Hub : Genes

Ltbp3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_006230906.4 0.05 0.03 4.2e-03 0 0.02 0.01 0.01 1.6e-01 3.9e-03 1.7e-02 3.5e-02
2 Brain mRNA stability Ltbp3 0.05 0.03 3.7e-05 0.04 0.05 0.04 0.01 1.4e-04 1.3e-05 4.9e-05 1.9e-02
3 Liver gene expression Ltbp3 0.04 0.02 9.3e-04 0.01 0.01 0 0.01 3.1e-02 4.0e-02 1.2e-01 1.9e-02
4 Adipose gene expression Ltbp3 0.1 0.06 5.9e-06 0.03 0.04 0.03 0.04 1.0e-04 6.2e-05 2.0e-04 7.4e-05
5 LHb gene expression Ltbp3 0.41 0.14 4.5e-07 0.23 0.1 0.22 0 2.6e-06 2.0e-03 7.6e-06 2.4e-01
6 pVTA gene expression Ltbp3 0.46 0.16 5.4e-13 0.2 0.19 0.16 0.2 3.8e-09 1.5e-08 1.9e-07 6.6e-09
7 RMTg gene expression Ltbp3 0.18 0.13 4.5e-03 0.12 0.06 0.08 0.1 5.4e-04 9.2e-03 4.6e-03 1.1e-03
8 NAcc gene expression Ltbp3 0.11 0.06 9.6e-11 0.1 0.09 0.09 0.1 4.2e-11 1.5e-10 3.0e-10 3.6e-11
9 IL gene expression Ltbp3 0.49 0.15 3.8e-06 0.16 0.13 0.17 0.16 9.8e-05 5.5e-04 8.0e-05 9.4e-05
10 BLA gene expression Ltbp3 0.44 0.12 0.0e+00 0.32 0.34 0.31 0.36 1.8e-17 1.2e-18 2.9e-17 3.5e-20
11 Brain gene expression Ltbp3 0.49 0.11 0.0e+00 0.47 0.42 0.51 0.44 1.1e-48 9.6e-42 2.6e-54 2.6e-44
12 PL gene expression Ltbp3 0.44 0.13 0.0e+00 0.3 0.35 0.36 0.36 2.1e-33 1.8e-39 2.2e-41 1.5e-41
13 OFC gene expression Ltbp3 0.34 0.14 1.5e-04 0.08 0.16 0.26 0.26 6.3e-03 1.7e-04 6.3e-07 7.4e-07
14 Adipose mRNA stability Ltbp3 0.35 0.13 3.0e-08 0.04 0.07 0.06 0.07 1.6e-05 1.3e-08 1.2e-07 8.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density1.42.34.1-0.90.90.30.81.12.02.0-1.91.9-1.91.8-1.91.41.4
Area under the delay curve0.90.93.30.30.71.61.00.90.60.6-0.80.8-0.70.8-1.01.80.8
BMI with tail3.812.224.3-3.10.9-0.61.01.34.94.9-4.94.6-4.24.2-4.02.42.6
BMI without tail1.53.06.4-1.40.4-0.60.50.52.52.5-2.42.3-2.22.2-1.90.91.2
Body weight1.24.915.3-3.9-1.9-2.6-1.9-1.62.92.9-2.72.1-1.61.6-1.4-0.00.5
Weight adjusted by age0.70.83.2-1.8-1.4-1.4-1.5-1.00.50.5-0.50.20.1-0.10.1-0.7-0.1
Bone surface2.23.910.7-3.3-0.7-1.5-1.1-0.52.82.8-2.52.3-2.01.8-1.80.51.3
Bone volume2.03.36.5-2.30.3-0.4-0.00.52.62.6-2.32.3-2.22.0-2.11.21.7
Breakpoint value in progressive ratio session1.11.25.4-2.3-1.4-0.9-1.4-1.01.31.3-1.10.8-0.60.3-0.60.30.6
Number of licking bursts0.20.20.7-0.8-0.3-0.4-0.3-0.40.60.6-0.60.5-0.40.3-0.30.10.4
Context. condit. distance diff. score0.70.92.91.71.31.41.51.4-0.5-0.50.6-0.3-0.00.1-0.20.70.1
Locomotion velocity, session 10.50.61.30.5-0.5-0.5-0.4-0.7-0.8-0.80.9-0.80.8-0.80.8-0.8-1.1
Locomotion distance, session 10.50.61.5-0.50.3-0.00.40.11.21.2-0.80.9-1.11.1-1.00.70.4
Locomotion velocity, session 21.01.23.1-1.8-0.8-1.1-0.7-0.71.51.5-1.51.1-0.90.9-0.80.20.4
Locomotion distance, session 20.40.51.1-0.6-0.1-0.10.10.01.11.1-0.90.7-0.91.0-0.80.70.4
Locomotion velocity, session 30.60.61.20.41.10.51.10.70.70.7-0.91.0-0.90.9-0.90.60.2
Locomotion distance, session 30.00.00.10.30.20.30.20.2-0.2-0.20.0-0.10.0-0.00.00.2-0.1
Stereotopy head waving bouts, day 30.50.61.81.11.30.81.30.80.50.5-0.30.7-0.70.8-0.70.6-0.3
Stereotopy head waving duration, day 30.30.41.41.11.20.61.10.50.30.3-0.10.5-0.60.6-0.50.2-0.1
Locomotion velocity, session 72.83.05.20.31.81.81.92.31.41.4-1.51.7-1.81.9-1.92.21.6
Locomotion distance, session 70.50.61.90.50.71.01.01.40.50.5-0.30.3-0.60.7-0.81.20.4
Stereotopy head waving bouts, day 70.80.91.7-0.20.90.50.80.80.90.9-1.31.3-1.11.1-1.00.81.1
