Hub : Genes

Nudt18

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Nudt18 0.31 0.17 2.8e-08 0.13 0.11 0.1 0.12 2.5e-07 1.2e-06 6.9e-06 7.2e-07
2 IC gene expression Nudt18 0.25 0.14 1.3e-09 0.19 0.23 0.23 0.23 2.9e-08 6.4e-10 5.6e-10 3.3e-10
3 Brain gene expression Nudt18 0.11 0.07 7.4e-07 0.04 0.06 0.05 0.05 2.5e-04 5.2e-06 8.8e-06 1.7e-05
4 pVTA gene expression Nudt18 0.12 0.09 1.9e-06 0.04 0.06 0.07 0.06 3.1e-04 5.9e-06 5.0e-06 1.7e-05
5 Adipose gene expression Nudt18 0.02 0.02 4.1e-03 0.01 0.01 0.01 0.01 2.5e-02 7.3e-03 1.2e-02 1.9e-02
6 NAcc gene expression Nudt18 0.2 0.11 0.0e+00 0.14 0.16 0.16 0.16 4.2e-21 7.5e-24 9.5e-24 5.9e-24
7 PL gene expression Nudt18 0.14 0.09 8.5e-13 0.12 0.11 0.11 0.11 1.1e-12 6.6e-12 1.1e-11 8.2e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density1.12.02.2-1.31.41.5-1.31.51.4-1.4
Area under the delay curve0.00.10.3-0.3-0.0-0.0-0.5-0.1-0.20.3
BMI with tail0.82.83.81.9-1.9-1.81.9-1.6-1.21.2
BMI without tail0.10.82.11.4-1.2-0.81.1-0.40.0-0.1
Body weight0.62.73.11.3-1.6-1.61.6-1.7-1.71.8
Weight adjusted by age0.51.52.40.9-1.0-1.21.1-1.4-1.51.5
Bone surface0.91.72.3-1.51.51.4-1.51.21.0-1.0
Bone volume0.91.72.1-1.41.41.4-1.41.31.1-1.1
Breakpoint value in progressive ratio session0.00.00.1-0.1-0.1-0.20.1-0.2-0.20.3
Number of licking bursts0.00.00.10.3-0.3-0.10.2-0.10.0-0.0
Context. condit. distance diff. score0.91.03.01.7-1.0-0.41.00.31.0-1.1
Locomotion velocity, session 10.10.10.20.0-0.1-0.30.3-0.3-0.40.4
Locomotion distance, session 10.60.82.1-1.41.20.9-0.70.60.2-0.2
Locomotion velocity, session 20.30.30.8-0.90.90.6-0.50.40.2-0.2
Locomotion distance, session 21.31.85.3-2.31.91.3-1.10.80.2-0.1
Locomotion velocity, session 31.41.73.01.7-1.5-1.31.5-1.1-0.70.7
Locomotion distance, session 30.20.20.80.9-0.6-0.40.5-0.10.2-0.2
Stereotopy head waving bouts, day 30.50.60.80.5-0.6-0.80.8-0.8-0.90.9
Stereotopy head waving duration, day 31.72.12.90.9-1.2-1.41.3-1.6-1.71.7
Locomotion velocity, session 71.61.74.51.0-0.10.60.01.32.1-2.1
Locomotion distance, session 71.21.64.10.60.20.8-0.11.42.0-2.0
Stereotopy head waving bouts, day 70.80.91.90.2-0.6-0.90.6-1.1-1.41.4
Stereotopy head waving duration, day 71.31.72.70.7-1.1-1.30.8-1.5-1.61.6
Locomotion velocity, session 80.10.20.50.6-0.4-0.40.7-0.20.1-0.0
Locomotion distance, session 80.40.61.0-0.60.80.8-0.20.91.0-1.0
Degree of sensitization distance2.12.34.5-0.51.01.4-0.91.82.1-2.1
Degree of sensitization stereotypy0.70.81.30.5-0.7-0.90.7-1.0-1.11.1
Conditioned locomotion0.10.10.30.6-0.5-0.30.2-0.10.2-0.2
Cocaine response after cond. corrected1.21.73.61.9-1.7-1.41.5-1.0-0.50.5
Cocaine response after cond. not corrected0.60.91.71.3-1.1-1.01.1-0.7-0.40.4
Cocaine response before conditioning1.01.22.6-1.61.51.2-1.10.80.4-0.4
