Hub : Genes

Atosb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_039109529.1 0.02 0.02 9.4e-03 0.01 0.01 0 0.01 1.9e-02 2.3e-02 1.2e-01 2.3e-02
2 PL intron excision ratio chr5_57265299_57268368 0.03 0.02 1.3e-03 0.02 0.02 0.02 0.02 1.2e-03 1.0e-03 2.3e-03 2.1e-03
3 BLA isoform ratio XM_039109529.1 0.05 0.04 9.3e-03 0.03 0.03 0.02 0.03 1.7e-02 1.1e-02 2.0e-02 1.4e-02
4 PL isoform ratio XM_039109529.1 0.04 0.03 2.4e-04 0.04 0.04 0.04 0.04 5.1e-05 8.4e-05 1.1e-05 6.9e-05
5 Adipose mRNA stability Atosb 0.11 0.08 5.7e-11 0.1 0.1 0.1 0.1 3.3e-11 9.4e-11 3.2e-11 3.8e-11
6 Brain alternative TSS XM_039109529.1 0.06 0.04 3.6e-05 0.04 0.05 0.05 0.01 1.4e-04 1.8e-05 2.7e-05 6.4e-02
7 Brain alternative TSS XM_039109529.1 0.06 0.04 5.2e-05 0.04 0.05 0.05 0 2.4e-04 2.5e-05 4.3e-05 1.4e-01
8 Liver isoform ratio XM_039109528.1 0.04 0.03 2.4e-05 0.04 0.04 0.04 0.04 8.7e-05 1.1e-05 1.6e-05 2.3e-05
9 Liver alternative TSS XM_039109528.1 0.03 0.02 5.5e-04 0.02 0.03 0.03 0.03 1.1e-03 2.2e-04 3.7e-04 4.5e-04
10 Brain intron excision ratio chr5_57265299_57268368 0.06 0.04 6.2e-05 0.04 0.04 0.04 0.04 7.2e-05 6.9e-05 1.1e-04 7.2e-05
11 Brain isoform ratio XM_039109529.1 0.05 0.04 3.3e-04 0.03 0.05 0.04 0.02 5.8e-04 1.7e-05 2.0e-04 2.3e-03
12 Liver alternative TSS XM_039109528.1 0.03 0.02 3.4e-04 0.03 0.03 0.03 0.03 5.8e-04 1.1e-04 1.8e-04 2.1e-04
13 Liver gene expression Atosb 0.2 0.1 0.0e+00 0.17 0.18 0.18 0.18 7.7e-19 6.8e-20 1.5e-19 3.4e-19
14 BLA alternative TSS XM_039109529.1 0.1 0.07 9.7e-04 0.04 0.04 0.04 0.04 2.3e-03 2.2e-03 4.9e-03 3.8e-03
15 pVTA isoform ratio XM_039109529.1 0.09 0.07 1.3e-03 0.06 0.03 0.05 0.06 1.8e-03 1.3e-02 3.4e-03 1.7e-03
16 BLA alternative TSS XM_039109529.1 0.1 0.07 7.0e-04 0.04 0.05 0.04 0.04 2.9e-03 1.3e-03 4.0e-03 2.5e-03
17 NAcc gene expression Atosb 0.05 0.03 1.6e-05 0.05 0.05 0.04 0.05 1.8e-06 4.9e-06 1.8e-05 4.2e-06
18 Adipose gene expression Atosb 0.23 0.14 0.0e+00 0.19 0.19 0.19 0.2 1.9e-20 2.1e-20 5.9e-21 3.3e-21
19 Brain gene expression Atosb 0.05 0.04 4.6e-04 0.04 0.03 0.03 -0 8.3e-05 1.7e-03 4.9e-04 1.0e+00
20 BLA isoform ratio XM_039109530.1 0.08 0.06 6.5e-03 0.03 0.02 0.02 0.02 6.9e-03 2.1e-02 4.5e-02 3.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.11.92.51.4-1.4-1.41.11.5-1.5-1.51.51.5-1.5-1.51.51.4-0.6-1.4-0.6-1.51.6-1.40.4
Area under the delay curve0.60.61.5-0.40.60.6-0.8-0.80.70.8-0.8-0.80.80.8-0.8-0.9-0.11.2-0.11.0-1.01.2-0.8
BMI with tail2.27.112.92.5-2.6-2.72.13.6-2.9-2.92.92.9-2.9-2.93.03.0-1.2-2.4-1.2-3.23.1-2.70.9
BMI without tail6.112.516.34.0-3.9-3.93.34.0-3.8-3.83.83.8-3.8-3.83.83.8-2.9-3.1-2.9-3.73.4-2.9-0.7
Body weight3.414.220.54.0-4.1-4.13.54.5-4.1-4.14.14.1-4.1-4.14.14.0-2.9-3.5-2.9-4.03.7-3.2-0.4
Weight adjusted by age0.20.31.40.6-0.5-0.50.4-0.1-0.2-0.20.20.2-0.2-0.10.10.2-1.10.3-1.10.2-0.10.6-1.2
Bone surface0.71.21.61.2-1.3-1.31.11.1-1.2-1.21.21.2-1.2-1.21.21.1-1.1-0.9-1.1-1.01.0-0.9-0.5
Bone volume0.71.11.41.2-1.1-1.21.01.2-1.2-1.21.21.2-1.2-1.21.21.1-0.8-1.0-0.8-1.11.1-1.0-0.1
Breakpoint value in progressive ratio session0.80.93.2-0.10.20.3-0.6-1.00.60.7-0.7-0.70.70.8-0.8-0.9-1.01.4-1.01.2-1.21.6-1.8
Number of licking bursts5.36.38.32.5-2.5-2.52.62.8-2.7-2.72.72.7-2.7-2.72.72.8-1.4-2.9-1.4-2.72.6-2.70.5
Context. condit. distance diff. score0.10.10.3-0.40.40.4-0.4-0.40.40.4-0.4-0.40.30.3-0.3-0.30.50.30.50.2-0.30.20.4
Locomotion velocity, session 11.61.711.71.1-1.2-1.11.2-0.6-0.6-0.50.50.4-0.4-0.30.20.1-2.80.3-2.80.3-0.30.5-3.4
Locomotion distance, session 10.60.73.70.9-0.9-0.90.8-0.1-0.6-0.50.50.5-0.5-0.40.40.3-1.70.1-1.7-0.10.00.0-1.9
Locomotion velocity, session 22.22.64.61.5-1.6-1.61.31.8-1.7-1.71.81.8-1.8-1.81.81.8-0.7-1.6-0.7-1.82.1-1.80.6
Locomotion distance, session 22.23.14.72.1-2.1-2.02.01.3-1.9-1.81.81.8-1.8-1.81.71.7-2.2-1.3-2.2-1.41.3-1.4-1.4
Locomotion velocity, session 30.30.42.70.5-0.4-0.40.5-0.4-0.1-0.10.10.1-0.1-0.0-0.0-0.1-1.20.1-1.30.3-0.40.4-1.6
Locomotion distance, session 32.22.43.51.8-1.8-1.81.61.3-1.6-1.61.61.6-1.6-1.61.51.4-1.9-1.1-1.9-1.31.1-1.1-1.2
Stereotopy head waving bouts, day 30.30.42.5-0.10.00.10.4-0.90.30.4-0.4-0.40.40.5-0.5-0.6-0.90.1-0.90.7-0.60.8-1.6
Stereotopy head waving duration, day 30.40.51.1-0.60.50.5-0.0-1.00.70.7-0.7-0.70.70.8-0.8-0.9-0.20.2-0.20.8-0.80.9-0.9