Stereotopy head waving duration, day 71.41.73.9-1.50.0-0.7-0.1-0.11.71.7-2.01.9-1.41.4-1.20.31.3
Locomotion velocity, session 81.01.22.6-0.3-1.3-1.5-1.3-1.5-0.7-0.70.4-0.71.1-1.01.2-1.3-1.6
Locomotion distance, session 80.50.81.60.41.11.01.11.30.70.7-0.50.6-0.91.0-1.01.20.4
Degree of sensitization distance0.60.61.40.20.80.80.81.20.70.7-0.30.5-0.70.8-0.91.10.3
Degree of sensitization stereotypy1.01.12.9-1.40.1-0.3-0.10.11.31.3-1.71.5-1.11.0-1.00.41.3
Conditioned locomotion0.60.71.9-1.1-1.3-1.4-1.3-1.10.20.20.1-0.20.3-0.40.4-0.8-0.6
Cocaine response after cond. corrected0.70.83.61.90.90.81.00.6-1.0-1.00.8-0.60.6-0.50.5-0.2-0.9
Cocaine response after cond. not corrected0.60.62.91.70.80.60.80.3-0.9-0.90.7-0.60.5-0.40.5-0.3-1.0
Cocaine response before conditioning0.40.41.6-1.3-0.5-0.8-0.7-0.70.70.7-0.80.5-0.40.4-0.3-0.10.4
Saline control response1.11.54.2-1.8-1.9-2.0-1.9-2.00.60.6-0.50.10.2-0.10.3-0.8-0.9
Bone: connectivity density1.62.55.3-2.0-0.1-0.6-0.20.32.32.3-2.22.0-1.81.7-1.71.01.1
Bone: cortical apparent density0.10.10.6-0.5-0.8-0.5-0.5-0.40.00.00.0-0.00.2-0.10.1-0.10.5
Bone: cortical area0.30.41.9-1.4-0.7-0.9-0.9-0.90.50.5-0.30.3-0.20.1-0.1-0.50.1
Bone: cortical porosity0.40.51.3-0.40.4-0.10.40.20.90.9-1.11.0-0.80.8-0.70.40.6
Bone: cortical porosity0.40.41.2-0.7-0.2-0.7-0.2-0.30.90.9-1.10.9-0.60.6-0.50.00.3
Bone: cortical thickness1.52.56.6-1.8-2.6-2.2-2.4-2.3-0.4-0.40.5-0.91.1-1.41.2-1.6-1.0
Bone: cortical thickness1.51.72.4-0.1-1.5-1.3-1.3-1.4-1.1-1.11.4-1.41.4-1.51.4-1.6-1.4
Bone: cortical tissue density0.10.20.9-0.6-0.9-0.6-0.6-0.6-0.0-0.00.1-0.10.3-0.20.3-0.20.4
Condit. Reinf. active minus inactive responses0.20.20.4-0.4-0.10.10.1-0.00.50.5-0.50.5-0.40.5-0.50.60.5
Condit. Reinf. active-inactive response ratio0.00.00.2-0.2-0.2-0.10.0-0.30.10.1-0.10.2-0.10.1-0.10.20.5
Condit. Reinf. active responses0.40.50.8-0.40.40.40.50.40.90.9-0.60.7-0.80.9-0.90.90.7
Condit. Reinf. inactive responses0.70.81.3-0.21.00.80.81.01.01.0-0.50.7-1.01.1-1.11.00.6
Incentive salience index mean0.50.61.2-0.70.20.10.30.21.11.1-0.90.9-1.01.0-1.00.90.7
Condit. Reinf. lever presses0.30.41.0-0.90.1-0.30.0-0.01.01.0-0.60.6-0.80.9-0.80.30.4
Condit. Reinf. active minus inactive responses0.50.71.6-0.20.71.10.61.30.50.5-0.60.7-0.70.7-0.91.21.0
Condit. Reinf. active-inactive response ratio1.41.52.8-0.11.41.61.11.70.80.8-0.91.2-1.21.2-1.31.61.2
Condit. Reinf. active responses0.50.71.4-0.50.40.70.41.00.80.8-0.91.0-0.90.9-1.01.21.2
Condit. Reinf. inactive responses0.10.10.2-0.2-0.2-0.3-0.0-0.10.40.4-0.40.4-0.20.3-0.20.20.4
Condit. Reinf. lever presses0.91.35.4-2.3-0.9-0.7-1.1-0.21.31.3-1.51.2-0.80.8-0.70.60.9
Condit. Reinf. lever reinforcers received0.40.61.3-0.90.00.40.00.60.90.9-0.90.9-0.80.8-0.81.01.1
Conditioned reinforcement - actives0.10.10.3-0.10.20.1-0.10.1-0.5-0.50.4-0.30.3-0.30.3-0.30.0
Conditioned reinforcement - inactives1.82.07.21.91.92.71.72.0-1.1-1.11.3-0.70.2-0.3-0.11.20.8
Conditioned locomotion2.42.97.82.81.92.01.61.6-2.2-2.22.1-1.51.1-1.10.9-0.1-0.3
Patch foraging indifference point 0 sec0.00.10.10.10.30.30.30.30.10.10.00.0-0.20.1-0.20.40.3
Patch foraging indifference point AUC1.21.45.9-2.4-1.7-1.7-1.8-1.11.01.0-0.90.6-0.20.0-0.1-0.50.4
Delay disc. indifference point, 0s delay0.80.92.71.01.11.71.30.90.00.0-0.50.7-0.40.8-0.61.60.4
Delay disc. indifference point, 16s delay1.71.73.70.51.31.91.41.70.90.9-0.81.0-1.31.0-1.51.91.5
