Cers4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Cers4 0.29 0.14 6.7e-04 0.09 0.09 0.08 0.07 2.7e-03 2.4e-03 3.4e-03 6.0e-03
2 LHb gene expression Cers4 0.3 0.15 1.1e-03 0.05 0.08 0.08 0.11 2.7e-02 6.5e-03 6.6e-03 1.3e-03
3 pVTA gene expression Cers4 0.42 0.13 1.8e-15 0.17 0.32 0.32 0.31 6.1e-08 2.6e-14 3.0e-14 4.1e-14
4 BLA mRNA stability Cers4 0.15 0.09 5.4e-04 0.07 0.05 -0 0.04 2.1e-04 1.3e-03 8.9e-01 3.4e-03
5 NAcc gene expression Cers4 0.39 0.12 0.0e+00 0.38 0.4 0.41 0.41 1.0e-46 5.5e-50 1.3e-51 3.5e-51
6 Adipose mRNA stability Cers4 0.17 0.08 5.6e-17 0.11 0.11 0.11 0.11 3.9e-12 5.1e-12 4.1e-12 7.2e-12
7 BLA gene expression Cers4 0.37 0.14 0.0e+00 0.34 0.34 0.3 0.34 4.0e-19 4.6e-19 2.5e-16 8.4e-19
8 IL gene expression Cers4 0.35 0.16 4.0e-06 0.22 0.08 0.19 0.01 5.6e-06 5.9e-03 3.2e-05 1.9e-01
9 PL gene expression Cers4 0.52 0.13 0.0e+00 0.5 0.51 0.52 0.52 3.6e-63 1.7e-65 2.4e-66 1.2e-65
10 Brain gene expression Cers4 0.56 0.15 0.0e+00 0.62 0.43 0.62 0.28 1.1e-72 2.7e-43 1.3e-73 7.1e-26
11 Adipose gene expression Cers4 0.45 0.11 0.0e+00 0.34 0.35 0.34 0.35 1.9e-39 3.9e-40 2.0e-39 2.0e-40
12 Adipose alternative polyA NM_001107117.2 0.07 0.04 2.2e-04 0 0.02 -0 0.01 7.7e-02 6.0e-03 3.7e-01 1.7e-02
13 Adipose alternative polyA XM_039089316.1 0.07 0.05 1.6e-04 0.01 0.02 0 0.01 6.8e-02 4.3e-03 2.5e-01 8.9e-03
14 Brain mRNA stability Cers4 0.09 0.05 3.5e-07 0.07 0.08 0.08 0.08 1.0e-06 6.8e-08 1.4e-07 1.5e-07
15 OFC gene expression Cers4 0.57 0.15 1.8e-13 0.32 0.37 0.36 0.38 1.9e-08 1.0e-09 1.4e-09 5.0e-10
16 NAcc alternative polyA XM_039089316.1 0.03 0.02 5.7e-04 0.02 0.02 0 0.02 2.3e-03 1.1e-03 9.4e-02 2.9e-03
17 Brain isoform ratio XM_006248804.4 0.08 0.05 3.1e-05 0.06 0.03 0.04 0.04 4.0e-06 1.7e-03 1.6e-04 1.2e-04
18 Adipose isoform ratio NM_001107117.2 0.13 0.07 8.4e-10 0.06 0.06 0.05 0.06 9.8e-08 2.3e-07 2.3e-06 1.5e-07
19 Adipose isoform ratio XM_006248804.4 0.12 0.06 2.6e-09 0.05 0.04 0.04 0.04 1.7e-06 9.0e-06 1.7e-05 1.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density4.16.914.53.03.03.7-2.8-3.8-3.3-3.4-3.4-3.2-3.13.20.8-0.70.62.40.31.41.4-1.5
Area under the delay curve1.01.02.4-1.3-1.3-0.51.10.2-0.2-0.2-0.2-0.4-0.50.4-1.51.5-1.40.81.21.21.3-1.3
BMI with tail2.06.412.71.61.62.8-1.3-3.4-3.6-3.4-3.4-3.3-3.33.1-0.50.6-0.63.11.12.32.6-2.2
BMI without tail2.14.39.42.62.62.9-2.4-3.1-2.7-2.5-2.4-2.4-2.32.31.1-1.00.91.9-0.31.00.9-0.8
Body weight8.234.374.27.87.68.4-7.1-8.6-7.1-7.1-7.1-6.7-6.36.23.3-3.23.04.6-1.12.11.8-1.5
Weight adjusted by age0.50.61.81.31.00.7-1.1-0.4-0.40.00.00.00.10.41.3-1.31.1-0.6-0.9-0.9-0.30.1
Bone surface4.58.017.43.23.13.9-3.0-4.2-3.6-3.7-3.7-3.5-3.43.30.8-0.70.62.60.31.61.4-1.5
Bone volume4.06.713.32.22.23.3-2.1-3.6-3.4-3.5-3.5-3.4-3.33.3-0.00.1-0.22.80.92.12.0-2.0
Breakpoint value in progressive ratio session1.71.93.40.20.21.2-0.1-1.4-1.7-1.8-1.8-1.7-1.71.7-1.01.0-1.21.51.51.31.5-1.5
Number of licking bursts5.66.612.61.41.4-0.7-1.41.32.42.22.22.42.5-2.73.0-3.03.1-2.9-3.3-3.3-3.53.5
Context. condit. distance diff. score5.56.612.32.12.13.3-2.1-3.5-3.3-3.4-3.4-3.3-3.33.2-0.30.3-0.52.91.42.01.9-1.9
Locomotion velocity, session 10.20.20.5-0.7-0.7-0.40.60.5-0.10.30.30.20.10.0-0.50.5-0.60.20.60.30.6-0.6
Locomotion distance, session 10.60.71.8-1.3-1.3-1.21.31.20.80.90.90.80.7-0.7-0.80.7-0.7-0.10.40.10.2-0.2
Locomotion velocity, session 20.40.51.0-0.3-0.4-0.80.40.90.91.00.91.00.9-1.00.3-0.30.4-0.8-0.6-0.7-0.50.5
Locomotion distance, session 20.81.12.4-0.8-0.9-1.20.71.51.31.51.51.41.4-1.40.1-0.10.1-1.1-0.3-1.0-0.80.7
Locomotion velocity, session 31.01.22.20.40.51.1-0.4-1.2-1.5-1.4-1.4-1.4-1.41.4-0.60.6-0.71.30.91.11.2-1.3
Locomotion distance, session 30.00.00.10.20.20.3-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.00.0-0.10.10.2-0.00.1-0.1
Stereotopy head waving bouts, day 31.11.33.41.81.81.6-1.7-1.3-1.4-0.9-1.0-0.8-0.81.01.3-1.31.00.2-0.6-0.40.2-0.1
Stereotopy head waving duration, day 30.00.00.1-0.1-0.1-0.10.20.1-0.20.1-0.00.10.00.10.0-0.0-0.0-0.1-0.1-0.10.3-0.2
Locomotion velocity, session 70.20.20.8-0.8-0.9-0.70.80.60.30.40.40.30.3-0.3-0.50.5-0.50.10.30.30.2-0.1
