Hub : Genes

Eef1g

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Eef1g 0.19 0.11 1.1e-04 0.16 0.13 0.12 0.11 1.5e-04 6.1e-04 8.3e-04 1.5e-03
2 NAcc mRNA stability Eef1g 0.01 0.01 7.5e-03 0 0 0 0 3.3e-01 5.5e-02 3.0e-01 2.4e-01
3 Adipose mRNA stability Eef1g 0.04 0.02 5.1e-05 0.03 0.02 0.02 0.02 2.0e-04 4.7e-03 4.4e-03 1.2e-03
4 Brain mRNA stability Eef1g 0.1 0.06 5.1e-12 0.14 0.12 0.12 0.14 3.3e-13 1.1e-11 2.5e-11 1.2e-12
5 Liver mRNA stability Eef1g 0.06 0.04 9.2e-05 0.02 0.02 0.03 0.02 1.1e-03 2.8e-03 6.3e-04 2.5e-03
6 Liver intron excision ratio chr1_215289829_215290826 0.28 0.11 0.0e+00 0.16 0.16 0.15 0.16 1.7e-17 3.9e-17 1.1e-16 1.7e-17
7 Brain gene expression Eef1g 0.03 0.02 1.9e-03 0.03 0.03 0.03 0.03 5.9e-04 6.9e-04 1.3e-03 1.2e-03
8 Liver intron excision ratio chr1_215290631_215290826 0.3 0.11 0.0e+00 0.19 0.18 0.18 0.18 2.5e-20 8.3e-20 4.1e-19 4.0e-20
9 pVTA gene expression Eef1g 0.03 0.03 2.9e-03 0.03 0.01 0.02 0.02 2.9e-03 1.9e-02 1.1e-02 1.9e-02
10 PL mRNA stability Eef1g 0.04 0.02 4.0e-05 0.04 0.04 0.04 0.04 4.5e-05 1.9e-05 3.1e-05 5.2e-05
11 Liver gene expression Eef1g 0.04 0.03 1.6e-03 0.01 0.02 0.01 0.01 1.6e-02 5.5e-03 3.4e-02 1.3e-02
12 LHb mRNA stability Eef1g 0.32 0.31 4.0e-03 0.08 0.07 0.05 0.07 6.6e-03 1.1e-02 2.1e-02 8.8e-03
13 IC mRNA stability Eef1g 0.2 0.11 1.8e-04 0.02 0.04 0.09 0.05 3.2e-02 6.0e-03 2.1e-04 4.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.20.40.90.7-0.30.60.90.5-0.60.7-0.70.6-1.0-0.40.70.5
Area under the delay curve0.10.21.00.1-0.00.20.1-0.2-0.40.4-0.40.4-0.4-0.60.41.0
BMI with tail1.86.212.52.8-1.72.82.70.8-2.62.6-2.62.6-3.5-2.32.51.9
BMI without tail0.31.83.51.1-0.91.21.00.2-1.51.4-1.41.5-1.6-1.71.31.9
Body weight2.912.518.23.8-3.13.83.72.0-3.93.8-3.83.9-4.3-3.53.62.0
Weight adjusted by age0.20.71.21.1-0.91.11.10.7-0.80.7-0.70.6-1.0-0.50.90.1
Bone surface1.42.84.92.1-1.41.92.21.3-1.71.7-1.71.7-2.2-0.91.60.1
Bone volume0.51.02.31.3-0.71.21.50.7-0.91.0-1.00.9-1.4-0.20.9-0.3
Breakpoint value in progressive ratio session1.12.13.61.7-1.91.71.71.4-1.31.4-1.41.3-1.4-1.21.4-0.3
Number of licking bursts0.00.00.20.2-0.0-0.0-0.1-0.2-0.30.4-0.40.3-0.0-0.1-0.0-0.1
Context. condit. distance diff. score0.30.31.6-0.80.7-0.5-0.7-0.60.3-0.00.0-0.10.2-0.0-0.21.3
Locomotion velocity, session 10.30.32.7-0.1-0.10.1-0.20.4-0.40.4-0.40.4-0.2-0.70.41.7
Locomotion distance, session 10.91.23.40.6-0.60.90.60.4-1.11.2-1.21.4-1.1-1.31.01.8
Locomotion velocity, session 22.22.64.11.7-1.62.01.60.5-1.71.8-1.81.9-1.9-1.61.40.8
Locomotion distance, session 20.40.61.50.3-0.60.60.2-0.2-0.80.9-0.91.0-0.6-1.10.61.2
Locomotion velocity, session 30.50.61.90.5-0.10.50.4-0.2-0.80.9-0.90.8-1.0-0.80.71.4
Locomotion distance, session 30.20.20.90.2-0.20.20.20.5-0.50.4-0.40.3-0.3-0.60.51.0
Stereotopy head waving bouts, day 30.30.43.1-0.60.7-0.2-0.5-1.80.10.2-0.20.2-0.2-0.0-0.40.9
Stereotopy head waving duration, day 30.30.42.3-0.50.5-0.1-0.5-1.5-0.00.4-0.40.4-0.2-0.2-0.21.0
Locomotion velocity, session 70.10.11.2-0.20.20.2-0.1-1.1-0.10.4-0.40.3-0.2-0.0-0.20.3
Locomotion distance, session 70.20.21.7-0.40.3-0.2-0.2-0.7-0.20.2-0.20.1-0.1-0.50.01.3
Stereotopy head waving bouts, day 70.10.10.30.4-0.10.50.3-0.1-0.20.5-0.50.5-0.50.1-0.0-0.4