Locomotion velocity, session 70.00.10.1-0.10.20.2-0.3-0.20.20.2-0.2-0.20.20.2-0.2-0.30.20.20.20.2-0.30.30.1
Locomotion distance, session 70.20.30.50.7-0.6-0.60.50.3-0.6-0.60.50.5-0.5-0.50.50.5-0.7-0.2-0.7-0.30.5-0.4-0.5
Stereotopy head waving bouts, day 72.22.43.71.7-1.7-1.71.91.3-1.6-1.61.61.6-1.6-1.61.61.4-1.5-1.9-1.5-1.51.3-1.4-0.7
Stereotopy head waving duration, day 70.60.71.50.9-0.9-0.91.20.6-0.8-0.80.80.8-0.8-0.80.80.7-1.0-1.2-1.0-0.70.5-0.7-0.7
Locomotion velocity, session 80.20.21.60.4-0.4-0.40.6-0.4-0.1-0.10.10.1-0.1-0.10.00.1-1.00.1-1.00.2-0.20.1-1.3
Locomotion distance, session 80.30.41.50.8-0.7-0.70.7-0.0-0.5-0.50.50.5-0.5-0.40.40.4-1.2-0.1-1.2-0.20.2-0.2-1.2
Degree of sensitization distance1.01.01.3-1.11.11.1-1.0-1.11.11.1-1.1-1.11.11.0-1.0-1.01.00.81.01.0-0.70.80.5
Degree of sensitization stereotypy1.21.32.01.2-1.2-1.21.31.1-1.2-1.21.21.2-1.2-1.21.21.1-0.9-1.4-0.9-1.21.0-1.1-0.3
Conditioned locomotion0.20.31.80.1-0.1-0.00.4-0.90.20.2-0.2-0.30.30.3-0.3-0.4-0.80.2-0.80.6-0.70.3-1.3
Cocaine response after cond. corrected2.02.24.0-1.01.01.1-0.9-2.01.41.5-1.4-1.51.51.6-1.6-1.6-0.41.8-0.41.9-2.01.8-1.8
Cocaine response after cond. not corrected1.61.84.3-0.80.80.8-0.7-1.81.21.2-1.2-1.31.31.3-1.4-1.4-0.71.6-0.81.8-1.81.7-2.1
Cocaine response before conditioning0.91.11.41.1-1.1-1.11.11.2-1.2-1.21.11.1-1.2-1.21.21.1-0.6-1.2-0.6-1.21.1-1.10.2
Saline control response1.21.53.51.4-1.4-1.41.70.7-1.1-1.11.11.1-1.0-1.01.00.9-1.9-1.2-1.9-0.80.4-0.7-1.6
Bone: connectivity density0.50.81.20.9-0.8-0.80.51.1-1.0-1.01.01.0-1.0-1.01.01.0-0.2-0.8-0.1-1.01.1-0.90.6
Bone: cortical apparent density0.40.53.4-0.40.50.5-0.50.50.20.1-0.1-0.10.10.0-0.0-0.01.4-0.31.4-0.50.2-0.51.9
Bone: cortical area2.43.66.11.8-1.8-1.81.62.5-2.0-2.02.02.0-2.0-2.12.12.1-0.7-2.0-0.7-2.32.1-2.00.8
Bone: cortical porosity0.50.50.9-0.80.80.8-0.7-0.90.80.8-0.8-0.80.80.8-0.8-0.80.60.60.60.8-0.60.60.1
Bone: cortical porosity0.00.00.1-0.10.10.10.1-0.30.10.1-0.1-0.10.10.1-0.1-0.10.1-0.00.10.20.0-0.0-0.0
Bone: cortical thickness0.91.43.40.9-0.8-0.90.71.9-1.1-1.21.21.2-1.2-1.21.31.30.3-1.40.3-1.61.4-1.41.5
Bone: cortical thickness0.10.20.6-0.30.40.4-0.50.20.30.3-0.3-0.30.30.2-0.2-0.30.80.10.8-0.1-0.20.10.8
Bone: cortical tissue density0.30.43.0-0.50.60.6-0.60.40.30.2-0.2-0.20.20.1-0.1-0.11.4-0.21.4-0.30.1-0.31.7
Condit. Reinf. active minus inactive responses0.60.61.00.8-0.7-0.80.81.0-0.8-0.80.80.9-0.9-0.90.91.0-0.3-0.9-0.3-0.80.9-0.80.4
Condit. Reinf. active-inactive response ratio0.60.60.8-0.90.90.9-0.9-0.40.80.8-0.8-0.80.80.8-0.8-0.70.90.60.90.6-0.80.70.6
Condit. Reinf. active responses3.03.64.91.9-1.9-1.91.82.2-2.0-2.02.12.1-2.1-2.12.12.2-1.0-2.1-0.9-2.12.1-2.00.5
Condit. Reinf. inactive responses3.64.36.62.0-2.0-2.01.82.6-2.2-2.22.22.2-2.2-2.32.32.4-0.9-2.1-0.8-2.42.5-2.20.8
Incentive salience index mean4.55.56.82.5-2.5-2.52.52.4-2.5-2.52.52.5-2.5-2.52.52.6-1.8-2.4-1.8-2.32.4-2.2-0.2
Condit. Reinf. lever presses10.714.317.54.1-4.2-4.24.13.4-4.1-4.04.04.0-4.0-4.03.94.0-3.5-3.6-3.5-3.43.6-3.3-1.4
Condit. Reinf. active minus inactive responses0.70.81.21.0-0.9-0.90.81.1-1.0-1.01.01.0-1.0-1.01.01.0-0.5-0.9-0.5-0.90.9-1.00.2
Condit. Reinf. active-inactive response ratio0.10.10.40.2-0.2-0.20.00.7-0.3-0.30.40.4-0.3-0.30.40.50.1-0.10.1-0.40.5-0.30.5
Condit. Reinf. active responses2.33.23.91.9-1.9-1.91.81.9-2.0-2.02.02.0-2.0-2.02.01.9-1.3-1.8-1.3-1.81.8-1.8-0.1
Condit. Reinf. inactive responses3.24.06.12.0-2.0-2.02.02.1-2.2-2.22.12.1-2.2-2.22.22.0-0.9-2.5-0.9-2.12.1-2.30.5
Condit. Reinf. lever presses2.33.15.31.7-1.6-1.61.42.3-1.9-1.91.91.9-1.9-2.02.01.9-0.3-2.0-0.3-2.12.2-1.91.1
Condit. Reinf. lever reinforcers received2.73.84.52.1-2.1-2.11.92.1-2.1-2.12.12.1-2.1-2.12.12.1-1.4-2.0-1.3-1.92.0-1.9-0.1
Conditioned reinforcement - actives0.30.31.60.0-0.3-0.31.1-0.4-0.4-0.40.40.4-0.4-0.40.40.3-0.1-1.3-0.1-0.00.4-1.10.2
Conditioned reinforcement - inactives0.20.21.0-0.20.10.11.0-1.00.10.1-0.2-0.20.20.1-0.2-0.3-0.1-1.0-0.10.5-0.5-0.7-0.3
Conditioned locomotion0.30.30.60.5-0.6-0.60.80.3-0.6-0.60.60.6-0.6-0.60.60.4-0.5-0.8-0.5-0.10.4-0.7-0.3
Patch foraging indifference point 0 sec0.81.27.50.9-1.0-1.01.0-0.3-0.5-0.40.40.3-0.3-0.30.20.2-2.40.3-2.40.4-0.20.7-2.7
