Hub : Genes

Eef1g

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Eef1g 0.06 0.05 3.3e-05 0.03 0.02 0.03 0.03 4.5e-04 1.0e-03 2.0e-04 5.8e-04
2 Brain mRNA stability Eef1g 0.1 0.05 5.3e-12 0.11 0.12 0.12 0.13 1.3e-10 5.4e-11 4.7e-11 9.7e-12
3 IL mRNA stability Eef1g 0.18 0.11 2.7e-04 0.13 0.1 0.15 0.13 4.9e-04 2.5e-03 2.0e-04 5.9e-04
4 Adipose mRNA stability Eef1g 0.04 0.02 3.6e-05 0.03 0.02 0.01 0.02 3.6e-04 2.9e-03 5.0e-02 1.1e-03
5 Brain gene expression Eef1g 0.03 0.02 1.2e-03 0.02 0.02 0.02 0.02 2.7e-03 2.3e-03 8.9e-03 4.1e-03
6 PL mRNA stability Eef1g 0.03 0.02 1.3e-04 0.03 0.04 0.03 0.03 1.1e-04 4.3e-05 1.5e-04 1.4e-04
7 Liver intron excision ratio chr1_205860727_205861724 0.28 0.11 0.0e+00 0.16 0.15 0.15 0.16 6.0e-17 1.4e-16 2.4e-16 5.8e-17
8 Liver intron excision ratio chr1_205861529_205861724 0.31 0.11 0.0e+00 0.18 0.18 0.17 0.18 1.1e-19 2.2e-19 6.4e-19 1.2e-19
9 LHb mRNA stability Eef1g 0.24 0.14 1.6e-03 0.08 0.08 0.03 0.06 6.4e-03 5.4e-03 8.5e-02 1.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.30.70.4-0.60.80.5-0.5-0.8-0.4-0.5-0.5
Area under the delay curve0.10.10.1-0.1-0.0-0.1-0.0-0.2-0.3-0.3-0.3-0.3
BMI with tail2.16.810.81.9-2.62.52.5-2.7-3.3-2.6-2.4-2.7
BMI without tail1.12.23.01.2-1.40.91.4-1.6-1.7-1.7-1.4-1.7
Body weight3.615.117.53.7-4.03.13.8-4.1-4.2-4.1-3.9-4.1
Weight adjusted by age1.51.72.21.3-1.51.41.4-1.3-1.5-1.1-0.9-1.1
Bone surface1.52.74.31.4-1.92.11.7-1.5-2.0-1.4-1.4-1.3
Bone volume0.61.02.10.7-1.21.51.0-0.8-1.3-0.7-0.7-0.6
Breakpoint value in progressive ratio session1.92.13.11.8-1.51.71.6-1.4-1.3-1.1-1.2-1.2
Number of licking bursts0.00.00.0-0.1-0.1-0.2-0.10.10.0-0.1-0.10.1
Context. condit. distance diff. score0.20.30.8-0.90.8-0.5-0.60.40.30.30.10.2
Locomotion velocity, session 10.10.10.3-0.00.2-0.00.1-0.3-0.2-0.4-0.5-0.5
Locomotion distance, session 10.70.91.80.5-0.60.70.9-1.0-1.0-1.2-1.3-1.2
Locomotion velocity, session 23.03.53.91.7-1.71.92.0-1.9-1.9-1.8-2.0-1.8
Locomotion distance, session 20.30.40.90.4-0.30.30.6-0.7-0.6-0.8-1.0-0.8
Locomotion velocity, session 30.40.40.80.1-0.50.40.5-0.6-0.9-0.8-0.9-0.7
Locomotion distance, session 30.10.10.30.3-0.2-0.10.1-0.2-0.2-0.5-0.4-0.4
Stereotopy head waving bouts, day 30.10.20.9-0.90.60.1-0.10.1-0.20.1-0.40.1
Stereotopy head waving duration, day 30.10.10.7-0.80.6-0.1-0.20.1-0.00.1-0.40.0
Locomotion velocity, session 70.00.00.3-0.50.30.1-0.10.1-0.10.1-0.10.1
Locomotion distance, session 70.10.10.3-0.50.5-0.5-0.40.10.1-0.0-0.1-0.1
Stereotopy head waving bouts, day 70.20.20.8-0.0-0.20.90.5-0.3-0.5-0.0-0.5-0.0
Stereotopy head waving duration, day 71.92.32.91.4-1.51.71.6-1.5-1.7-1.3-1.5-1.4
Locomotion velocity, session 80.10.10.3-0.10.4-0.2-0.0-0.20.1-0.3-0.5-0.3
