Hub : Genes

Iqck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Iqck 0.38 0.11 0.0e+00 0.22 0.26 0.26 0.27 1.4e-24 2.4e-28 5.9e-29 9.2e-30
2 Adipose isoform ratio XM_063283526.1 0.14 0.06 3.7e-13 0.08 0.08 0.06 0.08 3.3e-09 2.0e-09 9.2e-08 7.1e-09
3 OFC gene expression Iqck 0.28 0.14 4.1e-03 0.05 0.04 0.02 0.05 2.6e-02 4.4e-02 1.3e-01 3.1e-02
4 NAcc intron excision ratio chr1_182630887_182648437 0.03 0.02 2.1e-04 0.02 0.02 0.02 0.02 9.6e-04 9.7e-04 2.6e-04 6.0e-04
5 Brain alternative polyA NM_001401714.1 0.06 0.04 2.9e-04 0.05 0.03 0.04 0.04 1.1e-05 6.4e-04 2.1e-04 7.3e-05
6 Brain alternative polyA XM_039101165.2 0.07 0.04 2.0e-04 0.06 0.04 0.04 0.05 6.6e-06 3.2e-04 1.3e-04 3.6e-05
7 Adipose alternative TSS XM_063283495.1 0.04 0.04 1.6e-03 0.02 0.02 0.02 0.02 6.1e-03 2.2e-03 5.3e-03 1.1e-03
8 LHb gene expression Iqck 0.39 0.16 3.3e-04 0.02 0.09 0.05 0.06 1.2e-01 3.5e-03 2.7e-02 1.8e-02
9 Adipose alternative TSS XM_039101167.2 0.03 0.02 3.0e-03 0.01 0 0 0.01 2.2e-02 9.2e-02 1.6e-01 6.2e-02
10 NAcc gene expression Iqck 0.1 0.05 1.1e-06 0.04 0.05 0.05 0.06 3.6e-07 5.5e-08 1.1e-07 5.0e-09
11 PL gene expression Iqck 0.08 0.05 4.9e-05 0.02 0.05 0.06 0.05 3.8e-03 3.1e-06 4.8e-07 2.5e-06
12 NAcc isoform ratio NM_001401714.1 0.03 0.02 7.6e-03 0.01 0 0.01 0.01 2.1e-03 1.3e-01 8.2e-03 1.4e-02
13 Brain gene expression Iqck 0.13 0.06 7.6e-08 0.08 0.09 0.08 0.09 1.0e-07 1.1e-08 3.5e-08 1.3e-08
14 PL intron excision ratio chr1_182630887_182648437 0.02 0.02 9.0e-03 0.01 0.01 0.01 0 1.3e-02 6.2e-02 2.2e-02 7.7e-02
15 PL isoform ratio XM_063283526.1 0.06 0.04 1.8e-03 0.02 0.02 0.01 0.01 6.1e-03 1.8e-03 1.0e-02 2.2e-02
16 Brain intron excision ratio chr1_182648510_182652112 0.04 0.02 5.1e-03 0.02 0.02 0.01 0.02 3.2e-03 4.4e-03 4.7e-02 1.1e-02
17 BLA gene expression Iqck 0.18 0.08 2.3e-06 0.06 0.12 0.08 0.11 4.8e-04 8.4e-07 3.8e-05 1.6e-06
18 Adipose alternative TSS XM_063283495.1 0.13 0.14 3.2e-05 0.03 0.03 0.03 0.04 3.1e-04 4.4e-04 3.3e-04 8.2e-05
19 PL intron excision ratio chr1_182648510_182652112 0.07 0.04 1.1e-04 0.02 0.03 0.03 0.03 5.3e-03 3.1e-04 3.4e-04 7.1e-04
20 IC gene expression Iqck 0.12 0.07 3.3e-03 0.02 0.05 0.03 0.04 5.2e-02 3.1e-03 1.5e-02 6.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.40.72.8-1.3-1.71.20.81.2-1.21.0-0.1-0.7-0.2-0.7-0.20.2-0.1-0.1-0.31.0-0.3-0.80.9
Area under the delay curve0.30.41.20.20.4-0.9-0.5-0.60.61.10.8-0.00.5-1.00.50.7-0.5-1.10.40.50.4-0.1-0.4
BMI with tail1.75.818.3-3.4-3.94.33.62.8-2.80.1-2.2-1.7-2.41.0-2.2-1.62.21.7-2.30.8-2.2-0.61.7
BMI without tail1.47.223.8-4.1-4.94.63.64.1-4.11.2-1.8-2.1-1.7-0.2-1.6-1.01.71.4-1.81.5-1.6-1.62.5
Body weight1.04.413.6-3.5-3.73.52.83.2-3.20.8-1.6-2.1-1.3-0.2-1.1-0.91.11.3-1.20.8-1.0-1.41.8
Weight adjusted by age0.41.34.9-0.2-0.11.30.51.4-1.4-2.2-1.5-0.3-0.51.7-0.6-1.30.92.1-0.6-1.4-0.50.30.4
Bone surface0.51.13.1-1.8-1.31.41.41.0-1.00.4-1.0-1.5-1.20.2-1.1-0.80.90.4-1.10.2-1.20.3-0.1
Bone volume0.61.23.9-2.0-2.01.71.61.3-1.30.9-0.7-1.3-0.9-0.2-0.9-0.40.70.1-1.00.8-1.0-0.30.5
Breakpoint value in progressive ratio session0.51.02.21.31.4-0.9-1.4-0.70.7-1.50.20.71.40.21.20.2-1.00.91.2-1.21.3-0.40.2
Number of licking bursts0.92.78.72.42.8-2.7-1.8-3.03.0-0.31.11.60.30.40.10.3-0.2-1.4-0.0-0.40.11.7-2.0
Context. condit. distance diff. score0.20.30.70.60.6-0.3-0.70.2-0.2-0.80.10.40.60.20.50.1-0.80.50.8-0.60.8-0.30.2
Locomotion velocity, session 10.20.20.8-0.2-0.1-0.30.0-0.70.70.80.3-0.30.1-0.4-0.30.2-0.1-0.9-0.10.6-0.10.3-0.5
Locomotion distance, session 10.40.51.5-0.9-1.21.10.61.2-1.20.2-0.4-0.70.4-0.2-0.0-0.0-0.30.50.10.30.1-0.80.9
Locomotion velocity, session 20.20.31.10.10.2-0.8-0.2-0.70.70.90.6-0.20.2-0.60.10.5-0.1-1.00.10.60.10.1-0.4
Locomotion distance, session 20.60.93.4-1.8-1.71.41.30.7-0.70.9-0.7-1.5-0.6-0.2-0.9-0.40.40.0-0.80.7-0.8-0.20.3
Locomotion velocity, session 30.10.20.9-0.9-0.60.50.50.3-0.30.2-0.4-0.9-0.1-0.0-0.2-0.2-0.10.3-0.2-0.0-0.2-0.20.1
Locomotion distance, session 31.11.22.1-1.00.20.50.8-0.90.9-0.3-1.3-1.5-1.21.2-1.5-1.40.90.5-1.5-0.8-1.41.4-1.3
Stereotopy head waving bouts, day 30.50.61.51.00.6-0.8-1.00.0-0.0-0.10.80.91.1-0.61.20.9-1.0-0.21.2-0.01.2-0.80.5
Stereotopy head waving duration, day 30.50.61.40.60.1-0.5-0.70.8-0.80.10.70.71.1-0.81.20.9-0.8-0.11.20.21.2-1.00.8