Patch foraging indifference point AUC7.89.011.03.2-3.3-3.32.83.0-3.3-3.33.33.3-3.3-3.23.23.3-2.6-2.6-2.5-2.73.2-2.6-0.7
Delay disc. indifference point, 0s delay1.31.42.5-1.01.11.1-0.9-1.61.31.3-1.3-1.31.31.3-1.3-1.40.31.30.31.5-1.41.4-0.7
Delay disc. indifference point, 16s delay1.31.32.7-0.60.70.8-0.7-1.61.11.1-1.1-1.11.21.2-1.2-1.3-0.41.4-0.51.5-1.61.4-1.5
Delay disc. indifference point, 2s delay0.10.10.30.00.00.00.1-0.0-0.1-0.10.10.1-0.1-0.10.20.10.4-0.30.4-0.20.3-0.50.6
Delay disc. indifference point, 24s delay0.10.10.6-0.30.30.3-0.7-0.20.40.4-0.4-0.40.40.4-0.4-0.30.20.70.20.3-0.30.50.0
Delay disc. indifference point, 4s delay0.10.10.5-0.20.30.3-0.6-0.10.30.3-0.3-0.30.30.3-0.3-0.40.20.70.20.3-0.30.6-0.1
Delay disc. indifference point, 8s delay0.00.00.20.2-0.1-0.1-0.30.4-0.1-0.10.10.1-0.1-0.10.10.0-0.20.4-0.2-0.10.00.3-0.2
Indifference point function ln k2.53.54.6-1.92.02.0-1.8-1.92.02.0-2.1-2.12.02.0-2.0-2.11.41.71.41.9-2.01.80.1
Indifference point function log k2.53.54.6-1.92.02.0-1.8-1.92.02.0-2.1-2.12.02.0-2.0-2.11.41.71.41.9-2.01.80.1
Patch foraging total patch changes 0 sec0.91.56.71.3-1.3-1.31.40.1-0.9-0.80.80.7-0.7-0.70.60.6-2.5-0.1-2.50.00.20.2-2.6
Patch foraging total patch changes 12 sec2.02.63.21.8-1.8-1.81.51.8-1.8-1.81.81.8-1.8-1.81.81.8-1.3-1.4-1.3-1.51.6-1.4-0.3
Patch foraging total patch changes 18 sec0.70.91.61.1-1.1-1.11.01.0-1.0-1.01.01.0-1.0-0.90.91.0-1.3-0.4-1.3-0.60.8-0.3-0.8
Patch foraging total patch changes 24 sec2.32.83.91.8-1.9-2.01.81.4-1.8-1.81.81.8-1.7-1.71.71.8-2.0-1.3-2.0-1.11.5-1.1-1.1
Patch foraging total patch changes 6 sec2.63.97.62.4-2.3-2.32.11.4-2.0-2.02.01.9-1.9-1.91.81.9-2.8-1.2-2.8-1.11.6-1.0-2.0
Patch foraging time to switch 0 sec2.64.05.4-2.12.32.3-2.0-1.92.12.1-2.1-2.12.12.0-2.0-2.12.31.42.31.6-2.01.31.3
Patch foraging water rate 0 sec1.62.64.81.7-1.9-1.91.71.4-1.6-1.61.61.6-1.6-1.51.51.6-2.2-0.9-2.2-1.31.3-0.8-1.5
Patch foraging water rate 12 sec0.10.10.60.2-0.2-0.20.20.1-0.1-0.10.10.1-0.1-0.10.0-0.1-0.60.0-0.60.0-0.10.1-0.7
Patch foraging water rate 18 sec0.30.41.00.4-0.5-0.50.50.6-0.6-0.60.60.6-0.6-0.70.70.50.0-0.80.0-0.80.7-1.00.5
Patch foraging water rate 24 sec0.20.31.8-0.40.30.3-0.40.50.00.0-0.00.0-0.0-0.00.10.11.0-0.11.0-0.50.4-0.41.4
Patch foraging water rate 6 sec0.81.12.11.0-1.1-1.11.40.9-1.1-1.11.11.1-1.1-1.11.10.9-0.9-1.5-0.9-1.10.8-1.3-0.3
Seeking ratio, delayed vs. immediate footshock3.43.95.82.1-2.0-2.01.92.4-2.1-2.12.12.1-2.1-2.12.12.1-1.1-2.2-1.1-2.32.0-2.00.3
Distance traveled before self-admin5.45.79.12.8-2.7-2.73.01.9-2.5-2.52.52.4-2.4-2.42.42.3-2.5-2.5-2.5-2.01.7-2.2-1.2
Distance traveled after self-admin1.11.33.70.9-1.0-1.01.50.9-1.1-1.11.11.1-1.1-1.21.11.1-0.3-1.9-0.3-1.21.0-1.70.6
Extensor digitorum longus weight4.718.722.24.7-4.7-4.74.74.6-4.7-4.74.74.6-4.6-4.64.64.6-3.5-4.5-3.4-4.23.8-4.0-0.5
Bone: elastic displacement4.95.68.2-2.62.72.7-2.9-1.62.52.5-2.5-2.42.42.4-2.4-2.32.62.42.51.9-2.12.21.4
Bone: elastic work2.43.18.4-2.02.02.0-2.2-0.31.61.5-1.5-1.51.41.4-1.3-1.22.91.12.90.7-0.90.92.7
Bone: endosteal estimation1.12.43.61.7-1.8-1.81.81.2-1.6-1.61.61.6-1.6-1.51.51.6-1.9-1.2-1.9-1.31.2-1.1-1.2
Bone: endosteal perimeter1.22.54.61.8-1.9-1.81.81.2-1.6-1.61.61.5-1.5-1.51.51.5-2.2-1.0-2.2-1.21.1-1.0-1.5
Epididymis fat weight0.61.41.91.4-1.3-1.31.21.4-1.2-1.21.21.2-1.2-1.21.21.2-1.2-0.9-1.2-1.20.9-0.8-0.5
Delta time in closed arm before/after self-admin2.62.55.11.4-1.4-1.40.82.3-1.6-1.61.71.7-1.7-1.71.81.9-0.2-1.5-0.2-2.12.0-1.51.2
Delta time in open arm before/after self-admin0.50.51.4-0.60.50.5-0.1-1.20.70.7-0.7-0.70.70.7-0.8-0.9-0.10.6-0.21.1-1.00.5-0.8
Diff in mean of infusions in LGA sessions0.10.10.3-0.20.30.3-0.30.30.20.2-0.2-0.20.20.2-0.2-0.10.30.50.3-0.0-0.10.50.3
Delay discount exponential model param0.50.51.40.3-0.5-0.50.80.7-0.6-0.60.70.7-0.7-0.70.70.80.1-1.20.2-0.90.9-1.10.8
Extinction: sum of active levers before priming1.91.93.2-1.51.41.4-1.2-1.81.51.5-1.5-1.51.51.5-1.5-1.60.91.20.91.4-1.51.0-0.1
Active lever presses in extinction session 60.80.81.9-0.80.80.7-1.2-0.90.90.9-0.8-0.80.90.9-0.9-0.80.21.40.21.1-0.71.4-0.4
Bone: final force1.42.23.01.6-1.6-1.61.41.7-1.6-1.61.61.6-1.6-1.61.61.7-1.0-1.4-1.0-1.51.4-1.40.0
