Hub : Genes

Iqck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Iqck 0.38 0.11 0.0e+00 0.22 0.26 0.26 0.27 1.4e-24 2.4e-28 6.0e-29 8.7e-30
2 Adipose isoform ratio XM_063283526.1 0.14 0.06 3.7e-13 0.08 0.08 0.07 0.08 3.3e-09 2.0e-09 8.2e-08 6.6e-09
3 OFC gene expression Iqck 0.28 0.14 4.1e-03 0.05 0.04 0.02 0.05 2.6e-02 4.4e-02 1.3e-01 3.0e-02
4 NAcc intron excision ratio chr1_182630887_182648437 0.03 0.02 2.1e-04 0.02 0.02 0.02 0.02 9.6e-04 9.7e-04 2.6e-04 5.6e-04
5 Brain alternative polyA NM_001401714.1 0.06 0.04 2.9e-04 0.05 0.03 0.04 0.04 1.1e-05 6.4e-04 1.8e-04 5.9e-05
6 Brain alternative polyA XM_039101165.2 0.07 0.04 2.0e-04 0.06 0.04 0.04 0.05 6.6e-06 3.2e-04 1.3e-04 3.5e-05
7 Adipose alternative TSS XM_063283495.1 0.04 0.04 1.6e-03 0.02 0.02 0.02 0.02 6.1e-03 2.2e-03 4.9e-03 1.2e-03
8 LHb gene expression Iqck 0.39 0.16 3.3e-04 0.02 0.09 0.05 0.06 1.2e-01 3.5e-03 2.7e-02 1.9e-02
9 Adipose alternative TSS XM_039101167.2 0.03 0.02 3.0e-03 0.01 0 0 0.01 2.2e-02 9.2e-02 1.6e-01 6.0e-02
10 NAcc gene expression Iqck 0.1 0.05 1.1e-06 0.04 0.05 0.05 0.06 3.6e-07 5.5e-08 1.1e-07 4.6e-09
11 PL gene expression Iqck 0.08 0.05 4.9e-05 0.02 0.05 0.06 0.05 3.8e-03 3.1e-06 4.8e-07 2.6e-06
12 NAcc isoform ratio NM_001401714.1 0.03 0.02 7.6e-03 0.01 0 0.01 0.01 2.1e-03 1.3e-01 8.2e-03 1.5e-02
13 Brain gene expression Iqck 0.13 0.06 7.6e-08 0.08 0.09 0.08 0.09 1.0e-07 1.1e-08 3.5e-08 1.3e-08
14 PL intron excision ratio chr1_182630887_182648437 0.02 0.02 9.0e-03 0.01 0.01 0.01 0 1.3e-02 6.2e-02 2.2e-02 7.8e-02
15 PL isoform ratio XM_063283526.1 0.06 0.04 1.8e-03 0.02 0.02 0.01 0.01 6.1e-03 1.8e-03 1.0e-02 2.1e-02
16 Brain intron excision ratio chr1_182648510_182652112 0.04 0.02 5.1e-03 0.02 0.02 0.01 0.02 3.2e-03 4.4e-03 4.7e-02 1.1e-02
17 BLA gene expression Iqck 0.18 0.08 2.3e-06 0.06 0.12 0.08 0.11 4.8e-04 8.4e-07 4.8e-05 1.7e-06
18 Adipose alternative TSS XM_063283495.1 0.13 0.14 3.2e-05 0.03 0.03 0.03 0.04 3.1e-04 4.4e-04 3.3e-04 8.0e-05
19 PL intron excision ratio chr1_182648510_182652112 0.07 0.04 1.1e-04 0.02 0.03 0.03 0.03 5.3e-03 3.1e-04 3.5e-04 8.3e-04
20 IC gene expression Iqck 0.12 0.07 3.3e-03 0.02 0.05 0.03 0.05 5.2e-02 3.1e-03 1.5e-02 5.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.40.72.8-1.3-1.7-1.2-0.8-1.21.21.0-0.10.7-0.20.70.20.20.1-0.10.31.0-0.3-0.80.9
Area under the delay curve0.30.41.20.20.40.90.50.6-0.61.10.80.00.51.0-0.50.70.5-1.1-0.40.50.4-0.1-0.4
BMI with tail1.75.818.3-3.4-3.9-4.3-3.6-2.82.80.1-2.21.7-2.4-1.02.2-1.6-2.21.72.30.8-2.2-0.61.7
BMI without tail2.47.223.8-4.1-4.9-4.6-3.6-4.14.11.2-1.82.1-1.70.21.6-1.0-1.71.41.81.5-1.6-1.62.5
Body weight1.04.413.6-3.5-3.7-3.5-2.8-3.23.20.8-1.62.1-1.30.21.1-0.9-1.11.31.20.8-1.0-1.41.8
