Hub : Genes

Cers4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Cers4 0.04 0.03 8.6e-03 -0 0 -0 -0 4.3e-01 2.6e-01 6.8e-01 5.1e-01
2 RMTg gene expression Cers4 0.25 0.13 6.8e-04 0.08 0.11 0.04 0.09 3.1e-03 8.6e-04 3.0e-02 2.9e-03
3 BLA mRNA stability Cers4 0.15 0.09 3.5e-04 0.04 0.06 0.05 0.06 3.3e-03 4.9e-04 1.1e-03 6.7e-04
4 LHb gene expression Cers4 0.3 0.14 7.3e-04 0.06 0.08 0.14 0.12 2.0e-02 5.3e-03 3.5e-04 7.3e-04
5 NAcc gene expression Cers4 0.39 0.12 0.0e+00 0.38 0.42 0.43 0.43 8.7e-62 8.1e-70 8.0e-71 7.4e-71
6 pVTA gene expression Cers4 0.39 0.1 0.0e+00 0.32 0.43 0.43 0.44 3.5e-26 7.6e-38 1.6e-37 3.8e-38
7 Adipose mRNA stability Cers4 0.13 0.07 2.9e-12 0.08 0.08 0.08 0.07 5.9e-09 7.6e-09 8.3e-09 1.3e-08
8 IL gene expression Cers4 0.36 0.16 2.3e-06 0.26 0.1 0.2 0.01 6.6e-07 2.6e-03 1.3e-05 1.4e-01
9 OFC gene expression Cers4 0.57 0.16 1.2e-12 0.36 0.25 0.35 0.27 1.5e-09 9.5e-07 2.8e-09 4.5e-07
10 PL gene expression Cers4 0.51 0.14 0.0e+00 0.46 0.49 0.49 0.49 5.3e-56 7.1e-61 3.5e-61 2.7e-60
11 Brain gene expression Cers4 0.52 0.14 0.0e+00 0.59 0.45 0.61 0.28 3.0e-68 2.5e-46 3.1e-72 1.5e-26
12 BLA gene expression Cers4 0.36 0.14 0.0e+00 0.31 0.31 0.3 0.32 8.0e-17 4.5e-17 1.2e-16 1.1e-17
13 IC gene expression Cers4 0.46 0.13 0.0e+00 0.43 0.47 0.45 0.46 1.8e-19 9.7e-22 1.0e-20 2.3e-21
14 Adipose gene expression Cers4 0.44 0.11 0.0e+00 0.34 0.34 0.34 0.34 3.0e-39 3.3e-39 1.9e-38 1.4e-39
15 NAcc mRNA stability Cers4 0.03 0.02 2.3e-04 0.02 0.03 0.03 0.03 1.2e-04 5.3e-05 2.2e-05 2.2e-05
16 Adipose alternative polyA XM_006248804.5 0.13 0.07 6.6e-09 0.05 0.06 0.03 0.05 4.3e-06 8.9e-07 1.4e-04 3.3e-06
17 NAcc alternative polyA XM_006248804.5 0.03 0.02 4.7e-04 0.01 0.02 0.01 0.01 2.6e-03 4.5e-04 2.9e-03 1.7e-03
18 Adipose alternative polyA NM_001107117.2 0.12 0.07 7.5e-09 0.05 0.06 0.03 0.05 4.1e-06 1.0e-06 1.6e-04 3.3e-06
19 Brain isoform ratio NM_001107117.2 0.03 0.03 8.0e-03 0 0.01 0 0 2.3e-01 6.4e-02 2.8e-01 2.7e-01
20 Brain isoform ratio XM_006248804.5 0.03 0.03 7.6e-03 0 0 0 0 2.5e-01 9.8e-02 3.5e-01 3.3e-01
21 Brain mRNA stability Cers4 0.04 0.03 1.9e-03 0.03 0.03 0.03 0.02 9.1e-04 9.5e-04 1.8e-03 3.7e-03
22 Adipose isoform ratio NM_001107117.2 0.14 0.07 1.0e-11 0.07 0.08 0.05 0.08 1.9e-08 6.2e-09 1.2e-06 7.4e-09
23 Adipose isoform ratio XM_006248804.5 0.14 0.07 6.4e-12 0.07 0.08 0.06 0.08 1.5e-08 4.5e-09 5.8e-07 5.7e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density3.76.314.23.32.82.73.33.83.53.33.23.23.13.13.13.02.9-0.20.00.1-0.20.3-0.6-0.7-1.21.2
Area under the delay curve0.80.92.5-0.9-1.2-1.1-0.7-0.2-0.30.20.30.30.40.40.40.50.6-1.61.51.3-1.41.3-1.3-1.0-1.21.2
BMI with tail1.96.614.52.92.21.82.43.83.33.53.53.43.43.33.33.33.2-0.90.70.7-0.81.2-1.4-0.9-1.81.8
BMI without tail2.57.617.44.03.63.13.64.24.03.63.63.43.33.23.23.13.00.5-0.7-0.50.5-0.1-0.1-0.0-0.70.8
Body weight7.633.278.38.88.17.17.68.58.47.27.16.96.76.56.56.16.01.6-1.9-1.81.6-1.10.50.2-1.01.1
Weight adjusted by age0.30.51.41.01.11.00.90.40.60.70.20.00.10.1-0.10.10.20.9-1.2-0.91.1-0.80.80.50.8-0.8
Bone surface3.97.016.03.63.12.93.34.03.83.43.43.43.33.23.23.13.1-0.0-0.10.0-0.10.3-0.5-0.5-1.21.2
Bone volume3.66.413.42.82.12.12.73.73.33.43.33.33.33.23.23.23.1-0.90.80.9-0.91.1-1.3-1.2-1.81.8
Breakpoint value in progressive ratio session0.91.11.80.70.30.70.71.11.11.31.31.11.31.31.31.31.3-0.80.80.9-0.80.8-0.8-1.3-1.11.1
Number of licking bursts4.06.511.10.21.20.4-0.4-1.5-1.3-2.4-2.3-2.3-2.5-2.5-2.5-2.6-2.73.2-3.2-3.33.2-3.23.23.33.3-3.3
Context. condit. distance diff. score5.56.711.92.92.22.63.13.43.43.33.43.43.33.23.33.13.1-0.80.80.9-0.90.9-1.1-1.8-1.81.8
Locomotion velocity, session 10.10.10.5-0.6-0.7-0.4-0.5-0.6-0.50.0-0.3-0.3-0.2-0.2-0.2-0.1-0.1-0.30.30.5-0.30.4-0.4-0.5-0.20.2
Locomotion distance, session 10.60.72.2-1.4-1.3-1.1-1.1-1.5-1.2-0.8-0.9-0.9-0.8-0.8-0.8-0.7-0.6-0.50.60.5-0.50.4-0.3-0.4-0.10.1
Locomotion velocity, session 20.50.51.1-0.6-0.4-0.6-0.8-1.0-0.9-1.0-0.9-0.9-0.9-0.9-0.9-0.9-0.90.4-0.4-0.50.4-0.50.50.60.6-0.7
Locomotion distance, session 20.91.24.6-1.2-0.9-0.6-0.9-2.1-1.4-1.3-1.4-1.4-1.4-1.4-1.4-1.4-1.30.4-0.2-0.20.3-0.50.70.10.7-0.7
Locomotion velocity, session 31.21.42.70.90.50.71.11.51.31.61.51.41.51.41.51.41.4-0.80.80.8-0.90.8-0.9-1.0-1.21.2
Locomotion distance, session 30.10.10.20.20.10.30.40.10.30.40.30.30.30.20.30.20.3-0.10.20.1-0.20.0-0.0-0.3-0.20.2
Stereotopy head waving bouts, day 31.01.23.31.81.81.71.81.31.41.20.90.90.80.80.70.70.81.0-1.0-0.91.0-0.80.70.30.4-0.4
Stereotopy head waving duration, day 30.00.00.1-0.2-0.2-0.4-0.3-0.3-0.2-0.0-0.1-0.1-0.1-0.1-0.10.0-0.1-0.10.00.1-0.10.2-0.20.2-0.00.0
