Hub : Genes

Fzd3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Fzd3 0.06 0.04 1.2e-05 0.06 0.05 0.06 0.05 1.1e-06 3.1e-05 6.9e-06 9.8e-06
2 pVTA gene expression Fzd3 0.05 0.03 2.4e-05 0.06 0.06 0.07 0.06 8.4e-06 7.6e-06 2.7e-06 2.0e-05
3 NAcc mRNA stability Fzd3 0.05 0.02 4.5e-08 0.05 0.05 0.07 0.05 1.1e-08 3.4e-08 3.3e-10 9.5e-08
4 IL mRNA stability Fzd3 0.45 0.14 2.1e-08 0.14 0.19 0.17 0.2 3.5e-04 2.4e-05 6.9e-05 1.4e-05
5 Adipose gene expression Fzd3 0.03 0.02 3.6e-03 0.02 0.01 0.01 0.01 2.0e-03 7.5e-03 8.6e-03 8.4e-03
6 RMTg gene expression Fzd3 0.17 0.09 4.3e-03 0.06 0.06 0.09 0.1 9.3e-03 1.3e-02 2.4e-03 1.5e-03
7 LHb mRNA stability Fzd3 0.18 0.11 5.9e-03 0.05 0.1 0.08 0.08 2.6e-02 2.5e-03 5.8e-03 5.6e-03
8 OFC mRNA stability Fzd3 0.25 0.12 1.1e-04 0.14 0.09 0.13 0.11 4.2e-04 4.1e-03 6.1e-04 1.3e-03
9 Brain mRNA stability Fzd3 0.31 0.12 0.0e+00 0.28 0.28 0.26 0.27 6.0e-26 6.9e-26 9.8e-25 1.3e-25
10 PL mRNA stability Fzd3 0.06 0.03 6.8e-06 0.05 0.05 0.06 0.05 1.9e-06 1.3e-06 8.7e-07 1.6e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.61.01.8-1.2-1.1-0.9-0.91.2-1.3-0.1-1.3-0.2-0.0
Area under the delay curve2.83.28.82.81.41.91.6-2.63.0-0.0-0.30.7-0.5
BMI with tail0.20.72.31.50.60.60.9-1.21.3-0.2-0.10.80.2
BMI without tail0.10.30.7-0.1-0.6-0.8-0.20.2-0.2-0.9-0.80.0-0.2
Body weight0.83.65.82.41.92.02.2-2.01.71.50.92.41.5
Weight adjusted by age2.94.49.71.32.51.92.1-1.30.72.63.12.12.3
Bone surface0.30.51.2-1.0-0.6-0.5-0.81.0-1.10.3-0.8-0.10.1
Bone volume0.30.51.7-0.7-0.7-0.5-0.80.7-0.6-0.0-1.3-0.4-0.4
Breakpoint value in progressive ratio session0.50.61.81.10.30.70.6-1.01.3-0.3-0.40.1-0.4
Number of licking bursts0.20.30.90.7-0.1-0.00.1-0.70.8-0.8-0.9-0.2-0.3
Context. condit. distance diff. score4.04.910.2-1.3-2.5-2.7-2.31.2-0.6-3.2-2.3-2.4-2.3
Locomotion velocity, session 10.10.10.70.40.00.40.0-0.40.40.2-0.90.1-0.2
Locomotion distance, session 10.10.10.70.10.30.6-0.0-0.1-0.10.9-0.3-0.00.0
Locomotion velocity, session 20.10.20.40.50.30.60.0-0.40.50.4-0.5-0.2-0.4
Locomotion distance, session 20.20.31.4-0.20.10.8-0.00.3-0.51.2-0.50.10.2
Locomotion velocity, session 30.70.81.80.90.80.51.2-1.00.80.50.61.30.9
Locomotion distance, session 30.20.30.80.80.20.10.5-0.80.9-0.3-0.30.40.0
Stereotopy head waving bouts, day 30.91.03.5-0.30.80.60.70.4-0.81.21.90.91.4
Stereotopy head waving duration, day 31.31.63.30.71.41.21.5-0.60.31.41.81.31.3
Locomotion velocity, session 74.14.510.3-1.2-2.6-2.3-2.11.2-0.7-3.2-2.5-2.1-2.0
Locomotion distance, session 75.16.411.2-1.8-3.2-2.7-2.61.8-1.3-3.1-3.3-2.3-2.2
Stereotopy head waving bouts, day 72.02.23.21.21.71.71.8-1.21.01.61.51.61.4
Stereotopy head waving duration, day 73.64.36.41.72.42.12.5-1.71.32.02.52.22.0
Locomotion velocity, session 80.40.40.90.2-0.5-0.6-0.4-0.20.5-0.9-1.0-0.7-0.9