Delay disc. indifference point, 2s delay0.20.20.40.30.60.50.60.60.20.2-0.30.3-0.40.4-0.40.50.2
Delay disc. indifference point, 24s delay0.30.30.60.7-0.20.5-0.0-0.3-0.6-0.60.5-0.60.6-0.60.50.1-0.7
Delay disc. indifference point, 4s delay0.30.31.00.90.61.00.80.5-0.1-0.1-0.20.1-0.10.3-0.30.8-0.1
Delay disc. indifference point, 8s delay0.40.42.10.60.31.50.50.3-0.1-0.1-0.10.1-0.00.2-0.31.4-0.0
Indifference point function ln k2.94.017.24.12.52.62.71.7-2.0-2.02.2-1.40.8-0.60.60.3-1.0
Indifference point function log k2.94.017.24.12.52.62.71.7-2.0-2.02.2-1.40.8-0.60.60.3-1.0
Patch foraging total patch changes 0 sec0.10.10.30.3-0.1-0.1-0.1-0.2-0.4-0.40.5-0.50.4-0.50.4-0.2-0.4
Patch foraging total patch changes 12 sec1.51.97.5-2.7-1.7-1.8-1.6-1.11.61.6-1.51.1-0.70.4-0.6-0.10.7
Patch foraging total patch changes 18 sec0.50.61.4-1.2-0.2-0.4-0.2-0.01.11.1-1.10.9-0.80.7-0.70.50.7
Patch foraging total patch changes 24 sec1.11.33.6-1.6-1.8-1.7-1.9-1.80.10.1-0.1-0.30.5-0.60.6-0.9-0.7
Patch foraging total patch changes 6 sec0.20.30.9-1.0-0.7-0.7-0.6-0.40.70.7-0.50.3-0.20.1-0.30.1-0.0
Patch foraging time to switch 0 sec2.94.69.5-2.30.3-0.20.30.82.92.9-3.12.7-2.52.3-2.31.62.1
Patch foraging water rate 0 sec3.04.811.32.90.51.10.40.2-3.1-3.13.4-2.82.4-2.22.1-1.1-1.8
Patch foraging water rate 12 sec6.19.322.24.71.01.40.9-0.1-4.2-4.24.1-3.63.1-2.93.0-1.8-3.0
Patch foraging water rate 18 sec2.23.08.62.90.91.31.00.5-2.3-2.32.4-2.01.6-1.31.4-0.5-1.8
Patch foraging water rate 24 sec2.83.99.43.10.81.10.70.2-2.7-2.72.8-2.41.9-1.81.8-1.0-2.0
Patch foraging water rate 6 sec3.85.511.73.40.50.90.5-0.2-3.2-3.23.2-2.82.5-2.22.3-1.3-2.6
Seeking ratio, delayed vs. immediate footshock0.60.71.50.00.60.90.90.90.70.7-0.60.8-0.80.9-0.91.21.2
Distance traveled before self-admin0.40.41.7-1.3-0.4-0.6-0.5-0.20.70.7-0.80.7-0.40.5-0.40.10.7
Distance traveled after self-admin0.20.20.7-0.9-0.4-0.6-0.4-0.10.60.6-0.40.3-0.40.1-0.3-0.20.5
Extensor digitorum longus weight2.28.530.0-5.5-3.7-4.3-3.5-3.13.13.1-2.81.9-1.31.1-0.8-1.00.3
Bone: elastic displacement2.93.36.71.9-0.40.1-0.4-0.8-2.4-2.42.6-2.22.1-2.02.0-1.4-2.1
Bone: elastic work1.52.03.2-0.0-1.5-1.3-1.4-1.8-1.1-1.11.6-1.51.4-1.41.4-1.6-1.8
Bone: endosteal estimation1.22.66.20.82.51.42.11.61.31.3-1.31.7-1.92.0-1.71.30.8
Bone: endosteal perimeter1.53.27.40.52.71.62.11.81.51.5-1.41.9-2.12.1-2.01.51.2
Epididymis fat weight1.02.46.82.12.62.52.42.4-0.3-0.30.30.2-0.70.7-0.81.40.7
Delta time in closed arm before/after self-admin0.60.62.50.9-0.4-0.1-0.3-0.7-0.7-0.70.8-0.90.8-0.80.7-0.4-1.6
Delta time in open arm before/after self-admin0.20.20.9-1.0-0.2-0.0-0.40.00.30.3-0.30.3-0.20.0-0.20.20.9
Diff in mean of infusions in LGA sessions0.20.30.9-0.7-0.90.0-1.0-0.80.10.10.3-0.40.2-0.50.10.2-0.4
Delay discount exponential model param0.60.72.6-0.3-0.6-1.5-0.8-0.7-0.4-0.40.7-0.60.6-0.70.8-1.6-0.6
Extinction: sum of active levers before priming2.52.56.9-2.6-1.0-1.2-0.9-0.52.22.2-2.11.7-1.51.2-1.30.51.3
Active lever presses in extinction session 61.31.23.8-1.9-1.7-1.5-2.0-1.70.10.1-0.1-0.30.5-0.60.6-0.9-0.6
Bone: final force0.91.55.5-2.4-1.2-1.7-1.4-1.31.41.4-1.20.8-0.70.6-0.5-0.30.2
Bone: final moment0.81.34.8-2.2-1.1-1.6-1.3-1.31.31.3-1.10.8-0.70.6-0.5-0.40.1
Food consumed during 24 hour testing period0.20.30.6-0.4-0.7-0.2-0.8-0.4-0.5-0.50.5-0.60.6-0.70.6-0.2-0.1