Stereotopy head waving duration, day 71.21.52.01.4-1.21.41.30.9-1.21.4-1.41.4-1.4-0.91.10.1
Locomotion velocity, session 80.20.31.9-0.4-0.10.0-0.3-0.0-0.30.4-0.40.30.1-0.80.21.4
Locomotion distance, session 80.30.41.8-0.80.9-0.5-0.8-1.30.30.0-0.0-0.00.20.2-0.50.9
Degree of sensitization distance0.10.11.1-0.30.6-0.1-0.1-1.10.00.1-0.10.1-0.30.0-0.20.4
Degree of sensitization stereotypy0.60.61.41.1-0.81.21.00.5-0.70.8-0.80.9-1.0-0.20.5-0.6
Conditioned locomotion0.60.70.90.8-0.80.90.80.3-0.90.9-0.90.9-0.9-0.90.80.7
Cocaine response after cond. corrected0.30.52.5-1.10.7-0.7-0.9-0.40.3-0.10.1-0.10.5-0.2-0.21.6
Cocaine response after cond. not corrected0.20.30.9-0.80.7-0.5-0.60.10.4-0.40.4-0.30.50.2-0.20.9
Cocaine response before conditioning0.50.62.70.9-0.40.80.81.30.1-0.40.4-0.4-0.30.60.1-1.6
Saline control response3.04.25.62.0-2.12.11.92.0-2.42.2-2.22.2-1.9-2.22.01.2
Bone: connectivity density1.52.43.81.7-1.31.61.81.3-1.51.5-1.51.4-2.0-1.31.61.0
Bone: cortical apparent density0.30.51.10.5-0.90.60.61.0-0.60.9-0.90.8-0.4-0.50.60.2
Bone: cortical area0.60.91.71.3-0.91.21.30.7-1.00.9-0.90.9-1.1-0.40.8-0.5
Bone: cortical porosity0.00.10.2-0.2-0.30.0-0.1-0.50.10.1-0.10.10.30.1-0.3-0.3
Bone: cortical porosity0.10.10.20.1-0.50.30.1-0.2-0.20.4-0.40.30.0-0.30.10.2
Bone: cortical thickness3.35.57.72.4-2.82.42.42.7-2.52.3-2.32.4-2.0-2.42.41.0
Bone: cortical thickness0.70.92.30.7-1.00.70.71.5-0.90.8-0.80.9-0.5-1.11.01.3
Bone: cortical tissue density0.40.71.40.6-1.00.80.81.2-0.81.0-1.01.0-0.5-0.70.70.3
Condit. Reinf. active minus inactive responses0.91.01.51.2-1.01.21.01.2-0.90.9-0.90.9-1.1-0.81.10.3
Condit. Reinf. active-inactive response ratio0.60.61.70.8-0.90.70.61.3-0.60.7-0.70.7-0.6-0.70.90.6
Condit. Reinf. active responses0.50.61.41.2-0.71.20.90.5-0.60.6-0.60.7-1.1-0.30.7-0.4
Condit. Reinf. inactive responses0.30.41.70.10.5-0.0-0.0-0.90.5-0.60.6-0.4-0.10.9-0.5-1.3
Incentive salience index mean1.01.31.91.4-1.01.31.21.2-1.11.1-1.11.1-1.4-0.91.20.5
Condit. Reinf. lever presses0.60.91.61.2-0.71.11.10.7-1.01.0-1.01.0-1.3-0.60.90.2
Condit. Reinf. active minus inactive responses0.30.41.8-0.30.5-0.2-0.3-0.50.6-0.50.5-0.50.51.1-0.8-1.3
Condit. Reinf. active-inactive response ratio0.91.43.6-0.71.1-0.5-0.7-1.91.2-0.90.9-0.90.61.7-1.4-1.9
Condit. Reinf. active responses0.10.10.30.3-0.30.40.30.5-0.30.3-0.30.3-0.10.10.1-0.5
Condit. Reinf. inactive responses0.50.83.70.5-0.70.50.51.9-0.90.7-0.70.6-0.3-1.00.91.0
Condit. Reinf. lever presses0.60.81.61.3-0.81.21.21.2-0.80.7-0.70.7-1.1-0.30.9-0.5
Condit. Reinf. lever reinforcers received0.20.20.60.5-0.50.70.50.8-0.40.5-0.50.4-0.3-0.00.3-0.5
Conditioned reinforcement - actives0.31.24.5-0.40.7-0.5-0.4-1.21.2-1.11.1-1.10.61.5-0.9-2.1
Conditioned reinforcement - inactives0.20.62.2-0.10.8-0.2-0.2-1.00.8-0.70.7-0.70.01.3-0.6-1.5
Conditioned locomotion2.02.94.4-1.72.1-1.6-1.7-2.12.0-1.71.7-1.71.31.7-1.7-0.7
Patch foraging indifference point 0 sec0.41.01.50.9-0.91.00.90.7-1.11.2-1.21.2-1.0-0.90.91.0
Patch foraging indifference point AUC0.51.22.31.4-1.31.41.50.7-0.80.9-0.90.9-1.1-0.20.6-1.5
Delay disc. indifference point, 0s delay0.30.31.0-0.70.8-0.6-0.7-0.90.3-0.30.3-0.20.2-0.1-0.21.0
Delay disc. indifference point, 16s delay0.00.10.20.3-0.00.40.3-0.0-0.20.2-0.20.2-0.4-0.00.2-0.0
