7
Times rat made contact with spout0.40.50.80.5-0.7-0.7-0.7-0.5-0.6-0.60.80.5-0.8-0.7-0.8-0.6-0.4-0.9-0.9-0.80.90.80.80.8-0.8-0.1-0.4
Lifetime Intake0.20.31.60.10.20.10.3-0.10.10.1-0.7-0.00.10.20.3-0.1-0.2-0.20.9-0.8-0.9-0.6-0.7-0.70.1-0.91.3
Liver weight, left0.00.00.20.10.10.10.20.0-0.0-0.0-0.00.00.10.10.20.0-0.10.20.3-0.0-0.2-0.2-0.1-0.10.4-0.30.5
Liver weight, right0.81.32.1-1.31.21.21.31.31.31.3-1.2-1.41.01.21.11.21.30.81.00.6-1.1-1.1-1.1-1.10.81.2-0.8
Locomotor activity0.00.00.00.0-0.0-0.1-0.1-0.1-0.1-0.1-0.00.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.00.00.1-0.1-0.10.1
Locomotor testing distance0.20.30.8-0.30.60.40.60.30.30.3-0.7-0.20.50.40.50.2-0.10.50.70.2-0.7-0.8-0.9-0.70.5-0.40.9
Locomotor testing rearing0.51.12.21.1-0.9-1.0-0.9-1.1-1.0-1.00.81.2-1.1-1.1-1.1-1.2-1.2-1.2-0.7-1.50.80.80.60.8-1.2-1.31.0
Locomotion in novel chamber0.30.41.0-0.60.60.70.50.70.90.9-0.3-0.80.60.60.50.70.80.50.30.6-0.3-0.3-0.2-0.30.11.0-1.0
Locomotion in novel chamber post-restriction1.22.03.61.1-1.9-1.3-1.6-1.0-0.7-0.71.71.0-1.4-1.3-1.5-1.0-0.6-1.6-1.8-0.81.61.91.91.9-1.90.2-1.2
Fecal boli incidents, locomotor time 10.81.11.8-1.41.11.10.91.11.21.2-0.8-1.21.21.11.01.21.01.30.81.3-0.8-0.7-0.7-0.81.31.2-0.9
Change in fecal boli incidents, locomotor task0.80.81.51.1-0.9-0.9-0.8-1.0-1.0-1.00.71.2-0.8-0.8-0.7-1.0-1.1-0.8-0.4-1.10.40.50.50.5-0.5-1.21.2
Time >=10cm from walls, locomotor time 10.20.21.40.50.1-0.20.1-0.4-0.6-0.6-0.00.4-0.0-0.1-0.0-0.3-0.50.10.3-0.5-0.2-0.4-0.3-0.30.5-0.91.2
Bouts of movement, locomotor time 11.92.12.8-1.71.61.51.51.61.61.6-1.5-1.61.51.51.51.51.51.41.41.5-1.3-1.3-1.3-1.41.11.3-0.8
Total resting periods, locomotor time 12.52.73.8-1.91.71.71.61.91.91.9-1.6-1.91.61.71.61.81.81.61.51.8-1.3-1.3-1.3-1.41.31.8-1.3
Rest time, locomotor task time 11.51.87.0-1.70.71.10.81.71.71.7-0.6-1.80.91.10.91.51.90.90.51.8-0.5-0.1-0.1-0.40.52.5-2.7
Distance moved, locomotor task time 11.72.55.91.9-1.1-1.6-1.2-2.0-2.0-2.01.01.9-1.4-1.5-1.3-1.8-2.1-1.3-0.8-2.00.80.70.70.7-1.0-2.42.4
Vertical activity count, locomotor time 10.71.67.11.4-0.7-1.0-0.8-1.7-1.4-1.40.51.5-0.8-1.0-0.8-1.4-2.0-0.8-0.2-1.70.20.10.20.1-0.6-2.42.7
Time >=10cm from walls, locomotor time 20.10.10.30.3-0.3-0.3-0.2-0.4-0.4-0.40.30.4-0.2-0.3-0.3-0.4-0.5-0.2-0.2-0.20.30.10.00.20.0-0.50.6
Bouts of movement, locomotor time 20.30.50.80.7-0.4-0.5-0.7-0.8-0.6-0.60.70.8-0.5-0.8-0.8-0.8-0.7-0.6-0.6-0.80.80.70.60.6-0.9-0.60.3
Total resting periods, locomotor time 20.10.10.40.3-0.1-0.1-0.3-0.4-0.1-0.10.30.4-0.2-0.4-0.4-0.4-0.4-0.3-0.3-0.40.40.40.30.3-0.6-0.30.1