Locomotion velocity, session 72.32.56.7-2.2-0.51.32.2-0.10.1-0.4-2.0-2.6-2.11.4-1.9-1.92.11.2-1.7-1.1-1.51.2-1.2
Locomotion distance, session 71.11.43.2-0.70.60.11.1-1.11.1-0.2-1.1-1.3-1.81.2-1.4-1.31.80.3-1.2-0.8-1.11.6-1.6
Stereotopy head waving bouts, day 70.30.41.2-0.4-0.50.2-0.31.0-1.00.10.1-0.41.1-0.50.60.4-1.10.20.40.10.5-0.90.7
Stereotopy head waving duration, day 70.91.13.9-1.5-1.61.50.92.0-2.0-0.2-0.8-1.10.2-0.0-0.2-0.3-0.20.9-0.40.1-0.3-0.91.1
Locomotion velocity, session 80.10.10.7-0.2-0.2-0.1-0.4-0.20.20.50.2-0.20.7-0.40.20.3-0.8-0.30.10.30.1-0.30.1
Locomotion distance, session 80.10.10.5-0.6-0.50.60.30.3-0.3-0.1-0.4-0.7-0.00.2-0.3-0.2-0.20.30.1-0.00.1-0.20.3
Degree of sensitization distance0.91.01.90.9-0.1-0.6-0.60.6-0.60.71.31.30.6-1.31.31.4-0.4-0.71.30.91.4-1.21.0
Degree of sensitization stereotypy0.60.72.6-1.6-1.41.10.91.1-1.10.3-0.7-1.4-0.0-0.1-0.5-0.4-0.10.4-0.50.2-0.5-0.40.4
Conditioned locomotion0.91.12.30.11.3-0.30.3-1.21.2-1.2-1.0-0.8-1.01.4-0.8-1.21.00.8-0.8-1.5-0.71.4-1.4
Cocaine response after cond. corrected0.10.10.50.50.5-0.6-0.2-0.70.70.10.30.4-0.2-0.10.10.2-0.1-0.40.00.10.00.3-0.3
Cocaine response after cond. not corrected0.10.10.4-0.4-0.20.20.5-0.10.10.2-0.3-0.4-0.60.2-0.4-0.40.4-0.0-0.5-0.0-0.50.4-0.3
Cocaine response before conditioning1.41.75.2-2.3-1.31.61.80.7-0.70.4-1.5-2.0-1.30.6-1.5-1.31.50.6-1.5-0.1-1.60.6-0.5
Saline control response0.30.40.90.80.1-0.4-0.70.3-0.3-0.00.70.60.9-0.60.90.7-0.8-0.10.80.21.0-0.70.7
Bone: connectivity density0.40.61.8-1.1-1.11.30.91.1-1.1-0.1-0.8-0.9-0.50.2-0.5-0.50.30.7-0.60.0-0.6-0.30.5
Bone: cortical apparent density0.40.72.01.21.2-1.4-1.2-1.21.20.30.90.80.4-0.30.40.6-0.6-1.00.60.20.50.5-0.7
Bone: cortical area1.11.96.5-2.6-2.31.92.11.2-1.21.4-0.8-1.5-1.5-0.4-1.2-0.51.2-0.1-1.31.1-1.1-0.20.3
Bone: cortical porosity0.60.61.8-1.0-0.91.30.81.1-1.1-0.7-1.0-0.8-0.40.5-0.1-0.60.41.4-0.3-0.6-0.3-0.50.8
Bone: cortical porosity0.40.52.2-0.6-0.40.90.40.9-0.9-1.0-0.8-0.6-0.10.40.3-0.40.01.50.1-0.90.2-0.70.8
Bone: cortical thickness0.71.15.3-1.5-1.70.41.00.2-0.22.30.6-0.6-0.7-1.4-0.30.70.5-1.5-0.31.9-0.2-0.50.3
Bone: cortical thickness1.11.46.7-0.6-1.0-0.60.1-0.90.92.61.4-0.00.3-1.90.21.3-0.1-2.20.22.20.2-0.50.1
Bone: cortical tissue density0.40.71.91.21.2-1.4-1.2-1.21.20.20.90.80.4-0.30.40.6-0.6-0.90.70.20.50.4-0.7
Condit. Reinf. active minus inactive responses0.20.20.60.50.20.0-0.50.3-0.3-0.50.10.20.3-0.00.60.2-0.70.50.7-0.40.7-0.60.5
Condit. Reinf. active-inactive response ratio0.30.31.30.10.20.5-0.10.7-0.7-1.0-0.5-0.3-0.00.60.2-0.4-0.31.10.3-0.90.3-0.30.4
Condit. Reinf. active responses0.20.20.50.60.1-0.2-0.40.0-0.0-0.20.50.60.0-0.20.60.5-0.50.00.70.10.7-0.60.6
Condit. Reinf. inactive responses0.10.20.60.4-0.2-0.2-0.1-0.30.30.30.60.8-0.1-0.50.30.6-0.1-0.50.30.70.3-0.40.5
Incentive salience index mean0.20.30.8-0.20.10.60.50.1-0.1-0.8-0.7-0.5-0.90.9-0.5-0.70.40.8-0.4-0.7-0.40.4-0.1
Condit. Reinf. lever presses0.60.92.5-0.20.30.60.9-0.30.3-1.3-1.2-0.6-1.31.6-1.0-1.31.11.1-1.0-1.1-1.01.0-0.6
Condit. Reinf. active minus inactive responses0.81.34.70.1-1.31.2-0.02.0-2.0-0.50.10.80.9-0.40.70.5-0.80.90.90.40.8-1.82.2
Condit. Reinf. active-inactive response ratio0.81.33.90.9-0.60.5-0.61.5-1.5-0.60.61.51.2-0.51.20.9-1.10.61.40.31.2-1.72.0
Condit. Reinf. active responses0.50.73.0-0.2-1.11.30.21.7-1.7-0.5-0.30.30.40.00.20.1-0.51.00.40.10.2-1.21.5
Condit. Reinf. inactive responses0.81.22.6-1.6-0.81.21.40.4-0.4-0.0-1.4-1.6-1.30.8-1.3-1.31.10.7-1.4-0.4-1.50.7-0.6
Condit. Reinf. lever presses0.81.14.5-1.0-1.61.90.82.1-2.1-0.4-0.7-0.20.10.2-0.2-0.3-0.21.2-0.20.1-0.2-1.01.5
Condit. Reinf. lever reinforcers received0.50.72.70.1-0.81.0-0.01.6-1.6-0.8-0.20.50.50.10.50.1-0.61.10.6-0.20.4-1.11.5
Conditioned reinforcement - actives0.20.63.4-0.2-0.4-0.3-0.2-0.10.11.90.9-0.20.9-1.50.31.0-0.4-1.20.41.00.4-0.60.1
Conditioned reinforcement - inactives0.30.82.81.00.6-1.3-0.9-0.60.61.41.31.00.9-1.00.21.0-0.6-1.70.51.00.20.2-0.4
Conditioned locomotion0.10.10.30.10.2-0.5-0.2-0.00.00.60.4-0.00.5-0.40.00.3-0.1-0.60.20.30.10.1-0.3
Patch foraging indifference point 0 sec0.51.54.40.1-1.10.5-0.51.5-1.50.50.90.61.6-1.31.31.3-1.7-0.01.20.91.6-2.11.9