Locomotion distance, session 80.10.20.8-0.90.7-0.3-0.40.30.10.3-0.10.2
Degree of sensitization distance0.10.10.5-0.70.4-0.1-0.30.1-0.20.20.00.1
Degree of sensitization stereotypy0.91.02.40.8-1.01.61.2-0.9-1.1-0.6-0.8-0.6
Conditioned locomotion0.60.70.80.8-0.80.80.8-0.9-0.9-0.8-0.9-0.9
Cocaine response after cond. corrected0.50.61.3-0.91.1-1.1-0.80.60.70.40.20.3
Cocaine response after cond. not corrected0.40.40.9-0.80.9-0.8-0.60.60.60.50.50.4
Cocaine response before conditioning0.30.41.80.6-0.81.40.7-0.2-0.4-0.00.5-0.1
Saline control response2.53.34.22.0-1.90.91.9-1.9-1.7-2.0-1.9-2.0
Bone: connectivity density1.52.43.41.3-1.61.71.5-1.6-1.8-1.4-1.4-1.6
Bone: cortical apparent density0.50.71.00.9-0.71.00.9-0.8-0.6-0.8-1.0-0.8
Bone: cortical area0.71.11.61.0-1.31.21.2-0.9-1.1-1.0-0.9-0.8
Bone: cortical porosity0.00.00.1-0.10.30.0-0.10.10.30.3-0.10.2
Bone: cortical porosity0.10.10.20.3-0.10.20.2-0.3-0.0-0.1-0.4-0.2
Bone: cortical thickness3.35.46.72.6-2.41.82.4-2.3-2.0-2.6-2.4-2.4
Bone: cortical thickness0.60.71.11.0-0.80.40.8-0.8-0.5-1.1-0.9-1.0
Bone: cortical tissue density0.70.91.31.0-0.81.11.0-0.9-0.7-0.9-1.1-0.9
Condit. Reinf. active minus inactive responses1.11.21.51.1-1.11.21.2-1.1-1.1-1.0-1.1-1.0
Condit. Reinf. active-inactive response ratio0.40.50.70.9-0.60.60.7-0.7-0.6-0.7-0.8-0.7
Condit. Reinf. active responses0.91.12.40.8-1.01.51.2-0.9-1.2-0.7-0.9-0.8
Condit. Reinf. inactive responses0.10.10.2-0.4-0.10.50.00.2-0.20.40.50.4
Incentive salience index mean1.31.62.01.1-1.31.41.3-1.2-1.4-1.2-1.1-1.2
Condit. Reinf. lever presses0.70.91.30.7-1.01.11.0-0.9-1.1-0.9-0.8-0.9
Condit. Reinf. active minus inactive responses0.40.51.0-0.60.5-0.1-0.50.80.71.00.81.0
Condit. Reinf. active-inactive response ratio1.01.02.1-1.20.80.0-0.61.00.61.41.11.4
Condit. Reinf. active responses0.00.00.00.1-0.10.10.10.10.10.00.00.2
Condit. Reinf. inactive responses0.20.30.80.7-0.4-0.20.3-0.4-0.1-0.9-0.5-0.7
Condit. Reinf. lever presses0.71.01.91.1-1.21.41.1-0.8-1.0-0.8-0.5-0.7
Condit. Reinf. lever reinforcers received0.10.10.30.4-0.40.50.4-0.2-0.2-0.2-0.1-0.1
Conditioned reinforcement - actives2.42.43.5-1.51.5-0.8-1.31.61.51.91.81.9
Conditioned reinforcement - inactives1.01.11.8-1.31.0-0.2-0.81.10.81.31.31.3
Conditioned locomotion2.02.43.8-1.91.7-0.8-1.51.61.21.71.61.6
Patch foraging indifference point 0 sec0.61.01.30.9-0.91.11.0-1.0-1.0-1.0-1.1-1.0
Patch foraging indifference point AUC2.02.44.31.7-1.82.11.6-1.4-1.5-1.1-1.2-1.0
Delay disc. indifference point, 0s delay0.20.20.7-0.80.6-0.8-0.50.20.10.00.1-0.0
Delay disc. indifference point, 16s delay0.10.10.20.1-0.30.40.2-0.2-0.5-0.2-0.2-0.2
Delay disc. indifference point, 2s delay0.20.20.5-0.70.5-0.3-0.50.40.20.40.50.4