Saline control response0.60.81.6-1.31.10.9-1.00.70.4-0.4
Bone: connectivity density1.93.03.7-1.41.61.8-1.51.91.9-1.9
Bone: cortical apparent density0.40.62.01.4-1.1-0.60.8-0.20.3-0.3
Bone: cortical area0.20.20.7-0.90.70.4-0.50.30.00.0
Bone: cortical porosity0.50.51.3-0.4-0.0-0.40.2-0.8-1.11.1
Bone: cortical porosity0.30.30.7-0.70.3-0.1-0.2-0.4-0.80.9
Bone: cortical thickness0.00.00.2-0.40.30.2-0.20.10.1-0.0
Bone: cortical thickness0.30.30.80.8-0.7-0.50.9-0.30.0-0.0
Bone: cortical tissue density0.40.72.21.5-1.1-0.70.9-0.20.4-0.3
Condit. Reinf. active minus inactive responses0.20.20.5-0.3-0.0-0.30.2-0.5-0.70.7
Condit. Reinf. active-inactive response ratio2.12.22.51.2-1.4-1.61.6-1.6-1.51.5
Condit. Reinf. active responses0.40.51.5-1.20.90.7-0.80.40.00.0
Condit. Reinf. inactive responses4.45.77.7-2.82.72.6-2.72.21.7-1.7
Incentive salience index mean0.30.40.9-0.70.3-0.10.0-0.5-0.90.9
Condit. Reinf. lever presses0.30.41.6-1.20.80.3-0.4-0.1-0.60.6
Condit. Reinf. active minus inactive responses0.30.40.4-0.50.60.6-0.60.70.7-0.7
Condit. Reinf. active-inactive response ratio0.10.20.30.5-0.5-0.50.5-0.4-0.20.2
Condit. Reinf. active responses0.81.21.3-1.01.11.1-1.01.11.1-1.1
Condit. Reinf. inactive responses1.82.73.2-1.61.71.8-1.61.71.6-1.6
Condit. Reinf. lever presses0.71.12.4-1.61.31.1-1.20.80.4-0.4
Condit. Reinf. lever reinforcers received0.71.01.1-0.91.01.0-0.91.01.0-1.0
Conditioned reinforcement - actives0.20.91.7-0.30.70.9-0.71.11.3-1.3
Conditioned reinforcement - inactives2.05.66.7-2.32.52.6-2.42.42.2-2.1
Conditioned locomotion0.10.10.2-0.10.30.3-0.00.30.4-0.4
Patch foraging indifference point 0 sec2.87.812.0-3.53.23.0-3.32.51.7-1.7
Patch foraging indifference point AUC0.30.81.51.2-1.1-1.00.8-0.8-0.50.5
Delay disc. indifference point, 0s delay1.41.53.1-1.61.31.2-1.81.00.7-0.7
Delay disc. indifference point, 16s delay0.20.30.6-0.50.40.5-0.80.50.5-0.4
Delay disc. indifference point, 2s delay0.60.71.60.0-0.5-0.70.1-1.0-1.31.3
Delay disc. indifference point, 24s delay0.20.40.60.7-0.8-0.70.6-0.6-0.40.5
Delay disc. indifference point, 4s delay1.41.41.80.9-1.3-1.30.7-1.4-1.31.3
Delay disc. indifference point, 8s delay0.10.20.5-0.50.30.4-0.70.30.2-0.2
Indifference point function ln k0.10.41.3-1.10.80.6-0.50.40.0-0.0
Indifference point function log k0.10.41.3-1.10.80.6-0.50.40.0-0.0
Patch foraging total patch changes 0 sec2.26.510.5-3.23.02.7-3.12.21.5-1.4
Patch foraging total patch changes 12 sec1.92.54.8-2.01.71.6-2.21.30.9-0.9
Patch foraging total patch changes 18 sec1.02.42.8-1.41.61.7-1.71.61.4-1.4
Patch foraging total patch changes 24 sec0.20.81.7-1.31.10.8-1.30.5-0.00.0
Patch foraging total patch changes 6 sec0.30.51.1-0.60.70.8-1.10.70.6-0.6
Patch foraging time to switch 0 sec0.20.71.1-0.50.70.9-0.71.01.1-1.0
