Hub : Genes

Alg6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039110269.1 0.04 0.03 4.2e-05 0.02 0.03 0.03 0.03 3.5e-03 5.0e-04 7.0e-04 3.6e-04
2 Liver gene expression Alg6 0.22 0.13 2.0e-14 0.09 0.08 0.08 0.09 2.7e-10 1.4e-09 8.3e-09 2.6e-10
3 LHb alternative polyA XM_039110268.1 0.15 0.12 3.9e-03 0.06 0.06 0.05 0.05 1.2e-02 1.3e-02 2.3e-02 3.0e-02
4 Liver alternative polyA XM_039110269.1 0.04 0.03 8.6e-05 0.02 0.02 0.01 0.01 1.6e-03 3.3e-03 6.7e-02 7.9e-03
5 Liver alternative polyA XM_039110268.1 0.04 0.03 1.7e-04 0.02 0.02 0 0.01 5.1e-03 6.3e-03 1.4e-01 1.4e-02
6 PL alternative polyA XM_039110268.1 0.05 0.04 1.2e-06 0.07 0.06 0.06 0.06 9.3e-08 4.7e-07 1.3e-07 1.2e-07
7 PL alternative polyA XM_039110269.1 0.08 0.06 9.5e-10 0.1 0.09 0.1 0.1 4.5e-11 2.2e-10 1.1e-10 4.4e-11
8 PL alternative polyA XM_039110268.1 0.09 0.07 8.8e-10 0.1 0.09 0.1 0.1 4.4e-11 2.0e-10 4.9e-11 4.2e-11
9 NAcc alternative polyA XM_039110269.1 0.06 0.05 3.1e-06 0.05 0.05 0.04 0.05 1.9e-06 3.9e-06 1.4e-05 1.4e-06
10 NAcc alternative polyA XM_039110268.1 0.05 0.04 9.2e-06 0.05 0.04 0.04 0.05 8.2e-07 1.0e-05 4.9e-06 7.4e-07
11 LHb alternative polyA XM_039110268.1 0.21 0.18 3.2e-03 0.05 0.06 0.04 0.04 2.9e-02 1.2e-02 5.2e-02 3.6e-02
12 NAcc alternative polyA XM_039110269.1 0.04 0.03 1.0e-05 0.04 0.04 0.05 0.05 1.4e-05 6.8e-06 3.6e-06 4.3e-06
13 NAcc alternative polyA XM_039110268.1 0.04 0.03 6.3e-06 0.04 0.05 0.05 0.05 1.1e-05 4.5e-06 2.3e-06 2.4e-06
14 Adipose alternative polyA XM_039110269.1 0.04 0.03 9.5e-05 0.02 0.03 0.01 0.02 1.8e-03 8.6e-04 1.2e-02 1.1e-03
15 Brain alternative polyA XM_039110268.1 0.08 0.05 2.5e-10 0.1 0.11 0.11 0.1 1.1e-09 2.8e-10 4.0e-10 5.6e-10
16 Adipose alternative polyA XM_039110268.1 0.04 0.03 7.4e-05 0.02 0.03 0.01 0.03 1.5e-03 7.2e-04 9.9e-03 7.6e-04
17 Brain alternative polyA XM_039110269.1 0.08 0.05 2.5e-10 0.1 0.11 0.11 0.11 1.0e-09 2.7e-10 4.1e-10 5.1e-10
18 PL mRNA stability Alg6 0.05 0.04 1.1e-05 0.05 0.04 0.05 0.05 5.3e-06 1.6e-05 7.8e-06 7.5e-06
19 pVTA alternative polyA XM_039110268.1 0.12 0.07 7.4e-06 0.1 0.1 0.07 0.08 4.8e-05 2.8e-05 7.7e-04 2.1e-04
20 BLA alternative polyA XM_039110268.1 0.04 0.03 5.8e-03 0.02 0.01 0 0.01 2.5e-02 6.0e-02 2.4e-01 1.2e-01
21 BLA alternative polyA XM_039110269.1 0.04 0.03 6.2e-03 0.03 0.01 0 0.01 1.7e-02 5.3e-02 2.2e-01 1.1e-01
22 Brain mRNA stability Alg6 0.08 0.07 7.4e-06 0.07 0.06 0.06 0.07 4.5e-07 1.4e-06 1.4e-06 6.0e-07
23 pVTA alternative polyA XM_039110269.1 0.14 0.1 9.0e-05 0.06 0.08 0.06 0.05 1.5e-03 3.3e-04 1.2e-03 3.2e-03
24 pVTA alternative polyA XM_039110268.1 0.15 0.11 8.1e-05 0.06 0.08 0.06 0.05 1.3e-03 2.6e-04 8.9e-04 2.6e-03
25 Eye gene expression Alg6 0.27 0.17 5.4e-03 0.1 0.04 0.04 0.04 1.3e-02 7.3e-02 7.9e-02 7.9e-02
26 PL intron excision ratio chr5_114443858_114452985 0.08 0.06 1.3e-05 0.04 0.04 0.04 0.04 7.8e-05 1.5e-05 1.2e-05 4.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.10.20.4-0.60.4-0.50.5-0.5-0.4-0.30.3-0.10.00.60.3-0.3-0.40.40.4-0.40.50.4-0.40.40.5-0.20.2-0.50.1
Area under the delay curve0.20.21.0-0.40.5-0.61.0-0.9-0.5-0.50.5-0.40.40.40.4-0.5-0.40.30.4-0.30.40.3-0.50.50.3-0.20.2-0.20.4
BMI with tail0.10.51.20.6-0.81.1-1.01.00.70.8-0.80.5-0.5-0.9-0.70.70.6-0.6-0.60.6-0.7-0.40.7-0.7-0.60.2-0.10.5-0.1
BMI without tail0.30.61.00.4-0.80.7-1.01.00.80.8-0.80.7-0.7-0.7-0.70.70.7-0.7-0.70.7-0.8-0.70.8-0.8-0.70.7-0.70.8-0.8
Body weight0.00.10.4-0.20.20.30.3-0.4-0.1-0.10.1-0.30.30.10.2-0.2-0.30.30.3-0.30.30.5-0.20.20.3-0.60.6-0.20.6
Weight adjusted by age1.92.13.01.5-1.20.7-0.80.91.71.7-1.71.5-1.6-1.3-1.31.41.5-1.5-1.51.5-1.5-1.61.5-1.5-1.51.7-1.71.5-1.6
Bone surface1.73.03.61.9-1.71.6-1.31.31.71.7-1.71.9-1.9-1.7-1.81.81.7-1.9-1.81.9-1.8-1.71.8-1.8-1.81.8-1.81.9-1.5
Bone volume0.40.81.30.8-0.80.6-0.50.50.80.9-0.91.1-1.1-0.7-0.90.90.8-0.9-0.90.9-0.8-0.90.9-0.9-0.91.0-1.01.0-0.9
Breakpoint value in progressive ratio session0.80.91.8-0.70.9-0.30.3-0.2-1.2-1.01.0-1.21.20.51.2-1.2-0.80.70.8-0.71.10.9-1.11.10.8-1.11.1-0.81.3
Number of licking bursts0.00.00.20.2-0.20.3-0.50.40.1-0.00.0-0.10.1-0.20.1-0.10.1-0.1-0.10.10.1-0.1-0.20.20.3-0.00.00.20.1
Context. condit. distance diff. score3.13.85.9-2.02.0-1.51.9-1.9-1.9-1.91.9-2.02.11.61.8-1.8-2.01.82.0-1.81.92.1-1.91.91.8-2.22.2-1.82.4
Locomotion velocity, session 10.20.31.00.7-0.71.0-0.90.90.30.3-0.30.4-0.4-0.6-0.50.50.5-0.4-0.50.4-0.3-0.40.4-0.4-0.40.3-0.20.2-0.3
Locomotion distance, session 10.60.71.2-0.90.8-0.60.4-0.3-1.1-1.11.1-0.90.90.80.8-0.8-0.90.90.9-0.90.90.9-0.80.80.8-0.90.9-0.90.8
Locomotion velocity, session 20.10.10.3-0.1-0.1-0.10.5-0.50.10.1-0.10.4-0.40.1-0.40.40.2-0.2-0.20.2-0.4-0.30.4-0.4-0.30.5-0.50.2-0.5
Locomotion distance, session 20.20.30.60.5-0.40.5-0.50.50.20.2-0.20.5-0.5-0.4-0.40.40.5-0.4-0.50.4-0.8-0.60.7-0.7-0.60.6-0.60.5-0.7
Locomotion velocity, session 30.10.20.5-0.30.4-0.30.00.0-0.7-0.70.7-0.50.50.20.5-0.5-0.30.30.2-0.30.20.2-0.30.30.3-0.30.3-0.30.3
Locomotion distance, session 30.00.00.10.10.10.1-0.10.2-0.3-0.30.3-0.20.2-0.10.3-0.3-0.0-0.00.00.00.20.0-0.30.30.2-0.10.2-0.00.3
