Hub : Genes

LOC102552452

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC102552452 0.51 0.15 7.1e-07 0.25 0.1 0.32 0.2 1.2e-06 2.3e-03 2.3e-08 1.3e-05
2 Liver gene expression LOC102552452 0.59 0.12 0.0e+00 0.35 0.36 0.35 0.37 1.3e-40 6.8e-42 1.5e-40 1.4e-42
3 Adipose alternative TSS XR_005491757.1 0.03 0.02 3.6e-03 0.01 0.01 0.01 0 2.8e-02 2.0e-02 1.7e-02 7.2e-02
4 Adipose gene expression LOC102552452 0.21 0.11 1.8e-11 0.1 0.09 0.1 0.09 5.9e-11 4.1e-10 6.3e-11 7.8e-10
5 BLA alternative TSS XR_005491761.1 0.06 0.05 3.3e-03 0.05 0.05 0.04 0.04 1.4e-03 1.6e-03 1.8e-03 1.9e-03
6 PL gene expression LOC102552452 0.3 0.13 0.0e+00 0.25 0.23 0.23 0.23 3.8e-27 7.3e-25 5.9e-25 2.9e-25
7 Liver alternative TSS XR_005491759.1 0.04 0.03 7.4e-03 0.01 0.01 0 0.01 2.1e-02 2.0e-02 1.5e-01 1.7e-02
8 Brain gene expression LOC102552452 0.19 0.09 0.0e+00 0.21 0.16 0.2 0.09 3.3e-19 1.1e-14 7.9e-19 4.7e-09
9 NAcc gene expression LOC102552452 0.15 0.08 1.8e-15 0.15 0.14 0.15 0.15 7.1e-17 3.8e-16 3.5e-17 1.9e-17
10 BLA gene expression LOC102552452 0.33 0.14 1.6e-12 0.24 0.24 0.23 0.25 2.5e-13 5.1e-13 1.6e-12 1.3e-13
11 pVTA gene expression LOC102552452 0.22 0.17 1.2e-04 0.06 0.07 0.06 0.08 1.9e-03 8.3e-04 1.3e-03 1.8e-04
12 OFC gene expression LOC102552452 0.2 0.11 2.1e-04 0.11 0.13 0.09 0.12 1.3e-03 6.4e-04 3.2e-03 1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density6.110.114.5-3.83.4-3.2-3.43.3-3.3-3.3-3.33.02.92.62.3
Area under the delay curve0.10.10.40.1-0.2-0.00.10.3-0.1-0.3-0.40.30.60.50.6
BMI with tail3.210.312.5-3.53.1-2.7-3.33.4-3.5-3.3-3.43.23.33.12.4
BMI without tail2.96.19.8-3.12.6-2.4-2.52.7-2.7-2.7-2.72.22.21.91.4
Body weight10.544.173.9-8.67.3-6.7-7.07.2-7.1-7.1-7.15.85.94.93.8
Weight adjusted by age0.10.10.4-0.40.6-0.6-0.5-0.1-0.5-0.00.10.3-0.30.3-0.2
Bone surface6.811.917.3-4.23.7-3.4-3.73.6-3.6-3.6-3.73.23.22.92.4
Bone volume6.410.813.7-3.73.4-3.2-3.53.4-3.4-3.4-3.53.23.23.02.5
Breakpoint value in progressive ratio session2.62.83.6-1.31.8-1.7-1.91.5-1.8-1.6-1.51.81.61.81.8
Number of licking bursts4.85.69.11.5-2.02.02.4-2.22.32.22.3-2.7-2.6-3.0-2.9
Context. condit. distance diff. score9.211.112.6-3.63.5-3.3-3.43.4-3.5-3.5-3.43.23.32.92.9
Locomotion velocity, session 10.00.00.20.4-0.1-0.00.1-0.1-0.20.30.30.1-0.10.20.2
Locomotion distance, session 10.50.61.41.2-0.90.70.9-0.60.80.80.9-0.5-0.6-0.4-0.4
Locomotion velocity, session 20.80.91.10.9-1.00.81.0-1.00.81.11.0-0.9-1.0-0.9-0.9
Locomotion distance, session 21.21.72.51.6-1.31.11.4-1.21.31.51.5-1.2-1.4-1.2-0.9
Locomotion velocity, session 31.71.92.4-1.31.4-1.4-1.41.3-1.5-1.3-1.41.41.41.51.3
Locomotion distance, session 30.10.10.1-0.20.3-0.3-0.20.2-0.2-0.2-0.20.30.20.20.3
Stereotopy head waving bouts, day 30.91.01.9-1.41.3-1.4-1.20.8-1.3-0.8-0.90.90.50.70.5
Stereotopy head waving duration, day 30.00.00.10.0-0.0-0.0-0.1-0.2-0.10.10.10.0-0.10.1-0.1
Locomotion velocity, session 70.10.10.30.5-0.50.60.4-0.20.30.30.4-0.3-0.2-0.1-0.2
Locomotion distance, session 70.00.00.2-0.00.2-0.1-0.10.4-0.1-0.3-0.10.10.30.10.3
Stereotopy head waving bouts, day 70.10.10.30.5-0.20.00.2-0.5-0.10.40.3-0.1-0.20.10.2