Glucose1.72.55.91.42.42.12.32.20.70.7-0.51.1-1.31.4-1.51.71.0
Heart weight1.31.96.22.52.02.32.01.7-1.0-1.00.8-0.30.10.1-0.11.1-0.1
Delay discount hyperbolic model param0.50.52.0-0.3-0.5-1.3-0.7-0.6-0.4-0.40.6-0.60.5-0.60.7-1.4-0.5
Intermittent access intake day 1-15 change0.40.41.10.40.00.2-0.2-0.0-1.0-1.01.0-0.90.7-0.80.7-0.5-0.3
Intermittent access intake escalation0.20.20.40.30.30.60.10.3-0.6-0.60.7-0.50.4-0.40.30.10.1
Intermittent access intake escalation 20.30.30.6-0.1-0.30.0-0.5-0.3-0.7-0.70.8-0.80.7-0.80.6-0.4-0.1
Intermitt. access day 1 inactive lever presses0.80.82.41.21.41.61.41.5-0.3-0.30.4-0.1-0.30.1-0.40.80.7
Intermitt. access day 15 inactive lever presses0.90.93.70.91.41.91.31.5-0.4-0.40.5-0.1-0.30.1-0.51.10.8
Intermitt. access escalation Index1.91.74.62.01.92.02.21.9-0.2-0.20.10.4-0.50.7-0.71.30.6
Intermittent access day 1 total infusions4.55.312.92.03.63.13.43.50.60.6-0.81.5-1.72.0-1.92.51.7
Intermittent access day 15 total infusions3.03.39.62.33.13.12.72.9-0.6-0.60.60.1-0.60.7-0.81.71.0
Intermittent access terminal intake (last 3 days)2.62.98.51.72.92.82.52.8-0.1-0.10.00.5-0.91.0-1.11.81.1
Intermittent access total infusions3.33.79.61.53.12.92.83.00.30.3-0.51.1-1.41.5-1.52.21.5
Intermittent access day 1 locomotion3.63.89.31.93.02.43.02.90.70.7-0.81.3-1.61.8-1.72.01.2
Intermittent access day 15 total locomotion2.12.36.21.62.52.52.32.5-0.2-0.20.20.3-0.70.7-0.91.51.1
Intermittent access total locomotion5.05.713.81.83.73.33.43.70.70.7-0.81.5-1.92.0-2.12.62.0
Intermittent access standard deviation0.40.51.00.80.60.90.40.5-1.0-1.00.9-0.70.6-0.50.50.0-0.2
Left kidney weight0.20.61.70.71.21.31.11.2-0.1-0.10.30.0-0.40.4-0.50.70.8
Right kidney weight0.00.10.2-0.30.20.50.00.3-0.1-0.10.4-0.2-0.1-0.1-0.10.10.5
Cocaine induced anxiety0.00.00.1-0.3-0.1-0.3-0.2-0.1-0.1-0.10.1-0.10.1-0.10.2-0.3-0.1
Post-drug Anxiety1.01.14.3-1.5-1.3-2.1-1.6-1.30.10.10.0-0.30.4-0.50.7-1.6-0.6
Baseline Anxiety1.11.23.1-1.4-1.7-1.8-1.7-1.60.30.3-0.1-0.30.4-0.50.5-1.1-0.8
Tail length1.54.57.0-0.6-2.6-2.2-2.5-2.6-1.6-1.61.8-2.02.2-2.22.3-2.4-2.1
Length with tail1.24.210.5-2.3-3.2-2.9-3.2-3.1-0.4-0.40.6-1.11.4-1.51.5-2.0-1.6
Length without tail0.71.64.8-2.2-2.0-1.8-2.2-1.90.50.5-0.4-0.10.4-0.40.4-0.8-0.8
Times rat made contact with spout0.10.10.3-0.4-0.5-0.4-0.3-0.40.30.3-0.40.3-0.10.1-0.10.10.2
Lifetime Intake3.23.69.01.63.02.82.82.90.40.4-0.61.1-1.41.6-1.62.21.4
Liver weight, left0.00.00.10.20.3-0.20.20.20.10.1-0.00.1-0.20.1-0.0-0.3-0.1
Liver weight, right0.20.41.70.80.2-0.20.0-0.2-0.6-0.60.6-0.70.5-0.40.6-0.6-1.3
Locomotor activity2.23.56.72.50.20.60.2-0.5-2.5-2.52.6-2.42.0-1.91.9-1.1-2.2
Locomotor testing distance3.35.610.83.30.20.40.2-1.0-3.1-3.13.1-2.82.5-2.42.5-1.7-2.9
Locomotor testing rearing2.03.18.32.90.60.60.6-0.4-2.3-2.32.4-2.01.7-1.61.7-1.1-2.0
Locomotion in novel chamber1.41.76.11.72.12.51.71.8-0.8-0.80.8-0.3-0.10.2-0.31.20.4
Locomotion in novel chamber post-restriction1.01.24.41.61.62.11.51.4-0.8-0.80.6-0.20.10.1-0.11.10.3
Fecal boli incidents, locomotor time 10.50.61.4-1.20.20.4-0.00.40.80.8-0.80.8-0.80.6-0.80.81.2
Change in fecal boli incidents, locomotor task0.20.21.20.80.2-0.10.3-0.1-0.2-0.20.2-0.20.20.00.2-0.1-1.1
Time >=10cm from walls, locomotor time 13.53.57.8-0.12.12.41.82.21.31.3-1.51.8-1.82.0-2.02.81.6
Bouts of movement, locomotor time 10.60.62.5-1.6-1.4-0.1-1.2-0.90.50.5-0.50.2-0.0-0.1-0.10.60.8