Locomotion velocity, session 70.30.30.8-0.9-0.9-0.9-0.9-0.8-0.7-0.4-0.4-0.5-0.4-0.4-0.3-0.3-0.3-0.50.50.4-0.40.5-0.4-0.0-0.20.2
Locomotion distance, session 70.00.10.2-0.2-0.3-0.00.0-0.10.10.00.10.00.10.10.10.10.2-0.30.40.4-0.40.3-0.2-0.4-0.30.3
Stereotopy head waving bouts, day 70.10.10.3-0.5-0.5-0.3-0.3-0.3-0.5-0.1-0.3-0.2-0.3-0.2-0.3-0.2-0.2-0.20.30.3-0.30.2-0.1-0.3-0.10.1
Stereotopy head waving duration, day 70.30.41.2-1.0-1.0-0.8-0.9-0.8-1.1-0.5-0.8-0.7-0.8-0.7-0.8-0.7-0.7-0.20.20.3-0.20.2-0.1-0.10.1-0.1
Locomotion velocity, session 80.00.00.10.30.30.10.30.10.20.20.30.40.30.20.20.20.20.0-0.1-0.20.1-0.10.00.1-0.00.0
Locomotion distance, session 81.21.73.21.71.31.41.71.61.81.61.81.81.71.71.71.61.6-0.30.30.2-0.30.3-0.4-0.7-0.80.8
Degree of sensitization distance0.70.71.7-1.2-1.0-1.1-1.3-1.2-1.1-1.3-1.0-1.1-1.0-1.0-1.0-0.9-0.9-0.10.10.0-0.00.00.00.30.3-0.3
Degree of sensitization stereotypy0.20.20.6-0.6-0.8-0.6-0.5-0.0-0.40.0-0.10.0-0.00.00.00.00.0-0.70.80.7-0.70.6-0.6-0.6-0.60.5
Conditioned locomotion0.80.91.40.3-0.00.20.50.70.81.01.11.21.11.11.21.11.1-0.91.01.0-1.11.0-1.0-1.0-1.21.2
Cocaine response after cond. corrected0.10.21.0-0.3-0.3-1.0-0.8-0.2-0.20.00.10.10.10.00.20.20.1-0.50.10.1-0.10.6-0.60.7-0.10.1
Cocaine response after cond. not corrected0.91.02.40.0-0.4-0.6-0.20.70.61.11.11.11.11.01.21.31.1-1.31.01.1-1.01.5-1.5-0.4-1.21.2
Cocaine response before conditioning2.93.45.90.80.11.11.61.91.72.22.02.02.12.22.02.12.1-1.61.82.0-1.81.6-1.6-2.4-2.12.1
Saline control response2.43.28.02.02.52.82.20.80.90.0-0.2-0.2-0.4-0.4-0.5-0.6-0.62.8-2.5-2.12.4-2.62.61.12.0-2.0
Bone: connectivity density4.77.316.64.03.63.43.84.13.93.33.33.33.23.13.12.92.90.5-0.6-0.50.5-0.40.1-0.2-0.70.7
Bone: cortical apparent density0.20.31.0-0.7-0.8-1.0-0.9-0.6-0.6-0.5-0.2-0.2-0.2-0.3-0.2-0.1-0.2-0.70.40.4-0.40.6-0.60.1-0.30.2
Bone: cortical area1.92.86.12.01.61.62.02.52.32.22.22.22.22.12.12.12.0-0.30.40.4-0.50.5-0.7-0.9-1.11.1
Bone: cortical porosity0.30.30.7-0.00.20.30.1-0.2-0.4-0.3-0.6-0.6-0.6-0.6-0.6-0.6-0.70.8-0.8-0.50.8-0.70.70.10.8-0.8
Bone: cortical porosity0.20.20.4-0.4-0.30.1-0.0-0.5-0.6-0.2-0.6-0.6-0.6-0.6-0.6-0.5-0.50.3-0.30.10.3-0.20.3-0.60.4-0.4
Bone: cortical thickness1.32.25.01.91.61.41.72.22.01.72.02.02.01.91.91.81.7-0.20.30.1-0.30.3-0.4-0.4-0.90.9
Bone: cortical thickness0.70.82.51.41.41.51.51.61.31.00.90.90.90.80.80.80.60.6-0.5-0.40.4-0.50.4-0.20.1-0.0
Bone: cortical tissue density0.20.31.2-0.8-0.8-1.1-1.0-0.7-0.7-0.6-0.3-0.3-0.3-0.4-0.3-0.2-0.3-0.70.40.3-0.40.5-0.50.2-0.20.2
Condit. Reinf. active minus inactive responses0.50.61.3-0.9-1.1-0.9-0.9-0.2-0.5-0.00.0-0.00.10.00.10.20.2-1.11.01.1-1.01.1-1.1-0.8-0.80.8
Condit. Reinf. active-inactive response ratio0.50.51.3-0.5-0.8-0.6-0.50.3-0.10.40.40.30.40.40.40.60.5-1.10.91.1-0.91.1-1.1-0.8-0.90.9
Condit. Reinf. active responses0.30.41.7-0.6-0.9-0.3-0.4-0.1-0.20.30.10.00.10.10.20.20.3-0.90.91.1-0.90.8-0.8-1.3-0.80.8
Condit. Reinf. inactive responses0.20.21.3-0.6-0.7-0.0-0.2-0.6-0.30.1-0.4-0.4-0.4-0.3-0.3-0.4-0.2-0.30.50.5-0.50.2-0.1-1.2-0.20.2
Incentive salience index mean0.60.82.1-0.7-1.0-0.5-0.40.2-0.10.30.40.30.50.40.50.50.5-1.31.41.4-1.31.2-1.2-1.4-1.21.2
Condit. Reinf. lever presses0.81.13.0-0.3-0.7-0.10.10.50.40.70.70.70.80.80.80.90.8-1.31.51.5-1.51.2-1.2-1.7-1.41.4
Condit. Reinf. active minus inactive responses0.40.51.51.21.21.21.11.10.90.40.70.70.60.60.60.50.40.6-0.5-0.50.4-0.60.50.30.1-0.1
Condit. Reinf. active-inactive response ratio0.20.20.50.30.50.50.3-0.2-0.0-0.4-0.3-0.3-0.3-0.3-0.3-0.4-0.40.7-0.5-0.60.6-0.70.70.70.5-0.5
Condit. Reinf. active responses1.11.53.81.61.31.61.61.91.71.31.61.61.51.51.51.41.30.00.20.3-0.30.1-0.2-0.6-0.70.7
Condit. Reinf. inactive responses1.11.43.71.10.81.21.31.91.51.51.51.51.41.41.41.41.3-0.30.50.7-0.60.5-0.6-1.0-0.90.9
Condit. Reinf. lever presses1.52.13.60.90.30.81.21.91.41.71.71.71.71.71.71.71.7-1.11.21.3-1.31.2-1.2-1.6-1.51.6
Condit. Reinf. lever reinforcers received0.71.02.61.21.01.31.31.61.31.01.21.21.21.21.21.11.0-0.00.30.3-0.30.1-0.1-0.6-0.60.6
Conditioned reinforcement - actives1.52.57.12.72.72.42.22.02.21.41.61.61.41.51.41.11.11.4-1.1-1.31.0-1.21.10.70.4-0.3
Conditioned reinforcement - inactives0.60.92.00.60.90.70.3-0.1-0.1-0.6-0.5-0.6-0.6-0.6-0.6-0.8-0.81.4-1.3-1.41.3-1.41.41.21.3-1.3
Conditioned locomotion2.22.96.62.42.22.62.52.32.42.12.12.12.02.02.11.71.80.5-0.2-0.20.2-0.40.3-0.5-0.50.5
Patch foraging indifference point 0 sec0.00.10.30.40.30.40.30.50.40.30.40.20.30.40.30.20.30.20.1-0.0-0.1-0.10.1-0.0-0.10.1