Locomotion distance, session 70.00.10.2-0.2-0.20.00.2-0.00.0-0.1-0.1-0.2-0.20.1-0.30.3-0.40.40.40.40.1-0.1
Stereotopy head waving bouts, day 70.30.30.7-0.8-0.8-0.60.80.6-0.10.30.30.30.20.0-0.70.7-0.7-0.10.60.10.6-0.5
Stereotopy head waving duration, day 70.40.41.1-0.9-0.9-1.00.91.00.40.80.80.80.7-0.4-0.40.4-0.4-0.70.2-0.40.2-0.1
Locomotion velocity, session 80.00.10.10.30.20.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.20.1-0.10.20.2-0.1-0.10.1-0.1
Locomotion distance, session 81.21.73.61.21.21.8-1.3-1.9-1.6-1.8-1.8-1.7-1.71.40.00.0-0.01.60.50.90.7-0.7
Degree of sensitization distance0.60.61.3-1.0-1.0-1.20.91.11.20.90.90.90.9-1.0-0.30.3-0.2-0.4-0.2-0.2-0.50.6
Degree of sensitization stereotypy0.20.30.6-0.8-0.7-0.40.70.4-0.10.10.10.0-0.00.2-0.80.8-0.80.10.70.40.6-0.5
Conditioned locomotion0.70.81.7-0.10.10.6-0.0-0.9-0.9-1.1-1.1-1.1-1.10.9-0.80.8-0.81.30.90.90.9-1.0
Cocaine response after cond. corrected0.10.20.4-0.5-0.6-0.40.6-0.1-0.0-0.1-0.1-0.2-0.10.3-0.30.3-0.30.5-0.10.60.6-0.7
Cocaine response after cond. not corrected1.21.32.9-0.5-0.60.20.7-0.8-1.1-1.1-1.1-1.2-1.21.3-1.11.1-1.21.61.01.51.7-1.7
Cocaine response before conditioning2.53.15.10.10.31.5-0.2-1.5-2.2-1.9-1.9-2.0-2.12.2-1.41.4-1.72.12.31.92.1-1.9
Saline control response2.33.07.12.42.41.2-2.5-0.30.10.50.50.70.7-0.52.7-2.72.3-1.5-1.7-2.2-1.71.8
Bone: connectivity density5.07.917.03.73.74.1-3.6-4.1-3.3-3.4-3.4-3.2-3.13.01.5-1.41.32.1-0.30.90.8-1.0
Bone: cortical apparent density0.20.30.9-0.9-0.9-0.70.90.40.20.10.20.10.1-0.1-0.70.7-0.70.20.40.50.4-0.3
Bone: cortical area2.23.46.41.61.62.3-1.5-2.5-2.4-2.4-2.4-2.4-2.32.3-0.10.1-0.22.00.71.41.4-1.5
Bone: cortical porosity0.20.20.50.20.2-0.1-0.10.40.00.60.60.60.5-0.20.5-0.60.3-0.5-0.3-0.7-0.10.1
Bone: cortical porosity0.20.20.5-0.3-0.3-0.40.30.70.10.60.70.60.5-0.20.0-0.1-0.2-0.40.3-0.40.2-0.3
Bone: cortical thickness1.72.75.81.51.62.1-1.4-2.4-2.0-2.3-2.3-2.2-2.12.00.00.00.01.80.41.21.0-1.0
Bone: cortical thickness0.60.72.21.41.51.3-1.4-1.0-0.7-0.7-0.7-0.6-0.50.51.0-0.90.80.1-0.5-0.2-0.30.4
Bone: cortical tissue density0.20.31.0-1.0-1.0-0.81.00.50.30.20.30.20.2-0.2-0.70.7-0.70.20.30.40.3-0.2
Condit. Reinf. active minus inactive responses0.60.61.4-1.2-1.1-0.61.10.4-0.0-0.00.0-0.1-0.10.2-1.21.2-1.20.61.00.90.9-0.8
Condit. Reinf. active-inactive response ratio0.60.61.3-0.8-0.8-0.20.8-0.0-0.6-0.4-0.3-0.5-0.50.8-1.01.0-1.20.71.11.11.1-1.0
Condit. Reinf. active responses0.40.51.3-0.9-0.8-0.30.80.2-0.2-0.1-0.1-0.2-0.20.3-1.01.0-1.10.61.10.80.8-0.7
Condit. Reinf. inactive responses0.20.20.5-0.7-0.7-0.40.60.60.20.30.30.30.2-0.1-0.60.6-0.70.10.70.10.3-0.3
Incentive salience index mean0.70.82.1-1.0-0.9-0.20.90.1-0.3-0.4-0.3-0.5-0.50.5-1.41.4-1.40.91.41.21.0-1.0
Condit. Reinf. lever presses0.81.12.5-0.6-0.50.30.5-0.4-0.8-0.8-0.8-0.9-1.00.9-1.31.3-1.41.21.61.41.2-1.2
Condit. Reinf. active minus inactive responses0.50.61.81.21.31.2-1.3-1.1-0.4-0.8-0.8-0.7-0.70.50.7-0.60.60.3-0.3-0.2-0.50.5
Condit. Reinf. active-inactive response ratio0.20.20.70.50.60.2-0.6-0.10.40.10.10.20.2-0.30.6-0.50.6-0.4-0.5-0.6-0.80.7
Condit. Reinf. active responses1.11.53.31.21.41.8-1.3-1.8-1.4-1.7-1.7-1.6-1.61.40.1-0.0-0.11.20.60.70.5-0.4
Condit. Reinf. inactive responses0.91.12.10.70.81.4-0.8-1.3-1.5-1.4-1.4-1.3-1.41.3-0.20.3-0.51.10.90.90.9-0.8
Condit. Reinf. lever presses1.52.13.60.50.71.5-0.6-1.6-1.8-1.8-1.8-1.8-1.91.9-0.90.9-1.01.71.51.61.4-1.4
Condit. Reinf. lever reinforcers received0.71.02.10.91.11.4-1.0-1.4-1.1-1.3-1.3-1.3-1.31.1-0.00.1-0.20.90.60.60.4-0.3
Conditioned reinforcement - actives2.92.98.02.82.82.3-2.6-1.9-0.9-1.1-1.1-0.9-0.90.52.0-2.02.10.0-1.5-1.0-1.31.1
Conditioned reinforcement - inactives0.80.92.01.00.90.2-0.9-0.00.60.40.40.50.5-0.81.2-1.21.4-0.7-1.3-1.1-1.41.4
Conditioned locomotion2.02.46.12.32.52.4-2.3-2.2-1.5-1.7-1.7-1.5-1.51.31.2-1.11.10.8-0.3-0.0-0.30.2
Patch foraging indifference point 0 sec0.10.10.20.40.40.4-0.3-0.4-0.1-0.5-0.5-0.3-0.30.20.2-0.10.2-0.0-0.1-0.2-0.20.4
Patch foraging indifference point AUC0.50.61.71.21.31.0-1.2-0.8-0.1-0.6-0.6-0.5-0.5-0.10.8-0.80.9-0.0-0.6-0.6-0.80.7