Patch foraging indifference point AUC0.20.52.5-0.3-1.10.50.20.7-0.71.30.70.50.1-0.8-0.30.7-0.1-1.1-0.21.6-0.1-0.40.6
Delay disc. indifference point, 0s delay0.91.02.3-1.1-0.60.41.2-0.80.81.5-0.3-1.3-0.8-0.1-1.4-0.51.0-1.0-1.20.8-1.11.1-1.2
Delay disc. indifference point, 16s delay2.12.96.52.52.0-2.4-2.5-1.31.30.01.81.72.1-1.22.11.7-2.0-0.92.0-0.12.0-0.70.1
Delay disc. indifference point, 2s delay1.82.05.6-2.4-2.01.82.40.6-0.61.4-1.1-1.9-1.5-0.0-1.6-0.91.5-0.1-1.60.9-1.60.4-0.2
Delay disc. indifference point, 24s delay1.01.65.01.72.0-2.2-2.1-1.51.5-0.21.11.11.1-0.51.30.8-1.3-0.81.2-0.50.90.3-0.7
Delay disc. indifference point, 4s delay0.80.84.2-0.3-0.4-0.7-0.2-0.70.72.01.1-0.00.3-1.60.31.0-0.3-1.80.31.50.1-0.2-0.2
Delay disc. indifference point, 8s delay0.10.21.1-0.50.1-0.40.2-0.40.41.00.2-0.8-0.4-0.5-0.20.10.4-0.8-0.40.3-0.30.4-0.8
Indifference point function ln k0.00.10.4-0.5-0.50.20.6-0.10.10.2-0.2-0.3-0.3-0.20.0-0.00.50.0-0.00.1-0.1-0.20.2
Indifference point function log k0.00.10.4-0.5-0.50.20.6-0.10.10.2-0.2-0.3-0.3-0.20.0-0.00.50.0-0.00.1-0.1-0.20.2
Patch foraging total patch changes 0 sec0.71.95.50.1-1.20.6-0.51.8-1.80.51.00.81.7-1.41.41.4-1.80.01.31.01.8-2.32.2
Patch foraging total patch changes 12 sec0.20.20.9-0.0-0.50.7-0.01.0-1.0-0.1-0.00.10.40.1-0.00.1-0.60.4-0.00.20.3-0.60.7
Patch foraging total patch changes 18 sec0.30.71.80.5-0.3-0.3-0.80.5-0.50.91.10.81.0-1.00.61.1-1.3-0.90.51.10.9-0.80.7
Patch foraging total patch changes 24 sec0.31.02.5-0.3-1.20.6-0.21.6-1.60.90.70.10.9-1.10.61.0-1.1-0.30.61.10.9-1.51.4
Patch foraging total patch changes 6 sec3.05.19.21.6-0.6-0.9-2.20.8-0.81.52.82.43.0-2.72.53.0-3.0-1.72.52.22.8-2.82.4
Patch foraging time to switch 0 sec0.62.37.01.02.5-1.0-0.5-1.51.5-2.3-1.3-0.7-0.62.2-0.6-1.60.51.4-0.6-2.6-0.62.0-2.0
Patch foraging water rate 0 sec0.10.20.7-0.6-0.80.60.50.8-0.80.1-0.10.1-0.1-0.30.10.10.20.20.10.4-0.0-0.50.6
Patch foraging water rate 12 sec0.41.53.7-0.8-1.70.60.21.5-1.51.40.80.20.8-1.91.11.2-0.8-0.51.11.40.9-1.91.7
Patch foraging water rate 18 sec0.30.62.1-0.4-0.90.50.11.1-1.10.10.30.20.5-0.91.00.6-0.50.41.00.30.8-1.41.3
Patch foraging water rate 24 sec0.30.52.2-0.9-1.00.10.60.3-0.31.50.5-0.30.1-1.20.20.60.3-0.90.21.10.1-0.50.3
Patch foraging water rate 6 sec0.91.33.40.6-0.6-0.7-0.60.4-0.41.51.71.50.8-1.70.91.6-1.0-1.70.91.80.9-1.00.9
Seeking ratio, delayed vs. immediate footshock0.00.10.1-0.1-0.40.10.30.3-0.30.10.10.0-0.1-0.1-0.00.20.3-0.1-0.00.30.3-0.40.4
Distance traveled before self-admin0.20.41.8-0.7-0.6-0.20.50.1-0.11.30.6-0.0-0.4-0.8-0.20.50.6-1.3-0.41.2-0.3-0.0-0.1
Distance traveled after self-admin0.91.64.0-2.0-1.30.91.70.2-0.21.7-0.6-1.5-1.6-0.1-1.6-0.61.8-0.9-1.61.0-1.60.9-0.8
Extensor digitorum longus weight2.811.129.9-5.5-3.64.24.91.3-1.31.5-3.4-4.4-3.91.6-4.3-3.13.90.8-4.30.5-3.91.9-1.3
Bone: elastic displacement1.01.32.21.10.3-1.3-1.4-0.20.20.81.51.41.3-1.31.51.5-1.5-1.01.10.81.2-1.00.7
Bone: elastic work0.20.21.0-0.6-0.90.10.40.3-0.31.00.3-0.1-0.3-0.60.10.4-0.1-0.5-0.20.8-0.1-0.50.4
Bone: endosteal estimation1.22.96.6-2.2-1.62.62.21.8-1.8-0.6-2.2-1.9-1.71.5-1.9-1.91.51.6-2.0-0.6-1.90.7-0.1
Bone: endosteal perimeter1.12.74.7-1.9-0.91.92.10.6-0.6-0.7-2.1-1.7-2.01.7-2.1-2.11.71.3-2.2-0.8-2.11.3-0.8
Epididymis fat weight0.31.65.5-1.4-2.32.01.32.3-2.30.5-0.4-0.2-0.4-0.6-0.10.10.10.7-0.00.9-0.2-1.41.8
Delta time in closed arm before/after self-admin2.01.83.5-0.90.40.71.1-0.80.8-0.9-1.8-1.5-1.51.7-1.6-1.91.41.2-1.7-1.3-1.61.7-1.4
Delta time in open arm before/after self-admin0.50.62.5-0.9-1.61.30.81.1-1.10.8-0.00.0-0.1-0.4-0.20.2-0.1-0.0-0.11.0-0.2-0.81.1
Diff in mean of infusions in LGA sessions1.01.93.91.2-0.4-0.6-1.10.9-0.90.31.62.01.8-1.31.61.8-1.5-0.71.51.21.6-1.71.8
Delay discount exponential model param0.30.30.9-0.2-0.50.90.50.7-0.7-1.0-0.70.1-0.40.8-0.4-0.60.41.0-0.3-0.4-0.3-0.10.5
Extinction: sum of active levers before priming0.20.31.41.00.9-0.3-0.7-0.50.5-1.2-0.20.70.40.80.1-0.3-0.40.60.1-0.80.10.4-0.2
Active lever presses in extinction session 60.20.20.6-0.0-0.20.1-0.00.7-0.7-0.50.10.30.8-0.10.50.2-0.20.40.6-0.10.5-0.60.7
Bone: final force1.93.19.3-3.0-3.12.52.81.8-1.81.5-1.1-1.7-1.9-0.1-1.7-0.71.60.0-1.71.4-1.5-0.30.6