Rest time, locomotor task time 20.91.11.8-1.10.91.10.91.11.41.4-1.0-1.21.01.11.01.21.21.00.91.4-1.1-0.6-0.7-0.90.81.3-1.0
Distance moved, locomotor task time 20.70.81.80.6-0.9-1.0-0.9-0.7-0.8-0.81.00.6-1.0-0.9-1.0-0.8-0.5-1.0-1.1-0.61.31.11.01.0-1.3-0.3-0.2
Vertical activity count, locomotor time 20.60.91.30.8-0.9-1.0-0.9-1.1-1.0-1.00.91.0-0.9-1.0-0.9-1.1-1.1-0.9-0.8-1.01.00.70.70.7-0.9-1.10.9
Light reinforcement 11.02.411.91.7-0.6-1.2-0.5-1.5-1.9-1.90.61.8-1.0-1.3-1.0-1.8-2.2-1.0-0.3-2.20.4-0.3-0.20.0-0.3-3.13.4
Light reinforcement 20.91.310.51.0-0.0-0.5-0.1-1.1-1.1-1.1-0.20.9-0.3-0.4-0.1-0.9-1.7-0.30.8-1.5-0.8-0.6-0.5-0.80.7-2.53.2
Bone: marrow area1.43.14.21.9-1.8-1.9-1.8-2.0-1.9-1.91.81.8-1.8-1.8-1.7-1.9-2.1-1.8-1.4-2.01.41.61.71.4-1.2-1.81.3
Bone: maximum diameter2.75.16.82.2-2.5-2.4-2.4-2.2-2.2-2.22.62.1-2.4-2.4-2.4-2.3-1.8-2.4-2.4-2.22.42.42.62.4-2.5-1.30.2
Bone: maximum force3.76.58.02.7-2.8-2.8-2.5-2.4-2.6-2.62.82.5-2.8-2.7-2.8-2.6-2.1-2.7-2.8-2.52.72.62.72.7-2.7-1.60.4
Bone: maximum moment3.05.36.72.4-2.6-2.5-2.3-2.1-2.3-2.32.62.2-2.5-2.4-2.5-2.3-1.7-2.4-2.6-2.22.52.42.52.5-2.5-1.20.0
Mean time between licks in bursts0.20.40.7-0.70.60.70.70.70.70.7-0.6-0.70.70.70.70.70.70.70.60.8-0.6-0.7-0.5-0.60.60.6-0.4
Mean num. licks in bursts1.93.03.6-1.81.81.81.71.61.81.8-1.8-1.81.81.81.81.81.61.91.81.9-1.8-1.7-1.6-1.71.81.4-0.7
Cd content in liver1.01.11.61.3-1.1-1.1-0.9-1.0-1.2-1.21.01.2-1.1-1.1-1.1-1.2-0.9-1.1-0.9-0.90.91.01.00.9-1.0-1.10.7
Co content in liver0.50.61.2-0.50.90.71.00.40.50.5-0.8-0.40.70.70.80.50.20.81.00.5-1.0-1.1-1.0-1.00.9-0.20.7
Cu content in liver1.72.02.7-1.61.41.51.51.71.51.5-1.4-1.61.51.51.41.51.61.51.21.7-1.1-1.1-1.2-1.21.11.4-0.9
Fe content in liver0.91.12.6-0.71.11.01.40.90.70.7-1.2-0.71.01.01.10.80.51.01.30.6-1.3-1.6-1.4-1.31.3-0.10.8
K content in liver0.30.30.6-0.30.60.50.50.30.30.3-0.6-0.30.60.50.60.3-0.10.60.80.4-0.7-0.7-0.7-0.80.7-0.20.7
Mg content in liver0.90.91.4-1.00.91.00.80.81.01.0-0.9-1.01.11.01.11.00.51.11.21.0-1.1-0.9-0.8-1.21.10.5-0.0
Mn content in liver1.21.32.31.0-1.3-1.2-1.3-0.9-1.0-1.01.41.0-1.2-1.2-1.3-1.0-0.7-1.2-1.4-0.91.41.51.51.4-1.3-0.3-0.4
Na content in liver1.31.42.0-1.31.21.21.41.31.21.2-1.1-1.31.21.21.21.21.31.21.11.3-1.0-1.4-1.0-1.11.11.0-0.6
Rb content in liver5.26.18.8-2.52.72.63.02.72.52.5-2.5-2.52.62.62.62.52.32.52.62.2-2.6-2.8-2.5-2.62.41.6-0.5
Se content in liver2.42.94.51.5-1.8-1.8-2.0-1.6-1.6-1.61.81.6-1.8-1.8-1.8-1.6-1.1-1.9-1.9-1.71.92.11.91.9-1.9-0.8-0.1
Sr content in liver0.40.31.40.7-0.6-0.6-1.0-1.2-0.6-0.60.50.7-0.4-0.5-0.5-0.6-0.6-0.2-0.40.10.40.80.40.4-0.2-0.60.4