Delay disc. indifference point, 0s delay0.30.41.1-0.5-0.5-0.20.6-0.3-0.5-0.4-0.4-0.6-0.50.6-0.70.7-0.50.80.21.11.0-1.0
Delay disc. indifference point, 16s delay0.20.20.8-0.7-0.8-0.30.6-0.00.2-0.1-0.2-0.2-0.3-0.0-0.90.9-0.60.50.40.60.4-0.4
Delay disc. indifference point, 2s delay3.03.47.2-2.1-2.0-0.82.00.3-0.8-0.5-0.4-0.8-0.91.2-2.62.6-2.71.52.42.42.5-2.5
Delay disc. indifference point, 24s delay0.40.41.0-0.9-0.9-0.80.80.61.00.50.50.40.4-0.7-0.60.6-0.3-0.20.00.1-0.30.3
Delay disc. indifference point, 4s delay1.71.83.8-1.5-1.5-0.51.40.1-0.5-0.6-0.5-0.7-0.80.9-2.02.0-1.91.21.71.81.7-1.7
Delay disc. indifference point, 8s delay0.40.41.0-0.8-0.9-0.40.70.3-0.20.00.1-0.1-0.20.1-1.01.0-0.90.40.90.50.9-0.9
Indifference point function ln k0.50.61.50.50.4-0.1-0.50.70.21.01.01.01.0-0.41.1-1.10.7-1.2-0.5-1.1-0.60.7
Indifference point function log k0.50.61.50.50.4-0.1-0.50.70.21.01.01.01.0-0.41.1-1.10.7-1.2-0.5-1.1-0.60.7
Patch foraging total patch changes 0 sec0.10.10.30.40.50.4-0.4-0.4-0.0-0.4-0.4-0.3-0.20.10.2-0.20.3-0.1-0.1-0.4-0.30.5
Patch foraging total patch changes 12 sec0.20.20.50.50.50.6-0.3-0.6-0.5-0.7-0.7-0.6-0.60.40.1-0.10.10.30.1-0.10.2-0.1
Patch foraging total patch changes 18 sec0.30.41.20.50.70.1-0.6-0.00.50.10.10.20.2-0.60.6-0.60.7-0.6-0.7-0.9-1.01.1
Patch foraging total patch changes 24 sec0.10.10.30.30.50.6-0.3-0.4-0.1-0.5-0.5-0.5-0.50.2-0.30.3-0.20.30.5-0.1-0.30.3
Patch foraging total patch changes 6 sec0.20.30.80.80.90.9-0.7-0.8-0.5-0.7-0.7-0.6-0.60.40.3-0.30.30.3-0.0-0.2-0.10.2
Patch foraging time to switch 0 sec1.62.47.3-2.5-2.7-2.02.71.30.60.60.60.40.4-0.1-2.02.0-1.70.60.91.41.5-1.4
Patch foraging water rate 0 sec2.13.410.23.13.22.5-3.1-1.7-1.0-0.8-0.8-0.6-0.60.52.4-2.42.1-0.5-1.1-1.4-1.31.3
Patch foraging water rate 12 sec0.20.41.21.01.10.9-1.1-0.4-0.4-0.1-0.1-0.1-0.10.20.8-0.80.5-0.2-0.0-0.6-0.50.4
Patch foraging water rate 18 sec0.00.10.40.00.20.1-0.10.3-0.20.30.40.30.20.00.1-0.1-0.3-0.30.6-0.2-0.0-0.0
Patch foraging water rate 24 sec1.11.54.42.12.11.7-2.0-0.9-0.9-0.3-0.2-0.2-0.30.61.8-1.71.3-0.5-0.5-1.1-0.50.4
Patch foraging water rate 6 sec0.60.92.11.01.11.5-1.1-1.2-1.4-1.0-1.0-1.0-1.11.30.1-0.1-0.21.00.80.50.6-0.6
Seeking ratio, delayed vs. immediate footshock3.13.68.2-1.5-1.5-2.41.42.42.92.22.22.32.3-2.80.1-0.20.5-1.7-1.1-1.5-1.72.0
Distance traveled before self-admin0.40.41.1-1.0-0.8-0.61.10.70.30.00.00.10.1-0.1-1.01.0-1.0-0.00.90.30.5-0.5
Distance traveled after self-admin0.10.10.50.20.20.5-0.3-0.5-0.3-0.6-0.7-0.5-0.60.2-0.30.4-0.10.40.30.3-0.1-0.0
Extensor digitorum longus weight3.814.932.24.74.85.7-4.7-5.6-4.7-4.8-4.8-4.6-4.54.41.4-1.31.03.40.51.81.7-1.4
Bone: elastic displacement0.30.41.01.01.00.7-0.9-0.5-0.5-0.2-0.2-0.2-0.10.20.9-0.90.80.0-0.6-0.4-0.20.3
Bone: elastic work2.53.27.52.72.72.7-2.6-2.4-2.1-1.8-1.7-1.7-1.61.61.5-1.51.31.1-0.60.10.3-0.3
Bone: endosteal estimation0.61.33.81.92.01.4-1.8-1.0-0.6-0.4-0.4-0.3-0.30.31.6-1.61.5-0.4-1.0-0.8-0.70.7
Bone: endosteal perimeter1.02.04.71.81.92.2-1.8-1.9-2.0-1.6-1.6-1.6-1.61.60.6-0.60.31.10.40.60.7-0.8
Epididymis fat weight1.43.25.70.10.01.4-0.0-1.7-1.9-2.2-2.1-2.3-2.32.1-1.51.5-1.62.42.02.11.9-1.7
Delta time in closed arm before/after self-admin0.10.10.60.50.60.3-0.50.1-0.0-0.0-0.00.10.1-0.10.5-0.50.4-0.2-0.1-0.3-0.50.8
Delta time in open arm before/after self-admin2.01.95.0-2.2-2.2-1.62.21.10.60.70.70.50.5-0.2-1.81.8-1.80.21.30.91.2-1.4
Diff in mean of infusions in LGA sessions0.40.51.00.20.20.8-0.2-0.7-0.9-0.9-0.9-0.8-0.90.8-0.40.4-0.70.61.00.40.8-0.9
Delay discount exponential model param1.21.22.81.31.40.5-1.2-0.20.30.30.20.50.5-0.51.7-1.71.6-0.9-1.4-1.3-1.41.4
Extinction: sum of active levers before priming1.21.23.0-1.3-1.3-0.51.40.1-0.1-0.5-0.4-0.5-0.60.3-1.71.7-1.61.11.41.61.1-1.1
Active lever presses in extinction session 60.80.81.80.50.50.9-0.7-1.2-0.9-1.3-1.3-1.2-1.21.1-0.40.4-0.31.10.50.80.7-0.7
Bone: final force1.32.15.72.32.42.0-2.3-1.8-1.2-1.2-1.2-1.0-1.00.91.6-1.61.50.3-1.1-0.4-0.30.1
Bone: final moment1.01.74.82.22.21.7-2.1-1.5-0.9-0.9-0.9-0.7-0.70.71.6-1.61.50.1-1.1-0.6-0.50.3
