Fzd3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	Fzd3	0.06	0.04	1.2e-05	0.06	0.05	0.06	0.05	1.1e-06	3.1e-05	6.9e-06	8.9e-06
2	pVTA	gene expression	Fzd3	0.05	0.03	2.4e-05	0.06	0.06	0.07	0.06	8.4e-06	7.6e-06	3.5e-06	1.9e-05
3	NAcc	mRNA stability	Fzd3	0.05	0.02	4.5e-08	0.05	0.05	0.07	0.05	1.1e-08	3.4e-08	3.3e-10	1.1e-07
4	IL	mRNA stability	Fzd3	0.45	0.14	2.1e-08	0.14	0.19	0.17	0.2	3.5e-04	2.4e-05	6.9e-05	1.4e-05
5	Adipose	gene expression	Fzd3	0.03	0.02	3.6e-03	0.02	0.01	0.01	0.01	2.0e-03	7.5e-03	8.6e-03	8.2e-03
6	RMTg	gene expression	Fzd3	0.17	0.09	4.3e-03	0.06	0.06	0.09	0.09	9.3e-03	1.3e-02	2.5e-03	1.8e-03
7	LHb	mRNA stability	Fzd3	0.18	0.11	5.9e-03	0.05	0.1	0.08	0.08	2.6e-02	2.5e-03	5.8e-03	5.8e-03
8	OFC	mRNA stability	Fzd3	0.25	0.12	1.1e-04	0.14	0.09	0.13	0.11	4.2e-04	4.1e-03	6.1e-04	1.3e-03
9	Brain	mRNA stability	Fzd3	0.31	0.12	0.0e+00	0.28	0.28	0.27	0.27	6.0e-26	6.9e-26	9.0e-25	1.3e-25
10	PL	mRNA stability	Fzd3	0.06	0.03	6.8e-06	0.05	0.05	0.06	0.05	1.9e-06	1.3e-06	8.7e-07	1.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.5	1.0	1.8	1.2	1.1	0.9	-1.0	-1.2	-1.3	-0.1	1.3	0.2	0.0
Area under the delay curve	2.1	3.2	8.8	-2.8	-1.4	-1.9	1.6	2.6	3.0	-0.0	0.3	-0.7	0.5
BMI with tail	0.2	0.7	2.3	-1.5	-0.6	-0.6	0.9	1.2	1.3	-0.2	0.1	-0.8	-0.2
BMI without tail	0.1	0.3	0.7	0.1	0.6	0.8	-0.2	-0.2	-0.2	-0.9	0.8	-0.0	0.2
Body weight	0.8	3.6	5.8	-2.4	-1.9	-2.0	2.2	2.0	1.7	1.5	-0.9	-2.4	-1.5
Weight adjusted by age	1.5	4.4	9.7	-1.3	-2.5	-1.9	2.1	1.3	0.7	2.6	-3.1	-2.1	-2.3
Bone surface	0.3	0.5	1.2	1.0	0.6	0.5	-0.8	-1.0	-1.1	0.3	0.8	0.1	-0.1
Bone volume	0.2	0.5	1.7	0.7	0.7	0.5	-0.8	-0.7	-0.6	-0.0	1.3	0.4	0.4
Breakpoint value in progressive ratio session	0.3	0.6	1.8	-1.1	-0.3	-0.7	0.6	1.0	1.3	-0.3	0.4	-0.1	0.4
Number of licking bursts	0.1	0.3	0.9	-0.7	0.1	0.0	0.1	0.7	0.8	-0.8	0.9	0.2	0.3
Context. condit. distance diff. score	4.0	4.9	10.2	1.3	2.5	2.7	-2.3	-1.2	-0.6	-3.2	2.3	2.4	2.3
Locomotion velocity, session 1	0.1	0.1	0.7	-0.4	-0.0	-0.4	0.0	0.4	0.4	0.2	0.9	-0.1	0.2
Locomotion distance, session 1	0.1	0.1	0.7	-0.1	-0.3	-0.6	-0.0	0.1	-0.1	0.9	0.3	0.0	-0.0
Locomotion velocity, session 2	0.1	0.2	0.4	-0.5	-0.3	-0.6	0.0	0.4	0.5	0.4	0.5	0.2	0.4
Locomotion distance, session 2	0.2	0.3	1.4	0.2	-0.1	-0.8	-0.0	-0.3	-0.5	1.2	0.5	-0.1	-0.2
Locomotion velocity, session 3	0.7	0.8	1.8	-0.9	-0.8	-0.5	1.2	1.0	0.8	0.5	-0.6	-1.3	-0.9
Locomotion distance, session 3	0.2	0.3	0.8	-0.8	-0.2	-0.1	0.5	0.8	0.9	-0.3	0.3	-0.4	-0.0
Stereotopy head waving bouts, day 3	0.8	1.0	3.5	0.3	-0.8	-0.6	0.7	-0.4	-0.8	1.2	-1.9	-0.9	-1.4
Stereotopy head waving duration, day 3	1.3	1.6	3.3	-0.7	-1.4	-1.2	1.5	0.6	0.3	1.4	-1.8	-1.3	-1.3
Locomotion velocity, session 7	4.1	4.5	10.3	1.2	2.6	2.3	-2.1	-1.2	-0.7	-3.2	2.5	2.1	2.0
Locomotion distance, session 7	5.0	6.4	11.2	1.8	3.2	2.7	-2.6	-1.8	-1.3	-3.1	3.3	2.3	2.2
Stereotopy head waving bouts, day 7	1.9	2.2	3.2	-1.2	-1.7	-1.7	1.8	1.2	1.0	1.6	-1.5	-1.6	-1.4
Stereotopy head waving duration, day 7	3.5	4.3	6.4	-1.7	-2.4	-2.1	2.5	1.7	1.3	2.0	-2.5	-2.2	-2.0
Locomotion velocity, session 8	0.3	0.4	0.9	-0.2	0.5	0.6	-0.4	0.2	0.5	-0.9	1.0	0.7	0.9
Locomotion distance, session 8	1.2	1.8	4.2	0.8	1.5	1.2	-1.4	-0.8	-0.4	-1.5	2.1	1.4	1.5
Degree of sensitization distance	7.7	8.3	11.5	2.6	3.4	3.0	-3.3	-2.6	-2.2	-2.9	2.9	3.1	2.5