Locomotion distance, session 81.21.84.2-0.8-1.5-1.2-1.40.8-0.4-1.5-2.1-1.4-1.5
Degree of sensitization distance8.08.211.4-2.6-3.4-3.0-3.32.6-2.2-2.9-2.9-3.1-2.5
Degree of sensitization stereotypy1.21.31.81.31.41.31.4-1.31.30.80.80.90.6
Conditioned locomotion0.91.11.6-0.9-1.1-1.3-1.10.9-0.7-1.2-0.8-1.2-1.0
Cocaine response after cond. corrected1.31.53.9-0.2-1.3-1.2-1.00.20.2-2.0-1.7-1.2-1.6
Cocaine response after cond. not corrected1.21.44.40.1-1.2-1.0-0.8-0.00.4-1.7-2.1-1.0-1.4
Cocaine response before conditioning0.50.61.40.50.61.00.7-0.50.21.2-0.00.91.0
Saline control response0.50.61.70.20.90.90.6-0.2-0.11.31.10.80.9
Bone: connectivity density1.21.95.5-2.0-1.3-1.2-1.11.9-2.40.1-0.70.20.9
Bone: cortical apparent density0.20.20.60.7-0.0-0.20.3-0.70.8-0.7-0.40.2-0.2
Bone: cortical area0.50.82.31.30.70.70.3-1.31.50.0-0.7-0.3-0.8
Bone: cortical porosity1.41.52.31.51.51.41.2-1.51.41.00.90.80.5
Bone: cortical porosity1.71.82.91.41.71.61.4-1.41.31.41.31.00.8
Bone: cortical thickness0.91.54.71.90.90.80.7-1.92.2-0.3-0.5-0.1-0.7
Bone: cortical thickness2.32.76.01.4-0.5-0.4-0.7-1.42.1-2.1-2.1-1.7-2.5
Bone: cortical tissue density0.20.20.60.6-0.1-0.30.2-0.60.7-0.8-0.50.2-0.2
Condit. Reinf. active minus inactive responses0.60.61.20.51.01.10.8-0.60.41.01.00.60.7
Condit. Reinf. active-inactive response ratio0.10.10.5-0.10.30.20.30.1-0.30.30.70.20.4
Condit. Reinf. active responses0.60.71.90.71.01.40.8-0.80.61.10.60.60.7
Condit. Reinf. inactive responses0.40.41.30.50.71.10.4-0.60.41.00.10.50.6
Incentive salience index mean1.82.23.71.51.81.91.4-1.51.31.51.31.11.1
Condit. Reinf. lever presses1.82.54.11.91.92.01.4-1.91.81.50.81.20.9
Condit. Reinf. active minus inactive responses0.20.30.7-0.4-0.4-0.2-0.70.5-0.4-0.3-0.3-0.9-0.7
Condit. Reinf. active-inactive response ratio0.10.10.3-0.3-0.3-0.2-0.30.3-0.2-0.40.0-0.5-0.4
Condit. Reinf. active responses0.30.40.8-0.6-0.6-0.3-0.80.7-0.6-0.4-0.7-0.9-0.8
Condit. Reinf. inactive responses0.81.01.5-1.0-1.1-0.7-1.21.1-1.0-0.5-1.2-1.0-0.8
Condit. Reinf. lever presses0.40.51.7-0.10.60.70.50.2-0.51.30.80.80.9
Condit. Reinf. lever reinforcers received0.10.20.4-0.3-0.3-0.0-0.50.4-0.3-0.2-0.4-0.6-0.5
Conditioned reinforcement - actives2.74.66.7-2.6-2.4-2.3-2.52.5-2.4-1.4-1.8-1.7-1.3
Conditioned reinforcement - inactives0.81.22.8-1.6-1.1-1.0-1.21.4-1.7-0.2-0.9-0.20.4
Conditioned locomotion1.82.33.6-0.8-1.7-1.6-1.80.9-0.5-1.9-1.6-1.7-1.9
Patch foraging indifference point 0 sec0.71.24.10.21.01.80.7-0.0-0.22.00.71.11.2
Patch foraging indifference point AUC1.01.53.2-0.4-1.1-1.7-1.00.20.4-1.7-1.2-1.4-1.8
Delay disc. indifference point, 0s delay0.10.10.80.30.20.90.00.20.10.60.20.10.1
Delay disc. indifference point, 16s delay1.61.75.31.80.60.60.7-1.92.3-0.7-1.5-0.2-1.0
Delay disc. indifference point, 2s delay0.70.72.41.10.91.60.6-0.80.90.80.50.50.1