Patch foraging water rate 0 sec0.10.20.6-0.2-0.0-0.30.3-0.5-0.80.8
Patch foraging water rate 12 sec0.10.51.00.1-0.3-0.60.5-0.8-1.01.0
Patch foraging water rate 18 sec1.94.34.81.9-2.1-2.22.1-2.2-2.12.1
Patch foraging water rate 24 sec0.60.81.61.3-1.0-0.91.1-0.7-0.50.5
Patch foraging water rate 6 sec0.81.22.9-0.1-0.4-0.90.5-1.3-1.71.7
Seeking ratio, delayed vs. immediate footshock0.91.31.7-1.01.31.2-1.11.21.0-1.0
Distance traveled before self-admin0.20.41.0-0.70.2-0.2-0.2-0.6-0.91.0
Distance traveled after self-admin1.73.03.51.5-1.7-1.91.7-1.9-1.71.8
Extensor digitorum longus weight10.441.551.04.8-6.0-6.85.9-7.1-7.17.1
Bone: elastic displacement1.01.22.1-1.51.41.2-1.11.00.7-0.7
Bone: elastic work1.52.04.6-2.11.91.5-1.51.10.5-0.5
Bone: endosteal estimation0.00.10.2-0.40.30.1-0.2-0.1-0.40.4
Bone: endosteal perimeter0.10.30.8-0.90.60.4-0.60.1-0.30.3
Epididymis fat weight0.41.92.6-1.01.41.5-0.71.61.6-1.6
Delta time in closed arm before/after self-admin5.14.85.7-2.12.32.4-2.32.22.0-2.0
Delta time in open arm before/after self-admin0.10.10.20.3-0.4-0.40.4-0.3-0.20.3
Diff in mean of infusions in LGA sessions0.40.71.10.5-0.7-0.90.8-1.0-0.91.1
Delay discount exponential model param0.10.20.4-0.00.40.40.20.50.6-0.6
Extinction: sum of active levers before priming1.52.22.5-1.31.51.6-1.41.61.6-1.5
Active lever presses in extinction session 60.30.30.7-0.00.30.5-0.40.70.9-0.8
Bone: final force0.00.10.2-0.20.1-0.20.1-0.3-0.40.4
Bone: final moment0.10.10.4-0.60.40.1-0.2-0.1-0.30.4
Food consumed during 24 hour testing period0.51.02.0-1.41.31.1-1.00.90.6-0.6
Glucose0.20.31.01.0-0.8-0.50.5-0.30.0-0.0
Heart weight0.61.01.4-1.11.01.0-1.20.90.8-0.8
Delay discount hyperbolic model param0.20.20.5-0.00.40.40.20.60.7-0.7
Intermittent access intake day 1-15 change0.52.83.6-1.31.51.7-1.61.81.9-1.9
Intermittent access intake escalation0.63.43.9-1.61.71.9-1.92.01.9-1.9
Intermittent access intake escalation 20.61.11.7-0.70.81.0-0.91.21.3-1.3
Intermitt. access day 1 inactive lever presses0.00.00.10.2-0.2-0.1-0.00.00.1-0.1
Intermitt. access day 15 inactive lever presses0.00.10.2-0.30.30.4-0.50.30.2-0.2
Intermitt. access escalation Index0.00.00.1-0.30.10.0-0.2-0.1-0.20.2
Intermittent access day 1 total infusions0.00.00.0-0.00.10.0-0.00.0-0.10.0
Intermittent access day 15 total infusions1.12.63.0-1.41.61.7-1.61.71.6-1.6
Intermittent access terminal intake (last 3 days)0.50.91.4-0.50.81.0-0.81.11.2-1.2
Intermittent access total infusions0.81.01.4-0.60.91.0-0.71.11.2-1.2
Intermittent access day 1 locomotion0.10.20.5-0.70.60.5-0.60.30.1-0.1
Intermittent access day 15 total locomotion0.10.20.4-0.20.40.5-0.20.60.7-0.6
Intermittent access total locomotion0.10.10.2-0.30.40.4-0.30.40.4-0.3
Intermittent access standard deviation0.10.40.6-0.60.60.7-0.70.70.6-0.5