Total resting periods, locomotor time 10.50.62.4-1.5-1.00.1-0.9-0.50.60.6-0.70.5-0.20.2-0.40.81.0
Rest time, locomotor task time 10.60.71.41.20.51.00.30.2-1.2-1.21.1-0.90.8-0.70.60.1-0.8
Distance moved, locomotor task time 10.60.61.1-0.30.5-0.00.60.70.90.9-1.01.0-0.91.0-0.80.50.9
Vertical activity count, locomotor time 10.40.41.51.20.90.80.90.7-0.4-0.40.6-0.30.0-0.1-0.00.10.0
Time >=10cm from walls, locomotor time 20.30.31.1-0.80.20.20.20.40.40.4-0.70.7-0.40.6-0.40.51.1
Bouts of movement, locomotor time 20.30.30.9-1.0-0.6-0.1-0.5-0.20.60.6-0.60.5-0.30.2-0.40.50.8
Total resting periods, locomotor time 20.30.40.9-0.8-0.30.3-0.10.10.70.7-0.70.7-0.50.4-0.60.80.9
Rest time, locomotor task time 20.91.14.41.61.52.11.41.1-0.6-0.60.4-0.1-0.10.1-0.31.3-0.1
Distance moved, locomotor task time 20.60.73.0-1.1-1.2-1.7-1.1-1.00.00.0-0.2-0.10.4-0.20.6-1.3-0.0
Vertical activity count, locomotor time 22.32.64.90.8-1.1-1.5-1.1-1.5-1.5-1.51.8-1.91.7-1.71.8-2.2-1.9
Light reinforcement 10.20.30.60.7-0.10.1-0.1-0.2-0.8-0.80.5-0.70.7-0.80.6-0.2-0.4
Light reinforcement 20.30.31.30.20.81.10.51.1-0.2-0.2-0.20.2-0.10.1-0.30.80.6
Bone: marrow area1.22.76.50.92.51.52.21.51.31.3-1.31.8-1.92.0-1.81.30.8
Bone: maximum diameter0.10.31.2-1.1-0.1-0.6-0.6-0.60.50.5-0.60.5-0.40.3-0.2-0.30.0
Bone: maximum force2.03.58.7-2.9-0.5-1.2-0.7-0.52.72.7-2.42.1-2.01.9-1.80.81.2
Bone: maximum moment1.73.07.3-2.7-0.4-1.1-0.6-0.42.52.5-2.22.0-1.91.8-1.70.61.1
Mean time between licks in bursts1.21.63.90.3-1.2-1.5-1.1-2.0-0.9-0.91.0-1.01.3-1.11.4-1.6-1.8
Mean num. licks in bursts0.10.10.70.80.20.40.40.3-0.4-0.40.4-0.40.3-0.20.20.1-0.2
Cd content in liver0.40.41.00.70.51.00.30.8-0.9-0.90.6-0.70.6-0.60.40.30.0
Co content in liver2.12.54.92.0-0.40.3-0.1-0.3-2.2-2.22.0-1.91.9-1.91.8-1.0-1.3
Cu content in liver0.40.41.1-0.8-0.1-0.30.10.20.90.9-0.60.8-0.80.6-0.70.31.0
Fe content in liver0.10.10.4-0.4-0.3-0.4-0.5-0.6-0.1-0.10.2-0.10.2-0.10.2-0.3-0.5
K content in liver1.41.43.0-1.30.1-0.50.10.11.71.7-1.51.6-1.41.4-1.30.60.7
Mg content in liver2.42.54.1-0.51.10.51.21.21.91.9-1.71.9-2.02.0-1.91.31.6
Mn content in liver0.91.04.6-2.1-1.1-1.2-1.3-1.11.01.0-0.80.6-0.50.5-0.4-0.20.4
Na content in liver0.60.72.0-1.3-1.1-1.4-1.2-1.20.20.2-0.10.00.2-0.30.4-0.9-0.4
Rb content in liver1.01.23.21.31.71.51.81.60.40.4-0.20.6-0.90.9-0.91.00.9
Se content in liver0.50.71.0-0.80.60.60.30.60.80.8-0.80.9-0.91.0-0.91.01.0
Sr content in liver2.01.94.6-1.7-2.1-2.1-2.2-1.9-0.3-0.30.3-0.70.9-1.01.0-1.5-0.6
Zn content in liver0.60.61.8-1.3-0.6-0.5-0.40.11.21.2-0.80.8-0.80.6-0.80.30.9
Bone: minimum diameter2.13.96.40.52.51.52.31.91.91.9-1.72.2-2.42.4-2.31.71.7
Time in familiar zone, hab. session 10.30.30.70.30.80.50.80.40.40.4-0.50.7-0.60.7-0.60.30.4
Time in novel zone, hab. session 11.31.22.41.0-0.5-0.0-0.4-0.2-1.4-1.41.5-1.51.4-1.31.2-0.6-1.3
Total zone transitions, hab. session 10.30.41.4-1.2-0.5-0.3-0.3-0.10.90.9-0.70.7-0.70.6-0.60.40.8
Total locomotion distance, hab. session 10.71.02.30.31.11.21.21.50.70.7-0.70.8-0.91.0-1.01.30.8
Locomotion velocity, hab. session 10.50.71.1-0.10.70.70.81.00.80.8-0.80.9-0.90.9-0.90.90.8
Time in familiar zone, hab. session 21.61.73.71.0-0.6-0.9-0.6-1.2-1.3-1.31.5-1.31.4-1.31.5-1.6-1.9
Time in novel zone, hab. session 21.11.12.4-0.80.40.50.50.81.11.1-1.31.2-1.21.2-1.21.21.5
Total zone transitions, hab. session 21.72.24.6-1.20.3-0.20.40.42.12.1-2.01.8-1.82.0-1.71.21.2