Stereotopy head waving duration, day 70.40.51.01.0-0.70.50.6-1.00.40.90.8-0.6-0.8-0.3-0.4
Locomotion velocity, session 80.00.10.2-0.40.2-0.2-0.10.3-0.2-0.3-0.30.10.30.10.1
Locomotion distance, session 81.92.83.7-1.91.7-1.7-1.61.9-1.7-1.8-1.81.51.71.41.3
Degree of sensitization distance0.90.91.41.1-1.11.21.0-0.71.10.90.9-1.0-0.8-0.9-0.8
Degree of sensitization stereotypy0.00.00.10.3-0.1-0.00.1-0.2-0.10.10.1-0.00.00.20.3
Conditioned locomotion0.81.01.4-0.90.8-0.8-0.91.2-0.9-1.0-1.11.01.11.01.0
Cocaine response after cond. corrected0.10.10.2-0.2-0.20.4-0.10.30.0-0.2-0.20.10.40.3-0.2
Cocaine response after cond. not corrected1.21.32.0-1.00.8-0.6-1.21.3-1.1-1.2-1.11.21.41.41.0
Cocaine response before conditioning3.94.76.3-1.62.3-2.3-2.32.0-2.3-2.0-2.02.32.02.32.5
Saline control response0.30.31.3-0.20.4-0.40.1-0.50.10.60.5-0.5-1.1-0.9-0.6
Bone: connectivity density6.510.216.6-4.13.6-3.3-3.43.4-3.2-3.4-3.42.92.82.42.1
Bone: cortical apparent density0.00.00.20.2-0.40.50.2-0.10.10.20.1-0.00.00.1-0.1
Bone: cortical area3.75.66.8-2.62.5-2.5-2.52.4-2.5-2.4-2.42.32.22.11.9
Bone: cortical porosity0.10.10.30.3-0.1-0.10.1-0.40.10.40.5-0.2-0.5-0.2-0.3
Bone: cortical porosity0.10.10.40.6-0.1-0.10.2-0.50.20.50.6-0.1-0.5-0.10.0
Bone: cortical thickness2.64.36.1-2.52.1-2.0-2.12.2-2.1-2.2-2.32.02.11.71.5
Bone: cortical thickness0.40.50.9-1.00.9-1.0-0.70.6-0.7-0.6-0.70.40.40.30.3
Bone: cortical tissue density0.10.10.40.3-0.50.60.3-0.20.20.30.2-0.1-0.10.0-0.2
Condit. Reinf. active minus inactive responses0.10.10.20.3-0.10.1-0.20.1-0.1-0.0-0.00.30.30.50.4
Condit. Reinf. active-inactive response ratio0.30.30.9-0.10.4-0.4-0.70.4-0.6-0.4-0.40.80.60.90.7
Condit. Reinf. active responses0.10.10.50.20.2-0.2-0.30.3-0.2-0.2-0.10.40.30.50.7
Condit. Reinf. inactive responses0.10.10.40.6-0.2-0.00.3-0.10.30.20.3-0.2-0.2-0.10.3
Incentive salience index mean0.20.30.90.00.3-0.4-0.50.5-0.5-0.4-0.40.70.60.80.9
Condit. Reinf. lever presses0.60.81.8-0.40.8-0.9-0.80.9-0.8-0.9-0.81.01.01.11.3
Condit. Reinf. active minus inactive responses0.40.51.1-1.00.9-0.8-0.70.8-0.7-0.8-0.80.40.70.20.4
Condit. Reinf. active-inactive response ratio0.00.10.3-0.0-0.00.10.2-0.20.30.10.1-0.3-0.2-0.5-0.2
Condit. Reinf. active responses1.92.63.4-1.81.8-1.7-1.71.6-1.6-1.7-1.71.41.51.21.5
Condit. Reinf. inactive responses1.72.12.6-1.41.6-1.5-1.61.3-1.6-1.3-1.41.31.21.41.4
Condit. Reinf. lever presses2.53.43.7-1.71.9-1.9-1.91.7-1.9-1.8-1.81.81.81.81.9
Condit. Reinf. lever reinforcers received1.21.72.3-1.41.5-1.4-1.41.2-1.3-1.3-1.41.11.21.01.3
Conditioned reinforcement - actives1.01.02.9-1.71.1-1.3-0.71.1-0.9-1.1-1.20.30.6-0.20.1
Conditioned reinforcement - inactives0.40.41.20.1-0.50.40.8-0.30.70.40.3-0.9-0.6-1.1-0.9
Conditioned locomotion2.02.43.9-2.01.7-1.9-1.51.9-1.3-1.7-1.71.11.30.61.0
Patch foraging indifference point 0 sec0.00.00.1-0.30.2-0.10.00.1-0.2-0.2-0.2-0.10.1-0.10.1
Patch foraging indifference point AUC0.20.20.7-0.80.4-0.2-0.20.5-0.2-0.5-0.7-0.00.4-0.20.1
Delay disc. indifference point, 0s delay0.20.20.4-0.40.0-0.1-0.30.5-0.4-0.5-0.50.40.60.70.2
Delay disc. indifference point, 16s delay0.10.10.20.0-0.40.30.40.30.4-0.2-0.3-0.10.4-0.10.1