Food consumed during 24 hour testing period0.91.12.00.70.6-0.1-0.70.50.80.90.91.01.0-0.91.4-1.41.2-1.3-1.1-1.3-1.31.3
Glucose0.20.31.1-1.0-1.0-0.91.10.50.40.30.30.20.3-0.3-0.70.6-0.5-0.00.10.40.2-0.2
Heart weight1.11.54.20.90.80.2-0.70.61.30.80.81.00.9-1.31.3-1.21.4-1.4-1.1-1.9-2.02.1
Delay discount hyperbolic model param1.21.33.01.41.50.6-1.3-0.30.20.20.10.40.5-0.51.7-1.71.6-0.9-1.4-1.3-1.51.5
Intermittent access intake day 1-15 change1.31.32.91.71.61.0-1.6-0.60.0-0.00.0-0.0-0.0-0.31.5-1.51.7-0.6-1.5-1.2-1.31.2
Intermittent access intake escalation1.11.12.91.71.61.2-1.7-0.9-0.4-0.3-0.3-0.3-0.40.11.3-1.31.4-0.3-1.1-0.9-0.90.8
Intermittent access intake escalation 20.20.20.40.60.50.4-0.6-0.10.10.00.10.0-0.0-0.20.5-0.50.6-0.4-0.5-0.6-0.50.4
Intermitt. access day 1 inactive lever presses1.11.23.90.90.80.1-0.90.11.00.60.60.70.7-1.21.3-1.31.4-0.9-1.3-1.4-1.72.0
Intermitt. access day 15 inactive lever presses0.20.20.5-0.5-0.6-0.70.70.60.00.70.70.50.6-0.2-0.00.00.0-0.2-0.40.00.4-0.3
Intermitt. access escalation Index0.10.10.5-0.2-0.30.10.20.1-0.3-0.0-0.0-0.0-0.20.0-0.40.4-0.50.10.70.10.0-0.2
Intermittent access day 1 total infusions0.40.51.3-1.0-0.9-0.50.90.40.10.10.10.0-0.10.2-1.11.1-1.00.31.00.80.5-0.7
Intermittent access day 15 total infusions0.10.10.30.50.50.6-0.5-0.3-0.4-0.2-0.1-0.3-0.40.40.1-0.10.20.10.0-0.0-0.2-0.1
Intermittent access terminal intake (last 3 days)0.00.10.2-0.3-0.3-0.20.30.20.00.20.20.0-0.00.1-0.40.4-0.20.10.20.30.0-0.2
Intermittent access total infusions0.30.40.9-0.7-0.7-0.30.70.2-0.3-0.0-0.0-0.2-0.20.4-1.01.0-0.90.50.80.80.6-0.8
Intermittent access day 1 locomotion1.81.94.8-1.7-1.5-0.61.50.4-0.7-0.3-0.3-0.4-0.50.8-2.02.0-2.21.02.21.61.7-1.7
Intermittent access day 15 total locomotion0.50.61.30.30.40.9-0.5-0.7-1.0-0.8-0.8-0.9-0.91.0-0.50.6-0.70.61.20.60.5-0.8
Intermittent access total locomotion0.80.93.0-1.0-0.8-0.10.80.1-0.5-0.3-0.3-0.5-0.50.6-1.51.5-1.60.81.71.11.0-1.2
Intermittent access standard deviation0.20.20.90.60.50.2-0.5-0.00.00.20.20.10.2-0.10.7-0.70.8-0.4-0.9-0.6-0.30.4
Left kidney weight5.214.738.16.26.15.7-5.8-5.0-3.5-3.6-3.6-3.2-3.12.93.8-3.73.51.3-2.0-0.7-0.70.8
Right kidney weight4.011.329.25.45.34.9-4.9-4.4-3.1-3.1-3.1-2.8-2.62.53.4-3.43.11.2-1.9-0.8-0.60.8
Cocaine induced anxiety1.82.14.2-0.8-0.70.50.7-0.7-1.2-1.3-1.3-1.4-1.51.3-1.81.8-1.91.62.11.91.8-1.9
Post-drug Anxiety2.73.06.9-2.6-2.6-1.62.61.20.30.30.30.1-0.00.2-2.52.5-2.50.82.01.81.7-1.9
Baseline Anxiety2.42.66.8-2.6-2.6-2.52.62.01.51.51.51.41.4-1.1-1.51.5-1.2-0.50.40.40.3-0.4
Tail length4.212.930.95.65.55.3-5.3-5.0-3.8-3.5-3.5-3.3-3.03.23.3-3.22.91.7-1.50.1-0.20.1
Length with tail8.731.873.08.58.38.3-8.0-8.0-5.8-6.0-6.0-5.5-5.25.14.7-4.64.33.1-2.30.5-0.20.2
Length without tail6.313.730.54.74.45.3-4.3-5.5-4.4-4.7-4.8-4.5-4.34.01.6-1.61.53.1-0.31.51.2-1.1
Times rat made contact with spout1.01.23.31.31.20.5-1.30.10.10.60.60.70.7-0.41.8-1.81.4-1.3-1.1-1.6-0.91.0
Lifetime Intake0.40.41.0-1.0-0.9-0.61.00.3-0.10.10.1-0.0-0.00.3-1.01.0-0.90.40.60.80.6-0.8
Liver weight, left0.61.02.41.51.51.1-1.5-1.0-0.4-0.5-0.5-0.4-0.30.11.3-1.31.3-0.3-1.0-0.8-0.81.0
Liver weight, right2.74.410.13.03.03.2-3.0-3.0-2.4-2.5-2.4-2.3-2.22.01.3-1.31.11.4-0.20.30.2-0.4
Locomotor activity1.32.05.72.42.32.2-2.4-1.7-1.4-1.1-1.0-0.9-0.91.11.6-1.61.20.3-0.5-0.5-0.40.5
Locomotor testing distance0.71.13.31.71.71.2-1.8-0.8-0.7-0.1-0.1-0.1-0.10.41.6-1.61.2-0.3-0.8-0.9-0.60.8
Locomotor testing rearing0.10.20.50.10.1-0.1-0.20.5-0.20.70.70.60.50.10.5-0.60.1-0.50.0-0.60.10.0
Locomotion in novel chamber0.81.02.20.91.10.3-0.80.20.60.50.50.80.7-0.81.2-1.21.2-1.2-0.9-1.5-1.41.5
Locomotion in novel chamber post-restriction1.31.55.62.12.41.8-1.9-1.3-0.9-0.7-0.6-0.6-0.60.71.5-1.51.2-0.2-0.5-0.8-0.80.8
Fecal boli incidents, locomotor time 11.11.23.01.71.71.7-1.7-1.5-0.9-1.0-1.0-1.0-0.90.81.0-1.00.70.5-0.1-0.3-0.40.4
Change in fecal boli incidents, locomotor task0.70.61.8-1.0-1.1-1.41.01.10.81.01.01.01.0-0.7-0.20.2-0.1-0.6-0.5-0.30.0-0.0
Time >=10cm from walls, locomotor time 11.51.53.4-1.4-1.4-0.51.30.3-0.6-0.3-0.4-0.5-0.60.9-1.71.7-1.91.11.71.51.6-1.6