Stereotopy head waving bouts, day 30.80.91.5-1.11.2-1.01.1-1.1-1.1-1.11.1-1.01.01.01.1-1.1-0.90.90.9-0.90.90.8-0.80.80.7-0.80.7-0.60.9
Stereotopy head waving duration, day 31.01.22.0-1.41.3-1.11.4-1.4-1.2-1.21.2-1.01.01.31.1-1.0-1.11.21.1-1.20.91.0-0.80.80.9-0.80.8-1.00.7
Locomotion velocity, session 71.21.31.8-1.21.3-0.81.1-1.1-1.3-1.31.3-1.31.31.11.3-1.3-1.11.11.1-1.10.91.0-1.01.00.9-1.01.0-0.91.1
Locomotion distance, session 70.60.71.3-1.10.9-0.80.8-0.7-0.8-0.80.8-0.90.90.80.8-0.9-0.80.80.8-0.80.90.8-1.01.00.9-0.80.8-0.80.8
Stereotopy head waving bouts, day 70.70.81.91.1-0.81.4-0.60.60.80.8-0.80.8-0.9-0.9-0.80.80.9-0.9-0.90.9-0.9-0.91.0-1.0-0.90.8-0.80.9-0.6
Stereotopy head waving duration, day 71.21.52.81.5-1.11.7-1.11.11.11.1-1.11.1-1.2-1.2-1.01.01.2-1.2-1.21.2-1.3-1.21.3-1.3-1.21.2-1.21.1-1.2
Locomotion velocity, session 80.30.30.5-0.50.60.30.4-0.4-0.7-0.70.7-0.70.70.50.6-0.6-0.50.60.5-0.60.50.6-0.50.50.5-0.70.7-0.70.7
Locomotion distance, session 80.81.21.6-1.21.0-0.90.7-0.7-1.3-1.31.3-1.11.11.01.0-1.0-1.11.11.1-1.11.11.1-1.11.11.0-1.21.2-1.11.1
Degree of sensitization distance0.00.00.0-0.2-0.10.1-0.00.00.20.2-0.20.1-0.0-0.1-0.20.20.0-0.1-0.00.1-0.10.00.2-0.2-0.10.0-0.00.10.0
Degree of sensitization stereotypy1.21.32.41.5-1.11.6-1.01.01.11.1-1.11.1-1.2-1.1-1.01.01.2-1.1-1.21.1-1.2-1.11.2-1.2-1.11.1-1.11.0-1.1
Conditioned locomotion0.10.10.3-0.20.20.2-0.10.2-0.2-0.30.3-0.50.50.10.4-0.4-0.30.30.3-0.30.00.30.0-0.0-0.0-0.50.5-0.30.4
Cocaine response after cond. corrected0.40.51.61.0-0.71.2-1.31.30.50.5-0.50.5-0.5-0.7-0.30.30.7-0.6-0.70.6-0.5-0.70.5-0.5-0.50.6-0.50.7-0.6
Cocaine response after cond. not corrected0.40.41.81.0-0.61.3-1.21.20.40.4-0.40.4-0.4-0.6-0.20.20.6-0.5-0.60.5-0.4-0.60.3-0.3-0.30.5-0.40.6-0.4
Cocaine response before conditioning0.00.00.00.10.00.10.1-0.1-0.10.0-0.00.0-0.00.10.0-0.00.00.0-0.0-0.00.2-0.0-0.20.20.20.0-0.0-0.10.0
Saline control response0.00.00.2-0.0-0.10.1-0.10.10.10.1-0.10.1-0.10.1-0.10.1-0.00.10.0-0.10.10.0-0.10.10.1-0.00.0-0.4-0.1
Bone: connectivity density2.13.34.21.9-1.81.8-1.61.71.81.8-1.82.0-2.0-1.7-1.91.91.8-1.8-1.81.8-1.8-1.81.8-1.8-1.61.8-1.81.8-1.8
Bone: cortical apparent density7.59.913.8-3.53.1-3.72.6-2.6-3.2-3.23.2-3.13.13.43.2-3.2-3.23.33.2-3.33.23.1-3.23.23.4-2.92.9-3.22.5
Bone: cortical area0.20.30.80.4-0.70.3-0.50.50.60.6-0.60.7-0.7-0.4-0.70.70.5-0.5-0.50.5-0.5-0.60.5-0.5-0.70.7-0.70.4-0.9
Bone: cortical porosity0.60.61.31.0-0.91.2-0.80.80.90.8-0.80.8-0.8-0.9-0.90.90.8-0.8-0.80.8-0.6-0.70.6-0.6-0.80.7-0.60.6-0.6
Bone: cortical porosity0.91.02.31.1-1.11.5-1.01.01.01.1-1.11.0-0.9-1.1-1.11.11.0-1.0-0.91.0-0.8-0.90.8-0.8-1.00.7-0.70.7-0.7
Bone: cortical thickness0.10.20.5-0.70.3-0.50.3-0.3-0.2-0.30.3-0.40.40.50.3-0.3-0.50.60.5-0.60.60.5-0.60.60.5-0.50.5-0.70.3
Bone: cortical thickness0.00.10.3-0.50.2-0.10.3-0.2-0.0-0.10.1-0.20.20.20.1-0.1-0.30.20.3-0.20.10.30.0-0.0-0.0-0.30.3-0.20.3
Bone: cortical tissue density7.49.713.4-3.43.0-3.72.6-2.5-3.1-3.23.2-3.13.03.43.2-3.2-3.23.33.2-3.33.13.0-3.13.13.3-2.92.8-3.22.5
Condit. Reinf. active minus inactive responses0.60.72.00.8-1.10.8-1.41.40.60.7-0.70.8-0.7-0.7-0.90.90.7-0.6-0.70.6-0.9-0.70.8-0.8-0.70.7-0.60.6-0.8
Condit. Reinf. active-inactive response ratio0.20.21.30.6-0.60.8-1.11.20.20.3-0.30.3-0.2-0.4-0.30.30.3-0.2-0.30.2-0.5-0.30.4-0.4-0.30.1-0.10.2-0.3
Condit. Reinf. active responses1.51.84.01.4-1.61.3-2.02.01.11.2-1.21.3-1.3-1.3-1.41.41.3-1.2-1.31.2-1.4-1.21.3-1.3-1.31.2-1.21.1-1.3
Condit. Reinf. inactive responses0.70.81.60.8-1.00.9-1.31.30.70.7-0.70.9-0.9-0.8-0.90.90.9-0.8-0.90.8-0.9-0.80.9-0.9-0.90.8-0.80.5-0.8
Incentive salience index mean0.91.13.11.0-1.41.2-1.71.80.90.9-0.91.0-1.0-0.9-1.11.10.9-0.8-0.90.8-1.1-0.91.0-1.0-1.00.8-0.80.7-1.0
Condit. Reinf. lever presses0.10.21.20.2-0.60.9-1.11.10.20.3-0.30.3-0.3-0.2-0.50.50.2-0.0-0.20.0-0.3-0.10.2-0.2-0.30.0-0.0-0.2-0.3
Condit. Reinf. active minus inactive responses0.70.91.4-1.00.9-0.60.9-0.9-0.8-0.90.9-0.90.91.11.0-1.0-1.01.11.0-1.10.91.0-0.90.91.0-1.01.0-1.20.9
Condit. Reinf. active-inactive response ratio0.20.20.5-0.40.3-0.10.2-0.2-0.3-0.40.4-0.40.40.50.4-0.4-0.40.60.4-0.60.30.4-0.30.30.4-0.40.4-0.70.2
Condit. Reinf. active responses0.40.50.9-0.60.7-0.30.7-0.7-0.5-0.60.6-0.70.70.80.7-0.7-0.70.80.8-0.80.70.8-0.70.70.7-0.80.8-0.90.8
Condit. Reinf. inactive responses0.91.11.4-1.01.1-0.91.1-1.1-0.9-0.90.9-1.01.01.11.1-1.1-1.11.11.1-1.11.21.1-1.11.11.0-1.11.0-1.21.1
Condit. Reinf. lever presses3.54.85.92.4-2.32.2-2.22.22.22.2-2.22.2-2.2-2.1-2.12.12.2-2.1-2.22.1-2.3-2.22.3-2.3-2.22.1-2.12.0-2.1
Condit. Reinf. lever reinforcers received0.10.10.3-0.10.20.10.3-0.3-0.1-0.20.2-0.20.20.40.3-0.3-0.30.30.3-0.30.30.3-0.20.20.2-0.30.3-0.50.4
Conditioned reinforcement - actives0.10.10.6-0.2-0.10.0-0.80.70.0-0.10.10.0-0.00.3-0.00.0-0.20.30.2-0.3-0.00.10.1-0.1-0.2-0.10.1-0.3-0.1
Conditioned reinforcement - inactives0.20.20.8-0.50.50.40.2-0.2-0.2-0.40.4-0.50.60.30.4-0.4-0.50.40.5-0.40.50.6-0.50.50.4-0.80.8-0.40.9
Conditioned locomotion0.10.10.60.0-0.30.6-0.80.70.40.0-0.0-0.00.0-0.1-0.10.1-0.10.20.1-0.2-0.10.10.1-0.1-0.2-0.20.3-0.4-0.0