Delay disc. indifference point, 24s delay1.82.05.61.90.30.60.4-1.82.4-1.1-1.8-0.5-1.5
Delay disc. indifference point, 4s delay2.72.96.02.31.71.91.8-2.22.50.61.01.10.3
Delay disc. indifference point, 8s delay2.73.27.82.81.52.01.9-2.52.8-0.0-0.10.9-0.2
Indifference point function ln k0.91.53.30.81.21.81.2-0.60.21.61.21.31.4
Indifference point function log k0.91.53.30.81.21.81.2-0.60.21.61.21.31.4
Patch foraging total patch changes 0 sec0.91.74.70.61.32.11.0-0.40.22.21.01.31.3
Patch foraging total patch changes 12 sec0.10.10.30.50.30.40.1-0.50.50.4-0.40.1-0.1
Patch foraging total patch changes 18 sec0.30.40.8-0.4-0.5-0.7-0.90.3-0.1-0.4-0.8-0.7-0.8
Patch foraging total patch changes 24 sec0.20.31.00.20.70.80.4-0.30.41.00.20.40.2
Patch foraging total patch changes 6 sec0.00.00.10.10.20.30.2-0.00.20.2-0.30.20.1
Patch foraging time to switch 0 sec0.10.20.3-0.2-0.6-0.1-0.60.3-0.5-0.4-0.5-0.3-0.1
Patch foraging water rate 0 sec0.51.11.61.11.31.11.2-1.21.21.00.71.00.7
Patch foraging water rate 12 sec0.51.03.30.41.31.00.9-0.80.51.21.80.60.8
Patch foraging water rate 18 sec2.43.76.12.22.11.92.5-2.12.11.21.61.91.0
Patch foraging water rate 24 sec0.10.10.40.10.2-0.2-0.0-0.30.2-0.30.6-0.4-0.3
Patch foraging water rate 6 sec1.31.92.91.01.71.41.5-1.11.01.71.71.30.9
Seeking ratio, delayed vs. immediate footshock0.10.20.6-0.10.20.5-0.10.1-0.40.60.10.40.8
Distance traveled before self-admin0.30.41.2-0.40.60.60.50.3-0.31.11.00.40.4
Distance traveled after self-admin0.30.40.80.60.90.80.7-0.70.60.80.50.3-0.0
Extensor digitorum longus weight4.919.131.45.65.04.15.1-5.65.42.53.03.61.7
Bone: elastic displacement0.20.20.7-0.50.30.3-0.20.5-0.60.80.6-0.10.2
Bone: elastic work0.81.02.70.71.31.40.9-0.70.51.70.70.80.8
Bone: endosteal estimation0.10.10.3-0.5-0.2-0.1-0.30.5-0.60.4-0.5-0.0-0.0
Bone: endosteal perimeter0.30.61.7-1.2-0.3-0.1-0.51.2-1.30.8-0.1-0.20.1
Epididymis fat weight0.10.20.40.40.10.3-0.0-0.20.6-0.4-0.3-0.5-0.7
Delta time in closed arm before/after self-admin0.60.51.2-0.9-0.7-0.7-1.10.7-0.9-0.4-0.7-0.5-0.1
Delta time in open arm before/after self-admin0.30.30.60.80.60.30.6-0.40.50.10.30.70.4
Diff in mean of infusions in LGA sessions5.16.29.02.82.63.02.8-2.52.11.92.22.62.2
Delay discount exponential model param3.53.910.0-3.1-1.7-2.1-1.82.8-3.2-0.10.1-0.90.4
Extinction: sum of active levers before priming0.10.20.40.50.10.50.2-0.60.50.1-0.50.40.2
Active lever presses in extinction session 61.01.01.8-0.6-1.2-1.1-1.00.5-0.3-1.3-0.8-1.3-1.2
Bone: final force0.50.82.41.40.80.70.6-1.41.50.2-0.30.2-0.3
Bone: final moment0.50.81.81.31.01.00.8-1.31.30.70.10.50.1
Food consumed during 24 hour testing period0.30.41.10.00.70.50.60.0-0.21.00.80.60.6
Glucose0.30.51.30.6-0.2-0.4-0.1-0.60.9-1.1-0.5-0.8-1.1
Heart weight0.10.10.3-0.4-0.10.20.00.5-0.5-0.00.4-0.10.2
Delay discount hyperbolic model param3.13.48.6-2.8-1.6-2.1-1.72.6-2.9-0.2-0.1-0.80.3