Bouts of movement, locomotor time 10.91.02.71.61.51.4-1.6-1.1-0.8-0.6-0.6-0.6-0.60.61.1-1.11.10.3-0.6-0.4-0.60.6
Total resting periods, locomotor time 10.80.92.41.51.41.4-1.5-1.1-0.8-0.6-0.7-0.7-0.60.71.0-1.00.90.6-0.5-0.2-0.50.5
Rest time, locomotor task time 10.70.81.81.21.11.4-1.1-1.2-1.2-1.0-1.0-1.1-0.91.10.5-0.50.31.00.10.40.3-0.3
Distance moved, locomotor task time 10.40.40.9-0.7-0.6-0.80.60.90.90.50.60.80.7-0.8-0.30.3-0.2-0.9-0.0-0.4-0.40.3
Vertical activity count, locomotor time 10.10.10.40.30.40.2-0.4-0.10.3-0.2-0.10.1-0.0-0.40.1-0.10.4-0.4-0.4-0.4-0.60.6
Time >=10cm from walls, locomotor time 22.12.24.90.20.21.1-0.2-1.4-2.2-1.7-1.7-1.8-1.81.8-0.90.9-1.21.91.41.51.9-1.9
Bouts of movement, locomotor time 21.31.43.31.41.31.8-1.3-1.7-1.6-1.4-1.4-1.5-1.51.30.3-0.20.11.10.50.50.7-0.6
Total resting periods, locomotor time 21.21.33.01.31.31.7-1.3-1.6-1.5-1.4-1.3-1.4-1.41.20.3-0.30.11.00.30.40.6-0.6
Rest time, locomotor task time 20.20.20.7-0.2-0.30.10.2-0.0-0.7-0.2-0.1-0.3-0.30.6-0.40.4-0.70.40.80.30.8-0.7
Distance moved, locomotor task time 21.21.42.60.40.3-0.6-0.40.81.31.01.01.21.2-1.41.2-1.21.4-1.4-1.6-1.3-1.61.6
Vertical activity count, locomotor time 21.92.04.92.02.01.1-1.9-0.80.2-0.2-0.20.10.1-0.61.9-1.82.2-0.8-2.0-1.4-1.81.8
Light reinforcement 10.40.82.3-1.5-1.3-0.91.30.60.30.10.20.0-0.0-0.2-1.51.5-1.30.41.00.70.5-0.6
Light reinforcement 20.50.71.4-0.5-0.4-1.00.40.91.11.11.11.01.1-1.20.2-0.20.5-0.8-0.7-0.8-0.90.9
Bone: marrow area0.61.43.91.92.01.4-1.9-0.9-0.6-0.3-0.4-0.2-0.20.21.7-1.71.5-0.5-1.1-0.9-0.80.8
Bone: maximum diameter1.22.34.61.81.92.1-1.7-2.1-2.0-1.8-1.9-1.8-1.71.80.6-0.50.41.40.10.80.8-0.8
Bone: maximum force1.42.56.22.42.52.3-2.4-2.1-1.6-1.6-1.6-1.4-1.41.51.3-1.31.20.7-0.60.00.1-0.2
Bone: maximum moment1.11.95.22.22.32.0-2.2-1.8-1.3-1.3-1.3-1.1-1.11.21.4-1.31.20.5-0.7-0.2-0.1-0.1
Mean time between licks in bursts0.70.92.3-1.5-1.4-1.41.51.40.91.01.00.90.8-0.7-0.90.9-0.8-0.40.5-0.00.2-0.4
Mean num. licks in bursts1.61.94.4-0.3-0.40.70.3-0.9-1.7-1.3-1.3-1.3-1.41.7-1.21.2-1.51.41.71.52.1-2.1
Cd content in liver1.82.04.2-0.8-0.7-1.40.61.82.11.81.81.81.7-1.90.3-0.30.3-1.8-0.5-1.5-1.51.4
Co content in liver1.51.73.10.70.7-0.3-0.70.81.11.31.31.31.4-1.31.6-1.71.5-1.6-1.5-1.8-1.71.5
Cu content in liver0.10.10.30.10.20.4-0.2-0.4-0.2-0.5-0.5-0.5-0.50.2-0.30.3-0.30.30.50.20.1-0.3
Fe content in liver4.65.59.51.61.72.9-1.8-3.0-3.0-3.1-3.1-3.0-3.02.9-0.60.7-0.92.51.71.92.0-2.1
K content in liver0.40.40.7-0.2-0.10.30.2-0.5-0.7-0.7-0.7-0.7-0.70.6-0.70.7-0.70.80.80.70.8-0.8
Mg content in liver0.10.10.30.50.50.4-0.5-0.4-0.1-0.2-0.2-0.2-0.10.00.4-0.30.40.0-0.3-0.2-0.20.2
Mn content in liver1.11.32.3-0.6-0.7-1.30.61.41.51.51.51.41.4-1.50.5-0.50.6-1.2-1.0-1.0-1.00.9
Na content in liver0.30.40.70.30.30.6-0.3-0.7-0.8-0.8-0.7-0.8-0.70.7-0.20.2-0.30.70.40.50.7-0.8
Rb content in liver1.62.05.0-2.1-1.8-1.11.90.60.1-0.2-0.1-0.3-0.40.3-2.22.2-2.11.01.81.41.2-1.4
Se content in liver5.56.710.50.10.22.0-0.2-2.6-2.9-3.2-3.1-3.2-3.23.1-2.02.1-2.23.22.63.13.1-3.0
Sr content in liver1.11.02.60.60.5-0.3-0.40.41.00.80.80.90.9-1.11.3-1.31.4-1.0-1.6-1.1-1.31.3
Zn content in liver1.41.54.02.01.91.6-1.9-1.6-0.6-1.0-1.0-0.8-0.70.41.4-1.41.50.1-1.2-0.4-0.70.6
Bone: minimum diameter0.10.10.20.00.2-0.2-0.00.40.10.50.50.40.4-0.30.4-0.40.2-0.4-0.3-0.3-0.10.1
Time in familiar zone, hab. session 10.40.30.7-0.5-0.7-0.90.60.80.50.80.90.80.8-0.50.2-0.20.1-0.6-0.4-0.3-0.10.2
Time in novel zone, hab. session 10.30.30.60.60.70.7-0.6-0.8-0.4-0.7-0.7-0.6-0.60.50.1-0.10.20.50.00.3-0.0-0.0
Total zone transitions, hab. session 10.50.82.1-1.4-1.3-0.91.30.80.70.20.30.20.1-0.4-1.41.4-1.10.41.00.50.2-0.2
Total locomotion distance, hab. session 11.31.94.8-1.3-1.2-0.21.3-0.3-0.4-1.0-1.0-1.1-1.10.8-2.22.2-1.81.71.71.81.2-1.2
Locomotion velocity, hab. session 11.42.05.9-1.8-1.7-0.71.80.2-0.0-0.6-0.6-0.7-0.80.4-2.42.4-2.11.31.91.71.1-1.2
Time in familiar zone, hab. session 20.10.10.3-0.3-0.4-0.10.4-0.1-0.2-0.3-0.3-0.3-0.30.3-0.40.4-0.40.50.30.50.4-0.4
Time in novel zone, hab. session 20.10.10.2-0.3-0.3-0.40.30.50.30.50.50.40.4-0.3-0.10.1-0.1-0.30.1-0.1-0.10.1