Patch foraging indifference point AUC0.50.82.31.31.51.21.10.70.80.10.40.50.40.30.30.10.11.1-1.0-1.20.9-1.11.11.00.7-0.7
Delay disc. indifference point, 0s delay0.30.30.80.1-0.1-0.7-0.10.30.40.60.60.60.60.50.60.70.8-0.70.40.3-0.40.8-0.9-0.1-0.60.6
Delay disc. indifference point, 16s delay0.30.30.9-0.3-0.4-0.4-0.2-0.00.0-0.00.40.40.40.40.40.40.4-0.90.90.6-0.90.6-0.6-0.3-0.80.8
Delay disc. indifference point, 2s delay2.52.86.4-1.5-2.1-1.6-1.0-0.2-0.30.70.50.40.70.70.81.01.1-2.52.42.5-2.32.5-2.5-2.1-2.12.1
Delay disc. indifference point, 24s delay0.40.41.3-0.9-0.9-1.0-1.0-0.9-0.9-1.1-0.6-0.5-0.5-0.6-0.6-0.6-0.6-0.40.50.2-0.50.2-0.20.3-0.10.1
Delay disc. indifference point, 4s delay1.71.84.1-0.9-1.4-1.1-0.60.1-0.00.60.70.70.80.80.91.01.0-2.01.91.9-1.91.9-1.9-1.7-1.81.8
Delay disc. indifference point, 8s delay0.30.41.1-0.5-0.7-0.4-0.2-0.0-0.20.20.20.20.20.20.20.20.4-1.01.00.8-1.00.7-0.7-0.9-0.80.8
Indifference point function ln k0.30.61.3-0.10.20.70.4-0.4-0.30.0-0.8-0.8-1.0-0.8-1.0-0.8-0.71.1-1.1-0.61.1-0.91.0-0.11.0-1.0
Indifference point function log k0.30.61.3-0.10.20.70.4-0.4-0.30.0-0.8-0.8-1.0-0.8-1.0-0.8-0.71.1-1.1-0.61.1-0.91.0-0.11.0-1.0
Patch foraging total patch changes 0 sec0.00.10.30.40.40.50.40.60.40.20.40.20.30.30.30.20.20.30.1-0.1-0.0-0.20.2-0.1-0.10.1
Patch foraging total patch changes 12 sec0.20.30.70.80.70.50.80.80.70.60.60.50.70.60.60.60.60.1-0.1-0.10.1-0.0-0.00.2-0.10.1
Patch foraging total patch changes 18 sec0.20.31.10.40.60.40.20.20.1-0.4-0.2-0.1-0.2-0.3-0.2-0.3-0.40.8-0.6-0.80.7-0.80.71.10.6-0.6
Patch foraging total patch changes 24 sec0.10.20.90.50.40.80.90.40.60.30.50.40.50.40.50.30.40.10.40.2-0.4-0.10.2-0.5-0.40.4
Patch foraging total patch changes 6 sec0.20.31.00.90.80.91.01.00.80.60.70.60.60.60.60.50.50.4-0.1-0.20.1-0.30.20.1-0.10.1
Patch foraging time to switch 0 sec1.12.38.8-2.1-2.4-3.0-2.5-1.3-1.4-0.5-0.5-0.5-0.3-0.4-0.20.1-0.1-2.21.61.5-1.62.1-2.1-0.3-1.21.1
Patch foraging water rate 0 sec1.53.111.42.62.83.42.71.71.90.90.70.70.60.60.50.20.32.4-1.9-1.61.8-2.22.20.41.3-1.2
Patch foraging water rate 12 sec0.20.52.70.80.91.71.30.70.70.40.10.20.10.20.10.00.10.9-0.5-0.30.5-0.80.9-0.60.4-0.3
Patch foraging water rate 18 sec0.10.21.7-0.1-0.10.90.8-0.20.10.2-0.4-0.5-0.3-0.2-0.3-0.3-0.10.3-0.00.30.0-0.40.4-1.30.1-0.1
Patch foraging water rate 24 sec1.21.77.21.72.02.72.01.11.20.80.30.20.00.2-0.0-0.00.11.8-1.6-1.11.6-1.71.7-0.11.1-1.1
Patch foraging water rate 6 sec0.71.03.31.21.01.81.81.31.41.41.00.91.01.01.00.91.00.10.10.4-0.2-0.10.1-1.2-0.50.5
Seeking ratio, delayed vs. immediate footshock3.03.68.8-2.0-1.5-1.9-2.4-2.5-2.4-3.0-2.3-2.3-2.3-2.4-2.2-2.3-2.30.6-0.6-0.80.7-0.80.91.81.3-1.4
Distance traveled before self-admin0.40.51.6-1.1-1.2-0.8-0.5-0.2-0.6-0.2-0.2-0.4-0.1-0.1-0.1-0.00.1-1.01.01.1-1.01.0-0.9-1.0-0.70.7
Distance traveled after self-admin0.30.40.80.20.00.40.50.50.50.40.80.60.70.70.70.60.7-0.50.90.7-0.90.4-0.4-0.7-0.80.8
Extensor digitorum longus weight4.417.236.05.85.05.25.66.06.05.15.45.35.05.04.94.64.60.4-0.2-0.1-0.0-0.1-0.2-1.5-1.71.7
Bone: elastic displacement0.20.20.60.70.80.80.80.30.40.30.10.10.0-0.00.1-0.0-0.10.7-0.7-0.60.7-0.60.6-0.10.5-0.5
Bone: elastic work2.33.07.82.82.72.72.82.42.41.91.71.71.61.51.61.41.31.2-1.1-0.91.0-0.90.8-0.30.2-0.2
Bone: endosteal estimation0.61.43.51.71.91.91.71.01.10.60.40.30.20.30.10.10.11.8-1.5-1.31.4-1.51.40.61.0-1.0
Bone: endosteal perimeter1.02.15.21.91.72.22.32.22.12.01.61.61.51.61.51.51.50.5-0.20.10.1-0.20.1-0.8-0.40.5
Epididymis fat weight0.62.13.10.60.10.40.91.51.21.41.81.61.71.71.71.71.6-1.41.51.5-1.51.4-1.5-1.5-1.71.7
Delta time in closed arm before/after self-admin0.20.20.70.50.60.80.40.50.20.1-0.00.0-0.0-0.0-0.0-0.1-0.10.7-0.7-0.50.7-0.70.70.10.5-0.5
Delta time in open arm before/after self-admin1.91.85.4-2.1-2.3-2.0-1.6-1.5-1.2-0.6-0.7-0.8-0.5-0.5-0.5-0.2-0.1-1.81.61.7-1.51.7-1.6-1.1-1.11.0
Diff in mean of infusions in LGA sessions0.30.41.10.70.50.81.00.70.80.80.80.70.70.80.70.70.7-0.10.10.3-0.20.2-0.2-0.8-0.40.4
Delay discount exponential model param1.01.23.01.01.41.10.80.30.4-0.1-0.3-0.3-0.4-0.4-0.4-0.5-0.61.7-1.7-1.51.6-1.51.51.31.4-1.3
Extinction: sum of active levers before priming1.41.63.0-0.1-0.6-0.4-0.10.60.50.81.21.11.31.31.21.31.4-1.71.71.5-1.71.5-1.6-1.3-1.71.7
Active lever presses in extinction session 60.90.91.70.90.60.70.61.21.20.91.31.21.31.21.31.11.2-0.50.60.4-0.60.4-0.5-0.3-0.80.9
Bone: final force1.21.95.52.22.42.01.91.71.60.90.90.90.80.70.70.50.51.7-1.5-1.51.4-1.41.31.00.8-0.8
Bone: final moment1.01.54.51.92.11.81.71.31.30.60.60.60.50.40.40.30.31.7-1.5-1.51.4-1.41.31.01.0-0.9