Bone: final moment1.01.72.61.3-1.3-1.31.11.6-1.4-1.41.41.4-1.4-1.41.41.5-0.7-1.3-0.7-1.41.3-1.20.3
Food consumed during 24 hour testing period1.01.21.81.2-1.3-1.31.31.0-1.2-1.11.21.1-1.1-1.11.11.2-1.2-1.1-1.2-1.00.7-1.0-0.7
Glucose1.11.72.11.4-1.4-1.41.31.4-1.4-1.41.41.4-1.4-1.41.41.4-1.2-1.0-1.2-1.41.2-1.1-0.4
Heart weight0.71.01.71.3-1.2-1.20.91.1-1.1-1.11.01.0-1.0-1.01.00.9-1.2-0.7-1.2-0.90.7-0.6-0.7
Delay discount hyperbolic model param0.40.41.30.3-0.4-0.40.70.6-0.6-0.60.60.6-0.6-0.60.70.70.2-1.10.2-0.80.8-1.00.7
Intermittent access intake day 1-15 change1.01.02.50.6-0.6-0.60.61.6-0.9-0.90.90.9-0.9-1.01.01.10.4-1.10.4-1.41.1-1.11.3
Intermittent access intake escalation1.41.43.21.0-0.9-0.90.81.8-1.2-1.21.21.2-1.2-1.21.31.40.0-1.20.0-1.61.4-1.21.1
Intermittent access intake escalation 21.71.73.50.8-0.9-0.91.01.7-1.2-1.31.21.3-1.3-1.31.31.40.4-1.60.4-1.81.5-1.91.6
Intermitt. access day 1 inactive lever presses0.70.81.31.1-1.0-0.90.81.1-0.9-0.90.90.9-0.9-0.90.91.0-0.8-0.7-0.8-0.90.7-0.8-0.2
Intermitt. access day 15 inactive lever presses0.10.10.50.6-0.3-0.30.60.1-0.2-0.20.10.1-0.1-0.10.10.0-0.7-0.2-0.7-0.1-0.3-0.1-0.7
Intermitt. access escalation Index1.31.22.11.5-1.3-1.31.10.9-1.1-1.11.11.1-1.1-1.01.01.0-1.4-0.6-1.4-1.00.7-0.7-1.0
Intermittent access day 1 total infusions0.80.92.8-0.60.60.6-0.5-1.70.80.9-0.9-0.90.90.9-1.0-1.2-0.40.7-0.41.5-1.21.0-1.3
Intermittent access day 15 total infusions0.30.40.80.6-0.6-0.60.70.4-0.6-0.60.60.6-0.6-0.60.60.6-0.5-0.9-0.5-0.40.5-0.6-0.1
Intermittent access terminal intake (last 3 days)0.60.71.90.7-0.9-0.91.40.2-0.9-0.90.80.8-0.8-0.80.80.7-0.7-1.3-0.7-0.50.6-1.2-0.3
Intermittent access total infusions0.50.61.20.8-0.9-0.91.10.2-0.8-0.80.80.8-0.8-0.80.70.6-0.9-1.1-0.9-0.30.5-0.8-0.6
Intermittent access day 1 locomotion1.41.53.0-1.11.01.0-1.1-1.71.21.2-1.2-1.21.21.3-1.3-1.40.11.30.11.7-1.31.5-1.0
Intermittent access day 15 total locomotion0.90.91.5-0.90.90.9-0.9-1.01.01.0-1.0-1.11.01.0-1.1-1.20.41.00.41.2-1.11.0-0.3
Intermittent access total locomotion0.60.71.0-1.00.90.9-0.8-1.00.90.9-0.9-0.90.90.8-0.8-1.00.80.50.80.9-0.80.50.2
Intermittent access standard deviation0.40.51.10.5-0.6-0.60.70.8-0.7-0.70.60.7-0.7-0.70.70.7-0.1-1.0-0.1-0.80.6-1.10.5
Left kidney weight0.51.53.01.5-1.4-1.41.50.8-1.2-1.11.21.1-1.1-1.11.11.0-1.7-1.1-1.7-0.90.6-0.8-1.3
Right kidney weight0.10.20.90.5-0.4-0.40.50.0-0.2-0.20.20.2-0.1-0.10.10.1-0.9-0.1-0.9-0.0-0.20.1-0.9
Cocaine induced anxiety1.01.12.6-1.21.11.1-0.6-1.61.11.1-1.2-1.21.21.2-1.2-1.20.70.60.61.2-1.20.5-0.1
Post-drug Anxiety0.50.50.90.8-0.8-0.80.90.4-0.7-0.70.70.7-0.7-0.70.70.6-0.7-0.9-0.7-0.60.5-0.8-0.3
Baseline Anxiety1.51.53.81.2-1.1-1.20.61.9-1.3-1.31.41.4-1.4-1.41.41.5-0.4-0.9-0.3-1.61.6-0.80.6
Tail length2.88.612.33.5-3.3-3.32.93.1-3.2-3.13.13.1-3.1-3.13.13.0-2.8-2.7-2.8-2.82.7-2.1-1.2
Length with tail0.93.45.22.3-2.1-2.11.91.8-1.9-1.91.91.9-1.9-1.81.81.7-2.3-1.5-2.3-1.51.3-1.0-1.4
Length without tail0.40.91.3-1.10.90.9-0.8-1.01.01.0-1.0-1.01.11.1-1.1-1.10.41.00.41.2-1.11.0-0.3
Times rat made contact with spout0.40.51.00.6-0.5-0.50.71.0-0.7-0.70.70.7-0.7-0.70.70.80.1-0.90.1-0.90.4-0.90.8
Lifetime Intake0.80.92.31.0-1.0-1.01.5-0.4-0.8-0.80.70.7-0.7-0.70.60.4-1.5-1.2-1.50.10.1-0.8-1.5
Liver weight, left0.61.01.21.1-1.0-1.01.11.1-1.0-1.01.01.0-1.0-1.01.01.1-0.8-1.0-0.8-1.10.8-1.1-0.1
Liver weight, right0.00.10.4-0.10.10.10.1-0.70.20.2-0.2-0.20.20.2-0.2-0.3-0.20.1-0.20.4-0.6-0.0-0.3
Locomotor activity0.00.00.10.1-0.2-0.20.20.1-0.2-0.20.10.1-0.1-0.20.10.1-0.1-0.1-0.1-0.20.1-0.3-0.0
Locomotor testing distance0.10.21.40.1-0.2-0.20.3-0.60.00.1-0.1-0.10.10.1-0.2-0.3-0.80.2-0.80.5-0.40.2-1.2
Locomotor testing rearing0.91.42.71.3-1.4-1.31.60.6-1.3-1.21.21.2-1.2-1.21.11.0-1.4-1.3-1.4-0.80.6-1.3-0.8
Locomotion in novel chamber0.10.20.8-0.60.30.3-0.60.10.20.2-0.1-0.10.10.1-0.10.20.70.20.7-0.00.2-0.00.9
Locomotion in novel chamber post-restriction1.72.14.00.8-1.0-1.10.81.9-1.4-1.41.51.5-1.5-1.51.61.70.3-1.60.3-1.82.0-1.71.6
Fecal boli incidents, locomotor time 11.01.12.2-1.31.11.1-1.5-0.21.11.1-1.0-1.01.01.0-1.0-0.81.01.41.00.9-0.61.40.6
Change in fecal boli incidents, locomotor task1.21.12.41.3-1.3-1.31.30.6-1.1-1.11.01.0-1.0-1.01.00.9-1.5-0.7-1.5-0.70.8-0.5-1.2