Delay disc. indifference point, 24s delay0.20.20.40.4-0.2-0.10.2-0.4-0.3-0.6-0.5-0.6
Delay disc. indifference point, 4s delay0.50.61.10.4-0.4-0.00.5-0.8-0.7-1.0-1.1-1.0
Delay disc. indifference point, 8s delay0.30.31.0-0.50.7-1.0-0.70.30.50.10.00.1
Indifference point function ln k3.04.17.3-2.22.5-2.7-2.31.92.01.31.51.3
Indifference point function log k3.04.17.3-2.22.5-2.7-2.31.92.01.31.51.3
Patch foraging total patch changes 0 sec0.61.01.51.0-0.80.80.9-1.1-0.9-1.1-1.2-1.1
Patch foraging total patch changes 12 sec6.88.911.23.1-3.03.33.1-3.0-2.9-2.6-3.0-2.7
Patch foraging total patch changes 18 sec0.50.71.01.0-0.91.00.9-0.8-0.7-0.6-0.8-0.6
Patch foraging total patch changes 24 sec7.79.411.03.1-3.12.53.0-3.2-3.2-3.1-3.3-3.1
Patch foraging total patch changes 6 sec1.32.02.31.4-1.31.41.3-1.4-1.4-1.3-1.5-1.4
Patch foraging time to switch 0 sec0.40.62.00.3-0.71.40.9-0.6-1.0-0.3-0.4-0.4
Patch foraging water rate 0 sec0.40.61.1-0.50.9-1.1-0.90.81.00.50.60.6
Patch foraging water rate 12 sec1.62.47.0-1.21.7-2.6-1.81.41.70.81.00.9
Patch foraging water rate 18 sec0.70.94.1-0.71.0-2.0-1.10.60.80.00.20.1
Patch foraging water rate 24 sec1.11.62.9-1.11.4-1.7-1.41.21.40.91.00.9
Patch foraging water rate 6 sec1.11.64.9-1.01.4-2.2-1.41.11.40.60.70.7
Seeking ratio, delayed vs. immediate footshock0.00.00.00.1-0.10.1-0.0-0.1-0.1-0.2-0.2-0.2
Distance traveled before self-admin2.22.33.41.6-1.81.81.6-1.4-1.5-1.3-1.3-1.2
Distance traveled after self-admin0.20.20.60.8-0.70.40.3-0.4-0.4-0.4-0.3-0.3
Extensor digitorum longus weight6.726.528.75.1-5.44.55.0-5.2-5.3-5.3-5.3-5.1
Bone: elastic displacement0.40.51.1-0.50.8-1.0-0.80.60.90.50.40.4
Bone: elastic work0.91.21.81.2-0.90.61.0-1.1-0.9-1.3-1.3-1.3
Bone: endosteal estimation1.22.74.6-2.21.5-1.1-1.61.71.01.71.81.8
Bone: endosteal perimeter2.04.26.5-2.51.8-1.2-1.92.21.42.32.32.4
Epididymis fat weight0.40.91.4-1.10.7-1.2-1.00.90.60.71.20.8
Delta time in closed arm before/after self-admin2.12.03.81.1-1.00.31.0-1.6-1.4-1.8-1.8-1.9
Delta time in open arm before/after self-admin1.51.53.71.1-1.31.91.5-1.0-1.2-0.7-0.9-0.7
Diff in mean of infusions in LGA sessions1.82.02.91.7-1.41.31.5-1.4-1.2-1.3-1.5-1.3
Delay discount exponential model param0.00.10.10.10.00.10.00.20.30.30.30.3
Extinction: sum of active levers before priming3.93.94.62.1-2.11.92.0-2.0-2.0-1.8-2.0-1.8
Active lever presses in extinction session 62.62.54.81.7-1.72.21.8-1.5-1.5-1.1-1.3-1.2
Bone: final force2.03.23.91.6-1.91.91.9-1.7-2.0-1.7-1.7-1.6
Bone: final moment1.93.03.71.6-1.91.91.8-1.7-1.9-1.6-1.6-1.6
Food consumed during 24 hour testing period0.10.20.3-0.10.1-0.5-0.40.50.40.40.50.5
Glucose3.14.65.6-2.42.0-2.1-2.32.21.92.12.22.1
Heart weight0.81.22.6-1.31.2-1.6-1.30.90.80.80.90.7