Zn content in liver0.10.10.30.2-0.4-0.3-0.3-0.3-0.2-0.20.40.2-0.2-0.3-0.3-0.2-0.2-0.1-0.40.20.40.50.50.4-0.40.1-0.3
Bone: minimum diameter0.00.10.4-0.1-0.10.10.00.20.20.20.1-0.30.10.10.00.20.40.0-0.00.30.00.20.30.0-0.10.5-0.6
Time in familiar zone, hab. session 10.90.86.1-1.00.30.50.21.01.01.0-0.2-0.90.40.50.30.91.50.3-0.31.00.30.30.20.3-0.22.0-2.5
Time in novel zone, hab. session 11.91.93.8-0.81.51.21.50.80.80.8-1.5-0.91.41.21.40.90.11.51.90.8-1.9-1.9-1.8-1.91.9-0.71.8
Total zone transitions, hab. session 10.00.00.10.1-0.1-0.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.1-0.10.1-0.20.20.10.10.20.1-0.3-0.0-0.1
Total locomotion distance, hab. session 10.50.71.60.5-0.9-0.7-1.0-0.5-0.4-0.40.90.5-0.8-0.7-0.8-0.5-0.1-0.7-1.1-0.11.11.31.11.1-1.20.5-1.1
Locomotion velocity, hab. session 11.72.44.11.4-1.8-1.6-1.9-1.4-1.3-1.31.71.3-1.6-1.6-1.7-1.4-1.0-1.5-1.8-1.01.92.01.91.9-2.0-0.3-0.6
Time in familiar zone, hab. session 20.80.93.4-1.10.70.80.61.11.11.1-0.5-1.10.80.80.61.01.40.80.21.3-0.2-0.2-0.4-0.30.21.7-1.8
Time in novel zone, hab. session 21.51.52.9-0.81.31.11.40.90.80.8-1.4-0.81.21.21.30.90.31.21.70.6-1.6-1.7-1.6-1.61.7-0.41.3
Total zone transitions, hab. session 20.70.81.91.0-0.7-0.9-0.8-1.1-1.1-1.10.81.0-0.8-0.9-0.8-1.1-1.4-0.7-0.6-1.00.60.50.60.5-0.6-1.41.3
Total locomotion distance, hab. session 20.91.21.51.1-1.1-1.1-1.2-1.1-1.1-1.11.21.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.01.11.21.11.1-1.2-0.80.4
Locomotion velocity, hab. session 21.21.62.01.2-1.3-1.3-1.4-1.3-1.2-1.21.41.2-1.3-1.3-1.3-1.3-1.3-1.2-1.3-1.21.31.41.31.3-1.4-0.90.3
Novel to familiar place preference ratio3.63.96.0-1.82.22.02.21.71.71.7-2.2-1.82.12.02.21.81.22.22.51.8-2.4-2.5-2.3-2.42.30.50.6
Novelty place preference4.95.27.5-2.12.52.42.62.12.12.1-2.5-2.22.42.42.52.11.62.52.72.1-2.6-2.7-2.6-2.72.60.90.3
Time in novel zone, NPP test5.96.49.1-2.42.82.62.82.32.32.3-2.8-2.42.72.62.72.41.82.73.02.3-2.9-3.0-2.8-3.02.81.00.3
Total zone transitions, NPP test0.81.12.71.2-0.9-1.1-0.9-1.3-1.3-1.30.91.3-0.9-1.0-0.9-1.2-1.5-0.8-0.7-1.10.70.60.50.6-0.7-1.61.6
Total locomotion distance, NPP test2.02.74.41.8-1.5-1.7-1.7-1.9-1.9-1.91.51.8-1.6-1.7-1.6-1.8-2.1-1.4-1.3-1.61.31.41.21.2-1.4-2.01.6
Locomotion velocity, NPP test2.53.65.22.1-1.9-2.0-2.0-2.2-2.1-2.11.82.0-1.9-2.0-1.9-2.1-2.3-1.7-1.7-1.81.71.71.61.6-1.7-2.01.5
Intraocular pressure2.43.54.82.2-2.0-2.0-1.9-2.2-2.0-2.01.72.1-1.9-2.0-1.9-2.1-2.1-1.9-1.6-2.11.51.41.61.5-1.5-2.01.5
Delta distance traveled before/after self-admin0.10.10.6-0.40.20.20.20.40.40.40.0-0.50.10.20.10.30.5-0.1-0.1-0.10.10.00.00.1-0.20.6-0.7