Food consumed during 24 hour testing period0.91.32.50.20.60.5-0.1-0.5-0.5-0.8-1.0-1.0-1.1-1.1-1.1-1.1-1.11.4-1.6-1.31.6-1.51.51.31.6-1.6
Glucose0.71.13.6-1.7-1.8-1.9-1.4-1.3-1.2-0.7-0.6-0.6-0.4-0.5-0.4-0.3-0.3-1.31.21.0-1.21.2-1.2-0.4-0.80.7
Heart weight0.40.62.20.91.11.51.20.30.40.10.10.2-0.0-0.0-0.1-0.2-0.21.2-0.9-0.80.9-1.21.2-0.00.7-0.7
Delay discount hyperbolic model param1.11.23.11.01.41.10.70.20.3-0.2-0.3-0.3-0.4-0.4-0.4-0.6-0.71.7-1.7-1.51.6-1.51.51.31.4-1.4
Intermittent access intake day 1-15 change0.51.12.61.31.61.00.60.90.6-0.10.20.20.00.0-0.1-0.2-0.31.5-1.3-1.61.3-1.41.41.51.1-1.1
Intermittent access intake escalation0.51.02.81.21.50.90.50.80.5-0.20.10.1-0.1-0.1-0.2-0.3-0.41.6-1.4-1.71.3-1.51.41.61.1-1.1
Intermittent access intake escalation 20.30.41.10.10.4-0.2-0.5-0.2-0.3-0.8-0.4-0.4-0.5-0.5-0.6-0.6-0.70.7-0.6-0.90.6-0.70.71.10.7-0.7
Intermitt. access day 1 inactive lever presses0.20.71.50.30.60.20.0-0.3-0.2-0.7-0.6-0.7-0.7-0.7-0.7-0.8-0.81.2-1.0-1.21.1-1.21.21.21.1-1.1
Intermitt. access day 15 inactive lever presses0.10.21.0-0.5-0.6-1.0-0.8-0.3-0.30.6-0.2-0.1-0.2-0.1-0.30.10.0-0.50.10.2-0.10.6-0.70.1-0.10.1
Intermitt. access escalation Index0.10.21.1-0.2-0.30.30.20.20.10.50.20.30.20.30.20.20.1-0.30.50.7-0.50.4-0.3-1.1-0.50.5
Intermittent access day 1 total infusions0.10.21.0-0.6-0.7-0.1-0.1-0.5-0.4-0.1-0.3-0.3-0.3-0.2-0.3-0.2-0.1-0.30.60.6-0.60.3-0.2-1.0-0.30.3
Intermittent access day 15 total infusions0.10.10.30.40.50.60.50.30.20.20.10.1-0.00.1-0.1-0.1-0.10.5-0.2-0.30.2-0.50.5-0.20.2-0.2
Intermittent access terminal intake (last 3 days)0.00.00.00.00.10.0-0.10.1-0.1-0.0-0.0-0.0-0.1-0.0-0.1-0.1-0.20.20.0-0.20.0-0.20.2-0.00.1-0.1
Intermittent access total infusions0.10.20.6-0.2-0.3-0.1-0.10.2-0.00.40.30.30.20.30.20.30.3-0.50.60.5-0.60.5-0.4-0.8-0.50.5
Intermittent access day 1 locomotion0.70.94.1-0.6-1.0-0.10.20.0-0.10.80.30.30.40.60.50.60.7-1.31.31.5-1.31.2-1.1-2.0-1.21.2
Intermittent access day 15 total locomotion0.30.62.30.80.71.51.40.90.81.00.60.70.60.80.60.50.70.30.20.3-0.2-0.30.3-1.3-0.30.3
Intermittent access total locomotion0.50.62.7-0.1-0.40.40.40.50.30.80.50.50.60.70.70.60.8-0.81.01.1-1.00.7-0.7-1.6-0.90.9
Intermittent access standard deviation0.10.21.40.20.3-0.4-0.6-0.2-0.2-0.3-0.3-0.3-0.3-0.3-0.4-0.3-0.40.5-0.6-0.90.6-0.50.41.20.6-0.6
Left kidney weight4.822.559.17.77.46.66.96.76.85.25.35.24.94.74.74.34.32.4-2.6-2.62.4-2.21.71.10.2-0.1
Right kidney weight3.415.742.56.56.45.75.85.55.64.24.03.93.63.63.53.23.22.6-3.0-2.72.8-2.31.91.30.9-0.8
Cocaine induced anxiety1.21.73.00.1-0.4-0.10.30.91.00.81.41.41.51.41.51.51.4-1.51.71.5-1.71.5-1.5-1.3-1.71.7
Post-drug Anxiety3.53.79.2-1.9-2.5-2.5-1.8-0.8-0.50.20.50.50.70.70.91.01.0-3.02.72.6-2.72.9-2.9-1.6-2.32.3
Baseline Anxiety2.73.19.3-2.6-2.5-3.1-2.8-2.7-2.5-1.3-2.0-2.0-1.8-1.8-1.8-1.4-1.4-1.10.40.4-0.40.9-0.80.60.2-0.3
Tail length4.317.044.96.76.66.06.35.55.94.34.14.03.63.63.63.13.22.9-3.1-2.82.9-2.52.21.31.0-0.9
Length with tail8.235.596.19.89.68.68.78.18.56.26.36.15.65.55.54.84.93.8-4.1-3.93.7-3.42.91.71.0-0.9
Length without tail4.915.643.06.66.45.45.55.55.74.34.24.23.93.83.83.43.32.3-2.6-2.62.4-2.11.71.30.5-0.5
Times rat made contact with spout1.21.43.80.81.21.30.8-0.10.0-0.1-0.6-0.6-0.8-0.7-0.8-0.8-0.71.9-2.0-1.51.9-1.61.70.91.7-1.6
Lifetime Intake0.20.20.5-0.6-0.7-0.6-0.5-0.1-0.40.20.00.00.00.10.00.10.1-0.70.70.7-0.70.7-0.6-0.7-0.60.5
Liver weight, left2.33.79.32.53.12.41.71.31.30.30.20.20.0-0.1-0.1-0.2-0.32.6-2.9-2.72.9-2.62.42.32.2-2.1
Liver weight, right1.22.15.22.32.22.12.02.22.01.61.51.61.41.41.41.31.30.7-1.0-0.70.9-0.60.50.20.2-0.1
Locomotor activity1.32.06.52.22.32.62.41.81.81.51.21.20.91.00.90.80.81.2-1.2-0.91.1-1.21.1-0.20.5-0.5
Locomotor testing distance0.51.02.71.31.51.61.30.90.90.70.20.30.00.10.0-0.0-0.01.3-1.4-1.11.4-1.31.20.41.0-1.0
Locomotor testing rearing0.10.20.6-0.10.00.30.10.0-0.30.3-0.5-0.4-0.5-0.5-0.6-0.4-0.40.5-0.8-0.20.7-0.30.3-0.10.6-0.6
Locomotion in novel chamber1.11.43.91.21.51.71.40.40.5-0.6-0.2-0.1-0.4-0.3-0.3-0.6-0.62.0-1.5-1.51.5-1.81.90.91.3-1.3
Locomotion in novel chamber post-restriction0.71.24.81.51.72.22.11.11.10.50.40.60.30.30.30.10.11.5-1.1-0.91.1-1.41.4-0.20.8-0.7
Fecal boli incidents, locomotor time 11.11.65.02.01.92.22.12.01.61.11.11.11.11.11.10.90.91.0-0.8-0.60.8-0.90.8-0.10.3-0.2
Change in fecal boli incidents, locomotor task0.50.51.5-0.8-0.6-1.2-1.2-0.9-0.9-0.7-0.8-0.7-0.9-0.8-0.7-0.7-0.7-0.0-0.3-0.40.30.0-0.00.90.5-0.5
Time >=10cm from walls, locomotor time 11.31.43.3-0.9-1.4-1.0-0.50.2-0.20.80.40.40.60.60.60.80.9-1.71.51.8-1.51.8-1.8-1.6-1.41.4
