Hub : Traits : Tibialis anterior weight : ← : →

chr2:101,703,742-104,760,530

Trait: Tibialis anterior weight

Best TWAS P = 6.92e-08 · Best GWAS P= 3.93e-08 conditioned to 1.20e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Mtfr1	mRNA stability	Mtfr1	0.08	1	0.04	5.4e-05	5.38	7.28e-08	0.33	FALSE
BLA	Cyp7b1	alternative polyA	XM_039101794.2	0.12	1	0.02	4.6e-02	5.23	1.67e-07	0.04	FALSE
BLA	Cyp7b1	alternative polyA	NM_019138.1	0.15	1	0.02	3.0e-02	-5.23	1.67e-07	0.04	FALSE
BLA	Cyp7b1	alternative polyA	XM_063281357.1	0.14	1	0.02	3.6e-02	5.23	1.67e-07	0.04	FALSE
BLA	Cyp7b1	gene expression	Cyp7b1	0.4	2321	0.22	4.3e-12	5.33	9.96e-08	0.44	FALSE
BLA	Cyp7b1	isoform ratio	XM_063281357.1	0.25	42	0.11	1.3e-06	-5.27	1.37e-07	0.31	FALSE
Brain	Bhlhe22	gene expression	Bhlhe22	0.08	1	0.05	1.8e-05	5.22	1.74e-07	0.19	FALSE
Brain	Cyp7b1	isoform ratio	NM_019138.1	0.08	2321	0.04	3.1e-04	5.29	1.22e-07	0.39	FALSE
Brain	Cyp7b1	mRNA stability	Cyp7b1	0.06	1	0.04	1.3e-04	-5.28	1.29e-07	0.11	FALSE
IC	Cyp7b1	gene expression	Cyp7b1	0.14	1538	0.05	4.4e-03	5.32	1.05e-07	0.28	FALSE
Liver	Mtfr1	gene expression	Mtfr1	0.29	48	0.2	2.9e-22	-5.33	9.71e-08	0.67	FALSE
NAcc	Armc1	gene expression	Armc1	0.05	1548	0.04	1.8e-06	-5.26	1.46e-07	0.55	FALSE
NAcc	Cyp7b1	gene expression	Cyp7b1	0.1	1	0.09	4.4e-14	-5.28	1.29e-07	0.48	FALSE
NAcc	Mtfr1	gene expression	Mtfr1	0.08	1	0.08	1.3e-11	5.34	9.37e-08	0.75	FALSE
NAcc	Pde7a	gene expression	Pde7a	0.03	1	0.03	1.0e-04	5.39	6.92e-08	0.39	TRUE
OFC	Crh	gene expression	Crh	0.2	1	0.05	2.2e-02	5.32	1.06e-07	0.16	FALSE
PL	Cyp7b1	alternative polyA	NM_019138.1	0.05	1	0.04	1.3e-05	-5.31	1.10e-07	0.26	FALSE
PL	Cyp7b1	alternative polyA	XM_039101794.2	0.05	1	0.04	1.9e-05	5.31	1.10e-07	0.23	FALSE
PL	Cyp7b1	alternative polyA	NM_019138.1	0.05	1	0.04	2.6e-05	-5.31	1.10e-07	0.33	FALSE
PL	Cyp7b1	alternative polyA	XM_063281357.1	0.05	1	0.05	9.3e-06	5.31	1.10e-07	0.31	FALSE
PL	Cyp7b1	gene expression	Cyp7b1	0.1	199	0.09	2.3e-10	-5.22	1.78e-07	0.42	FALSE
PL	Cyp7b1	isoform ratio	XM_039101794.2	0.03	1	0.02	3.8e-03	-5.3	1.15e-07	0.03	FALSE
pVTA	Cyp7b1	gene expression	Cyp7b1	0.08	1538	0.05	1.1e-04	5.36	8.22e-08	0.41	FALSE
pVTA	Cyp7b1	intron excision ratio	chr2_102554587_102585672	0.03	1538	0.01	3.2e-02	5.33	9.78e-08	0.26	FALSE