Hub : Genes

Fzd3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Fzd3 0.45 0.14 3.6e-09 0.17 0.22 0.24 0.25 8.2e-05 6.7e-06 2.1e-06 1.1e-06
2 Brain gene expression Fzd3 0.05 0.03 9.8e-05 0.06 0.05 0.06 0.06 1.1e-06 2.3e-05 1.6e-06 1.6e-06
3 Adipose gene expression Fzd3 0.03 0.02 8.7e-04 0.03 0.02 0.02 0.02 5.3e-04 1.5e-03 4.3e-03 1.5e-03
4 LHb mRNA stability Fzd3 0.17 0.1 4.5e-03 0.09 0.11 0.1 0.1 3.3e-03 1.8e-03 2.6e-03 2.1e-03
5 Brain mRNA stability Fzd3 0.29 0.1 0.0e+00 0.25 0.26 0.25 0.25 3.4e-23 1.8e-24 3.2e-23 1.5e-23
6 OFC mRNA stability Fzd3 0.21 0.12 1.4e-03 0.13 0.03 0.06 0.06 6.2e-04 5.7e-02 1.9e-02 1.7e-02
7 RMTg gene expression Fzd3 0.17 0.1 4.6e-03 0.05 0.09 0.12 0.1 1.9e-02 1.7e-03 4.2e-04 1.2e-03
8 PL mRNA stability Fzd3 0.07 0.04 2.3e-04 0.03 0.03 0.03 0.03 2.5e-04 1.8e-04 4.2e-04 2.3e-04
9 NAcc mRNA stability Fzd3 0.05 0.03 4.2e-05 0.03 0.04 0.04 0.03 4.7e-04 3.4e-05 1.1e-05 7.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.40.72.3-1.01.5-1.00.1-0.01.00.9-0.00.4
Area under the delay curve2.42.57.60.8-2.82.4-0.30.60.3-2.5-0.7-1.1
BMI with tail0.51.65.10.9-1.42.2-0.31.10.0-2.30.3-0.7
BMI without tail0.61.24.2-1.70.5-0.4-1.3-0.52.1-0.3-0.80.1
Body weight1.04.37.22.4-2.12.61.62.7-1.6-1.91.9-1.5
Weight adjusted by age3.54.08.22.7-1.11.12.61.9-2.90.22.3-1.5
Bone surface0.20.31.4-0.51.2-0.70.4-0.10.30.6-0.10.0
Bone volume0.20.41.2-0.80.9-0.4-0.1-0.31.10.0-0.60.1
Breakpoint value in progressive ratio session0.40.51.1-0.4-0.60.7-0.7-0.11.0-0.9-0.9-0.2
Number of licking bursts0.30.41.2-0.4-0.60.7-0.70.31.1-0.8-0.2-0.1
Context. condit. distance diff. score3.34.09.0-2.41.4-1.2-3.0-2.02.30.2-1.92.2
Locomotion velocity, session 10.10.10.3-0.3-0.30.40.10.00.5-0.5-0.3-0.3
Locomotion distance, session 10.20.20.6-0.5-0.1-0.00.5-0.30.8-0.2-0.6-0.8
Locomotion velocity, session 20.20.20.7-0.1-0.50.50.1-0.30.3-0.5-0.8-0.5
Locomotion distance, session 20.20.30.7-0.60.3-0.30.8-0.30.80.3-0.6-0.8
Locomotion velocity, session 30.91.01.91.1-1.21.10.71.3-0.9-0.71.4-0.2
Locomotion distance, session 30.40.41.20.2-1.10.9-0.10.70.4-0.80.4-0.2
Stereotopy head waving bouts, day 30.80.92.51.0-0.2-0.41.20.7-1.61.01.2-0.5
Stereotopy head waving duration, day 31.82.24.21.9-1.30.81.71.4-2.1-0.21.6-1.4
Locomotion velocity, session 73.53.88.1-2.41.2-1.2-2.8-1.62.50.6-1.62.4
Locomotion distance, session 74.55.711.3-3.22.2-1.8-2.8-1.83.41.0-2.02.5
Stereotopy head waving bouts, day 71.71.93.81.5-2.01.41.31.4-1.3-1.01.2-1.2
Stereotopy head waving duration, day 73.54.36.42.5-2.41.81.92.2-2.5-1.12.2-1.7
Locomotion velocity, session 80.40.41.1-0.7-0.10.2-1.0-0.61.1-0.6-0.80.1
Locomotion distance, session 81.42.04.6-2.01.0-0.7-1.6-1.42.10.0-1.61.0
