Hub : Genes

Snx16

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr2_91354845_91356529 0.14 0.08 9.0e-06 0.14 0.12 0.13 0.13 2.0e-06 1.1e-05 3.1e-06 3.1e-06
2 PL intron excision ratio chr2_91354845_91356529 0.13 0.08 2.7e-11 0.08 0.07 0.08 0.08 3.1e-09 1.5e-08 4.5e-09 5.5e-09
3 Adipose alternative TSS XM_039103035.1 0.03 0.03 2.2e-03 0.01 0.01 0.01 0.01 7.5e-03 3.8e-02 4.2e-02 6.4e-02
4 Brain isoform ratio NM_022289.3 0.05 0.04 2.0e-03 0.01 0.02 0.01 0.01 4.0e-02 9.2e-03 7.5e-02 4.5e-02
5 NAcc intron excision ratio chr2_91354845_91356529 0.06 0.04 3.6e-05 0.02 0.02 0.02 0.01 1.6e-03 2.1e-03 4.8e-03 1.4e-02
6 PL isoform ratio XM_006232135.4 0.03 0.02 5.1e-03 0.01 0.01 0.01 0.01 3.1e-02 3.0e-02 2.8e-02 7.2e-02
7 NAcc isoform ratio XM_006232135.4 0.04 0.03 1.3e-03 0.01 0.02 0.01 0.01 3.8e-02 2.6e-03 1.2e-02 1.8e-02
8 Brain intron excision ratio chr2_91354845_91356529 0.13 0.08 2.2e-08 0.04 0.06 0.05 0.05 2.4e-04 1.8e-06 2.0e-05 1.5e-05
9 Brain intron excision ratio chr2_91355443_91356529 0.04 0.03 9.0e-03 -0 0.01 0 0 4.5e-01 4.1e-02 1.2e-01 3.3e-01
10 BLA isoform ratio XM_006232135.4 0.09 0.07 1.3e-03 0.03 0 0.01 0.02 6.0e-03 1.7e-01 9.9e-02 2.5e-02
11 Adipose intron excision ratio chr2_91354845_91356529 0.04 0.03 9.4e-04 0.01 0.02 0.01 0.02 2.6e-02 2.2e-03 1.9e-02 2.6e-03
12 Adipose isoform ratio XM_006232135.4 0.03 0.02 5.6e-03 0.01 0.02 0.01 0.01 6.9e-02 3.9e-03 8.2e-03 1.1e-02
13 BLA intron excision ratio chr2_91354845_91356529 0.12 0.09 4.5e-04 0.06 0.02 0.04 -0 3.6e-04 2.1e-02 4.2e-03 4.5e-01
14 Brain isoform ratio XM_006232135.4 0.09 0.06 6.2e-06 0.02 0.05 0.05 0.04 8.3e-03 8.9e-06 3.1e-05 7.9e-05
15 pVTA intron excision ratio chr2_91355443_91356529 0.1 0.08 1.2e-03 0.08 0.07 0.06 0.08 3.2e-04 6.2e-04 1.2e-03 2.8e-04
16 Adipose gene expression Snx16 0.14 0.09 9.5e-11 0.07 0.07 0.06 0.06 2.1e-08 8.5e-08 1.9e-07 9.2e-08
17 NAcc gene expression Snx16 0.23 0.1 0.0e+00 0.17 0.21 0.2 0.2 1.1e-19 1.3e-23 4.1e-23 2.6e-23
18 IL gene expression Snx16 0.32 0.19 4.4e-03 0.07 -0 0.07 0.08 7.2e-03 3.4e-01 9.2e-03 4.7e-03
19 Brain gene expression Snx16 0.29 0.11 0.0e+00 0.2 0.21 0.22 0.22 2.2e-18 3.9e-19 8.0e-20 6.7e-20
20 LHb gene expression Snx16 0.26 0.16 5.1e-03 0.02 0.02 0.04 0.02 1.0e-01 1.3e-01 3.3e-02 1.2e-01
21 pVTA gene expression Snx16 0.38 0.15 2.2e-12 0.27 0.26 0.25 0.27 4.0e-12 1.2e-11 3.5e-11 3.6e-12
22 OFC gene expression Snx16 0.29 0.14 2.1e-03 0.04 0.03 0.02 0.03 4.6e-02 6.7e-02 1.1e-01 6.5e-02
23 PL gene expression Snx16 0.3 0.13 0.0e+00 0.2 0.21 0.21 0.21 1.8e-21 9.6e-23 1.6e-22 2.5e-22
24 BLA gene expression Snx16 0.23 0.15 3.7e-07 0.1 0.08 0.12 0.09 5.5e-06 3.8e-05 5.1e-07 9.6e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.91.55.2-1.4-1.71.6-1.1-1.6-0.90.90.8-0.7-2.30.60.6-2.20.5-2.01.7-0.4-0.3-0.80.5-0.60.8-0.71.6
Area under the delay curve0.80.83.31.21.1-1.10.81.30.7-0.7-0.60.61.7-0.5-0.51.8-0.41.3-1.20.20.30.4-0.50.4-0.10.4-0.8
BMI with tail1.65.39.72.72.7-2.62.82.93.1-2.8-2.82.80.6-2.8-2.80.8-2.71.2-1.3-2.2-2.4-1.42.1-2.12.0-1.90.7
BMI without tail3.16.513.73.23.6-3.63.33.73.0-3.1-3.03.01.6-3.0-3.01.8-2.92.3-2.2-2.0-1.8-0.91.4-1.81.0-1.5-0.2
Body weight0.83.26.81.91.8-1.82.01.72.6-2.0-2.12.10.0-2.1-2.10.3-2.10.5-0.2-2.1-2.3-1.52.1-1.71.7-1.71.0
Weight adjusted by age0.20.30.70.10.4-0.50.50.70.1-0.6-0.50.5-0.3-0.5-0.5-0.3-0.5-0.0-0.4-0.3-0.6-0.70.7-0.70.9-0.40.6
Bone surface2.24.013.2-2.0-2.02.0-1.0-2.0-0.70.70.5-0.3-3.60.30.2-3.6-0.0-3.13.1-1.5-1.6-1.81.8-1.71.9-2.02.9
Bone volume2.23.712.8-1.9-2.01.9-0.9-1.9-0.70.60.5-0.3-3.60.20.1-3.5-0.1-3.12.8-1.4-1.5-1.91.7-1.72.0-2.02.9
Breakpoint value in progressive ratio session1.11.22.01.31.3-1.31.41.41.2-1.4-1.41.31.0-1.3-1.31.1-1.20.9-0.9-0.8-0.7-0.70.6-0.80.6-0.60.2
Number of licking bursts0.40.52.4-0.9-0.70.8-0.5-0.7-0.40.40.4-0.4-1.60.30.3-1.50.2-0.90.9-0.2-0.3-0.20.6-0.30.3-0.40.4
Context. condit. distance diff. score0.20.30.70.20.2-0.1-0.1-0.1-0.10.20.2-0.30.70.30.30.60.40.7-0.40.50.80.7-0.80.7-0.70.8-0.8
Locomotion velocity, session 11.61.73.81.91.7-1.81.71.71.7-1.6-1.51.51.4-1.5-1.41.3-1.41.4-1.3-0.8-0.7-0.20.4-0.50.5-0.4-0.2
Locomotion distance, session 11.41.82.81.41.2-1.31.51.31.6-1.5-1.61.60.6-1.6-1.60.5-1.60.4-0.3-1.5-1.7-1.41.5-1.41.1-1.20.8
Locomotion velocity, session 21.41.73.41.71.6-1.71.71.81.6-1.6-1.61.51.1-1.5-1.51.0-1.41.2-1.3-0.9-0.8-0.80.7-0.70.6-0.6-0.1
Locomotion distance, session 22.12.94.91.51.3-1.41.91.52.0-2.0-2.02.00.1-2.0-2.10.1-2.10.1-0.2-2.0-2.2-1.82.1-2.01.7-1.91.4
Locomotion velocity, session 30.10.10.40.1-0.0-0.1-0.1-0.0-0.10.10.1-0.10.50.10.10.40.20.2-0.20.30.60.3-0.60.3-0.30.4-0.4
Locomotion distance, session 30.20.20.7-0.4-0.40.4-0.1-0.40.0-0.0-0.10.1-0.3-0.1-0.1-0.4-0.2-0.80.8-0.5-0.3-0.30.4-0.60.7-0.60.7