Weight adjusted by age0.91.34.9-0.2-0.1-1.3-0.5-1.41.4-2.2-1.50.3-0.5-1.80.6-1.3-0.92.10.6-1.4-0.50.30.4
Bone surface0.61.13.1-1.8-1.3-1.4-1.4-1.01.00.4-1.01.5-1.2-0.21.1-0.8-0.90.41.10.2-1.20.3-0.1
Bone volume0.71.23.9-2.0-2.0-1.7-1.6-1.31.30.9-0.71.3-0.90.20.9-0.4-0.70.11.00.8-1.0-0.30.5
Breakpoint value in progressive ratio session0.81.02.21.31.40.91.40.7-0.7-1.50.2-0.71.4-0.3-1.20.21.00.9-1.2-1.21.3-0.40.2
Number of licking bursts1.72.78.72.42.82.71.83.0-3.0-0.31.1-1.60.3-0.4-0.10.30.2-1.40.0-0.40.11.7-2.0
Context. condit. distance diff. score0.20.30.70.60.60.30.7-0.20.2-0.80.1-0.40.6-0.2-0.50.10.80.5-0.8-0.60.8-0.30.2
Locomotion velocity, session 10.20.20.8-0.2-0.10.3-0.00.7-0.70.80.30.30.10.40.30.20.1-0.90.10.6-0.10.3-0.5
Locomotion distance, session 10.40.51.5-0.9-1.2-1.1-0.6-1.21.20.2-0.40.70.40.20.0-0.00.30.5-0.10.30.1-0.80.9
Locomotion velocity, session 20.20.31.10.10.20.80.20.7-0.70.90.60.20.20.6-0.10.50.1-1.0-0.10.60.10.1-0.4
Locomotion distance, session 20.60.93.4-1.8-1.7-1.4-1.3-0.70.70.9-0.71.5-0.60.20.9-0.4-0.40.00.80.7-0.8-0.20.3
Locomotion velocity, session 30.10.20.9-0.9-0.6-0.5-0.5-0.30.30.2-0.40.9-0.10.00.2-0.20.10.30.2-0.0-0.2-0.20.1
Locomotion distance, session 31.11.22.1-1.00.2-0.5-0.80.9-0.9-0.3-1.31.5-1.2-1.21.5-1.4-0.90.51.5-0.8-1.41.4-1.3
Stereotopy head waving bouts, day 30.50.61.51.00.60.81.0-0.00.0-0.10.8-0.91.10.6-1.20.91.0-0.2-1.2-0.01.2-0.80.5
Stereotopy head waving duration, day 30.50.61.40.60.10.50.7-0.80.80.10.7-0.71.10.8-1.20.90.8-0.1-1.20.21.2-1.00.8
Locomotion velocity, session 72.32.56.7-2.2-0.5-1.3-2.20.1-0.1-0.4-2.02.6-2.1-1.41.9-1.9-2.11.21.7-1.1-1.51.2-1.2
Locomotion distance, session 71.11.43.2-0.70.6-0.1-1.11.1-1.1-0.2-1.11.3-1.8-1.21.4-1.3-1.80.31.2-0.8-1.11.6-1.6
Stereotopy head waving bouts, day 70.30.41.2-0.4-0.5-0.20.3-1.01.00.10.10.41.10.5-0.60.41.10.2-0.40.10.5-0.90.7
Stereotopy head waving duration, day 70.91.13.9-1.5-1.6-1.5-0.9-2.02.0-0.2-0.81.10.20.00.2-0.30.20.90.40.1-0.3-0.91.1
Locomotion velocity, session 80.10.10.7-0.2-0.20.10.40.2-0.20.50.20.20.70.4-0.20.30.8-0.3-0.10.30.1-0.30.1
Locomotion distance, session 80.10.10.5-0.6-0.5-0.6-0.3-0.30.3-0.1-0.40.7-0.0-0.20.3-0.20.20.3-0.1-0.00.1-0.20.3
Degree of sensitization distance0.91.01.90.9-0.10.60.6-0.60.60.71.3-1.30.61.3-1.31.40.4-0.7-1.30.91.4-1.21.0
Degree of sensitization stereotypy0.60.72.6-1.6-1.4-1.1-0.9-1.11.10.3-0.71.4-0.00.10.5-0.40.10.40.50.2-0.5-0.40.4
Conditioned locomotion0.91.12.30.11.30.3-0.31.2-1.2-1.2-1.00.8-1.0-1.40.8-1.2-1.00.80.8-1.5-0.71.4-1.4
Cocaine response after cond. corrected0.10.10.50.50.50.60.20.7-0.70.10.3-0.4-0.20.1-0.10.20.1-0.4-0.00.10.00.3-0.3
Cocaine response after cond. not corrected0.10.10.4-0.4-0.2-0.2-0.50.1-0.10.2-0.30.4-0.6-0.20.4-0.4-0.4-0.00.5-0.0-0.50.4-0.3