Delta ambulatory time before/after self-admin0.50.61.3-1.00.70.80.71.01.11.1-0.6-1.10.70.80.70.91.10.40.50.3-0.5-0.5-0.4-0.30.21.1-1.1
Parametrial fat weight0.10.20.90.10.30.20.60.3-0.1-0.1-0.30.10.40.20.30.0-0.00.60.30.5-0.4-0.8-0.8-0.40.7-0.61.0
Pavlov. Cond. lever latency7.29.110.9-3.13.13.23.23.23.23.2-3.0-3.13.23.23.13.23.13.22.83.3-2.7-2.9-2.8-2.72.92.7-1.6
Pavlov. Cond. magazine entry latency0.60.81.00.9-1.0-0.9-1.0-0.9-0.9-0.91.00.8-0.9-0.9-1.0-0.9-0.9-0.8-0.9-0.70.90.90.90.9-1.0-0.60.2
Pavlov. Cond. change in total contacts3.03.24.01.8-1.8-1.9-1.9-1.9-2.0-2.01.81.8-1.9-1.9-1.8-1.9-2.0-1.8-1.6-2.01.61.71.61.5-1.7-1.71.1
Pavlov. Cond. index score3.64.55.52.1-2.2-2.3-2.3-2.2-2.2-2.22.32.1-2.2-2.2-2.2-2.2-2.1-2.2-2.1-2.22.02.22.12.0-2.2-1.60.7
Pavlov. Cond. latency score3.24.15.02.0-2.1-2.2-2.2-2.1-2.1-2.12.22.0-2.1-2.1-2.1-2.1-2.0-2.1-1.9-2.11.92.12.01.9-2.1-1.60.8
Pavlov. Cond. lever contacts6.78.09.42.9-2.9-3.0-3.1-3.0-3.0-3.02.92.9-3.0-3.0-2.9-3.0-2.9-3.0-2.7-3.12.62.82.72.6-2.8-2.41.3
Pavlov. Cond. magazine entry number0.81.01.4-1.01.11.11.11.01.01.0-1.2-1.01.11.11.11.00.81.01.20.8-1.1-1.1-1.0-1.11.20.50.0
Pavlov. Cond. intertrial magazine entries0.20.30.60.4-0.6-0.6-0.7-0.6-0.5-0.50.50.4-0.6-0.5-0.5-0.5-0.5-0.6-0.5-0.50.50.70.70.5-0.5-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.3.64.45.52.0-2.2-2.2-2.3-2.1-2.1-2.12.32.0-2.2-2.2-2.2-2.1-2.0-2.2-2.2-2.12.12.32.12.1-2.2-1.40.5
Pavlov. Cond. response bias4.45.46.32.4-2.4-2.5-2.5-2.4-2.5-2.52.42.4-2.5-2.5-2.5-2.5-2.3-2.4-2.3-2.32.32.32.22.2-2.4-1.90.9
Pavlov. Cond. lever latency2.73.65.3-1.92.22.02.21.91.71.7-2.0-1.82.12.02.11.71.32.02.21.5-2.2-2.3-2.2-2.22.20.50.6
Pavlov. Cond. magazine entry latency0.20.20.7-0.60.40.50.50.60.50.5-0.4-0.60.40.50.40.60.80.40.20.5-0.3-0.3-0.4-0.20.10.8-0.8
Pavlov. Cond. change in total contacts0.91.53.00.8-1.4-1.1-1.3-0.8-0.7-0.71.30.8-1.2-1.1-1.3-0.8-0.1-1.1-1.7-0.41.71.61.61.7-1.70.6-1.6
Pavlov. Cond. index score0.40.51.50.4-0.8-0.6-0.7-0.4-0.3-0.30.70.4-0.7-0.6-0.7-0.30.1-0.7-1.0-0.21.01.00.91.0-1.00.6-1.2
Pavlov. Cond. latency score0.50.71.70.5-0.9-0.7-0.9-0.5-0.4-0.40.90.5-0.8-0.7-0.9-0.40.0-0.8-1.2-0.31.11.11.01.2-1.10.6-1.3
Pavlov. Cond. lever contacts2.02.84.21.6-1.9-1.7-1.9-1.6-1.4-1.41.71.5-1.8-1.7-1.8-1.5-1.1-1.8-1.9-1.22.02.11.92.0-2.0-0.4-0.6
Pavlov. Cond. magazine entry number0.30.42.2-0.10.50.40.40.00.10.1-0.5-0.10.50.40.50.1-0.50.50.90.1-0.8-0.7-0.6-0.90.9-0.91.5
Pavlov. Cond. intertrial magazine entries0.20.30.60.7-0.6-0.6-0.6-0.7-0.6-0.60.60.6-0.5-0.6-0.6-0.6-0.8-0.5-0.4-0.40.40.40.60.5-0.4-0.70.5