Bouts of movement, locomotor time 10.91.02.91.61.71.71.51.11.30.91.00.90.70.70.60.50.60.9-0.9-0.90.9-1.00.90.40.4-0.4
Total resting periods, locomotor time 10.91.02.81.71.71.71.51.21.40.91.11.00.80.80.70.60.60.8-0.8-0.80.8-0.90.80.30.3-0.3
Rest time, locomotor task time 11.21.53.41.81.71.71.81.81.81.61.31.31.41.31.31.21.30.2-0.5-0.30.5-0.30.2-0.2-0.10.1
Distance moved, locomotor task time 10.40.61.4-1.1-1.0-0.9-0.9-1.2-1.1-1.0-1.0-0.9-0.9-0.8-0.8-0.8-0.9-0.10.40.3-0.30.1-0.00.20.1-0.1
Vertical activity count, locomotor time 10.00.00.30.10.10.1-0.1-0.1-0.1-0.40.00.0-0.1-0.00.0-0.2-0.30.20.2-0.2-0.1-0.30.30.6-0.00.0
Time >=10cm from walls, locomotor time 21.72.55.10.70.20.31.01.91.32.31.81.81.91.91.82.02.1-1.41.11.4-1.21.6-1.7-1.7-1.61.6
Bouts of movement, locomotor time 21.01.63.41.51.21.61.71.81.71.61.71.71.51.51.41.41.4-0.30.20.3-0.20.2-0.2-1.1-0.70.7
Total resting periods, locomotor time 20.81.43.11.51.21.51.61.81.61.51.61.61.41.41.31.31.4-0.30.10.2-0.10.1-0.2-0.9-0.60.6
Rest time, locomotor task time 20.20.21.2-0.1-0.20.20.30.30.20.70.20.20.30.30.30.40.5-0.70.30.7-0.30.6-0.6-1.1-0.40.4
Distance moved, locomotor task time 21.31.53.3-0.10.3-0.2-0.5-1.1-0.9-1.4-1.2-1.2-1.3-1.2-1.3-1.4-1.41.5-1.2-1.51.3-1.41.41.81.4-1.4
Vertical activity count, locomotor time 21.21.64.11.51.91.31.10.40.6-0.30.10.1-0.2-0.2-0.2-0.5-0.52.0-1.5-2.01.5-2.01.91.91.3-1.3
Light reinforcement 10.51.33.4-1.3-1.6-1.3-0.9-0.6-0.6-0.2-0.0-0.00.20.20.20.30.3-1.71.81.6-1.81.5-1.5-1.2-1.41.4
Light reinforcement 20.40.61.3-0.9-0.7-0.8-0.9-1.1-1.0-1.0-1.0-1.1-1.0-1.0-0.9-1.0-1.00.0-0.1-0.30.2-0.30.40.50.5-0.5
Bone: marrow area0.61.43.41.61.81.81.70.91.10.50.30.30.10.20.1-0.00.01.8-1.5-1.41.5-1.51.50.71.1-1.1
Bone: maximum diameter1.12.14.52.01.71.82.02.12.12.01.81.81.71.71.71.61.60.2-0.2-0.00.10.0-0.1-0.5-0.50.6
Bone: maximum force1.12.05.32.32.32.22.32.02.01.21.31.31.11.11.01.00.91.3-1.1-1.01.0-1.00.90.40.4-0.4
Bone: maximum moment0.91.64.52.12.12.12.11.71.71.01.01.00.80.80.80.70.61.4-1.2-1.11.1-1.11.00.40.6-0.5
Mean time between licks in bursts0.30.82.2-1.5-1.5-1.1-0.9-1.2-1.2-0.7-0.8-0.8-0.8-0.7-0.7-0.6-0.6-0.50.80.8-0.70.6-0.5-0.9-0.30.3
Mean num. licks in bursts1.11.73.60.3-0.20.40.70.90.91.71.31.31.41.41.41.51.5-1.31.21.5-1.31.4-1.4-1.9-1.51.5
Cd content in liver0.30.30.7-0.2-0.10.50.3-0.5-0.4-0.7-0.7-0.6-0.7-0.6-0.7-0.8-0.60.8-0.2-0.20.2-0.80.8-0.40.5-0.5
Co content in liver3.13.66.2-0.20.60.4-0.5-1.3-1.2-1.7-1.9-1.9-2.0-2.0-2.1-2.2-2.12.5-2.2-2.22.2-2.42.41.92.4-2.4
Cu content in liver0.00.00.10.10.10.30.3-0.20.0-0.10.10.00.00.10.0-0.00.00.20.10.1-0.1-0.10.2-0.2-0.10.0
Fe content in liver4.04.87.81.60.81.72.12.72.42.72.62.62.62.72.62.62.8-1.41.71.8-1.81.5-1.6-2.5-2.22.2
K content in liver0.60.51.0-0.1-0.4-0.3-0.00.30.30.70.70.60.70.70.70.70.7-1.01.00.9-1.01.0-1.0-0.8-1.01.0
Mg content in liver0.10.10.30.30.40.30.30.10.1-0.2-0.1-0.1-0.1-0.2-0.2-0.2-0.20.5-0.5-0.50.5-0.50.50.40.4-0.4
Mn content in liver1.21.42.2-0.8-0.4-0.8-1.2-1.4-1.2-1.5-1.4-1.3-1.4-1.4-1.4-1.4-1.40.7-0.9-1.00.9-0.90.91.21.2-1.2
Na content in liver0.50.51.41.11.00.80.91.21.00.80.90.90.80.80.80.70.80.3-0.3-0.30.2-0.20.10.1-0.10.1
Rb content in liver2.02.45.9-2.0-2.4-1.9-1.6-0.7-1.0-0.3-0.1-0.00.10.10.10.20.3-2.12.42.2-2.32.0-1.9-1.5-1.81.7
Se content in liver6.57.711.91.30.20.61.52.62.53.33.33.23.43.33.43.43.4-2.62.52.6-2.62.8-2.9-2.6-3.13.2
Sr content in liver1.11.02.30.30.70.1-0.2-0.7-0.3-0.9-0.7-0.7-0.8-0.8-0.8-0.9-0.91.2-1.3-1.51.4-1.31.21.51.3-1.3
Zn content in liver1.51.65.02.12.22.01.81.51.60.90.90.90.80.70.70.50.51.4-1.3-1.31.2-1.31.20.80.7-0.7
Bone: minimum diameter0.10.20.6-0.3-0.1-0.1-0.2-0.4-0.4-0.3-0.6-0.6-0.6-0.6-0.7-0.6-0.60.8-0.5-0.30.5-0.40.40.40.6-0.6
Time in familiar zone, hab. session 10.60.61.5-0.7-0.5-0.8-0.9-1.2-0.9-0.7-0.9-1.0-0.9-0.9-0.9-0.7-0.80.2-0.6-0.30.6-0.10.10.60.7-0.7
Time in novel zone, hab. session 10.30.30.60.70.60.60.80.80.80.50.80.80.70.70.70.60.60.00.10.0-0.20.0-0.1-0.1-0.30.3
Total zone transitions, hab. session 10.60.82.0-1.2-1.4-1.0-1.1-0.8-0.8-0.8-0.2-0.3-0.1-0.2-0.1-0.2-0.2-1.11.41.1-1.30.9-0.8-0.8-0.90.9
Total locomotion distance, hab. session 11.62.35.8-0.7-1.3-0.9-0.50.50.20.31.11.01.21.11.21.21.1-2.22.42.0-2.42.0-2.0-1.7-2.12.1
Locomotion velocity, hab. session 11.72.46.8-1.3-1.8-1.3-0.90.0-0.3-0.10.70.60.80.80.80.80.8-2.32.62.2-2.52.1-2.0-1.8-2.12.1
Time in familiar zone, hab. session 20.10.10.4-0.2-0.3-0.5-0.3-0.0-0.10.10.10.10.20.20.20.30.2-0.60.30.4-0.30.6-0.6-0.1-0.30.3
Time in novel zone, hab. session 20.10.10.3-0.4-0.3-0.1-0.1-0.5-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.4-0.30.20.10.1-0.1-0.10.1-0.20.1-0.1