Cocaine response before conditioning1.41.75.2-2.3-1.3-1.6-1.8-0.70.70.4-1.52.0-1.3-0.61.5-1.3-1.50.61.5-0.1-1.60.6-0.5
Saline control response0.30.40.90.80.10.40.7-0.30.3-0.00.7-0.60.90.6-0.90.70.8-0.1-0.80.21.0-0.70.7
Bone: connectivity density0.40.61.8-1.1-1.1-1.3-0.9-1.11.1-0.1-0.80.9-0.5-0.20.5-0.5-0.30.70.60.0-0.6-0.30.5
Bone: cortical apparent density0.50.72.01.21.21.41.21.2-1.20.30.9-0.80.40.3-0.40.60.6-1.0-0.60.20.50.5-0.7
Bone: cortical area1.21.96.5-2.6-2.3-1.9-2.1-1.21.21.4-0.81.5-1.50.41.2-0.5-1.2-0.11.31.1-1.1-0.20.3
Bone: cortical porosity0.60.61.8-1.0-0.9-1.3-0.8-1.11.1-0.7-1.00.8-0.4-0.50.1-0.6-0.41.40.3-0.6-0.3-0.50.8
Bone: cortical porosity0.50.52.2-0.6-0.4-0.9-0.4-0.90.9-1.0-0.80.6-0.1-0.4-0.3-0.4-0.01.5-0.1-0.90.2-0.70.8
Bone: cortical thickness0.71.15.3-1.5-1.7-0.4-1.0-0.20.22.30.60.6-0.71.40.30.7-0.5-1.50.31.9-0.2-0.50.3
Bone: cortical thickness1.21.46.7-0.6-1.00.6-0.10.9-0.92.61.40.00.31.9-0.21.30.1-2.2-0.22.20.2-0.50.1
Bone: cortical tissue density0.50.71.91.21.21.41.21.2-1.20.20.9-0.80.40.3-0.40.60.6-0.9-0.70.20.50.4-0.7
Condit. Reinf. active minus inactive responses0.20.20.60.40.2-0.00.5-0.30.3-0.50.1-0.20.30.0-0.60.20.70.5-0.7-0.40.7-0.60.5
Condit. Reinf. active-inactive response ratio0.30.31.30.10.2-0.50.1-0.70.7-1.0-0.50.3-0.0-0.6-0.2-0.40.31.1-0.3-0.90.3-0.30.4
Condit. Reinf. active responses0.20.20.50.60.10.20.4-0.00.0-0.20.5-0.60.00.2-0.60.50.50.0-0.70.10.7-0.60.6
Condit. Reinf. inactive responses0.10.20.60.4-0.20.20.10.3-0.30.30.6-0.8-0.10.5-0.30.60.1-0.5-0.30.70.3-0.40.5
Incentive salience index mean0.20.30.8-0.20.1-0.6-0.5-0.10.1-0.8-0.70.5-0.9-0.90.5-0.7-0.40.80.4-0.7-0.40.4-0.1
Condit. Reinf. lever presses0.70.92.5-0.20.3-0.6-0.90.3-0.3-1.3-1.20.6-1.3-1.61.0-1.3-1.11.11.0-1.1-1.01.0-0.6
Condit. Reinf. active minus inactive responses1.01.34.70.2-1.3-1.20.0-2.02.0-0.50.1-0.80.90.4-0.70.50.80.9-0.90.40.8-1.82.2
Condit. Reinf. active-inactive response ratio1.11.33.90.9-0.6-0.50.6-1.51.5-0.60.6-1.51.20.5-1.20.91.10.6-1.40.31.2-1.72.0
Condit. Reinf. active responses0.50.73.0-0.2-1.1-1.3-0.2-1.71.7-0.5-0.3-0.30.4-0.0-0.20.10.51.0-0.40.10.2-1.21.5
Condit. Reinf. inactive responses0.91.22.6-1.6-0.8-1.2-1.4-0.40.4-0.0-1.41.6-1.3-0.81.3-1.3-1.10.71.4-0.4-1.50.7-0.6
Condit. Reinf. lever presses0.81.14.5-1.0-1.6-1.9-0.8-2.12.1-0.4-0.70.20.1-0.20.2-0.30.21.20.20.1-0.2-1.01.5
Condit. Reinf. lever reinforcers received0.50.72.70.1-0.8-1.00.0-1.61.6-0.8-0.2-0.50.5-0.1-0.50.10.61.1-0.6-0.20.4-1.11.5
Conditioned reinforcement - actives0.40.63.4-0.2-0.40.30.20.1-0.11.90.90.20.91.5-0.31.00.4-1.2-0.41.00.4-0.60.1
Conditioned reinforcement - inactives0.60.82.81.00.61.30.90.6-0.61.41.3-1.00.91.0-0.21.00.6-1.7-0.51.00.20.2-0.4