Delay disc. indifference point, 2s delay0.70.82.50.10.3-0.4-0.80.5-0.9-0.6-0.61.21.11.61.5
Delay disc. indifference point, 24s delay0.60.61.20.7-1.00.91.1-0.51.00.50.4-0.9-0.3-0.8-0.5
Delay disc. indifference point, 4s delay0.40.51.2-0.10.2-0.4-0.50.6-0.6-0.6-0.70.70.91.01.1
Delay disc. indifference point, 8s delay0.00.00.20.2-0.2-0.00.20.1-0.1-0.1-0.10.20.30.30.4
Indifference point function ln k0.30.51.40.8-0.10.10.3-1.10.30.91.1-0.3-1.2-0.5-0.5
Indifference point function log k0.30.51.40.8-0.10.10.3-1.10.30.91.1-0.3-1.2-0.5-0.5
Patch foraging total patch changes 0 sec0.00.00.1-0.20.1-0.20.1-0.0-0.1-0.1-0.2-0.20.0-0.20.1
Patch foraging total patch changes 12 sec0.20.30.5-0.70.6-0.3-0.50.5-0.6-0.5-0.70.50.50.50.4
Patch foraging total patch changes 18 sec0.10.20.5-0.1-0.30.40.4-0.30.40.20.1-0.6-0.3-0.7-0.4
Patch foraging total patch changes 24 sec0.10.20.4-0.40.3-0.5-0.10.5-0.2-0.4-0.6-0.00.5-0.00.6
Patch foraging total patch changes 6 sec0.20.30.5-0.70.6-0.5-0.40.5-0.6-0.6-0.60.30.40.30.4
Patch foraging time to switch 0 sec0.40.61.81.1-1.31.20.8-0.50.60.60.7-0.4-0.00.2-0.4
Patch foraging water rate 0 sec0.71.13.0-1.41.7-1.6-1.10.8-1.0-0.9-0.90.60.20.10.5
Patch foraging water rate 12 sec0.10.10.7-0.20.7-0.8-0.30.2-0.3-0.1-0.10.2-0.2-0.10.4
Patch foraging water rate 18 sec0.10.10.40.40.5-0.7-0.1-0.2-0.10.20.30.2-0.40.10.5
Patch foraging water rate 24 sec0.50.62.1-0.81.4-1.4-1.00.4-0.9-0.4-0.40.7-0.10.30.5
Patch foraging water rate 6 sec1.21.82.9-1.11.7-1.7-1.51.3-1.3-1.2-1.11.31.01.01.4
Seeking ratio, delayed vs. immediate footshock5.46.28.52.4-2.72.92.7-2.22.82.42.3-2.6-2.0-2.4-2.2
Distance traveled before self-admin0.10.10.40.7-0.30.30.2-0.50.10.40.50.0-0.20.10.3
Distance traveled after self-admin0.10.10.3-0.40.1-0.20.00.5-0.2-0.5-0.50.00.50.00.4
Extensor digitorum longus weight5.521.530.2-5.55.1-5.1-4.74.9-4.8-4.9-4.94.14.23.53.5
Bone: elastic displacement0.10.10.3-0.50.4-0.5-0.30.4-0.4-0.3-0.30.20.20.1-0.0
Bone: elastic work2.63.45.7-2.42.1-2.2-1.82.0-1.9-1.9-1.91.51.51.21.1
Bone: endosteal estimation0.10.30.8-0.90.9-0.9-0.50.4-0.6-0.4-0.40.1-0.0-0.0-0.0
Bone: endosteal perimeter1.53.14.6-1.82.1-2.1-2.01.7-1.9-1.6-1.61.71.31.51.5
Epididymis fat weight1.94.55.4-1.82.0-1.9-2.12.3-2.0-2.2-2.22.22.32.12.3
Delta time in closed arm before/after self-admin0.00.00.0-0.1-0.0-0.1-0.1-0.0-0.00.0-0.1-0.1-0.2-0.10.1
Delta time in open arm before/after self-admin0.40.31.51.2-0.50.40.5-0.70.40.70.9-0.0-0.20.30.1
Diff in mean of infusions in LGA sessions0.91.01.6-0.61.2-1.1-1.20.7-1.3-0.8-0.71.20.71.01.2
Delay discount exponential model param0.20.20.6-0.10.10.10.1-0.40.20.40.5-0.4-0.7-0.6-0.8
Extinction: sum of active levers before priming0.20.20.60.0-0.00.1-0.20.5-0.1-0.4-0.50.30.80.60.8
Active lever presses in extinction session 61.11.11.5-1.10.9-1.0-0.91.2-0.9-1.2-1.20.81.20.80.9
Bone: final force0.81.23.1-1.81.4-1.3-1.11.1-1.1-1.1-1.20.80.70.40.3
Bone: final moment0.50.72.1-1.51.1-1.1-0.90.8-0.9-0.9-0.90.50.50.20.1
Food consumed during 24 hour testing period0.60.71.40.7-0.50.50.6-0.90.70.90.9-0.7-1.2-0.9-0.9
Glucose0.20.20.60.5-0.80.80.6-0.30.50.30.4-0.4-0.2-0.2-0.4