Degree of sensitization stereotypy	1.2	1.3	1.9	-1.3	-1.4	-1.3	1.4	1.3	1.3	0.8	-0.8	-0.9	-0.6
Conditioned locomotion	0.9	1.1	1.6	0.9	1.1	1.3	-1.1	-0.9	-0.7	-1.2	0.8	1.2	1.0
Cocaine response after cond. corrected	1.0	1.5	3.9	0.2	1.3	1.2	-1.0	-0.2	0.2	-2.0	1.7	1.2	1.6
Cocaine response after cond. not corrected	1.0	1.4	4.4	-0.1	1.2	1.0	-0.8	0.0	0.4	-1.7	2.1	1.0	1.4
Cocaine response before conditioning	0.5	0.6	1.4	-0.5	-0.6	-1.0	0.7	0.5	0.2	1.2	0.0	-0.9	-1.0
Saline control response	0.5	0.7	1.7	-0.2	-0.9	-0.9	0.6	0.2	-0.1	1.3	-1.1	-0.8	-0.9
Bone: connectivity density	1.2	1.9	5.5	2.0	1.3	1.2	-1.1	-1.9	-2.3	0.1	0.7	-0.2	-0.9
Bone: cortical apparent density	0.2	0.2	0.6	-0.7	0.0	0.2	0.3	0.7	0.8	-0.7	0.4	-0.2	0.2
Bone: cortical area	0.5	0.8	2.3	-1.3	-0.7	-0.7	0.3	1.3	1.5	0.0	0.7	0.3	0.8
Bone: cortical porosity	1.4	1.5	2.3	-1.5	-1.5	-1.4	1.2	1.5	1.4	1.0	-0.9	-0.8	-0.5
Bone: cortical porosity	1.7	1.8	2.9	-1.4	-1.7	-1.6	1.4	1.4	1.3	1.4	-1.3	-1.0	-0.8
Bone: cortical thickness	0.9	1.4	4.7	-1.9	-0.9	-0.8	0.7	1.9	2.2	-0.3	0.5	0.1	0.7
Bone: cortical thickness	2.2	2.7	6.0	-1.4	0.5	0.4	-0.7	1.4	2.1	-2.1	2.1	1.7	2.5
Bone: cortical tissue density	0.1	0.2	0.6	-0.6	0.1	0.3	0.2	0.6	0.7	-0.8	0.5	-0.2	0.2
Condit. Reinf. active minus inactive responses	0.6	0.6	1.2	-0.5	-1.0	-1.1	0.8	0.6	0.4	1.0	-1.0	-0.6	-0.7
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.5	0.1	-0.3	-0.2	0.3	-0.1	-0.3	0.3	-0.7	-0.2	-0.4
Condit. Reinf. active responses	0.6	0.7	1.9	-0.7	-1.0	-1.4	0.8	0.8	0.6	1.1	-0.6	-0.6	-0.7
Condit. Reinf. inactive responses	0.3	0.4	1.3	-0.5	-0.7	-1.1	0.4	0.6	0.4	1.0	-0.1	-0.5	-0.6
Incentive salience index mean	1.7	2.2	3.7	-1.5	-1.8	-1.9	1.4	1.5	1.3	1.5	-1.3	-1.1	-1.1
Condit. Reinf. lever presses	1.7	2.5	4.1	-1.9	-1.9	-2.0	1.4	1.9	1.8	1.5	-0.8	-1.2	-0.9
Condit. Reinf. active minus inactive responses	0.2	0.3	0.7	0.4	0.4	0.2	-0.7	-0.5	-0.4	-0.3	0.3	0.9	0.7
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.3	0.3	0.3	0.2	-0.3	-0.3	-0.2	-0.4	-0.0	0.5	0.4
Condit. Reinf. active responses	0.3	0.4	0.8	0.6	0.6	0.3	-0.8	-0.7	-0.6	-0.4	0.7	0.9	0.8
Condit. Reinf. inactive responses	0.7	1.0	1.5	1.0	1.1	0.7	-1.2	-1.1	-1.0	-0.5	1.2	1.0	0.8
Condit. Reinf. lever presses	0.4	0.5	1.7	0.1	-0.6	-0.7	0.5	-0.2	-0.5	1.3	-0.8	-0.8	-0.9
Condit. Reinf. lever reinforcers received	0.1	0.2	0.4	0.3	0.3	0.0	-0.5	-0.4	-0.3	-0.2	0.4	0.6	0.5
Conditioned reinforcement - actives	1.2	4.6	6.7	2.6	2.4	2.3	-2.5	-2.5	-2.4	-1.4	1.8	1.7	1.3
Conditioned reinforcement - inactives	0.4	1.2	2.8	1.6	1.1	1.0	-1.2	-1.4	-1.7	-0.2	0.9	0.2	-0.4
Conditioned locomotion	1.5	2.3	3.6	0.8	1.7	1.6	-1.8	-0.9	-0.5	-1.9	1.6	1.7	1.9
Patch foraging indifference point 0 sec	0.4	1.2	4.1	-0.2	-1.0	-1.8	0.7	0.0	-0.2	2.0	-0.7	-1.1	-1.2
Patch foraging indifference point AUC	0.6	1.5	3.2	0.4	1.1	1.7	-1.0	-0.2	0.4	-1.7	1.2	1.4	1.8
Delay disc. indifference point, 0s delay	0.1	0.1	0.8	-0.3	-0.2	-0.9	0.0	-0.2	0.1	0.6	-0.2	-0.1	-0.1
Delay disc. indifference point, 16s delay	1.2	1.7	5.4	-1.8	-0.6	-0.6	0.7	1.9	2.3	-0.7	1.5	0.2	1.0
Delay disc. indifference point, 2s delay	0.7	0.7	2.4	-1.1	-0.8	-1.6	0.6	0.8	0.9	0.8	-0.5	-0.5	-0.1
Delay disc. indifference point, 24s delay	1.3	2.0	5.6	-1.9	-0.3	-0.6	0.4	1.8	2.4	-1.1	1.8	0.5	1.5
Delay disc. indifference point, 4s delay	2.7	2.9	6.0	-2.3	-1.7	-1.9	1.8	2.2	2.5	0.6	-1.0	-1.1	-0.3