Delay discount hyperbolic model param0.10.10.10.10.00.1-0.00.30.30.30.40.4
Intermittent access intake day 1-15 change1.61.62.6-0.91.0-0.6-1.11.31.31.51.51.6
Intermittent access intake escalation0.90.91.6-0.70.7-0.3-0.81.11.11.21.21.3
Intermittent access intake escalation 20.10.10.30.1-0.10.50.10.20.20.40.40.5
Intermitt. access day 1 inactive lever presses1.92.03.3-1.81.5-0.8-1.31.51.31.51.41.5
Intermitt. access day 15 inactive lever presses0.10.10.5-0.3-0.30.70.1-0.0-0.50.00.10.2
Intermitt. access escalation Index0.20.20.6-0.50.4-0.8-0.60.20.30.10.1-0.0
Intermittent access day 1 total infusions0.80.92.8-1.71.0-0.2-0.70.80.21.01.00.8
Intermittent access day 15 total infusions3.53.95.6-2.41.9-1.0-1.72.11.62.32.32.2
Intermittent access terminal intake (last 3 days)0.80.81.7-1.30.70.3-0.40.90.31.21.21.1
Intermittent access total infusions1.01.12.4-1.51.0-0.1-0.71.00.51.21.31.2
Intermittent access day 1 locomotion0.20.21.1-1.10.50.2-0.10.1-0.40.20.2-0.0
Intermittent access day 15 total locomotion0.20.30.7-0.90.40.5-0.20.4-0.10.70.60.5
Intermittent access total locomotion0.30.41.3-1.20.30.80.00.3-0.50.60.50.4
Intermittent access standard deviation1.51.62.3-1.11.2-0.6-1.01.31.31.51.51.5
Left kidney weight0.00.00.1-0.1-0.30.10.1-0.1-0.4-0.10.0-0.0
Right kidney weight0.10.20.50.1-0.70.70.4-0.3-0.7-0.2-0.3-0.1
Cocaine induced anxiety0.30.31.00.6-0.51.00.6-0.4-0.5-0.3-0.3-0.3
Post-drug Anxiety0.60.71.70.8-0.91.30.9-0.7-0.8-0.6-0.6-0.4
Baseline Anxiety1.11.21.41.2-1.10.61.0-1.1-1.0-1.2-1.2-1.2
Tail length1.03.04.22.0-1.70.81.6-1.8-1.4-2.0-1.8-1.9
Length with tail2.48.610.13.1-3.02.22.8-3.0-2.8-3.2-3.1-3.0
Length without tail1.94.24.92.1-2.21.82.0-2.0-2.1-2.1-2.2-1.9
Times rat made contact with spout0.20.20.50.7-0.3-0.30.4-0.4-0.2-0.7-0.7-0.6
Lifetime Intake0.81.02.3-1.51.0-0.3-0.70.90.51.11.21.0
Liver weight, left0.30.50.9-0.50.8-1.0-0.90.70.80.60.70.6
Liver weight, right0.00.00.20.0-0.0-0.4-0.20.0-0.1-0.3-0.1-0.2
Locomotor activity0.61.02.9-0.61.2-1.7-1.20.81.20.40.60.4
Locomotor testing distance0.71.13.3-0.81.3-1.8-1.30.71.10.30.60.2
Locomotor testing rearing0.91.43.0-1.01.3-1.7-1.31.11.30.71.00.7
Locomotion in novel chamber2.53.14.8-2.01.7-0.8-1.51.81.42.22.12.0
Locomotion in novel chamber post-restriction2.53.14.0-2.01.9-1.5-1.71.71.71.81.41.8
Fecal boli incidents, locomotor time 10.40.51.1-0.60.30.1-0.40.80.51.00.91.0
Change in fecal boli incidents, locomotor task0.50.51.6-0.80.9-1.2-0.90.50.60.10.10.2
Time >=10cm from walls, locomotor time 12.72.74.2-2.11.4-0.8-1.51.71.31.91.72.0
Bouts of movement, locomotor time 10.20.20.50.7-0.30.60.6-0.30.10.0-0.2-0.1
Total resting periods, locomotor time 10.20.20.50.6-0.40.70.6-0.3-0.00.0-0.1-0.0