Stereotopy head waving bouts, day 30.70.81.80.30.3-0.40.80.30.8-0.9-0.90.9-0.5-1.0-1.0-0.5-1.0-0.50.4-1.2-1.0-1.41.2-1.11.3-1.21.2
Stereotopy head waving duration, day 30.40.50.90.90.8-0.80.90.80.9-0.9-0.90.90.6-0.9-0.90.5-0.90.5-0.5-0.6-0.4-0.80.5-0.40.5-0.50.3
Locomotion velocity, session 73.53.811.2-1.9-2.22.2-1.0-2.1-0.50.60.4-0.2-2.90.20.1-2.8-0.1-3.33.3-1.6-1.8-2.12.0-1.82.0-2.02.9
Locomotion distance, session 72.22.86.4-2.2-2.42.4-1.8-2.4-1.51.61.5-1.3-2.51.31.2-2.41.1-2.52.5-0.1-0.5-0.50.7-0.30.4-0.51.3
Stereotopy head waving bouts, day 70.70.81.30.80.9-0.91.10.91.1-1.1-1.11.10.7-1.1-1.10.6-1.10.2-0.2-0.9-0.7-0.70.6-0.81.0-0.90.7
Stereotopy head waving duration, day 70.70.82.01.11.3-1.31.11.21.0-1.0-1.00.91.4-0.9-0.91.4-0.81.1-1.0-0.30.00.1-0.2-0.10.2-0.1-0.3
Locomotion velocity, session 82.12.55.92.32.4-2.42.02.11.8-1.8-1.81.61.7-1.6-1.61.8-1.52.1-2.0-0.6-0.1-0.10.0-0.30.2-0.1-0.7
Locomotion distance, session 80.91.32.21.51.5-1.51.41.21.4-1.4-1.41.41.1-1.3-1.31.0-1.31.0-0.7-0.9-0.9-0.60.8-0.80.5-0.60.0
Degree of sensitization distance0.30.31.8-0.6-0.70.7-0.5-0.7-0.50.50.5-0.5-1.40.40.4-1.20.4-0.60.60.0-0.3-0.50.40.00.0-0.10.4
Degree of sensitization stereotypy1.11.22.41.41.5-1.51.41.51.3-1.3-1.21.21.4-1.2-1.21.4-1.11.2-1.1-0.5-0.3-0.10.1-0.30.5-0.3-0.1
Conditioned locomotion0.10.20.30.50.4-0.50.50.50.5-0.5-0.50.50.4-0.5-0.50.3-0.50.4-0.3-0.3-0.4-0.50.3-0.20.2-0.20.1
Cocaine response after cond. corrected0.70.71.3-1.1-1.11.0-1.1-1.0-1.11.11.1-1.0-1.01.01.0-0.91.0-0.60.70.60.60.5-0.50.6-0.50.4-0.1
Cocaine response after cond. not corrected1.11.22.2-1.5-1.41.3-1.4-1.4-1.51.41.4-1.3-1.31.31.3-1.21.2-1.01.00.80.60.6-0.40.6-0.50.4-0.0
Cocaine response before conditioning0.20.20.7-0.6-0.40.5-0.3-0.4-0.30.20.2-0.1-0.60.10.1-0.70.0-0.80.6-0.2-0.3-0.40.6-0.30.5-0.50.6
Saline control response1.21.63.9-0.9-1.11.1-0.3-1.0-0.00.1-0.10.2-1.9-0.2-0.3-1.7-0.4-2.01.9-1.2-1.3-1.71.5-1.41.6-1.42.0
Bone: connectivity density1.01.54.1-1.5-1.71.7-1.3-1.8-1.01.11.0-0.9-2.00.90.9-2.00.8-1.81.8-0.1-0.1-0.40.2-0.20.4-0.31.2
Bone: cortical apparent density0.60.72.11.31.1-0.90.81.00.9-0.7-0.70.61.5-0.6-0.51.4-0.51.4-1.20.10.50.3-0.60.4-0.10.6-0.8
Bone: cortical area0.71.03.0-0.2-0.20.20.40.10.5-0.6-0.60.7-1.4-0.7-0.8-1.2-0.9-1.10.7-1.2-0.9-1.71.1-1.41.4-1.51.7
Bone: cortical porosity0.30.31.2-0.10.0-0.00.30.10.4-0.4-0.40.5-0.6-0.5-0.5-0.5-0.6-0.60.4-0.7-0.6-1.10.7-0.80.8-0.91.0
Bone: cortical porosity0.30.31.00.10.2-0.20.50.40.5-0.6-0.60.6-0.3-0.6-0.6-0.2-0.7-0.40.1-0.7-0.7-1.00.7-0.70.7-0.80.8
Bone: cortical thickness0.81.34.00.60.5-0.51.10.71.1-1.2-1.21.2-0.6-1.3-1.3-0.5-1.3-0.40.1-1.4-0.9-2.01.1-1.41.6-1.41.5
Bone: cortical thickness1.92.34.91.92.0-2.01.92.21.7-2.0-1.81.70.4-1.8-1.70.7-1.71.4-1.8-0.9-0.1-1.70.3-0.81.0-0.80.5
Bone: cortical tissue density0.60.82.31.31.1-0.90.81.00.9-0.7-0.70.61.5-0.6-0.51.5-0.41.4-1.20.20.60.4-0.70.4-0.10.6-0.8
Condit. Reinf. active minus inactive responses6.16.910.82.32.4-2.53.12.63.1-3.2-3.23.20.3-3.3-3.30.3-3.30.4-0.6-3.0-2.6-2.52.4-2.83.0-2.82.1
Condit. Reinf. active-inactive response ratio7.58.112.82.62.8-2.83.42.83.6-3.5-3.53.50.3-3.6-3.60.3-3.60.7-0.8-3.2-2.8-2.52.5-3.03.1-2.92.1
Condit. Reinf. active responses5.66.810.52.02.2-2.32.92.53.0-3.1-3.13.20.2-3.2-3.20.2-3.20.1-0.3-3.1-2.8-2.82.7-2.93.1-2.92.4
Condit. Reinf. inactive responses0.20.20.60.20.2-0.30.40.40.3-0.5-0.50.50.5-0.5-0.50.6-0.5-0.20.0-0.4-0.5-0.80.5-0.40.4-0.50.4
Incentive salience index mean6.57.912.32.52.6-2.63.32.73.4-3.4-3.43.50.4-3.5-3.50.4-3.50.5-0.6-3.2-2.9-2.92.6-3.03.2-2.92.3
Condit. Reinf. lever presses2.63.45.41.91.9-1.82.21.72.3-2.3-2.32.30.6-2.3-2.30.7-2.30.6-0.6-2.0-1.8-1.91.6-1.91.9-1.61.3
Condit. Reinf. active minus inactive responses2.63.28.8-1.6-1.51.7-0.6-1.5-0.30.20.10.1-3.0-0.2-0.2-2.9-0.4-2.82.7-1.6-1.7-2.21.9-1.92.0-2.12.9
Condit. Reinf. active-inactive response ratio1.81.95.1-1.1-0.91.0-0.2-0.90.0-0.1-0.20.3-2.3-0.4-0.4-2.2-0.6-2.12.0-1.5-1.5-1.71.6-1.71.7-1.82.3
Condit. Reinf. active responses3.04.210.8-2.0-2.02.1-0.8-1.9-0.60.40.3-0.1-3.30.0-0.1-3.2-0.3-3.33.1-1.7-1.8-2.62.1-2.02.1-2.33.2
Condit. Reinf. inactive responses0.30.41.9-0.5-0.60.5-0.2-0.6-0.10.0-0.00.1-0.6-0.1-0.1-0.6-0.2-0.90.8-0.5-0.5-1.40.7-0.50.7-0.61.1
Condit. Reinf. lever presses1.41.94.8-1.2-1.31.2-0.4-1.2-0.10.10.00.1-2.0-0.1-0.2-2.0-0.4-2.22.0-1.2-1.5-2.01.8-1.41.5-1.62.2
Condit. Reinf. lever reinforcers received3.14.311.5-2.2-2.12.2-1.0-2.0-0.70.50.4-0.2-3.40.10.1-3.3-0.2-3.43.1-1.6-1.7-2.62.0-1.92.0-2.23.2
Conditioned reinforcement - actives1.81.85.4-1.6-2.22.2-1.5-1.9-0.81.41.2-1.0-1.61.11.0-1.70.9-2.22.3-0.1-0.0-0.20.2-0.20.2-0.40.9
Conditioned reinforcement - inactives0.00.10.2-0.3-0.10.5-0.1-0.1-0.20.00.0-0.00.00.00.0-0.10.0-0.30.4-0.1-0.2-0.30.30.20.2-0.20.5
Conditioned locomotion1.11.34.8-1.1-1.81.8-1.1-1.6-0.41.00.8-0.7-1.70.70.7-1.80.5-1.92.2-0.4-0.2-0.40.4-0.20.5-0.51.0