Time >=10cm from walls, locomotor time 10.20.21.10.5-0.3-0.30.3-0.1-0.1-0.00.10.0-0.00.0-0.0-0.1-0.80.4-0.90.2-0.30.5-1.0
Bouts of movement, locomotor time 11.81.93.2-1.61.51.5-1.4-1.81.51.5-1.5-1.51.51.4-1.5-1.61.31.01.31.3-1.21.00.3
Total resting periods, locomotor time 12.32.63.6-1.91.81.8-1.8-1.71.71.7-1.7-1.71.61.6-1.6-1.71.81.21.81.3-1.31.10.8
Rest time, locomotor task time 12.02.27.0-1.91.71.6-1.8-0.51.21.2-1.2-1.11.11.0-1.0-0.82.60.72.70.5-0.10.32.5
Distance moved, locomotor task time 12.32.55.92.1-1.9-1.82.00.7-1.5-1.51.51.4-1.4-1.41.31.3-2.4-1.1-2.4-0.90.8-0.9-1.9
Vertical activity count, locomotor time 11.61.75.61.5-1.5-1.51.70.1-1.1-1.11.01.0-1.0-0.90.90.7-2.4-0.7-2.4-0.40.2-0.4-2.3
Time >=10cm from walls, locomotor time 20.10.10.20.4-0.4-0.40.20.4-0.3-0.30.30.3-0.3-0.30.30.3-0.50.0-0.5-0.20.2-0.1-0.3
Bouts of movement, locomotor time 20.50.50.90.7-0.8-0.80.70.6-0.8-0.80.80.8-0.8-0.80.80.6-0.5-0.9-0.5-0.70.8-0.8-0.1
Total resting periods, locomotor time 20.20.20.40.3-0.4-0.40.40.3-0.5-0.50.40.5-0.5-0.50.50.2-0.1-0.7-0.1-0.40.5-0.50.1
Rest time, locomotor task time 20.91.01.7-1.31.11.1-1.0-1.11.01.0-1.0-1.01.01.0-0.9-0.91.20.81.21.0-0.60.70.6
Distance moved, locomotor task time 20.60.71.60.8-0.7-0.70.61.3-0.8-0.80.80.8-0.8-0.90.91.0-0.1-0.8-0.1-1.10.9-1.00.6
Vertical activity count, locomotor time 20.60.71.10.9-0.9-0.90.71.1-0.8-0.80.80.8-0.8-0.80.80.8-0.9-0.5-0.9-0.80.6-0.5-0.5
Light reinforcement 11.62.910.12.0-2.0-1.92.10.4-1.4-1.31.31.2-1.2-1.21.10.9-3.2-0.9-3.2-0.6-0.0-0.6-3.1
Light reinforcement 21.41.811.61.2-1.2-1.11.3-1.0-0.5-0.50.50.4-0.4-0.30.20.0-2.8-0.0-2.80.6-0.60.3-3.4
Bone: marrow area1.22.53.31.7-1.8-1.81.81.4-1.7-1.71.71.7-1.6-1.61.61.7-1.8-1.3-1.8-1.41.3-1.3-1.0
Bone: maximum diameter2.44.45.62.1-2.2-2.22.02.3-2.2-2.22.32.3-2.3-2.32.32.4-1.4-2.0-1.4-2.22.3-2.10.1
Bone: maximum force3.15.36.72.4-2.4-2.42.22.6-2.5-2.52.52.5-2.5-2.52.52.6-1.5-2.3-1.4-2.42.4-2.30.2
Bone: maximum moment2.34.05.72.0-2.0-2.01.92.4-2.2-2.22.22.2-2.2-2.22.22.3-1.1-2.1-1.0-2.22.2-2.00.5
Mean time between licks in bursts0.30.40.6-0.70.70.7-0.8-0.50.70.7-0.7-0.70.70.7-0.7-0.60.60.80.60.7-0.70.60.3
Mean num. licks in bursts2.63.13.7-1.81.91.9-1.9-1.81.91.9-1.9-1.91.91.9-1.9-1.91.41.91.41.7-1.91.70.2
Cd content in liver0.91.01.80.8-0.8-0.90.81.0-1.0-1.11.11.1-1.1-1.11.11.1-0.1-1.1-0.1-1.21.0-1.30.8
Co content in liver1.11.32.0-1.01.01.0-0.9-1.31.21.2-1.2-1.21.21.2-1.3-1.20.21.10.21.4-1.41.4-0.8
Cu content in liver0.81.02.0-1.21.21.2-1.1-0.71.01.0-1.0-1.01.01.0-0.9-0.81.40.81.40.6-0.60.51.0
Fe content in liver0.60.74.60.7-0.7-0.60.8-0.5-0.3-0.20.20.2-0.2-0.10.10.0-1.70.0-1.70.4-0.40.4-2.2
K content in liver0.30.31.0-0.30.30.3-0.5-0.60.50.5-0.5-0.50.50.6-0.6-0.5-0.31.0-0.30.7-0.51.0-0.8
Mg content in liver0.80.82.1-0.90.80.8-1.1-0.70.90.9-0.9-0.90.90.9-0.9-0.80.31.40.31.0-0.51.4-0.3
Mn content in liver0.20.20.70.1-0.2-0.20.30.8-0.4-0.40.40.4-0.4-0.40.50.50.4-0.80.4-0.60.9-0.40.7
Na content in liver1.11.11.4-1.21.21.2-1.0-1.21.21.2-1.2-1.21.21.2-1.2-1.20.80.90.81.1-1.21.00.1
Rb content in liver4.04.96.3-2.32.32.3-2.2-2.22.42.4-2.4-2.42.42.4-2.4-2.31.32.41.32.4-2.52.4-0.1
Se content in liver1.92.34.01.4-1.4-1.41.41.8-1.6-1.61.61.6-1.6-1.71.71.6-0.4-1.9-0.4-1.82.0-1.80.7
Sr content in liver0.40.41.20.7-0.6-0.60.50.5-0.7-0.70.70.7-0.7-0.70.70.7-0.4-0.7-0.4-0.61.1-0.40.1
Zn content in liver0.20.20.8-0.0-0.0-0.0-0.20.6-0.2-0.20.30.3-0.3-0.30.30.50.6-0.10.6-0.50.8-0.30.9
Bone: minimum diameter0.00.10.2-0.30.20.2-0.40.10.20.1-0.1-0.10.10.1-0.1-0.00.40.30.4-0.00.20.20.5
Time in familiar zone, hab. session 11.21.16.4-0.91.01.0-1.10.30.50.5-0.5-0.40.40.3-0.3-0.32.20.02.2-0.20.5-0.22.5
Time in novel zone, hab. session 12.12.05.1-0.80.70.8-0.6-1.91.21.3-1.3-1.31.31.4-1.4-1.4-0.91.7-0.91.9-2.11.8-2.3
Total zone transitions, hab. session 10.00.00.10.1-0.1-0.1-0.20.1-0.1-0.10.10.1-0.1-0.10.10.10.00.20.0-0.10.4-0.10.1
Total locomotion distance, hab. session 10.50.72.00.4-0.4-0.40.11.2-0.7-0.70.80.8-0.8-0.80.90.90.6-0.70.6-1.11.3-1.01.4
Locomotion velocity, hab. session 11.62.34.41.3-1.3-1.31.01.9-1.6-1.61.61.6-1.6-1.71.71.7-0.2-1.4-0.1-1.92.1-1.71.1
Time in familiar zone, hab. session 20.90.93.1-1.11.11.1-1.3-0.10.80.8-0.8-0.70.70.7-0.6-0.61.70.71.70.2-0.10.31.7