Delay disc. indifference point, 2s delay0.30.30.8-0.60.8-0.4-0.5-0.90.6-0.60.6-0.70.20.6-0.5-0.2
Delay disc. indifference point, 24s delay0.20.31.20.3-0.40.20.30.4-0.60.5-0.50.5-0.4-0.80.61.1
Delay disc. indifference point, 4s delay0.90.93.70.4-0.50.50.40.1-1.01.0-1.00.9-0.8-1.31.01.9
Delay disc. indifference point, 8s delay0.10.21.1-0.60.4-0.6-0.7-0.60.1-0.10.1-0.10.4-0.3-0.21.0
Indifference point function ln k1.03.05.8-2.42.2-2.3-2.3-0.81.4-1.51.5-1.41.80.6-1.02.2
Indifference point function log k1.03.05.8-2.42.2-2.3-2.3-0.81.4-1.51.5-1.41.80.6-1.02.2
Patch foraging total patch changes 0 sec0.51.32.01.0-1.11.00.91.1-1.31.3-1.31.3-0.9-1.21.21.4
Patch foraging total patch changes 12 sec5.27.09.22.9-3.03.03.02.0-2.82.9-2.92.8-2.7-2.32.40.6
Patch foraging total patch changes 18 sec0.30.71.10.9-1.01.01.10.8-0.80.9-0.90.9-0.7-0.50.6-0.3
Patch foraging total patch changes 24 sec2.48.110.03.0-2.82.83.02.5-3.13.2-3.23.1-3.0-2.62.91.4
Patch foraging total patch changes 6 sec1.32.22.91.4-1.31.41.41.4-1.61.7-1.71.6-1.5-1.41.51.3
Patch foraging time to switch 0 sec0.10.20.70.6-0.20.80.7-0.3-0.20.3-0.30.3-0.90.10.2-0.4
Patch foraging water rate 0 sec0.10.40.9-0.80.6-1.0-0.90.30.5-0.50.5-0.51.00.3-0.40.5
Patch foraging water rate 12 sec0.41.73.8-1.71.4-1.9-1.9-0.21.0-1.21.2-1.21.70.4-0.81.0
Patch foraging water rate 18 sec0.30.64.1-0.80.6-1.0-0.90.6-0.1-0.20.2-0.20.5-0.60.22.0
Patch foraging water rate 24 sec0.81.12.2-1.51.1-1.4-1.3-0.40.9-1.01.0-0.91.30.5-0.80.6
Patch foraging water rate 6 sec0.71.12.7-1.51.1-1.6-1.5-0.00.7-0.80.8-0.71.40.1-0.61.2
Seeking ratio, delayed vs. immediate footshock0.00.00.10.2-0.10.10.10.1-0.30.2-0.20.1-0.3-0.30.20.3
Distance traveled before self-admin0.91.93.21.8-1.31.81.81.0-1.31.4-1.41.4-1.7-0.61.2-0.5
Distance traveled after self-admin0.30.51.00.9-0.90.60.91.0-0.60.6-0.60.6-0.5-0.40.6-0.4
Extensor digitorum longus weight5.923.729.15.4-4.95.05.23.7-5.35.2-5.25.2-5.3-4.75.02.6
Bone: elastic displacement0.20.20.5-0.70.2-0.6-0.70.10.3-0.40.4-0.40.7-0.1-0.20.6
Bone: elastic work1.41.93.41.0-1.41.11.01.6-1.41.2-1.21.3-1.1-1.81.51.9
Bone: endosteal estimation1.12.65.3-1.42.3-1.6-1.3-2.11.6-1.61.6-1.60.81.9-1.6-0.8
Bone: endosteal perimeter2.04.87.9-1.72.8-1.9-1.7-2.82.2-2.12.1-2.11.32.8-2.3-2.1
Epididymis fat weight0.73.55.5-1.42.3-1.6-1.4-2.21.8-1.91.9-2.01.12.3-1.9-2.2
Delta time in closed arm before/after self-admin2.52.47.90.8-1.20.90.80.8-1.61.5-1.51.5-1.3-2.31.62.8
Delta time in open arm before/after self-admin1.11.32.81.5-1.21.71.50.7-0.91.0-1.01.0-1.3-0.20.8-1.1
Diff in mean of infusions in LGA sessions1.73.14.01.7-2.01.71.91.6-1.82.0-2.01.9-1.6-1.81.70.8
Delay discount exponential model param0.10.21.0-0.10.1-0.2-0.10.20.4-0.50.5-0.40.50.6-0.4-1.0
Extinction: sum of active levers before priming2.53.85.22.2-1.92.02.31.7-2.02.1-2.12.1-2.1-1.62.00.6
Active lever presses in extinction session 62.12.13.91.8-1.62.02.01.3-1.21.3-1.31.3-1.6-0.71.2-0.8
Bone: final force1.22.03.11.7-1.21.71.71.2-1.51.4-1.41.4-1.8-1.01.40.3
Bone: final moment1.32.13.21.8-1.31.71.71.2-1.51.5-1.51.5-1.8-1.01.40.4
Food consumed during 24 hour testing period0.10.20.9-0.10.3-0.4-0.40.20.4-0.50.5-0.50.50.7-0.5-0.9
Glucose2.13.45.5-2.02.3-2.2-2.0-2.11.8-1.81.8-1.91.61.6-1.7-0.3