Pavlov. Cond. lever-magazine prob. diff.0.40.61.80.4-0.8-0.6-0.7-0.3-0.3-0.30.80.4-0.7-0.6-0.8-0.30.2-0.7-1.1-0.21.01.00.91.1-1.00.7-1.3
Pavlov. Cond. response bias1.01.42.51.0-1.3-1.1-1.3-0.9-0.9-0.91.20.9-1.3-1.1-1.3-0.9-0.4-1.2-1.5-0.71.51.51.41.5-1.60.2-1.0
Time in closed arm before self-admin0.40.61.0-0.50.91.00.70.71.01.0-0.7-0.71.00.80.80.80.70.90.80.8-0.7-0.6-0.8-0.40.60.6-0.3
Time in closed arm after self-admin0.30.31.7-0.50.10.20.20.80.40.40.0-0.70.10.30.20.50.90.1-0.10.60.20.1-0.00.3-0.21.1-1.3
Time in open arm before self-admin1.31.42.41.2-1.3-1.4-1.1-1.4-1.5-1.51.01.4-1.2-1.1-1.0-1.3-1.5-1.0-0.7-1.20.60.70.90.5-0.6-1.51.3
Time in open arm after self-admin0.80.92.31.1-0.7-0.8-0.8-1.4-1.0-1.00.51.2-0.7-0.8-0.7-1.0-1.5-0.7-0.3-1.30.20.40.50.4-0.3-1.51.5
Bone: periosteal estimation2.14.45.42.2-2.3-2.3-2.1-2.1-2.2-2.22.32.1-2.2-2.2-2.2-2.2-1.9-2.2-2.1-2.22.12.12.32.1-2.0-1.50.6
Bone: periosteal perimeter0.71.21.61.3-1.1-1.2-0.9-1.1-1.3-1.31.11.2-1.1-1.1-1.1-1.2-1.2-1.0-0.8-1.20.90.81.00.9-0.9-1.20.9
Bone: post-yield work2.53.65.42.1-1.9-2.0-1.9-2.2-2.1-2.11.82.1-1.9-2.0-1.9-2.1-2.3-1.8-1.6-1.91.61.61.61.5-1.6-2.11.6
Progressive ratio test 1 active lever presses0.91.12.8-0.61.00.81.10.60.60.6-1.6-0.70.70.91.10.60.40.41.6-0.3-1.7-1.4-1.7-1.70.9-0.61.4
Progressive ratio test 1 breakpoint0.70.92.4-0.50.90.61.00.50.40.4-1.4-0.60.60.80.90.50.30.31.5-0.4-1.5-1.3-1.5-1.50.7-0.61.3
Progressive ratio test 1 inactive lever presses0.71.04.81.2-0.6-0.8-0.5-1.2-1.1-1.10.21.2-0.7-0.8-0.6-1.1-1.4-0.8-0.1-1.50.0-0.0-0.1-0.1-0.1-2.02.2
Progressive ratio test 2 active lever presses1.31.54.3-0.71.21.11.30.70.90.9-1.7-0.81.01.11.30.80.40.62.0-0.2-2.1-1.7-1.8-1.71.1-0.51.4
Progressive ratio test 2 breakpoint1.41.64.4-0.81.21.11.30.71.01.0-1.7-0.91.11.21.40.80.40.72.0-0.2-2.1-1.7-1.8-1.81.2-0.51.5
Progressive ratio test 2 inactive lever presses0.10.10.70.3-0.3-0.2-0.1-0.3-0.1-0.1-0.10.3-0.2-0.1-0.1-0.2-0.4-0.50.3-0.8-0.5-0.1-0.1-0.1-0.3-0.60.7
Incentive Sensitization - Responses0.40.51.3-0.50.80.70.90.40.60.6-0.9-0.60.60.60.70.40.30.01.1-0.7-1.2-1.1-1.0-1.00.3-0.30.8
Incentive Sensitization - Breakpoint0.50.61.5-0.60.90.70.90.50.70.7-0.9-0.70.60.70.80.50.30.11.2-0.6-1.2-1.1-1.0-1.00.4-0.30.8
Sum of active levers in priming session hrs 5-63.73.45.7-1.72.21.82.11.61.31.3-2.2-1.51.91.92.01.61.12.12.21.3-2.3-2.3-2.3-2.32.40.40.8
Progressive ratio0.00.00.10.10.10.10.20.1-0.0-0.0-0.10.20.10.10.10.0-0.10.20.3-0.0-0.2-0.2-0.0-0.10.4-0.20.3