Degree of sensitization distance7.67.611.7-3.43.0-2.7-2.8-2.82.91.7-2.62.6
Degree of sensitization stereotypy1.31.43.71.3-1.91.40.70.9-0.9-1.20.7-1.0
Conditioned locomotion0.40.40.8-0.70.3-0.8-0.9-0.80.70.5-0.60.3
Cocaine response after cond. corrected0.80.93.1-0.9-0.1-0.1-1.8-1.11.0-0.8-1.10.5
Cocaine response after cond. not corrected0.70.82.2-0.90.00.1-1.5-0.81.1-0.8-1.00.5
Cocaine response before conditioning0.30.41.40.40.30.51.21.0-0.40.20.7-0.3
Saline control response0.10.10.40.20.00.10.60.2-0.20.20.1-0.4
Bone: connectivity density1.21.95.8-0.92.2-1.90.50.50.32.40.90.8
Bone: cortical apparent density0.20.20.7-0.2-0.60.4-0.80.10.6-0.60.00.3
Bone: cortical area0.81.23.2-0.1-1.31.3-0.7-0.40.9-1.8-1.2-1.1
Bone: cortical porosity2.02.23.41.9-1.71.71.41.4-1.5-0.91.0-1.7
Bone: cortical porosity1.61.83.31.7-1.61.41.31.0-1.4-0.80.7-1.8
Bone: cortical thickness1.11.85.30.3-2.02.0-0.70.00.8-2.3-0.9-1.1
Bone: cortical thickness2.83.26.4-1.1-1.01.2-2.4-1.62.1-2.5-2.5-0.1
Bone: cortical tissue density0.20.20.7-0.2-0.50.4-0.80.10.6-0.60.00.3
Condit. Reinf. active minus inactive responses0.40.51.00.9-0.40.51.00.7-0.8-0.00.6-0.6
Condit. Reinf. active-inactive response ratio0.20.20.40.50.1-0.20.40.2-0.60.30.6-0.2
Condit. Reinf. active responses0.30.31.00.7-0.40.71.00.7-0.4-0.10.3-0.5
Condit. Reinf. inactive responses0.10.10.70.00.00.40.80.60.00.2-0.1-0.1
Incentive salience index mean1.31.52.51.6-1.21.51.51.2-1.2-0.70.8-1.2
Condit. Reinf. lever presses1.21.63.41.4-1.51.81.41.3-0.8-1.00.4-1.2
Condit. Reinf. active minus inactive responses0.20.30.8-0.30.0-0.4-0.5-0.80.50.2-0.9-0.5
Condit. Reinf. active-inactive response ratio0.10.10.30.0-0.5-0.2-0.5-0.50.1-0.1-0.4-0.4
Condit. Reinf. active responses0.30.40.9-0.70.6-0.6-0.5-0.80.70.3-0.9-0.2
Condit. Reinf. inactive responses1.01.22.8-1.31.7-1.1-0.5-1.01.01.0-1.00.8
Condit. Reinf. lever presses0.40.61.80.70.20.01.30.7-0.80.40.8-1.0
Condit. Reinf. lever reinforcers received0.10.10.4-0.30.3-0.2-0.2-0.50.40.1-0.6-0.5
Conditioned reinforcement - actives5.35.38.9-3.02.8-2.9-1.9-2.62.01.7-1.91.2
Conditioned reinforcement - inactives1.31.53.1-1.51.8-1.4-0.2-0.41.01.6-0.41.2
Conditioned locomotion2.42.84.7-2.21.4-1.3-2.0-2.01.60.4-2.11.2
Patch foraging indifference point 0 sec0.50.83.10.70.00.11.80.8-1.00.60.5-1.1
Patch foraging indifference point AUC1.21.33.3-1.10.10.1-1.8-1.51.1-1.4-1.40.2
Delay disc. indifference point, 0s delay0.10.10.6-0.4-0.2-0.30.2-0.20.30.2-0.80.2
Delay disc. indifference point, 16s delay1.61.64.70.2-1.92.1-0.70.20.7-2.2-0.8-0.4
Delay disc. indifference point, 2s delay0.50.62.10.3-1.10.70.50.0-0.0-0.8-0.6-1.4
Delay disc. indifference point, 24s delay2.12.05.60.1-2.11.9-1.1-0.21.2-2.4-1.4-0.0