Intermittent access intake day 1-15 change0.61.32.1-1.4-1.3-1.2-1.41.2-1.4-0.5-0.5-1.1-0.7
Intermittent access intake escalation0.30.61.2-1.0-0.8-0.8-1.00.8-1.1-0.2-0.2-0.7-0.4
Intermittent access intake escalation 20.20.20.6-0.6-0.3-0.4-0.40.4-0.8-0.10.5-0.3-0.1
Intermitt. access day 1 inactive lever presses0.20.71.6-1.2-0.9-0.9-0.91.0-1.3-0.5-0.1-0.40.5
Intermitt. access day 15 inactive lever presses0.30.62.3-0.50.4-0.20.60.0-0.40.61.40.91.5
Intermitt. access escalation Index0.10.20.6-0.2-0.40.0-0.50.4-0.4-0.3-0.7-0.3-0.4
Intermittent access day 1 total infusions0.60.91.9-0.6-1.0-0.9-1.20.8-0.5-0.9-1.4-0.9-1.2
Intermittent access day 15 total infusions1.52.23.5-1.6-1.7-1.6-1.91.6-1.5-1.2-1.1-1.4-1.2
Intermittent access terminal intake (last 3 days)1.82.43.7-1.6-1.7-1.9-1.81.6-1.5-1.4-0.8-1.5-1.4
Intermittent access total infusions3.23.85.6-1.9-2.2-2.3-2.41.8-1.5-1.9-1.7-2.0-1.8
Intermittent access day 1 locomotion0.20.20.80.60.10.60.1-0.40.5-0.2-0.90.4-0.1
Intermittent access day 15 total locomotion0.20.40.7-0.5-0.7-0.9-0.80.6-0.7-0.60.1-0.5-0.5
Intermittent access total locomotion0.10.10.2-0.1-0.3-0.2-0.50.3-0.4-0.5-0.1-0.1-0.3
Intermittent access standard deviation0.40.91.6-1.1-0.4-1.1-0.91.0-0.8-0.31.3-1.1-1.0
Left kidney weight0.83.86.41.71.92.22.3-1.50.91.91.92.52.2
Right kidney weight1.67.313.22.12.73.02.9-1.91.13.02.53.63.4
Cocaine induced anxiety1.31.83.61.21.51.91.5-1.21.01.31.31.11.1
Post-drug Anxiety2.02.14.90.81.42.21.8-0.80.41.70.91.61.8
Baseline Anxiety0.10.21.2-0.1-0.40.10.20.2-0.2-0.2-1.10.40.2
Tail length0.20.72.0-0.60.20.30.30.5-1.11.20.61.11.4
Length with tail0.72.95.50.91.62.01.7-0.80.22.41.62.12.2
Length without tail1.96.19.22.72.83.02.7-2.42.12.42.02.41.9
Times rat made contact with spout0.10.20.2-0.3-0.5-0.5-0.30.3-0.2-0.5-0.5-0.4-0.4
Lifetime Intake2.93.55.1-1.9-2.1-2.1-2.31.8-1.5-1.7-1.6-1.9-1.8
Liver weight, left2.44.16.11.42.42.22.1-1.30.82.42.52.32.1
Liver weight, right0.91.53.21.81.21.11.5-1.71.80.30.21.00.1
Locomotor activity4.67.211.22.03.23.32.8-2.01.63.32.92.62.6
Locomotor testing distance1.22.26.9-0.11.41.91.0-0.0-0.42.61.61.21.9
Locomotor testing rearing1.73.511.3-0.71.32.11.00.6-1.43.41.71.92.6
Locomotion in novel chamber0.40.51.50.70.30.40.7-0.90.50.1-1.20.80.5
Locomotion in novel chamber post-restriction0.30.41.00.70.0-0.8-0.6-0.60.8-0.5-0.6-0.5-1.0
Fecal boli incidents, locomotor time 10.10.20.50.60.50.50.3-0.10.10.20.70.2-0.5
Change in fecal boli incidents, locomotor task0.10.10.8-0.30.1-0.20.20.2-0.20.10.20.40.9
Time >=10cm from walls, locomotor time 10.70.82.40.00.70.50.7-0.0-0.31.21.21.11.5
Bouts of movement, locomotor time 10.20.21.10.10.1-0.3-0.40.3-0.1-0.31.0-0.5-0.5
Total resting periods, locomotor time 10.50.61.5-0.1-0.4-0.9-0.90.5-0.1-1.10.4-1.1-1.2
Rest time, locomotor task time 10.91.22.5-0.3-1.2-1.2-1.00.20.1-1.6-1.1-1.3-1.5