Total zone transitions, hab. session 20.50.71.30.50.4-0.1-0.50.40.80.70.70.70.7-0.90.9-0.91.1-0.9-1.1-1.1-1.11.0
Total locomotion distance, hab. session 20.10.10.2-0.3-0.4-0.40.30.40.40.30.20.30.2-0.4-0.20.2-0.0-0.1-0.0-0.1-0.20.1
Locomotion velocity, hab. session 20.10.10.4-0.3-0.4-0.40.30.40.60.40.30.40.4-0.6-0.10.10.1-0.3-0.2-0.4-0.40.4
Novel to familiar place preference ratio0.70.81.30.0-0.1-0.70.00.91.01.11.11.11.1-0.90.8-0.80.8-1.1-0.9-0.9-0.90.9
Novelty place preference0.90.91.7-0.3-0.4-0.90.41.21.21.31.31.31.3-1.10.6-0.60.6-1.2-0.8-0.9-0.80.9
Time in novel zone, NPP test0.60.61.2-0.1-0.2-0.70.20.90.91.11.11.11.1-0.90.7-0.70.6-1.0-0.7-0.8-0.70.8
Total zone transitions, NPP test0.00.00.10.30.30.3-0.3-0.1-0.1-0.1-0.1-0.1-0.1-0.00.1-0.10.10.20.0-0.1-0.10.0
Total locomotion distance, NPP test1.21.73.0-0.4-0.30.70.3-0.9-1.3-1.3-1.3-1.4-1.41.3-1.41.4-1.41.71.61.61.6-1.6
Locomotion velocity, NPP test0.81.11.9-0.1-0.00.8-0.0-0.9-1.1-1.2-1.2-1.2-1.21.1-1.11.1-1.01.41.31.21.2-1.2
Intraocular pressure1.72.45.01.71.82.2-1.7-2.1-1.8-1.9-2.0-1.9-1.92.00.3-0.30.11.40.51.01.0-1.1
Delta distance traveled before/after self-admin0.40.41.10.90.80.6-1.1-0.60.1-0.1-0.1-0.0-0.1-0.30.8-0.81.0-0.1-0.9-0.5-1.00.8
Delta ambulatory time before/after self-admin0.10.10.20.30.10.1-0.4-0.10.20.20.10.10.0-0.30.3-0.30.4-0.1-0.4-0.2-0.50.4
Parametrial fat weight0.30.62.00.30.2-0.40.00.20.80.60.60.60.8-0.90.8-0.81.1-0.7-1.4-0.8-0.91.0
Pavlov. Cond. lever latency1.31.64.42.12.01.4-2.0-1.1-0.5-0.4-0.5-0.3-0.20.31.9-1.91.8-0.4-1.4-1.1-0.80.8
Pavlov. Cond. magazine entry latency0.10.10.30.60.60.5-0.5-0.4-0.5-0.2-0.2-0.2-0.20.40.4-0.40.20.10.00.10.1-0.0
Pavlov. Cond. change in total contacts0.80.82.0-1.2-1.1-0.51.10.1-0.2-0.4-0.3-0.4-0.40.5-1.41.4-1.30.91.21.21.0-0.8
Pavlov. Cond. index score0.40.51.0-0.5-0.40.10.4-0.2-0.6-0.5-0.4-0.6-0.60.6-0.90.9-0.90.81.01.00.9-0.8
Pavlov. Cond. latency score0.50.61.4-0.8-0.7-0.10.7-0.0-0.5-0.4-0.3-0.5-0.50.5-1.11.1-1.20.91.21.11.0-0.9
Pavlov. Cond. lever contacts1.11.33.1-1.7-1.6-1.01.70.70.20.10.20.0-0.10.0-1.71.7-1.70.61.41.10.9-0.9
Pavlov. Cond. magazine entry number0.40.51.3-0.7-0.8-1.00.70.81.20.80.80.80.8-1.0-0.10.00.2-0.7-0.6-0.5-0.70.6
Pavlov. Cond. intertrial magazine entries0.70.92.0-0.9-1.0-1.20.91.41.21.31.31.31.2-1.1-0.10.1-0.1-1.0-0.1-0.6-0.60.5
Pavlov. Cond. lever-magazine prob. diff.0.40.40.9-0.5-0.40.10.5-0.2-0.6-0.5-0.4-0.5-0.50.6-0.80.8-0.90.81.01.00.9-0.9
Pavlov. Cond. response bias0.40.50.90.00.10.6-0.1-0.6-0.9-0.7-0.7-0.8-0.80.8-0.60.6-0.70.90.90.90.9-0.8
Pavlov. Cond. lever latency0.70.92.10.40.2-0.5-0.30.50.90.90.91.01.0-1.11.1-1.21.2-1.1-1.4-1.3-1.21.1
Pavlov. Cond. magazine entry latency1.51.74.0-1.7-1.5-0.71.60.4-0.3-0.3-0.3-0.5-0.50.6-2.02.0-1.91.21.81.51.4-1.5
Pavlov. Cond. change in total contacts0.20.20.7-0.2-0.10.30.1-0.2-0.3-0.4-0.4-0.5-0.50.5-0.70.7-0.60.60.80.50.5-0.6
Pavlov. Cond. index score0.91.12.8-1.0-0.8-0.10.9-0.0-0.5-0.5-0.5-0.7-0.80.7-1.61.6-1.61.11.71.31.2-1.2
Pavlov. Cond. latency score1.01.32.9-1.1-0.9-0.11.0-0.0-0.5-0.6-0.6-0.7-0.80.8-1.71.7-1.71.21.71.41.3-1.3
Pavlov. Cond. lever contacts1.62.14.0-0.6-0.50.60.5-0.8-1.4-1.3-1.3-1.4-1.51.6-1.71.7-1.81.72.01.91.8-1.8
Pavlov. Cond. magazine entry number0.91.12.91.61.40.8-1.5-0.6-0.1-0.0-0.00.10.2-0.11.7-1.71.6-0.7-1.4-0.9-0.91.0
Pavlov. Cond. intertrial magazine entries0.70.92.31.31.20.6-1.3-0.30.10.20.20.40.4-0.41.5-1.51.3-1.0-1.0-1.1-1.11.2
Pavlov. Cond. lever-magazine prob. diff.0.81.02.4-1.1-0.9-0.21.00.1-0.3-0.4-0.4-0.5-0.60.6-1.51.5-1.50.91.51.11.0-1.1
Pavlov. Cond. response bias1.92.65.7-1.1-0.90.30.9-0.6-1.2-1.3-1.3-1.4-1.51.5-2.22.2-2.21.92.42.11.9-1.9
Time in closed arm before self-admin0.91.02.51.61.51.1-1.6-1.0-0.1-0.5-0.5-0.3-0.2-0.11.3-1.31.5-0.3-1.2-0.8-0.90.7
Time in closed arm after self-admin1.21.23.21.71.81.1-1.6-0.60.1-0.3-0.3-0.0-0.1-0.31.5-1.41.4-0.6-0.9-1.2-1.41.4
Time in open arm before self-admin0.10.10.20.50.40.3-0.3-0.0-0.2-0.1-0.0-0.0-0.10.10.4-0.40.40.0-0.2-0.1-0.10.3
Time in open arm after self-admin0.40.51.5-0.8-0.9-0.50.80.2-0.50.00.0-0.1-0.10.5-0.80.7-0.90.40.70.71.2-1.2