Time in novel zone, hab. session 21.61.63.4-0.80.80.8-0.4-1.81.21.2-1.2-1.21.31.3-1.3-1.4-0.51.1-0.61.6-1.91.6-1.8
Total zone transitions, hab. session 20.60.81.91.0-1.1-1.11.00.6-0.9-0.90.90.8-0.8-0.80.80.9-1.4-0.4-1.4-0.60.7-0.5-1.1
Total locomotion distance, hab. session 20.81.11.41.1-1.1-1.11.01.1-1.1-1.11.11.1-1.1-1.11.11.2-0.7-0.9-0.7-1.11.2-1.1-0.0
Locomotion velocity, hab. session 21.11.41.91.2-1.2-1.31.01.3-1.3-1.31.31.3-1.3-1.31.31.4-0.8-0.9-0.8-1.31.4-1.30.1
Novel to familiar place preference ratio3.63.76.2-1.71.71.7-1.5-2.52.02.0-2.0-2.12.12.1-2.1-2.10.32.10.32.4-2.52.3-1.3
Novelty place preference4.84.97.7-2.12.02.1-1.8-2.72.32.4-2.4-2.42.42.4-2.4-2.40.72.40.72.6-2.82.5-1.1
Time in novel zone, NPP test5.86.09.3-2.32.32.3-2.0-3.02.62.6-2.6-2.62.72.7-2.7-2.70.82.60.72.9-3.02.8-1.2
Total zone transitions, NPP test0.81.12.71.2-1.3-1.31.10.7-1.0-1.01.01.0-1.0-1.00.90.9-1.7-0.5-1.7-0.70.5-0.5-1.4
Total locomotion distance, NPP test1.92.53.81.9-1.9-1.91.61.2-1.7-1.71.71.6-1.6-1.61.61.5-2.0-1.1-2.0-1.31.4-1.1-1.3
Locomotion velocity, NPP test2.33.34.42.1-2.1-2.11.71.6-2.0-1.91.91.9-1.9-1.91.91.9-1.9-1.3-1.9-1.71.7-1.5-1.0
Intraocular pressure2.23.14.22.0-2.0-2.01.91.3-1.9-1.91.91.8-1.8-1.81.81.7-2.0-1.6-2.0-1.41.6-1.4-1.1
Delta distance traveled before/after self-admin0.40.50.9-0.90.80.8-0.5-0.80.70.7-0.7-0.70.70.7-0.7-0.70.90.10.90.4-0.60.10.7
Delta ambulatory time before/after self-admin1.31.42.3-1.51.41.4-1.0-1.31.31.3-1.3-1.31.31.2-1.2-1.21.40.61.40.9-1.10.50.8
Parametrial fat weight0.30.51.00.9-0.8-0.80.51.0-0.7-0.70.70.7-0.6-0.60.60.7-0.9-0.3-0.9-0.70.4-0.2-0.6
Pavlov. Cond. lever latency7.99.912.2-3.43.43.4-3.5-2.93.43.4-3.4-3.33.33.3-3.3-3.32.73.32.73.0-3.13.00.8
Pavlov. Cond. magazine entry latency0.40.61.00.8-0.8-0.80.61.0-0.8-0.80.80.8-0.8-0.80.80.9-0.4-0.6-0.4-0.80.9-0.70.2
Pavlov. Cond. change in total contacts2.93.13.91.9-1.9-1.92.01.8-1.9-1.91.91.9-1.9-1.91.81.9-1.6-1.8-1.6-1.71.6-1.6-0.5
Pavlov. Cond. index score3.44.45.32.2-2.2-2.22.12.3-2.3-2.32.32.3-2.3-2.32.32.3-1.5-2.1-1.4-2.12.2-2.0-0.0
Pavlov. Cond. latency score3.14.04.82.1-2.1-2.12.12.1-2.2-2.22.22.2-2.2-2.22.12.2-1.4-2.1-1.4-2.02.2-1.9-0.1
Pavlov. Cond. lever contacts5.66.67.72.7-2.8-2.82.82.6-2.8-2.82.82.7-2.7-2.72.72.8-2.1-2.7-2.1-2.52.6-2.4-0.5
Pavlov. Cond. magazine entry number0.91.11.8-1.11.11.1-0.9-1.41.11.1-1.1-1.11.11.1-1.1-1.20.60.90.61.1-1.11.0-0.2
Pavlov. Cond. intertrial magazine entries0.20.30.50.5-0.5-0.50.50.5-0.6-0.60.60.6-0.6-0.60.60.6-0.2-0.7-0.2-0.60.7-0.60.2
Pavlov. Cond. lever-magazine prob. diff.3.13.95.12.0-2.0-2.01.92.3-2.1-2.12.12.1-2.1-2.12.12.2-1.1-2.0-1.1-2.12.2-2.00.3
Pavlov. Cond. response bias3.34.14.82.2-2.2-2.22.02.2-2.2-2.22.22.2-2.2-2.22.22.2-1.5-1.9-1.5-2.02.1-1.9-0.2
Pavlov. Cond. lever latency2.73.65.5-1.71.71.7-1.5-2.32.02.0-2.0-2.12.12.1-2.1-2.00.32.20.32.3-2.32.2-1.2
Pavlov. Cond. magazine entry latency0.30.40.7-0.50.70.7-0.7-0.40.60.6-0.6-0.60.60.6-0.6-0.60.80.40.80.4-0.60.30.6
Pavlov. Cond. change in total contacts1.01.33.70.7-0.6-0.60.21.8-1.0-1.11.01.1-1.1-1.21.21.10.8-1.10.8-1.51.4-1.41.9
Pavlov. Cond. index score0.30.41.80.3-0.2-0.20.01.0-0.5-0.50.50.5-0.6-0.60.60.60.7-0.70.7-0.80.8-0.81.3
Pavlov. Cond. latency score0.50.62.20.4-0.3-0.30.11.1-0.6-0.60.60.7-0.7-0.70.80.70.7-0.90.7-1.00.9-0.91.5
Pavlov. Cond. lever contacts1.31.82.91.2-1.2-1.21.01.6-1.4-1.41.41.5-1.5-1.51.51.4-0.3-1.5-0.2-1.61.7-1.40.8
Pavlov. Cond. magazine entry number0.30.42.7-0.0-0.2-0.10.3-0.70.20.2-0.2-0.20.20.3-0.3-0.3-1.10.4-1.10.6-0.40.6-1.6
Pavlov. Cond. intertrial magazine entries0.40.50.70.7-0.8-0.80.80.6-0.7-0.70.80.7-0.7-0.70.70.8-0.8-0.6-0.8-0.60.6-0.6-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.42.00.3-0.2-0.2-0.01.0-0.5-0.50.50.5-0.5-0.60.60.60.8-0.70.8-0.90.8-0.81.4
Pavlov. Cond. response bias0.60.81.30.7-0.7-0.70.51.2-0.9-0.90.90.9-1.0-1.01.00.90.2-1.10.2-1.11.2-1.11.0
Time in closed arm before self-admin2.93.24.3-2.11.91.9-1.7-1.91.91.9-2.0-1.91.91.9-1.9-2.01.31.81.31.9-1.71.70.1
Time in closed arm after self-admin0.20.20.6-0.50.50.5-0.70.10.40.3-0.3-0.30.30.3-0.3-0.10.80.30.8-0.00.00.30.8
Time in open arm before self-admin2.52.74.12.0-1.9-1.91.81.3-1.7-1.71.71.7-1.7-1.71.61.6-2.0-1.4-2.0-1.21.2-1.0-1.2