Patch foraging indifference point 0 sec7.211.618.23.9-3.64.3-3.53.53.73.5-3.53.3-3.3-3.6-3.43.43.4-3.5-3.43.5-3.2-3.23.2-3.2-3.33.0-3.03.1-2.7
Patch foraging indifference point AUC1.21.42.71.3-1.31.1-1.61.51.31.1-1.11.1-1.1-1.0-1.21.21.2-1.1-1.21.1-1.1-1.21.1-1.1-0.91.3-1.31.1-1.4
Delay disc. indifference point, 0s delay3.13.36.0-1.82.1-1.52.5-2.4-1.6-1.61.6-1.81.81.61.7-1.7-1.81.71.8-1.71.81.9-1.81.81.7-1.91.9-1.62.0
Delay disc. indifference point, 16s delay1.51.52.21.4-1.31.4-1.51.41.11.0-1.01.1-1.0-1.3-1.11.11.3-1.3-1.31.3-1.1-1.31.1-1.1-1.31.2-1.21.3-1.0
Delay disc. indifference point, 2s delay0.60.63.0-0.51.1-0.81.7-1.6-0.6-0.70.7-0.70.70.50.8-0.8-0.60.40.6-0.40.70.7-0.60.60.3-0.70.7-0.21.0
Delay disc. indifference point, 24s delay0.00.00.20.1-0.10.1-0.20.4-0.4-0.30.3-0.20.20.10.2-0.2-0.00.10.0-0.10.2-0.0-0.20.20.1-0.00.0-0.1-0.0
Delay disc. indifference point, 4s delay2.32.45.3-1.81.7-2.12.2-2.3-1.7-1.61.6-1.31.41.61.3-1.3-1.51.41.5-1.41.41.4-1.41.41.3-1.21.2-1.31.2
Delay disc. indifference point, 8s delay1.11.22.0-1.11.1-1.21.4-1.3-1.1-1.21.2-1.01.01.11.0-1.0-1.01.11.0-1.11.11.0-1.21.21.1-0.90.9-1.00.9
Indifference point function ln k0.71.01.8-1.31.0-1.31.4-1.2-1.0-0.90.9-0.90.90.80.9-0.9-1.00.81.0-0.90.91.0-0.80.80.8-1.01.0-0.81.1
Indifference point function log k0.71.01.8-1.31.0-1.31.4-1.2-1.0-0.90.9-0.90.90.80.9-0.9-1.00.81.0-0.90.91.0-0.80.80.8-1.01.0-0.81.1
Patch foraging total patch changes 0 sec6.710.816.93.8-3.54.1-3.43.43.63.4-3.43.2-3.2-3.5-3.33.33.3-3.3-3.33.3-3.1-3.13.1-3.1-3.12.9-2.82.9-2.5
Patch foraging total patch changes 12 sec1.82.35.02.0-1.62.2-1.91.81.51.3-1.31.3-1.3-1.6-1.31.31.6-1.5-1.61.5-1.4-1.51.3-1.3-1.41.3-1.31.3-1.2
Patch foraging total patch changes 18 sec3.64.69.22.5-2.43.0-2.52.42.52.3-2.32.1-2.0-2.3-2.22.22.1-2.1-2.12.1-2.0-1.91.9-1.9-1.91.7-1.71.7-1.6
Patch foraging total patch changes 24 sec1.72.14.62.0-1.52.1-1.81.61.71.4-1.41.3-1.3-1.7-1.41.41.5-1.5-1.41.4-1.4-1.31.3-1.3-1.51.0-1.01.2-0.7
Patch foraging total patch changes 6 sec4.46.513.12.9-3.03.3-3.63.62.82.5-2.52.5-2.5-2.5-2.42.42.5-2.3-2.52.3-2.2-2.42.2-2.2-2.12.2-2.11.9-2.2
Patch foraging time to switch 0 sec1.21.92.8-1.31.3-1.31.0-1.0-1.7-1.51.5-1.51.41.51.6-1.6-1.41.51.4-1.51.51.2-1.51.51.4-1.21.2-1.50.8
Patch foraging water rate 0 sec1.52.43.01.7-1.61.5-1.51.41.71.5-1.51.6-1.6-1.6-1.71.61.6-1.6-1.61.6-1.6-1.51.6-1.6-1.61.5-1.51.7-1.3
Patch foraging water rate 12 sec2.94.55.92.1-2.22.4-2.02.02.22.1-2.12.1-2.0-2.4-2.22.22.1-2.3-2.12.3-2.2-1.92.3-2.3-2.21.7-1.72.3-1.3
Patch foraging water rate 18 sec0.30.51.20.9-0.90.8-1.11.10.60.5-0.50.6-0.5-0.9-0.60.60.7-0.7-0.60.7-0.6-0.50.6-0.6-0.70.3-0.30.7-0.1
Patch foraging water rate 24 sec0.00.10.20.1-0.30.1-0.40.40.30.2-0.20.1-0.1-0.4-0.20.20.1-0.2-0.10.2-0.2-0.00.2-0.2-0.2-0.20.20.30.4
Patch foraging water rate 6 sec0.10.10.3-0.1-0.10.00.3-0.30.30.3-0.30.4-0.3-0.2-0.40.40.1-0.2-0.10.2-0.5-0.10.5-0.5-0.40.1-0.10.3-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.80.1-0.00.30.6-0.50.20.2-0.20.10.0-0.6-0.30.20.1-0.3-0.00.3-0.00.20.2-0.2-0.2-0.40.40.30.9
Distance traveled before self-admin0.00.00.10.1-0.20.20.1-0.20.2-0.00.00.00.0-0.4-0.30.30.2-0.3-0.20.3-0.1-0.10.1-0.1-0.10.00.00.30.2
Distance traveled after self-admin0.91.01.51.2-1.01.1-0.91.01.00.9-0.90.9-0.9-1.1-0.90.91.1-1.1-1.11.1-0.8-1.10.9-0.9-1.11.1-1.11.2-0.9
Extensor digitorum longus weight0.52.13.8-1.51.3-0.51.1-1.2-1.4-1.41.4-1.51.51.11.5-1.5-1.51.41.5-1.41.41.6-1.41.41.4-1.91.9-1.52.0
Bone: elastic displacement0.60.70.9-0.90.7-0.80.9-0.9-0.8-0.80.8-0.80.80.80.6-0.6-0.90.90.9-0.90.80.9-0.80.80.8-1.00.9-0.90.9
Bone: elastic work1.01.31.7-1.31.1-1.01.2-1.2-1.1-1.11.1-1.11.11.10.9-0.9-1.21.21.2-1.21.11.2-1.01.01.0-1.21.2-1.21.2
Bone: endosteal estimation0.40.81.21.0-0.80.9-0.70.70.70.8-0.81.0-0.9-1.0-1.01.00.9-1.1-0.91.1-1.0-0.91.0-1.0-1.10.9-0.91.1-0.7
Bone: endosteal perimeter1.22.63.41.8-1.51.5-1.01.01.41.5-1.51.8-1.8-1.4-1.71.71.6-1.7-1.61.7-1.6-1.71.6-1.6-1.61.8-1.81.7-1.8
Epididymis fat weight1.74.14.9-2.11.9-1.51.6-1.6-1.9-1.91.9-2.12.22.02.0-2.0-2.22.22.2-2.22.02.2-2.12.12.0-2.22.2-2.01.8
Delta time in closed arm before/after self-admin0.20.20.90.6-0.31.0-0.80.40.50.5-0.50.2-0.1-0.6-0.20.20.4-0.4-0.40.4-0.4-0.30.4-0.4-0.50.1-0.10.30.1
Delta time in open arm before/after self-admin1.51.42.80.8-1.30.3-0.61.11.21.3-1.31.4-1.5-0.8-1.31.31.1-1.1-1.11.1-1.2-1.31.1-1.1-0.91.5-1.51.1-1.7
Diff in mean of infusions in LGA sessions0.40.51.3-0.40.60.10.2-0.4-0.9-0.60.6-0.80.90.40.7-0.7-0.60.60.6-0.60.70.7-0.80.80.6-0.90.9-0.61.1
Delay discount exponential model param0.20.20.80.3-0.50.6-0.90.80.50.5-0.50.4-0.4-0.4-0.40.40.3-0.3-0.30.3-0.4-0.30.4-0.4-0.30.2-0.20.2-0.3
Extinction: sum of active levers before priming1.01.02.4-1.31.3-0.81.4-1.6-0.8-0.80.8-1.01.00.61.0-1.0-0.90.60.9-0.60.80.9-1.01.00.7-1.01.0-0.61.3
Active lever presses in extinction session 60.10.10.60.1-0.10.4-0.60.4-0.3-0.00.0-0.30.4-0.30.1-0.1-0.1-0.00.1-0.00.20.3-0.20.20.3-0.60.6-0.30.8