Distance moved, locomotor task time 10.10.20.5-0.4-0.00.10.20.2-0.30.60.60.30.7
Vertical activity count, locomotor time 10.61.43.70.51.31.11.1-0.70.41.91.31.41.4
Time >=10cm from walls, locomotor time 20.20.30.9-0.50.20.10.50.3-0.40.90.70.60.9
Bouts of movement, locomotor time 20.61.02.51.60.80.81.0-1.31.6-0.30.50.3-0.4
Total resting periods, locomotor time 20.71.23.41.80.80.71.1-1.51.8-0.50.60.3-0.5
Rest time, locomotor task time 21.01.33.31.3-0.0-0.50.1-1.31.8-1.6-0.2-0.7-1.7
Distance moved, locomotor task time 20.30.40.9-0.9-0.20.1-0.20.8-0.80.9-0.20.10.7
Vertical activity count, locomotor time 20.30.42.0-0.20.40.70.2-0.0-0.11.4-0.50.50.7
Light reinforcement 10.10.10.6-0.3-0.6-0.3-0.30.1-0.1-0.5-0.8-0.3-0.1
Light reinforcement 20.71.12.3-0.8-1.3-1.5-0.90.7-0.4-1.5-1.0-0.9-0.9
Bone: marrow area0.10.20.4-0.6-0.3-0.2-0.40.6-0.60.3-0.6-0.1-0.2
Bone: maximum diameter0.20.41.10.70.20.20.0-0.71.0-0.3-0.7-0.6-1.1
Bone: maximum force0.71.33.71.61.01.00.7-1.71.90.4-0.60.2-0.6
Bone: maximum moment0.81.33.01.61.31.31.0-1.61.70.9-0.20.5-0.1
Mean time between licks in bursts1.02.47.0-2.3-1.6-1.0-1.32.3-2.60.0-0.7-0.30.5
Mean num. licks in bursts0.20.30.8-0.9-0.3-0.4-0.40.9-0.90.30.5-0.2-0.1
Cd content in liver2.22.44.90.51.61.51.6-0.4-0.02.22.11.91.9
Co content in liver0.50.61.61.10.70.30.6-1.11.2-0.20.6-0.0-0.5
Cu content in liver0.30.30.70.80.50.50.8-0.80.70.10.30.60.3
Fe content in liver0.50.61.8-1.2-0.7-0.2-0.51.2-1.40.10.4-0.00.5
K content in liver0.70.61.3-0.6-1.1-1.0-0.80.6-0.6-1.0-1.0-0.5-0.3
Mg content in liver1.61.62.8-1.6-1.6-1.0-1.11.6-1.7-0.7-1.2-0.9-0.5
Mn content in liver1.21.32.2-1.2-1.4-0.9-1.31.2-1.1-0.7-1.5-1.0-0.8
Na content in liver6.36.89.12.73.03.02.9-2.72.32.52.42.42.0
Rb content in liver0.50.61.7-1.1-0.4-0.4-0.11.1-1.30.20.70.30.8
Se content in liver0.50.61.9-0.20.51.10.30.2-0.61.40.80.61.1
Sr content in liver0.60.51.5-0.9-0.2-0.2-0.10.9-1.20.70.70.60.9
Zn content in liver0.40.51.7-1.0-0.4-0.2-0.41.1-1.30.5-0.10.10.4
Bone: minimum diameter0.20.40.80.70.80.80.3-0.70.90.60.1-0.1-0.4
Time in familiar zone, hab. session 10.80.81.5-0.4-0.8-0.8-1.00.4-0.1-1.0-1.0-1.2-1.2
Time in novel zone, hab. session 11.21.22.11.31.11.01.4-1.31.20.40.91.10.7
Total zone transitions, hab. session 10.30.41.10.80.40.60.2-0.81.00.2-0.7-0.2-0.6
Total locomotion distance, hab. session 10.20.31.60.2-0.10.3-0.3-0.20.40.1-1.3-0.5-0.7
Locomotion velocity, hab. session 10.20.21.50.30.10.6-0.1-0.20.30.6-1.2-0.1-0.3
Time in familiar zone, hab. session 20.30.31.0-0.5-0.7-1.0-0.60.4-0.3-0.8-0.3-0.5-0.4
Time in novel zone, hab. session 20.10.10.40.20.20.60.1-0.20.30.3-0.2-0.0-0.1
Total zone transitions, hab. session 20.50.61.20.71.01.10.8-0.70.61.10.40.50.3
Total locomotion distance, hab. session 20.10.10.40.40.20.50.1-0.30.50.3-0.6-0.2-0.3