Rest time, locomotor task time 11.41.62.0-0.91.2-1.4-1.41.31.41.11.11.3
Distance moved, locomotor task time 10.30.30.40.3-0.50.60.6-0.5-0.7-0.5-0.4-0.6
Vertical activity count, locomotor time 10.60.61.0-1.00.8-0.7-0.80.80.80.80.80.7
Time >=10cm from walls, locomotor time 20.20.30.6-0.30.20.1-0.20.50.40.80.60.8
Bouts of movement, locomotor time 21.41.52.11.4-1.31.11.3-1.2-1.1-1.2-1.1-1.2
Total resting periods, locomotor time 20.60.71.01.0-0.90.80.8-0.8-0.8-0.8-0.7-0.8
Rest time, locomotor task time 23.43.95.2-1.92.1-2.0-2.32.02.01.91.71.9
Distance moved, locomotor task time 20.50.61.00.9-0.80.91.0-0.7-0.6-0.6-0.4-0.7
Vertical activity count, locomotor time 20.00.10.20.20.2-0.4-0.1-0.00.4-0.2-0.0-0.2
Light reinforcement 10.10.10.3-0.20.3-0.3-0.30.40.60.30.40.4
Light reinforcement 20.40.61.3-0.80.20.3-0.40.80.31.01.01.1
Bone: marrow area1.43.05.1-2.31.6-1.3-1.81.81.11.81.91.9
Bone: maximum diameter0.10.20.70.1-0.50.90.6-0.2-0.6-0.1-0.10.1
Bone: maximum force2.34.06.01.6-2.22.32.1-1.9-2.5-1.7-1.7-1.7
Bone: maximum moment2.13.75.61.6-2.22.22.0-1.8-2.4-1.7-1.6-1.7
Mean time between licks in bursts0.81.22.41.2-0.8-0.40.7-1.2-0.9-1.5-1.0-1.6
Mean num. licks in bursts0.00.00.10.20.2-0.3-0.10.00.20.0-0.0-0.1
Cd content in liver1.31.51.9-1.21.2-1.1-1.11.21.11.41.21.3
Co content in liver1.72.03.6-0.91.5-1.9-1.51.31.81.01.11.0
Cu content in liver0.30.30.70.7-0.40.00.4-0.7-0.4-0.7-0.8-0.8
Fe content in liver0.00.00.1-0.20.10.40.10.0-0.00.30.10.2
K content in liver1.01.01.70.7-1.11.31.0-0.9-1.2-1.0-0.9-0.8
Mg content in liver0.40.40.70.2-0.60.80.5-0.5-0.9-0.6-0.7-0.5
Mn content in liver2.12.43.91.6-1.72.01.5-1.5-1.6-1.4-1.3-1.3
Na content in liver0.60.61.40.6-0.91.20.9-0.6-0.8-0.6-0.6-0.5
Rb content in liver1.41.83.1-1.51.4-1.8-1.51.31.31.01.11.1
Se content in liver0.20.31.60.2-0.61.30.5-0.3-0.60.0-0.00.0
Sr content in liver6.05.56.32.4-2.42.22.5-2.4-2.3-2.3-2.3-2.2
Zn content in liver4.34.85.92.0-2.22.42.4-2.2-2.3-1.9-2.2-1.9
Bone: minimum diameter0.61.22.2-1.50.9-0.7-1.01.20.51.11.31.3
Time in familiar zone, hab. session 10.10.10.10.3-0.30.20.2-0.2-0.3-0.10.2-0.3
Time in novel zone, hab. session 11.31.32.1-1.11.2-1.4-1.31.11.30.90.91.0
Total zone transitions, hab. session 10.30.51.30.5-0.50.50.7-0.7-0.6-0.7-1.1-0.7
Total locomotion distance, hab. session 10.10.10.4-0.60.40.2-0.10.2-0.00.3-0.20.3
Locomotion velocity, hab. session 10.20.20.60.0-0.20.70.5-0.4-0.5-0.3-0.8-0.2
Time in familiar zone, hab. session 20.40.41.3-0.00.4-1.1-0.80.60.90.30.80.3
Time in novel zone, hab. session 20.60.61.00.4-0.61.00.8-0.8-1.0-0.6-0.8-0.7
Total zone transitions, hab. session 21.62.12.81.3-1.31.11.4-1.5-1.5-1.7-1.6-1.6
Total locomotion distance, hab. session 20.20.20.50.1-0.30.40.4-0.4-0.5-0.6-0.7-0.5