Bone: final moment1.62.68.8-2.7-3.02.32.42.0-2.01.4-0.8-1.4-1.5-0.4-1.3-0.41.20.0-1.31.4-1.1-0.60.9
Food consumed during 24 hour testing period0.50.92.4-1.4-1.51.21.50.7-0.70.9-0.5-0.7-1.10.1-1.2-0.41.1-0.3-1.21.0-1.20.20.1
Glucose0.10.20.40.20.0-0.3-0.5-0.10.10.50.60.20.4-0.60.50.6-0.3-0.50.50.40.6-0.50.2
Heart weight0.00.10.3-0.1-0.40.20.30.3-0.30.50.20.2-0.3-0.2-0.10.20.1-0.2-0.10.5-0.1-0.20.3
Delay discount hyperbolic model param0.10.20.90.1-0.10.50.20.4-0.4-0.9-0.40.3-0.20.7-0.2-0.40.20.8-0.1-0.4-0.1-0.00.4
Intermittent access intake day 1-15 change0.20.82.50.60.8-1.3-0.6-1.51.51.00.60.5-0.4-0.0-0.50.2-0.1-1.6-0.50.6-0.71.3-1.4
Intermittent access intake escalation0.21.03.10.70.9-1.5-0.8-1.61.61.30.90.6-0.2-0.4-0.20.4-0.3-1.8-0.20.7-0.41.1-1.3
Intermittent access intake escalation 20.81.35.10.71.0-1.6-0.7-2.32.31.30.80.5-0.4-0.2-0.60.30.0-1.8-0.30.6-0.61.4-1.6
Intermitt. access day 1 inactive lever presses0.00.31.11.00.7-0.8-0.4-0.40.40.50.60.90.0-0.0-0.40.3-0.1-0.9-0.20.4-0.20.7-0.7
Intermitt. access day 15 inactive lever presses0.00.30.9-0.4-0.40.40.7-0.10.10.3-0.4-0.5-0.40.4-0.9-0.50.5-0.1-0.70.2-0.90.5-0.4
Intermitt. access escalation Index0.10.31.2-0.1-0.80.60.21.1-1.1-0.20.00.6-0.00.00.10.1-0.20.20.10.4-0.0-0.50.9
Intermittent access day 1 total infusions0.20.51.8-0.8-1.00.90.71.3-1.3-0.2-0.4-0.60.6-0.1-0.0-0.1-0.60.6-0.00.00.1-0.80.9
Intermittent access day 15 total infusions0.10.10.6-0.0-0.1-0.4-0.1-0.20.20.70.40.20.2-0.4-0.10.3-0.6-0.8-0.10.6-0.10.1-0.1
Intermittent access terminal intake (last 3 days)0.10.10.4-0.3-0.50.10.20.1-0.10.60.30.10.3-0.4-0.10.3-0.5-0.5-0.10.6-0.1-0.20.3
Intermittent access total infusions0.40.51.9-1.1-1.40.80.90.9-0.91.00.0-0.60.2-0.7-0.20.2-0.1-0.2-0.20.8-0.1-0.70.7
Intermittent access day 1 locomotion0.30.51.9-0.4-0.80.60.21.4-1.40.20.20.20.5-0.50.10.4-1.00.10.30.50.4-0.91.0
Intermittent access day 15 total locomotion0.31.12.50.8-0.3-0.5-0.80.6-0.60.71.31.31.6-1.10.91.4-1.5-0.90.91.11.0-1.21.1
Intermittent access total locomotion0.70.92.3-0.1-1.00.5-0.11.5-1.50.40.70.71.3-0.80.50.9-1.1-0.20.60.90.7-1.41.5
Intermittent access standard deviation0.31.43.8-1.2-1.10.61.5-0.70.71.9-0.2-0.9-1.7-0.1-1.8-0.40.3-1.3-1.71.3-1.71.0-0.8
Left kidney weight0.53.912.1-3.5-3.42.93.22.1-2.11.5-1.3-2.1-2.0-0.3-1.7-0.81.60.2-1.61.4-1.6-0.50.8
Right kidney weight0.64.215.6-3.5-3.93.23.22.4-2.41.7-1.1-1.8-1.6-0.7-1.3-0.41.40.3-1.21.7-1.2-1.21.6
Cocaine induced anxiety0.10.20.60.60.4-0.3-0.10.0-0.0-0.30.10.8-0.70.6-0.2-0.20.5-0.3-0.50.1-0.50.7-0.4
Post-drug Anxiety0.80.92.11.20.2-0.9-1.10.3-0.30.51.41.50.8-1.01.21.3-0.8-1.11.00.91.0-0.70.6
Baseline Anxiety0.71.23.9-0.3-0.7-0.3-0.60.4-0.41.71.2-0.01.3-2.01.01.5-0.9-1.01.21.21.2-1.51.0
Tail length0.21.23.3-1.8-1.80.90.61.5-1.51.70.2-1.10.1-1.60.20.6-0.2-0.50.31.20.3-1.20.9
Length with tail0.10.61.7-1.1-0.50.1-0.10.9-0.90.80.2-1.20.7-1.30.70.5-0.60.00.90.11.0-1.10.4
Length without tail0.10.61.80.51.3-1.4-0.9-1.11.1-0.10.5-0.20.5-0.60.90.5-0.5-0.21.1-0.71.0-0.1-0.6
Times rat made contact with spout2.02.35.2-1.6-0.81.02.0-0.50.50.8-1.2-1.5-2.21.1-2.3-1.42.0-0.3-2.30.3-2.31.7-1.4
Lifetime Intake0.60.72.5-1.5-1.61.11.21.0-1.01.0-0.2-0.90.2-0.7-0.40.10.2-0.1-0.30.8-0.2-0.80.8
Liver weight, left0.50.84.10.80.60.4-0.51.0-1.0-2.0-0.60.60.80.90.4-0.5-0.51.70.6-1.40.4-0.30.6
Liver weight, right0.50.94.00.10.80.60.0-0.10.1-2.0-1.3-0.5-0.01.4-0.2-1.20.22.0-0.1-1.9-0.20.4-0.2
Locomotor activity0.10.20.70.1-0.00.6-0.30.6-0.6-0.8-0.40.20.20.50.0-0.3-0.70.9-0.1-0.50.1-0.20.4
Locomotor testing distance0.10.20.6-0.1-0.50.8-0.00.7-0.7-0.3-0.20.20.10.1-0.0-0.1-0.60.5-0.10.00.1-0.40.6
Locomotor testing rearing0.10.41.20.40.20.4-0.40.9-0.9-1.1-0.30.40.40.30.5-0.1-0.61.10.5-0.80.6-0.60.7
Locomotion in novel chamber0.71.03.8-0.2-1.21.00.31.8-1.8-0.50.20.70.7-0.40.80.5-0.40.80.80.30.8-1.62.0
Locomotion in novel chamber post-restriction0.61.94.81.3-0.2-0.4-1.41.2-1.2-0.41.32.21.9-1.01.61.5-1.5-0.01.60.71.5-1.82.0
Fecal boli incidents, locomotor time 10.30.94.80.40.90.10.00.3-0.3-2.2-1.1-0.4-0.11.4-0.0-1.10.41.70.2-1.9-0.10.5-0.2
Change in fecal boli incidents, locomotor task2.02.16.3-0.6-1.4-0.3-0.60.8-0.82.11.60.71.5-2.51.61.9-1.5-1.11.11.81.0-2.11.7
Time >=10cm from walls, locomotor time 10.30.31.0-1.0-0.80.30.80.1-0.10.6-0.3-0.7-0.8-0.0-0.7-0.20.7-0.3-0.60.4-0.80.3-0.2