Locomotion velocity, hab. session 20.20.30.60.70.50.80.3-0.60.70.5-0.50.1-0.2
Novel to familiar place preference ratio0.30.40.9-0.6-0.5-0.4-0.80.6-0.4-0.2-0.6-0.9-0.8
Novelty place preference0.30.30.6-0.6-0.4-0.3-0.70.6-0.4-0.0-0.4-0.8-0.6
Time in novel zone, NPP test0.10.10.3-0.5-0.1-0.1-0.50.5-0.30.2-0.1-0.5-0.4
Total zone transitions, NPP test0.10.10.50.10.00.6-0.1-0.10.00.4-0.7-0.1-0.1
Total locomotion distance, NPP test0.91.33.0-1.3-1.2-0.4-1.31.3-1.4-0.0-1.7-0.8-0.4
Locomotion velocity, NPP test1.11.53.8-1.4-1.4-0.6-1.41.4-1.4-0.2-1.9-0.9-0.6
Intraocular pressure1.11.54.9-1.9-1.0-0.7-1.21.7-2.20.2-0.2-0.60.2
Delta distance traveled before/after self-admin0.50.51.51.20.70.50.5-1.21.00.00.20.3-0.1
Delta ambulatory time before/after self-admin0.30.41.01.00.60.40.2-1.00.90.0-0.1-0.1-0.4
Parametrial fat weight1.53.65.8-1.9-2.2-1.8-2.42.0-1.8-1.3-2.0-1.9-1.4
Pavlov. Cond. lever latency0.80.91.7-1.1-1.2-1.3-0.91.2-1.1-0.8-0.6-0.6-0.4
Pavlov. Cond. magazine entry latency0.50.71.20.71.00.80.8-0.80.60.71.10.80.9
Pavlov. Cond. change in total contacts2.32.54.11.91.91.81.5-2.02.01.30.91.00.4
Pavlov. Cond. index score2.32.94.42.02.01.91.8-2.11.81.31.21.51.2
Pavlov. Cond. latency score1.72.13.21.71.71.71.5-1.81.51.21.11.21.0
Pavlov. Cond. lever contacts1.01.21.81.31.31.31.1-1.41.20.80.80.80.6
Pavlov. Cond. magazine entry number1.92.43.3-1.7-1.8-1.6-1.71.8-1.5-1.2-1.4-1.4-1.1
Pavlov. Cond. intertrial magazine entries0.20.20.80.00.30.80.3-0.0-0.20.90.10.40.5
Pavlov. Cond. lever-magazine prob. diff.2.73.35.12.12.12.01.9-2.32.01.31.21.61.2
Pavlov. Cond. response bias1.62.03.21.71.71.41.5-1.81.60.91.11.20.9
Pavlov. Cond. lever latency1.92.64.7-0.8-1.8-1.6-1.80.9-0.4-2.2-1.9-1.9-1.8
Pavlov. Cond. magazine entry latency1.31.52.51.61.41.41.3-1.61.51.00.51.00.8
Pavlov. Cond. change in total contacts3.15.07.01.92.62.32.6-1.91.52.42.52.42.1
Pavlov. Cond. index score2.53.44.51.62.12.02.1-1.61.22.11.91.91.8
Pavlov. Cond. latency score2.73.64.71.52.22.02.1-1.61.12.22.02.01.9
Pavlov. Cond. lever contacts1.82.44.60.91.71.61.8-0.90.52.11.71.81.7
Pavlov. Cond. magazine entry number0.40.51.0-1.0-0.7-0.9-0.71.0-1.0-0.60.0-0.3-0.2
Pavlov. Cond. intertrial magazine entries4.87.213.3-3.6-3.0-2.2-3.03.6-3.6-1.3-1.9-1.9-1.0
Pavlov. Cond. lever-magazine prob. diff.2.43.24.21.72.11.92.0-1.71.41.91.71.81.6
Pavlov. Cond. response bias1.92.63.81.41.81.91.9-1.41.12.01.51.71.4
Time in closed arm before self-admin1.31.62.61.31.31.51.6-1.31.00.80.91.61.2
Time in closed arm after self-admin0.10.10.30.20.30.4-0.0-0.50.00.20.30.40.5
Time in open arm before self-admin0.60.61.2-1.1-0.7-0.7-1.10.9-0.80.0-0.7-0.9-0.6
Time in open arm after self-admin0.10.10.20.1-0.0-0.10.30.3-0.20.2-0.20.50.5
Bone: periosteal estimation0.10.10.60.30.10.2-0.1-0.30.40.2-0.8-0.3-0.6
Bone: periosteal perimeter0.00.10.2-0.00.10.2-0.20.00.00.4-0.4-0.2-0.3