Patch foraging indifference point 0 sec0.91.42.3-1.1-1.11.2-1.4-1.1-1.41.51.5-1.5-0.71.51.5-0.61.5-0.40.21.31.40.9-1.31.2-1.21.1-0.7
Patch foraging indifference point AUC0.30.31.70.70.7-1.00.40.70.0-0.4-0.20.20.2-0.2-0.20.3-0.11.0-1.30.40.50.3-0.40.4-0.10.4-0.4
Delay disc. indifference point, 0s delay0.10.10.20.2-0.30.2-0.3-0.2-0.20.40.4-0.40.00.40.40.20.40.10.00.40.40.4-0.40.4-0.40.5-0.4
Delay disc. indifference point, 16s delay0.90.94.41.01.1-1.10.81.10.7-0.6-0.60.52.1-0.5-0.52.1-0.31.4-1.30.30.40.5-0.60.5-0.30.5-1.0
Delay disc. indifference point, 2s delay1.41.62.81.10.8-0.81.30.91.5-1.3-1.41.5-0.0-1.5-1.50.1-1.5-0.20.2-1.6-1.6-1.51.5-1.21.7-1.51.2
Delay disc. indifference point, 24s delay0.20.21.00.00.3-0.30.00.4-0.10.00.1-0.10.90.10.21.00.20.6-0.50.50.50.5-0.60.8-0.10.5-0.6
Delay disc. indifference point, 4s delay1.11.23.11.51.5-1.51.11.70.8-1.0-0.90.81.8-0.8-0.71.7-0.61.7-1.60.20.40.3-0.50.4-0.20.4-1.0
Delay disc. indifference point, 8s delay0.60.61.70.20.2-0.2-0.20.6-0.50.30.4-0.51.30.50.51.30.60.8-0.91.11.01.0-1.11.0-0.91.0-1.1
Indifference point function ln k0.10.10.80.40.3-0.10.10.00.30.0-0.10.00.90.00.00.70.00.5-0.00.1-0.10.5-0.10.2-0.60.4-0.8
Indifference point function log k0.10.10.80.40.3-0.10.10.00.30.0-0.10.00.90.00.00.70.00.5-0.00.1-0.10.5-0.10.2-0.60.4-0.8
Patch foraging total patch changes 0 sec0.81.32.8-0.7-0.80.8-1.2-0.7-1.21.31.4-1.4-0.31.41.4-0.21.40.1-0.31.51.71.1-1.51.4-1.41.3-1.0
Patch foraging total patch changes 12 sec0.81.12.1-0.6-0.60.6-1.1-0.7-1.41.11.2-1.3-1.01.21.2-0.81.20.2-0.41.31.40.9-1.21.3-1.11.2-0.6
Patch foraging total patch changes 18 sec0.40.52.50.70.8-1.00.41.10.1-0.4-0.20.10.7-0.2-0.10.9-0.11.0-1.60.71.00.3-0.80.8-0.40.5-0.6
Patch foraging total patch changes 24 sec0.60.71.70.2-0.10.1-0.6-0.3-0.50.70.8-0.80.30.80.90.50.90.6-0.71.21.31.1-1.21.3-1.21.3-1.2
Patch foraging total patch changes 6 sec0.40.62.30.10.2-0.2-0.30.0-0.50.40.5-0.6-0.10.60.60.10.70.8-1.11.11.50.8-1.30.9-0.91.0-0.7
Patch foraging time to switch 0 sec2.23.35.21.41.6-1.42.11.62.1-2.2-2.32.30.9-2.3-2.30.9-2.30.00.1-2.2-1.6-2.21.6-2.21.9-2.01.5
Patch foraging water rate 0 sec0.61.02.3-0.4-0.30.2-0.8-0.4-1.10.91.1-1.1-0.41.11.1-0.41.20.7-0.81.41.11.4-1.01.5-1.31.4-1.1
Patch foraging water rate 12 sec1.11.62.7-1.6-1.61.4-1.6-1.5-1.21.61.6-1.6-0.71.61.6-0.81.5-0.90.81.20.81.1-0.81.2-1.10.8-0.4
Patch foraging water rate 18 sec0.40.51.8-0.9-0.90.9-0.9-1.0-0.40.80.8-0.8-1.30.80.8-1.30.7-0.60.70.30.10.2-0.00.3-0.40.20.1
Patch foraging water rate 24 sec0.81.13.4-0.2-0.20.2-0.7-0.3-0.60.90.9-0.90.61.01.00.71.10.9-0.71.31.01.8-1.21.6-1.71.4-1.6
Patch foraging water rate 6 sec1.31.93.6-1.8-1.91.8-1.8-1.7-1.51.71.7-1.6-1.21.61.6-1.11.6-1.31.21.00.70.6-0.61.1-0.70.70.0
Seeking ratio, delayed vs. immediate footshock5.46.211.6-3.3-3.33.4-3.2-3.2-3.33.03.0-2.9-2.52.82.8-2.62.7-2.52.31.61.01.0-0.71.5-0.61.00.4
Distance traveled before self-admin0.20.20.80.2-0.30.4-0.3-0.5-0.20.40.3-0.30.70.30.40.90.40.10.00.40.30.3-0.40.5-0.50.5-0.3
Distance traveled after self-admin0.60.61.4-0.3-0.10.3-0.6-0.3-0.30.70.7-0.80.70.80.80.50.90.6-0.51.11.11.1-1.11.2-1.21.0-1.0
Extensor digitorum longus weight6.626.249.97.16.9-6.96.66.36.4-6.3-6.26.04.6-6.0-5.94.6-5.65.0-4.4-3.6-3.2-2.52.6-2.92.5-2.1-0.3
Bone: elastic displacement0.91.02.20.20.2-0.10.70.30.9-0.8-0.91.0-0.4-1.0-1.0-0.4-1.0-0.80.8-1.4-1.5-1.21.3-1.51.4-1.51.4
Bone: elastic work0.81.12.5-0.1-0.00.10.50.10.7-0.7-0.70.8-0.9-0.9-0.9-0.8-1.0-1.11.0-1.4-1.4-1.51.4-1.61.4-1.61.6
Bone: endosteal estimation1.22.66.3-0.9-0.90.9-0.1-0.90.2-0.2-0.30.5-2.5-0.5-0.6-2.4-0.7-2.22.3-1.9-2.4-1.72.4-2.01.8-2.22.3
Bone: endosteal perimeter0.40.82.8-1.1-1.11.1-0.7-1.0-0.60.60.5-0.4-1.60.40.3-1.70.3-1.51.5-0.5-0.8-0.30.7-0.60.4-0.81.0
Epididymis fat weight0.51.13.20.4-0.00.0-0.4-0.0-0.30.70.7-0.71.30.80.81.30.91.1-0.91.30.81.8-1.31.4-1.41.6-1.7
Delta time in closed arm before/after self-admin0.30.30.6-0.1-0.50.5-0.5-0.5-0.10.70.6-0.60.30.60.70.30.70.20.00.60.80.7-0.80.6-0.70.7-0.7
Delta time in open arm before/after self-admin0.10.10.5-0.20.1-0.1-0.20.0-0.70.10.2-0.2-0.20.20.20.10.2-0.0-0.20.20.30.3-0.30.1-0.40.1-0.2
Diff in mean of infusions in LGA sessions2.02.24.11.51.6-1.61.81.72.0-1.8-1.81.80.2-1.8-1.80.2-1.80.5-0.5-1.6-1.5-1.41.4-1.51.3-1.50.8
Delay discount exponential model param0.60.62.5-1.0-1.01.0-0.7-1.2-0.60.60.6-0.5-1.50.50.4-1.60.4-1.11.0-0.2-0.2-0.30.4-0.40.0-0.30.6
Extinction: sum of active levers before priming0.60.61.40.91.0-1.11.01.20.9-1.0-0.90.80.1-0.9-0.90.1-0.80.8-1.0-0.4-0.6-0.60.6-0.30.6-0.30.2
Active lever presses in extinction session 60.20.20.6-0.5-0.70.6-0.5-0.6-0.80.50.5-0.5-0.10.50.5-0.30.4-0.60.50.20.20.2-0.20.1-0.40.1-0.0