Conditioned locomotion0.10.10.30.10.20.50.20.0-0.00.60.40.00.50.4-0.00.30.1-0.6-0.20.30.10.1-0.3
Patch foraging indifference point 0 sec0.81.54.40.1-1.1-0.50.5-1.51.50.50.9-0.61.61.3-1.31.31.7-0.0-1.20.91.6-2.11.9
Patch foraging indifference point AUC0.40.52.5-0.3-1.1-0.5-0.2-0.70.71.30.7-0.50.10.80.30.70.1-1.10.21.6-0.1-0.40.6
Delay disc. indifference point, 0s delay0.91.02.3-1.1-0.6-0.4-1.20.8-0.81.5-0.31.3-0.80.11.4-0.5-1.0-1.01.20.8-1.11.1-1.2
Delay disc. indifference point, 16s delay2.62.96.52.52.02.42.51.3-1.30.01.8-1.72.11.2-2.11.72.0-0.9-2.0-0.12.0-0.70.1
Delay disc. indifference point, 2s delay1.82.05.6-2.4-2.0-1.8-2.4-0.60.61.4-1.11.9-1.50.01.6-0.9-1.5-0.11.60.9-1.60.4-0.2
Delay disc. indifference point, 24s delay1.51.65.01.72.02.22.11.5-1.5-0.21.1-1.11.10.5-1.30.81.3-0.8-1.2-0.50.90.3-0.7
Delay disc. indifference point, 4s delay0.80.84.2-0.3-0.40.70.20.7-0.72.01.10.00.31.6-0.31.00.3-1.8-0.31.50.1-0.2-0.2
Delay disc. indifference point, 8s delay0.20.21.1-0.50.10.4-0.20.4-0.41.00.20.8-0.40.50.20.1-0.4-0.80.40.3-0.30.4-0.8
Indifference point function ln k0.00.10.4-0.5-0.5-0.2-0.60.1-0.10.2-0.20.3-0.30.2-0.0-0.0-0.50.00.00.1-0.1-0.20.2
Indifference point function log k0.00.10.4-0.5-0.5-0.2-0.60.1-0.10.2-0.20.3-0.30.2-0.0-0.0-0.50.00.00.1-0.1-0.20.2
Patch foraging total patch changes 0 sec1.01.95.50.1-1.2-0.60.5-1.81.80.51.0-0.81.71.4-1.41.41.80.0-1.31.01.8-2.32.2
Patch foraging total patch changes 12 sec0.20.20.9-0.0-0.5-0.70.0-1.01.0-0.1-0.0-0.10.4-0.10.00.10.60.40.00.20.3-0.60.7
Patch foraging total patch changes 18 sec0.50.71.80.5-0.30.30.8-0.50.50.91.1-0.81.01.0-0.61.11.3-0.9-0.51.10.9-0.80.7
Patch foraging total patch changes 24 sec0.61.02.5-0.3-1.2-0.60.2-1.61.60.90.7-0.10.91.1-0.61.01.1-0.3-0.61.10.9-1.51.4
Patch foraging total patch changes 6 sec3.45.19.21.6-0.60.92.2-0.80.81.52.8-2.43.02.7-2.53.03.0-1.7-2.52.22.8-2.82.4
Patch foraging time to switch 0 sec1.12.37.01.02.51.00.51.5-1.5-2.3-1.30.7-0.6-2.20.6-1.6-0.51.40.6-2.6-0.62.0-2.0
Patch foraging water rate 0 sec0.10.20.7-0.6-0.8-0.6-0.5-0.80.80.1-0.1-0.1-0.10.3-0.10.1-0.20.2-0.10.4-0.0-0.50.6
Patch foraging water rate 12 sec0.71.53.7-0.8-1.7-0.6-0.2-1.51.51.40.8-0.20.81.9-1.11.20.8-0.5-1.11.40.9-1.91.7
Patch foraging water rate 18 sec0.40.62.1-0.4-0.9-0.5-0.1-1.11.10.10.3-0.20.50.9-1.00.60.50.4-1.00.30.8-1.41.3
Patch foraging water rate 24 sec0.30.52.2-0.9-1.0-0.1-0.6-0.30.31.50.50.30.11.2-0.20.6-0.3-0.9-0.21.10.1-0.50.3
Patch foraging water rate 6 sec0.91.33.40.6-0.60.70.6-0.40.41.51.7-1.50.81.7-0.91.61.0-1.7-0.91.80.9-1.00.9
Seeking ratio, delayed vs. immediate footshock0.00.10.1-0.1-0.4-0.1-0.3-0.30.30.10.1-0.0-0.10.10.00.2-0.3-0.10.00.30.3-0.40.4