Bone: periosteal estimation1.12.45.52.32.42.3-2.2-2.1-1.8-1.6-1.7-1.5-1.51.41.1-1.11.00.8-0.40.20.2-0.3
Bone: periosteal perimeter1.83.06.01.31.42.2-1.3-2.1-2.5-2.1-2.1-2.1-2.12.3-0.30.3-0.62.01.31.51.6-1.7
Bone: post-yield work0.91.32.40.60.71.3-0.7-1.4-1.2-1.5-1.6-1.5-1.51.4-0.50.6-0.61.21.01.10.9-1.0
Progressive ratio test 1 active lever presses0.30.30.80.80.80.5-0.7-0.50.0-0.1-0.1-0.1-0.1-0.10.7-0.60.9-0.3-0.8-0.5-0.80.6
Progressive ratio test 1 breakpoint0.40.41.00.80.80.4-0.7-0.40.1-0.0-0.0-0.00.0-0.20.7-0.71.0-0.4-1.0-0.5-0.90.8
Progressive ratio test 1 inactive lever presses1.31.43.41.51.40.7-1.4-0.30.50.30.30.30.4-0.71.6-1.61.6-0.9-1.3-1.4-1.71.8
Progressive ratio test 2 active lever presses0.70.82.11.51.51.3-1.4-1.0-0.5-0.7-0.6-0.6-0.70.40.8-0.71.0-0.0-0.6-0.5-0.80.4
Progressive ratio test 2 breakpoint0.40.41.21.01.10.8-1.0-0.50.0-0.2-0.2-0.2-0.20.00.7-0.60.9-0.3-0.6-0.6-1.00.6
Progressive ratio test 2 inactive lever presses2.02.46.72.62.51.9-2.5-1.1-0.7-0.3-0.2-0.3-0.30.42.1-2.12.0-0.6-1.2-1.3-1.41.3
Incentive Sensitization - Responses0.00.00.10.10.20.3-0.20.00.0-0.1-0.1-0.1-0.20.0-0.20.2-0.0-0.10.2-0.1-0.20.0
Incentive Sensitization - Breakpoint0.00.00.10.20.20.3-0.3-0.0-0.0-0.1-0.1-0.1-0.30.1-0.20.2-0.1-0.10.3-0.1-0.20.0
Sum of active levers in priming session hrs 5-62.52.45.5-1.2-1.2-0.01.1-1.0-1.0-1.4-1.4-1.5-1.41.3-2.12.1-1.82.01.52.41.8-1.7
Progressive ratio1.01.22.7-0.9-0.9-1.41.21.61.21.51.51.51.4-1.20.1-0.10.1-1.2-0.5-0.9-0.70.7
Food seeking constrained by brief footshock0.50.61.3-0.8-0.7-1.10.71.11.11.01.11.11.0-0.9-0.10.1-0.1-1.0-0.2-0.5-0.50.3
Seeking ratio, punishment vs. effort0.50.71.80.91.01.2-1.2-1.3-0.8-1.1-1.0-1.0-1.00.80.2-0.20.20.60.10.40.2-0.3
Retroperitoneal fat weight2.16.913.4-2.6-2.5-0.62.6-0.4-1.8-1.6-1.6-1.8-1.82.0-3.73.7-3.62.83.23.53.4-3.1
Reaction time number correct0.50.72.11.31.40.9-1.5-0.60.0-0.3-0.3-0.1-0.1-0.11.1-1.11.1-0.3-0.8-0.9-1.00.9
Reaction time mean minus median1.82.44.80.00.11.2-0.1-1.2-2.2-1.5-1.5-1.6-1.72.0-1.11.1-1.61.72.11.72.1-2.1
Reaction time mean minus median AUC0.40.52.1-0.5-0.50.20.40.0-0.8-0.2-0.2-0.3-0.50.6-0.80.8-1.20.61.40.71.0-1.0
Reaction time num false alarms0.20.31.3-0.3-0.20.20.10.0-0.7-0.3-0.3-0.4-0.40.6-0.60.6-0.90.41.10.60.7-0.8
Reaction time num false alarms AUC0.60.82.2-0.10.10.6-0.1-0.5-1.2-0.8-0.8-0.9-0.91.1-0.80.8-1.10.91.51.01.0-1.1
Reaction time trials correct on left0.50.72.11.31.40.9-1.5-0.60.0-0.3-0.3-0.1-0.1-0.11.1-1.11.1-0.3-0.8-0.9-1.00.9
Reaction time trials on left0.50.72.01.31.30.9-1.4-0.60.0-0.3-0.2-0.1-0.1-0.11.1-1.11.1-0.3-0.8-0.9-1.00.8
Reaction time mean1.52.15.8-2.3-2.4-1.92.31.60.60.91.00.80.7-0.3-1.71.7-1.7-0.21.20.81.2-1.3
Reaction time mean AUC1.62.15.7-2.3-2.4-1.72.31.50.40.80.80.60.5-0.2-1.81.8-1.8-0.01.40.91.3-1.4
Median of all reaction times2.43.39.1-2.9-3.0-2.72.92.31.41.61.61.41.3-1.0-1.91.9-1.7-0.70.90.50.9-1.1
Reaction time omissions0.60.81.8-1.3-1.3-0.81.31.0-0.30.50.50.40.20.1-1.01.0-1.4-0.11.30.31.1-1.3
Reaction time false alarm rate0.81.13.0-0.6-0.50.30.5-0.3-1.2-0.7-0.7-0.9-0.91.2-1.21.2-1.51.01.71.31.5-1.4
Reaction time premature initiation rate0.00.00.1-0.1-0.20.10.2-0.2-0.2-0.2-0.1-0.2-0.20.0-0.30.3-0.30.20.30.30.3-0.3
Reaction time premature initiations0.00.10.20.40.30.4-0.4-0.4-0.2-0.3-0.2-0.2-0.2-0.10.2-0.20.20.00.0-0.1-0.10.1
Std. dev. reaction times0.91.33.2-1.0-1.0-0.21.00.0-1.0-0.4-0.4-0.5-0.61.0-1.31.3-1.70.91.71.31.8-1.8
Reaction time trials completed0.50.72.01.31.30.9-1.4-0.60.0-0.3-0.2-0.1-0.1-0.11.1-1.11.1-0.3-0.8-0.9-1.00.8
Reaction time trials AUC0.30.51.51.11.10.8-1.2-0.5-0.0-0.3-0.3-0.1-0.1-0.10.8-0.80.8-0.2-0.5-0.7-0.80.6
Run reversals in cocaine runway, females0.20.20.6-0.6-0.6-0.20.60.0-0.1-0.2-0.1-0.3-0.20.1-0.80.8-0.60.60.50.80.4-0.5
Run reversals in cocaine runway, males1.11.02.30.40.4-0.3-0.50.90.91.11.11.11.1-1.21.1-1.10.9-1.4-0.8-1.5-1.31.3
Latency to leave start box in cocaine runway0.10.10.3-0.4-0.5-0.60.40.40.30.50.40.30.4-0.3-0.10.10.1-0.1-0.40.1-0.0-0.0