Bone: final force0.61.02.5-0.10.1-0.10.60.20.7-0.7-0.70.8-1.3-0.9-0.9-1.1-1.0-0.90.7-1.4-1.1-1.31.1-1.51.3-1.61.4
Bone: final moment0.60.92.4-0.4-0.30.30.2-0.30.4-0.4-0.40.5-1.6-0.5-0.6-1.4-0.7-1.21.0-1.2-1.0-1.31.1-1.31.2-1.41.4
Food consumed during 24 hour testing period1.31.52.71.41.6-1.71.61.51.5-1.6-1.61.50.7-1.6-1.50.7-1.51.0-1.0-1.1-0.7-0.90.6-1.00.8-0.80.2
Glucose0.91.32.91.31.7-1.61.51.71.3-1.5-1.41.40.7-1.4-1.40.7-1.31.0-1.1-0.8-0.5-0.60.5-0.70.8-0.70.2
Heart weight1.21.73.7-1.4-1.61.7-1.7-1.9-1.11.71.6-1.6-0.31.61.6-0.21.6-0.80.91.10.81.0-0.80.9-1.01.2-0.7
Delay discount hyperbolic model param0.70.82.7-1.3-1.11.2-0.9-1.4-0.80.80.7-0.7-1.60.70.6-1.60.6-1.21.2-0.0-0.1-0.20.3-0.2-0.1-0.20.6
Intermittent access intake day 1-15 change4.14.06.4-2.3-2.52.3-2.5-2.3-2.52.52.5-2.5-1.22.52.5-1.32.4-1.11.11.81.71.6-1.51.7-1.61.5-0.7
Intermittent access intake escalation3.13.04.9-2.1-2.22.0-2.2-2.0-2.22.22.2-2.2-1.22.12.1-1.32.1-1.11.11.51.41.3-1.21.5-1.31.2-0.5
Intermittent access intake escalation 23.73.66.8-2.6-2.52.5-2.5-2.3-2.62.32.3-2.2-1.92.22.2-2.02.1-1.81.61.30.90.8-0.71.2-0.80.80.2
Intermitt. access day 1 inactive lever presses1.92.07.01.01.1-0.90.41.00.3-0.1-0.1-0.12.60.20.22.50.32.1-1.71.11.71.6-1.81.4-1.91.5-2.2
Intermitt. access day 15 inactive lever presses2.32.55.4-0.20.4-0.1-0.60.3-1.10.80.9-1.12.31.11.12.21.31.5-1.42.02.22.1-2.32.3-2.32.0-2.2
Intermitt. access escalation Index0.10.10.40.10.2-0.20.00.1-0.3-0.00.0-0.10.40.10.10.40.10.6-0.60.30.10.2-0.20.4-0.20.5-0.3
Intermittent access day 1 total infusions0.80.92.8-1.7-1.31.2-1.1-1.1-0.90.80.8-0.8-1.20.70.7-1.40.6-1.71.30.1-0.1-0.30.3-0.40.2-0.51.1
Intermittent access day 15 total infusions3.94.49.9-3.2-3.02.9-2.7-2.7-2.52.52.4-2.3-2.02.32.2-2.12.1-2.52.31.10.80.6-0.60.7-0.60.30.7
Intermittent access terminal intake (last 3 days)4.24.511.3-3.4-3.02.6-2.8-2.4-2.72.52.6-2.5-2.22.42.3-2.42.3-2.51.91.41.00.8-0.70.8-0.70.40.6
Intermittent access total infusions2.42.76.6-2.6-2.42.2-2.1-1.9-2.01.91.9-1.9-1.71.81.8-1.91.7-2.01.61.00.70.5-0.50.5-0.50.20.6
Intermittent access day 1 locomotion0.20.21.1-1.0-0.50.5-0.6-0.3-0.60.40.5-0.5-0.40.40.4-0.60.4-0.70.30.30.20.0-0.10.1-0.1-0.20.5
Intermittent access day 15 total locomotion0.50.62.5-1.1-0.90.8-0.7-0.5-0.60.50.5-0.5-1.50.40.4-1.60.3-1.21.0-0.1-0.2-0.40.4-0.00.5-0.60.9
Intermittent access total locomotion0.60.72.2-1.5-0.90.9-1.1-0.6-1.20.91.0-1.0-0.81.00.9-1.00.9-0.90.50.70.60.4-0.50.6-0.50.10.2
Intermittent access standard deviation4.85.07.8-2.1-2.42.3-2.7-2.2-2.62.82.8-2.8-0.62.82.8-0.72.8-0.70.72.42.42.2-2.22.5-2.12.1-1.4
Left kidney weight1.02.94.7-2.0-1.61.5-2.1-1.9-1.92.12.1-2.2-0.62.22.2-0.42.2-0.60.61.81.71.7-1.61.7-1.51.5-1.0
Right kidney weight0.92.64.2-1.2-0.91.0-1.7-1.2-1.61.81.9-2.0-0.52.02.0-0.32.00.3-0.32.02.02.0-2.01.7-1.91.8-1.6
Cocaine induced anxiety0.40.51.80.10.4-0.40.00.5-0.30.00.1-0.21.30.20.21.20.30.8-1.10.80.80.8-0.91.0-0.80.8-1.0
Post-drug Anxiety1.31.44.51.71.5-1.51.31.41.5-1.1-1.11.02.1-1.0-0.92.0-0.91.5-1.3-0.30.40.3-0.60.1-0.30.1-1.1
Baseline Anxiety0.40.40.90.50.5-0.20.50.10.7-0.5-0.60.6-0.6-0.7-0.7-0.5-0.7-0.10.7-1.0-0.7-0.70.7-0.90.7-0.80.6
Tail length0.30.82.31.21.5-1.51.01.21.1-0.9-0.90.80.8-0.8-0.80.9-0.81.2-0.8-0.5-0.20.00.0-0.1-0.4-0.2-0.6
Length with tail0.00.10.40.10.1-0.00.1-0.30.5-0.1-0.20.2-0.3-0.2-0.2-0.3-0.2-0.20.6-0.5-0.6-0.50.5-0.10.1-0.30.3
Length without tail0.51.13.3-0.9-1.41.4-0.8-1.7-0.10.60.5-0.4-1.60.40.4-1.60.3-1.61.8-0.5-0.9-0.91.0-0.20.9-0.51.4
Times rat made contact with spout0.10.10.4-0.5-0.20.2-0.3-0.1-0.40.30.3-0.3-0.00.30.3-0.00.3-0.20.00.30.60.1-0.50.2-0.20.1-0.1
Lifetime Intake2.52.96.5-2.6-2.32.2-2.2-1.9-2.12.02.1-2.0-1.52.01.9-1.71.9-1.81.41.21.00.8-0.80.8-0.90.50.3
Liver weight, left1.32.03.21.61.6-1.61.81.61.7-1.8-1.81.81.1-1.7-1.71.0-1.70.7-1.1-1.2-1.3-1.01.1-1.31.0-1.20.6
Liver weight, right0.20.31.10.50.5-0.50.30.70.0-0.2-0.10.00.6-0.1-0.00.60.00.8-1.10.50.60.6-0.60.7-0.40.5-0.5
Locomotor activity0.00.00.10.2-0.00.00.00.1-0.1-0.0-0.10.10.2-0.0-0.00.3-0.0-0.0-0.10.00.1-0.0-0.10.1-0.10.00.0
Locomotor testing distance0.00.10.50.1-0.1-0.00.20.1-0.3-0.2-0.20.20.3-0.2-0.20.4-0.2-0.10.0-0.2-0.0-0.70.2-0.10.1-0.20.4
Locomotor testing rearing0.50.82.4-1.1-1.11.0-1.1-1.0-1.51.01.0-1.0-0.31.01.0-0.31.0-0.80.60.80.7-0.0-0.40.7-0.70.50.2
Locomotion in novel chamber0.81.01.71.01.0-1.11.21.31.1-1.2-1.21.20.1-1.2-1.20.1-1.20.3-0.8-0.9-1.1-1.01.0-0.51.1-0.80.7
Locomotion in novel chamber post-restriction0.10.10.3-0.1-0.00.0-0.2-0.0-0.20.20.2-0.30.60.30.30.50.30.3-0.30.50.60.5-0.60.3-0.60.5-0.5
Fecal boli incidents, locomotor time 10.20.20.50.60.6-0.60.50.60.5-0.5-0.50.50.7-0.5-0.50.6-0.40.3-0.4-0.3-0.1-0.10.10.20.5-0.4-0.0
Change in fecal boli incidents, locomotor task1.61.53.8-1.5-1.71.6-1.4-1.7-1.61.31.3-1.2-2.01.21.2-1.91.1-1.41.30.4-0.00.00.20.6-0.40.20.6