Bouts of movement, locomotor time 11.11.44.82.21.8-1.6-1.6-0.90.9-1.40.82.01.10.51.00.6-1.0-0.00.9-0.70.90.10.0
Total resting periods, locomotor time 11.31.54.72.22.1-1.7-1.7-1.21.2-1.60.61.71.10.61.10.3-1.00.21.0-1.10.80.3-0.2
Rest time, locomotor task time 10.60.92.80.11.7-1.3-0.6-1.71.7-0.6-0.4-0.7-0.00.60.0-0.60.10.1-0.2-1.3-0.61.3-1.6
Distance moved, locomotor task time 10.41.03.8-0.4-1.71.30.51.9-1.90.70.40.50.2-0.70.00.6-0.4-0.00.11.20.5-1.31.6
Vertical activity count, locomotor time 10.21.45.8-0.8-2.11.11.11.3-1.32.10.70.3-0.5-1.0-0.80.80.2-1.5-0.82.4-0.3-0.70.9
Time >=10cm from walls, locomotor time 20.41.23.2-1.8-1.31.21.7-0.10.11.0-0.8-1.7-1.50.0-1.3-0.71.5-0.2-1.20.4-1.40.5-0.5
Bouts of movement, locomotor time 20.72.57.2-0.50.21.61.21.1-1.1-2.7-2.3-0.9-0.72.6-1.4-2.21.12.6-1.1-2.1-0.71.1-0.4
Total resting periods, locomotor time 20.62.46.3-0.80.01.71.31.1-1.1-2.4-2.3-1.1-0.82.5-1.5-2.21.12.5-1.2-2.0-0.71.0-0.4
Rest time, locomotor task time 20.10.10.4-0.4-0.1-0.3-0.20.2-0.20.40.3-0.40.4-0.60.40.4-0.4-0.20.50.20.2-0.40.2
Distance moved, locomotor task time 20.50.71.8-0.5-0.40.41.0-0.70.71.20.1-0.3-1.10.1-1.3-0.21.0-1.1-1.31.0-0.70.9-0.8
Vertical activity count, locomotor time 20.40.94.6-0.1-0.7-0.10.3-0.30.32.11.10.3-0.2-1.0-0.70.90.1-2.1-0.62.0-0.20.1-0.2
Light reinforcement 10.20.81.90.80.20.0-0.91.0-1.0-0.90.30.61.3-0.21.00.5-1.40.81.1-0.41.1-1.11.1
Light reinforcement 20.20.61.40.5-0.20.2-0.51.1-1.1-0.60.30.80.9-0.30.90.5-0.90.60.8-0.10.9-1.11.2
Bone: marrow area1.12.65.9-2.1-1.52.42.01.7-1.7-0.6-2.1-1.7-1.61.4-1.8-1.81.41.5-1.9-0.6-1.80.6-0.1
Bone: maximum diameter1.02.15.3-2.3-2.12.22.21.8-1.80.3-1.4-1.3-1.50.5-1.5-1.11.20.8-1.50.4-1.40.00.4
Bone: maximum force1.42.88.4-2.9-2.82.32.61.6-1.61.6-1.0-1.7-1.9-0.2-1.6-0.71.4-0.1-1.71.4-1.6-0.10.4
Bone: maximum moment1.22.27.4-2.6-2.72.12.21.8-1.81.4-0.7-1.3-1.4-0.4-1.2-0.41.0-0.1-1.31.4-1.1-0.50.7
Mean time between licks in bursts0.00.31.00.50.60.0-0.0-0.20.2-1.0-0.30.9-0.31.0-0.3-0.50.40.5-0.3-0.6-0.30.6-0.2
Mean num. licks in bursts1.23.29.1-3.0-3.02.82.62.3-2.31.1-1.4-2.2-1.4-0.0-1.3-0.91.20.8-1.20.8-1.3-0.71.0
Cd content in liver3.84.39.21.70.0-0.7-2.22.0-2.0-0.61.62.22.9-1.52.72.0-3.00.52.70.22.7-2.82.6
Co content in liver1.82.15.90.5-0.5-1.2-0.9-0.40.42.42.11.20.7-2.31.12.0-1.1-2.31.02.21.1-1.10.6
Cu content in liver0.60.72.0-0.6-1.40.50.30.9-0.91.10.60.40.1-1.20.50.8-0.3-0.50.31.30.5-1.31.3
Fe content in liver1.01.22.90.7-0.1-1.1-0.8-0.60.61.21.71.40.7-1.51.11.6-0.8-1.61.01.41.1-0.90.7
K content in liver0.10.10.5-0.0-0.70.50.40.6-0.6-0.00.00.4-0.1-0.10.00.10.10.1-0.10.40.0-0.40.7
Mg content in liver0.40.41.4-0.3-0.10.80.60.8-0.8-1.0-0.9-0.3-0.50.9-0.3-0.80.61.2-0.4-0.8-0.30.10.2
Mn content in liver0.40.51.0-0.7-0.50.91.00.2-0.2-0.2-0.8-0.6-0.90.7-0.8-0.80.90.5-0.9-0.2-0.80.5-0.2
Na content in liver4.14.610.0-2.5-1.52.73.20.7-0.7-0.6-2.6-2.1-2.82.1-2.7-2.53.01.4-2.8-0.6-2.71.6-0.8
Rb content in liver6.07.012.92.10.0-2.0-2.71.0-1.01.13.23.32.9-3.13.63.5-2.9-1.33.51.73.6-3.42.9
Se content in liver0.30.31.2-0.4-0.30.30.8-0.30.30.2-0.3-0.2-1.10.4-0.8-0.41.1-0.3-0.90.3-0.80.6-0.5
Sr content in liver0.50.51.1-0.7-0.71.10.90.5-0.5-0.4-0.9-0.7-0.60.7-0.8-0.80.40.7-0.8-0.2-0.80.4-0.0
Zn content in liver1.41.75.2-1.3-1.32.11.32.3-2.3-0.9-1.5-0.7-0.81.0-0.8-1.20.51.8-0.9-0.6-0.8-0.20.8
Bone: minimum diameter1.32.56.0-2.4-1.72.22.21.2-1.2-0.1-1.9-2.0-2.01.1-1.8-1.71.51.2-1.9-0.3-1.80.6-0.2
Time in familiar zone, hab. session 11.51.73.51.20.1-1.3-1.3-0.30.31.21.91.71.4-1.61.31.7-1.3-1.71.21.51.2-0.90.6
Time in novel zone, hab. session 11.82.06.3-1.8-0.11.31.20.1-0.1-1.2-2.2-2.5-1.41.5-1.1-1.91.02.1-1.1-2.0-1.10.8-0.8
Total zone transitions, hab. session 10.91.35.6-1.8-2.41.41.21.1-1.11.70.2-0.9-0.0-1.3-0.30.5-0.0-0.7-0.31.7-0.3-1.11.1
Total locomotion distance, hab. session 12.02.811.5-2.5-3.42.41.62.3-2.32.0-0.2-1.30.1-1.5-0.20.4-0.3-0.2-0.32.0-0.3-1.81.9
Locomotion velocity, hab. session 11.82.59.8-2.0-3.12.31.32.6-2.61.5-0.1-0.70.3-1.3-0.00.5-0.40.1-0.11.8-0.1-1.92.2
Time in familiar zone, hab. session 20.20.20.7-0.4-0.80.30.30.8-0.80.70.20.1-0.0-0.4-0.10.20.0-0.4-0.30.7-0.3-0.20.3