Delay disc. indifference point, 8s delay	1.9	3.2	7.8	-2.8	-1.4	-2.0	1.9	2.5	2.8	-0.0	0.1	-0.9	0.2
Indifference point function ln k	0.5	1.5	3.3	-0.8	-1.2	-1.8	1.2	0.6	0.3	1.6	-1.2	-1.3	-1.4
Indifference point function log k	0.5	1.5	3.3	-0.8	-1.2	-1.8	1.2	0.6	0.3	1.6	-1.2	-1.3	-1.4
Patch foraging total patch changes 0 sec	0.6	1.7	4.7	-0.6	-1.3	-2.1	1.0	0.4	0.2	2.2	-1.0	-1.3	-1.3
Patch foraging total patch changes 12 sec	0.1	0.1	0.3	-0.5	-0.3	-0.4	0.1	0.5	0.5	0.4	0.4	-0.1	0.1
Patch foraging total patch changes 18 sec	0.2	0.4	0.8	0.4	0.5	0.7	-0.9	-0.3	-0.2	-0.4	0.8	0.7	0.8
Patch foraging total patch changes 24 sec	0.1	0.3	1.0	-0.2	-0.7	-0.8	0.4	0.3	0.4	1.0	-0.2	-0.4	-0.2
Patch foraging total patch changes 6 sec	0.0	0.0	0.1	-0.1	-0.2	-0.3	0.2	0.0	0.2	0.2	0.3	-0.2	-0.1
Patch foraging time to switch 0 sec	0.0	0.2	0.3	0.2	0.6	0.1	-0.6	-0.3	-0.5	-0.4	0.5	0.3	0.1
Patch foraging water rate 0 sec	0.3	1.1	1.6	-1.1	-1.3	-1.1	1.2	1.2	1.2	1.0	-0.7	-1.0	-0.7
Patch foraging water rate 12 sec	0.3	1.0	3.3	-0.4	-1.3	-1.0	0.9	0.8	0.5	1.2	-1.8	-0.6	-0.8
Patch foraging water rate 18 sec	1.6	3.7	6.2	-2.2	-2.1	-1.9	2.5	2.1	2.1	1.2	-1.6	-1.9	-1.0
Patch foraging water rate 24 sec	0.1	0.1	0.4	-0.1	-0.2	0.2	-0.0	0.3	0.2	-0.3	-0.6	0.4	0.3
Patch foraging water rate 6 sec	1.3	1.9	2.9	-1.0	-1.7	-1.4	1.5	1.1	1.0	1.7	-1.7	-1.3	-0.9
Seeking ratio, delayed vs. immediate footshock	0.1	0.2	0.6	0.1	-0.2	-0.5	-0.1	-0.1	-0.4	0.6	-0.1	-0.4	-0.8
Distance traveled before self-admin	0.2	0.4	1.2	0.4	-0.6	-0.6	0.5	-0.3	-0.3	1.1	-1.0	-0.4	-0.4
Distance traveled after self-admin	0.2	0.4	0.8	-0.6	-0.9	-0.8	0.7	0.7	0.6	0.8	-0.5	-0.3	0.0
Extensor digitorum longus weight	4.8	19.1	31.4	-5.6	-5.0	-4.1	5.1	5.6	5.4	2.5	-3.0	-3.6	-1.7
Bone: elastic displacement	0.2	0.2	0.7	0.5	-0.3	-0.3	-0.2	-0.5	-0.6	0.8	-0.6	0.1	-0.2
Bone: elastic work	0.8	1.0	2.7	-0.7	-1.3	-1.4	0.9	0.7	0.5	1.7	-0.7	-0.8	-0.8
Bone: endosteal estimation	0.1	0.1	0.3	0.5	0.2	0.1	-0.3	-0.5	-0.6	0.4	0.5	0.0	0.0
Bone: endosteal perimeter	0.2	0.6	1.7	1.2	0.3	0.1	-0.5	-1.2	-1.3	0.8	0.1	0.2	-0.1
Epididymis fat weight	0.0	0.2	0.4	-0.4	-0.0	-0.3	-0.0	0.2	0.6	-0.4	0.3	0.5	0.7
Delta time in closed arm before/after self-admin	0.6	0.5	1.2	0.9	0.7	0.7	-1.1	-0.7	-0.9	-0.4	0.7	0.5	0.1
Delta time in open arm before/after self-admin	0.2	0.3	0.6	-0.8	-0.6	-0.3	0.6	0.4	0.5	0.1	-0.3	-0.7	-0.4
Diff in mean of infusions in LGA sessions	3.5	6.2	9.0	-2.8	-2.6	-3.0	2.8	2.5	2.1	1.9	-2.2	-2.6	-2.2
Delay discount exponential model param	2.8	3.9	10.0	3.1	1.6	2.1	-1.8	-2.8	-3.2	-0.1	-0.1	0.9	-0.4
Extinction: sum of active levers before priming	0.1	0.2	0.4	-0.5	-0.1	-0.5	0.2	0.6	0.5	0.1	0.5	-0.4	-0.2
Active lever presses in extinction session 6	1.0	1.0	1.8	0.6	1.2	1.1	-1.0	-0.5	-0.3	-1.3	0.8	1.3	1.2
Bone: final force	0.5	0.8	2.4	-1.4	-0.8	-0.7	0.6	1.4	1.5	0.2	0.3	-0.2	0.3
Bone: final moment	0.5	0.8	1.8	-1.3	-1.0	-1.0	0.8	1.3	1.3	0.7	-0.1	-0.5	-0.1
Food consumed during 24 hour testing period	0.2	0.4	1.1	-0.0	-0.7	-0.5	0.6	-0.0	-0.2	1.0	-0.8	-0.6	-0.6
Glucose	0.3	0.5	1.3	-0.6	0.2	0.4	-0.1	0.6	0.9	-1.1	0.5	0.8	1.1
Heart weight	0.1	0.1	0.3	0.4	0.1	-0.2	0.0	-0.5	-0.5	-0.0	-0.4	0.1	-0.2
Delay discount hyperbolic model param	2.6	3.4	8.6	2.8	1.6	2.1	-1.7	-2.6	-2.9	-0.2	0.1	0.8	-0.3
Intermittent access intake day 1-15 change	0.2	1.3	2.1	1.4	1.3	1.2	-1.4	-1.2	-1.4	-0.5	0.5	1.1	0.7