Time >=10cm from walls, locomotor time 10.90.93.1-1.2-1.11.1-0.9-0.9-1.00.70.7-0.6-1.80.50.5-1.70.4-1.61.6-0.4-0.5-0.50.70.10.2-0.71.0
Bouts of movement, locomotor time 12.83.16.8-0.2-0.30.2-1.1-0.2-1.31.41.5-1.61.31.61.71.31.81.4-1.42.42.52.5-2.62.0-2.52.5-2.5
Total resting periods, locomotor time 11.92.14.5-0.1-0.40.3-1.0-0.3-1.21.21.3-1.40.91.41.40.91.51.1-1.01.92.02.0-2.11.7-2.12.1-2.0
Rest time, locomotor task time 11.11.22.5-0.2-0.60.6-1.0-0.9-1.01.11.2-1.20.21.21.30.21.30.5-0.51.41.41.5-1.41.1-1.41.6-1.4
Distance moved, locomotor task time 10.10.10.2-0.2-0.10.10.10.30.1-0.1-0.20.20.2-0.2-0.20.1-0.2-0.30.3-0.2-0.3-0.40.3-0.20.3-0.30.4
Vertical activity count, locomotor time 11.11.22.6-0.10.00.00.60.10.9-0.7-0.90.9-0.6-0.9-1.0-0.7-1.0-1.01.1-1.5-1.5-1.61.5-1.61.5-1.51.6
Time >=10cm from walls, locomotor time 21.01.02.7-1.0-0.70.7-0.2-0.6-0.30.0-0.00.1-1.6-0.2-0.2-1.5-0.3-1.61.6-1.0-1.2-1.11.3-1.20.6-1.31.5
Bouts of movement, locomotor time 22.02.15.00.60.4-0.5-0.40.5-0.60.60.7-0.91.80.91.01.81.11.8-1.81.92.02.0-2.11.6-2.02.1-2.2
Total resting periods, locomotor time 22.12.25.10.70.4-0.5-0.40.6-0.70.60.7-0.91.70.91.01.71.11.9-1.81.92.02.0-2.21.7-2.02.2-2.3
Rest time, locomotor task time 20.30.41.20.70.3-0.40.10.5-0.20.00.1-0.20.70.20.20.60.31.0-1.10.80.70.7-0.80.5-0.71.0-0.9
Distance moved, locomotor task time 20.10.10.3-0.5-0.30.2-0.3-0.1-0.30.30.3-0.30.10.30.30.10.3-0.00.00.30.30.3-0.30.2-0.40.2-0.2
Vertical activity count, locomotor time 21.11.21.90.70.9-0.91.20.81.4-1.3-1.31.30.3-1.3-1.40.2-1.40.0-0.0-1.3-1.2-1.21.2-1.41.4-1.20.8
Light reinforcement 10.71.24.41.31.3-1.50.71.50.9-0.6-0.40.31.5-0.3-0.31.4-0.21.8-2.10.81.10.9-1.20.7-1.00.9-1.3
Light reinforcement 21.41.84.31.92.1-2.01.61.91.5-1.5-1.41.21.6-1.2-1.21.5-1.11.9-2.0-0.20.30.3-0.5-0.2-0.2-0.0-0.7
Bone: marrow area1.22.56.1-0.8-0.80.80.0-0.70.3-0.3-0.40.6-2.4-0.6-0.7-2.3-0.8-2.12.2-1.9-2.5-1.72.4-2.01.8-2.22.2
Bone: maximum diameter0.10.30.8-0.7-0.70.7-0.5-0.4-0.50.40.4-0.3-0.90.30.3-0.90.2-0.80.6-0.10.0-0.40.0-0.30.1-0.40.6
Bone: maximum force0.81.33.4-0.3-0.10.00.50.10.7-0.7-0.70.8-1.4-0.9-0.9-1.3-1.0-1.21.0-1.5-1.5-1.41.5-1.71.5-1.81.7
Bone: maximum moment0.71.33.0-0.6-0.50.50.1-0.40.3-0.3-0.40.5-1.7-0.5-0.6-1.6-0.7-1.51.4-1.4-1.3-1.41.4-1.51.4-1.71.7
Mean time between licks in bursts1.52.13.81.11.0-1.11.60.91.7-1.7-1.71.8-0.0-1.8-1.80.1-1.80.00.1-1.9-2.0-1.51.8-1.71.8-1.61.2
Mean num. licks in bursts0.30.41.90.50.6-0.60.30.60.1-0.2-0.20.11.4-0.1-0.11.40.00.8-0.80.40.60.4-0.80.4-0.50.5-0.5
Cd content in liver1.41.54.21.01.1-1.10.41.00.1-0.10.0-0.11.60.10.21.90.32.1-1.91.11.51.4-1.51.3-1.41.5-1.9
Co content in liver0.80.92.90.60.5-0.5-0.00.2-0.10.20.3-0.31.60.40.41.70.51.3-1.11.00.91.1-1.11.2-1.21.4-1.5
Cu content in liver2.93.55.7-2.2-2.32.3-2.4-2.2-2.32.32.3-2.3-1.72.32.2-1.72.2-1.51.31.51.51.4-1.21.2-1.21.0-0.3
Fe content in liver2.22.67.8-0.5-0.40.40.4-0.40.7-0.7-0.80.9-1.9-1.0-1.0-1.9-1.1-1.81.8-1.9-2.8-2.32.8-2.02.1-2.12.4
K content in liver0.70.71.3-0.6-0.70.8-1.0-1.0-0.81.01.0-1.00.21.01.00.11.0-0.10.40.90.81.1-0.80.9-0.91.0-0.7
Mg content in liver0.20.20.6-0.6-0.70.7-0.6-0.8-0.40.60.5-0.5-0.30.50.5-0.30.5-0.60.70.20.00.5-0.00.2-0.10.2-0.0
Mn content in liver0.20.20.90.70.7-0.70.50.20.6-0.5-0.50.50.9-0.4-0.40.8-0.40.7-0.3-0.2-0.3-0.10.1-0.00.00.1-0.2
Na content in liver0.91.01.6-1.1-1.11.1-1.2-1.1-1.31.21.2-1.2-0.41.21.2-0.51.2-0.50.41.01.00.9-1.00.9-0.90.8-0.5
Rb content in liver0.10.20.60.20.0-0.1-0.10.3-0.10.10.2-0.20.70.20.20.80.30.4-0.50.50.30.8-0.50.5-0.50.5-0.6
Se content in liver0.20.30.5-0.5-0.20.3-0.5-0.5-0.60.60.6-0.6-0.20.60.6-0.00.60.2-0.00.60.70.4-0.60.6-0.70.6-0.5
Sr content in liver0.60.51.11.11.1-0.90.90.31.1-0.8-0.90.90.5-0.9-0.80.5-0.80.60.1-0.9-0.4-0.50.3-0.50.5-0.30.2
Zn content in liver1.41.62.6-1.3-1.21.4-1.5-1.4-1.51.51.5-1.5-0.81.51.5-0.71.5-0.50.71.11.61.3-1.51.1-1.01.0-0.6
Bone: minimum diameter3.26.012.70.40.5-0.51.70.82.0-2.0-2.12.3-2.0-2.3-2.4-1.9-2.5-1.81.6-3.3-3.4-3.33.4-3.43.2-3.63.3
Time in familiar zone, hab. session 11.31.22.5-0.5-0.80.8-1.0-1.0-1.01.11.1-1.20.91.21.20.91.30.3-0.21.51.51.1-1.41.3-1.31.6-1.1
Time in novel zone, hab. session 10.10.10.5-0.10.3-0.30.20.50.1-0.3-0.20.2-0.6-0.3-0.3-0.7-0.3-0.2-0.0-0.4-0.4-0.10.3-0.30.2-0.60.2
Total zone transitions, hab. session 11.11.62.71.41.2-1.21.51.21.6-1.5-1.61.60.4-1.6-1.60.2-1.60.5-0.3-1.3-1.1-1.51.1-1.31.2-1.10.9
Total locomotion distance, hab. session 11.11.63.60.80.6-0.61.10.71.3-1.3-1.31.4-0.3-1.4-1.4-0.4-1.5-0.50.4-1.6-1.5-1.91.7-1.61.8-1.51.6
Locomotion velocity, hab. session 11.52.24.11.11.0-0.91.51.11.7-1.6-1.71.7-0.1-1.7-1.7-0.2-1.8-0.20.2-1.8-1.6-2.01.7-1.81.9-1.71.6
Time in familiar zone, hab. session 23.33.45.5-1.1-1.41.4-1.9-1.7-1.92.02.0-2.10.72.12.10.72.20.2-0.12.22.32.3-2.32.2-2.12.3-1.8