Bone: final force0.40.71.1-1.10.9-0.70.8-0.8-0.9-1.01.0-0.80.81.00.9-0.9-0.80.90.8-0.90.90.8-0.90.90.8-0.70.7-0.80.5
Bone: final moment0.00.00.1-0.30.2-0.00.2-0.2-0.2-0.30.3-0.20.20.30.2-0.2-0.20.20.2-0.20.30.2-0.20.20.1-0.10.1-0.20.0
Food consumed during 24 hour testing period0.40.41.9-0.50.6-1.40.6-0.6-0.8-0.80.8-0.60.60.70.8-0.8-0.60.50.5-0.50.70.4-0.70.70.7-0.30.3-0.30.3
Glucose0.10.10.80.3-0.30.9-0.50.50.40.4-0.40.1-0.1-0.3-0.20.20.2-0.1-0.10.10.10.0-0.10.10.0-0.20.2-0.10.2
Heart weight3.34.65.8-2.02.1-1.71.5-1.7-2.3-2.42.4-2.22.22.12.1-2.1-2.22.22.2-2.22.22.3-2.02.02.1-2.42.4-2.22.4
Delay discount hyperbolic model param0.40.41.40.5-0.70.8-1.21.10.70.7-0.70.6-0.6-0.6-0.60.60.5-0.5-0.50.5-0.6-0.50.6-0.6-0.40.4-0.40.3-0.5
Intermittent access intake day 1-15 change0.80.81.6-1.31.0-1.00.4-0.8-0.8-0.90.9-0.80.81.31.0-1.0-0.91.10.8-1.10.90.7-0.90.91.0-0.50.4-0.80.1
Intermittent access intake escalation0.70.71.4-1.10.9-0.90.2-0.6-0.7-0.90.9-0.80.71.20.9-0.9-0.81.00.8-1.01.00.6-0.90.90.9-0.40.4-0.80.0
Intermittent access intake escalation 20.80.81.3-1.00.9-0.60.1-0.5-0.6-0.80.8-0.90.81.11.2-1.2-0.81.00.8-1.01.10.7-1.11.11.1-0.70.6-0.90.4
Intermitt. access day 1 inactive lever presses1.01.11.91.0-1.01.0-0.50.41.21.1-1.11.1-1.1-1.4-1.31.31.0-1.3-1.01.2-1.2-0.81.2-1.2-1.00.7-0.71.2-0.3
Intermitt. access day 15 inactive lever presses0.90.91.4-1.21.0-0.81.0-1.1-0.7-1.01.0-0.90.90.90.9-0.9-1.00.91.0-0.90.91.0-0.90.90.9-1.11.1-1.01.1
Intermitt. access escalation Index0.60.51.60.5-0.3-1.20.6-0.50.40.6-0.60.9-1.0-0.1-0.50.50.6-0.6-0.60.6-0.6-0.80.5-0.5-0.41.2-1.30.6-1.2
Intermittent access day 1 total infusions0.10.10.40.2-0.5-0.1-0.40.70.20.2-0.20.3-0.3-0.1-0.30.30.1-0.0-0.10.0-0.2-0.10.2-0.2-0.20.1-0.1-0.2-0.3
Intermittent access day 15 total infusions0.20.30.6-0.70.3-0.6-0.30.3-0.3-0.60.6-0.40.40.80.5-0.5-0.50.70.5-0.70.60.4-0.50.50.5-0.20.2-0.7-0.2
Intermittent access terminal intake (last 3 days)0.00.00.1-0.3-0.0-0.2-0.40.30.0-0.10.1-0.10.10.30.1-0.1-0.20.30.2-0.30.00.1-0.00.0-0.0-0.00.0-0.2-0.2
Intermittent access total infusions0.10.10.4-0.4-0.1-0.1-0.50.6-0.2-0.40.4-0.20.20.40.1-0.2-0.30.50.3-0.50.30.3-0.30.30.2-0.20.2-0.6-0.2
Intermittent access day 1 locomotion0.60.72.80.9-1.20.5-1.51.70.70.7-0.70.8-0.8-0.6-0.80.80.7-0.5-0.70.5-0.7-0.70.7-0.7-0.60.7-0.70.3-1.0
Intermittent access day 15 total locomotion0.50.61.80.5-1.00.2-1.31.11.10.9-0.90.8-0.8-0.4-0.80.80.6-0.3-0.60.4-0.7-0.60.7-0.7-0.80.7-0.70.2-1.1
Intermittent access total locomotion0.30.41.80.5-0.90.2-1.31.30.60.4-0.40.5-0.5-0.3-0.60.60.4-0.2-0.40.2-0.5-0.40.5-0.5-0.50.5-0.50.1-0.8
Intermittent access standard deviation0.80.81.6-1.10.6-0.3-0.1-0.1-0.8-1.01.0-1.00.91.00.9-0.9-1.01.21.0-1.21.00.9-1.01.00.9-0.91.0-1.30.4
Left kidney weight0.51.53.9-0.61.3-0.10.7-0.9-1.3-1.31.3-1.51.50.71.4-1.4-1.11.01.1-1.01.31.3-1.11.11.1-1.61.7-0.92.0
Right kidney weight0.61.73.9-1.01.5-0.81.4-1.5-1.4-1.41.4-1.41.40.91.4-1.4-1.21.01.2-1.01.31.4-1.21.21.0-1.51.6-0.72.0
Cocaine induced anxiety0.20.20.6-0.40.4-0.30.7-0.5-0.8-0.70.7-0.20.10.70.4-0.4-0.40.40.3-0.40.30.1-0.30.30.20.1-0.1-0.1-0.4
Post-drug Anxiety1.31.52.9-1.41.4-1.11.5-1.4-1.7-1.41.4-1.21.11.41.3-1.3-1.21.21.2-1.21.11.1-1.11.11.0-0.90.9-0.80.8
Baseline Anxiety0.70.71.7-0.91.0-0.70.9-1.1-0.5-0.50.5-0.91.00.60.8-0.8-0.80.70.8-0.70.81.0-0.80.80.7-1.11.1-0.91.3
Tail length0.61.82.5-1.51.5-1.51.5-1.6-1.3-1.41.5-1.31.21.51.4-1.4-1.31.31.3-1.31.51.1-1.41.41.3-0.90.9-1.10.8
Length with tail0.41.42.6-1.11.2-1.11.5-1.6-1.1-1.31.3-1.11.11.21.2-1.2-1.21.11.2-1.11.41.2-1.21.21.0-1.11.0-1.01.1
Length without tail0.00.10.50.10.2-0.00.6-0.7-0.2-0.20.2-0.20.2-0.00.1-0.1-0.20.10.3-0.10.30.4-0.20.2-0.0-0.50.5-0.10.7
Times rat made contact with spout0.10.10.60.5-0.60.5-0.80.80.20.2-0.20.2-0.2-0.4-0.20.20.3-0.2-0.30.20.2-0.2-0.20.20.20.00.00.0-0.0
Lifetime Intake0.10.10.5-0.1-0.30.1-0.50.70.1-0.10.10.2-0.20.2-0.20.2-0.00.2-0.0-0.2-0.1-0.10.1-0.1-0.10.2-0.3-0.3-0.6
Liver weight, left1.93.14.3-2.01.9-1.72.1-2.0-1.7-1.81.8-1.71.71.71.6-1.6-1.81.71.8-1.71.81.8-1.61.61.6-1.71.7-1.51.7
Liver weight, right6.310.413.1-3.33.2-2.43.1-3.1-3.2-3.23.2-3.43.42.93.2-3.2-3.23.13.3-3.23.13.4-3.23.23.1-3.53.6-3.23.6
Locomotor activity0.10.20.40.2-0.50.6-0.10.10.60.7-0.70.5-0.5-0.3-0.50.60.3-0.3-0.30.3-0.5-0.20.5-0.5-0.30.3-0.30.3-0.3
Locomotor testing distance1.93.24.51.9-1.82.1-1.41.51.91.9-1.91.8-1.8-1.8-1.81.81.8-1.8-1.81.8-1.8-1.71.9-1.9-1.81.6-1.61.8-1.4
Locomotor testing rearing0.10.10.70.5-0.40.8-0.50.40.60.5-0.50.2-0.2-0.3-0.30.30.3-0.2-0.30.2-0.1-0.20.1-0.1-0.10.1-0.10.1-0.2
Locomotion in novel chamber0.60.71.21.1-0.71.0-1.00.80.90.9-0.90.6-0.6-1.1-0.60.60.9-1.0-0.91.0-0.7-0.80.8-0.8-0.70.7-0.60.9-0.3
Locomotion in novel chamber post-restriction0.10.10.4-0.1-0.40.3-0.60.6-0.00.1-0.1-0.10.10.1-0.00.0-0.10.20.1-0.20.10.0-0.40.40.4-0.00.0-0.6-0.3
Fecal boli incidents, locomotor time 10.00.00.3-0.2-0.10.2-0.50.50.1-0.20.2-0.10.10.10.1-0.10.00.1-0.0-0.10.2-0.1-0.10.10.00.1-0.1-0.1-0.3
Change in fecal boli incidents, locomotor task0.20.21.3-0.50.4-0.80.9-1.1-0.3-0.20.2-0.10.20.40.1-0.1-0.40.30.4-0.3-0.00.4-0.10.10.2-0.30.3-0.20.4