Heart weight0.91.33.00.8-0.80.71.4-1.01.41.00.9-1.4-1.3-1.7-0.8
Delay discount hyperbolic model param0.20.20.6-0.20.20.10.0-0.30.20.30.4-0.4-0.6-0.7-0.8
Intermittent access intake day 1-15 change0.10.10.6-0.60.0-0.20.20.10.0-0.1-0.2-0.5-0.2-0.7-0.6
Intermittent access intake escalation0.20.20.7-0.80.4-0.6-0.20.4-0.3-0.4-0.5-0.10.1-0.4-0.2
Intermittent access intake escalation 20.10.10.2-0.1-0.1-0.10.3-0.10.10.00.0-0.5-0.2-0.5-0.2
Intermitt. access day 1 inactive lever presses0.60.71.80.3-0.60.71.0-0.40.90.60.5-1.2-0.7-1.4-0.9
Intermitt. access day 15 inactive lever presses0.20.20.50.5-0.60.70.4-0.50.20.50.5-0.4-0.4-0.0-0.7
Intermitt. access escalation Index0.10.10.30.10.2-0.4-0.10.1-0.1-0.1-0.10.20.10.10.6
Intermittent access day 1 total infusions0.10.10.20.5-0.3-0.20.4-0.10.30.1-0.1-0.10.1-0.10.4
Intermittent access day 15 total infusions0.10.10.5-0.30.2-0.70.10.3-0.1-0.3-0.5-0.10.1-0.20.3
Intermittent access terminal intake (last 3 days)0.00.10.20.2-0.3-0.10.4-0.10.20.1-0.1-0.3-0.1-0.30.0
Intermittent access total infusions0.00.10.20.1-0.0-0.40.10.2-0.1-0.1-0.30.00.30.20.5
Intermittent access day 1 locomotion0.40.41.80.30.3-0.7-0.30.4-0.4-0.3-0.40.90.61.01.3
Intermittent access day 15 total locomotion0.70.82.1-0.50.8-1.5-0.50.8-0.7-0.9-0.90.70.80.61.3
Intermittent access total locomotion0.30.31.50.20.3-0.8-0.10.4-0.2-0.4-0.40.60.50.61.2
Intermittent access standard deviation0.10.10.4-0.1-0.20.20.2-0.20.00.10.2-0.4-0.3-0.3-0.6
Left kidney weight4.011.223.5-4.84.1-3.8-3.63.5-3.3-3.6-3.62.72.41.71.6
Right kidney weight3.28.918.8-4.33.7-3.4-3.33.1-3.1-3.1-3.12.42.21.61.2
Cocaine induced anxiety1.61.93.2-0.81.1-1.2-1.41.3-1.4-1.3-1.21.61.51.61.8
Post-drug Anxiety0.20.20.91.0-0.60.50.1-0.30.10.30.10.30.30.70.7
Baseline Anxiety2.12.24.01.9-1.92.01.6-1.51.61.61.4-1.2-1.0-0.7-1.1
Tail length4.212.823.4-4.84.3-4.1-3.83.7-3.7-3.8-3.73.02.72.11.8
Length with tail8.731.860.3-7.86.6-6.2-5.96.1-5.8-6.1-6.04.54.63.42.9
Length without tail8.318.329.4-5.44.7-4.3-4.54.6-4.4-4.5-4.63.83.93.22.7
Times rat made contact with spout0.20.31.00.20.1-0.20.1-0.70.10.70.7-0.3-1.0-0.5-0.6
Lifetime Intake0.00.00.10.3-0.30.00.3-0.10.10.1-0.1-0.10.10.00.2
Liver weight, left0.10.20.8-0.90.5-0.3-0.20.4-0.3-0.4-0.50.10.1-0.2-0.2
Liver weight, right3.15.28.7-3.02.6-2.4-2.32.4-2.3-2.4-2.42.02.01.61.6
Locomotor activity1.01.63.0-1.61.7-1.7-1.31.2-1.5-1.2-1.11.00.70.60.8
Locomotor testing distance0.20.30.9-0.70.9-0.8-0.60.4-0.8-0.4-0.30.3-0.10.10.1
Locomotor testing rearing0.10.10.40.30.3-0.1-0.3-0.4-0.40.50.60.3-0.60.2-0.0
Locomotion in novel chamber0.40.51.30.4-0.30.00.7-0.70.60.70.6-1.0-0.8-1.1-0.5
Locomotion in novel chamber post-restriction0.60.72.3-1.11.3-1.5-0.80.7-0.9-0.7-0.80.50.30.10.6
Fecal boli incidents, locomotor time 11.21.32.5-1.41.6-1.4-1.41.2-1.1-1.1-1.10.90.90.50.8
Change in fecal boli incidents, locomotor task1.11.11.61.1-1.31.21.1-1.01.01.01.0-0.9-0.9-0.7-1.0
Time >=10cm from walls, locomotor time 10.40.41.10.10.2-0.4-0.60.4-0.8-0.4-0.40.80.71.01.0
Bouts of movement, locomotor time 10.50.61.2-1.10.8-1.0-0.51.1-0.8-1.0-0.80.20.6-0.00.3