Distance traveled before self-admin0.30.41.8-0.7-0.60.2-0.5-0.10.11.30.60.0-0.40.80.20.5-0.6-1.30.41.2-0.3-0.0-0.1
Distance traveled after self-admin1.31.64.0-2.0-1.3-0.9-1.7-0.20.21.7-0.61.5-1.60.11.6-0.6-1.8-0.91.61.0-1.60.9-0.8
Extensor digitorum longus weight2.811.129.9-5.5-3.6-4.2-4.9-1.31.31.5-3.44.4-3.9-1.64.3-3.1-3.90.84.30.5-3.91.9-1.3
Bone: elastic displacement1.11.32.21.10.31.31.40.2-0.20.81.5-1.41.31.3-1.51.51.5-1.0-1.10.81.2-1.00.7
Bone: elastic work0.20.21.0-0.6-0.9-0.1-0.4-0.30.31.00.30.1-0.30.6-0.10.40.1-0.50.20.8-0.1-0.50.4
Bone: endosteal estimation1.32.96.6-2.2-1.6-2.6-2.2-1.81.8-0.6-2.21.9-1.7-1.51.9-1.9-1.51.62.0-0.6-1.90.7-0.1
Bone: endosteal perimeter1.32.74.7-1.9-0.9-1.9-2.1-0.60.6-0.7-2.11.7-2.0-1.72.1-2.1-1.71.32.2-0.8-2.11.3-0.8
Epididymis fat weight0.51.65.5-1.4-2.3-2.0-1.3-2.32.30.5-0.40.2-0.40.60.10.1-0.10.70.00.9-0.2-1.41.8
Delta time in closed arm before/after self-admin2.01.83.5-0.90.4-0.7-1.10.8-0.8-0.9-1.81.5-1.5-1.71.6-1.9-1.41.21.7-1.3-1.61.7-1.4
Delta time in open arm before/after self-admin0.60.62.5-0.9-1.6-1.3-0.8-1.11.10.8-0.0-0.0-0.10.40.20.20.1-0.00.11.0-0.2-0.81.1
Diff in mean of infusions in LGA sessions1.51.93.91.2-0.40.61.1-0.90.90.31.6-2.01.81.3-1.61.81.5-0.7-1.51.21.6-1.71.8
Delay discount exponential model param0.30.30.9-0.2-0.5-0.9-0.5-0.70.7-1.0-0.7-0.1-0.4-0.80.4-0.6-0.41.00.3-0.4-0.3-0.10.5
Extinction: sum of active levers before priming0.30.31.41.00.90.30.70.5-0.5-1.2-0.2-0.70.4-0.8-0.1-0.30.40.6-0.1-0.80.10.4-0.2
Active lever presses in extinction session 60.20.20.6-0.0-0.2-0.10.0-0.70.7-0.50.1-0.30.80.1-0.50.20.20.4-0.6-0.10.5-0.60.7
Bone: final force1.93.19.3-3.0-3.1-2.5-2.8-1.81.81.5-1.11.7-1.90.11.7-0.7-1.60.01.71.4-1.5-0.30.6
Bone: final moment1.62.68.8-2.7-3.0-2.3-2.4-2.02.01.4-0.81.4-1.50.41.3-0.4-1.20.01.31.4-1.1-0.60.9
Food consumed during 24 hour testing period0.70.92.4-1.4-1.5-1.2-1.5-0.70.70.9-0.50.7-1.1-0.11.2-0.4-1.1-0.31.21.0-1.20.20.1
Glucose0.10.20.40.20.00.30.50.1-0.10.50.6-0.20.40.6-0.50.60.3-0.5-0.50.40.6-0.50.2
Heart weight0.00.10.3-0.1-0.4-0.2-0.3-0.30.30.50.2-0.2-0.30.20.10.2-0.1-0.20.10.5-0.1-0.20.3
Delay discount hyperbolic model param0.20.20.90.1-0.1-0.5-0.2-0.40.4-0.9-0.4-0.3-0.2-0.70.2-0.4-0.20.80.1-0.4-0.1-0.00.4
Intermittent access intake day 1-15 change0.40.82.50.60.81.30.61.5-1.51.00.6-0.5-0.40.00.50.20.1-1.60.50.6-0.71.3-1.4
Intermittent access intake escalation0.51.03.10.70.91.50.81.6-1.61.30.9-0.6-0.20.40.20.40.3-1.80.20.7-0.41.1-1.3
Intermittent access intake escalation 21.21.35.10.71.01.60.72.3-2.31.30.8-0.5-0.40.20.60.3-0.0-1.80.30.6-0.61.4-1.6
Intermitt. access day 1 inactive lever presses0.10.31.11.00.70.80.40.4-0.40.50.6-0.90.00.00.40.30.1-0.90.20.4-0.20.7-0.7