Locomotion velocity, hab. session 20.10.10.3-0.1-0.10.40.3-0.2-0.4-0.3-0.6-0.2
Novel to familiar place preference ratio1.92.02.61.3-1.61.61.5-1.5-1.6-1.2-1.2-1.2
Novelty place preference1.11.11.51.0-1.21.21.1-1.1-1.2-0.9-0.8-0.9
Time in novel zone, NPP test1.21.21.71.0-1.21.21.1-1.2-1.3-1.0-0.9-1.0
Total zone transitions, NPP test1.42.13.01.2-1.21.31.5-1.5-1.4-1.5-1.7-1.5
Total locomotion distance, NPP test0.10.20.50.0-0.00.40.5-0.4-0.4-0.5-0.7-0.5
Locomotion velocity, NPP test0.10.10.5-0.10.10.40.4-0.3-0.2-0.3-0.7-0.3
Intraocular pressure0.10.20.3-0.10.2-0.4-0.40.40.50.40.50.5
Delta distance traveled before/after self-admin0.60.71.7-0.60.8-1.3-1.10.80.90.60.60.6
Delta ambulatory time before/after self-admin1.01.12.6-0.71.1-1.6-1.30.91.20.70.80.7
Parametrial fat weight1.52.94.4-2.11.6-1.3-1.71.81.31.81.71.8
Pavlov. Cond. lever latency1.11.42.3-1.01.2-1.5-1.31.11.41.01.01.1
Pavlov. Cond. magazine entry latency0.81.12.60.9-1.21.61.2-0.9-1.3-0.6-0.5-0.7
Pavlov. Cond. change in total contacts0.30.42.00.3-0.51.40.7-0.3-0.60.20.00.0
Pavlov. Cond. index score0.50.71.80.8-0.91.31.0-0.7-0.9-0.4-0.4-0.5
Pavlov. Cond. latency score0.40.51.30.7-0.81.10.9-0.6-0.8-0.4-0.4-0.5
Pavlov. Cond. lever contacts0.20.20.60.4-0.50.70.5-0.4-0.6-0.3-0.3-0.4
Pavlov. Cond. magazine entry number0.60.82.5-0.91.0-1.6-1.10.70.80.30.30.4
Pavlov. Cond. intertrial magazine entries0.10.10.40.1-0.10.60.3-0.10.00.20.00.2
Pavlov. Cond. lever-magazine prob. diff.0.70.82.20.9-1.01.51.1-0.8-1.0-0.5-0.5-0.6
Pavlov. Cond. response bias0.60.72.10.8-1.01.51.0-0.7-0.9-0.4-0.3-0.5
Pavlov. Cond. lever latency0.40.51.4-0.70.9-1.2-0.80.60.80.50.20.5
Pavlov. Cond. magazine entry latency4.55.28.02.4-2.42.82.6-2.2-2.2-1.9-1.5-2.0
Pavlov. Cond. change in total contacts1.21.63.81.4-1.61.91.5-1.0-1.3-0.8-0.5-0.7
Pavlov. Cond. index score2.53.26.51.8-2.02.62.0-1.6-1.8-1.3-0.9-1.4
Pavlov. Cond. latency score2.32.86.41.7-1.92.51.9-1.5-1.7-1.2-0.8-1.3
Pavlov. Cond. lever contacts0.40.51.70.8-0.81.30.8-0.5-0.6-0.40.0-0.4
Pavlov. Cond. magazine entry number7.08.611.6-3.13.2-3.4-3.32.93.02.52.12.6
Pavlov. Cond. intertrial magazine entries1.72.32.5-1.61.6-1.6-1.51.51.61.41.11.6
Pavlov. Cond. lever-magazine prob. diff.2.83.66.72.0-2.22.62.2-1.7-1.9-1.4-1.0-1.5
Pavlov. Cond. response bias1.52.03.61.6-1.71.91.6-1.3-1.4-1.1-0.7-1.2
Time in closed arm before self-admin0.10.10.3-0.2-0.00.2-0.10.30.10.40.50.5
Time in closed arm after self-admin0.50.51.3-0.70.8-1.1-0.90.60.60.40.60.4
Time in open arm before self-admin0.80.93.3-0.71.1-1.8-1.10.61.00.20.20.1
Time in open arm after self-admin0.10.10.20.5-0.10.20.3-0.20.1-0.1-0.4-0.2
Bone: periosteal estimation0.10.20.4-0.70.00.2-0.10.4-0.20.40.50.6