Intermittent access intake escalation	0.1	0.6	1.2	1.0	0.8	0.8	-1.0	-0.8	-1.1	-0.2	0.2	0.7	0.4
Intermittent access intake escalation 2	0.1	0.2	0.6	0.6	0.3	0.4	-0.4	-0.4	-0.8	-0.1	-0.5	0.3	0.1
Intermitt. access day 1 inactive lever presses	0.1	0.7	1.6	1.2	0.9	0.9	-0.9	-1.0	-1.3	-0.5	0.1	0.4	-0.5
Intermitt. access day 15 inactive lever presses	0.1	0.6	2.3	0.5	-0.4	0.2	0.6	-0.0	-0.4	0.6	-1.4	-0.9	-1.5
Intermitt. access escalation Index	0.1	0.2	0.6	0.2	0.4	-0.0	-0.5	-0.4	-0.4	-0.3	0.7	0.3	0.4
Intermittent access day 1 total infusions	0.3	0.9	1.9	0.6	1.0	0.9	-1.2	-0.8	-0.5	-0.9	1.4	0.9	1.2
Intermittent access day 15 total infusions	0.9	2.2	3.4	1.6	1.7	1.6	-1.9	-1.6	-1.5	-1.2	1.1	1.4	1.2
Intermittent access terminal intake (last 3 days)	1.4	2.4	3.7	1.6	1.7	1.9	-1.8	-1.6	-1.5	-1.4	0.8	1.5	1.4
Intermittent access total infusions	3.2	3.8	5.6	1.9	2.2	2.3	-2.4	-1.8	-1.5	-1.9	1.7	2.0	1.8
Intermittent access day 1 locomotion	0.1	0.2	0.8	-0.6	-0.1	-0.6	0.1	0.4	0.5	-0.2	0.9	-0.4	0.1
Intermittent access day 15 total locomotion	0.1	0.4	0.7	0.5	0.7	0.9	-0.8	-0.6	-0.7	-0.6	-0.1	0.5	0.5
Intermittent access total locomotion	0.1	0.1	0.2	0.1	0.3	0.2	-0.5	-0.3	-0.4	-0.5	0.1	0.1	0.3
Intermittent access standard deviation	0.2	0.9	1.6	1.1	0.4	1.1	-0.9	-1.0	-0.8	-0.3	-1.3	1.1	1.0
Left kidney weight	0.5	3.8	6.4	-1.7	-1.9	-2.2	2.3	1.5	0.9	1.9	-1.9	-2.5	-2.2
Right kidney weight	1.0	7.3	13.2	-2.1	-2.7	-3.0	2.9	1.9	1.1	3.0	-2.5	-3.6	-3.4
Cocaine induced anxiety	0.7	1.8	3.6	-1.2	-1.5	-1.9	1.5	1.2	1.0	1.3	-1.3	-1.1	-1.1
Post-drug Anxiety	1.9	2.1	4.9	-0.8	-1.4	-2.2	1.8	0.8	0.4	1.7	-0.9	-1.6	-1.8
Baseline Anxiety	0.1	0.2	1.2	0.1	0.4	-0.1	0.2	-0.2	-0.2	-0.2	1.1	-0.4	-0.2
Tail length	0.1	0.7	2.0	0.6	-0.2	-0.3	0.3	-0.5	-1.1	1.2	-0.6	-1.1	-1.4
Length with tail	0.6	2.9	5.5	-0.9	-1.6	-2.0	1.7	0.8	0.2	2.4	-1.6	-2.1	-2.2
Length without tail	1.2	6.1	9.2	-2.7	-2.8	-3.0	2.7	2.4	2.1	2.4	-2.0	-2.4	-1.9
Times rat made contact with spout	0.1	0.2	0.2	0.3	0.5	0.5	-0.3	-0.3	-0.2	-0.5	0.5	0.4	0.4
Lifetime Intake	2.8	3.5	5.1	1.9	2.1	2.1	-2.3	-1.8	-1.5	-1.7	1.6	1.9	1.8
Liver weight, left	2.3	4.1	6.1	-1.4	-2.4	-2.2	2.1	1.3	0.8	2.4	-2.5	-2.3	-2.1
Liver weight, right	0.9	1.5	3.2	-1.8	-1.2	-1.1	1.5	1.7	1.8	0.3	-0.2	-1.0	-0.1
Locomotor activity	4.6	7.2	11.2	-2.0	-3.2	-3.3	2.8	2.0	1.6	3.3	-2.9	-2.6	-2.6
Locomotor testing distance	0.9	2.2	6.9	0.1	-1.5	-1.9	1.0	0.0	-0.4	2.6	-1.6	-1.2	-1.9
Locomotor testing rearing	0.9	3.5	11.3	0.7	-1.3	-2.1	1.0	-0.6	-1.4	3.4	-1.7	-1.9	-2.6
Locomotion in novel chamber	0.3	0.5	1.5	-0.7	-0.3	-0.4	0.7	0.9	0.5	0.1	1.2	-0.8	-0.5
Locomotion in novel chamber post-restriction	0.1	0.4	1.0	-0.7	-0.0	0.8	-0.6	0.6	0.8	-0.5	0.6	0.5	1.0
Fecal boli incidents, locomotor time 1	0.1	0.2	0.5	-0.6	-0.5	-0.5	0.3	0.1	0.1	0.2	-0.7	-0.2	0.5
Change in fecal boli incidents, locomotor task	0.1	0.1	0.8	0.3	-0.1	0.2	0.2	-0.2	-0.2	0.1	-0.2	-0.4	-0.9
Time >=10cm from walls, locomotor time 1	0.6	0.8	2.4	-0.0	-0.7	-0.5	0.7	0.0	-0.3	1.2	-1.2	-1.1	-1.5
Bouts of movement, locomotor time 1	0.2	0.2	1.1	-0.1	-0.1	0.3	-0.4	-0.3	-0.1	-0.3	-1.0	0.5	0.5
Total resting periods, locomotor time 1	0.5	0.6	1.5	0.1	0.4	0.9	-0.9	-0.5	-0.1	-1.1	-0.4	1.1	1.2
Rest time, locomotor task time 1	0.7	1.2	2.5	0.3	1.2	1.2	-1.0	-0.2	0.1	-1.6	1.1	1.3	1.5