Time in novel zone, hab. session 21.71.73.50.40.8-0.81.11.01.2-1.3-1.31.3-1.0-1.4-1.4-1.0-1.5-0.50.3-1.6-1.7-1.91.7-1.71.5-1.81.6
Total zone transitions, hab. session 20.30.41.71.00.7-0.70.60.70.5-0.5-0.50.41.3-0.4-0.41.2-0.30.9-0.80.1-0.2-0.00.10.3-0.30.4-0.6
Total locomotion distance, hab. session 20.30.40.80.50.4-0.50.70.60.6-0.7-0.70.70.5-0.7-0.70.4-0.70.0-0.1-0.6-0.9-0.80.8-0.60.6-0.60.5
Locomotion velocity, hab. session 20.20.30.60.40.3-0.40.50.50.5-0.6-0.60.60.5-0.6-0.60.4-0.60.0-0.1-0.5-0.8-0.50.7-0.50.5-0.50.4
Novel to familiar place preference ratio0.30.31.3-0.10.2-0.20.30.30.3-0.4-0.40.4-0.7-0.4-0.5-0.4-0.5-0.30.4-0.7-1.1-0.21.0-0.70.5-0.80.5
Novelty place preference0.10.10.6-0.30.1-0.00.10.20.0-0.1-0.10.1-0.6-0.1-0.2-0.3-0.2-0.30.3-0.4-0.8-0.00.7-0.40.2-0.50.2
Time in novel zone, NPP test0.00.00.2-0.30.1-0.10.00.2-0.1-0.00.00.0-0.5-0.0-0.1-0.2-0.0-0.10.0-0.1-0.40.20.4-0.2-0.1-0.2-0.0
Total zone transitions, NPP test0.60.82.11.41.2-1.21.11.11.0-1.0-1.00.91.4-0.9-0.91.3-0.81.2-0.9-0.3-0.2-0.60.2-0.20.10.1-0.3
Total locomotion distance, NPP test0.70.91.50.80.7-0.81.10.91.0-1.1-1.11.20.2-1.2-1.20.1-1.20.0-0.1-1.1-1.1-1.21.2-1.11.2-1.01.0
Locomotion velocity, NPP test0.60.81.70.50.4-0.50.80.60.8-0.9-1.01.0-0.0-1.0-1.0-0.2-1.0-0.40.3-1.1-1.3-1.21.3-1.21.2-1.11.1
Intraocular pressure2.02.85.41.91.9-1.82.11.82.3-2.1-2.12.10.3-2.1-2.10.3-2.10.8-0.6-1.7-1.6-1.41.5-1.71.4-1.40.7
Delta distance traveled before/after self-admin0.40.42.1-1.1-0.60.7-0.8-0.7-0.50.70.7-0.7-1.10.70.6-1.40.6-0.70.60.20.20.2-0.10.2-0.2-0.10.2
Delta ambulatory time before/after self-admin0.91.03.1-1.5-1.01.0-1.2-1.1-1.11.11.2-1.1-1.51.11.0-1.81.0-0.80.70.60.50.5-0.30.5-0.60.20.0
Parametrial fat weight0.20.52.71.00.9-0.60.40.70.7-0.3-0.30.31.6-0.2-0.21.4-0.10.9-0.60.1-0.00.6-0.20.4-0.40.5-0.9
Pavlov. Cond. lever latency0.70.91.5-0.9-0.90.9-1.1-0.8-1.21.21.2-1.2-0.11.21.2-0.01.2-0.20.31.10.81.2-0.71.0-1.10.9-0.8
Pavlov. Cond. magazine entry latency0.50.71.10.50.6-0.60.90.71.0-1.0-1.01.0-0.2-1.0-1.0-0.1-1.0-0.0-0.1-1.0-0.9-1.00.9-1.11.0-0.90.7
Pavlov. Cond. change in total contacts2.42.64.61.71.7-1.72.01.82.1-2.0-2.02.00.1-2.0-2.0-0.0-2.00.7-0.8-1.7-1.4-1.61.3-1.51.6-1.41.0
Pavlov. Cond. index score0.70.91.51.01.1-1.11.21.01.2-1.2-1.21.20.4-1.2-1.20.4-1.10.6-0.6-0.8-0.6-0.90.5-0.80.8-0.60.5
Pavlov. Cond. latency score0.60.81.41.01.0-1.01.11.01.2-1.1-1.11.10.5-1.1-1.10.5-1.00.6-0.7-0.7-0.5-0.80.4-0.70.7-0.50.4
Pavlov. Cond. lever contacts1.31.52.50.91.0-0.91.30.91.5-1.4-1.41.5-0.3-1.5-1.5-0.3-1.5-0.0-0.0-1.5-1.3-1.61.2-1.41.5-1.31.3
Pavlov. Cond. magazine entry number0.60.71.2-1.0-1.01.0-1.1-1.1-1.11.11.1-1.0-0.31.01.0-0.31.0-0.70.70.70.50.7-0.40.6-0.70.5-0.3
Pavlov. Cond. intertrial magazine entries0.20.30.8-0.7-0.80.8-0.6-0.9-0.50.50.4-0.4-0.60.40.4-0.70.3-0.90.9-0.1-0.40.30.4-0.10.3-0.10.4
Pavlov. Cond. lever-magazine prob. diff.0.70.81.51.01.1-1.11.21.01.2-1.2-1.11.10.3-1.1-1.10.3-1.10.6-0.6-0.8-0.6-0.80.5-0.80.8-0.60.4
Pavlov. Cond. response bias1.01.32.01.01.0-1.01.31.01.4-1.3-1.31.4-0.2-1.4-1.4-0.2-1.40.2-0.2-1.3-1.2-1.31.1-1.21.3-1.11.0
Pavlov. Cond. lever latency0.81.02.21.41.5-1.51.21.41.2-1.0-1.01.01.4-1.0-0.91.4-0.81.3-1.1-0.4-0.30.40.1-0.2-0.0-0.0-0.7
Pavlov. Cond. magazine entry latency0.00.00.1-0.2-0.10.0-0.00.0-0.0-0.0-0.00.0-0.3-0.1-0.1-0.2-0.1-0.30.1-0.1-0.30.10.3-0.20.2-0.30.2
Pavlov. Cond. change in total contacts1.42.05.0-0.4-0.30.30.5-0.40.7-0.7-0.80.9-1.6-1.0-1.0-1.6-1.1-1.61.5-1.8-1.8-2.21.9-1.92.0-2.02.2
Pavlov. Cond. index score0.60.82.1-0.6-0.60.5-0.0-0.40.1-0.2-0.20.3-1.3-0.3-0.4-1.3-0.5-1.31.1-0.9-1.1-1.21.2-1.11.2-1.21.5
Pavlov. Cond. latency score0.50.61.6-0.8-0.70.6-0.2-0.6-0.20.10.10.0-1.3-0.0-0.1-1.3-0.2-1.21.0-0.6-0.8-0.80.9-0.80.8-0.91.2
Pavlov. Cond. lever contacts0.50.71.6-1.1-1.21.2-0.8-1.1-0.70.70.6-0.6-1.20.60.5-1.20.4-1.31.1-0.0-0.1-0.80.3-0.20.3-0.30.9
Pavlov. Cond. magazine entry number0.20.20.60.1-0.10.1-0.3-0.1-0.30.40.4-0.40.50.40.40.50.50.4-0.30.60.80.4-0.70.7-0.70.7-0.6
Pavlov. Cond. intertrial magazine entries0.40.61.00.70.5-0.50.80.61.0-0.8-0.90.90.1-0.9-0.90.1-0.90.00.1-0.9-1.0-0.91.0-0.80.7-0.80.5
Pavlov. Cond. lever-magazine prob. diff.0.60.71.9-0.7-0.60.6-0.1-0.5-0.0-0.1-0.10.2-1.3-0.2-0.2-1.3-0.3-1.31.1-0.8-0.9-1.11.0-1.01.1-1.11.4
Pavlov. Cond. response bias0.60.92.3-0.9-0.80.8-0.3-0.8-0.20.10.00.0-1.5-0.1-0.1-1.5-0.2-1.41.2-0.8-0.9-1.31.1-1.01.0-1.11.5
Time in closed arm before self-admin0.40.50.7-0.9-0.50.7-0.8-0.7-0.10.80.8-0.9-0.30.80.8-0.50.8-0.20.20.70.70.7-0.70.7-0.70.6-0.5
Time in closed arm after self-admin1.01.01.8-0.5-0.60.8-1.0-0.8-0.31.11.1-1.10.11.21.2-0.11.20.3-0.11.21.41.3-1.31.3-1.31.3-1.2
Time in open arm before self-admin0.70.82.1-0.1-0.1-0.10.4-0.10.3-0.6-0.70.7-0.5-0.7-0.8-0.6-0.8-1.00.9-1.2-1.3-1.31.3-1.21.2-1.41.4