Intermitt. access day 15 inactive lever presses0.10.30.9-0.4-0.4-0.4-0.70.1-0.10.3-0.40.5-0.4-0.40.9-0.5-0.5-0.10.70.2-0.90.5-0.4
Intermitt. access escalation Index0.20.31.2-0.1-0.8-0.6-0.2-1.11.1-0.20.0-0.6-0.0-0.0-0.10.10.20.2-0.10.4-0.0-0.50.9
Intermittent access day 1 total infusions0.30.51.8-0.8-1.0-0.9-0.7-1.31.3-0.2-0.40.60.60.10.0-0.10.60.60.00.00.1-0.80.9
Intermittent access day 15 total infusions0.10.10.60.0-0.10.40.10.2-0.20.70.4-0.20.20.40.10.30.6-0.80.10.6-0.10.1-0.1
Intermittent access terminal intake (last 3 days)0.10.10.4-0.3-0.5-0.1-0.2-0.10.10.60.3-0.10.30.40.10.30.5-0.50.10.6-0.1-0.20.3
Intermittent access total infusions0.40.51.9-1.1-1.4-0.8-0.9-0.90.91.00.00.60.20.70.20.20.1-0.20.20.8-0.1-0.70.7
Intermittent access day 1 locomotion0.40.51.9-0.4-0.8-0.6-0.2-1.41.40.20.2-0.20.50.5-0.10.41.00.1-0.30.50.4-0.91.0
Intermittent access day 15 total locomotion0.61.12.50.8-0.30.50.8-0.60.60.71.3-1.31.61.1-0.91.41.5-0.9-0.91.11.0-1.21.1
Intermittent access total locomotion0.70.92.3-0.1-1.0-0.50.1-1.51.50.40.7-0.71.30.8-0.50.91.1-0.2-0.60.90.7-1.41.5
Intermittent access standard deviation0.71.43.8-1.2-1.1-0.6-1.50.7-0.71.9-0.20.9-1.70.11.8-0.4-0.3-1.31.71.3-1.71.0-0.8
Left kidney weight0.83.912.1-3.5-3.4-2.9-3.2-2.12.11.5-1.32.1-2.00.31.7-0.8-1.60.21.61.4-1.6-0.50.8
Right kidney weight0.94.215.6-3.5-3.9-3.2-3.2-2.42.41.7-1.11.8-1.60.71.3-0.4-1.40.31.21.7-1.2-1.21.6
Cocaine induced anxiety0.10.20.60.60.40.30.1-0.00.0-0.30.1-0.8-0.7-0.60.2-0.2-0.5-0.30.50.1-0.50.7-0.4
Post-drug Anxiety0.90.92.11.20.20.91.1-0.30.30.51.4-1.50.81.0-1.21.30.8-1.1-1.00.91.0-0.70.6
Baseline Anxiety1.01.23.9-0.3-0.70.30.6-0.40.41.71.20.01.32.0-1.01.50.9-1.0-1.21.21.2-1.51.0
Tail length0.31.23.3-1.8-1.8-0.9-0.6-1.51.51.70.21.10.11.6-0.20.60.2-0.5-0.31.20.3-1.20.9
Length with tail0.10.61.7-1.1-0.5-0.10.1-0.90.90.80.21.20.71.3-0.70.50.60.0-0.90.11.0-1.10.4
Length without tail0.20.61.80.51.31.40.91.1-1.1-0.10.50.20.50.6-0.90.50.5-0.2-1.1-0.71.0-0.1-0.6
Times rat made contact with spout2.02.35.2-1.6-0.8-1.0-2.00.5-0.50.8-1.21.5-2.2-1.12.3-1.4-2.0-0.32.30.3-2.31.7-1.4
Lifetime Intake0.60.72.5-1.5-1.6-1.1-1.2-1.01.01.0-0.20.90.20.70.40.1-0.2-0.10.30.8-0.2-0.80.8
Liver weight, left0.50.84.10.80.6-0.40.5-1.01.0-2.0-0.6-0.60.8-0.9-0.4-0.50.51.7-0.6-1.40.4-0.30.6
Liver weight, right0.50.94.00.10.8-0.6-0.00.1-0.1-2.0-1.30.5-0.0-1.40.2-1.2-0.22.00.1-1.9-0.20.4-0.2
Locomotor activity0.10.20.70.1-0.0-0.60.3-0.60.6-0.8-0.4-0.20.2-0.5-0.0-0.30.70.90.1-0.50.1-0.20.4
Locomotor testing distance0.10.20.6-0.1-0.5-0.80.0-0.70.7-0.3-0.2-0.20.1-0.20.0-0.10.60.50.10.00.1-0.40.6
Locomotor testing rearing0.20.41.20.40.2-0.40.4-0.90.9-1.1-0.3-0.40.4-0.3-0.5-0.10.61.1-0.5-0.80.6-0.60.7
Locomotion in novel chamber0.81.03.8-0.2-1.2-1.0-0.3-1.81.8-0.50.2-0.70.70.4-0.80.50.40.8-0.80.30.8-1.62.0