Total resting periods, locomotor time 10.60.71.6-1.10.9-1.1-0.71.3-0.8-1.1-0.80.30.70.10.4
Rest time, locomotor task time 11.41.62.4-1.31.5-1.3-1.51.4-1.4-1.3-0.91.21.01.00.8
Distance moved, locomotor task time 10.70.81.41.0-0.90.91.0-1.21.01.10.8-0.7-0.9-0.7-0.5
Vertical activity count, locomotor time 10.10.20.40.0-0.40.40.6-0.30.60.3-0.1-0.5-0.2-0.5-0.2
Time >=10cm from walls, locomotor time 23.33.55.1-1.71.7-1.6-2.01.8-2.3-1.8-1.72.01.82.11.7
Bouts of movement, locomotor time 22.32.52.9-1.71.7-1.7-1.71.7-1.7-1.6-1.51.51.41.31.3
Total resting periods, locomotor time 22.02.22.8-1.61.6-1.6-1.61.5-1.7-1.5-1.51.41.31.21.2
Rest time, locomotor task time 20.40.40.9-0.10.7-0.7-0.90.3-0.8-0.3-0.10.90.40.90.7
Distance moved, locomotor task time 21.61.92.50.9-1.31.31.5-1.31.51.31.1-1.6-1.4-1.6-1.5
Vertical activity count, locomotor time 20.30.31.1-0.7-0.30.10.6-0.00.50.0-0.2-0.9-0.4-1.0-0.9
Light reinforcement 10.10.10.30.5-0.50.30.5-0.30.30.20.1-0.30.1-0.00.3
Light reinforcement 21.01.32.01.0-1.21.11.4-0.91.31.01.1-1.4-0.9-1.3-1.1
Bone: marrow area0.10.20.7-0.80.8-0.8-0.50.3-0.5-0.3-0.30.1-0.1-0.1-0.1
Bone: maximum diameter1.83.44.6-2.12.1-2.1-2.01.9-2.0-1.8-1.81.71.51.51.3
Bone: maximum force1.42.44.4-2.11.9-1.9-1.71.6-1.6-1.6-1.61.31.10.90.9
Bone: maximum moment0.91.63.2-1.81.6-1.6-1.41.3-1.3-1.3-1.31.00.90.70.6
Mean time between licks in bursts0.50.81.71.3-1.00.90.8-1.01.01.01.0-0.6-0.7-0.4-0.4
Mean num. licks in bursts1.92.33.9-1.01.5-1.5-1.71.2-1.7-1.3-1.31.81.32.01.8
Cd content in liver2.83.14.02.0-1.61.51.8-1.92.01.91.8-1.7-1.8-1.7-1.2
Co content in liver1.11.32.30.9-0.80.81.1-1.20.81.21.3-1.3-1.5-1.3-1.3
Cu content in liver0.10.20.4-0.30.4-0.3-0.40.4-0.2-0.4-0.50.40.40.20.6
Fe content in liver7.38.89.8-3.03.1-3.1-3.02.9-3.0-2.9-3.13.02.82.72.9
K content in liver0.40.40.6-0.50.6-0.5-0.70.7-0.6-0.7-0.70.70.80.70.7
Mg content in liver0.00.00.1-0.30.2-0.1-0.10.3-0.0-0.2-0.2-0.00.1-0.1-0.0
Mn content in liver1.82.02.21.4-1.41.51.4-1.41.41.41.5-1.5-1.4-1.4-1.4
Na content in liver0.60.60.7-0.80.8-0.8-0.90.8-0.8-0.8-0.70.80.80.80.7
Rb content in liver0.10.20.60.5-0.30.3-0.10.20.2-0.2-0.10.40.60.60.8
Se content in liver7.49.010.4-2.72.7-2.6-3.13.0-3.0-3.1-3.13.13.23.23.1
Sr content in liver0.90.81.80.4-0.80.81.0-0.70.70.70.7-1.1-0.9-1.1-1.4
Zn content in liver0.50.62.0-1.40.8-0.7-0.60.9-0.8-0.9-1.00.20.60.10.0
Bone: minimum diameter0.10.10.20.3-0.10.10.1-0.40.20.40.4-0.2-0.5-0.3-0.3
Time in familiar zone, hab. session 10.40.40.70.8-0.70.70.5-0.70.40.80.8-0.4-0.7-0.3-0.7
Time in novel zone, hab. session 10.30.30.6-0.80.6-0.5-0.50.7-0.6-0.6-0.70.30.50.30.4
Total zone transitions, hab. session 10.20.20.60.8-0.70.50.7-0.10.60.30.2-0.50.0-0.30.2
Total locomotion distance, hab. session 10.50.71.9-0.40.4-0.4-0.51.0-0.5-1.0-1.00.71.40.81.2
Locomotion velocity, hab. session 10.20.31.10.1-0.10.0-0.10.6-0.1-0.6-0.60.41.00.61.0
Time in familiar zone, hab. session 20.10.10.1-0.20.10.0-0.30.3-0.3-0.2-0.30.30.40.40.2
Time in novel zone, hab. session 20.10.10.30.5-0.30.10.4-0.40.30.40.5-0.3-0.4-0.3-0.1
Total zone transitions, hab. session 20.50.71.30.5-0.70.61.0-0.60.80.70.7-1.0-0.9-1.1-0.9