Time in novel zone, hab. session 20.10.10.30.20.20.1-0.2-0.00.0-0.5-0.10.10.10.10.30.0-0.30.40.4-0.40.4-0.30.3
Total zone transitions, hab. session 20.81.14.5-1.6-2.11.40.91.2-1.21.1-0.0-1.00.3-1.0-0.10.4-0.4-0.2-0.01.2-0.0-1.31.3
Total locomotion distance, hab. session 21.21.56.1-1.8-2.51.51.21.4-1.41.80.1-1.20.2-1.3-0.20.5-0.2-0.6-0.21.7-0.2-1.31.2
Locomotion velocity, hab. session 21.21.77.0-2.1-2.61.91.41.5-1.51.7-0.2-1.3-0.0-1.0-0.50.2-0.0-0.3-0.51.6-0.5-1.11.2
Novel to familiar place preference ratio0.60.82.31.30.8-1.1-1.1-1.51.50.41.11.30.5-0.40.50.8-0.6-1.10.50.70.50.1-0.2
Novelty place preference0.71.03.11.30.8-1.3-1.0-1.81.80.71.21.20.5-0.50.40.9-0.5-1.40.40.80.40.3-0.4
Time in novel zone, NPP test0.70.91.91.30.7-1.2-1.2-1.41.40.61.31.30.7-0.60.61.0-0.9-1.20.60.80.6-0.1-0.0
Total zone transitions, NPP test0.50.73.2-1.5-1.81.21.10.9-0.91.0-0.2-1.0-0.1-0.6-0.40.10.1-0.2-0.41.0-0.4-0.70.8
Total locomotion distance, NPP test0.60.93.5-1.3-1.91.00.90.7-0.71.70.2-0.5-0.2-0.9-0.40.4-0.0-0.8-0.41.6-0.4-0.70.7
Locomotion velocity, NPP test0.50.72.8-1.3-1.70.81.10.5-0.51.70.2-0.6-0.2-0.9-0.40.40.3-0.8-0.41.5-0.4-0.60.6
Intraocular pressure0.20.41.0-0.7-0.20.70.6-0.00.0-0.4-1.0-1.0-0.50.6-0.3-0.80.71.0-0.4-0.7-0.50.3-0.2
Delta distance traveled before/after self-admin0.60.72.0-1.2-0.51.00.90.5-0.5-0.2-1.2-1.4-0.80.6-0.8-1.10.80.8-0.6-0.6-0.80.5-0.4
Delta ambulatory time before/after self-admin0.61.02.8-1.4-0.71.11.2-0.00.00.2-1.3-1.7-1.10.6-1.2-1.21.20.6-1.0-0.4-1.20.7-0.7
Parametrial fat weight1.94.413.1-1.6-3.52.11.33.6-3.61.00.6-0.00.8-2.01.21.5-0.40.21.32.01.3-3.43.6
Pavlov. Cond. lever latency3.44.310.10.9-0.3-1.9-1.8-0.80.82.92.91.52.0-3.22.02.9-2.1-3.01.92.61.9-1.70.8
Pavlov. Cond. magazine entry latency5.06.512.7-2.1-1.13.43.11.8-1.8-2.6-3.5-2.1-2.73.1-2.4-3.22.93.6-2.3-2.3-2.31.2-0.1
Pavlov. Cond. change in total contacts5.86.212.1-1.60.42.02.50.0-0.0-2.4-3.3-2.3-3.23.5-2.8-3.43.12.7-2.6-2.6-2.62.6-1.8
Pavlov. Cond. index score4.65.812.4-1.4-0.12.62.41.2-1.2-3.1-3.4-1.9-2.53.4-2.2-3.32.63.5-2.2-2.8-2.21.6-0.7
Pavlov. Cond. latency score3.84.810.4-1.3-0.32.42.31.2-1.2-2.8-3.1-1.7-2.23.1-2.0-2.92.43.2-1.9-2.5-2.01.4-0.5
Pavlov. Cond. lever contacts4.65.611.3-1.6-0.32.62.51.2-1.2-2.8-3.4-2.1-2.43.2-2.3-3.22.53.3-2.2-2.6-2.31.6-0.7
Pavlov. Cond. magazine entry number4.45.611.11.60.2-2.5-2.6-0.80.82.53.32.12.7-3.22.43.2-2.9-3.12.22.52.3-1.80.9
Pavlov. Cond. intertrial magazine entries2.83.36.01.70.3-1.7-2.1-0.40.41.12.42.22.1-2.22.22.4-2.3-1.72.11.52.1-1.71.3
Pavlov. Cond. lever-magazine prob. diff.5.16.313.2-1.6-0.32.92.61.4-1.4-3.1-3.6-2.0-2.63.5-2.4-3.42.73.6-2.3-2.8-2.41.6-0.6
Pavlov. Cond. response bias5.87.314.4-1.8-0.12.72.80.7-0.7-2.9-3.8-2.5-3.03.7-2.8-3.73.13.5-2.7-3.0-2.72.2-1.3
Pavlov. Cond. lever latency0.60.83.31.01.4-1.5-0.9-1.81.80.10.60.20.20.00.10.3-0.1-0.90.1-0.10.30.8-1.1
Pavlov. Cond. magazine entry latency0.50.72.10.61.4-0.5-0.2-0.90.9-1.3-0.70.1-0.31.2-0.3-0.90.40.8-0.3-1.5-0.51.2-1.1
Pavlov. Cond. change in total contacts0.71.83.90.7-0.70.1-0.91.6-1.60.11.01.61.6-1.31.71.3-1.70.11.70.61.5-2.02.0
Pavlov. Cond. index score0.10.20.60.1-0.10.50.00.8-0.8-0.7-0.30.50.20.30.2-0.2-0.20.80.2-0.5-0.0-0.30.5
Pavlov. Cond. latency score0.10.20.6-0.0-0.10.50.20.6-0.6-0.7-0.50.3-0.10.4-0.0-0.40.00.7-0.1-0.5-0.3-0.00.2
Pavlov. Cond. lever contacts0.60.83.5-1.0-1.31.60.91.9-1.9-0.4-0.8-0.2-0.30.2-0.1-0.40.21.1-0.1-0.1-0.4-0.71.1
Pavlov. Cond. magazine entry number0.60.82.6-1.6-1.61.21.20.9-0.91.1-0.3-1.2-0.7-0.4-0.8-0.20.6-0.3-0.80.9-0.6-0.30.4
Pavlov. Cond. intertrial magazine entries0.81.75.2-1.9-2.02.31.81.9-1.90.0-1.3-1.2-1.20.5-1.0-0.90.91.1-1.00.2-0.9-0.50.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.80.20.20.4-0.00.5-0.5-0.9-0.40.50.10.50.2-0.4-0.10.90.1-0.7-0.1-0.10.3
Pavlov. Cond. response bias0.30.31.5-0.0-0.40.80.21.2-1.2-0.7-0.40.40.10.20.3-0.2-0.11.00.3-0.40.0-0.50.8
Time in closed arm before self-admin0.00.10.2-0.2-0.50.10.10.3-0.30.30.20.20.0-0.2-0.00.2-0.2-0.30.00.5-0.1-0.20.3
Time in closed arm after self-admin0.30.40.60.40.3-0.8-0.6-0.70.70.60.70.40.7-0.80.60.7-0.7-0.70.50.40.6-0.3-0.0
Time in open arm before self-admin0.30.41.71.21.3-0.9-0.8-0.40.4-0.80.20.50.20.40.30.0-0.00.10.2-0.70.40.4-0.5