Food seeking constrained by brief footshock6.98.513.03.6-2.5-2.9-2.8-3.4-3.2-3.22.53.5-2.8-3.0-2.8-3.3-3.6-2.9-2.3-3.42.12.22.12.2-2.2-3.52.8
Seeking ratio, punishment vs. effort1.82.63.51.8-1.6-1.7-1.7-1.9-1.7-1.71.51.7-1.7-1.7-1.6-1.7-1.8-1.8-1.5-1.91.31.51.31.4-1.6-1.61.0
Retroperitoneal fat weight0.41.52.8-1.41.11.31.31.61.41.4-1.0-1.51.21.21.11.31.61.30.71.7-0.7-1.0-1.0-0.80.71.5-1.3
Reaction time number correct0.10.10.70.6-0.3-0.2-0.2-0.5-0.2-0.20.10.6-0.1-0.2-0.2-0.4-0.7-0.10.0-0.50.0-0.10.10.2-0.1-0.70.9
Reaction time mean minus median0.41.15.10.1-1.0-0.8-0.9-0.3-0.5-0.51.00.3-0.9-0.7-0.9-0.20.5-0.7-1.50.11.41.31.41.6-1.11.3-2.3
Reaction time mean minus median AUC0.61.53.30.8-1.4-1.2-1.3-0.9-0.9-0.91.30.9-1.3-1.1-1.3-0.7-0.2-1.2-1.6-0.51.61.61.71.8-1.40.6-1.6
Reaction time num false alarms0.10.10.50.1-0.3-0.1-0.4-0.20.20.20.2-0.1-0.2-0.1-0.2-0.00.1-0.3-0.3-0.10.30.50.60.2-0.20.5-0.7
Reaction time num false alarms AUC0.30.50.80.7-0.8-0.7-0.8-0.9-0.6-0.60.60.6-0.7-0.7-0.7-0.7-0.6-0.8-0.7-0.80.70.80.90.6-0.5-0.40.0
Reaction time trials correct on left0.10.10.70.6-0.3-0.2-0.2-0.5-0.2-0.20.10.6-0.1-0.2-0.2-0.4-0.7-0.10.0-0.50.0-0.10.10.2-0.1-0.70.9
Reaction time trials on left0.10.10.60.5-0.2-0.1-0.1-0.4-0.1-0.10.00.50.0-0.2-0.1-0.3-0.5-0.00.1-0.4-0.0-0.20.00.10.0-0.60.8
Reaction time mean1.11.76.5-1.70.91.01.11.61.31.3-0.7-1.60.91.10.91.52.11.00.31.6-0.3-0.5-0.5-0.30.62.4-2.6
Reaction time mean AUC1.32.07.4-1.81.01.21.11.81.41.4-0.9-1.71.01.31.01.62.21.10.41.7-0.4-0.5-0.6-0.40.72.6-2.7
Median of all reaction times2.43.45.8-2.21.71.81.92.21.91.9-1.5-2.21.71.81.72.12.41.71.22.0-1.2-1.4-1.4-1.31.42.4-2.1
Reaction time omissions1.72.43.5-1.81.71.51.61.71.31.3-1.5-1.81.61.61.61.71.61.91.41.9-1.3-1.5-1.5-1.51.61.4-0.8
Reaction time false alarm rate0.00.10.6-0.3-0.10.0-0.10.00.20.2-0.0-0.4-0.10.0-0.00.20.3-0.1-0.10.10.10.30.3-0.10.00.6-0.8
Reaction time premature initiation rate2.43.35.4-2.31.91.81.92.21.81.8-1.6-2.21.71.81.61.92.31.91.12.1-1.2-1.5-1.6-1.51.42.1-1.7
Reaction time premature initiations1.22.23.1-1.81.61.51.61.71.51.5-1.4-1.71.51.51.41.51.71.71.01.7-1.0-1.4-1.4-1.31.21.5-1.1
Std. dev. reaction times0.40.76.2-0.7-0.2-0.0-0.10.50.30.30.2-0.6-0.10.1-0.10.51.20.1-0.70.90.70.60.60.7-0.51.8-2.5
Reaction time trials completed0.10.10.60.5-0.2-0.1-0.1-0.4-0.1-0.10.00.50.0-0.2-0.1-0.3-0.5-0.00.1-0.4-0.0-0.20.00.10.0-0.60.8
Reaction time trials AUC0.00.10.60.5-0.2-0.1-0.1-0.4-0.1-0.10.10.50.0-0.2-0.1-0.3-0.50.00.1-0.3-0.0-0.20.00.10.0-0.60.8
Run reversals in cocaine runway, females0.20.20.60.3-0.40.2-0.4-0.10.50.50.30.30.1-0.0-0.10.10.20.0-0.40.70.30.50.40.8-0.00.5-0.7