Time >=10cm from walls, locomotor time 10.20.30.50.2-0.40.2-0.1-0.10.40.3-0.30.6-0.6-0.4-0.60.60.5-0.6-0.50.6-0.5-0.50.6-0.6-0.50.6-0.60.7-0.6
Bouts of movement, locomotor time 10.30.41.80.5-0.51.3-0.70.70.61.0-1.00.3-0.3-0.9-0.50.50.4-0.5-0.40.5-0.5-0.20.5-0.5-0.4-0.10.10.40.3
Total resting periods, locomotor time 10.30.31.80.7-0.51.4-0.50.50.60.9-0.90.4-0.4-0.9-0.40.40.5-0.6-0.50.6-0.4-0.30.5-0.5-0.40.00.00.50.3
Rest time, locomotor task time 10.00.00.2-0.10.00.00.4-0.4-0.10.3-0.30.2-0.2-0.2-0.20.20.1-0.3-0.10.3-0.1-0.00.2-0.2-0.30.0-0.00.30.2
Distance moved, locomotor task time 10.20.20.5-0.60.4-0.60.3-0.4-0.4-0.50.5-0.50.50.60.4-0.4-0.40.50.4-0.50.50.4-0.50.50.7-0.30.3-0.60.2
Vertical activity count, locomotor time 10.10.10.6-0.2-0.0-0.80.5-0.5-0.2-0.30.30.1-0.00.2-0.20.2-0.10.00.1-0.0-0.2-0.00.1-0.1-0.00.2-0.20.0-0.3
Time >=10cm from walls, locomotor time 22.72.94.4-1.81.8-1.31.8-2.0-1.9-2.12.1-1.61.61.51.6-1.6-1.61.51.6-1.61.61.7-1.61.61.7-1.71.7-1.51.7
Bouts of movement, locomotor time 21.31.42.11.4-1.51.1-1.11.01.31.3-1.31.3-1.2-1.3-1.31.31.1-1.1-1.11.1-1.2-1.01.2-1.2-0.90.9-0.91.1-0.9
Total resting periods, locomotor time 21.31.42.01.4-1.41.1-1.01.01.31.3-1.31.2-1.2-1.2-1.31.31.1-1.2-1.11.2-1.2-1.11.2-1.2-1.01.0-1.01.2-0.9
Rest time, locomotor task time 20.60.61.10.7-0.80.1-0.20.40.81.1-1.10.9-0.8-0.8-0.90.90.7-0.9-0.70.9-0.9-0.70.8-0.8-0.90.8-0.80.9-0.6
Distance moved, locomotor task time 22.42.83.6-1.71.9-1.01.4-1.5-1.9-1.71.7-1.71.71.61.7-1.7-1.61.61.6-1.61.71.6-1.71.71.9-1.71.7-1.81.7
Vertical activity count, locomotor time 20.91.01.7-1.31.0-0.71.1-1.2-1.2-1.11.1-0.90.90.90.8-0.8-1.01.01.0-1.01.01.0-0.90.91.0-1.11.1-1.01.0
Light reinforcement 10.20.40.8-0.60.40.10.1-0.1-0.3-0.50.5-0.80.80.40.6-0.6-0.60.60.6-0.60.70.7-0.70.70.8-0.80.8-0.70.9
Light reinforcement 20.40.50.8-0.80.8-0.40.5-0.5-0.6-0.70.7-0.90.90.60.7-0.7-0.80.70.8-0.70.80.8-0.80.80.7-0.80.8-0.70.9
Bone: marrow area0.30.71.10.9-0.80.9-0.70.60.60.7-0.70.9-0.9-0.9-0.90.90.9-1.0-0.91.0-1.0-0.90.9-0.9-1.00.9-0.91.0-0.6
Bone: maximum diameter0.71.32.21.1-1.20.9-1.01.01.01.0-1.01.2-1.2-0.9-1.21.21.1-1.1-1.11.1-1.1-1.21.1-1.1-1.21.3-1.31.1-1.5
Bone: maximum force0.10.20.3-0.50.4-0.20.3-0.3-0.5-0.50.5-0.40.30.40.4-0.4-0.30.40.3-0.40.50.3-0.50.50.3-0.30.3-0.40.1
Bone: maximum moment0.10.10.30.3-0.30.5-0.30.40.20.2-0.20.3-0.3-0.3-0.30.40.3-0.3-0.30.3-0.2-0.30.2-0.2-0.30.3-0.30.2-0.3
Mean time between licks in bursts5.98.310.7-3.23.3-2.73.2-3.2-2.9-2.92.9-2.82.82.92.9-2.9-2.92.92.9-2.92.52.9-2.62.62.7-2.82.8-2.72.8
Mean num. licks in bursts0.10.10.20.2-0.30.1-0.20.20.20.3-0.30.4-0.4-0.2-0.40.40.2-0.2-0.20.2-0.2-0.20.3-0.3-0.30.2-0.2-0.0-0.3
Cd content in liver1.51.63.91.3-1.52.0-1.21.11.51.4-1.41.3-1.3-1.5-1.41.41.2-1.3-1.21.3-1.2-1.01.2-1.2-1.30.9-0.81.1-0.6
Co content in liver0.30.31.6-0.40.50.40.7-0.7-0.4-0.40.4-0.60.60.10.5-0.5-0.50.30.6-0.40.30.7-0.40.40.5-0.90.9-0.51.2
Cu content in liver0.30.30.5-0.50.5-0.10.4-0.4-0.6-0.70.7-0.70.70.50.7-0.7-0.60.60.6-0.60.50.6-0.60.60.6-0.60.7-0.60.6
Fe content in liver0.91.11.61.1-1.20.8-0.80.81.31.1-1.11.2-1.2-1.1-1.21.21.0-1.1-1.01.1-1.0-1.01.1-1.1-1.20.9-0.91.0-0.8
K content in liver1.31.32.1-1.31.3-1.51.0-1.0-1.3-1.21.2-1.21.21.21.2-1.2-1.21.11.1-1.11.01.1-1.01.01.0-1.01.0-1.01.0
Mg content in liver0.40.41.40.6-0.40.2-0.70.70.30.4-0.40.5-0.6-0.2-0.40.40.6-0.4-0.60.5-0.5-0.80.5-0.5-0.51.0-1.00.6-1.2
Mn content in liver0.10.10.2-0.40.2-0.1-0.10.1-0.3-0.30.3-0.40.40.10.4-0.4-0.30.30.3-0.30.40.3-0.30.30.3-0.40.4-0.30.4
Na content in liver3.63.75.8-2.12.0-2.42.1-2.2-2.0-2.02.0-1.91.92.01.9-1.9-2.01.92.0-1.91.91.9-1.81.81.7-1.81.8-1.81.8
Rb content in liver0.60.81.0-0.90.7-0.70.3-0.4-0.8-0.90.9-0.90.90.91.0-1.0-0.90.90.9-0.90.90.9-0.90.91.0-0.90.9-0.90.8
Se content in liver0.70.91.41.0-0.80.8-0.60.60.90.8-0.80.8-0.8-1.1-0.90.90.9-1.1-0.91.1-1.1-0.91.1-1.1-1.10.8-0.81.2-0.5
Sr content in liver0.10.10.10.3-0.20.2-0.30.30.20.2-0.20.2-0.2-0.4-0.20.20.2-0.3-0.20.3-0.2-0.20.2-0.2-0.20.1-0.10.20.0
Zn content in liver0.80.91.41.0-1.01.0-1.11.10.90.8-0.80.8-0.9-0.7-0.80.80.9-0.8-0.90.8-0.9-1.00.9-0.9-0.81.0-1.00.7-1.2
Bone: minimum diameter1.63.03.81.8-1.81.5-1.41.41.71.7-1.71.9-1.9-1.6-1.91.91.7-1.7-1.71.7-1.7-1.71.7-1.7-1.91.8-1.81.7-1.8
Time in familiar zone, hab. session 12.72.53.1-1.61.6-0.71.5-1.5-1.7-1.71.7-1.71.71.41.5-1.5-1.61.61.6-1.61.41.7-1.51.51.5-1.81.8-1.61.7
Time in novel zone, hab. session 16.46.37.02.6-2.51.9-2.22.22.72.7-2.72.6-2.6-2.4-2.52.52.5-2.5-2.52.5-2.4-2.62.5-2.5-2.52.6-2.62.6-2.6
Total zone transitions, hab. session 11.21.72.1-1.31.3-1.20.7-0.7-1.3-1.31.3-1.41.41.31.4-1.4-1.31.31.3-1.31.41.2-1.41.41.4-1.21.2-1.31.1
Total locomotion distance, hab. session 10.20.30.9-0.80.8-0.90.7-0.7-0.7-0.70.7-0.60.60.50.6-0.6-0.60.40.6-0.40.40.5-0.40.40.3-0.50.5-0.20.7
Locomotion velocity, hab. session 10.20.30.7-0.70.7-0.90.5-0.5-0.7-0.70.7-0.60.60.60.7-0.7-0.60.50.6-0.50.50.5-0.40.40.4-0.50.5-0.30.6
Time in familiar zone, hab. session 20.50.61.3-0.50.4-0.20.1-0.1-0.7-0.70.7-0.80.80.50.7-0.7-0.70.70.7-0.70.90.7-1.11.11.2-0.91.0-0.80.8