Delay disc. indifference point, 4s delay1.81.95.21.3-2.32.10.30.9-0.6-2.00.1-0.7
Delay disc. indifference point, 8s delay3.33.410.51.6-3.22.60.01.1-0.3-2.60.1-1.8
Indifference point function ln k1.01.43.11.4-0.80.61.81.4-1.30.41.2-1.0
Indifference point function log k1.01.43.11.4-0.80.61.81.4-1.30.41.2-1.0
Patch foraging total patch changes 0 sec0.60.93.40.9-0.30.51.81.0-1.10.30.5-1.3
Patch foraging total patch changes 12 sec0.10.20.4-0.50.10.60.0-0.10.5-0.5-0.6-0.5
Patch foraging total patch changes 18 sec0.50.61.4-1.10.7-0.4-0.8-1.10.8-0.4-1.2-0.3
Patch foraging total patch changes 24 sec0.30.42.70.3-0.40.30.70.1-0.1-0.4-0.1-1.7
Patch foraging total patch changes 6 sec0.00.10.2-0.40.10.1-0.00.10.4-0.2-0.2-0.4
Patch foraging time to switch 0 sec0.20.30.6-0.60.5-0.3-0.2-0.10.70.8-0.30.7
Patch foraging water rate 0 sec0.50.91.60.9-0.91.20.80.9-0.6-1.30.6-1.1
Patch foraging water rate 12 sec0.30.51.31.0-0.50.71.00.4-1.1-0.20.4-0.3
Patch foraging water rate 18 sec2.43.36.32.3-2.52.21.21.7-1.3-2.01.5-1.0
Patch foraging water rate 24 sec0.10.10.20.3-0.10.1-0.5-0.5-0.1-0.3-0.30.2
Patch foraging water rate 6 sec1.01.42.71.6-1.11.11.40.8-1.6-0.80.8-1.0
Seeking ratio, delayed vs. immediate footshock0.20.20.90.10.4-0.10.70.4-0.60.90.30.3
Distance traveled before self-admin0.10.10.6-0.2-0.0-0.40.3-0.30.1-0.1-0.1-0.8
Distance traveled after self-admin0.10.10.3-0.30.1-0.1-0.1-0.50.2-0.4-0.40.2
Extensor digitorum longus weight4.517.731.04.8-5.45.62.13.2-3.1-5.42.5-4.0
Bone: elastic displacement0.20.20.70.4-0.0-0.30.8-0.2-0.70.6-0.1-0.4
Bone: elastic work0.81.02.61.2-0.90.81.50.5-0.9-0.50.3-1.6
Bone: endosteal estimation0.00.10.2-0.10.5-0.50.2-0.40.10.2-0.3-0.2
Bone: endosteal perimeter0.20.51.2-0.61.0-1.10.4-0.70.21.0-0.5-0.2
Epididymis fat weight0.10.21.1-0.20.1-0.1-0.6-0.30.00.1-0.61.0
Delta time in closed arm before/after self-admin0.70.61.9-0.21.4-0.70.1-0.3-0.11.30.01.2
Delta time in open arm before/after self-admin0.00.00.2-0.2-0.1-0.2-0.40.10.10.00.1-0.3
Diff in mean of infusions in LGA sessions4.44.98.93.0-2.72.32.02.5-2.3-1.22.1-1.0
Delay discount exponential model param2.72.98.7-1.02.9-2.50.2-0.6-0.12.70.51.3
Extinction: sum of active levers before priming0.70.72.1-1.30.8-0.1-0.8-0.41.50.2-0.80.8
Active lever presses in extinction session 61.00.92.3-1.21.1-0.6-0.9-0.80.90.2-0.91.5
Bone: final force0.60.92.50.5-1.61.4-0.20.20.1-1.5-0.5-0.8
Bone: final moment0.60.92.50.7-1.61.30.30.4-0.2-1.4-0.2-1.1
Food consumed during 24 hour testing period0.20.20.70.5-0.10.00.80.2-0.7-0.00.4-0.6
Glucose0.40.61.8-0.4-0.20.3-1.4-0.70.7-1.1-0.70.6
Heart weight0.20.41.10.9-0.50.00.60.5-1.00.30.70.0
Delay discount hyperbolic model param2.83.08.9-1.33.0-2.6-0.0-0.70.12.70.41.4