Total locomotion distance, hab. session 20.10.20.40.4-0.50.30.6-0.20.50.30.3-0.5-0.2-0.5-0.3
Locomotion velocity, hab. session 20.30.30.60.5-0.70.50.8-0.40.70.40.4-0.8-0.4-0.8-0.4
Novel to familiar place preference ratio0.91.01.50.9-0.80.80.8-1.00.91.11.1-0.9-1.2-0.9-1.0
Novelty place preference1.31.31.81.2-1.01.01.0-1.21.11.31.3-1.0-1.3-1.0-1.1
Time in novel zone, NPP test0.80.81.30.9-0.80.80.8-1.00.81.01.1-0.8-1.1-0.8-0.9
Total zone transitions, NPP test0.00.00.1-0.10.2-0.3-0.00.3-0.1-0.1-0.10.00.1-0.00.1
Total locomotion distance, NPP test1.31.82.5-0.91.2-1.3-1.21.5-1.3-1.4-1.31.41.51.41.6
Locomotion velocity, NPP test1.01.42.0-0.81.1-1.3-1.01.3-1.1-1.2-1.21.21.31.11.4
Intraocular pressure2.63.64.5-2.12.0-2.1-1.92.0-1.9-2.0-2.01.71.71.51.6
Delta distance traveled before/after self-admin0.10.10.4-0.4-0.1-0.00.50.30.3-0.2-0.3-0.60.1-0.6-0.4
Delta ambulatory time before/after self-admin0.10.10.2-0.0-0.20.20.40.10.3-0.0-0.1-0.4-0.0-0.4-0.3
Parametrial fat weight0.40.71.60.3-0.81.11.0-0.61.00.60.6-1.0-0.6-1.0-1.3
Pavlov. Cond. lever latency0.20.31.0-1.00.8-0.6-0.50.4-0.5-0.5-0.40.20.1-0.1-0.3
Pavlov. Cond. magazine entry latency0.10.20.4-0.40.5-0.7-0.40.4-0.6-0.3-0.20.40.10.30.3
Pavlov. Cond. change in total contacts0.10.20.40.00.0-0.2-0.20.4-0.4-0.4-0.40.40.60.60.6
Pavlov. Cond. index score0.30.40.7-0.30.5-0.6-0.60.6-0.7-0.5-0.50.70.60.80.8
Pavlov. Cond. latency score0.20.30.7-0.10.3-0.5-0.40.5-0.6-0.4-0.40.60.60.70.8
Pavlov. Cond. lever contacts0.10.10.40.6-0.40.30.2-0.10.20.20.10.00.20.30.5
Pavlov. Cond. magazine entry number0.91.11.90.8-1.21.41.1-1.01.20.90.8-1.1-0.7-1.0-1.1
Pavlov. Cond. intertrial magazine entries1.11.42.21.5-1.11.01.2-1.21.21.21.3-1.1-1.2-1.0-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.30.6-0.30.5-0.6-0.50.6-0.7-0.5-0.50.70.60.80.8
Pavlov. Cond. response bias0.60.71.0-0.60.9-1.0-0.80.8-1.0-0.8-0.70.90.80.91.0
Pavlov. Cond. lever latency0.71.01.80.6-1.01.11.0-0.81.00.90.9-1.1-1.0-1.1-1.3
Pavlov. Cond. magazine entry latency0.30.30.90.20.1-0.2-0.40.6-0.4-0.4-0.30.60.80.80.9
Pavlov. Cond. change in total contacts0.20.30.5-0.20.5-0.6-0.50.5-0.4-0.5-0.40.60.50.50.7
Pavlov. Cond. index score0.40.51.4-0.10.5-0.6-0.60.6-0.6-0.6-0.60.80.90.91.2
Pavlov. Cond. latency score0.40.61.4-0.10.5-0.6-0.70.7-0.6-0.7-0.60.80.90.91.2
Pavlov. Cond. lever contacts1.62.23.4-0.91.3-1.4-1.51.3-1.5-1.4-1.41.61.61.71.8
Pavlov. Cond. magazine entry number0.10.10.4-0.60.2-0.0-0.1-0.1-0.10.0-0.0-0.1-0.4-0.3-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.10.3-0.1-0.1-0.40.10.30.3-0.1-0.6-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.10.4-0.5-0.50.5-0.4-0.5-0.40.60.70.71.0
Pavlov. Cond. response bias1.52.03.8-0.71.2-1.3-1.41.3-1.3-1.3-1.31.51.61.72.0
Time in closed arm before self-admin0.10.10.5-0.70.4-0.30.10.4-0.0-0.3-0.3-0.30.1-0.6-0.4
Time in closed arm after self-admin0.10.10.5-0.50.3-0.40.10.20.1-0.1-0.3-0.5-0.2-0.7-0.1
Time in open arm before self-admin0.00.00.1-0.2-0.1-0.1-0.10.10.0-0.1-0.30.2-0.00.00.0
Time in open arm after self-admin0.20.20.70.10.2-0.2-0.50.1-0.4-0.10.10.80.20.90.3
Bone: periosteal estimation1.32.74.4-2.12.0-2.0-1.71.6-1.8-1.6-1.71.41.21.11.0