Total zone transitions, hab. session 20.60.71.40.20.60.30.0-0.7-0.4-0.8-0.7-0.6-0.7-0.8-0.8-0.9-0.91.2-1.0-1.11.0-1.21.21.01.1-1.1
Total locomotion distance, hab. session 20.10.10.3-0.4-0.4-0.3-0.4-0.5-0.4-0.5-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.00.30.1-0.2-0.00.0-0.0-0.10.1
Locomotion velocity, hab. session 20.10.10.5-0.4-0.3-0.3-0.5-0.5-0.5-0.7-0.3-0.4-0.3-0.4-0.4-0.4-0.40.10.2-0.1-0.2-0.10.20.20.1-0.1
Novel to familiar place preference ratio0.80.91.4-0.4-0.0-0.2-0.5-0.6-0.7-0.9-1.2-1.1-1.2-1.1-1.2-1.1-1.10.9-1.1-0.91.1-0.90.90.81.2-1.2
Novelty place preference0.91.01.8-0.7-0.4-0.5-0.7-0.8-1.0-1.1-1.4-1.3-1.3-1.3-1.4-1.3-1.20.8-0.9-0.80.9-0.80.80.71.1-1.1
Time in novel zone, NPP test0.70.81.3-0.5-0.2-0.3-0.5-0.6-0.8-0.9-1.2-1.1-1.1-1.1-1.2-1.1-1.00.8-0.9-0.70.9-0.70.80.71.0-1.1
Total zone transitions, NPP test0.00.00.20.30.30.40.4-0.10.20.00.10.10.10.10.10.00.10.3-0.0-0.10.0-0.20.3-0.00.0-0.0
Total locomotion distance, NPP test1.31.83.10.2-0.40.20.60.70.91.21.41.41.41.41.41.41.5-1.41.71.6-1.71.4-1.4-1.8-1.71.7
Locomotion velocity, NPP test0.91.32.60.3-0.10.50.70.70.91.01.31.21.31.31.31.21.3-1.01.41.3-1.41.0-1.0-1.6-1.41.4
Intraocular pressure1.82.65.42.11.82.22.22.32.32.02.12.01.91.91.91.81.80.10.20.2-0.20.0-0.1-0.8-0.80.8
Delta distance traveled before/after self-admin0.40.41.10.81.00.80.4-0.00.4-0.30.20.20.00.0-0.0-0.2-0.20.9-0.7-1.00.7-1.01.01.10.6-0.6
Delta ambulatory time before/after self-admin0.20.20.6-0.10.1-0.1-0.4-0.7-0.4-0.8-0.4-0.4-0.5-0.5-0.5-0.6-0.60.5-0.4-0.60.4-0.60.60.70.5-0.5
Parametrial fat weight0.30.81.60.2-0.2-0.6-0.00.60.61.21.00.81.01.01.01.11.2-1.10.80.7-0.91.2-1.3-0.4-1.01.0
Pavlov. Cond. lever latency1.31.63.91.72.01.51.30.80.90.30.10.10.00.0-0.0-0.1-0.11.7-1.9-1.81.9-1.61.51.61.4-1.4
Pavlov. Cond. magazine entry latency0.20.30.80.70.70.90.80.60.80.80.50.50.50.50.50.40.50.2-0.2-0.10.2-0.20.2-0.4-0.00.1
Pavlov. Cond. change in total contacts0.91.02.4-0.8-1.1-1.0-0.8-0.4-0.10.40.40.40.50.50.60.60.7-1.61.51.3-1.51.4-1.4-1.1-1.31.3
Pavlov. Cond. index score0.40.51.4-0.2-0.5-0.10.00.10.20.60.60.50.60.60.60.60.7-1.01.01.0-1.00.9-0.9-1.2-1.01.0
Pavlov. Cond. latency score0.50.71.7-0.5-0.8-0.4-0.2-0.00.00.50.50.40.50.50.50.60.6-1.11.21.2-1.21.1-1.0-1.3-1.11.1
Pavlov. Cond. lever contacts1.21.43.3-1.5-1.8-1.4-1.2-0.7-0.8-0.1-0.1-0.10.00.10.10.10.2-1.61.81.7-1.71.5-1.5-1.5-1.31.3
Pavlov. Cond. magazine entry number0.40.51.2-0.7-0.5-1.0-1.0-0.7-0.9-1.1-0.8-0.8-0.8-0.9-0.8-0.8-0.90.3-0.3-0.50.4-0.20.31.10.6-0.6
Pavlov. Cond. intertrial magazine entries0.70.92.2-1.2-1.0-0.7-1.0-1.5-1.2-1.0-1.3-1.2-1.3-1.2-1.2-1.2-1.10.2-0.1-0.00.1-0.30.4-0.10.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.61.4-0.2-0.5-0.2-0.00.10.20.60.60.50.60.60.60.60.7-1.01.01.0-1.01.0-0.9-1.2-1.01.0
Pavlov. Cond. response bias0.40.51.40.40.10.60.60.60.70.90.80.80.80.80.80.80.9-0.60.70.7-0.70.5-0.5-1.2-0.80.8
Pavlov. Cond. lever latency0.81.02.30.10.5-0.1-0.3-0.9-0.5-0.9-0.9-0.9-1.0-1.0-1.0-1.0-1.01.2-1.3-1.31.3-1.21.11.51.3-1.3
Pavlov. Cond. magazine entry latency1.31.63.7-1.3-1.7-1.2-1.00.0-0.40.30.20.20.40.40.40.50.4-1.91.91.9-1.91.8-1.7-1.7-1.61.6
Pavlov. Cond. change in total contacts0.20.30.9-0.1-0.30.20.20.50.20.30.40.30.40.40.40.30.3-0.50.80.7-0.80.4-0.4-1.0-0.70.7
Pavlov. Cond. index score0.81.02.7-0.8-1.1-0.5-0.30.4-0.10.40.40.40.50.50.50.60.5-1.41.61.6-1.61.3-1.3-1.6-1.41.4
Pavlov. Cond. latency score0.91.12.8-0.8-1.2-0.6-0.30.5-0.00.50.50.50.60.60.60.60.6-1.51.71.6-1.71.4-1.4-1.6-1.51.4
Pavlov. Cond. lever contacts1.11.53.4-0.2-0.7-0.00.31.10.61.11.01.01.11.11.11.21.1-1.51.61.7-1.61.5-1.4-1.8-1.61.6
Pavlov. Cond. magazine entry number0.81.02.51.21.51.11.00.10.60.20.10.1-0.0-0.1-0.1-0.1-0.11.5-1.6-1.41.6-1.31.21.31.2-1.2
Pavlov. Cond. intertrial magazine entries0.61.02.31.01.31.41.00.20.5-0.1-0.2-0.2-0.3-0.2-0.3-0.4-0.31.5-1.5-1.31.4-1.41.41.01.2-1.2
Pavlov. Cond. lever-magazine prob. diff.0.70.92.5-0.9-1.2-0.6-0.40.3-0.20.20.30.30.30.40.40.40.4-1.31.61.5-1.61.2-1.2-1.5-1.31.3
Pavlov. Cond. response bias1.52.14.8-0.6-1.1-0.3-0.00.90.41.01.01.01.11.11.11.21.1-1.92.12.1-2.11.8-1.8-2.2-2.02.0
Time in closed arm before self-admin0.91.23.21.51.81.31.30.40.8-0.30.20.20.10.10.1-0.3-0.11.7-1.3-1.71.3-1.71.61.21.0-1.0
Time in closed arm after self-admin1.82.05.11.62.02.11.40.50.7-0.30.00.0-0.2-0.2-0.2-0.6-0.52.3-1.8-1.91.8-2.22.21.01.5-1.5
Time in open arm before self-admin0.10.10.30.20.20.40.30.50.20.40.40.30.30.30.20.20.2-0.10.10.2-0.10.0-0.0-0.4-0.20.2
Time in open arm after self-admin1.11.23.0-1.4-1.7-1.5-1.0-0.5-0.50.4-0.1-0.10.10.00.10.40.4-1.71.41.6-1.41.7-1.7-1.1-1.21.2