Time in open arm after self-admin1.21.32.71.3-1.4-1.31.50.4-1.2-1.11.11.1-1.1-1.11.00.9-1.6-1.0-1.6-0.50.6-0.9-1.3
Bone: periosteal estimation1.73.44.21.9-2.0-2.01.92.0-2.0-2.02.02.0-2.0-2.02.02.1-1.5-1.7-1.5-1.91.8-1.7-0.3
Bone: periosteal perimeter0.61.01.91.1-1.2-1.21.20.8-1.0-1.01.01.0-0.9-0.90.91.0-1.4-0.7-1.4-0.80.6-0.6-1.0
Bone: post-yield work1.62.23.01.6-1.7-1.71.61.0-1.5-1.51.51.5-1.5-1.51.51.4-1.7-1.1-1.7-1.11.4-1.3-1.1
Progressive ratio test 1 active lever presses0.50.52.00.5-0.5-0.41.2-1.1-0.2-0.20.10.1-0.1-0.10.1-0.3-1.1-1.1-1.10.5-0.4-0.6-1.4
Progressive ratio test 1 breakpoint0.50.61.90.7-0.6-0.61.3-0.9-0.4-0.40.30.3-0.3-0.30.3-0.1-1.2-1.2-1.20.3-0.2-0.7-1.4
Progressive ratio test 1 inactive lever presses1.01.14.81.1-1.0-0.91.6-0.7-0.6-0.50.50.4-0.4-0.40.30.0-1.9-0.8-2.00.4-0.3-0.5-2.2
Progressive ratio test 2 active lever presses0.50.52.30.1-0.2-0.11.0-1.50.10.1-0.2-0.20.20.2-0.3-0.5-1.0-0.5-1.01.0-0.8-0.1-1.5
Progressive ratio test 2 breakpoint0.50.62.7-0.10.10.10.7-1.60.40.4-0.4-0.50.50.5-0.5-0.8-0.8-0.2-0.81.2-1.00.1-1.5
Progressive ratio test 2 inactive lever presses0.30.31.30.6-0.6-0.61.1-0.2-0.5-0.50.40.4-0.4-0.50.40.3-0.8-0.9-0.80.20.1-0.8-0.6
Incentive Sensitization - Responses0.20.21.20.2-0.2-0.11.1-0.8-0.0-0.0-0.1-0.10.10.0-0.1-0.2-0.6-0.5-0.60.4-0.5-0.3-0.7
Incentive Sensitization - Breakpoint0.20.20.80.0-0.00.00.9-0.90.10.1-0.2-0.20.20.2-0.2-0.3-0.5-0.3-0.50.6-0.6-0.2-0.7
Sum of active levers in priming session hrs 5-63.93.85.8-1.81.81.8-1.9-2.32.02.1-2.1-2.12.12.1-2.1-2.10.62.20.62.3-2.22.4-0.9
Progressive ratio0.00.10.1-0.10.10.1-0.3-0.30.20.2-0.2-0.20.20.2-0.2-0.2-0.10.3-0.10.3-0.20.4-0.3
Food seeking constrained by brief footshock7.49.114.53.5-3.4-3.43.81.7-3.1-3.13.13.0-3.0-3.02.92.7-3.4-3.2-3.4-2.32.3-2.9-2.0
Seeking ratio, punishment vs. effort2.12.65.01.8-1.8-1.72.20.9-1.7-1.71.71.6-1.6-1.61.61.5-1.5-2.0-1.5-1.31.4-1.8-0.6
Retroperitoneal fat weight0.10.30.5-0.60.60.6-0.70.40.50.5-0.5-0.50.50.4-0.4-0.40.70.60.70.1-0.40.70.6
Reaction time number correct0.10.10.60.3-0.4-0.40.20.2-0.3-0.20.30.2-0.2-0.20.20.2-0.80.2-0.80.0-0.10.0-0.8
Reaction time mean minus median1.01.36.50.4-0.2-0.2-0.11.6-0.7-0.80.80.8-0.8-0.91.01.11.4-0.91.4-1.51.5-1.32.6
Reaction time mean minus median AUC1.21.63.40.9-0.7-0.80.51.5-1.1-1.21.21.2-1.3-1.31.31.40.7-1.40.7-1.71.7-1.61.8
Reaction time num false alarms0.10.10.6-0.10.10.1-0.00.2-0.1-0.10.10.1-0.1-0.10.20.10.6-0.50.6-0.10.4-0.30.8
Reaction time num false alarms AUC0.30.40.90.6-0.6-0.60.70.5-0.6-0.60.60.7-0.7-0.70.70.5-0.2-1.0-0.2-0.50.7-0.70.1
Reaction time trials correct on left0.10.10.60.3-0.4-0.40.20.2-0.3-0.20.30.2-0.2-0.20.20.2-0.80.2-0.80.0-0.10.0-0.8
Reaction time trials on left0.10.10.50.2-0.3-0.30.10.1-0.2-0.10.20.1-0.1-0.10.10.1-0.70.3-0.70.1-0.20.1-0.7
Reaction time mean1.31.85.7-1.31.51.5-1.8-0.31.11.1-1.1-1.01.01.0-0.9-0.82.40.92.40.3-0.40.52.3
Reaction time mean AUC1.62.16.5-1.41.71.7-1.9-0.51.31.2-1.2-1.21.21.1-1.0-0.92.50.92.50.4-0.50.52.4
Median of all reaction times2.43.25.5-1.92.12.1-2.2-1.21.91.8-1.8-1.81.81.7-1.7-1.62.31.62.31.2-1.31.31.6
Reaction time omissions1.31.82.8-1.31.51.5-1.7-0.91.41.4-1.4-1.41.41.4-1.4-1.31.41.41.41.1-1.01.40.7
Reaction time false alarm rate0.10.10.5-0.20.30.3-0.1-0.20.10.1-0.1-0.10.10.1-0.0-0.20.7-0.40.70.00.2-0.20.7
Reaction time premature initiation rate2.33.04.3-1.82.02.0-2.1-0.81.81.8-1.8-1.81.81.7-1.7-1.72.11.62.11.0-1.61.71.3
Reaction time premature initiations1.42.03.1-1.51.61.6-1.8-0.61.51.5-1.5-1.51.51.4-1.4-1.41.51.51.50.9-1.51.50.8
Std. dev. reaction times0.60.96.7-0.30.60.6-1.00.90.10.1-0.1-0.0-0.0-0.10.10.22.0-0.12.0-0.80.6-0.52.6
Reaction time trials completed0.10.10.50.2-0.3-0.30.10.1-0.2-0.10.20.1-0.1-0.10.10.1-0.70.3-0.70.1-0.20.1-0.7
Reaction time trials AUC0.10.10.50.2-0.3-0.30.10.1-0.2-0.10.20.1-0.1-0.10.10.1-0.60.3-0.60.1-0.20.2-0.7
Run reversals in cocaine runway, females0.20.20.8-0.30.10.1-0.40.6-0.1-0.10.20.2-0.2-0.20.20.40.60.00.6-0.40.6-0.20.9
Run reversals in cocaine runway, males0.00.00.1-0.20.20.2-0.2-0.10.20.2-0.2-0.20.20.2-0.2-0.20.30.10.3-0.0-0.10.00.2
Latency to leave start box in cocaine runway0.80.91.61.1-0.9-0.90.91.2-1.0-1.01.01.0-1.0-1.01.01.0-0.4-1.1-0.3-1.10.9-0.90.4
Latency to leave start box in cocaine runway, F0.00.00.20.30.00.0-0.10.30.10.1-0.1-0.10.10.1-0.10.0-0.10.4-0.10.1-0.20.5-0.2