Time in novel zone, hab. session 21.01.01.80.9-0.70.7-0.40.41.01.0-1.01.0-1.0-0.8-1.01.00.9-1.0-0.91.0-1.1-1.01.3-1.3-1.31.1-1.11.0-1.0
Total zone transitions, hab. session 25.67.29.4-2.82.8-2.72.3-2.2-3.1-3.13.1-2.82.82.82.9-2.9-2.72.72.7-2.72.72.6-2.52.52.5-2.52.5-2.52.3
Total locomotion distance, hab. session 23.44.56.1-2.32.4-2.22.1-2.0-2.5-2.52.5-2.22.22.22.2-2.2-2.12.12.1-2.12.02.0-1.81.81.8-1.91.9-1.81.9
Locomotion velocity, hab. session 22.93.95.9-2.12.3-2.12.0-1.9-2.4-2.42.4-2.12.02.12.1-2.1-2.01.92.0-1.91.81.8-1.61.61.6-1.71.7-1.61.7
Novel to familiar place preference ratio1.21.21.61.1-1.20.9-0.90.91.31.3-1.31.2-1.1-1.1-1.21.21.1-1.1-1.11.1-0.9-1.11.0-1.0-1.01.1-1.11.0-1.1
Novelty place preference0.70.71.10.8-0.90.6-0.60.61.01.0-1.00.9-0.9-0.8-1.01.00.9-0.8-0.90.8-0.7-0.80.8-0.8-0.70.8-0.80.7-0.8
Time in novel zone, NPP test0.90.91.31.0-1.00.7-0.60.61.21.2-1.21.0-1.0-1.0-1.11.11.0-1.0-1.01.0-0.8-0.90.9-0.9-0.80.9-0.90.8-0.8
Total zone transitions, NPP test1.72.43.2-1.71.5-1.51.0-1.0-1.8-1.81.8-1.51.51.61.6-1.6-1.61.61.6-1.61.51.5-1.61.61.5-1.41.4-1.61.2
Total locomotion distance, NPP test0.60.81.8-1.11.0-1.30.9-0.9-1.2-1.21.2-0.80.81.00.9-0.9-0.90.90.9-0.90.80.8-0.80.80.6-0.70.7-0.70.7
Locomotion velocity, NPP test0.60.81.7-1.11.0-1.30.8-0.8-1.2-1.21.2-0.80.81.10.9-0.9-0.90.90.9-0.90.80.8-0.80.80.6-0.70.7-0.70.6
Intraocular pressure0.00.00.3-0.1-0.0-0.50.1-0.2-0.00.2-0.20.2-0.20.0-0.30.30.0-0.1-0.00.1-0.1-0.10.2-0.2-0.10.3-0.30.3-0.3
Delta distance traveled before/after self-admin1.82.02.91.7-1.41.3-1.31.71.31.4-1.41.5-1.5-1.2-1.31.31.4-1.3-1.41.3-1.3-1.51.4-1.4-1.41.5-1.51.3-1.6
Delta ambulatory time before/after self-admin1.31.42.31.4-1.20.9-1.01.41.11.1-1.11.3-1.4-0.9-1.01.11.2-1.1-1.21.1-1.1-1.31.2-1.2-1.31.4-1.41.2-1.5
Parametrial fat weight3.36.47.82.6-2.62.0-2.02.02.52.7-2.72.6-2.5-2.8-2.72.72.5-2.8-2.52.8-2.6-2.42.6-2.6-2.62.3-2.32.7-1.8
Pavlov. Cond. lever latency1.11.43.7-1.31.5-1.71.9-1.9-1.1-1.11.1-1.11.01.31.2-1.2-1.11.01.0-1.01.20.9-1.21.21.2-0.70.7-0.70.7
Pavlov. Cond. magazine entry latency0.10.10.6-0.3-0.00.2-0.40.4-0.2-0.30.3-0.30.30.30.2-0.2-0.30.50.3-0.50.30.4-0.40.40.4-0.40.4-0.80.1
Pavlov. Cond. change in total contacts0.80.92.41.0-1.20.9-1.51.50.90.9-0.90.8-0.7-1.0-0.90.90.8-0.8-0.80.8-1.0-0.81.0-1.0-0.90.7-0.60.6-0.7
Pavlov. Cond. index score0.40.51.90.7-1.01.4-1.41.40.70.7-0.70.6-0.5-0.7-0.70.70.5-0.4-0.50.4-0.7-0.40.6-0.6-0.50.2-0.2-0.0-0.4
Pavlov. Cond. latency score0.50.62.00.8-1.01.4-1.41.40.70.7-0.70.6-0.6-0.7-0.80.80.6-0.5-0.60.5-0.7-0.50.7-0.7-0.60.3-0.30.1-0.4
Pavlov. Cond. lever contacts0.40.52.00.7-0.91.1-1.41.40.50.5-0.50.5-0.4-0.7-0.60.60.5-0.5-0.50.5-0.7-0.40.6-0.6-0.60.2-0.20.1-0.2
Pavlov. Cond. magazine entry number0.20.20.90.4-0.1-0.20.5-0.50.40.4-0.40.4-0.4-0.5-0.40.40.5-0.6-0.50.6-0.4-0.50.4-0.4-0.40.5-0.60.9-0.2
Pavlov. Cond. intertrial magazine entries0.40.42.1-0.90.6-1.40.2-0.2-0.7-0.60.6-0.50.51.00.6-0.6-0.60.80.6-0.80.70.5-0.70.70.7-0.30.2-0.8-0.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.90.7-1.01.2-1.41.40.60.6-0.60.5-0.5-0.6-0.70.70.5-0.4-0.50.4-0.6-0.40.5-0.5-0.50.2-0.2-0.0-0.4
Pavlov. Cond. response bias0.10.11.00.2-0.50.7-1.01.00.10.1-0.10.00.0-0.2-0.10.10.00.1-0.0-0.1-0.10.10.0-0.0-0.1-0.20.3-0.40.1
Pavlov. Cond. lever latency1.72.34.0-1.41.7-1.31.5-1.5-1.7-1.61.6-1.71.71.21.6-1.6-1.41.31.4-1.31.41.5-1.51.51.4-1.61.6-1.12.0
Pavlov. Cond. magazine entry latency2.02.33.01.5-1.61.2-1.51.51.61.6-1.61.6-1.6-1.4-1.51.51.5-1.4-1.51.4-1.5-1.51.5-1.5-1.51.6-1.61.4-1.7
Pavlov. Cond. change in total contacts2.33.24.01.6-1.81.3-1.71.71.91.8-1.81.9-1.9-1.5-1.81.81.7-1.7-1.71.7-2.0-1.81.9-1.9-1.91.9-1.91.6-2.0
Pavlov. Cond. index score2.22.93.51.6-1.81.4-1.61.61.81.8-1.81.8-1.8-1.5-1.71.71.6-1.6-1.61.6-1.8-1.61.8-1.8-1.81.7-1.71.4-1.9
Pavlov. Cond. latency score1.82.22.81.4-1.61.2-1.41.41.71.6-1.61.6-1.6-1.3-1.51.51.4-1.4-1.41.4-1.6-1.41.6-1.6-1.61.5-1.51.2-1.6
Pavlov. Cond. lever contacts2.93.95.72.0-2.11.7-2.02.02.02.0-2.02.1-2.2-1.6-2.02.01.9-1.8-1.91.8-2.0-2.02.0-2.0-2.02.1-2.11.7-2.4
Pavlov. Cond. magazine entry number0.81.01.6-0.91.1-0.61.1-1.0-1.1-1.11.1-1.11.10.91.0-1.1-1.00.91.0-0.91.01.0-1.01.01.1-1.01.0-0.71.3
Pavlov. Cond. intertrial magazine entries1.41.92.4-1.31.4-1.51.3-1.3-1.5-1.41.4-1.41.31.51.4-1.4-1.41.41.3-1.41.31.3-1.31.31.3-1.21.2-1.31.2
Pavlov. Cond. lever-magazine prob. diff.2.12.73.41.5-1.71.3-1.61.51.81.7-1.71.8-1.8-1.5-1.71.71.6-1.5-1.61.5-1.7-1.61.7-1.7-1.71.7-1.71.4-1.8
Pavlov. Cond. response bias2.43.34.91.8-1.91.5-1.81.71.81.8-1.82.0-2.0-1.5-1.81.81.7-1.6-1.71.6-1.8-1.81.8-1.8-1.81.9-1.91.5-2.2
Time in closed arm before self-admin0.00.10.3-0.1-0.1-0.6-0.10.5-0.2-0.20.2-0.1-0.00.40.3-0.3-0.10.30.1-0.20.1-0.1-0.00.00.00.1-0.2-0.1-0.4
Time in closed arm after self-admin0.00.00.20.3-0.00.4-0.40.40.1-0.20.2-0.20.2-0.10.3-0.30.00.0-0.0-0.00.1-0.00.0-0.0-0.4-0.10.10.10.1
Time in open arm before self-admin0.10.10.90.3-0.30.9-0.40.10.30.3-0.30.3-0.2-0.6-0.40.40.4-0.4-0.30.4-0.3-0.20.3-0.3-0.30.1-0.00.40.2