Bone: periosteal estimation1.02.15.32.32.22.22.32.12.11.61.51.51.31.31.21.21.21.1-0.9-0.70.8-0.80.70.10.1-0.1
Bone: periosteal perimeter1.62.75.41.61.11.72.12.12.12.32.02.01.92.01.91.92.0-0.40.70.9-0.80.7-0.8-1.7-1.31.3
Bone: post-yield work0.91.32.11.00.61.01.21.41.41.21.41.41.41.51.41.41.4-0.60.80.8-0.80.6-0.7-0.9-1.11.1
Progressive ratio test 1 active lever presses0.50.61.71.31.31.11.00.90.90.60.80.80.70.70.70.50.50.7-0.5-0.70.5-0.70.60.50.2-0.2
Progressive ratio test 1 breakpoint0.50.61.71.31.31.11.00.90.90.60.80.80.70.70.70.50.50.7-0.5-0.70.5-0.70.60.50.2-0.2
Progressive ratio test 1 inactive lever presses0.81.23.01.01.31.20.80.20.2-0.3-0.3-0.4-0.4-0.4-0.5-0.7-0.61.7-1.5-1.51.5-1.71.71.11.3-1.3
Progressive ratio test 2 active lever presses0.60.82.21.31.51.20.90.70.70.10.40.30.20.30.1-0.1-0.01.3-0.9-1.20.9-1.31.20.80.7-0.7
Progressive ratio test 2 breakpoint0.60.71.91.21.41.20.80.60.60.10.30.30.10.20.0-0.1-0.11.3-0.9-1.20.9-1.31.20.80.7-0.7
Progressive ratio test 2 inactive lever presses1.62.67.02.22.62.72.11.51.51.00.50.50.30.40.20.00.02.4-2.0-1.82.0-2.12.00.61.4-1.4
Incentive Sensitization - Responses0.10.10.3-0.10.0-0.2-0.4-0.3-0.3-0.4-0.3-0.3-0.4-0.3-0.5-0.4-0.50.4-0.1-0.40.2-0.40.40.50.3-0.3
Incentive Sensitization - Breakpoint0.10.10.3-0.2-0.1-0.2-0.5-0.3-0.3-0.4-0.3-0.3-0.4-0.3-0.5-0.4-0.50.3-0.0-0.30.1-0.30.30.40.2-0.2
Sum of active levers in priming session hrs 5-62.12.03.20.4-0.1-0.40.21.01.11.11.71.61.71.61.71.71.7-1.71.61.2-1.61.6-1.7-0.7-1.81.8
Progressive ratio1.32.14.1-1.4-1.0-1.2-1.4-1.9-1.7-1.8-1.9-2.0-1.9-1.8-1.9-1.8-1.80.8-0.8-0.70.8-0.70.81.11.2-1.3
Food seeking constrained by brief footshock0.70.91.8-1.2-1.0-1.1-1.3-1.2-1.3-1.2-1.1-1.3-1.2-1.2-1.1-1.1-1.10.1-0.1-0.10.2-0.10.10.50.5-0.5
Seeking ratio, punishment vs. effort0.50.81.91.21.01.01.01.41.11.01.31.21.11.11.21.01.0-0.10.10.0-0.10.0-0.1-0.3-0.40.5
Retroperitoneal fat weight1.25.19.9-0.2-1.1-1.1-0.01.51.02.02.12.02.22.22.32.42.3-3.12.72.7-2.83.1-3.1-2.2-2.92.9
Reaction time number correct0.40.71.91.21.41.41.00.50.8-0.10.30.30.10.10.1-0.1-0.11.3-0.9-1.10.9-1.31.20.80.7-0.7
Reaction time mean minus median0.92.36.10.5-0.00.91.31.41.32.21.51.61.61.71.61.71.8-1.21.21.7-1.31.4-1.4-2.5-1.61.6
Reaction time mean minus median AUC0.20.53.8-0.4-0.60.40.40.00.10.80.10.30.20.40.30.40.5-0.60.71.2-0.70.7-0.6-1.9-0.70.7
Reaction time num false alarms0.10.21.2-0.1-0.30.40.50.30.20.50.1-0.00.10.20.10.20.3-0.20.40.7-0.40.3-0.3-1.1-0.40.4
Reaction time num false alarms AUC0.30.52.10.2-0.10.70.90.70.61.00.60.40.60.70.60.70.7-0.40.60.9-0.60.5-0.5-1.4-0.70.7
Reaction time trials correct on left0.40.71.91.21.41.41.00.50.8-0.10.30.30.10.10.1-0.1-0.11.3-0.9-1.10.9-1.31.20.80.7-0.7
Reaction time trials on left0.40.71.81.11.31.41.00.50.7-0.10.20.20.00.10.0-0.1-0.11.3-0.9-1.00.9-1.21.20.80.7-0.7
Reaction time mean1.21.95.7-2.2-2.4-2.1-1.9-1.5-1.6-0.5-1.0-0.8-0.7-0.6-0.7-0.4-0.4-1.81.41.6-1.31.6-1.4-1.3-0.80.8
Reaction time mean AUC1.21.95.5-2.1-2.4-2.0-1.8-1.4-1.6-0.4-0.8-0.7-0.6-0.5-0.6-0.3-0.2-1.91.51.7-1.51.6-1.5-1.4-1.00.9
Median of all reaction times2.23.18.3-2.9-2.9-2.9-2.8-2.3-2.5-1.4-1.7-1.5-1.4-1.3-1.4-1.1-1.1-1.81.21.3-1.21.4-1.3-0.7-0.50.4
Reaction time omissions0.40.52.6-0.9-1.1-0.5-0.4-0.5-0.60.4-0.2-0.3-0.10.1-0.20.10.2-1.00.71.2-0.80.9-0.9-1.6-0.60.6
Reaction time false alarm rate0.60.83.3-0.3-0.60.10.50.60.41.10.60.40.70.80.70.80.9-1.01.01.4-1.11.1-1.1-1.8-1.11.1
Reaction time premature initiation rate0.10.10.3-0.1-0.3-0.0-0.00.40.10.20.20.10.30.20.20.30.3-0.50.50.5-0.50.4-0.4-0.5-0.50.5
Reaction time premature initiations0.00.10.20.30.30.50.30.50.40.10.20.20.20.20.20.20.20.00.10.1-0.1-0.10.1-0.1-0.20.2
Std. dev. reaction times0.61.24.5-0.7-1.1-0.4-0.10.10.11.10.40.60.60.70.60.80.9-1.41.31.7-1.31.5-1.5-2.1-1.31.3
Reaction time trials completed0.40.71.81.11.31.41.00.50.7-0.10.20.20.00.10.0-0.1-0.11.3-0.9-1.00.9-1.21.20.80.7-0.7
Reaction time trials AUC0.30.51.51.01.11.20.90.50.7-0.10.30.20.10.10.1-0.1-0.11.1-0.7-0.80.7-1.01.00.60.5-0.5
Run reversals in cocaine runway, females0.60.61.6-0.7-1.0-0.9-0.6-0.2-0.20.00.20.30.40.30.40.40.4-1.31.21.0-1.21.1-1.1-0.7-1.01.0
Run reversals in cocaine runway, males0.90.91.9-0.10.20.60.1-0.8-0.7-1.0-1.0-1.1-1.1-1.1-1.1-1.2-1.11.3-1.0-0.91.0-1.31.40.51.2-1.2
Latency to leave start box in cocaine runway0.10.10.7-0.4-0.4-0.8-0.7-0.7-0.3-0.4-0.4-0.2-0.3-0.4-0.3-0.3-0.3-0.4-0.0-0.10.00.2-0.20.30.1-0.1
Latency to leave start box in cocaine runway, F0.20.21.60.10.3-0.6-0.6-0.4-0.0-0.5-0.2-0.1-0.2-0.3-0.1-0.2-0.30.0-0.5-0.80.5-0.30.21.30.5-0.5