Time in open arm after self-admin0.70.81.71.01.1-1.31.11.20.4-1.2-1.11.10.4-1.1-1.10.6-1.10.5-0.8-0.8-0.6-0.60.6-0.70.5-0.70.3
Bone: periosteal estimation1.73.57.8-0.5-0.50.50.5-0.20.8-0.8-0.91.1-2.6-1.2-1.2-2.4-1.4-2.21.9-2.4-2.6-2.52.7-2.62.4-2.82.8
Bone: periosteal perimeter0.40.72.4-0.9-0.80.9-0.4-0.7-0.40.20.2-0.1-1.60.10.0-1.5-0.1-1.41.2-0.7-0.7-0.70.7-0.80.7-1.01.2
Bone: post-yield work2.02.75.4-2.3-2.22.2-2.0-2.2-1.91.91.9-1.8-2.01.71.7-2.21.6-1.91.80.80.60.3-0.40.5-0.40.20.5
Progressive ratio test 1 active lever presses3.63.75.9-2.0-1.61.6-2.2-1.4-2.32.22.3-2.40.22.42.40.02.4-0.3-0.12.42.42.2-2.31.9-2.11.9-1.4
Progressive ratio test 1 breakpoint3.13.35.2-2.1-1.71.6-2.1-1.3-2.32.12.2-2.3-0.12.32.2-0.22.3-0.5-0.02.22.11.9-2.01.6-1.91.6-1.1
Progressive ratio test 1 inactive lever presses1.01.12.8-0.4-0.00.1-0.6-0.0-0.60.70.7-0.81.40.80.81.30.90.7-0.51.11.61.5-1.71.1-1.71.1-1.5
Progressive ratio test 2 active lever presses1.61.73.9-2.0-1.91.9-1.7-1.7-1.41.61.5-1.5-1.21.51.4-1.31.4-1.71.50.70.60.5-0.50.3-0.40.20.4
Progressive ratio test 2 breakpoint1.41.63.5-1.9-1.81.9-1.6-1.7-1.31.41.3-1.3-1.31.31.2-1.51.1-1.81.60.40.30.1-0.10.0-0.1-0.10.7
Progressive ratio test 2 inactive lever presses1.01.13.3-1.8-1.51.4-1.4-1.1-1.41.31.3-1.2-0.41.21.2-0.61.2-1.21.10.80.70.5-0.60.7-0.70.20.2
Incentive Sensitization - Responses1.61.74.8-1.1-1.31.4-0.6-1.2-0.30.30.2-0.1-1.80.10.0-1.9-0.1-2.22.1-0.9-1.4-1.41.5-1.21.6-1.32.0
Incentive Sensitization - Breakpoint1.51.54.3-1.2-1.41.4-0.7-1.2-0.40.50.3-0.2-1.80.20.2-1.80.0-2.12.0-0.8-1.2-1.21.4-1.11.4-1.11.8
Sum of active levers in priming session hrs 5-60.50.51.4-0.2-0.50.40.1-0.30.3-0.2-0.30.3-0.9-0.3-0.3-1.0-0.4-0.90.8-0.7-1.0-1.01.1-0.90.8-0.81.2
Progressive ratio1.72.05.8-1.0-1.00.9-1.4-0.7-2.01.51.6-1.70.31.71.70.31.70.2-0.31.91.51.6-1.52.4-1.21.7-1.2
Food seeking constrained by brief footshock3.03.76.02.21.9-1.82.42.22.3-2.4-2.42.40.6-2.4-2.40.7-2.50.6-0.5-2.1-1.9-1.91.8-1.61.7-1.91.1
Seeking ratio, punishment vs. effort4.45.39.72.32.0-1.82.71.83.1-2.7-2.82.90.2-2.8-2.80.3-2.90.3-0.1-2.9-2.4-2.42.3-3.02.0-2.41.5
Retroperitoneal fat weight0.00.10.40.1-0.20.3-0.4-0.30.00.40.4-0.40.00.40.4-0.10.40.10.10.3-0.00.7-0.20.3-0.60.5-0.4
Reaction time number correct0.60.81.8-0.7-0.70.8-0.1-0.70.4-0.1-0.20.3-1.3-0.3-0.3-1.2-0.4-1.31.3-1.1-1.2-1.31.3-0.81.0-1.31.3
Reaction time mean minus median1.72.27.21.81.9-1.81.42.11.2-1.3-1.21.02.7-1.0-0.92.6-0.82.2-2.40.40.80.4-0.90.5-0.20.7-1.1
Reaction time mean minus median AUC2.02.66.41.92.2-2.11.82.51.6-1.7-1.61.42.5-1.4-1.42.4-1.22.1-2.40.00.5-0.0-0.6-0.00.30.2-0.7
Reaction time num false alarms1.21.74.8-1.3-1.11.1-0.4-1.0-0.30.20.10.1-2.0-0.1-0.2-2.0-0.3-2.22.1-1.2-1.3-1.31.5-1.41.4-1.61.9
Reaction time num false alarms AUC1.01.44.2-1.2-1.11.1-0.5-1.0-0.60.20.2-0.1-1.80.0-0.0-1.9-0.1-2.01.9-1.0-1.0-1.21.3-1.21.2-1.41.7
Reaction time trials correct on left0.60.81.8-0.7-0.70.8-0.1-0.70.4-0.1-0.20.3-1.3-0.3-0.3-1.2-0.4-1.31.3-1.1-1.2-1.31.3-0.81.0-1.31.3
Reaction time trials on left0.60.81.8-0.6-0.60.70.0-0.60.4-0.2-0.30.4-1.3-0.4-0.4-1.1-0.5-1.31.2-1.1-1.3-1.31.4-0.81.1-1.31.4
Reaction time mean1.31.94.71.61.8-1.71.72.21.4-1.7-1.71.61.7-1.6-1.51.5-1.41.4-1.5-0.6-0.4-0.40.3-0.60.9-0.5-0.0
Reaction time mean AUC1.62.15.11.61.9-1.81.82.31.5-1.8-1.81.71.6-1.7-1.71.5-1.61.3-1.5-0.8-0.5-0.60.4-0.81.0-0.70.1
Median of all reaction times1.41.94.01.51.6-1.51.82.01.4-1.8-1.81.71.0-1.7-1.70.9-1.70.9-1.0-1.1-1.0-0.80.8-1.11.3-1.00.5
Reaction time omissions2.23.08.12.32.5-2.72.22.91.3-2.1-1.91.71.9-1.7-1.71.8-1.62.4-2.7-0.30.4-0.4-0.3-0.20.3-0.1-0.7
Reaction time false alarm rate0.10.10.5-0.5-0.50.4-0.4-0.4-0.70.30.3-0.3-0.40.30.3-0.60.2-0.70.70.00.0-0.10.1-0.30.1-0.20.3
Reaction time premature initiation rate1.52.03.4-1.3-1.41.5-1.8-1.5-1.51.81.8-1.8-0.91.81.8-1.01.8-0.40.61.61.21.1-1.21.3-1.01.5-0.6
Reaction time premature initiations1.11.62.9-1.5-1.61.7-1.6-1.7-1.21.61.6-1.5-1.41.51.5-1.41.4-1.01.11.00.60.4-0.40.9-0.50.70.1
Std. dev. reaction times1.11.54.91.31.6-1.51.21.90.8-1.1-1.00.82.2-0.8-0.82.1-0.71.8-2.00.40.70.4-0.80.3-0.10.5-0.9
Reaction time trials completed0.60.81.8-0.6-0.60.70.0-0.60.4-0.2-0.30.4-1.3-0.4-0.4-1.1-0.5-1.31.2-1.1-1.3-1.31.4-0.81.1-1.31.4
Reaction time trials AUC0.60.92.1-0.6-0.40.60.1-0.50.6-0.3-0.40.5-1.3-0.5-0.5-1.1-0.6-1.21.1-1.2-1.4-1.41.4-1.01.1-1.41.4
Run reversals in cocaine runway, females0.40.41.31.10.9-0.90.71.00.5-0.7-0.60.60.2-0.6-0.60.2-0.50.8-0.9-0.2-0.0-0.10.00.7-0.00.0-0.2
Run reversals in cocaine runway, males2.92.84.41.81.8-1.82.01.81.9-2.1-2.02.00.6-2.0-2.00.6-2.01.0-1.1-1.5-1.7-1.71.6-1.51.6-1.20.9
Latency to leave start box in cocaine runway0.40.51.0-1.0-0.90.9-0.8-1.0-0.90.70.7-0.6-0.80.60.6-0.80.6-0.70.90.2-0.4-0.20.4-0.10.40.10.6