Heart weight0.20.31.9-0.60.9-0.8-0.5-0.50.1-0.30.3-0.2-0.0-0.30.01.4
Delay discount hyperbolic model param0.10.10.7-0.0-0.1-0.1-0.00.30.3-0.30.3-0.20.40.4-0.3-0.8
Intermittent access intake day 1-15 change0.63.67.7-1.51.6-1.5-1.3-1.72.0-1.91.9-1.91.72.3-1.9-2.8
Intermittent access intake escalation0.84.39.3-1.71.7-1.7-1.5-1.82.2-2.12.1-2.11.92.5-2.1-3.0
Intermittent access intake escalation 21.11.86.3-0.81.0-0.8-0.7-1.31.3-1.31.3-1.31.01.8-1.3-2.5
Intermitt. access day 1 inactive lever presses0.22.03.0-1.21.2-1.0-1.3-1.71.5-1.41.4-1.41.31.5-1.6-1.7
Intermitt. access day 15 inactive lever presses0.10.52.10.9-0.10.90.8-0.7-0.20.2-0.20.2-1.00.40.2-1.5
Intermitt. access escalation Index0.20.61.2-1.00.8-1.1-0.9-0.30.7-0.70.7-0.70.90.3-0.60.5
Intermittent access day 1 total infusions0.30.93.3-0.61.7-0.6-0.7-1.80.9-0.90.9-0.9-0.11.0-0.70.0
Intermittent access day 15 total infusions2.76.69.3-2.12.9-2.3-2.1-3.02.8-2.72.7-2.71.83.1-2.5-2.5
Intermittent access terminal intake (last 3 days)1.72.95.8-1.12.1-1.2-1.0-2.41.8-1.71.7-1.70.62.3-1.6-2.0
Intermittent access total infusions1.92.24.7-1.12.0-1.2-1.1-2.21.6-1.51.5-1.50.51.8-1.4-1.1
Intermittent access day 1 locomotion0.10.21.3-0.21.0-0.1-0.2-1.10.4-0.30.3-0.3-0.40.4-0.20.4
Intermittent access day 15 total locomotion0.31.03.0-0.41.2-0.3-0.4-1.71.1-0.90.9-0.9-0.01.5-0.9-1.3
Intermittent access total locomotion1.11.45.2-0.41.7-0.3-0.4-2.31.1-1.01.0-1.0-0.21.7-0.9-1.1
Intermittent access standard deviation0.31.82.9-1.11.2-1.2-1.1-1.21.5-1.51.5-1.51.11.5-1.3-1.7
Left kidney weight0.10.82.3-0.61.3-0.6-0.6-1.50.8-0.80.8-0.80.21.1-0.9-0.8
Right kidney weight0.10.61.9-0.40.9-0.5-0.4-1.40.6-0.60.6-0.70.20.9-0.7-1.1
Cocaine induced anxiety0.00.10.70.1-0.20.40.1-0.40.1-0.10.1-0.1-0.00.3-0.1-0.8
Post-drug Anxiety0.20.20.60.6-0.60.80.6-0.0-0.40.4-0.40.4-0.5-0.20.4-0.3
Baseline Anxiety0.50.81.90.6-0.70.50.61.0-0.90.9-0.90.9-0.7-1.20.91.4
Tail length0.31.72.61.1-1.51.00.91.4-1.51.5-1.51.6-0.8-1.61.31.0
Length with tail1.46.28.02.6-2.62.32.42.4-2.82.8-2.82.8-2.3-2.42.51.0
Length without tail1.89.712.03.2-3.23.03.22.9-3.43.5-3.53.3-3.1-3.13.21.5
Times rat made contact with spout0.40.51.00.3-0.70.30.21.0-0.80.7-0.70.7-0.2-0.90.61.0
Lifetime Intake1.21.53.1-1.01.7-1.1-1.0-1.71.3-1.31.3-1.30.41.3-1.0-0.5
Liver weight, left0.91.62.2-1.31.3-1.5-1.4-1.01.3-1.31.3-1.41.41.1-1.3-0.8
Liver weight, right0.91.73.0-1.61.7-1.7-1.7-0.81.1-1.21.2-1.21.40.8-1.10.4
Locomotor activity0.40.71.9-1.00.6-1.2-1.30.20.4-0.60.6-0.51.0-0.3-0.31.4
Locomotor testing distance0.40.93.4-1.20.8-1.2-1.30.20.4-0.70.7-0.61.0-0.4-0.31.8
Locomotor testing rearing0.31.02.0-1.41.0-1.3-1.40.30.7-1.01.0-1.01.20.2-0.61.0
Locomotion in novel chamber2.22.93.6-1.61.9-1.5-1.6-1.71.9-1.91.9-1.91.41.9-1.7-1.1
Locomotion in novel chamber post-restriction1.03.14.2-1.91.7-1.7-1.7-2.11.9-1.61.6-1.71.71.9-1.9-1.4
Fecal boli incidents, locomotor time 10.41.04.1-0.40.7-0.4-0.3-0.71.0-0.90.9-1.00.61.4-1.0-2.0
Change in fecal boli incidents, locomotor task0.70.71.4-1.21.0-1.1-1.2-1.10.5-0.50.5-0.50.90.1-0.51.2
Time >=10cm from walls, locomotor time 12.73.46.0-1.22.0-1.4-1.3-2.21.9-1.71.7-1.81.32.4-2.1-2.2
Bouts of movement, locomotor time 10.20.21.10.6-1.00.60.50.3-0.10.2-0.20.10.1-0.1-0.1-0.9