Bone: periosteal perimeter0.10.10.3-0.4-0.00.3-0.00.4-0.10.30.40.6
Bone: post-yield work0.50.61.3-1.10.30.4-0.50.7-0.11.21.11.0
Progressive ratio test 1 active lever presses2.02.12.9-1.71.6-0.9-1.11.41.31.71.61.5
Progressive ratio test 1 breakpoint2.32.43.2-1.81.7-0.9-1.21.51.41.81.71.6
Progressive ratio test 1 inactive lever presses0.10.10.2-0.1-0.10.30.4-0.4-0.4-0.3-0.3-0.5
Progressive ratio test 2 active lever presses1.81.93.1-1.81.4-0.5-1.01.41.01.71.61.6
Progressive ratio test 2 breakpoint2.93.24.4-2.11.8-1.0-1.51.81.52.12.02.0
Progressive ratio test 2 inactive lever presses0.70.82.0-1.40.90.1-0.50.80.41.11.11.0
Incentive Sensitization - Responses0.10.10.4-0.1-0.30.60.3-0.2-0.50.00.00.0
Incentive Sensitization - Breakpoint0.10.10.3-0.2-0.20.60.2-0.0-0.40.20.20.1
Sum of active levers in priming session hrs 5-61.00.92.81.2-1.21.71.2-0.7-0.7-0.3-0.5-0.2
Progressive ratio0.00.00.0-0.1-0.10.1-0.00.1-0.10.10.20.2
Food seeking constrained by brief footshock0.10.10.5-0.30.4-0.7-0.50.20.3-0.1-0.00.0
Seeking ratio, punishment vs. effort0.10.10.4-0.10.4-0.6-0.2-0.10.2-0.2-0.3-0.3
Retroperitoneal fat weight2.58.110.4-3.22.9-3.0-3.12.82.52.72.82.7
Reaction time number correct0.60.81.51.2-1.0-0.30.6-0.9-0.7-1.2-0.9-1.0
Reaction time mean minus median0.20.31.30.6-0.71.10.6-0.3-0.40.30.00.1
Reaction time mean minus median AUC0.10.10.30.6-0.40.40.2-0.1-0.00.20.10.2
Reaction time num false alarms0.10.20.6-0.10.7-0.8-0.40.20.6-0.10.1-0.2
Reaction time num false alarms AUC0.20.20.50.50.2-0.40.1-0.40.1-0.6-0.6-0.7
Reaction time trials correct on left0.60.81.51.2-1.0-0.30.6-0.9-0.7-1.2-0.9-1.0
Reaction time trials on left0.60.91.61.3-1.0-0.30.6-0.9-0.7-1.3-0.9-1.1
Reaction time mean0.20.30.8-0.10.10.7-0.00.40.30.90.70.6
Reaction time mean AUC0.30.41.0-0.20.20.5-0.20.50.41.00.90.8
Median of all reaction times0.10.10.60.0-0.10.80.20.1-0.00.50.40.3
Reaction time omissions0.10.10.30.6-0.20.40.2-0.30.0-0.0-0.2-0.2
Reaction time false alarm rate0.10.10.5-0.40.7-0.2-0.30.20.50.20.1-0.0
Reaction time premature initiation rate4.35.88.02.4-2.41.22.3-2.5-2.4-2.8-2.5-2.8
Reaction time premature initiations5.57.811.23.1-2.81.12.5-2.9-2.6-3.4-2.9-3.2
Std. dev. reaction times0.20.30.9-0.00.20.4-0.20.50.51.00.70.8
Reaction time trials completed0.60.91.61.3-1.0-0.30.6-0.9-0.7-1.3-0.9-1.1
Reaction time trials AUC0.50.71.31.1-0.9-0.40.5-0.8-0.6-1.1-0.8-1.0
Run reversals in cocaine runway, females1.21.12.10.7-0.70.30.8-1.1-1.1-1.3-1.4-1.4
Run reversals in cocaine runway, males0.50.50.7-0.60.8-0.8-0.80.70.90.50.40.7
Latency to leave start box in cocaine runway0.30.30.5-0.70.6-0.4-0.60.60.30.60.60.5
Latency to leave start box in cocaine runway, F0.00.00.10.1-0.10.20.1-0.1-0.2-0.0-0.0-0.1