Left kidney weight0.00.10.2-0.30.20.1-0.1-0.2-0.50.5
Right kidney weight0.10.71.6-1.31.00.7-1.20.3-0.30.3
Cocaine induced anxiety0.41.02.5-1.61.20.9-1.30.5-0.00.0
Post-drug Anxiety2.52.84.6-2.12.01.8-2.01.51.0-1.0
Baseline Anxiety0.10.20.50.20.00.2-0.00.50.7-0.7
Tail length0.63.13.8-1.91.91.9-1.91.71.4-1.4
Length with tail0.10.30.9-1.00.50.4-0.7-0.0-0.50.5
Length without tail0.94.57.61.1-1.7-2.11.5-2.4-2.72.7
Times rat made contact with spout0.30.30.6-0.20.40.6-0.30.70.8-0.8
Lifetime Intake0.40.50.9-0.40.70.7-0.50.80.9-0.9
Liver weight, left0.81.33.0-0.1-0.5-0.90.8-1.3-1.71.7
Liver weight, right0.61.01.60.8-1.0-1.01.3-1.0-0.90.9
Locomotor activity1.01.53.4-1.90.90.2-0.8-0.7-1.61.6
Locomotor testing distance1.63.910.0-3.22.51.9-2.51.20.2-0.2
Locomotor testing rearing1.65.913.8-3.73.12.5-3.01.60.5-0.5
Locomotion in novel chamber0.60.81.1-0.90.91.0-1.10.90.8-0.8
Locomotion in novel chamber post-restriction0.41.11.31.0-1.0-1.11.0-1.1-1.11.1
Fecal boli incidents, locomotor time 10.30.71.50.3-0.6-0.80.5-1.0-1.21.2
Change in fecal boli incidents, locomotor task0.50.60.91.0-0.8-0.80.9-0.7-0.50.5
Time >=10cm from walls, locomotor time 11.01.21.7-1.11.31.2-0.91.21.1-1.0
Bouts of movement, locomotor time 14.05.26.22.1-2.4-2.52.2-2.4-2.22.1
Total resting periods, locomotor time 15.15.96.92.4-2.6-2.62.5-2.5-2.22.1
Rest time, locomotor task time 11.72.83.31.7-1.8-1.81.8-1.7-1.51.4
Distance moved, locomotor task time 11.02.93.6-1.41.71.8-1.41.91.8-1.7
Vertical activity count, locomotor time 10.42.43.6-1.91.81.7-1.71.41.0-1.0
Time >=10cm from walls, locomotor time 20.20.50.60.6-0.6-0.70.8-0.7-0.70.6
Bouts of movement, locomotor time 21.65.37.22.2-2.7-2.51.7-2.4-2.22.2
Total resting periods, locomotor time 21.55.98.02.3-2.8-2.71.9-2.6-2.32.3
Rest time, locomotor task time 21.42.33.51.8-1.9-1.71.4-1.5-1.11.0
Distance moved, locomotor task time 23.64.86.4-2.32.52.4-2.12.21.9-1.8
Vertical activity count, locomotor time 20.71.72.9-1.71.71.4-1.41.10.7-0.7
Light reinforcement 10.62.94.9-0.91.31.7-1.12.02.2-2.2
Light reinforcement 20.30.61.21.1-0.4-0.00.60.51.1-1.1
Bone: marrow area0.00.10.2-0.50.40.2-0.3-0.0-0.20.2
Bone: maximum diameter0.20.40.70.4-0.5-0.70.5-0.7-0.80.8
Bone: maximum force0.10.20.5-0.50.3-0.1-0.0-0.4-0.70.7
Bone: maximum moment0.20.31.0-1.00.70.2-0.4-0.1-0.50.6
Mean time between licks in bursts0.52.93.3-1.71.81.8-1.41.81.6-1.6
Mean num. licks in bursts0.10.30.3-0.40.50.5-0.40.60.6-0.6
Cd content in liver0.50.51.2-0.1-0.3-0.60.2-0.8-1.11.1
Co content in liver5.56.47.52.6-2.7-2.72.3-2.6-2.42.4
Cu content in liver0.40.50.60.7-0.8-0.80.6-0.7-0.60.6
Fe content in liver1.51.92.1-1.21.31.4-1.41.41.4-1.4
K content in liver0.70.71.2-0.40.50.8-0.80.91.1-1.1
Mg content in liver1.81.92.8-0.91.21.4-1.21.61.7-1.7
Mn content in liver2.52.83.1-1.51.71.8-1.71.81.7-1.7