Time in open arm after self-admin2.62.83.91.3-1.81.3-1.31.51.71.9-1.91.9-1.9-1.6-2.01.91.7-1.7-1.71.7-1.6-1.71.5-1.5-1.51.8-1.81.7-1.7
Bone: periosteal estimation0.51.11.41.0-1.00.8-0.80.80.91.0-1.01.1-1.1-0.9-1.11.21.0-1.1-1.01.1-1.0-1.01.1-1.1-1.21.1-1.11.1-1.0
Bone: periosteal perimeter0.81.32.21.2-1.21.0-0.91.01.01.0-1.01.3-1.3-0.9-1.21.21.1-1.1-1.11.1-1.0-1.21.0-1.0-1.11.3-1.31.0-1.5
Bone: post-yield work1.21.62.31.5-1.41.3-1.51.51.11.1-1.11.2-1.2-1.4-1.21.21.3-1.3-1.31.3-1.3-1.31.2-1.2-1.31.2-1.11.3-1.1
Progressive ratio test 1 active lever presses2.12.23.7-1.91.3-1.41.1-0.9-1.5-1.51.5-1.41.41.81.3-1.3-1.71.81.6-1.81.41.6-1.31.31.5-1.41.4-1.80.9
Progressive ratio test 1 breakpoint2.82.95.0-2.21.5-1.71.4-1.2-1.7-1.61.6-1.61.62.01.5-1.5-1.92.01.9-2.01.61.8-1.61.61.7-1.71.6-2.11.1
Progressive ratio test 1 inactive lever presses0.50.51.3-1.20.5-0.70.5-0.1-0.6-0.70.7-0.60.60.90.5-0.5-0.91.00.8-1.00.70.8-0.60.60.9-0.80.8-1.00.4
Progressive ratio test 2 active lever presses0.10.11.5-0.1-0.4-0.1-1.11.20.10.0-0.00.1-0.10.3-0.00.0-0.00.30.0-0.3-0.0-0.10.0-0.0-0.10.2-0.2-0.4-0.6
Progressive ratio test 2 breakpoint0.10.11.2-0.2-0.4-0.2-1.01.1-0.1-0.10.1-0.0-0.00.30.0-0.0-0.10.40.1-0.40.10.0-0.00.00.10.0-0.1-0.4-0.5
Progressive ratio test 2 inactive lever presses0.20.20.70.2-0.60.3-0.80.90.80.4-0.40.5-0.5-0.0-0.50.50.3-0.1-0.30.1-0.3-0.40.4-0.4-0.40.5-0.50.1-0.8
Incentive Sensitization - Responses0.50.52.00.6-0.90.2-1.41.40.80.7-0.70.6-0.7-0.4-0.50.50.6-0.4-0.70.4-0.5-0.70.5-0.5-0.60.7-0.70.4-0.9
Incentive Sensitization - Breakpoint0.60.62.20.7-0.90.2-1.51.50.80.8-0.80.7-0.7-0.5-0.60.60.7-0.5-0.70.5-0.6-0.80.6-0.6-0.60.8-0.80.5-0.9
Sum of active levers in priming session hrs 5-62.82.75.6-1.61.7-1.21.6-1.6-1.8-1.71.7-1.81.81.11.6-1.6-1.61.31.6-1.31.61.8-1.61.61.5-2.02.0-1.42.4
Progressive ratio0.30.30.5-0.70.5-0.50.5-0.3-0.6-0.60.6-0.50.50.70.5-0.5-0.50.60.5-0.60.70.4-0.60.60.5-0.30.3-0.60.1
Food seeking constrained by brief footshock4.55.57.7-2.82.4-2.32.8-2.5-2.1-2.22.2-2.22.22.42.2-2.1-2.42.42.4-2.42.22.4-2.42.42.3-2.22.2-2.42.0
Seeking ratio, punishment vs. effort0.81.01.5-1.01.1-1.01.2-1.2-0.8-0.80.8-1.01.00.90.9-0.9-1.01.01.0-1.00.91.1-1.01.01.0-1.11.1-1.01.1
Retroperitoneal fat weight0.20.60.9-0.90.7-0.40.6-0.5-0.7-0.70.7-0.80.80.80.8-0.8-0.80.90.8-0.90.80.8-0.80.80.7-0.80.8-0.70.7
Reaction time number correct0.10.10.5-0.40.1-0.7-0.0-0.00.00.1-0.10.2-0.20.2-0.10.10.1-0.1-0.10.1-0.4-0.30.4-0.4-0.60.5-0.50.4-0.6
Reaction time mean minus median1.01.32.11.3-1.31.5-1.41.20.91.1-1.11.3-1.3-1.0-1.21.21.1-0.9-1.11.0-1.0-1.11.0-1.0-1.01.1-1.10.8-1.4
Reaction time mean minus median AUC0.20.30.70.6-0.60.7-0.50.40.40.6-0.60.7-0.7-0.4-0.70.70.5-0.4-0.50.4-0.5-0.50.4-0.4-0.50.6-0.60.3-0.8
Reaction time num false alarms0.40.50.80.6-0.60.7-0.40.60.80.7-0.70.7-0.8-0.5-0.60.60.7-0.6-0.70.6-0.7-0.70.8-0.8-0.80.9-0.90.6-0.9
Reaction time num false alarms AUC1.01.41.91.2-1.11.1-0.91.11.21.2-1.21.3-1.3-0.9-1.11.11.2-1.1-1.21.1-1.2-1.21.3-1.3-1.31.4-1.41.0-1.3
Reaction time trials correct on left0.10.10.5-0.40.1-0.7-0.0-0.00.00.1-0.10.2-0.20.2-0.10.10.1-0.1-0.10.1-0.4-0.30.4-0.4-0.60.5-0.50.4-0.6
Reaction time trials on left0.10.10.4-0.3-0.0-0.6-0.10.10.10.2-0.20.3-0.30.1-0.20.20.2-0.1-0.20.1-0.4-0.30.4-0.4-0.60.5-0.60.5-0.6
Reaction time mean0.71.01.61.3-1.21.0-1.21.00.80.9-0.91.0-1.0-1.1-1.01.01.0-1.0-1.01.0-1.0-1.00.9-0.9-0.80.9-0.90.8-1.0
Reaction time mean AUC0.30.40.70.8-0.80.7-0.80.70.50.6-0.60.7-0.6-0.8-0.70.70.6-0.7-0.60.7-0.6-0.60.6-0.6-0.50.5-0.50.5-0.5
Median of all reaction times0.50.71.11.1-0.90.7-0.90.70.60.7-0.70.8-0.8-0.9-0.80.80.8-0.9-0.80.9-0.8-0.80.8-0.8-0.70.8-0.80.8-0.8
Reaction time omissions0.60.82.11.1-1.21.4-1.31.21.11.0-1.00.9-0.8-0.9-0.90.90.9-0.7-0.80.7-0.7-0.80.6-0.6-0.70.7-0.60.6-0.7
Reaction time false alarm rate1.11.52.31.5-1.31.5-1.01.21.31.3-1.31.3-1.3-1.1-1.21.21.3-1.2-1.31.2-1.2-1.21.2-1.2-1.21.2-1.31.0-1.2
Reaction time premature initiation rate0.20.30.6-0.20.50.00.1-0.1-0.7-0.70.7-0.60.60.40.6-0.6-0.50.50.5-0.50.50.5-0.60.60.6-0.60.7-0.50.8
Reaction time premature initiations0.30.40.7-0.60.7-0.40.3-0.3-0.8-0.80.8-0.70.70.60.8-0.8-0.60.60.6-0.60.50.6-0.60.60.4-0.60.6-0.40.7
Std. dev. reaction times2.43.34.32.0-2.12.1-1.91.81.81.8-1.81.9-1.9-1.9-2.01.91.8-1.8-1.81.8-1.8-1.81.7-1.7-1.71.7-1.61.6-1.7
Reaction time trials completed0.10.10.4-0.3-0.0-0.6-0.10.10.10.2-0.20.3-0.30.1-0.20.20.2-0.1-0.20.1-0.4-0.30.4-0.4-0.60.5-0.60.5-0.6
Reaction time trials AUC0.10.10.4-0.3-0.0-0.5-0.10.10.10.2-0.20.3-0.30.1-0.20.20.2-0.1-0.20.1-0.4-0.30.4-0.4-0.60.6-0.60.5-0.7
Run reversals in cocaine runway, females0.00.00.2-0.10.10.30.4-0.40.20.2-0.10.1-0.1-0.3-0.10.10.0-0.1-0.00.1-0.30.10.2-0.2-0.1-0.20.20.10.4
Run reversals in cocaine runway, males0.70.61.00.7-0.91.0-0.40.60.90.9-0.90.8-0.8-0.9-0.90.90.8-0.8-0.80.8-0.9-0.70.8-0.8-0.80.7-0.70.8-0.7
Latency to leave start box in cocaine runway0.50.61.1-1.10.9-0.81.0-0.9-0.7-0.70.7-0.80.80.80.7-0.7-0.80.70.8-0.70.70.8-0.60.60.6-0.70.7-0.60.7