Intermittent access intake day 1-15 change0.30.31.1-0.10.6-0.90.0-0.7-0.41.0-0.30.2
Intermittent access intake escalation0.40.30.9-0.20.6-0.9-0.2-1.0-0.20.8-0.5-0.1
Intermittent access intake escalation 20.30.30.90.30.3-0.60.3-0.4-0.90.9-0.00.2
Intermitt. access day 1 inactive lever presses0.80.93.1-0.61.1-1.0-0.10.2-0.31.80.31.4
Intermitt. access day 15 inactive lever presses1.01.13.40.90.0-0.11.41.5-1.00.71.8-0.5
Intermitt. access escalation Index1.41.23.4-1.20.5-0.7-1.2-1.31.9-0.0-1.40.1
Intermittent access day 1 total infusions1.01.22.3-1.30.6-0.6-1.5-1.41.2-0.5-1.30.8
Intermittent access day 15 total infusions1.51.73.8-1.31.1-1.4-1.5-1.90.80.6-1.50.9
Intermittent access terminal intake (last 3 days)1.21.33.8-1.00.8-1.2-1.5-1.90.50.2-1.30.5
Intermittent access total infusions2.42.75.0-1.81.2-1.3-2.2-2.21.30.1-1.91.5
Intermittent access day 1 locomotion0.40.41.4-0.8-0.30.3-0.9-0.21.2-0.8-0.70.1
Intermittent access day 15 total locomotion0.40.51.7-0.50.3-0.5-0.8-0.80.30.3-0.61.3
Intermittent access total locomotion0.20.20.5-0.5-0.2-0.0-0.7-0.40.4-0.1-0.60.6
Intermittent access standard deviation0.70.72.60.30.8-1.10.1-1.3-1.60.5-0.4-0.4
Left kidney weight1.74.88.02.8-2.11.72.12.5-2.3-0.72.7-2.1
Right kidney weight2.46.812.93.0-2.22.03.03.6-2.6-0.23.2-2.0
Cocaine induced anxiety0.70.81.51.2-0.50.51.20.6-1.2-0.00.6-1.1
Post-drug Anxiety1.21.43.81.0-0.50.51.51.9-0.60.51.8-1.0
Baseline Anxiety0.30.31.5-0.80.2-0.1-0.10.41.20.2-0.00.3
Tail length0.20.72.2-0.90.8-1.30.50.00.41.50.3-0.2
Length with tail0.72.75.21.9-0.90.72.32.0-2.00.31.9-1.3
Length without tail3.47.414.63.8-2.62.62.72.8-3.3-1.52.5-1.9
Times rat made contact with spout0.20.20.8-0.60.0-0.3-0.6-0.40.9-0.1-0.4-0.0
Lifetime Intake2.32.65.2-1.81.4-1.6-1.9-2.31.20.5-1.81.5
Liver weight, left2.23.66.62.6-2.42.01.21.5-2.2-1.61.6-1.5
Liver weight, right1.11.84.41.1-2.11.60.30.7-0.6-2.10.5-1.4
Locomotor activity3.65.79.93.1-2.22.03.12.4-2.7-0.72.1-2.2
Locomotor testing distance1.11.86.21.4-0.30.12.51.2-1.60.91.1-1.2
Locomotor testing rearing2.03.010.21.20.7-0.73.21.5-1.72.41.7-0.9
Locomotion in novel chamber0.60.81.30.2-1.11.20.21.00.9-1.00.5-1.1
Locomotion in novel chamber post-restriction0.30.30.9-0.1-0.10.5-0.5-0.60.9-1.0-0.6-0.1
Fecal boli incidents, locomotor time 10.40.40.80.8-0.80.10.0-0.5-0.9-0.6-0.2-0.9
Change in fecal boli incidents, locomotor task0.40.30.90.30.3-0.20.40.9-0.40.71.00.5
Time >=10cm from walls, locomotor time 10.80.81.90.70.2-0.11.31.2-0.90.91.4-0.1
Bouts of movement, locomotor time 10.20.20.50.30.0-0.3-0.3-0.7-0.6-0.2-0.3-0.6
Total resting periods, locomotor time 10.40.41.7-0.20.2-0.4-1.1-1.3-0.1-0.3-0.9-0.2
Rest time, locomotor task time 10.50.51.5-0.6-0.10.3-1.2-0.90.6-0.9-1.00.1