Na content in liver0.60.61.5-1.20.50.1-0.8-0.4-1.01.0
Rb content in liver0.10.10.50.7-0.5-0.30.3-0.10.2-0.2
Se content in liver3.84.48.6-2.92.62.2-2.41.71.1-1.1
Sr content in liver0.20.20.4-0.50.50.4-0.60.30.2-0.2
Zn content in liver0.70.81.7-1.31.10.9-1.10.70.4-0.4
Bone: minimum diameter0.20.30.9-1.00.70.2-0.5-0.1-0.50.5
Time in familiar zone, hab. session 10.10.10.20.5-0.4-0.40.5-0.3-0.20.2
Time in novel zone, hab. session 11.51.62.31.5-1.5-1.31.1-1.3-1.11.1
Total zone transitions, hab. session 10.10.10.3-0.60.30.1-0.1-0.2-0.40.5
Total locomotion distance, hab. session 10.50.71.7-1.31.10.8-0.90.50.1-0.1
Locomotion velocity, hab. session 11.31.84.4-2.11.81.4-1.51.00.4-0.4
Time in familiar zone, hab. session 23.64.15.62.4-2.3-2.22.3-1.9-1.41.5
Time in novel zone, hab. session 21.41.52.2-1.51.41.3-1.51.10.8-0.9
Total zone transitions, hab. session 20.50.71.7-0.50.0-0.40.4-0.8-1.31.3
Total locomotion distance, hab. session 20.10.20.4-0.70.40.1-0.1-0.2-0.50.5
Locomotion velocity, hab. session 20.20.30.7-0.70.30.0-0.1-0.4-0.80.8
Novel to familiar place preference ratio1.62.12.5-1.51.61.6-1.51.51.2-1.3
Novelty place preference1.31.72.0-1.31.41.4-1.31.31.1-1.1
Time in novel zone, NPP test0.81.01.2-1.01.11.1-1.01.00.8-0.8
Total zone transitions, NPP test0.81.22.6-1.61.51.2-1.00.90.5-0.5
Total locomotion distance, NPP test4.25.97.9-2.82.82.7-2.32.41.9-1.9
Locomotion velocity, NPP test4.05.77.7-2.82.82.6-2.32.31.9-1.9
Intraocular pressure0.50.81.0-1.01.01.0-0.50.90.8-0.8
Delta distance traveled before/after self-admin5.45.98.22.9-2.8-2.62.6-2.3-1.81.8
Delta ambulatory time before/after self-admin3.35.77.42.7-2.7-2.62.5-2.3-1.91.8
Parametrial fat weight1.53.54.2-1.41.82.0-1.82.02.0-2.0
Pavlov. Cond. lever latency0.20.20.70.8-0.7-0.50.4-0.3-0.0-0.0
Pavlov. Cond. magazine entry latency0.00.00.0-0.10.20.2-0.20.20.2-0.2
Pavlov. Cond. change in total contacts0.50.51.2-0.1-0.2-0.50.6-0.8-1.01.1
Pavlov. Cond. index score0.10.10.2-0.40.30.1-0.0-0.1-0.20.3
Pavlov. Cond. latency score0.10.10.3-0.60.50.3-0.20.1-0.10.2
Pavlov. Cond. lever contacts0.20.20.7-0.80.70.5-0.40.30.1-0.1
Pavlov. Cond. magazine entry number0.20.30.5-0.30.40.5-0.60.60.6-0.7
Pavlov. Cond. intertrial magazine entries0.80.91.9-1.41.21.0-1.20.70.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.30.1-0.10.2-0.3-0.40.5
Pavlov. Cond. response bias0.10.10.20.0-0.1-0.20.3-0.3-0.40.4
Pavlov. Cond. lever latency0.30.41.11.0-0.6-0.20.40.20.7-0.7
Pavlov. Cond. magazine entry latency0.50.71.4-1.21.00.9-1.00.60.3-0.3
Pavlov. Cond. change in total contacts0.30.81.9-0.1-0.3-0.70.4-1.0-1.41.4
Pavlov. Cond. index score0.20.30.9-1.00.50.2-0.4-0.2-0.70.7
Pavlov. Cond. latency score0.20.41.2-1.10.70.3-0.6-0.1-0.60.6
Pavlov. Cond. lever contacts0.30.51.5-1.20.80.4-0.60.0-0.50.5