Latency to leave start box in cocaine runway, F0.10.10.1-0.20.2-0.20.2-0.1-0.4-0.30.3-0.20.20.40.2-0.2-0.30.30.3-0.30.20.2-0.20.20.2-0.20.2-0.2-0.0
Latency to leave start box in cocaine runway, M0.80.81.8-1.31.2-0.81.2-1.2-0.7-0.60.6-1.01.00.70.9-0.9-0.90.70.9-0.70.80.9-0.70.70.6-1.01.0-0.61.2
Std. dev. time between licks in bursts0.10.10.6-0.20.3-0.20.6-0.6-0.2-0.20.2-0.20.2-0.00.1-0.1-0.2-0.00.2-0.00.10.3-0.10.10.2-0.40.40.20.8
Total sessions with >9 infusions0.70.81.9-1.40.8-0.61.1-0.8-0.9-1.01.0-0.70.81.20.6-0.6-1.01.11.0-1.10.80.9-0.70.70.7-0.70.7-1.20.4
Short access day 1 total inactive lever presses0.50.51.90.8-1.01.4-1.01.00.90.7-0.70.8-0.7-0.8-0.80.80.6-0.6-0.60.6-0.6-0.50.5-0.5-0.20.4-0.40.4-0.4
Short access day 10 total inactive lever presses1.11.32.31.1-0.90.8-0.40.21.41.3-1.31.1-1.1-1.5-1.21.21.2-1.5-1.21.5-1.1-1.01.2-1.2-1.00.9-0.91.5-0.3
Short access day 1 total infusions0.10.10.4-0.2-0.20.10.5-0.20.30.2-0.20.4-0.40.2-0.30.30.1-0.0-0.10.0-0.2-0.20.2-0.2-0.00.4-0.5-0.0-0.6
Short access day 10 total infusions0.10.11.2-0.0-0.50.8-0.81.10.10.0-0.00.1-0.0-0.0-0.20.20.00.1-0.0-0.1-0.1-0.00.1-0.1-0.10.0-0.0-0.1-0.4
Short access total infusions0.10.21.00.1-0.50.4-0.20.50.30.3-0.30.5-0.50.1-0.50.50.2-0.1-0.30.1-0.3-0.40.4-0.4-0.30.6-0.60.0-1.0
Short access day 1 locomotion0.91.01.90.8-1.11.1-0.80.81.11.1-1.11.1-1.1-0.6-1.11.10.8-0.7-0.80.7-1.0-0.91.1-1.1-1.01.0-1.10.6-1.4
Short access day 10 total locomotion0.40.42.20.9-0.91.2-1.31.50.50.5-0.50.4-0.3-0.7-0.40.40.5-0.4-0.50.4-0.3-0.40.4-0.4-0.20.2-0.20.1-0.3
Short access total locomotion0.00.10.3-0.1-0.20.5-0.20.40.00.1-0.10.00.00.3-0.00.0-0.10.30.1-0.30.10.0-0.00.00.20.1-0.1-0.4-0.5
One hour access (0.3 mA shock)0.50.53.80.6-0.90.7-2.01.90.50.3-0.30.4-0.4-0.4-0.30.30.6-0.3-0.60.3-0.3-0.70.3-0.3-0.40.6-0.60.3-0.9
Compulsive drug intake4.74.87.32.7-2.12.3-2.32.12.12.1-2.12.1-2.1-2.3-2.02.12.4-2.3-2.42.3-2.1-2.32.1-2.1-2.02.2-2.22.2-1.9
One hour access (shock baseline)1.31.52.3-1.50.9-1.20.2-0.1-1.2-1.31.3-1.21.21.41.2-1.2-1.31.51.3-1.51.31.3-1.31.31.2-1.21.2-1.40.7
Social response proportion0.20.20.70.4-0.6-0.1-0.70.80.20.3-0.30.4-0.4-0.3-0.30.30.4-0.4-0.50.4-0.4-0.60.5-0.5-0.50.7-0.70.5-0.8
Social responses0.30.40.8-0.40.20.1-0.20.3-0.5-0.70.7-0.60.60.60.7-0.7-0.60.80.6-0.80.80.7-0.80.80.9-0.70.8-0.90.4
Social time0.10.10.30.1-0.50.5-0.50.50.20.2-0.20.2-0.2-0.1-0.30.30.10.1-0.1-0.1-0.3-0.10.2-0.2-0.10.1-0.1-0.4-0.4
Soleus weight0.10.30.5-0.50.5-0.50.5-0.5-0.7-0.70.7-0.70.60.60.7-0.7-0.50.60.5-0.60.60.5-0.60.60.5-0.50.5-0.50.4
Bone: stiffness0.10.20.5-0.50.5-0.20.5-0.5-0.5-0.50.5-0.40.40.50.4-0.4-0.40.40.4-0.40.70.4-0.70.70.6-0.40.4-0.40.3
Tibialis anterior weight8.027.534.85.9-5.55.4-4.84.85.45.3-5.35.3-5.3-5.5-5.25.25.3-5.4-5.35.4-5.3-5.25.3-5.3-5.34.9-4.95.3-4.5
Time to tail flick, vehicle, before self-admin2.22.32.81.5-1.51.4-1.61.31.71.5-1.51.5-1.4-1.6-1.51.51.5-1.6-1.51.6-1.6-1.51.6-1.6-1.51.4-1.41.4-1.2
Time to tail flick, vehicle, after self-admin1.31.32.31.0-1.10.6-0.70.91.51.3-1.31.3-1.3-1.0-1.11.11.1-1.2-1.11.2-1.2-1.21.2-1.2-1.11.3-1.31.2-1.2
Time to tail flick, test, before self-admin0.10.10.20.3-0.10.1-0.2-0.10.40.3-0.30.3-0.4-0.2-0.10.10.3-0.3-0.30.3-0.2-0.30.2-0.2-0.30.3-0.30.2-0.3
Time to tail flick, test, after self-admin0.10.10.30.00.0-0.50.4-0.50.50.4-0.40.3-0.4-0.1-0.20.20.1-0.3-0.10.3-0.3-0.10.4-0.4-0.40.3-0.30.3-0.3
Delta time to tail flick, vehicle, before/after SA1.01.01.8-1.11.1-1.31.4-1.2-0.9-0.90.9-0.90.81.11.0-1.0-1.00.91.0-0.91.00.9-1.01.00.8-0.80.8-0.70.8
Delta time to tail flick, test, before/after SA0.50.40.70.6-0.60.1-0.40.30.70.7-0.70.7-0.7-0.4-0.80.70.6-0.6-0.60.6-0.6-0.60.7-0.7-0.70.7-0.80.8-0.7
Tibia length2.56.99.4-2.82.8-2.33.1-3.0-2.4-2.62.6-2.62.62.62.6-2.6-2.72.62.7-2.62.62.7-2.52.52.6-2.62.6-2.52.4
Ambulatory time before self-admin0.10.10.7-0.40.30.00.6-0.7-0.2-0.40.4-0.30.5-0.10.1-0.1-0.30.10.3-0.10.20.4-0.30.30.2-0.50.5-0.10.8
Ambulatory time after self-admin1.21.32.11.3-1.31.1-1.01.51.11.0-1.01.0-1.0-1.2-1.01.01.2-1.2-1.21.2-1.0-1.21.0-1.0-1.31.1-1.01.3-0.9
Bone: tissue strength0.70.71.70.9-1.00.8-1.31.30.70.6-0.60.8-0.8-0.8-0.70.70.9-0.8-0.90.8-0.5-1.00.6-0.6-0.60.9-0.90.6-1.2
Total heroin consumption1.71.92.5-1.61.3-1.21.2-1.0-1.6-1.41.4-1.51.51.21.5-1.5-1.41.31.4-1.31.51.3-1.51.51.4-1.41.4-1.31.4
Bone: trabecular number0.00.00.1-0.30.2-0.10.2-0.2-0.00.1-0.10.1-0.20.20.0-0.0-0.10.10.1-0.10.10.1-0.10.10.3-0.0-0.0-0.2-0.0
Bone: trabecular spacing0.10.10.3-0.40.1-0.6-0.20.2-0.3-0.30.3-0.40.40.00.4-0.4-0.20.20.2-0.20.20.3-0.20.20.1-0.40.5-0.10.5
Bone: trabecular thickness0.10.10.5-0.50.4-0.40.7-0.7-0.3-0.20.2-0.10.00.60.1-0.1-0.40.40.4-0.40.40.3-0.40.40.5-0.10.0-0.3-0.1
Bone: trabecular tissue density16.122.726.2-5.14.9-4.94.6-4.6-4.7-4.84.8-4.74.65.14.8-4.8-4.85.04.8-4.95.04.6-5.05.04.9-4.44.3-4.73.7
Water consumed over 24 hours0.10.10.50.6-0.50.3-0.60.70.20.2-0.20.00.0-0.7-0.20.20.3-0.5-0.30.5-0.1-0.20.1-0.1-0.1-0.10.10.30.6
Number of responses in last shaping day0.20.22.70.2-0.41.6-0.40.50.00.3-0.30.1-0.0-0.6-0.30.30.1-0.2-0.10.2-0.30.00.6-0.6-0.1-0.30.30.30.4