Time in open arm after self-admin1.41.53.4-1.3-1.11.61.60.6-0.60.3-1.2-1.0-1.91.0-1.8-1.31.40.3-1.80.2-1.91.0-0.5
Bone: periosteal estimation1.63.910.2-3.2-2.62.92.91.8-1.80.5-2.0-2.3-2.20.9-2.2-1.71.81.0-2.30.3-2.10.40.1
Bone: periosteal perimeter1.02.14.8-2.1-1.72.22.01.5-1.5-0.4-1.7-1.5-1.51.0-1.4-1.41.11.4-1.5-0.3-1.40.20.3
Bone: post-yield work1.22.17.8-1.7-2.22.61.32.8-2.8-0.4-1.1-0.7-0.20.1-0.3-0.6-0.01.7-0.20.0-0.3-1.31.8
Progressive ratio test 1 active lever presses0.30.51.7-0.9-0.60.80.71.3-1.3-0.8-0.7-0.40.00.6-0.6-0.5-0.00.8-0.5-0.3-0.3-0.10.4
Progressive ratio test 1 breakpoint0.30.51.6-0.8-0.50.70.61.3-1.3-0.9-0.7-0.40.00.7-0.6-0.6-0.00.9-0.5-0.4-0.3-0.10.3
Progressive ratio test 1 inactive lever presses0.10.31.1-0.00.00.30.20.9-0.9-1.1-0.50.20.30.9-0.5-0.6-0.30.6-0.4-0.4-0.40.40.0
Progressive ratio test 2 active lever presses0.20.30.9-0.50.10.20.10.8-0.8-0.9-0.5-0.40.60.40.1-0.40.30.90.1-0.80.2-0.10.1
Progressive ratio test 2 breakpoint0.20.30.9-0.40.10.10.00.8-0.8-1.0-0.5-0.40.70.40.2-0.30.20.90.2-0.80.3-0.20.2
Progressive ratio test 2 inactive lever presses0.10.31.3-0.5-0.50.60.51.1-1.1-0.3-0.4-0.30.40.2-0.4-0.30.40.5-0.1-0.1-0.2-0.10.3
Incentive Sensitization - Responses0.10.31.2-0.40.5-0.00.1-0.10.1-1.0-0.7-0.70.20.6-0.1-0.71.00.9-0.0-1.10.00.3-0.4
Incentive Sensitization - Breakpoint0.10.31.0-0.40.30.10.1-0.00.0-0.9-0.7-0.70.40.50.0-0.50.90.90.0-1.00.10.1-0.2
Sum of active levers in priming session hrs 5-61.31.27.21.21.00.1-0.70.8-0.8-2.7-0.60.80.91.30.7-0.5-0.41.90.8-1.70.8-0.40.7
Progressive ratio0.30.92.00.3-0.5-0.1-0.61.3-1.30.40.80.71.2-1.21.21.0-0.8-0.21.20.71.1-1.41.3
Food seeking constrained by brief footshock0.60.71.61.20.9-1.3-1.0-0.90.90.21.01.20.4-0.60.90.9-1.1-0.80.90.20.9-0.2-0.1
Seeking ratio, punishment vs. effort0.51.12.7-0.70.40.41.1-1.11.1-0.6-1.1-0.9-1.61.3-1.3-1.21.00.5-1.2-0.9-1.11.4-1.2
Retroperitoneal fat weight1.46.321.4-1.2-3.32.40.74.4-4.4-0.20.40.61.5-2.02.21.5-1.11.72.21.02.1-4.44.6
Reaction time number correct0.10.51.60.81.0-0.5-1.1-0.50.5-1.3-0.10.41.00.40.7-0.0-1.00.80.7-1.10.6-0.10.0
Reaction time mean minus median0.00.20.70.1-0.60.10.10.4-0.40.60.40.60.1-0.4-0.10.3-0.3-0.5-0.10.8-0.2-0.20.4
Reaction time mean minus median AUC0.10.82.00.9-0.3-0.4-0.90.6-0.60.20.91.41.1-0.81.01.0-1.4-0.41.00.70.9-1.11.2
Reaction time num false alarms0.50.82.51.01.1-1.2-0.7-1.61.60.60.70.7-0.1-0.0-0.30.2-0.0-1.3-0.40.4-0.31.2-1.3
Reaction time num false alarms AUC0.20.41.30.71.0-0.7-0.5-1.21.20.00.10.3-0.30.4-0.4-0.30.2-0.5-0.5-0.2-0.31.1-1.1
Reaction time trials correct on left0.10.51.60.81.0-0.5-1.1-0.50.5-1.3-0.10.41.00.40.7-0.0-1.00.80.7-1.10.6-0.10.0
Reaction time trials on left0.20.51.80.81.0-0.5-1.1-0.50.5-1.3-0.10.40.90.40.7-0.0-1.00.80.8-1.10.6-0.20.1
Reaction time mean0.10.31.5-0.1-0.70.40.31.2-1.20.30.00.40.0-0.30.10.20.10.10.10.40.0-0.50.7
Reaction time mean AUC0.10.10.9-0.0-0.30.30.21.0-1.0-0.2-0.20.2-0.10.10.1-0.10.20.40.1-0.10.0-0.30.5
Median of all reaction times0.20.32.0-0.3-0.60.60.51.4-1.4-0.1-0.20.1-0.1-0.00.1-0.10.30.5-0.00.0-0.0-0.40.6
Reaction time omissions0.30.52.80.30.40.4-0.10.5-0.5-1.7-0.80.0-0.10.90.2-0.7-0.01.50.1-1.40.1-0.00.3
Reaction time false alarm rate0.40.61.80.20.5-0.50.2-1.11.10.80.1-0.1-0.90.3-0.9-0.30.8-1.0-1.00.4-0.81.3-1.3
Reaction time premature initiation rate1.01.53.4-1.8-0.91.11.7-0.50.50.9-1.2-1.9-1.40.5-1.6-1.21.50.1-1.60.0-1.71.1-1.0
Reaction time premature initiations0.31.02.7-1.3-0.10.71.0-0.90.90.0-1.3-1.6-0.90.8-1.1-1.30.90.6-1.1-0.7-1.31.1-1.1
Std. dev. reaction times0.10.30.9-0.0-0.80.30.00.9-0.90.50.40.50.3-0.60.40.5-0.4-0.20.30.70.2-0.70.9
Reaction time trials completed0.20.51.80.81.0-0.5-1.1-0.50.5-1.3-0.10.40.90.40.7-0.0-1.00.80.8-1.10.6-0.20.1
Reaction time trials AUC0.10.41.30.60.8-0.3-0.9-0.40.4-1.1-0.10.30.90.30.7-0.0-0.90.80.7-1.00.6-0.20.1
Run reversals in cocaine runway, females2.52.86.8-2.5-1.91.72.6-0.10.12.0-1.2-2.1-2.20.1-2.2-1.11.8-0.6-2.21.0-2.11.0-0.9
Run reversals in cocaine runway, males0.30.41.10.70.9-1.0-0.8-0.90.90.20.50.40.5-0.20.20.3-0.9-0.70.20.00.20.4-0.6
Latency to leave start box in cocaine runway1.01.43.10.3-0.4-0.4-1.10.8-0.80.41.20.91.7-1.31.61.4-1.8-0.41.50.71.5-1.71.5