Total locomotion distance, hab. session 21.31.82.70.11.20.91.31.41.41.4-1.51.4-1.51.6-1.51.50.9
Locomotion velocity, hab. session 21.72.33.20.11.51.21.51.71.51.5-1.61.5-1.71.8-1.71.81.1
Novel to familiar place preference ratio1.41.43.7-1.9-0.3-0.2-0.40.31.51.5-1.41.2-1.21.2-1.20.81.5
Novelty place preference1.11.12.4-1.5-0.00.0-0.10.41.31.3-1.31.2-1.21.1-1.10.81.5
Time in novel zone, NPP test0.80.81.7-1.2-0.00.1-0.10.41.11.1-1.01.0-1.00.9-1.00.71.3
Total zone transitions, NPP test1.01.43.6-1.9-0.7-1.0-0.6-0.51.61.6-1.51.1-1.11.2-1.00.40.8
Total locomotion distance, NPP test0.60.91.5-0.30.50.60.71.01.11.1-1.11.0-1.11.1-1.11.20.8
Locomotion velocity, NPP test0.71.01.5-0.50.50.60.70.91.21.2-1.21.1-1.11.1-1.21.21.0
Intraocular pressure0.30.40.90.40.20.6-0.2-0.1-1.0-1.00.8-0.70.7-0.70.6-0.2-0.2
Delta distance traveled before/after self-admin0.20.20.50.5-0.2-0.1-0.1-0.3-0.3-0.30.6-0.60.3-0.60.3-0.3-0.7
Delta ambulatory time before/after self-admin0.30.30.80.6-0.4-0.3-0.3-0.5-0.4-0.40.7-0.70.4-0.70.4-0.5-0.9
Parametrial fat weight2.04.08.81.43.02.42.92.81.11.1-0.71.5-1.81.9-2.02.01.7
Pavlov. Cond. lever latency0.20.30.80.7-0.10.2-0.00.1-0.9-0.90.3-0.50.8-0.80.7-0.2-0.4
Pavlov. Cond. magazine entry latency1.31.72.9-0.90.60.50.71.01.71.7-1.11.3-1.61.6-1.61.31.7
Pavlov. Cond. change in total contacts1.21.33.4-1.10.50.30.60.71.51.5-0.71.0-1.51.4-1.40.91.8
Pavlov. Cond. index score0.20.30.7-0.8-0.10.00.00.30.80.8-0.10.3-0.70.6-0.70.40.8
Pavlov. Cond. latency score0.20.30.6-0.50.20.10.20.30.80.8-0.10.3-0.70.7-0.70.50.7
Pavlov. Cond. lever contacts0.10.10.2-0.20.20.10.30.20.40.40.10.1-0.50.4-0.40.20.2
Pavlov. Cond. magazine entry number0.20.31.21.10.40.10.3-0.2-0.7-0.7-0.0-0.10.5-0.30.5-0.3-1.0
Pavlov. Cond. intertrial magazine entries0.20.20.70.40.20.80.20.4-0.7-0.70.8-0.60.4-0.50.30.20.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-1.1-0.1-0.1-0.10.31.01.0-0.30.5-0.90.8-0.80.51.0
Pavlov. Cond. response bias0.20.20.6-0.7-0.20.1-0.10.40.50.50.20.0-0.50.3-0.50.40.8
Pavlov. Cond. lever latency0.30.41.61.30.20.20.4-0.1-0.7-0.71.0-0.80.5-0.50.5-0.5-0.5
Pavlov. Cond. magazine entry latency1.61.85.6-2.4-1.1-1.3-1.0-0.61.71.7-1.81.6-1.10.9-0.90.21.1
Pavlov. Cond. change in total contacts2.12.97.6-2.8-0.4-0.3-0.50.42.02.0-2.42.2-1.61.5-1.61.22.2
Pavlov. Cond. index score1.51.96.2-2.5-0.7-0.8-0.8-0.21.71.7-1.91.7-1.21.1-1.10.61.3
Pavlov. Cond. latency score1.41.75.1-2.3-0.5-0.7-0.6-0.11.61.6-1.81.7-1.21.1-1.10.61.2
Pavlov. Cond. lever contacts0.20.21.4-1.2-0.7-0.5-0.9-0.30.10.1-0.50.30.1-0.10.1-0.00.0
Pavlov. Cond. magazine entry number2.73.311.63.41.61.81.61.1-2.2-2.22.2-2.01.3-1.11.1-0.1-1.5
Pavlov. Cond. intertrial magazine entries0.40.51.61.30.91.00.80.9-0.6-0.60.6-0.50.2-0.10.10.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.62.06.9-2.6-0.9-1.0-0.9-0.31.81.8-1.91.7-1.21.1-1.10.51.3
Pavlov. Cond. response bias0.71.04.4-2.1-1.0-0.9-1.1-0.41.01.0-1.41.0-0.50.4-0.40.10.7
Time in closed arm before self-admin0.30.30.6-0.70.3-0.20.10.40.50.5-0.70.7-0.60.6-0.50.10.8
Time in closed arm after self-admin0.10.10.20.40.30.40.40.30.10.10.00.0-0.20.2-0.30.4-0.3
Time in open arm before self-admin0.70.73.11.80.10.10.6-0.1-1.0-1.01.0-0.90.8-0.60.7-0.6-0.9
Time in open arm after self-admin0.50.61.00.6-0.4-0.3-0.3-0.4-1.0-1.00.9-0.90.9-1.01.0-0.9-0.4