Bone: post-yield work3.34.912.80.2-1.7-1.7-1.7-0.21.2-2.9-3.1-2.8-3.6
Progressive ratio test 1 active lever presses1.61.93.1-0.9-1.5-1.5-1.40.9-0.4-1.7-1.7-1.5-1.8
Progressive ratio test 1 breakpoint1.41.73.0-0.8-1.3-1.4-1.30.8-0.2-1.6-1.6-1.5-1.7
Progressive ratio test 1 inactive lever presses0.60.82.0-1.1-1.0-0.7-0.91.1-1.2-0.5-1.4-0.10.0
Progressive ratio test 2 active lever presses0.60.71.4-1.1-0.8-0.8-0.91.2-1.2-0.40.1-0.5-0.5
Progressive ratio test 2 breakpoint0.40.51.1-1.0-0.6-0.6-0.71.0-1.1-0.20.2-0.3-0.4
Progressive ratio test 2 inactive lever presses1.01.73.6-1.9-1.3-1.5-1.41.7-1.9-0.7-0.4-0.6-0.2
Incentive Sensitization - Responses0.71.02.8-0.50.50.50.20.7-1.21.41.71.01.0
Incentive Sensitization - Breakpoint0.81.02.7-0.60.50.50.20.7-1.31.41.61.01.1
Sum of active levers in priming session hrs 5-60.30.30.9-0.2-1.0-0.5-0.30.10.1-0.9-0.6-0.4-0.4
Progressive ratio1.11.73.41.41.31.11.5-1.00.91.21.31.81.2
Food seeking constrained by brief footshock0.81.02.7-0.5-1.2-1.5-0.90.4-0.1-1.7-0.5-1.0-0.9
Seeking ratio, punishment vs. effort1.01.43.0-0.9-1.2-1.3-1.20.5-0.3-1.6-0.8-1.7-1.4
Retroperitoneal fat weight0.31.22.0-0.8-1.3-0.9-1.31.0-0.9-0.9-1.4-1.1-0.9
Reaction time number correct0.20.41.3-0.9-0.5-0.5-0.50.9-1.1-0.1-0.0-0.10.0
Reaction time mean minus median0.51.41.91.01.31.31.2-0.80.61.31.41.31.3
Reaction time mean minus median AUC0.30.81.90.60.90.90.8-0.30.11.10.91.41.3
Reaction time num false alarms0.91.32.60.90.81.41.4-0.90.61.30.11.61.3
Reaction time num false alarms AUC0.81.22.21.00.91.41.4-0.90.71.20.31.51.1
Reaction time trials correct on left0.20.41.3-0.9-0.5-0.5-0.50.9-1.1-0.1-0.0-0.10.0
Reaction time trials on left0.30.51.6-1.0-0.6-0.6-0.61.0-1.3-0.2-0.0-0.20.0
Reaction time mean0.30.51.5-0.30.60.30.60.2-0.40.81.20.91.1
Reaction time mean AUC0.60.92.0-0.00.90.60.90.0-0.31.11.41.31.4
Median of all reaction times0.30.41.2-0.60.3-0.10.30.4-0.60.51.10.60.9
Reaction time omissions1.11.65.2-1.8-1.2-1.0-1.21.9-2.3-0.1-0.4-0.20.4
Reaction time false alarm rate0.91.21.81.30.91.31.3-1.31.20.80.11.20.8
Reaction time premature initiation rate0.30.51.30.90.80.40.5-0.81.2-0.01.0-0.2-0.2
Reaction time premature initiations0.10.10.60.20.3-0.10.0-0.10.4-0.20.8-0.4-0.3
Std. dev. reaction times0.20.31.00.10.60.30.4-0.0-0.10.61.00.60.7
Reaction time trials completed0.30.51.6-1.0-0.6-0.6-0.61.0-1.3-0.2-0.0-0.20.0
Reaction time trials AUC0.30.61.9-1.1-0.7-0.7-0.61.1-1.4-0.10.0-0.20.0
Run reversals in cocaine runway, females0.80.81.4-0.9-1.1-1.2-0.70.1-0.0-1.0-1.0-1.1-0.8
Run reversals in cocaine runway, males2.22.24.52.01.81.21.7-1.92.10.71.01.00.2
Latency to leave start box in cocaine runway1.11.23.1-1.4-0.6-1.2-1.31.8-1.7-0.20.2-0.9-0.4
Latency to leave start box in cocaine runway, F0.30.30.8-0.20.4-0.2-0.30.9-0.90.40.90.00.2