Pavlov. Cond. magazine entry number0.30.30.70.8-0.7-0.60.7-0.4-0.20.2
Pavlov. Cond. intertrial magazine entries3.06.57.9-2.02.52.7-2.22.82.8-2.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.70.30.0-0.3-0.4-0.80.8
Pavlov. Cond. response bias0.30.51.6-1.20.80.4-0.6-0.0-0.50.5
Time in closed arm before self-admin1.52.63.21.5-1.7-1.81.7-1.7-1.51.5
Time in closed arm after self-admin0.00.00.10.2-0.2-0.20.2-0.2-0.20.2
Time in open arm before self-admin0.10.10.2-0.30.30.3-0.40.20.1-0.1
Time in open arm after self-admin0.20.20.3-0.50.40.4-0.60.40.2-0.2
Bone: periosteal estimation0.10.10.4-0.70.50.2-0.4-0.0-0.30.3
Bone: periosteal perimeter0.10.10.3-0.50.30.2-0.4-0.0-0.20.2
Bone: post-yield work0.10.10.20.4-0.10.00.30.20.4-0.4
Progressive ratio test 1 active lever presses0.40.71.41.2-1.0-0.91.1-0.6-0.30.3
Progressive ratio test 1 breakpoint0.50.81.51.2-1.1-1.01.2-0.7-0.40.4
Progressive ratio test 1 inactive lever presses0.20.61.2-0.20.50.7-0.50.91.1-1.1
Progressive ratio test 2 active lever presses0.10.10.40.6-0.4-0.20.4-0.00.2-0.2
Progressive ratio test 2 breakpoint0.00.10.20.4-0.3-0.10.30.00.1-0.1
Progressive ratio test 2 inactive lever presses0.10.30.4-0.20.40.5-0.40.60.7-0.6
Incentive Sensitization - Responses0.10.30.4-0.40.50.6-0.50.60.6-0.6
Incentive Sensitization - Breakpoint0.20.50.6-0.50.60.8-0.70.70.7-0.7
Sum of active levers in priming session hrs 5-60.10.10.40.6-0.3-0.00.20.10.4-0.3
Progressive ratio0.00.10.40.7-0.4-0.20.4-0.2-0.10.1
Food seeking constrained by brief footshock6.07.512.63.5-3.2-2.93.2-2.4-1.61.6
Seeking ratio, punishment vs. effort0.91.92.51.5-1.6-1.61.5-1.4-1.01.0
Retroperitoneal fat weight0.00.20.40.30.10.3-0.30.50.6-0.6
Reaction time number correct0.41.62.21.3-1.4-1.31.5-1.2-1.01.0
Reaction time mean minus median0.00.10.2-0.40.20.1-0.3-0.1-0.40.4
Reaction time mean minus median AUC0.00.00.1-0.10.0-0.0-0.0-0.1-0.30.3
Reaction time num false alarms0.10.10.20.1-0.1-0.10.4-0.3-0.40.4
Reaction time num false alarms AUC0.00.10.20.1-0.1-0.10.4-0.2-0.40.4
Reaction time trials correct on left0.41.62.21.3-1.4-1.31.5-1.2-1.01.0
Reaction time trials on left0.41.31.91.2-1.3-1.21.4-1.1-0.90.8
Reaction time mean0.00.10.20.0-0.0-0.20.3-0.3-0.40.4
Reaction time mean AUC0.10.20.40.1-0.1-0.30.3-0.5-0.60.6
Median of all reaction times0.10.10.20.2-0.2-0.30.5-0.3-0.40.4
Reaction time omissions1.11.92.5-0.91.31.5-1.11.61.6-1.6
Reaction time false alarm rate0.10.10.2-0.40.50.5-0.20.40.2-0.2
Reaction time premature initiation rate2.53.94.82.1-2.2-2.12.2-1.9-1.61.6
Reaction time premature initiations2.06.17.72.7-2.8-2.62.8-2.4-1.92.0
Std. dev. reaction times0.00.10.2-0.20.1-0.00.1-0.2-0.40.4
Reaction time trials completed0.41.31.91.2-1.3-1.21.4-1.1-0.90.8
Reaction time trials AUC0.31.11.61.1-1.2-1.11.3-1.0-0.80.8