Latency to leave start box in cocaine runway, F1.81.94.4-2.0-1.91.9-1.7-2.1-1.91.61.6-1.5-1.61.51.4-1.61.4-1.41.60.6-0.20.00.30.20.20.40.7
Latency to leave start box in cocaine runway, M1.51.42.41.61.6-1.61.51.51.5-1.5-1.41.41.1-1.4-1.31.1-1.31.1-1.2-0.8-0.7-0.70.6-0.80.7-0.50.1
Std. dev. time between licks in bursts0.40.51.30.1-0.20.10.3-0.20.4-0.4-0.40.5-1.0-0.5-0.5-1.0-0.6-0.50.7-1.0-1.1-1.01.1-0.90.9-0.80.9
Total sessions with >9 infusions1.41.52.5-1.4-0.90.8-1.4-0.6-1.41.41.5-1.5-0.21.51.5-0.21.5-0.2-0.31.61.61.4-1.51.1-1.41.2-0.9
Short access day 1 total inactive lever presses0.91.01.8-0.9-0.50.7-0.9-0.5-0.91.01.0-1.00.81.11.10.81.10.1-0.21.21.31.2-1.31.1-1.31.1-1.0
Short access day 10 total inactive lever presses1.01.13.30.50.3-0.1-0.10.1-0.20.40.4-0.41.80.50.61.70.61.4-0.81.01.41.4-1.51.3-1.71.5-1.8
Short access day 1 total infusions2.02.23.4-1.6-1.61.6-1.8-1.3-1.81.81.8-1.8-1.21.81.8-1.31.8-0.70.41.61.31.2-1.21.4-1.41.2-0.6
Short access day 10 total infusions2.12.34.1-2.0-1.61.6-1.9-1.5-2.01.91.9-1.9-0.61.91.9-0.71.9-0.90.71.51.41.2-1.31.4-1.41.1-0.4
Short access total infusions2.22.55.0-2.2-1.81.8-2.0-1.5-2.01.92.0-2.0-1.01.91.9-1.11.9-1.10.81.51.51.2-1.31.1-1.50.9-0.4
Short access day 1 locomotion0.80.92.2-0.8-0.40.4-0.8-0.0-0.90.80.9-1.00.31.01.00.31.00.2-0.61.31.51.2-1.41.0-1.40.9-1.0
Short access day 10 total locomotion0.80.82.60.91.2-1.30.71.30.5-0.6-0.40.31.3-0.3-0.31.2-0.21.5-1.60.50.80.7-0.90.9-0.90.5-1.0
Short access total locomotion0.60.71.4-1.1-0.60.4-0.9-0.3-0.90.80.9-0.90.30.90.90.20.9-0.2-0.21.01.21.0-1.10.9-1.20.5-0.6
One hour access (0.3 mA shock)2.73.27.3-2.5-2.72.6-2.1-2.5-1.71.91.8-1.7-2.21.71.6-2.41.5-2.52.40.4-0.0-0.10.30.20.1-0.11.2
Compulsive drug intake1.11.12.51.61.2-1.21.30.81.6-1.1-1.21.21.4-1.1-1.11.4-1.01.1-0.6-0.7-0.6-0.40.4-1.00.3-0.0-0.3
One hour access (shock baseline)4.65.312.0-3.5-3.33.1-2.9-2.8-2.92.72.7-2.6-2.52.52.4-2.62.3-2.82.31.30.80.6-0.51.3-0.50.30.8
Social response proportion0.30.41.70.40.5-0.50.20.5-0.3-0.1-0.10.01.3-0.00.01.30.10.8-0.80.50.70.6-0.70.5-0.40.5-0.8
Social responses0.60.82.70.71.0-1.00.51.1-0.1-0.4-0.30.21.6-0.2-0.21.6-0.11.3-1.50.71.10.6-1.10.7-0.50.7-1.1
Social time0.10.10.3-0.5-0.1-0.10.00.2-0.3-0.1-0.10.10.2-0.1-0.10.3-0.1-0.40.1-0.1-0.0-0.40.1-0.30.4-0.40.5
Soleus weight0.61.63.31.61.7-1.81.61.71.6-1.6-1.51.51.4-1.5-1.41.4-1.41.1-1.3-0.8-0.4-1.00.2-0.80.6-0.60.2
Bone: stiffness0.20.31.0-0.20.1-0.10.30.10.3-0.4-0.30.4-1.0-0.4-0.5-0.9-0.5-0.50.3-0.7-0.7-0.50.8-0.70.8-0.90.7
Tibialis anterior weight5.819.932.85.75.6-5.55.75.35.5-5.6-5.65.52.8-5.4-5.42.8-5.33.3-3.0-3.9-3.6-3.23.2-3.33.0-2.80.9
Time to tail flick, vehicle, before self-admin0.60.61.8-0.6-1.21.1-0.7-1.0-0.70.70.5-0.4-1.10.40.4-1.20.3-1.21.3-0.3-0.3-0.30.4-0.30.3-0.40.6
Time to tail flick, vehicle, after self-admin1.31.43.5-1.5-1.61.9-1.4-1.8-1.31.31.2-1.1-1.61.11.1-1.70.9-1.51.90.00.20.1-0.00.0-0.0-0.10.5
Time to tail flick, test, before self-admin1.01.02.4-0.00.1-0.1-0.5-0.1-0.70.60.7-0.80.90.80.80.60.91.0-1.01.31.41.4-1.41.4-1.51.4-1.4
Time to tail flick, test, after self-admin1.01.12.3-1.3-0.90.7-1.2-0.8-1.51.11.2-1.3-0.71.21.2-0.81.2-0.30.01.11.11.1-1.01.0-1.20.8-0.6
Delta time to tail flick, vehicle, before/after SA0.60.61.6-1.3-0.91.2-0.9-1.1-0.50.80.8-0.7-0.80.70.7-0.80.7-1.01.10.20.10.1-0.00.0-0.2-0.00.4
Delta time to tail flick, test, before/after SA0.20.20.4-0.3-0.10.1-0.40.1-0.50.40.5-0.5-0.40.50.5-0.30.50.2-0.30.60.60.7-0.60.5-0.70.5-0.6
Tibia length1.02.74.7-2.1-2.22.0-2.1-2.0-2.02.12.1-2.0-1.32.02.0-1.21.9-1.41.51.20.71.4-0.71.0-1.30.8-0.6
Ambulatory time before self-admin0.10.11.20.3-0.10.3-0.1-0.20.20.20.1-0.10.90.20.21.10.20.2-0.10.30.10.2-0.3-0.1-0.30.5-0.3
Ambulatory time after self-admin0.30.30.6-0.8-0.40.7-0.8-0.7-0.70.70.7-0.7-0.20.70.7-0.40.7-0.30.20.60.40.4-0.30.6-0.60.4-0.1
Bone: tissue strength2.02.04.0-2.0-1.51.5-1.8-1.6-1.91.71.8-1.7-0.71.71.7-0.71.7-0.90.91.31.31.2-1.21.1-1.20.9-0.5
Total heroin consumption0.30.40.80.40.3-0.30.60.30.7-0.7-0.70.70.0-0.7-0.70.1-0.8-0.30.3-0.9-0.8-0.80.7-0.80.6-0.90.7
Bone: trabecular number0.50.82.4-1.0-1.31.2-0.9-1.2-0.70.70.7-0.6-1.50.60.6-1.50.5-1.31.1-0.00.2-0.4-0.1-0.10.5-0.31.0
Bone: trabecular spacing0.81.03.01.21.3-1.30.91.30.8-0.7-0.60.61.7-0.5-0.51.7-0.41.6-1.60.40.10.5-0.30.4-0.60.6-1.1
Bone: trabecular thickness1.61.97.1-1.6-1.71.6-0.9-1.5-0.70.70.6-0.5-2.70.40.4-2.50.2-2.32.0-0.7-0.4-1.40.8-0.91.2-1.11.9
Bone: trabecular tissue density1.21.85.21.71.9-1.91.42.01.1-1.2-1.10.91.7-0.9-0.91.9-0.82.1-2.30.30.70.6-0.80.3-0.40.5-1.2
Water consumed over 24 hours0.10.10.20.20.4-0.40.40.40.2-0.4-0.40.30.0-0.4-0.4-0.0-0.30.2-0.3-0.2-0.0-0.30.2-0.30.2-0.20.0
Number of responses in last shaping day0.40.41.4-0.7-0.10.0-0.50.0-0.60.50.6-0.60.40.60.60.30.70.2-0.60.91.00.9-1.00.8-1.20.6-0.8