Run reversals in cocaine runway, males0.10.10.2-0.40.30.30.30.30.30.3-0.3-0.30.30.30.30.30.30.20.20.1-0.2-0.2-0.2-0.30.30.3-0.2
Latency to leave start box in cocaine runway0.70.81.20.7-0.8-0.9-0.8-0.7-1.0-1.01.00.9-0.9-1.0-1.0-0.9-0.6-0.8-1.1-0.51.10.90.91.1-1.0-0.50.1
Latency to leave start box in cocaine runway, F0.10.10.3-0.20.40.30.40.30.10.1-0.2-0.10.40.20.30.10.10.50.30.4-0.3-0.5-0.5-0.30.5-0.30.5
Latency to leave start box in cocaine runway, M2.62.43.01.5-1.4-1.7-1.6-1.6-1.7-1.71.61.6-1.7-1.7-1.7-1.6-1.5-1.6-1.6-1.61.61.51.51.5-1.6-1.20.5
Std. dev. time between licks in bursts0.30.40.6-0.70.60.70.60.60.80.8-0.7-0.70.70.70.70.70.70.60.70.6-0.7-0.6-0.5-0.60.60.7-0.5
Total sessions with >9 infusions0.40.42.80.20.40.00.4-0.2-0.3-0.3-0.80.10.00.10.3-0.2-0.3-0.20.9-0.9-1.0-0.8-0.9-0.90.1-1.21.7
Short access day 1 total inactive lever presses0.71.03.81.1-0.4-0.9-0.4-1.0-1.3-1.30.41.0-0.8-0.8-0.7-1.1-1.3-0.8-0.2-1.40.30.0-0.00.1-0.6-1.81.9
Short access day 10 total inactive lever presses0.51.12.20.8-0.9-1.1-0.9-0.8-1.1-1.11.20.9-1.1-1.2-1.2-1.1-0.8-1.1-1.3-1.01.51.01.01.1-1.4-0.60.1
Short access day 1 total infusions0.40.63.90.40.2-0.20.3-0.3-0.6-0.6-0.70.3-0.2-0.00.1-0.4-0.6-0.40.8-1.1-0.9-0.8-0.9-0.80.0-1.52.0
Short access day 10 total infusions0.40.52.90.10.50.30.6-0.0-0.1-0.1-0.90.00.40.40.50.0-0.30.31.1-0.4-1.2-1.0-1.2-1.00.6-1.11.7
Short access total infusions0.70.93.5-0.20.80.50.90.20.20.2-1.3-0.30.50.60.80.2-0.10.21.4-0.6-1.5-1.3-1.5-1.40.6-1.11.9
Short access day 1 locomotion1.62.03.9-1.01.71.31.71.10.80.8-1.9-1.01.41.31.41.10.91.61.81.0-1.9-1.9-2.0-1.81.5-0.11.0
Short access day 10 total locomotion0.81.42.2-1.21.31.31.21.21.41.4-1.2-1.31.31.21.11.21.41.31.01.5-1.1-0.9-1.0-0.90.71.2-0.9
Short access total locomotion0.60.71.7-0.31.10.80.90.40.40.4-1.2-0.40.90.80.90.60.41.11.20.7-1.3-1.1-1.2-1.10.9-0.20.8
One hour access (0.3 mA shock)0.20.31.40.7-0.4-0.1-0.3-0.6-0.1-0.1-0.20.6-0.1-0.00.1-0.2-0.7-0.40.7-0.7-0.8-0.1-0.1-0.30.4-0.91.2
Compulsive drug intake0.30.30.90.4-0.8-0.3-0.7-0.4-0.0-0.00.90.5-0.3-0.5-0.5-0.3-0.2-0.3-0.80.30.70.80.90.7-0.60.3-0.7
One hour access (shock baseline)0.30.53.40.30.20.10.3-0.3-0.2-0.2-0.70.20.10.20.4-0.1-0.6-0.11.1-0.7-1.2-0.8-0.9-0.80.7-1.21.8
Social response proportion1.92.23.8-1.81.51.51.41.71.61.6-1.1-1.71.61.51.41.61.71.71.01.9-0.9-1.1-1.0-1.11.11.8-1.4
Social responses0.81.01.51.0-1.0-0.9-1.1-1.1-0.9-0.91.21.0-0.9-1.1-1.1-1.0-1.0-0.9-1.2-0.91.21.01.11.1-1.0-0.70.3
Social time0.00.00.0-0.20.20.10.20.20.00.00.0-0.20.10.10.10.10.00.10.2-0.2-0.1-0.1-0.2-0.20.1-0.00.1