Latency to leave start box in cocaine runway, F0.10.21.10.30.1-0.1-0.2-0.20.30.10.20.10.2-0.20.5-0.40.8-0.1-1.1-0.0-0.40.4
Latency to leave start box in cocaine runway, M0.30.20.9-0.6-0.6-0.30.50.4-0.10.20.10.10.00.0-0.70.7-0.80.11.00.30.4-0.6
Std. dev. time between licks in bursts0.20.30.70.60.70.9-0.7-0.6-0.7-0.5-0.5-0.5-0.60.70.1-0.1-0.00.40.40.10.3-0.4
Total sessions with >9 infusions0.10.10.30.00.10.20.1-0.3-0.6-0.3-0.3-0.3-0.30.4-0.20.2-0.20.30.20.30.3-0.5
Short access day 1 total inactive lever presses0.80.91.90.30.1-0.5-0.10.90.71.21.31.21.1-0.91.0-1.10.9-1.2-1.0-1.4-1.01.2
Short access day 10 total inactive lever presses1.11.23.21.81.71.2-1.6-0.8-0.6-0.2-0.2-0.2-0.10.11.7-1.71.5-0.4-1.2-1.1-0.71.0
Short access day 1 total infusions0.91.03.1-1.6-1.6-1.51.81.10.70.80.90.70.7-0.6-1.01.0-0.8-0.20.20.30.3-0.5
Short access day 10 total infusions0.70.71.8-1.3-1.2-0.71.10.30.0-0.0-0.0-0.1-0.10.2-1.41.4-1.20.60.91.10.8-1.0
Short access total infusions0.60.62.1-1.3-1.3-1.21.50.70.40.40.50.30.4-0.2-1.01.0-0.70.10.10.60.5-0.6
Short access day 1 locomotion0.60.72.0-1.4-1.3-1.11.31.00.50.60.60.60.5-0.5-1.01.0-1.0-0.10.80.20.2-0.3
Short access day 10 total locomotion0.30.40.9-0.9-0.9-0.70.70.7-0.00.40.40.40.4-0.2-0.60.6-0.9-0.20.80.10.8-0.6
Short access total locomotion1.01.02.6-1.6-1.5-1.01.50.7-0.10.20.20.10.1-0.0-1.41.4-1.50.41.20.91.1-0.9
One hour access (0.3 mA shock)1.11.33.20.80.90.1-0.90.60.91.01.01.00.9-1.01.3-1.31.2-1.4-0.9-1.7-1.81.5
Compulsive drug intake2.62.65.0-2.0-1.9-2.21.82.22.21.91.91.81.8-2.0-0.70.7-0.5-1.3-0.0-0.9-0.91.0
One hour access (shock baseline)1.01.23.51.81.91.7-1.8-1.3-1.1-0.9-0.9-0.8-0.90.91.0-1.00.80.2-0.1-0.3-0.40.2
Social response proportion2.12.35.82.42.32.1-2.2-2.0-0.8-1.5-1.5-1.2-1.00.61.6-1.51.70.4-1.2-0.5-1.11.0
Social responses1.52.04.72.02.12.2-1.9-2.0-1.6-1.7-1.6-1.5-1.41.40.8-0.80.71.0-0.00.20.00.1
Social time1.41.83.8-1.8-1.8-2.01.91.91.71.61.61.51.5-1.4-0.70.7-0.6-0.70.2-0.3-0.50.6
Soleus weight1.64.89.92.32.53.1-2.3-3.1-2.6-2.9-2.9-2.7-2.72.60.3-0.20.12.20.71.31.3-1.1
Bone: stiffness0.50.82.01.21.31.4-1.3-1.2-1.0-1.1-1.1-1.0-1.01.00.4-0.40.30.50.10.10.3-0.4
Tibialis anterior weight4.816.334.34.84.95.8-4.8-5.9-5.1-5.0-5.1-4.8-4.74.71.4-1.31.03.50.52.02.0-1.7
Time to tail flick, vehicle, before self-admin0.50.51.5-1.2-1.2-0.91.20.60.7-0.1-0.00.00.1-0.5-1.11.1-0.80.00.40.40.3-0.3
Time to tail flick, vehicle, after self-admin0.10.20.4-0.6-0.6-0.40.60.30.20.10.10.10.1-0.4-0.60.6-0.50.30.40.4-0.00.1
Time to tail flick, test, before self-admin0.40.41.21.10.90.8-1.0-0.6-0.4-0.3-0.4-0.4-0.30.30.9-0.90.90.2-0.8-0.0-0.40.5
Time to tail flick, test, after self-admin0.60.71.8-0.3-0.30.20.2-0.8-0.5-1.0-1.0-1.1-1.00.7-1.01.1-0.61.20.41.30.7-0.7
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.4-0.3-0.30.30.30.00.40.40.30.2-0.1-0.20.2-0.30.20.40.3-0.1-0.0
Delta time to tail flick, test, before/after SA0.80.71.7-0.9-0.8-0.30.8-0.3-0.4-0.6-0.6-0.6-0.50.5-1.31.3-1.20.71.01.01.0-1.1
Tibia length1.95.414.03.73.62.5-3.5-2.3-0.8-1.1-1.0-0.8-0.60.33.3-3.23.3-0.4-2.9-1.4-1.71.6
Ambulatory time before self-admin1.01.02.8-0.7-0.30.20.7-0.2-1.0-0.9-0.8-0.8-0.80.9-1.41.4-1.50.91.71.01.3-1.3
Ambulatory time after self-admin0.60.71.1-0.0-0.00.6-0.0-0.7-0.9-1.0-1.0-1.0-1.00.9-0.80.8-0.81.01.00.80.7-1.0
Bone: tissue strength0.30.30.60.20.1-0.3-0.10.40.60.50.50.60.6-0.50.6-0.60.7-0.6-0.8-0.6-0.60.6
Total heroin consumption2.42.87.2-2.3-2.0-0.91.90.5-0.2-0.2-0.2-0.5-0.60.6-2.62.6-2.71.22.61.81.8-1.7
Bone: trabecular number3.55.511.82.82.83.3-2.6-3.4-3.0-3.0-3.0-2.8-2.72.80.9-0.80.72.10.01.11.1-1.2
Bone: trabecular spacing2.63.47.2-2.5-2.5-2.72.52.72.12.12.22.01.9-1.9-1.21.1-1.1-1.30.5-0.5-0.30.3
Bone: trabecular thickness6.07.114.22.52.63.6-2.4-3.8-3.5-3.5-3.5-3.4-3.33.30.2-0.1-0.02.70.91.91.9-1.9
Bone: trabecular tissue density0.71.01.9-0.3-0.20.50.3-0.7-1.0-1.0-1.0-1.1-1.11.1-1.11.1-1.21.31.41.31.3-1.1
Water consumed over 24 hours2.53.07.62.32.21.1-2.3-0.40.10.50.50.70.7-0.62.8-2.82.4-1.5-2.0-2.2-1.81.8
Number of responses in last shaping day0.20.20.50.30.4-0.1-0.20.30.10.60.60.50.5-0.30.6-0.60.4-0.6-0.4-0.7-0.40.4