Distance moved, locomotor task time 10.20.20.6-0.10.5-0.40.50.20.00.80.30.3
Vertical activity count, locomotor time 10.60.62.50.8-0.10.31.60.8-0.60.10.8-0.6
Time >=10cm from walls, locomotor time 20.60.61.20.50.5-0.41.00.6-1.10.91.00.6
Bouts of movement, locomotor time 20.80.83.20.9-1.81.1-0.50.2-0.3-1.3-0.2-0.5
Total resting periods, locomotor time 21.11.24.01.0-2.01.4-0.70.2-0.3-1.7-0.1-0.5
Rest time, locomotor task time 21.31.55.50.3-1.41.4-1.6-0.80.3-2.3-0.9-0.3
Distance moved, locomotor task time 20.40.51.3-0.61.1-0.80.90.20.21.10.00.2
Vertical activity count, locomotor time 20.20.21.3-0.30.5-0.11.10.10.30.3-0.1-0.3
Light reinforcement 10.40.72.5-1.20.5-0.3-0.7-0.11.60.0-0.51.0
Light reinforcement 20.81.12.3-1.30.6-0.8-1.5-0.71.50.1-0.61.5
Bone: marrow area0.10.10.3-0.20.6-0.50.1-0.50.10.3-0.4-0.1
Bone: maximum diameter0.40.81.9-0.2-0.80.7-0.8-0.90.8-1.3-1.4-0.7
Bone: maximum force0.81.33.90.4-1.71.6-0.2-0.10.4-2.0-0.8-1.2
Bone: maximum moment0.71.23.10.7-1.61.50.30.20.1-1.8-0.5-1.5
Mean time between licks in bursts1.82.57.8-1.52.2-2.50.0-0.50.72.80.10.8
Mean num. licks in bursts0.20.30.9-0.20.7-0.90.2-0.6-0.40.7-0.20.2
Cd content in liver0.30.31.00.30.1-0.70.50.1-0.51.00.5-0.2
Co content in liver0.80.92.7-0.1-1.20.9-1.1-0.60.8-1.6-1.0-0.4
Cu content in liver0.30.30.60.7-0.70.60.30.6-0.8-0.30.7-0.2
Fe content in liver0.80.92.8-0.11.2-1.10.30.2-0.71.70.71.3
K content in liver0.70.71.6-1.20.4-0.5-1.0-0.71.20.3-1.00.7
Mg content in liver0.80.81.4-1.20.7-1.0-0.9-0.91.10.7-0.90.2
Mn content in liver1.61.83.3-1.81.1-1.2-1.2-1.31.70.8-1.51.2
Na content in liver6.06.38.42.9-2.42.62.92.7-2.7-1.42.1-2.5
Rb content in liver0.60.82.2-0.51.3-1.3-0.4-0.40.21.50.21.0
Se content in liver0.50.62.00.50.4-0.11.40.6-1.11.20.4-0.1
Sr content in liver0.90.82.6-0.61.4-1.50.3-0.2-0.11.60.20.5
Zn content in liver2.52.84.81.9-1.41.22.21.8-1.8-0.21.8-1.8
Bone: minimum diameter0.30.61.70.2-1.10.80.1-0.50.1-1.0-1.0-1.3
Time in familiar zone, hab. session 11.00.91.8-1.10.6-0.4-1.1-1.21.2-0.2-1.40.8
Time in novel zone, hab. session 11.31.32.51.5-1.61.30.61.1-1.2-1.01.1-0.6
Total zone transitions, hab. session 10.30.41.6-0.2-0.30.8-0.1-0.40.7-1.3-0.9-0.4
Total locomotion distance, hab. session 10.30.41.4-0.60.20.2-0.1-0.60.9-0.5-1.20.3
Locomotion velocity, hab. session 10.20.30.8-0.60.40.20.4-0.20.9-0.3-0.90.0
Time in familiar zone, hab. session 20.30.31.1-0.60.4-0.4-0.8-0.30.60.3-0.21.1
Time in novel zone, hab. session 20.10.10.60.2-0.20.20.3-0.20.1-0.4-0.4-0.8
Total zone transitions, hab. session 20.30.40.90.5-0.70.70.90.3-0.2-0.80.0-0.9
Total locomotion distance, hab. session 20.10.10.4-0.1-0.10.40.1-0.30.4-0.6-0.7-0.1