Locomotion in novel chamber post-restriction1.21.94.81.3-0.20.41.4-1.21.2-0.41.3-2.21.91.0-1.61.51.5-0.0-1.60.71.5-1.82.0
Fecal boli incidents, locomotor time 10.60.94.80.40.9-0.1-0.0-0.30.3-2.2-1.10.4-0.1-1.40.0-1.1-0.41.7-0.2-1.9-0.10.5-0.2
Change in fecal boli incidents, locomotor task2.12.16.3-0.6-1.40.30.6-0.80.82.11.6-0.71.52.5-1.61.91.5-1.1-1.11.81.0-2.11.7
Time >=10cm from walls, locomotor time 10.30.30.9-1.0-0.8-0.3-0.8-0.10.10.6-0.30.7-0.80.00.7-0.2-0.7-0.30.60.4-0.80.3-0.2
Bouts of movement, locomotor time 11.21.44.82.21.81.61.60.9-0.9-1.40.8-2.01.1-0.5-1.00.61.0-0.0-0.9-0.70.90.10.0
Total resting periods, locomotor time 11.41.54.72.22.11.71.71.2-1.2-1.60.6-1.71.1-0.6-1.10.31.00.2-1.0-1.10.80.3-0.2
Rest time, locomotor task time 10.70.92.80.11.71.30.61.7-1.7-0.6-0.40.7-0.0-0.6-0.0-0.6-0.10.10.2-1.3-0.61.3-1.6
Distance moved, locomotor task time 10.71.03.8-0.4-1.7-1.3-0.5-1.91.90.70.4-0.50.20.7-0.00.60.4-0.0-0.11.20.5-1.31.6
Vertical activity count, locomotor time 10.61.45.8-0.8-2.1-1.1-1.1-1.31.32.10.7-0.3-0.51.00.80.8-0.2-1.50.82.4-0.3-0.70.9
Time >=10cm from walls, locomotor time 20.81.23.2-1.8-1.3-1.2-1.70.1-0.11.0-0.81.7-1.5-0.01.3-0.7-1.5-0.21.20.4-1.40.5-0.5
Bouts of movement, locomotor time 21.62.57.2-0.50.2-1.6-1.2-1.11.1-2.7-2.30.9-0.7-2.61.4-2.2-1.12.61.1-2.1-0.71.1-0.4
Total resting periods, locomotor time 21.42.46.3-0.80.0-1.7-1.3-1.11.1-2.4-2.31.1-0.8-2.51.5-2.2-1.12.51.2-2.0-0.71.0-0.4
Rest time, locomotor task time 20.10.10.4-0.4-0.10.30.2-0.20.20.40.30.40.40.6-0.40.40.4-0.2-0.50.20.2-0.40.2
Distance moved, locomotor task time 20.60.71.8-0.5-0.4-0.4-1.00.7-0.71.20.10.3-1.1-0.11.3-0.2-1.0-1.11.31.0-0.70.9-0.8
Vertical activity count, locomotor time 20.70.94.6-0.1-0.70.1-0.30.3-0.32.11.1-0.3-0.21.00.70.9-0.1-2.10.62.0-0.20.1-0.2
Light reinforcement 10.30.81.90.80.2-0.00.9-1.01.0-0.90.3-0.61.30.2-1.00.51.40.8-1.1-0.41.1-1.11.1
Light reinforcement 20.40.61.40.5-0.2-0.20.5-1.11.1-0.60.3-0.80.90.3-0.90.50.90.6-0.8-0.10.9-1.11.2
Bone: marrow area1.22.65.9-2.1-1.5-2.4-2.0-1.71.7-0.6-2.11.7-1.6-1.41.8-1.8-1.41.51.9-0.6-1.80.6-0.1
Bone: maximum diameter1.12.15.3-2.3-2.1-2.2-2.2-1.81.80.3-1.41.3-1.5-0.51.5-1.1-1.20.81.50.4-1.40.00.4
Bone: maximum force1.62.88.4-2.9-2.8-2.3-2.6-1.61.61.6-1.01.7-1.90.21.6-0.7-1.4-0.11.71.4-1.6-0.10.4
Bone: maximum moment1.32.27.4-2.6-2.7-2.1-2.2-1.81.81.4-0.71.3-1.40.41.2-0.4-1.0-0.11.31.4-1.1-0.50.7
Mean time between licks in bursts0.10.31.00.50.6-0.00.00.2-0.2-1.0-0.3-0.9-0.3-1.00.3-0.5-0.40.50.3-0.6-0.30.6-0.2
Mean num. licks in bursts2.03.29.1-3.0-3.0-2.8-2.6-2.32.31.1-1.42.2-1.40.01.3-0.9-1.20.81.20.8-1.3-0.71.0
Cd content in liver3.84.39.21.70.00.72.2-2.02.0-0.61.6-2.22.91.5-2.72.03.00.5-2.70.22.7-2.82.6