Total resting periods, locomotor time 10.20.21.20.5-0.80.60.50.30.00.1-0.10.00.10.1-0.1-1.1
Rest time, locomotor task time 11.32.12.6-1.51.3-1.5-1.5-0.81.5-1.51.5-1.51.61.5-1.4-1.4
Distance moved, locomotor task time 10.10.30.60.6-0.40.60.70.4-0.60.5-0.50.6-0.8-0.60.60.6
Vertical activity count, locomotor time 10.10.40.7-0.70.7-0.7-0.6-0.80.6-0.60.6-0.60.60.5-0.60.1
Time >=10cm from walls, locomotor time 20.20.63.20.00.3-0.1-0.1-0.40.7-0.60.6-0.70.41.2-0.8-1.8
Bouts of movement, locomotor time 20.41.21.91.3-1.31.21.21.4-1.11.0-1.01.1-1.1-1.01.10.2
Total resting periods, locomotor time 20.10.50.90.8-0.80.80.80.9-0.70.6-0.60.7-0.7-0.50.7-0.0
Rest time, locomotor task time 22.03.34.4-2.12.0-2.1-2.0-1.81.8-1.71.7-1.91.91.7-1.9-0.8
Distance moved, locomotor task time 20.40.61.40.9-1.00.90.81.2-0.60.5-0.50.6-0.6-0.70.80.0
Vertical activity count, locomotor time 20.10.10.6-0.0-0.4-0.0-0.10.5-0.20.1-0.10.30.3-0.60.30.8
Light reinforcement 10.00.10.4-0.10.1-0.3-0.10.60.1-0.30.3-0.20.40.3-0.1-0.6
Light reinforcement 20.51.26.1-0.30.9-0.3-0.1-1.01.0-1.01.0-0.90.41.7-1.0-2.5
Bone: marrow area1.23.06.0-1.62.4-1.7-1.5-2.21.8-1.71.7-1.71.02.0-1.7-0.8
Bone: maximum diameter0.10.31.50.50.20.50.5-0.6-0.00.1-0.10.1-0.50.6-0.2-1.2
Bone: maximum force1.42.85.62.2-1.32.12.21.1-1.71.6-1.61.6-2.4-1.01.60.1
Bone: maximum moment1.52.95.62.2-1.42.02.21.2-1.71.6-1.61.6-2.4-1.11.70.2
Mean time between licks in bursts0.21.34.50.7-0.80.40.51.3-1.20.8-0.80.8-0.7-1.71.42.1
Mean num. licks in bursts0.00.10.3-0.3-0.1-0.1-0.10.60.1-0.20.2-0.20.3-0.20.10.6
Cd content in liver0.91.01.8-0.91.1-0.8-0.9-1.31.1-0.80.8-0.80.91.3-1.2-0.7
Co content in liver0.40.51.4-1.00.4-0.9-0.90.30.5-0.50.5-0.51.2-0.0-0.40.6
Cu content in liver0.00.00.1-0.1-0.2-0.1-0.10.20.00.0-0.0-0.00.2-0.20.00.3
Fe content in liver0.00.00.1-0.20.2-0.1-0.2-0.30.10.0-0.00.00.0-0.1-0.00.2
K content in liver0.40.40.60.6-0.40.60.50.7-0.80.6-0.60.6-0.7-0.60.60.3
Mg content in liver0.20.21.00.00.10.1-0.10.3-0.50.5-0.50.5-0.3-0.50.41.0
Mn content in liver2.52.84.22.1-1.81.92.01.4-1.81.8-1.81.7-1.9-1.21.5-0.0
Na content in liver0.30.30.80.6-0.40.70.70.9-0.60.5-0.50.5-0.6-0.20.5-0.4
Rb content in liver1.92.24.0-1.91.7-1.8-2.0-1.41.3-1.41.4-1.31.70.9-1.40.1
Se content in liver0.10.10.70.30.00.20.3-0.30.1-0.00.0-0.0-0.30.4-0.2-0.8
Sr content in liver3.93.44.42.0-2.12.12.01.2-1.92.1-2.12.1-1.9-1.71.80.4
Zn content in liver2.73.24.31.8-1.81.91.71.0-1.92.1-2.12.1-1.9-1.71.71.1
Bone: minimum diameter0.81.53.2-0.81.8-1.0-0.9-1.71.2-1.21.2-1.20.51.7-1.2-1.1
Time in familiar zone, hab. session 10.10.10.70.3-0.10.20.20.8-0.20.1-0.10.2-0.3-0.10.40.4
Time in novel zone, hab. session 10.91.01.6-1.31.0-1.3-1.2-0.41.0-1.01.0-1.21.30.6-0.90.0
Total zone transitions, hab. session 10.30.51.10.5-0.60.50.40.1-0.71.0-1.01.0-0.5-0.70.60.3
Total locomotion distance, hab. session 10.10.21.4-0.30.5-0.1-0.4-1.20.20.1-0.10.1-0.00.4-0.5-0.3
Locomotion velocity, hab. session 10.20.20.60.3-0.10.50.2-0.8-0.40.7-0.70.7-0.5-0.10.0-0.2
Time in familiar zone, hab. session 20.40.42.5-0.40.2-0.7-0.41.60.3-0.70.7-0.50.80.20.00.4
Time in novel zone, hab. session 20.40.51.00.6-0.40.80.6-0.6-0.70.8-0.80.7-1.0-0.60.50.4
Total zone transitions, hab. session 21.72.13.11.3-1.11.31.21.2-1.61.6-1.61.7-1.5-1.51.51.6