Locomotion velocity, hab. session 20.20.20.80.1-0.40.70.3-0.10.3-0.9-0.6-0.4
Novel to familiar place preference ratio0.50.51.5-0.70.7-0.6-0.4-1.20.50.1-1.2-0.1
Novelty place preference0.40.41.0-0.60.7-0.6-0.2-1.00.30.3-1.0-0.2
Time in novel zone, NPP test0.20.20.6-0.40.5-0.4-0.0-0.80.10.2-0.8-0.4
Total zone transitions, NPP test0.10.10.4-0.5-0.10.00.3-0.10.6-0.1-0.6-0.3
Total locomotion distance, NPP test1.21.63.0-1.71.7-1.4-0.1-0.81.61.3-1.10.9
Locomotion velocity, NPP test1.31.83.3-1.81.6-1.4-0.3-1.01.71.2-1.21.0
Intraocular pressure1.11.53.8-1.21.9-1.7-0.0-0.80.61.9-0.40.6
Delta distance traveled before/after self-admin0.20.20.70.4-0.00.6-0.10.0-0.5-0.60.10.8
Delta ambulatory time before/after self-admin0.20.21.00.20.00.4-0.2-0.5-0.4-0.6-0.41.0
Parametrial fat weight3.05.89.8-3.11.9-2.4-2.3-2.82.51.3-2.82.0
Pavlov. Cond. lever latency0.50.61.2-1.10.8-1.0-0.8-0.61.00.4-0.20.6
Pavlov. Cond. magazine entry latency0.91.12.01.4-1.00.91.01.2-1.4-0.01.1-0.9
Pavlov. Cond. change in total contacts1.81.93.51.7-1.41.91.20.9-1.5-1.40.4-1.5
Pavlov. Cond. index score1.92.43.71.9-1.61.91.41.8-1.5-0.91.3-1.4
Pavlov. Cond. latency score1.51.93.11.7-1.41.61.31.5-1.5-0.61.0-1.3
Pavlov. Cond. lever contacts1.31.63.01.7-1.01.31.31.3-1.7-0.41.0-1.0
Pavlov. Cond. magazine entry number1.51.93.0-1.71.5-1.5-1.2-1.51.40.7-1.31.4
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.10.50.00.70.30.20.10.10.3
Pavlov. Cond. lever-magazine prob. diff.2.43.04.62.2-1.82.11.51.9-1.7-1.11.4-1.5
Pavlov. Cond. response bias2.22.64.42.1-1.71.81.31.8-1.7-0.91.5-1.5
Pavlov. Cond. lever latency2.23.05.1-2.21.2-1.1-2.2-1.82.30.4-2.01.6
Pavlov. Cond. magazine entry latency1.21.42.91.3-1.41.71.11.5-0.8-0.90.9-0.4
Pavlov. Cond. change in total contacts3.95.48.42.9-2.12.12.52.5-2.6-1.22.4-2.2
Pavlov. Cond. index score2.63.35.22.3-1.61.92.12.2-2.0-0.81.9-1.3
Pavlov. Cond. latency score2.73.35.12.3-1.51.72.32.3-2.0-0.62.0-1.3
Pavlov. Cond. lever contacts1.82.54.91.9-1.01.02.21.6-2.0-0.31.7-1.6
Pavlov. Cond. magazine entry number0.30.41.4-0.60.8-1.2-0.6-0.70.20.8-0.10.2
Pavlov. Cond. intertrial magazine entries5.77.514.1-3.33.7-3.8-1.4-2.42.33.1-1.71.7
Pavlov. Cond. lever-magazine prob. diff.2.33.04.52.1-1.51.92.02.1-1.8-0.91.7-1.1
Pavlov. Cond. response bias1.92.63.81.9-1.71.61.91.6-1.7-0.91.3-1.6
Time in closed arm before self-admin2.42.74.81.5-1.82.01.22.2-0.9-1.21.7-1.9
Time in closed arm after self-admin0.60.61.60.7-0.41.11.01.3-0.40.00.9-0.1
Time in open arm before self-admin0.91.01.7-1.11.3-1.2-0.3-1.31.00.6-1.00.8
Time in open arm after self-admin0.40.41.3-0.70.9-1.1-0.4-0.20.50.70.10.5
Bone: periosteal estimation0.20.41.0-0.3-0.30.3-0.4-0.70.7-0.8-1.0-0.7