Soleus weight0.30.86.60.60.2-0.20.3-0.5-0.8-0.8-0.40.50.1-0.10.2-0.5-1.10.20.8-0.7-0.8-0.9-0.7-0.90.8-1.92.6
Bone: stiffness4.98.09.62.9-3.1-3.1-2.9-2.7-2.9-2.93.02.8-3.1-3.0-3.0-2.9-2.3-3.0-3.0-2.82.92.93.02.9-3.0-1.80.5
Tibialis anterior weight8.428.635.35.9-5.5-5.8-5.3-5.5-5.9-5.95.35.9-5.6-5.6-5.5-5.7-5.6-5.5-5.0-5.84.94.64.84.9-4.8-5.03.1
Time to tail flick, vehicle, before self-admin0.70.83.5-0.70.50.90.60.81.11.1-0.7-0.70.90.90.81.00.81.00.81.9-0.7-0.4-0.5-0.10.81.0-0.9
Time to tail flick, vehicle, after self-admin0.00.00.1-0.1-0.3-0.2-0.10.0-0.0-0.00.1-0.1-0.2-0.1-0.2-0.10.2-0.2-0.30.20.30.20.20.0-0.20.2-0.3
Time to tail flick, test, before self-admin0.40.40.70.8-0.7-0.5-0.8-0.8-0.3-0.30.70.8-0.6-0.6-0.6-0.6-0.7-0.8-0.4-0.80.30.80.90.6-0.8-0.40.1
Time to tail flick, test, after self-admin2.22.35.01.5-1.8-1.3-1.8-1.2-0.9-0.91.91.5-1.4-1.5-1.6-1.2-0.8-1.3-1.8-0.51.82.02.22.2-1.8-0.1-0.9
Delta time to tail flick, vehicle, before/after SA0.30.31.00.2-0.5-0.6-0.4-0.4-0.6-0.60.50.2-0.6-0.6-0.6-0.6-0.4-0.8-0.7-1.00.60.40.40.1-0.7-0.40.2
Delta time to tail flick, test, before/after SA0.10.10.9-0.2-0.10.1-0.10.30.20.20.2-0.20.1-0.0-0.10.10.50.2-0.50.70.60.30.30.5-0.20.7-0.9
Tibia length0.10.32.80.7-0.1-0.20.3-0.2-0.5-0.50.00.6-0.1-0.2-0.1-0.5-0.8-0.00.2-0.4-0.2-0.6-0.3-0.30.3-1.31.7
Ambulatory time before self-admin2.74.07.52.1-1.7-2.4-1.7-2.1-2.7-2.71.72.1-2.2-2.0-1.9-2.2-2.2-2.0-1.5-2.41.51.31.31.1-1.7-2.31.9
Ambulatory time after self-admin0.70.82.10.8-0.7-1.1-0.7-0.8-1.2-1.20.90.7-1.1-0.9-0.9-0.9-0.8-1.2-0.8-1.40.80.70.70.6-1.2-0.80.5
Bone: tissue strength0.20.20.30.4-0.5-0.5-0.4-0.4-0.4-0.40.60.4-0.5-0.5-0.5-0.4-0.4-0.4-0.5-0.30.60.50.50.5-0.6-0.2-0.0
Total heroin consumption1.51.83.8-1.01.61.11.61.00.60.6-1.8-0.91.21.31.41.00.71.41.70.5-1.7-1.9-1.9-1.91.7-0.31.3
Bone: trabecular number1.11.83.41.2-1.5-1.4-1.6-1.3-1.1-1.11.41.2-1.4-1.3-1.4-1.1-0.8-1.3-1.6-0.81.51.81.71.6-1.6-0.3-0.5
Bone: trabecular spacing0.00.00.2-0.20.0-0.00.00.20.00.00.2-0.1-0.1-0.1-0.10.00.2-0.1-0.2-0.00.30.10.10.2-0.30.3-0.5
Bone: trabecular thickness0.20.20.6-0.50.30.40.10.40.60.6-0.4-0.60.40.50.40.50.60.40.30.7-0.3-0.0-0.1-0.30.20.7-0.7
Bone: trabecular tissue density3.45.05.92.4-2.3-2.4-2.3-2.2-2.4-2.42.22.4-2.4-2.4-2.4-2.4-2.2-2.4-2.3-2.32.22.02.02.2-2.3-1.91.0
Water consumed over 24 hours0.81.11.91.0-1.0-1.1-1.0-0.9-1.0-1.01.21.0-1.1-1.1-1.1-1.1-0.8-1.3-1.1-1.41.11.01.11.1-1.2-0.60.1
Number of responses in last shaping day1.01.17.20.10.90.30.8-0.1-0.5-0.5-1.10.00.50.30.5-0.2-0.70.81.1-0.2-1.2-1.4-1.5-1.51.0-1.82.7