Latency to leave start box in cocaine runway, M1.11.02.6-1.6-0.9-1.0-0.91.4-1.6-0.1-0.2-0.6-0.1
Std. dev. time between licks in bursts0.71.03.1-1.5-0.60.1-0.81.5-1.81.0-0.1-0.10.7
Total sessions with >9 infusions0.60.81.1-0.9-1.0-1.0-1.01.0-1.0-0.6-1.0-0.3-0.3
Short access day 1 total inactive lever presses0.30.31.0-0.2-0.1-0.9-0.70.5-0.3-0.8-0.3-0.4-1.0
Short access day 10 total inactive lever presses0.10.30.7-0.6-0.5-0.6-0.80.7-0.7-0.4-0.4-0.4-0.4
Short access day 1 total infusions2.43.25.1-1.8-1.7-2.2-2.32.0-1.8-1.5-1.4-1.6-1.5
Short access day 10 total infusions0.20.30.8-0.2-0.3-0.6-0.70.20.1-0.3-0.7-0.6-0.9
Short access total infusions0.71.01.7-1.0-0.9-1.1-1.31.1-0.8-0.7-0.7-1.0-1.1
Short access day 1 locomotion0.10.20.60.10.30.40.20.1-0.30.6-0.00.80.4
Short access day 10 total locomotion0.20.41.10.50.60.90.7-0.1-0.10.50.51.10.9
Short access total locomotion0.40.41.10.50.70.90.6-0.30.00.70.31.10.8
One hour access (0.3 mA shock)1.71.94.3-0.8-1.5-1.0-1.50.8-0.5-1.4-2.1-1.6-1.8
Compulsive drug intake0.50.64.70.0-0.70.1-0.3-0.0-0.0-0.4-2.2-0.2-0.1
One hour access (shock baseline)1.01.52.3-1.3-1.2-1.3-1.51.3-1.0-1.1-0.5-1.4-1.4
Social response proportion1.82.03.9-1.7-1.4-1.6-1.61.9-2.0-1.20.0-1.2-0.6
Social responses2.33.05.9-2.3-1.7-1.3-2.12.4-2.4-0.8-0.3-1.7-0.8
Social time0.91.23.0-0.50.40.90.70.6-1.01.61.01.51.7
Soleus weight0.20.51.51.20.40.50.6-1.11.2-0.5-0.4-0.0-0.6
Bone: stiffness0.61.02.41.51.00.91.0-1.51.60.40.20.70.1
Tibialis anterior weight5.117.528.75.44.74.14.9-5.25.02.72.33.82.1
Time to tail flick, vehicle, before self-admin0.60.72.11.00.60.50.8-1.41.4-0.1-0.40.40.2
Time to tail flick, vehicle, after self-admin0.50.72.10.80.70.10.8-1.51.3-0.21.10.30.2
Time to tail flick, test, before self-admin0.30.32.5-0.1-0.30.20.0-0.2-0.10.1-1.60.40.3
Time to tail flick, test, after self-admin3.94.06.4-2.4-2.3-2.4-2.32.3-2.5-1.4-1.3-1.5-0.7
Delta time to tail flick, vehicle, before/after SA0.60.51.5-1.0-0.6-1.2-0.50.6-0.7-0.60.8-0.6-0.3
Delta time to tail flick, test, before/after SA3.13.25.3-2.2-1.9-2.3-1.92.2-2.0-1.5-0.1-1.6-0.8
Tibia length2.05.611.51.22.32.42.2-1.20.43.41.93.33.4
Ambulatory time before self-admin0.10.10.5-0.30.40.30.20.2-0.10.60.70.10.0
Ambulatory time after self-admin1.11.32.51.21.61.31.2-1.31.21.10.90.70.2
Bone: tissue strength0.20.20.4-0.6-0.20.10.00.6-0.60.5-0.30.30.2
Total heroin consumption0.70.81.61.30.91.00.9-1.11.10.41.10.70.1
Bone: trabecular number0.71.12.8-1.5-1.1-0.9-1.01.5-1.7-0.0-0.8-0.20.3
Bone: trabecular spacing1.41.85.32.11.31.11.2-2.12.3-0.00.30.3-0.4
Bone: trabecular thickness0.20.20.50.60.30.50.3-0.60.60.3-0.70.40.1
Bone: trabecular tissue density2.43.65.82.42.11.82.0-2.42.30.91.61.61.0
Water consumed over 24 hours0.60.81.31.01.10.91.1-1.00.90.90.70.90.6
Number of responses in last shaping day0.60.72.11.41.00.70.5-1.01.10.30.60.6-0.1