Bone: periosteal perimeter0.10.20.8-0.50.3-0.0-0.2-0.60.7-0.1-0.9-0.4
Bone: post-yield work3.85.210.6-2.3-0.30.1-3.1-2.73.2-1.9-3.30.6
Progressive ratio test 1 active lever presses1.61.64.3-1.30.3-0.4-2.1-1.71.4-0.8-1.60.8
Progressive ratio test 1 breakpoint1.71.74.8-1.30.2-0.3-2.2-1.71.3-0.9-1.70.9
Progressive ratio test 1 inactive lever presses0.60.71.2-1.11.0-1.1-0.6-0.50.50.8-0.41.0
Progressive ratio test 2 active lever presses2.12.34.8-1.71.4-1.8-1.7-2.21.20.8-1.50.7
Progressive ratio test 2 breakpoint1.41.63.3-1.41.2-1.6-1.4-1.81.00.7-1.20.7
Progressive ratio test 2 inactive lever presses1.11.32.4-1.31.5-1.6-0.7-1.10.61.3-0.60.9
Incentive Sensitization - Responses1.01.03.3-0.71.5-1.80.2-1.00.11.5-0.1-0.0
Incentive Sensitization - Breakpoint1.11.13.5-0.71.5-1.90.3-0.90.11.60.0-0.1
Sum of active levers in priming session hrs 5-61.21.22.2-1.50.9-0.8-1.3-0.81.40.1-0.91.4
Progressive ratio1.21.42.71.4-1.10.81.41.5-0.9-0.71.6-0.8
Food seeking constrained by brief footshock0.70.84.0-0.60.4-0.3-1.4-0.60.5-0.0-0.52.0
Seeking ratio, punishment vs. effort0.81.02.2-0.90.7-0.4-1.5-1.20.40.3-1.21.4
Retroperitoneal fat weight0.62.03.6-1.40.8-1.2-1.8-1.91.00.4-1.91.5
Reaction time number correct0.20.30.8-0.40.8-0.9-0.2-0.30.40.60.10.6
Reaction time mean minus median1.11.52.41.5-1.10.91.41.4-1.4-0.21.4-1.2
Reaction time mean minus median AUC0.70.91.90.9-0.60.41.21.4-0.80.11.4-0.8
Reaction time num false alarms0.50.72.20.4-0.70.81.11.5-0.1-0.41.0-0.4
Reaction time num false alarms AUC0.40.61.50.5-0.80.81.01.2-0.1-0.50.8-0.5
Reaction time trials correct on left0.20.30.8-0.40.8-0.9-0.2-0.30.40.60.10.6
Reaction time trials on left0.30.41.0-0.50.9-1.0-0.2-0.40.40.70.10.7
Reaction time mean0.70.92.11.1-0.2-0.21.10.9-1.40.71.5-0.7
Reaction time mean AUC1.21.63.41.4-0.4-0.01.51.3-1.70.71.8-1.0
Median of all reaction times0.50.71.60.70.2-0.60.80.6-1.21.01.3-0.3
Reaction time omissions1.11.54.9-0.81.8-2.00.2-0.10.32.20.50.7
Reaction time false alarm rate0.50.71.50.5-1.11.20.71.2-0.1-0.90.6-0.5
Reaction time premature initiation rate0.30.40.90.9-0.90.8-0.00.2-0.9-0.80.0-0.4
Reaction time premature initiations0.10.10.30.5-0.30.2-0.2-0.2-0.5-0.4-0.00.0
Std. dev. reaction times0.40.51.10.9-0.40.10.80.7-1.00.21.0-0.8
Reaction time trials completed0.30.41.0-0.50.9-1.0-0.2-0.40.40.70.10.7
Reaction time trials AUC0.30.51.2-0.51.1-1.1-0.2-0.50.40.80.00.8
Run reversals in cocaine runway, females0.70.72.0-1.41.0-0.0-0.6-0.21.3-0.1-0.40.8
Run reversals in cocaine runway, males1.71.74.21.4-1.91.80.40.5-1.0-2.10.2-1.0
Latency to leave start box in cocaine runway0.70.72.0-0.21.3-1.4-0.1-1.0-0.41.3-0.20.3
Latency to leave start box in cocaine runway, F0.30.30.90.50.6-0.60.4-0.3-1.00.70.30.1