Distance moved, locomotor task time 1	0.1	0.2	0.5	0.4	0.0	-0.1	0.2	-0.2	-0.3	0.6	-0.6	-0.3	-0.7
Vertical activity count, locomotor time 1	0.2	1.4	3.7	-0.5	-1.3	-1.1	1.1	0.7	0.4	1.9	-1.3	-1.4	-1.4
Time >=10cm from walls, locomotor time 2	0.1	0.3	0.9	0.5	-0.2	-0.1	0.5	-0.3	-0.4	0.9	-0.7	-0.6	-0.9
Bouts of movement, locomotor time 2	0.3	1.0	2.5	-1.6	-0.8	-0.8	1.0	1.3	1.6	-0.3	-0.5	-0.3	0.4
Total resting periods, locomotor time 2	0.3	1.2	3.4	-1.8	-0.8	-0.7	1.1	1.5	1.8	-0.5	-0.6	-0.3	0.5
Rest time, locomotor task time 2	0.8	1.3	3.3	-1.3	0.0	0.5	0.1	1.3	1.8	-1.6	0.2	0.7	1.7
Distance moved, locomotor task time 2	0.3	0.4	0.9	0.9	0.2	-0.1	-0.2	-0.8	-0.8	0.9	0.2	-0.1	-0.7
Vertical activity count, locomotor time 2	0.2	0.4	2.0	0.2	-0.4	-0.7	0.2	0.0	-0.1	1.4	0.5	-0.5	-0.7
Light reinforcement 1	0.0	0.2	0.6	0.3	0.6	0.3	-0.3	-0.1	-0.1	-0.5	0.8	0.3	0.1
Light reinforcement 2	0.5	1.1	2.3	0.8	1.3	1.5	-0.9	-0.7	-0.4	-1.5	1.0	0.9	0.9
Bone: marrow area	0.1	0.2	0.4	0.6	0.3	0.2	-0.4	-0.6	-0.6	0.3	0.6	0.1	0.2
Bone: maximum diameter	0.2	0.4	1.1	-0.7	-0.2	-0.2	0.0	0.7	1.0	-0.3	0.7	0.6	1.1
Bone: maximum force	0.6	1.3	3.7	-1.6	-1.0	-1.0	0.7	1.7	1.9	0.4	0.6	-0.2	0.6
Bone: maximum moment	0.7	1.3	3.0	-1.6	-1.3	-1.3	1.0	1.6	1.7	0.9	0.2	-0.5	0.1
Mean time between licks in bursts	0.4	2.4	7.0	2.3	1.6	1.0	-1.3	-2.3	-2.6	0.0	0.7	0.3	-0.5
Mean num. licks in bursts	0.1	0.3	0.8	0.9	0.3	0.4	-0.4	-0.9	-0.9	0.3	-0.5	0.2	0.1
Cd content in liver	2.2	2.4	4.9	-0.5	-1.6	-1.5	1.6	0.4	-0.0	2.2	-2.1	-1.9	-1.9
Co content in liver	0.5	0.6	1.6	-1.1	-0.7	-0.3	0.6	1.1	1.2	-0.2	-0.6	0.0	0.5
Cu content in liver	0.3	0.3	0.7	-0.8	-0.5	-0.5	0.8	0.8	0.7	0.1	-0.3	-0.6	-0.3
Fe content in liver	0.5	0.6	1.8	1.2	0.7	0.2	-0.5	-1.2	-1.3	0.1	-0.4	0.0	-0.5
K content in liver	0.6	0.6	1.3	0.6	1.1	1.0	-0.8	-0.6	-0.6	-1.0	1.0	0.5	0.3
Mg content in liver	1.5	1.6	2.8	1.6	1.6	1.0	-1.1	-1.6	-1.7	-0.7	1.2	0.9	0.5
Mn content in liver	1.2	1.3	2.2	1.2	1.4	0.9	-1.3	-1.2	-1.2	-0.7	1.5	1.0	0.8
Na content in liver	6.0	6.8	9.1	-2.7	-3.0	-3.0	2.9	2.7	2.3	2.5	-2.4	-2.4	-2.0
Rb content in liver	0.5	0.6	1.7	1.1	0.4	0.4	-0.1	-1.1	-1.3	0.2	-0.7	-0.3	-0.8
Se content in liver	0.5	0.6	1.9	0.2	-0.5	-1.1	0.3	-0.2	-0.5	1.4	-0.8	-0.6	-1.1
Sr content in liver	0.6	0.5	1.5	0.9	0.2	0.2	-0.1	-0.9	-1.2	0.7	-0.7	-0.6	-0.9
Zn content in liver	0.4	0.5	1.7	1.0	0.4	0.2	-0.4	-1.1	-1.3	0.5	0.1	-0.1	-0.4
Bone: minimum diameter	0.2	0.4	0.8	-0.7	-0.8	-0.8	0.3	0.7	0.9	0.6	-0.1	0.1	0.4
Time in familiar zone, hab. session 1	0.7	0.8	1.5	0.4	0.8	0.8	-1.0	-0.4	-0.1	-1.0	1.0	1.2	1.2
Time in novel zone, hab. session 1	1.1	1.2	2.1	-1.3	-1.1	-1.0	1.4	1.3	1.2	0.4	-0.9	-1.1	-0.7
Total zone transitions, hab. session 1	0.3	0.4	1.1	-0.8	-0.4	-0.6	0.2	0.8	1.0	0.2	0.7	0.2	0.6
Total locomotion distance, hab. session 1	0.2	0.3	1.6	-0.2	0.1	-0.3	-0.3	0.2	0.4	0.1	1.3	0.5	0.7
Locomotion velocity, hab. session 1	0.2	0.2	1.5	-0.3	-0.1	-0.6	-0.1	0.2	0.3	0.6	1.2	0.1	0.3
Time in familiar zone, hab. session 2	0.3	0.3	1.0	0.5	0.7	1.0	-0.6	-0.4	-0.4	-0.8	0.3	0.5	0.4
Time in novel zone, hab. session 2	0.1	0.1	0.4	-0.2	-0.2	-0.6	0.1	0.2	0.3	0.3	0.2	0.0	0.1
Total zone transitions, hab. session 2	0.5	0.6	1.2	-0.7	-1.0	-1.1	0.8	0.7	0.6	1.1	-0.4	-0.5	-0.3
Total locomotion distance, hab. session 2	0.1	0.1	0.4	-0.4	-0.2	-0.5	0.1	0.3	0.5	0.3	0.6	0.2	0.3
Locomotion velocity, hab. session 2	0.2	0.3	0.6	-0.7	-0.5	-0.8	0.3	0.6	0.7	0.5	0.5	-0.1	0.2