Total locomotion distance, hab. session 20.20.30.80.3-0.10.40.2-0.1-0.60.7-0.70.8-0.6-0.50.40.9
Locomotion velocity, hab. session 20.10.10.30.10.10.30.0-0.5-0.30.5-0.50.6-0.5-0.10.10.5
Novel to familiar place preference ratio1.21.52.61.6-1.31.51.5-0.2-1.21.2-1.21.3-1.6-1.01.1-0.3
Novelty place preference0.70.81.61.3-1.01.11.1-0.4-0.80.9-0.90.9-1.2-0.70.8-0.4
Time in novel zone, NPP test0.80.91.71.3-1.11.11.2-0.3-0.90.9-0.90.9-1.3-0.80.9-0.2
Total zone transitions, NPP test1.42.03.31.1-1.31.41.10.7-1.51.7-1.71.8-1.4-1.51.41.6
Total locomotion distance, NPP test0.20.31.30.0-0.20.40.0-0.6-0.50.7-0.70.7-0.5-0.60.31.2
Locomotion velocity, NPP test0.20.20.7-0.1-0.10.3-0.1-0.7-0.30.6-0.60.6-0.3-0.50.10.9
Intraocular pressure0.10.20.5-0.30.1-0.4-0.4-0.20.5-0.50.5-0.40.60.5-0.5-0.7
Delta distance traveled before/after self-admin0.20.30.9-0.60.2-0.9-0.60.40.3-0.30.3-0.30.7-0.3-0.10.8
Delta ambulatory time before/after self-admin0.30.51.4-0.90.4-1.2-0.90.20.5-0.50.5-0.51.0-0.1-0.30.7
Parametrial fat weight2.04.78.1-1.72.7-1.9-1.8-2.82.2-2.12.1-2.01.42.6-2.3-2.1
Pavlov. Cond. lever latency0.70.91.5-1.20.7-1.1-1.1-1.00.9-0.90.9-1.01.20.6-0.9-0.2
Pavlov. Cond. magazine entry latency0.60.71.61.3-0.61.11.21.1-0.60.5-0.50.5-1.2-0.00.6-0.7
Pavlov. Cond. change in total contacts0.30.31.20.7-0.20.70.60.3-0.10.2-0.20.2-0.60.6-0.0-1.1
Pavlov. Cond. index score0.40.61.21.1-0.60.91.01.1-0.60.5-0.50.5-0.9-0.10.5-0.6
Pavlov. Cond. latency score0.40.51.11.0-0.50.90.91.0-0.60.5-0.50.5-0.9-0.20.6-0.3
Pavlov. Cond. lever contacts0.30.40.70.8-0.40.70.70.8-0.60.5-0.50.6-0.9-0.30.60.1
Pavlov. Cond. magazine entry number0.50.71.5-1.20.8-1.1-1.1-1.20.5-0.50.5-0.50.90.1-0.50.9
Pavlov. Cond. intertrial magazine entries0.10.10.90.2-0.30.40.1-0.50.3-0.30.3-0.30.10.3-0.2-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.31.1-0.61.01.01.0-0.60.5-0.50.6-1.0-0.00.5-0.7
Pavlov. Cond. response bias0.60.71.51.2-0.81.11.11.2-0.70.6-0.60.6-1.0-0.10.6-0.7
Pavlov. Cond. lever latency0.30.51.1-1.00.6-0.9-0.9-1.10.6-0.40.4-0.40.80.2-0.70.4
Pavlov. Cond. magazine entry latency3.55.07.92.7-2.52.82.72.7-2.11.9-1.91.9-2.4-1.62.20.2
Pavlov. Cond. change in total contacts0.51.32.81.6-1.11.61.61.7-0.80.7-0.70.7-1.3-0.10.8-1.2
Pavlov. Cond. index score1.62.54.62.1-1.62.12.12.0-1.31.1-1.11.1-1.9-0.71.4-0.6
Pavlov. Cond. latency score1.32.24.22.0-1.52.02.01.8-1.21.1-1.11.1-1.8-0.61.3-0.7
Pavlov. Cond. lever contacts0.30.41.50.9-0.60.80.91.2-0.40.2-0.20.2-0.7-0.00.6-0.6
Pavlov. Cond. magazine entry number5.77.411.9-3.33.0-3.4-3.3-3.02.6-2.42.4-2.43.01.9-2.6-0.1
Pavlov. Cond. intertrial magazine entries0.92.12.7-1.61.4-1.6-1.5-1.51.5-1.21.2-1.21.61.4-1.6-1.1
Pavlov. Cond. lever-magazine prob. diff.1.92.95.22.2-1.82.32.32.3-1.41.2-1.21.2-2.0-0.81.6-0.5
Pavlov. Cond. response bias1.52.14.01.9-1.51.81.82.0-1.31.1-1.11.1-1.6-0.91.5-0.2
Time in closed arm before self-admin0.20.41.8-0.10.5-0.3-0.1-0.30.6-0.60.6-0.60.21.0-0.5-1.4
Time in closed arm after self-admin0.60.71.3-1.00.9-1.2-1.1-0.60.7-0.90.9-0.90.80.4-0.70.3
Time in open arm before self-admin0.70.85.7-1.10.5-1.0-1.1-0.10.1-0.10.1-0.10.8-0.9-0.02.4
Time in open arm after self-admin0.80.91.20.7-1.00.90.80.9-0.91.1-1.11.1-0.7-1.10.91.1