Latency to leave start box in cocaine runway, M0.90.83.3-0.51.3-1.40.2-0.20.01.80.4-0.5
Std. dev. time between licks in bursts0.81.04.2-0.51.1-1.50.9-0.1-0.12.1-0.0-0.4
Total sessions with >9 infusions0.91.02.2-1.11.1-1.5-0.7-0.61.01.3-0.20.9
Short access day 1 total inactive lever presses0.60.61.7-0.70.7-0.8-1.3-1.10.00.0-0.70.7
Short access day 10 total inactive lever presses0.70.71.5-1.20.9-0.9-0.7-0.41.20.8-0.50.8
Short access day 1 total infusions2.32.54.6-1.51.9-2.1-1.6-1.90.71.3-1.01.5
Short access day 10 total infusions1.01.13.0-1.00.00.0-1.2-1.51.3-0.9-1.70.2
Short access total infusions0.70.81.8-0.90.7-1.0-1.0-1.30.60.4-1.00.8
Short access day 1 locomotion0.20.20.60.20.1-0.40.60.3-0.60.80.40.5
Short access day 10 total locomotion0.40.51.70.4-0.90.60.61.30.1-0.10.8-0.2
Short access total locomotion0.30.31.20.2-0.50.30.61.1-0.10.30.80.1
One hour access (0.3 mA shock)1.82.24.4-1.70.6-0.9-1.7-2.11.6-0.2-2.10.9
Compulsive drug intake0.70.73.5-1.1-0.20.3-0.6-0.21.9-0.8-0.9-0.3
One hour access (shock baseline)1.21.43.8-1.01.0-1.4-1.3-1.90.30.5-1.41.0
Social response proportion1.71.93.9-0.81.7-2.0-1.2-1.40.11.7-0.51.7
Social responses2.32.95.8-1.42.2-2.3-0.8-1.40.62.4-1.02.0
Social time0.91.22.70.60.6-0.51.61.3-1.11.21.6-0.2
Soleus weight0.20.61.70.2-1.21.0-0.60.10.4-1.3-0.4-0.4
Bone: stiffness0.40.61.80.4-1.41.2-0.10.40.2-1.1-0.1-0.6
Tibialis anterior weight4.716.128.54.4-5.05.32.53.8-2.9-4.82.8-3.5
Time to tail flick, vehicle, before self-admin1.01.02.90.8-1.11.70.71.6-0.2-0.90.8-0.3
Time to tail flick, vehicle, after self-admin1.21.22.61.1-1.51.60.20.8-0.6-1.30.6-1.4
Time to tail flick, test, before self-admin0.50.52.1-0.0-0.50.40.60.80.6-0.70.6-1.5
Time to tail flick, test, after self-admin3.33.57.2-2.22.7-2.2-1.2-1.12.21.9-0.61.7
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.00.3-0.6-0.6-0.9-0.40.2-0.2-0.4
Delta time to tail flick, test, before/after SA4.23.86.7-2.12.5-2.2-1.7-1.51.42.0-0.92.6
Tibia length1.74.710.92.1-0.51.33.33.2-2.40.72.8-0.9
Ambulatory time before self-admin0.20.20.5-0.30.0-0.1-0.1-0.50.4-0.4-0.5-0.7
Ambulatory time after self-admin0.20.21.00.4-0.60.70.2-0.2-0.4-1.0-0.2-0.1
Bone: tissue strength0.20.10.5-0.30.0-0.70.5-0.00.20.60.1-0.2
Total heroin consumption0.40.51.30.8-0.90.90.40.2-0.6-0.80.1-1.1
Bone: trabecular number0.60.92.3-1.11.5-1.3-0.0-0.10.91.3-0.00.9
Bone: trabecular spacing1.11.54.00.9-2.01.9-0.10.4-0.2-2.0-0.2-0.9
Bone: trabecular thickness0.20.20.6-0.2-0.10.70.10.50.8-0.8-0.2-0.3
Bone: trabecular tissue density1.21.64.01.4-1.62.00.71.4-0.8-1.50.8-0.6
Water consumed over 24 hours0.81.01.81.0-1.21.10.80.9-0.6-0.90.8-1.4
Number of responses in last shaping day0.30.31.30.8-0.40.10.80.1-1.10.10.2-0.5