Bone: periosteal perimeter3.25.47.0-2.22.5-2.6-2.52.3-2.5-2.2-2.12.32.12.12.2
Bone: post-yield work1.41.92.2-1.41.4-1.4-1.41.4-1.3-1.4-1.51.31.41.21.4
Progressive ratio test 1 active lever presses0.10.10.3-0.3-0.0-0.20.30.10.2-0.1-0.2-0.5-0.1-0.6-0.3
Progressive ratio test 1 breakpoint0.10.10.5-0.3-0.1-0.10.4-0.00.30.0-0.2-0.6-0.2-0.7-0.5
Progressive ratio test 1 inactive lever presses0.30.31.1-0.1-0.10.00.6-0.20.60.20.0-0.9-0.5-1.1-0.7
Progressive ratio test 2 active lever presses0.30.31.1-0.90.5-1.0-0.00.6-0.3-0.6-0.8-0.10.3-0.40.2
Progressive ratio test 2 breakpoint0.10.10.6-0.4-0.0-0.60.40.20.2-0.1-0.3-0.5-0.1-0.7-0.0
Progressive ratio test 2 inactive lever presses0.40.42.0-0.90.9-1.4-0.30.5-0.5-0.5-0.6-0.1-0.1-0.50.1
Incentive Sensitization - Responses0.00.00.1-0.0-0.1-0.40.3-0.10.20.0-0.2-0.2-0.0-0.30.3
Incentive Sensitization - Breakpoint0.00.00.2-0.0-0.0-0.50.2-0.00.10.0-0.2-0.2-0.0-0.30.4
Sum of active levers in priming session hrs 5-61.51.43.1-0.90.8-0.7-1.01.4-0.9-1.4-1.41.11.71.41.2
Progressive ratio1.72.02.71.6-1.41.21.3-1.61.31.61.7-1.2-1.5-1.1-1.2
Food seeking constrained by brief footshock0.80.91.51.1-0.91.01.0-1.21.01.01.0-0.8-0.9-0.8-0.7
Seeking ratio, punishment vs. effort0.81.01.7-1.31.1-0.9-1.01.0-0.9-1.2-1.30.81.00.60.7
Retroperitoneal fat weight0.93.17.1-0.71.0-0.9-1.71.5-1.7-1.5-1.52.22.22.72.1
Reaction time number correct0.10.10.3-0.40.3-0.3-0.00.30.0-0.2-0.1-0.2-0.0-0.5-0.2
Reaction time mean minus median2.93.95.7-1.32.2-1.9-2.21.7-2.2-1.7-1.52.41.72.32.2
Reaction time mean minus median AUC0.40.61.40.00.9-0.8-0.80.4-0.9-0.4-0.31.00.51.01.2
Reaction time num false alarms0.30.40.9-0.00.6-0.7-0.70.4-0.7-0.4-0.10.80.30.81.0
Reaction time num false alarms AUC0.81.12.1-0.51.1-1.2-1.20.9-1.2-0.9-0.71.20.81.21.5
Reaction time trials correct on left0.10.10.3-0.40.3-0.3-0.00.30.0-0.2-0.1-0.2-0.0-0.5-0.2
Reaction time trials on left0.00.10.3-0.40.3-0.3-0.00.20.0-0.2-0.1-0.2-0.1-0.5-0.2
Reaction time mean0.50.72.11.4-1.01.00.7-1.10.61.00.8-0.1-0.60.2-0.0
Reaction time mean AUC0.40.51.81.3-0.90.90.5-0.90.50.80.70.0-0.40.30.1
Median of all reaction times1.72.34.72.2-1.91.81.5-1.81.51.71.5-0.9-1.2-0.5-0.7
Reaction time omissions0.20.20.80.9-0.10.1-0.2-0.5-0.10.50.60.6-0.30.70.6
Reaction time false alarm rate0.81.22.2-0.41.0-1.1-1.20.8-1.2-0.8-0.71.30.91.41.5
Reaction time premature initiation rate0.00.00.1-0.10.3-0.2-0.10.2-0.2-0.2-0.20.10.30.30.3
Reaction time premature initiations0.00.10.2-0.20.4-0.3-0.10.3-0.1-0.3-0.20.00.20.00.2
Std. dev. reaction times0.50.82.0-0.10.8-0.6-0.90.5-1.0-0.5-0.51.20.71.41.3
Reaction time trials completed0.00.10.3-0.40.3-0.3-0.00.20.0-0.2-0.1-0.2-0.1-0.5-0.2
Reaction time trials AUC0.00.10.2-0.40.3-0.3-0.00.30.0-0.3-0.2-0.10.0-0.4-0.0
Run reversals in cocaine runway, females0.00.00.20.0-0.00.00.00.40.0-0.3-0.20.10.50.10.3
Run reversals in cocaine runway, males1.01.01.70.9-0.70.60.9-1.10.91.11.1-1.0-1.3-1.1-0.8
Latency to leave start box in cocaine runway0.20.20.30.4-0.60.50.6-0.30.40.30.2-0.4-0.2-0.3-0.6
Latency to leave start box in cocaine runway, F0.20.20.7-0.1-0.50.50.50.00.4-0.1-0.0-0.60.0-0.5-0.9