Latency to leave start box in cocaine runway, M1.71.62.71.5-1.4-1.41.60.9-1.3-1.31.31.3-1.3-1.31.31.1-1.3-1.6-1.3-1.11.0-1.2-0.6
Std. dev. time between licks in bursts0.40.50.6-0.80.80.7-0.7-0.80.70.7-0.7-0.70.70.7-0.7-0.70.70.60.70.8-0.60.60.2
Total sessions with >9 infusions0.70.74.20.2-0.3-0.20.9-1.50.10.1-0.2-0.20.20.2-0.3-0.7-1.4-0.4-1.41.1-1.00.2-2.0
Short access day 1 total inactive lever presses2.32.54.91.9-1.8-1.82.20.9-1.6-1.61.51.5-1.5-1.51.51.3-1.9-1.8-1.9-1.10.9-1.7-1.2
Short access day 10 total inactive lever presses0.40.40.90.7-0.6-0.60.50.9-0.7-0.70.60.6-0.6-0.70.60.6-0.4-0.6-0.4-0.90.4-0.90.1
Short access day 1 total infusions1.81.95.21.5-1.5-1.42.3-0.6-1.1-1.00.90.9-0.9-0.90.80.4-2.3-1.7-2.3-0.0-0.0-1.2-2.2
Short access day 10 total infusions0.70.73.11.0-0.9-0.91.0-0.1-0.6-0.60.60.5-0.5-0.50.40.2-1.7-0.6-1.70.2-0.1-0.1-1.8
Short access total infusions0.80.94.50.7-0.7-0.71.4-1.3-0.4-0.30.20.2-0.2-0.20.1-0.3-1.7-1.0-1.70.7-0.6-0.5-2.1
Short access day 1 locomotion0.40.41.4-0.10.20.2-0.4-0.90.40.4-0.5-0.50.50.5-0.6-0.9-0.50.5-0.60.9-0.90.6-1.2
Short access day 10 total locomotion0.80.91.7-1.31.11.1-1.1-0.81.01.0-0.9-0.90.90.9-0.9-0.91.20.71.20.9-0.60.50.7
Short access total locomotion0.20.21.30.2-0.3-0.20.2-0.4-0.1-0.00.0-0.0-0.00.0-0.1-0.4-0.8-0.1-0.80.5-0.30.1-1.1
One hour access (0.3 mA shock)0.40.51.40.5-0.7-0.71.2-0.5-0.5-0.50.50.5-0.5-0.50.50.5-1.1-0.7-1.10.40.4-0.3-1.0
Compulsive drug intake0.20.20.60.3-0.5-0.50.40.4-0.5-0.40.50.5-0.5-0.40.50.7-0.5-0.1-0.5-0.20.70.1-0.2
One hour access (shock baseline)0.30.41.50.6-0.6-0.60.9-0.4-0.4-0.40.40.3-0.3-0.30.30.2-1.2-0.5-1.20.3-0.1-0.3-1.2
Social response proportion1.92.03.1-1.61.61.6-1.8-0.81.51.4-1.4-1.41.41.4-1.4-1.11.71.71.70.9-1.11.31.2
Social responses0.70.91.40.8-1.0-1.00.91.1-1.0-1.01.01.0-1.0-1.01.01.1-0.6-0.7-0.6-1.21.1-0.90.0
Social time0.00.00.2-0.10.10.1-0.30.00.20.2-0.2-0.20.20.2-0.2-0.0-0.10.4-0.10.1-0.10.3-0.1
Soleus weight0.41.17.50.5-0.4-0.40.3-0.90.10.1-0.1-0.20.20.3-0.4-0.4-1.90.9-2.01.0-1.31.0-2.7
Bone: stiffness4.26.78.02.7-2.7-2.72.52.8-2.8-2.82.82.8-2.8-2.82.82.8-1.7-2.7-1.7-2.72.8-2.60.1
Tibialis anterior weight7.324.831.55.6-5.5-5.55.54.7-5.4-5.45.35.3-5.3-5.35.25.1-4.6-4.9-4.6-4.64.2-4.6-1.6
Time to tail flick, vehicle, before self-admin1.71.73.0-1.41.41.4-1.7-1.01.41.4-1.4-1.41.41.4-1.4-1.31.21.51.21.2-1.11.40.3
Time to tail flick, vehicle, after self-admin0.00.00.10.2-0.1-0.00.0-0.0-0.0-0.0-0.0-0.00.00.0-0.0-0.1-0.2-0.1-0.20.0-0.3-0.1-0.2
Time to tail flick, test, before self-admin0.30.30.80.3-0.4-0.40.70.2-0.5-0.50.50.5-0.5-0.50.60.60.0-0.90.0-0.40.7-0.90.4
Time to tail flick, test, after self-admin0.60.61.70.4-0.5-0.6-0.11.3-0.7-0.80.80.8-0.8-0.80.91.00.3-0.40.3-0.91.1-0.61.0
Delta time to tail flick, vehicle, before/after SA0.40.40.80.7-0.7-0.60.90.4-0.6-0.60.60.6-0.6-0.60.60.6-0.5-0.8-0.5-0.50.4-0.7-0.1
Delta time to tail flick, test, before/after SA0.10.10.6-0.20.30.3-0.80.40.20.2-0.2-0.20.20.2-0.2-0.20.40.70.4-0.1-0.20.50.3
Tibia length0.20.53.00.5-0.5-0.50.6-0.4-0.2-0.10.10.1-0.1-0.00.00.0-1.40.2-1.50.4-0.70.5-1.7
Ambulatory time before self-admin3.94.16.62.5-2.3-2.32.61.5-2.1-2.12.02.0-2.0-2.01.91.8-2.5-1.9-2.5-1.51.2-1.5-1.5
Ambulatory time after self-admin0.30.41.10.6-0.6-0.61.00.2-0.6-0.60.60.6-0.6-0.60.50.5-0.6-0.9-0.6-0.40.3-0.7-0.2
Bone: tissue strength0.20.20.50.4-0.4-0.40.30.7-0.5-0.50.50.5-0.5-0.50.50.6-0.1-0.3-0.1-0.50.6-0.50.4
Total heroin consumption0.50.61.7-0.20.40.4-0.2-1.20.70.7-0.7-0.70.70.7-0.8-1.0-0.50.7-0.51.0-1.30.8-1.3
Bone: trabecular number1.11.82.91.3-1.3-1.30.91.6-1.5-1.51.51.5-1.5-1.51.51.4-0.4-1.3-0.3-1.51.7-1.50.7
Bone: trabecular spacing0.10.10.8-0.10.20.2-0.00.40.0-0.00.00.0-0.0-0.00.10.20.6-0.40.6-0.30.2-0.30.9
Bone: trabecular thickness0.10.10.3-0.40.40.4-0.5-0.50.40.4-0.4-0.40.30.4-0.3-0.40.40.50.40.4-0.10.30.2
Bone: trabecular tissue density2.94.05.32.1-2.1-2.12.31.8-2.1-2.12.12.1-2.1-2.12.12.0-1.5-2.3-1.5-2.11.9-2.3-0.3
Water consumed over 24 hours0.91.01.61.0-1.0-1.01.21.2-1.1-1.11.11.1-1.1-1.11.11.1-0.6-1.2-0.6-1.10.8-1.20.2
Number of responses in last shaping day0.91.06.11.1-0.8-0.81.0-0.5-0.4-0.30.20.2-0.2-0.20.1-0.2-2.0-0.0-2.10.5-0.70.2-2.5