Novel to familiar place preference ratio	0.3	0.4	0.9	0.6	0.5	0.4	-0.8	-0.6	-0.4	-0.2	0.6	0.9	0.8
Novelty place preference	0.2	0.3	0.6	0.6	0.4	0.3	-0.7	-0.6	-0.4	-0.0	0.4	0.8	0.6
Time in novel zone, NPP test	0.1	0.1	0.3	0.5	0.1	0.1	-0.5	-0.5	-0.3	0.2	0.1	0.5	0.4
Total zone transitions, NPP test	0.1	0.1	0.5	-0.1	-0.0	-0.6	-0.1	0.1	0.0	0.4	0.7	0.1	0.1
Total locomotion distance, NPP test	0.9	1.3	3.0	1.3	1.2	0.4	-1.3	-1.3	-1.4	-0.0	1.7	0.8	0.4
Locomotion velocity, NPP test	1.0	1.5	3.8	1.4	1.4	0.6	-1.4	-1.4	-1.4	-0.2	1.9	0.9	0.6
Intraocular pressure	0.9	1.5	4.9	1.9	1.0	0.7	-1.2	-1.7	-2.2	0.2	0.2	0.6	-0.2
Delta distance traveled before/after self-admin	0.5	0.5	1.5	-1.2	-0.7	-0.5	0.5	1.2	1.0	0.0	-0.2	-0.3	0.1
Delta ambulatory time before/after self-admin	0.2	0.4	1.0	-1.0	-0.6	-0.4	0.2	1.0	0.9	0.0	0.1	0.1	0.4
Parametrial fat weight	1.5	3.6	5.8	1.9	2.2	1.8	-2.4	-2.0	-1.8	-1.3	2.0	1.9	1.4
Pavlov. Cond. lever latency	0.7	0.9	1.7	1.1	1.2	1.3	-0.9	-1.2	-1.1	-0.8	0.6	0.6	0.4
Pavlov. Cond. magazine entry latency	0.5	0.7	1.2	-0.7	-1.0	-0.8	0.8	0.8	0.6	0.7	-1.1	-0.8	-0.9
Pavlov. Cond. change in total contacts	2.3	2.5	4.1	-1.9	-1.9	-1.8	1.5	2.0	2.0	1.3	-0.9	-1.0	-0.4
Pavlov. Cond. index score	2.3	2.9	4.4	-2.0	-2.0	-1.9	1.8	2.1	1.8	1.3	-1.2	-1.5	-1.2
Pavlov. Cond. latency score	1.7	2.1	3.2	-1.7	-1.7	-1.7	1.5	1.8	1.5	1.2	-1.1	-1.2	-1.0
Pavlov. Cond. lever contacts	1.0	1.2	1.8	-1.3	-1.3	-1.3	1.1	1.4	1.2	0.8	-0.8	-0.8	-0.6
Pavlov. Cond. magazine entry number	1.9	2.4	3.3	1.7	1.8	1.6	-1.7	-1.8	-1.5	-1.2	1.4	1.4	1.1
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.8	-0.0	-0.3	-0.8	0.3	0.0	-0.2	0.9	-0.1	-0.4	-0.5
Pavlov. Cond. lever-magazine prob. diff.	2.6	3.3	5.1	-2.1	-2.1	-2.0	1.9	2.3	2.0	1.3	-1.2	-1.6	-1.2
Pavlov. Cond. response bias	1.6	2.0	3.2	-1.7	-1.7	-1.4	1.5	1.8	1.6	0.9	-1.1	-1.2	-0.9
Pavlov. Cond. lever latency	1.9	2.6	4.7	0.8	1.8	1.6	-1.8	-0.9	-0.4	-2.2	1.9	1.9	1.8
Pavlov. Cond. magazine entry latency	1.1	1.5	2.5	-1.6	-1.4	-1.4	1.3	1.6	1.5	1.0	-0.5	-1.0	-0.8
Pavlov. Cond. change in total contacts	2.1	5.0	7.0	-1.9	-2.6	-2.3	2.6	1.9	1.5	2.4	-2.5	-2.4	-2.1
Pavlov. Cond. index score	2.2	3.4	4.5	-1.6	-2.1	-2.0	2.1	1.6	1.2	2.1	-1.9	-1.9	-1.8
Pavlov. Cond. latency score	2.2	3.6	4.7	-1.5	-2.2	-2.0	2.1	1.6	1.1	2.2	-2.0	-2.0	-1.9
Pavlov. Cond. lever contacts	1.7	2.4	4.6	-0.9	-1.7	-1.6	1.8	0.9	0.5	2.1	-1.7	-1.8	-1.7
Pavlov. Cond. magazine entry number	0.4	0.5	1.0	1.0	0.7	0.9	-0.7	-1.0	-1.0	-0.6	-0.0	0.3	0.2
Pavlov. Cond. intertrial magazine entries	3.3	7.2	13.3	3.6	3.0	2.2	-3.0	-3.6	-3.6	-1.3	1.9	1.9	1.0
Pavlov. Cond. lever-magazine prob. diff.	2.1	3.2	4.2	-1.7	-2.1	-1.9	2.0	1.7	1.4	1.9	-1.7	-1.8	-1.6
Pavlov. Cond. response bias	1.9	2.6	3.8	-1.4	-1.8	-1.9	1.9	1.4	1.1	2.0	-1.5	-1.7	-1.4
Time in closed arm before self-admin	0.9	1.6	2.6	-1.3	-1.3	-1.5	1.6	1.3	1.0	0.8	-0.9	-1.6	-1.2
Time in closed arm after self-admin	0.1	0.1	0.3	-0.2	-0.3	-0.4	-0.0	0.5	0.0	0.2	-0.3	-0.4	-0.5
Time in open arm before self-admin	0.5	0.6	1.2	1.1	0.7	0.7	-1.1	-0.9	-0.8	0.0	0.7	0.9	0.6
Time in open arm after self-admin	0.1	0.1	0.2	-0.1	-0.0	0.1	0.3	-0.3	-0.2	0.2	0.2	-0.5	-0.5
Bone: periosteal estimation	0.1	0.1	0.6	-0.3	-0.1	-0.2	-0.1	0.3	0.4	0.2	0.8	0.3	0.6
Bone: periosteal perimeter	0.0	0.1	0.2	0.0	-0.1	-0.2	-0.2	-0.0	0.0	0.4	0.4	0.2	0.3