Latency to leave start box in cocaine runway, M0.10.10.30.40.1-0.30.1-0.1-0.10.10.10.1-0.00.20.6
Std. dev. time between licks in bursts0.40.51.0-0.50.9-1.0-0.80.6-0.6-0.6-0.50.70.50.60.8
Total sessions with >9 infusions0.10.10.2-0.30.3-0.4-0.20.4-0.4-0.3-0.30.30.30.30.3
Short access day 1 total inactive lever presses0.80.91.30.9-0.80.70.9-0.90.71.01.1-1.0-1.1-1.0-1.0
Short access day 10 total inactive lever presses0.20.20.7-0.80.6-0.5-0.60.4-0.5-0.4-0.40.20.00.1-0.3
Short access day 1 total infusions0.70.71.21.0-1.11.10.9-1.00.71.00.8-0.7-0.6-0.4-0.6
Short access day 10 total infusions0.00.00.10.3-0.30.10.2-0.10.1-0.0-0.10.10.30.20.3
Short access total infusions0.30.30.80.6-0.90.90.6-0.50.50.50.3-0.5-0.2-0.2-0.5
Short access day 1 locomotion0.40.41.01.0-0.70.60.7-0.60.70.70.7-0.5-0.4-0.3-0.0
Short access day 10 total locomotion0.10.20.40.7-0.10.20.0-0.50.10.50.50.4-0.30.50.3
Short access total locomotion0.10.10.40.6-0.30.40.1-0.20.20.20.30.30.10.50.4
One hour access (0.3 mA shock)0.91.02.40.8-0.60.11.1-0.81.10.91.0-1.4-1.2-1.6-0.7
Compulsive drug intake3.83.85.12.3-2.12.12.1-1.82.32.02.1-1.9-1.6-1.7-1.3
One hour access (shock baseline)0.91.02.8-1.21.3-1.7-1.00.9-1.0-1.0-1.10.60.60.40.8
Social response proportion0.91.03.1-1.81.1-0.8-0.81.3-0.7-1.3-1.30.50.90.00.2
Social responses1.62.13.4-1.81.7-1.5-1.31.7-1.4-1.6-1.61.11.30.81.2
Social time1.82.43.82.0-1.61.71.7-1.41.71.61.7-1.5-1.3-1.2-0.9
Soleus weight2.57.39.7-3.12.9-2.9-2.72.9-2.8-2.8-3.02.42.62.12.2
Bone: stiffness0.61.01.8-1.21.3-1.3-1.10.9-1.1-0.9-1.00.80.70.70.9
Tibialis anterior weight6.923.734.1-5.85.3-5.2-5.05.0-5.0-5.1-5.24.44.43.93.6
Time to tail flick, vehicle, before self-admin0.40.41.30.6-1.01.20.6-0.50.80.50.4-0.3-0.2-0.3-0.2
Time to tail flick, vehicle, after self-admin0.10.10.20.3-0.30.50.50.00.4-0.00.0-0.30.1-0.20.0
Time to tail flick, test, before self-admin0.20.20.7-0.80.2-0.2-0.30.6-0.3-0.6-0.70.10.4-0.1-0.1
Time to tail flick, test, after self-admin0.40.51.2-0.80.2-0.2-0.40.9-0.3-1.0-0.90.51.10.60.4
Delta time to tail flick, vehicle, before/after SA0.00.00.10.2-0.0-0.10.20.00.10.00.1-0.20.0-0.10.1
Delta time to tail flick, test, before/after SA0.30.20.7-0.10.4-0.3-0.40.3-0.4-0.3-0.20.70.60.80.6
Tibia length0.31.04.6-2.11.1-0.8-0.81.0-0.7-1.0-1.10.20.3-0.3-0.8
Ambulatory time before self-admin0.70.71.9-0.20.8-0.8-0.90.5-0.9-0.6-0.51.00.81.11.4
Ambulatory time after self-admin0.70.71.1-0.70.7-0.8-0.70.9-0.9-0.9-0.90.81.00.81.0
Bone: tissue strength0.40.30.60.4-0.60.50.6-0.50.60.50.5-0.7-0.5-0.7-0.8
Total heroin consumption0.40.41.90.50.3-0.2-0.30.3-0.3-0.4-0.30.70.81.01.4
Bone: trabecular number5.07.811.9-3.53.0-2.7-3.02.9-2.9-2.9-3.02.62.52.31.9
Bone: trabecular spacing3.14.07.12.7-2.22.02.1-2.12.12.12.2-1.8-1.7-1.4-1.1
Bone: trabecular thickness9.511.314.5-3.83.6-3.4-3.53.5-3.5-3.5-3.53.23.22.92.7
Bone: trabecular tissue density0.91.21.7-0.81.0-1.1-1.01.1-1.2-1.1-1.11.11.21.21.3
Water consumed over 24 hours0.30.31.1-0.20.2-0.20.2-0.50.10.50.5-0.6-1.1-0.9-0.9
Number of responses in last shaping day0.10.10.30.3-0.20.10.3-0.50.20.50.4-0.4-0.6-0.3-0.3