Bone: periosteal estimation0.20.41.00.00.9-0.10.0-0.90.4-0.40.4-0.4-0.31.0-0.5-1.0
Bone: periosteal perimeter0.20.42.30.10.6-0.00.1-0.70.4-0.30.3-0.3-0.11.0-0.5-1.5
Bone: post-yield work0.40.72.2-0.11.3-0.30.0-1.00.8-0.70.7-0.7-0.31.5-0.7-1.1
Progressive ratio test 1 active lever presses0.30.61.1-0.60.9-0.6-0.6-1.00.9-0.80.8-0.80.40.8-0.7-0.4
Progressive ratio test 1 breakpoint0.30.61.1-0.60.9-0.6-0.6-1.11.0-0.80.8-0.80.40.9-0.7-0.5
Progressive ratio test 1 inactive lever presses0.20.41.10.9-0.60.80.70.3-0.60.6-0.60.6-1.0-0.50.70.0
Progressive ratio test 2 active lever presses1.41.93.2-0.91.6-1.0-1.0-1.61.6-1.41.4-1.40.71.8-1.3-1.7
Progressive ratio test 2 breakpoint1.41.83.1-0.91.5-1.0-0.9-1.61.5-1.41.4-1.40.61.8-1.2-1.6
Progressive ratio test 2 inactive lever presses0.61.74.0-0.71.4-0.6-0.8-2.01.4-1.31.3-1.30.51.7-1.2-1.8
Incentive Sensitization - Responses0.10.31.00.8-0.20.70.8-0.0-0.30.3-0.30.3-1.00.20.5-0.8
Incentive Sensitization - Breakpoint0.10.20.80.70.00.60.7-0.2-0.20.2-0.20.2-0.90.40.3-0.9
Sum of active levers in priming session hrs 5-60.90.95.81.1-1.01.11.20.4-0.20.3-0.30.3-0.50.50.0-2.4
Progressive ratio0.00.10.40.10.6-0.1-0.1-0.40.3-0.30.3-0.1-0.20.6-0.2-0.5
Food seeking constrained by brief footshock0.00.00.1-0.20.2-0.3-0.3-0.00.0-0.00.00.00.1-0.1-0.10.3
Seeking ratio, punishment vs. effort0.10.32.1-0.3-0.3-0.1-0.10.2-0.40.4-0.40.30.1-1.00.41.5
Retroperitoneal fat weight3.415.220.9-4.24.6-4.2-4.2-4.33.9-4.04.0-3.93.63.6-3.9-1.5
Reaction time number correct0.20.82.60.9-0.90.50.71.6-1.00.7-0.70.7-0.6-1.01.10.5
Reaction time mean minus median0.10.64.80.8-0.70.80.9-0.1-0.00.2-0.20.2-0.40.5-0.1-2.2
Reaction time mean minus median AUC0.00.32.70.4-0.60.40.50.30.1-0.00.0-0.00.10.4-0.1-1.6
Reaction time num false alarms0.30.54.1-0.7-0.0-0.5-0.60.50.0-0.00.00.00.5-0.80.32.0
Reaction time num false alarms AUC0.30.85.3-0.1-0.60.0-0.10.9-0.60.6-0.60.60.0-1.40.82.3
Reaction time trials correct on left0.20.82.60.9-0.90.50.71.6-1.00.7-0.70.7-0.6-1.01.10.5
Reaction time trials on left0.30.92.80.9-1.00.60.81.7-1.00.7-0.70.8-0.6-1.11.20.5
Reaction time mean0.20.42.1-0.20.10.10.10.00.8-0.60.6-0.60.31.0-0.5-1.4
Reaction time mean AUC0.30.62.8-0.20.3-0.1-0.1-0.00.9-0.80.8-0.80.51.2-0.7-1.7
Median of all reaction times0.10.20.7-0.20.20.10.10.20.6-0.40.4-0.50.20.8-0.3-0.8
Reaction time omissions0.20.40.80.5-0.90.70.80.8-0.40.5-0.50.5-0.4-0.30.5-0.6
Reaction time false alarm rate0.20.33.1-0.70.1-0.4-0.5-0.20.10.0-0.00.00.4-0.60.01.8
Reaction time premature initiation rate4.57.09.02.5-2.32.42.42.8-3.02.7-2.72.6-2.6-2.93.02.5
Reaction time premature initiations3.09.113.62.9-2.92.62.73.7-3.42.9-2.92.9-2.8-3.33.42.5
Std. dev. reaction times0.20.53.4-0.2-0.10.00.0-0.20.7-0.50.5-0.50.51.0-0.6-1.9
Reaction time trials completed0.30.92.80.9-1.00.60.81.7-1.00.7-0.70.8-0.6-1.11.20.5
Reaction time trials AUC0.20.82.50.8-0.80.50.71.6-1.00.6-0.60.7-0.6-1.01.10.7
Run reversals in cocaine runway, females1.11.26.00.6-0.40.60.40.6-1.11.1-1.11.1-1.0-1.41.12.4
Run reversals in cocaine runway, males0.30.30.6-0.70.5-0.7-0.7-0.70.5-0.30.3-0.50.80.4-0.6-0.2
Latency to leave start box in cocaine runway0.40.51.1-0.61.0-0.7-0.8-1.00.7-0.80.8-0.70.40.7-0.6-0.2
Latency to leave start box in cocaine runway, F0.00.00.10.20.00.20.0-0.2-0.20.1-0.10.0-0.3-0.10.20.0