Bone: post-yield work	2.8	4.9	12.8	-0.2	1.7	1.7	-1.7	0.2	1.2	-2.9	3.1	2.8	3.6
Progressive ratio test 1 active lever presses	1.1	1.9	3.1	0.9	1.5	1.5	-1.5	-0.9	-0.4	-1.7	1.7	1.5	1.8
Progressive ratio test 1 breakpoint	1.0	1.7	3.0	0.8	1.3	1.4	-1.3	-0.8	-0.2	-1.6	1.6	1.5	1.7
Progressive ratio test 1 inactive lever presses	0.3	0.8	2.0	1.1	1.0	0.7	-0.9	-1.1	-1.2	-0.5	1.4	0.1	-0.0
Progressive ratio test 2 active lever presses	0.5	0.7	1.4	1.1	0.8	0.8	-0.9	-1.2	-1.2	-0.4	-0.1	0.5	0.5
Progressive ratio test 2 breakpoint	0.4	0.5	1.1	1.0	0.6	0.6	-0.7	-1.0	-1.1	-0.2	-0.2	0.3	0.4
Progressive ratio test 2 inactive lever presses	0.5	1.7	3.6	1.9	1.3	1.5	-1.4	-1.7	-1.9	-0.7	0.4	0.6	0.2
Incentive Sensitization - Responses	0.4	1.0	2.8	0.5	-0.5	-0.5	0.2	-0.7	-1.2	1.4	-1.7	-1.0	-1.0
Incentive Sensitization - Breakpoint	0.4	1.0	2.7	0.6	-0.5	-0.5	0.2	-0.7	-1.3	1.4	-1.6	-1.0	-1.1
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.9	0.2	1.0	0.5	-0.3	-0.1	0.1	-0.9	0.6	0.4	0.4
Progressive ratio	0.6	1.7	3.4	-1.4	-1.3	-1.1	1.5	1.0	0.9	1.2	-1.3	-1.8	-1.2
Food seeking constrained by brief footshock	0.8	1.0	2.7	0.5	1.2	1.5	-0.9	-0.4	-0.1	-1.7	0.5	1.0	0.9
Seeking ratio, punishment vs. effort	0.6	1.4	3.0	0.9	1.2	1.3	-1.2	-0.5	-0.3	-1.6	0.8	1.7	1.4
Retroperitoneal fat weight	0.3	1.2	2.0	0.8	1.3	0.9	-1.3	-1.0	-0.9	-0.9	1.4	1.1	0.9
Reaction time number correct	0.1	0.4	1.3	0.9	0.5	0.5	-0.5	-0.9	-1.1	-0.1	0.0	0.1	-0.0
Reaction time mean minus median	0.2	1.4	1.9	-1.0	-1.3	-1.3	1.2	0.8	0.6	1.3	-1.4	-1.3	-1.3
Reaction time mean minus median AUC	0.1	0.8	1.9	-0.6	-0.9	-0.9	0.8	0.3	0.1	1.1	-0.9	-1.4	-1.3
Reaction time num false alarms	0.7	1.3	2.6	-0.9	-0.8	-1.4	1.4	0.9	0.6	1.3	-0.1	-1.6	-1.3
Reaction time num false alarms AUC	0.5	1.2	2.2	-1.0	-0.9	-1.4	1.4	0.9	0.7	1.2	-0.3	-1.5	-1.1
Reaction time trials correct on left	0.1	0.4	1.3	0.9	0.5	0.5	-0.5	-0.9	-1.1	-0.1	0.0	0.1	-0.0
Reaction time trials on left	0.1	0.5	1.6	1.0	0.6	0.6	-0.6	-1.0	-1.3	-0.2	0.0	0.2	-0.0
Reaction time mean	0.2	0.5	1.5	0.3	-0.6	-0.3	0.6	-0.2	-0.4	0.8	-1.2	-0.9	-1.1
Reaction time mean AUC	0.4	0.9	2.0	0.0	-0.9	-0.6	0.9	-0.0	-0.3	1.1	-1.4	-1.3	-1.4
Median of all reaction times	0.2	0.4	1.2	0.6	-0.3	0.1	0.3	-0.4	-0.6	0.5	-1.1	-0.6	-0.9
Reaction time omissions	1.0	1.6	5.2	1.8	1.2	1.0	-1.2	-1.9	-2.3	-0.1	0.4	0.2	-0.4
Reaction time false alarm rate	0.9	1.2	1.8	-1.3	-0.9	-1.3	1.3	1.3	1.2	0.8	-0.1	-1.2	-0.8
Reaction time premature initiation rate	0.3	0.5	1.4	-0.9	-0.8	-0.4	0.5	0.8	1.2	-0.0	-1.0	0.2	0.2
Reaction time premature initiations	0.0	0.1	0.6	-0.2	-0.3	0.1	0.0	0.1	0.4	-0.2	-0.8	0.4	0.3
Std. dev. reaction times	0.1	0.3	1.0	-0.1	-0.6	-0.3	0.4	0.0	-0.1	0.6	-1.0	-0.6	-0.7
Reaction time trials completed	0.1	0.5	1.6	1.0	0.6	0.6	-0.6	-1.0	-1.3	-0.2	0.0	0.2	-0.0
Reaction time trials AUC	0.2	0.6	1.9	1.1	0.7	0.7	-0.6	-1.1	-1.4	-0.1	-0.0	0.2	-0.0
Run reversals in cocaine runway, females	0.7	0.8	1.4	0.9	1.1	1.2	-0.8	-0.1	-0.0	-1.0	1.0	1.1	0.8
Run reversals in cocaine runway, males	2.0	2.2	4.4	-2.0	-1.8	-1.2	1.7	1.9	2.1	0.7	-1.0	-1.0	-0.2
Latency to leave start box in cocaine runway	0.9	1.2	3.1	1.4	0.6	1.2	-1.3	-1.8	-1.7	-0.2	-0.2	0.9	0.4
Latency to leave start box in cocaine runway, F	0.2	0.3	0.8	0.2	-0.4	0.2	-0.3	-0.9	-0.9	0.4	-0.9	-0.0	-0.2