Latency to leave start box in cocaine runway, M0.20.20.9-0.6-0.7-0.3-0.2-0.5-0.40.1-0.3-0.2-0.2-0.2-0.2-0.1-0.1-0.40.50.6-0.50.4-0.4-0.9-0.30.3
Std. dev. time between licks in bursts0.30.41.30.70.61.11.10.80.70.80.50.50.50.60.50.50.50.30.00.2-0.0-0.20.2-1.0-0.20.2
Total sessions with >9 infusions0.20.30.9-0.8-0.7-0.9-0.8-0.6-0.8-0.4-0.6-0.6-0.6-0.5-0.6-0.4-0.5-0.30.10.1-0.10.2-0.20.20.1-0.1
Short access day 1 total inactive lever presses0.20.30.9-0.00.20.1-0.10.0-0.30.2-0.6-0.6-0.6-0.6-0.7-0.5-0.60.8-1.0-0.60.9-0.50.50.30.8-0.8
Short access day 10 total inactive lever presses0.40.92.41.31.60.80.70.50.80.90.30.30.20.10.10.10.21.3-1.5-1.41.4-1.00.91.41.0-1.0
Short access day 1 total infusions0.60.72.3-1.4-1.4-1.5-1.3-1.0-1.3-0.4-0.9-0.9-0.8-0.7-0.9-0.5-0.6-0.70.50.6-0.40.7-0.7-0.3-0.10.1
Short access day 10 total infusions0.60.71.7-0.5-0.8-0.6-0.30.2-0.10.70.50.50.50.50.50.60.6-1.31.11.2-1.11.2-1.2-1.3-1.11.1
Short access total infusions0.60.82.6-1.3-1.5-1.6-1.5-0.7-1.1-0.1-0.4-0.4-0.4-0.4-0.4-0.1-0.2-1.20.90.9-0.81.1-1.1-0.4-0.60.5
Short access day 1 locomotion0.20.21.2-0.6-0.8-0.2-0.20.1-0.40.3-0.2-0.2-0.2-0.1-0.2-0.0-0.0-0.50.50.8-0.50.5-0.5-1.1-0.30.3
Short access day 10 total locomotion0.10.20.4-0.10.00.30.2-0.2-0.40.1-0.5-0.5-0.5-0.5-0.5-0.4-0.30.4-0.6-0.20.6-0.40.4-0.10.6-0.6
Short access total locomotion0.40.51.4-1.0-1.2-0.8-0.6-0.4-0.70.2-0.3-0.3-0.2-0.1-0.10.00.1-1.00.81.0-0.80.9-0.9-0.9-0.60.6
One hour access (0.3 mA shock)1.71.95.51.31.71.91.30.30.5-0.2-0.5-0.5-0.6-0.5-0.7-0.8-0.82.3-1.9-1.81.9-2.22.20.71.7-1.7
Compulsive drug intake1.31.63.7-1.8-1.6-1.5-1.4-1.8-1.7-1.9-1.6-1.6-1.4-1.5-1.4-1.3-1.4-0.40.40.3-0.30.2-0.00.20.2-0.3
One hour access (shock baseline)1.11.65.62.02.02.41.91.71.61.41.01.00.81.00.70.60.71.4-1.0-0.80.9-1.11.1-0.30.5-0.4
Social response proportion1.92.16.62.52.62.22.01.71.90.81.41.31.11.11.10.80.71.4-1.2-1.51.2-1.41.31.00.6-0.6
Social responses1.52.05.52.22.02.42.31.82.01.51.61.51.51.51.41.21.30.8-0.4-0.40.3-0.70.6-0.4-0.20.2
Social time1.62.16.0-2.1-1.8-1.6-1.9-2.4-2.2-1.8-1.8-1.8-1.7-1.7-1.7-1.6-1.6-0.20.20.2-0.10.00.10.20.5-0.5
Soleus weight1.95.710.82.92.42.73.03.23.33.03.23.23.03.03.02.82.8-0.20.50.5-0.60.4-0.6-1.2-1.41.5
Bone: stiffness0.40.61.81.21.11.31.31.21.10.70.80.80.70.70.60.60.60.6-0.3-0.30.3-0.40.4-0.2-0.00.0
Tibialis anterior weight5.117.336.26.05.25.15.56.06.05.25.45.35.04.94.94.64.60.4-0.4-0.40.2-0.2-0.2-1.0-1.51.6
Time to tail flick, vehicle, before self-admin0.90.92.5-0.8-1.1-1.4-1.2-0.0-0.6-0.60.3-0.10.50.50.40.40.5-1.61.51.0-1.41.3-1.3-0.0-1.21.2
Time to tail flick, vehicle, after self-admin0.00.00.1-0.1-0.1-0.0-0.1-0.3-0.0-0.20.00.20.0-0.10.0-0.1-0.1-0.10.20.1-0.20.0-0.00.2-0.10.1
Time to tail flick, test, before self-admin1.21.22.81.41.71.21.00.60.70.10.20.3-0.1-0.1-0.1-0.2-0.21.6-1.5-1.71.5-1.51.41.61.2-1.2
Time to tail flick, test, after self-admin0.40.41.4-0.6-0.8-1.2-0.8-0.6-0.3-0.30.1-0.00.20.10.10.20.2-1.11.00.6-1.00.9-0.90.0-0.80.8
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.1-0.00.40.4-0.40.10.3-0.20.1-0.3-0.3-0.2-0.2-0.20.3-0.10.10.1-0.20.2-0.40.2-0.2
Delta time to tail flick, test, before/after SA1.11.12.6-1.3-1.6-1.4-1.1-0.8-0.7-0.2-0.3-0.40.0-0.00.00.10.2-1.61.51.4-1.41.4-1.4-1.0-1.11.1
Tibia length1.85.015.23.53.92.72.32.32.20.51.01.00.80.60.70.40.32.6-2.9-3.12.8-2.62.42.71.9-1.9
Ambulatory time before self-admin0.60.92.3-0.3-0.7-0.10.40.70.30.90.70.50.80.80.80.80.9-1.21.31.5-1.31.3-1.2-1.5-1.31.3
Ambulatory time after self-admin0.50.61.30.1-0.20.20.40.50.50.60.80.80.80.90.80.80.9-0.81.11.0-1.10.8-0.8-1.0-1.11.1
Bone: tissue strength0.20.20.50.10.3-0.0-0.0-0.5-0.2-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.5-0.7-0.70.7-0.60.50.70.6-0.6
Total heroin consumption2.12.56.4-1.4-2.0-1.2-1.0-0.3-0.30.20.60.50.60.70.70.80.8-2.42.52.4-2.52.2-2.1-1.9-2.12.1
Bone: trabecular number2.84.711.03.02.62.42.83.33.12.82.82.82.72.62.62.52.5-0.1-0.2-0.10.00.2-0.4-0.3-0.90.9
Bone: trabecular spacing2.22.97.2-2.7-2.5-2.2-2.5-2.6-2.4-2.0-2.0-2.0-1.8-1.8-1.8-1.7-1.6-0.60.80.8-0.70.5-0.4-0.40.1-0.1
Bone: trabecular thickness5.67.014.23.22.52.63.33.83.53.53.53.53.43.33.33.23.2-0.60.60.6-0.70.8-1.0-1.4-1.71.7
Bone: trabecular tissue density0.71.01.80.3-0.10.20.61.00.71.01.11.11.11.11.11.11.2-1.11.11.1-1.11.1-1.1-1.3-1.21.2
Water consumed over 24 hours3.04.19.81.52.21.91.10.30.2-0.6-0.9-0.9-1.1-1.1-1.2-1.3-1.23.0-3.1-2.83.1-2.92.92.32.7-2.7
Number of responses in last shaping day0.20.20.5-0.7-0.7-0.5-0.5-0.5-0.60.0-0.5-0.6-0.5-0.4-0.6-0.3-0.2-0.30.10.3-0.10.3-0.2-0.40.1-0.1