Bone: periosteal estimation0.40.91.7-0.51.00.20.60.31.21.2-1.01.3-1.31.2-1.10.40.5
Bone: periosteal perimeter0.30.61.1-0.80.5-0.10.1-0.11.01.0-0.91.0-1.00.9-0.90.20.4
Bone: post-yield work10.414.121.2-2.22.51.42.32.74.64.6-4.54.5-4.64.5-4.53.54.0
Progressive ratio test 1 active lever presses0.91.02.61.51.61.61.41.5-0.8-0.80.6-0.20.00.0-0.10.60.4
Progressive ratio test 1 breakpoint0.80.82.21.51.41.31.21.2-0.9-0.90.7-0.40.2-0.20.10.30.2
Progressive ratio test 1 inactive lever presses0.60.62.01.21.11.41.21.1-0.4-0.40.3-0.0-0.10.1-0.30.80.4
Progressive ratio test 2 active lever presses1.51.64.81.52.22.01.92.1-0.5-0.50.50.0-0.30.4-0.51.00.8
Progressive ratio test 2 breakpoint1.51.74.32.02.12.11.81.9-1.1-1.11.1-0.60.2-0.10.00.60.4
Progressive ratio test 2 inactive lever presses3.23.610.22.33.23.12.93.1-0.6-0.60.50.2-0.70.7-0.91.61.5
Incentive Sensitization - Responses0.40.41.00.10.90.80.81.00.30.3-0.20.4-0.60.5-0.60.60.8
Incentive Sensitization - Breakpoint0.40.41.20.31.00.90.91.10.20.2-0.10.3-0.50.5-0.60.60.8
Sum of active levers in priming session hrs 5-61.31.24.2-2.0-1.7-1.1-2.1-1.5-0.1-0.10.3-0.60.6-0.90.7-0.7-0.3
Progressive ratio3.03.46.8-1.90.3-0.00.40.72.42.4-2.62.4-2.02.3-2.01.61.8
Food seeking constrained by brief footshock0.30.41.00.2-0.6-1.0-0.6-0.8-0.3-0.30.5-0.60.5-0.60.6-1.0-0.9
Seeking ratio, punishment vs. effort2.93.66.82.3-0.2-0.2-0.2-0.8-2.4-2.42.6-2.42.0-2.22.0-1.8-2.1
Retroperitoneal fat weight1.96.217.33.74.24.03.93.7-0.8-0.80.80.1-0.70.9-1.12.01.0
Reaction time number correct0.60.81.4-0.3-1.1-0.9-1.2-1.1-0.7-0.70.6-0.90.9-0.90.9-0.9-1.2
Reaction time mean minus median1.62.18.1-2.8-1.1-0.9-1.2-0.41.71.7-2.01.5-1.01.1-1.00.71.4
Reaction time mean minus median AUC0.60.83.9-2.0-1.2-0.9-1.2-0.70.60.6-1.00.5-0.20.2-0.10.00.5
Reaction time num false alarms0.60.91.81.3-0.2-0.10.1-0.6-1.2-1.21.0-1.01.1-1.01.0-0.6-1.3
Reaction time num false alarms AUC0.40.51.30.6-0.6-0.5-0.3-0.9-0.8-0.80.6-0.60.9-0.90.8-0.5-1.1
Reaction time trials correct on left0.60.81.4-0.3-1.1-0.9-1.2-1.1-0.7-0.70.6-0.90.9-0.90.9-0.9-1.2
Reaction time trials on left0.70.91.7-0.4-1.2-1.0-1.3-1.2-0.7-0.70.7-0.91.0-0.91.0-0.9-1.3
Reaction time mean0.30.41.6-0.9-0.00.20.00.50.60.6-0.70.7-0.50.6-0.60.61.3
Reaction time mean AUC0.50.72.4-1.00.20.40.20.70.80.8-0.90.9-0.70.8-0.80.91.5
Median of all reaction times0.30.41.6-0.40.40.50.40.80.50.5-0.60.7-0.50.6-0.60.71.3
Reaction time omissions0.40.62.7-1.6-1.1-0.6-0.9-0.50.70.7-0.90.6-0.30.3-0.30.30.7
Reaction time false alarm rate0.20.31.11.10.20.10.4-0.2-0.6-0.60.5-0.30.5-0.50.4-0.2-0.6
Reaction time premature initiation rate1.82.56.4-0.7-2.2-2.5-2.0-2.4-0.6-0.60.2-0.71.3-1.21.5-1.9-1.7
Reaction time premature initiations3.04.39.4-1.2-3.0-3.0-2.8-3.1-0.9-0.90.5-1.21.8-1.72.0-2.4-2.1
Std. dev. reaction times0.60.83.1-1.8-0.7-0.3-0.7-0.00.90.9-1.20.9-0.60.7-0.60.61.2
Reaction time trials completed0.70.91.7-0.4-1.2-1.0-1.3-1.2-0.7-0.70.7-0.91.0-0.91.0-0.9-1.3
Reaction time trials AUC0.50.81.6-0.2-1.0-0.8-1.1-1.0-0.7-0.70.7-0.90.9-0.91.0-0.8-1.3
Run reversals in cocaine runway, females1.11.12.0-0.10.50.30.90.61.31.3-1.41.4-1.31.4-1.21.10.5
Run reversals in cocaine runway, males2.22.13.20.8-0.7-0.6-0.8-0.9-1.8-1.81.8-1.81.7-1.71.7-1.6-1.6
Latency to leave start box in cocaine runway1.21.31.8-0.21.00.81.01.11.21.2-1.11.2-1.31.3-1.31.21.2
Latency to leave start box in cocaine runway, F0.70.72.0-0.40.50.30.70.80.90.9-1.01.0-1.00.9-0.90.71.4