Run reversals in cocaine runway, females2.62.93.5-1.41.61.9-1.61.91.8-1.7
Run reversals in cocaine runway, males1.31.42.00.6-0.9-1.31.2-1.4-1.41.4
Latency to leave start box in cocaine runway0.40.50.60.6-0.7-0.70.6-0.7-0.80.8
Latency to leave start box in cocaine runway, F1.01.31.80.8-1.1-1.10.9-1.2-1.31.3
Latency to leave start box in cocaine runway, M0.10.10.1-0.10.20.3-0.30.30.3-0.3
Std. dev. time between licks in bursts2.34.37.8-2.82.62.3-2.01.91.3-1.3
Total sessions with >9 infusions0.10.10.20.2-0.2-0.30.5-0.3-0.20.2
Short access day 1 total inactive lever presses0.20.50.8-0.80.80.7-0.90.60.4-0.4
Short access day 10 total inactive lever presses0.00.10.2-0.10.20.4-0.40.40.4-0.5
Short access day 1 total infusions0.20.30.60.7-0.6-0.60.8-0.4-0.30.3
Short access day 10 total infusions0.10.20.4-0.20.1-0.20.2-0.4-0.60.6
Short access total infusions0.00.00.1-0.00.0-0.10.2-0.2-0.20.2
Short access day 1 locomotion0.30.41.10.0-0.2-0.50.4-0.8-1.01.0
Short access day 10 total locomotion0.00.10.5-0.50.30.3-0.70.20.0-0.1
Short access total locomotion0.10.20.5-0.70.50.2-0.4-0.0-0.30.4
One hour access (0.3 mA shock)1.01.21.8-1.11.11.2-1.31.10.9-0.9
Compulsive drug intake1.01.52.2-1.41.41.3-1.51.10.8-0.9
One hour access (shock baseline)0.00.00.0-0.20.10.1-0.20.10.00.0
Social response proportion1.11.42.61.6-1.4-1.31.5-0.9-0.30.4
Social responses0.70.91.4-0.60.70.8-0.91.01.2-1.2
Social time0.91.42.6-1.61.41.3-1.41.00.7-0.6
Soleus weight1.44.25.31.9-2.0-2.12.3-2.1-1.91.9
Bone: stiffness0.40.71.20.4-0.6-0.80.6-0.9-1.01.1
Tibialis anterior weight6.020.727.93.1-4.0-4.73.9-5.1-5.35.3
Time to tail flick, vehicle, before self-admin0.50.71.1-0.40.70.8-0.60.91.0-1.0
Time to tail flick, vehicle, after self-admin1.93.95.52.4-2.2-2.12.3-1.8-1.41.4
Time to tail flick, test, before self-admin3.03.54.2-1.61.92.1-1.92.01.8-1.8
Time to tail flick, test, after self-admin0.91.02.40.30.30.7-0.21.11.5-1.6
Delta time to tail flick, vehicle, before/after SA1.01.11.91.4-1.3-1.11.3-0.9-0.60.5
Delta time to tail flick, test, before/after SA0.91.12.61.6-1.3-1.01.4-0.50.0-0.1
Tibia length3.59.817.6-4.23.93.3-3.42.71.8-1.8
Ambulatory time before self-admin0.10.20.5-0.70.30.0-0.3-0.2-0.60.6
Ambulatory time after self-admin3.25.26.31.7-2.2-2.42.0-2.5-2.52.5
Bone: tissue strength0.10.10.2-0.40.50.4-0.50.30.2-0.2
Total heroin consumption0.30.30.7-0.0-0.3-0.50.4-0.7-0.80.8
Bone: trabecular number1.83.43.9-1.71.92.0-1.72.01.9-1.9
Bone: trabecular spacing1.92.73.21.4-1.6-1.71.5-1.8-1.71.7
Bone: trabecular thickness1.31.82.1-1.41.51.4-1.31.41.2-1.2
Bone: trabecular tissue density0.61.11.90.5-0.8-1.00.8-1.2-1.41.4
Water consumed over 24 hours0.51.01.70.5-0.8-1.00.8-1.1-1.31.3
Number of responses in last shaping day0.30.40.70.4-0.5-0.70.7-0.7-0.80.8