Latency to leave start box in cocaine runway, M3.43.23.6-1.91.9-1.8-1.81.81.71.81.81.7
Std. dev. time between licks in bursts0.20.21.1-0.10.4-1.1-0.50.20.4-0.10.3-0.2
Total sessions with >9 infusions1.51.73.0-1.71.4-1.2-1.31.20.91.31.41.1
Short access day 1 total inactive lever presses0.80.91.9-1.41.1-0.8-0.80.90.60.90.90.7
Short access day 10 total inactive lever presses2.22.43.1-1.81.7-1.7-1.81.51.61.31.31.2
Short access day 1 total infusions0.80.81.7-1.31.0-0.8-0.80.90.70.91.00.7
Short access day 10 total infusions0.20.31.2-1.10.5-0.1-0.30.4-0.10.40.50.3
Short access total infusions0.30.41.3-1.10.8-0.3-0.50.50.20.60.60.3
Short access day 1 locomotion0.10.10.4-0.3-0.10.20.2-0.3-0.7-0.3-0.2-0.4
Short access day 10 total locomotion0.10.10.2-0.4-0.00.40.1-0.1-0.5-0.1-0.2-0.2
Short access total locomotion0.30.30.8-0.2-0.30.60.5-0.5-0.9-0.4-0.5-0.6
One hour access (0.3 mA shock)3.94.66.8-2.62.2-1.3-1.92.21.92.32.32.3
Compulsive drug intake1.41.52.51.5-1.0-0.10.7-1.3-0.7-1.6-1.4-1.6
One hour access (shock baseline)5.46.38.9-2.92.4-1.0-2.02.72.22.92.83.0
Social response proportion0.10.20.30.4-0.40.50.3-0.4-0.4-0.5-0.1-0.5
Social responses0.10.10.30.6-0.20.20.1-0.30.0-0.4-0.3-0.4
Social time0.10.10.50.20.1-0.7-0.2-0.10.2-0.4-0.3-0.2
Soleus weight2.67.78.7-2.93.0-2.7-2.82.92.82.62.62.7
Bone: stiffness0.61.02.00.9-1.21.41.1-0.8-1.2-0.7-0.6-0.6
Tibialis anterior weight10.435.437.86.0-6.15.76.1-6.0-6.0-5.8-6.1-5.7
Time to tail flick, vehicle, before self-admin0.50.51.00.3-0.71.00.8-0.7-1.0-0.5-0.5-0.6
Time to tail flick, vehicle, after self-admin0.50.60.90.5-0.60.30.6-0.8-0.8-1.0-0.9-1.0
Time to tail flick, test, before self-admin0.40.40.80.2-0.5-0.10.3-0.6-0.8-0.9-0.9-0.8
Time to tail flick, test, after self-admin0.10.10.2-0.20.2-0.4-0.30.30.40.20.30.3
Delta time to tail flick, vehicle, before/after SA0.00.00.10.10.0-0.2-0.0-0.2-0.0-0.3-0.3-0.3
Delta time to tail flick, test, before/after SA0.10.10.30.20.10.2-0.00.30.50.50.50.5
Tibia length1.33.88.71.6-2.13.02.3-1.7-2.1-1.2-1.5-1.2
Ambulatory time before self-admin1.81.94.11.3-1.62.01.6-1.2-1.4-1.0-1.0-0.9
Ambulatory time after self-admin0.10.10.40.5-0.60.60.3-0.2-0.4-0.1-0.1-0.1
Bone: tissue strength0.30.30.6-0.30.3-0.8-0.70.60.60.40.70.5
Total heroin consumption3.84.56.42.5-2.22.02.2-2.1-1.8-2.0-2.1-2.0
Bone: trabecular number0.60.91.60.7-1.11.20.9-0.9-1.3-0.7-0.8-0.9
Bone: trabecular spacing0.30.30.8-0.20.5-0.9-0.60.50.90.20.60.3
Bone: trabecular thickness0.40.50.9-0.70.5-0.2-0.60.70.50.90.80.9
Bone: trabecular tissue density4.15.77.1-2.42.7-2.1-2.42.42.62.42.22.4
Water consumed over 24 hours0.50.51.11.0-0.80.20.6-0.7-0.5-0.9-0.8-0.8
Number of responses in last shaping day0.00.00.10.10.1-0.30.0-0.2-0.0-0.2-0.1-0.3