Latency to leave start box in cocaine runway, M0.10.10.20.10.40.30.30.30.50.5-0.20.2-0.50.3-0.50.4-0.2
Std. dev. time between licks in bursts1.61.93.91.2-0.6-0.9-0.5-1.4-1.5-1.51.5-1.51.5-1.31.6-1.6-2.0
Total sessions with >9 infusions1.31.43.81.42.01.61.91.80.20.2-0.20.6-0.80.9-0.91.20.3
Short access day 1 total inactive lever presses1.51.64.31.92.02.02.12.0-0.3-0.30.50.0-0.50.4-0.61.00.6
Short access day 10 total inactive lever presses1.21.35.62.41.41.41.61.2-1.1-1.11.2-0.80.4-0.50.30.1-0.2
Short access day 1 total infusions3.33.57.31.52.72.52.72.70.70.7-0.81.3-1.51.7-1.72.21.5
Short access day 10 total infusions4.85.38.60.72.92.72.82.91.61.6-1.72.1-2.32.4-2.52.91.9
Short access total infusions2.22.55.01.12.22.02.22.20.80.8-0.91.3-1.41.6-1.51.91.0
Short access day 1 locomotion2.22.35.71.62.42.02.42.30.50.5-0.50.9-1.21.4-1.31.50.9
Short access day 10 total locomotion2.02.25.01.22.21.82.22.20.60.6-0.81.1-1.31.5-1.41.61.2
Short access total locomotion1.81.94.41.12.01.52.12.00.60.6-0.71.1-1.21.4-1.21.31.0
One hour access (0.3 mA shock)3.23.79.63.13.03.12.72.7-1.6-1.61.4-0.70.3-0.00.01.10.3
Compulsive drug intake1.91.94.7-0.7-2.2-2.0-1.9-2.2-0.4-0.40.4-0.81.1-1.21.2-1.6-1.3
One hour access (shock baseline)2.93.410.32.23.13.22.73.0-0.9-0.90.8-0.1-0.40.5-0.61.61.2
Social response proportion0.40.41.3-1.1-0.6-0.8-0.8-0.90.60.6-0.70.6-0.30.3-0.2-0.20.2
Social responses0.40.51.2-0.2-0.8-0.8-0.9-1.1-0.4-0.40.6-0.70.7-0.70.7-0.8-0.9
Social time0.71.02.0-0.2-1.0-1.3-1.1-1.4-0.5-0.50.7-0.80.8-0.81.0-1.4-1.2
Soleus weight1.13.211.53.42.72.72.72.0-1.4-1.41.6-0.80.3-0.10.00.8-0.1
Bone: stiffness2.23.57.6-2.8-0.3-0.9-0.4-0.02.72.7-2.42.2-2.11.9-1.91.01.7
Tibialis anterior weight3.411.635.9-6.0-5.3-5.5-5.4-4.71.71.7-1.50.30.4-0.60.8-2.5-1.2
Time to tail flick, vehicle, before self-admin0.60.61.4-0.90.10.50.00.10.80.8-1.11.0-0.61.0-0.81.20.5
Time to tail flick, vehicle, after self-admin0.40.41.2-0.7-0.2-0.5-0.1-0.41.01.0-1.10.9-0.60.8-0.60.4-0.1
Time to tail flick, test, before self-admin1.31.32.91.11.61.61.71.40.40.4-0.70.9-0.81.2-0.91.50.5
Time to tail flick, test, after self-admin0.10.10.20.0-0.3-0.0-0.4-0.5-0.4-0.40.3-0.40.4-0.30.4-0.1-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.2-0.2-0.5-0.1-0.30.60.6-0.50.4-0.30.2-0.3-0.1-0.2
Delta time to tail flick, test, before/after SA2.92.65.2-1.1-2.2-1.8-2.3-2.1-1.0-1.01.1-1.41.5-1.71.6-1.9-1.0
Tibia length0.51.47.7-2.8-1.4-1.4-1.8-1.30.90.9-0.70.6-0.30.1-0.2-0.50.4
Ambulatory time before self-admin0.50.51.9-1.4-0.2-0.1-0.40.10.90.9-0.90.8-0.70.6-0.70.60.9
Ambulatory time after self-admin0.80.91.8-0.50.70.60.61.01.11.1-0.80.9-1.20.9-1.20.91.3
Bone: tissue strength0.20.20.5-0.50.10.40.10.20.50.5-0.70.4-0.40.5-0.50.70.6
Total heroin consumption1.92.37.7-2.8-2.0-2.4-1.9-1.71.41.4-1.40.9-0.50.3-0.2-0.80.4
Bone: trabecular number1.52.33.7-1.40.70.40.51.31.91.9-1.71.7-1.81.6-1.91.61.6
Bone: trabecular spacing0.30.41.01.0-0.10.10.1-0.3-0.9-0.90.6-0.70.8-0.70.8-0.4-0.8
Bone: trabecular thickness1.01.12.00.41.41.21.31.40.80.8-0.50.9-1.11.0-1.21.21.1
Bone: trabecular tissue density0.81.23.92.01.41.71.30.9-1.3-1.31.1-0.60.5-0.40.40.2-0.1
Water consumed over 24 hours0.40.51.4-0.7-1.2-1.0-1.1-1.0-0.1-0.10.2-0.50.5-0.50.5-0.6-0.1
Number of responses in last shaping day0.80.82.21.50.50.30.50.2-1.3-1.31.2-1.00.9-0.80.9-0.7-0.7