Latency to leave start box in cocaine runway, F0.20.30.80.10.2-0.0-0.60.1-0.1-0.9-0.00.20.60.10.70.1-0.90.70.7-0.60.7-0.50.5
Latency to leave start box in cocaine runway, M2.22.14.00.4-0.8-0.6-1.21.0-1.01.21.71.11.9-2.01.61.9-1.5-1.21.61.61.6-1.91.6
Std. dev. time between licks in bursts0.30.61.70.2-0.31.10.60.8-0.8-1.3-0.90.5-0.61.3-0.7-0.80.51.2-0.7-0.6-0.70.20.5
Total sessions with >9 infusions2.32.99.4-3.1-2.72.72.42.5-2.50.7-1.3-2.1-0.4-0.2-1.2-0.71.01.1-0.80.4-0.8-1.01.2
Short access day 1 total inactive lever presses0.20.31.0-1.0-0.60.70.71.0-1.00.3-0.6-1.00.10.1-0.6-0.40.20.2-0.6-0.0-0.40.1-0.1
Short access day 10 total inactive lever presses0.10.72.91.21.7-1.6-1.0-1.11.1-0.30.20.40.30.40.0-0.1-0.0-0.5-0.0-0.6-0.11.2-1.4
Short access day 1 total infusions0.40.94.0-2.0-1.21.21.11.2-1.20.9-0.8-1.8-0.3-0.4-0.7-0.50.80.4-0.40.0-0.6-0.2-0.0
Short access day 10 total infusions0.91.54.6-2.1-1.71.81.71.9-1.90.1-1.3-1.8-0.40.3-1.1-0.80.50.9-0.8-0.0-0.8-0.40.5
Short access total infusions1.21.76.2-2.5-2.32.01.91.7-1.70.9-0.9-1.8-0.3-0.5-0.8-0.40.60.6-0.70.6-0.6-0.90.9
Short access day 1 locomotion0.30.42.1-1.2-0.70.40.70.5-0.51.40.1-0.9-0.3-0.7-0.80.10.5-0.6-0.30.7-0.3-0.1-0.2
Short access day 10 total locomotion0.52.26.2-2.0-2.02.52.11.9-1.9-0.2-1.4-1.0-1.21.0-2.1-1.20.60.9-1.90.3-1.40.20.5
Short access total locomotion1.42.16.7-2.0-2.62.21.52.6-2.61.2-0.2-0.70.2-0.9-0.70.3-0.30.2-0.31.3-0.0-1.61.8
One hour access (0.3 mA shock)0.30.41.00.2-0.40.2-0.11.0-1.0-0.9-0.00.61.00.20.60.1-0.60.60.5-0.10.4-0.71.0
Compulsive drug intake0.30.42.10.40.20.6-0.30.7-0.7-1.5-0.40.40.60.40.7-0.20.11.30.4-0.80.6-0.50.7
One hour access (shock baseline)0.10.31.20.5-0.2-0.5-0.4-0.00.00.50.80.80.6-0.50.20.7-1.1-0.80.50.80.3-0.40.4
Social response proportion0.60.82.70.7-0.10.1-0.80.7-0.7-0.80.40.91.3-0.31.10.6-1.60.61.0-0.11.1-1.31.4
Social responses0.60.72.41.20.7-0.2-1.00.7-0.7-1.60.11.10.90.50.80.1-1.50.90.7-0.80.8-0.40.7
Social time0.60.93.31.20.9-1.0-1.4-0.10.1-0.40.80.91.2-0.51.30.8-1.8-0.01.1-0.31.3-0.70.4
Soleus weight0.82.410.3-2.7-3.21.92.01.0-1.02.6-0.0-1.1-0.7-1.4-0.80.30.6-0.9-0.92.3-0.9-1.11.1
Bone: stiffness1.12.05.7-2.4-2.21.52.20.6-0.61.9-0.5-1.4-1.6-0.4-1.6-0.41.4-0.9-1.61.6-1.40.2-0.1
Tibialis anterior weight2.58.729.4-5.4-5.04.34.62.5-2.52.8-1.9-3.5-2.6-0.4-2.8-1.32.6-0.0-2.92.2-2.7-0.40.8
Time to tail flick, vehicle, before self-admin0.10.10.4-0.1-0.40.30.2-0.60.60.50.10.20.1-0.1-0.30.1-0.1-0.3-0.30.6-0.2-0.00.2
Time to tail flick, vehicle, after self-admin0.61.34.01.62.0-1.4-1.6-0.80.8-1.90.10.70.90.71.1-0.0-1.20.81.1-1.71.00.2-0.4
Time to tail flick, test, before self-admin0.30.41.20.10.20.10.2-0.50.50.1-0.4-0.0-0.70.7-1.0-0.70.3-0.1-0.9-0.1-1.11.1-0.9
Time to tail flick, test, after self-admin2.22.45.30.11.0-0.00.9-1.81.8-1.2-1.4-0.6-2.02.3-1.9-1.81.50.5-1.9-1.2-1.82.3-1.8
Delta time to tail flick, vehicle, before/after SA0.30.31.20.50.5-0.3-0.50.2-0.2-1.1-0.10.10.50.10.80.1-0.60.80.8-0.80.7-0.40.4
Delta time to tail flick, test, before/after SA0.30.40.9-0.5-0.20.40.8-0.20.2-0.6-0.7-0.6-0.90.8-0.7-0.71.00.4-0.8-0.3-0.60.5-0.2
Tibia length0.30.81.90.4-0.5-0.3-0.60.5-0.51.11.10.90.8-1.20.61.1-1.4-1.00.71.20.8-0.90.8
Ambulatory time before self-admin0.30.83.8-0.2-0.4-0.9-0.0-0.00.01.91.40.50.1-1.40.31.20.2-1.90.11.60.2-0.3-0.0
Ambulatory time after self-admin1.11.74.3-2.0-1.30.71.7-0.10.12.1-0.4-1.6-1.6-0.4-1.5-0.42.0-1.1-1.41.2-1.50.8-0.9
Bone: tissue strength0.20.20.6-0.5-0.1-0.00.4-0.00.00.5-0.1-0.4-0.80.0-0.5-0.20.5-0.4-0.50.2-0.60.5-0.5
Total heroin consumption0.70.83.30.60.6-0.1-0.90.9-0.9-1.8-0.20.51.10.50.90.0-0.81.41.0-1.21.1-0.80.8
Bone: trabecular number0.20.51.7-1.1-1.30.80.90.6-0.61.0-0.1-0.7-0.5-0.5-0.40.10.3-0.4-0.50.9-0.5-0.30.4
Bone: trabecular spacing0.71.05.11.01.3-0.1-0.3-0.20.2-2.3-0.90.4-0.11.7-0.1-1.00.31.6-0.1-1.9-0.00.7-0.4
Bone: trabecular thickness2.53.47.5-0.9-2.60.70.12.0-2.02.41.60.61.4-2.71.32.1-1.4-1.31.32.61.3-2.72.5
Bone: trabecular tissue density0.10.20.80.2-0.2-0.4-0.3-0.30.30.70.60.50.1-0.50.10.6-0.3-0.90.20.80.2-0.10.1
Water consumed over 24 hours1.32.67.3-0.21.3-0.80.5-2.62.60.2-0.8-1.1-1.71.4-1.8-1.41.6-0.6-1.8-0.7-1.82.6-2.7
Number of responses in last shaping day0.30.41.3-0.90.00.30.30.7-0.70.0-0.8-1.2-0.30.3-0.6-0.80.40.5-0.5-0.6-0.60.6-0.7