Latency to leave start box in cocaine runway, M2.12.03.0-1.51.7-1.6-1.5-1.31.5-1.51.5-1.41.31.4-1.4-0.4
Std. dev. time between licks in bursts0.10.21.5-0.20.1-0.4-0.40.6-0.2-0.10.1-0.10.2-0.70.41.2
Total sessions with >9 infusions0.80.91.5-1.01.2-1.1-1.0-0.91.1-1.11.1-1.10.70.9-0.9-0.2
Short access day 1 total inactive lever presses0.10.10.8-0.10.5-0.2-0.2-0.20.3-0.10.1-0.1-0.20.00.00.9
Short access day 10 total inactive lever presses0.10.50.8-0.80.7-0.8-0.9-0.60.8-0.70.7-0.70.90.5-0.8-0.1
Short access day 1 total infusions0.81.52.6-1.41.6-1.4-1.3-1.11.3-1.31.3-1.30.91.0-1.2-0.1
Short access day 10 total infusions0.30.51.6-0.51.3-0.6-0.5-1.20.7-0.70.7-0.7-0.10.7-0.5-0.1
Short access total infusions0.50.71.9-0.91.4-1.0-0.9-1.10.9-0.80.8-0.80.30.5-0.60.4
Short access day 1 locomotion0.20.40.8-0.60.9-0.7-0.5-0.60.8-0.70.7-0.70.30.7-0.5-0.2
Short access day 10 total locomotion0.00.10.80.10.60.20.2-0.90.10.0-0.00.0-0.50.40.1-0.3
Short access total locomotion0.20.31.0-0.30.9-0.3-0.3-1.00.6-0.50.5-0.5-0.10.7-0.4-0.3
One hour access (0.3 mA shock)1.61.94.2-1.21.8-0.9-1.1-2.11.5-1.41.4-1.40.71.7-1.2-1.2
Compulsive drug intake1.21.84.40.9-1.50.80.92.1-1.41.3-1.31.3-0.6-1.81.31.5
One hour access (shock baseline)2.36.111.5-2.12.8-1.8-2.0-3.42.6-2.52.5-2.51.63.0-2.4-2.4
Social response proportion0.00.00.10.2-0.20.2-0.10.2-0.3-0.00.0-0.0-0.1-0.30.2-0.1
Social responses0.10.10.80.2-0.60.10.10.9-0.40.2-0.20.30.1-0.50.30.1
Social time0.00.10.2-0.2-0.4-0.1-0.20.1-0.30.3-0.30.30.3-0.50.00.1
Soleus weight2.57.39.9-3.02.9-2.9-3.1-2.42.8-2.82.8-2.73.02.4-2.7-0.7
Bone: stiffness0.30.51.31.2-0.50.91.10.4-0.50.5-0.50.5-1.00.20.4-1.1
Tibialis anterior weight8.228.134.15.8-5.75.85.83.6-5.65.8-5.85.8-5.6-4.95.12.0
Time to tail flick, vehicle, before self-admin0.10.10.40.30.10.40.4-0.4-0.10.2-0.20.2-0.60.00.10.0
Time to tail flick, vehicle, after self-admin0.20.51.20.5-0.30.50.50.3-0.70.7-0.70.8-0.8-0.80.61.1
Time to tail flick, test, before self-admin0.60.73.20.5-0.00.30.5-0.1-0.80.9-0.90.9-1.0-0.90.81.8
Time to tail flick, test, after self-admin0.10.10.60.2-0.00.20.2-0.10.1-0.10.1-0.2-0.00.4-0.2-0.8
Delta time to tail flick, vehicle, before/after SA0.40.40.80.4-0.60.50.40.5-0.70.7-0.70.7-0.5-0.80.60.9
Delta time to tail flick, test, before/after SA0.40.53.90.1-0.40.2-0.00.30.4-0.50.5-0.50.50.8-0.5-2.0
Tibia length0.92.65.12.2-1.52.32.00.2-1.41.7-1.71.7-1.9-0.30.9-1.6
Ambulatory time before self-admin0.51.52.81.6-1.21.71.60.8-1.01.1-1.11.1-1.4-0.31.0-0.9
Ambulatory time after self-admin0.10.10.50.6-0.30.30.60.5-0.10.2-0.20.2-0.30.20.3-0.7
Bone: tissue strength0.30.30.7-0.50.5-0.8-0.70.20.3-0.60.6-0.60.70.3-0.4-0.3
Total heroin consumption5.56.59.42.7-3.12.82.92.3-2.62.7-2.72.7-2.4-2.32.40.5
Bone: trabecular number0.71.42.41.4-0.81.21.50.8-1.21.2-1.21.1-1.6-0.81.20.8
Bone: trabecular spacing0.30.51.1-0.90.4-0.8-0.90.30.6-0.80.8-0.81.10.2-0.50.1
Bone: trabecular thickness0.30.30.9-0.30.6-0.5-0.2-0.50.7-0.60.6-0.60.40.9-0.6-0.8
Bone: trabecular tissue density3.66.38.9-3.02.4-2.7-2.8-2.12.7-2.52.5-2.43.02.3-2.7-1.5
Water consumed over 24 hours0.51.02.21.0-1.10.70.71.5-1.11.0-1.01.0-0.7-1.01.00.7
Number of responses in last shaping day0.30.41.10.3-0.60.40.30.7-0.60.6-0.60.6-0.5-1.00.51.0