Latency to leave start box in cocaine runway, M	1.0	1.0	2.6	1.6	0.9	1.0	-0.9	-1.4	-1.6	-0.1	0.2	0.6	0.1
Std. dev. time between licks in bursts	0.5	1.0	3.1	1.5	0.6	-0.1	-0.8	-1.5	-1.7	1.0	0.1	0.1	-0.7
Total sessions with >9 infusions	0.6	0.8	1.1	0.9	1.0	1.0	-1.0	-1.0	-1.0	-0.6	1.0	0.3	0.3
Short access day 1 total inactive lever presses	0.2	0.3	1.0	0.2	0.0	0.9	-0.7	-0.5	-0.3	-0.8	0.3	0.4	1.0
Short access day 10 total inactive lever presses	0.0	0.3	0.7	0.6	0.5	0.6	-0.8	-0.7	-0.7	-0.4	0.4	0.4	0.4
Short access day 1 total infusions	1.6	3.2	5.1	1.8	1.7	2.2	-2.3	-2.0	-1.8	-1.5	1.4	1.6	1.5
Short access day 10 total infusions	0.2	0.3	0.8	0.2	0.3	0.6	-0.7	-0.2	0.1	-0.3	0.7	0.6	0.9
Short access total infusions	0.7	1.0	1.7	1.0	0.9	1.1	-1.3	-1.1	-0.8	-0.7	0.7	1.0	1.1
Short access day 1 locomotion	0.1	0.2	0.6	-0.1	-0.3	-0.4	0.2	-0.1	-0.3	0.6	0.0	-0.8	-0.4
Short access day 10 total locomotion	0.1	0.4	1.1	-0.5	-0.6	-0.9	0.7	0.1	-0.1	0.5	-0.5	-1.1	-0.9
Short access total locomotion	0.3	0.4	1.1	-0.5	-0.7	-0.9	0.6	0.3	0.0	0.7	-0.3	-1.1	-0.8
One hour access (0.3 mA shock)	1.6	1.9	4.3	0.8	1.5	1.0	-1.5	-0.8	-0.6	-1.4	2.1	1.6	1.8
Compulsive drug intake	0.4	0.6	4.7	-0.0	0.7	-0.1	-0.3	0.0	-0.0	-0.4	2.2	0.2	0.1
One hour access (shock baseline)	0.6	1.5	2.2	1.3	1.2	1.3	-1.5	-1.3	-1.0	-1.1	0.5	1.4	1.4
Social response proportion	1.6	2.0	3.9	1.7	1.4	1.6	-1.6	-1.9	-2.0	-1.2	-0.0	1.2	0.6
Social responses	2.3	3.0	5.9	2.3	1.7	1.3	-2.1	-2.4	-2.4	-0.8	0.3	1.7	0.8
Social time	0.8	1.2	3.0	0.5	-0.5	-0.9	0.7	-0.6	-1.0	1.6	-1.0	-1.5	-1.7
Soleus weight	0.2	0.5	1.5	-1.2	-0.4	-0.5	0.6	1.1	1.2	-0.5	0.4	0.0	0.6
Bone: stiffness	0.6	1.0	2.4	-1.5	-1.0	-0.9	1.0	1.5	1.6	0.4	-0.2	-0.7	-0.1
Tibialis anterior weight	5.1	17.4	28.7	-5.4	-4.7	-4.1	4.9	5.2	5.0	2.7	-2.3	-3.8	-2.1
Time to tail flick, vehicle, before self-admin	0.5	0.7	2.1	-1.0	-0.6	-0.5	0.8	1.4	1.4	-0.1	0.4	-0.4	-0.2
Time to tail flick, vehicle, after self-admin	0.3	0.7	2.1	-0.8	-0.7	-0.1	0.8	1.5	1.3	-0.2	-1.1	-0.3	-0.2
Time to tail flick, test, before self-admin	0.3	0.3	2.5	0.1	0.3	-0.2	0.0	0.2	-0.1	0.1	1.6	-0.4	-0.3
Time to tail flick, test, after self-admin	3.8	4.0	6.4	2.4	2.2	2.4	-2.3	-2.3	-2.5	-1.4	1.3	1.5	0.7
Delta time to tail flick, vehicle, before/after SA	0.5	0.5	1.5	1.0	0.6	1.2	-0.5	-0.6	-0.7	-0.6	-0.8	0.6	0.3
Delta time to tail flick, test, before/after SA	2.6	3.2	5.3	2.2	1.9	2.3	-1.9	-2.2	-2.0	-1.5	0.1	1.6	0.8
Tibia length	2.0	5.6	11.5	-1.2	-2.3	-2.4	2.2	1.2	0.4	3.4	-1.9	-3.3	-3.4
Ambulatory time before self-admin	0.0	0.1	0.5	0.3	-0.4	-0.3	0.2	-0.2	-0.1	0.6	-0.7	-0.1	-0.0
Ambulatory time after self-admin	0.8	1.3	2.5	-1.2	-1.6	-1.3	1.2	1.3	1.2	1.1	-0.9	-0.7	-0.2
Bone: tissue strength	0.1	0.2	0.4	0.6	0.2	-0.1	0.0	-0.6	-0.6	0.5	0.3	-0.3	-0.2
Total heroin consumption	0.7	0.8	1.6	-1.3	-0.9	-1.0	0.9	1.1	1.1	0.4	-1.1	-0.7	-0.1
Bone: trabecular number	0.6	1.1	2.8	1.5	1.1	0.9	-1.0	-1.5	-1.7	-0.0	0.8	0.2	-0.3
Bone: trabecular spacing	1.3	1.8	5.3	-2.1	-1.2	-1.1	1.2	2.1	2.3	-0.0	-0.3	-0.3	0.4
Bone: trabecular thickness	0.2	0.2	0.5	-0.6	-0.3	-0.5	0.3	0.6	0.6	0.3	0.7	-0.4	-0.1
Bone: trabecular tissue density	2.0	3.6	5.8	-2.4	-2.1	-1.8	2.0	2.4	2.3	0.9	-1.6	-1.6	-1.0
Water consumed over 24 hours	0.4	0.8	1.3	-1.0	-1.1	-0.9	1.1	1.0	0.9	0.9	-0.7	-0.9	-0.6
Number of responses in last shaping day	0.5	0.7	2.1	-1.4	-1.0	-0.7	0.5	1.0	1.1	0.3	-0.6	-0.6	0.1