Co content in liver1.82.15.90.5-0.51.20.90.4-0.42.42.1-1.20.72.3-1.12.01.1-2.3-1.02.21.1-1.10.6
Cu content in liver0.60.72.0-0.6-1.4-0.5-0.3-0.90.91.10.6-0.40.11.2-0.50.80.3-0.5-0.31.30.5-1.31.3
Fe content in liver1.01.22.90.7-0.11.10.80.6-0.61.21.7-1.40.71.5-1.11.60.8-1.6-1.01.41.1-0.90.7
K content in liver0.10.10.5-0.0-0.7-0.5-0.4-0.60.6-0.00.0-0.4-0.10.1-0.00.1-0.10.10.10.40.0-0.40.7
Mg content in liver0.40.41.4-0.3-0.1-0.8-0.6-0.80.8-1.0-0.90.3-0.5-0.90.3-0.8-0.61.20.4-0.8-0.30.10.2
Mn content in liver0.40.51.0-0.7-0.5-0.9-1.0-0.20.2-0.2-0.80.6-0.9-0.70.8-0.8-0.90.50.9-0.2-0.80.5-0.2
Na content in liver4.34.610.0-2.5-1.5-2.7-3.2-0.70.7-0.6-2.62.1-2.8-2.12.7-2.5-3.01.42.8-0.6-2.71.6-0.8
Rb content in liver6.07.012.92.10.02.02.7-1.01.01.13.2-3.32.93.1-3.63.52.9-1.3-3.51.73.6-3.42.9
Se content in liver0.30.31.2-0.4-0.3-0.3-0.80.3-0.30.2-0.30.2-1.1-0.40.8-0.4-1.1-0.30.90.3-0.80.6-0.5
Sr content in liver0.50.51.1-0.7-0.7-1.1-0.9-0.50.5-0.4-0.90.7-0.6-0.70.8-0.8-0.40.70.8-0.2-0.80.4-0.0
Zn content in liver1.51.75.2-1.3-1.3-2.1-1.3-2.32.3-0.9-1.50.7-0.8-1.00.8-1.2-0.51.80.9-0.6-0.8-0.20.8
Bone: minimum diameter1.42.56.0-2.4-1.7-2.2-2.2-1.21.2-0.1-1.92.0-2.0-1.11.8-1.7-1.51.21.9-0.3-1.80.6-0.2
Time in familiar zone, hab. session 11.71.73.51.20.11.31.30.3-0.31.21.9-1.71.41.6-1.31.71.3-1.7-1.21.51.2-0.90.6
Time in novel zone, hab. session 12.02.06.3-1.8-0.1-1.3-1.2-0.10.1-1.2-2.22.5-1.4-1.51.1-1.9-1.02.11.1-2.0-1.10.8-0.8
Total zone transitions, hab. session 10.91.35.6-1.8-2.4-1.4-1.2-1.11.11.70.20.9-0.01.30.30.50.0-0.70.31.7-0.3-1.11.1
Total locomotion distance, hab. session 12.02.811.5-2.5-3.4-2.4-1.6-2.32.32.0-0.21.30.11.50.20.40.3-0.20.32.0-0.3-1.81.9
Locomotion velocity, hab. session 11.82.59.8-2.0-3.1-2.3-1.3-2.62.61.5-0.10.70.31.30.00.50.40.10.11.8-0.1-1.92.2
Time in familiar zone, hab. session 20.20.20.7-0.4-0.8-0.3-0.3-0.80.80.70.2-0.1-0.00.40.10.2-0.0-0.40.30.7-0.3-0.20.3
Time in novel zone, hab. session 20.10.10.30.20.2-0.10.20.0-0.0-0.5-0.1-0.10.1-0.1-0.30.00.30.4-0.4-0.40.4-0.30.3
Total zone transitions, hab. session 20.81.14.5-1.6-2.1-1.4-0.9-1.21.21.1-0.01.00.31.00.10.40.4-0.20.01.2-0.0-1.31.3
Total locomotion distance, hab. session 21.21.56.1-1.8-2.5-1.5-1.2-1.41.41.80.11.20.21.30.20.50.2-0.60.21.7-0.2-1.31.2
Locomotion velocity, hab. session 21.21.77.0-2.1-2.6-1.9-1.4-1.51.51.7-0.21.3-0.01.00.50.20.0-0.30.51.6-0.5-1.11.2
Novel to familiar place preference ratio0.80.82.31.30.81.11.11.5-1.50.41.1-1.30.50.4-0.50.80.6-1.1-0.50.70.50.1-0.2
Novelty place preference0.91.03.11.30.81.31.01.8-1.80.71.2-1.20.50.5-0.40.90.5-1.4-0.40.80.40.3-0.4
Time in novel zone, NPP test0.80.91.91.30.71.21.21.4-1.40.61.3-1.30.70.6-0.61.00.9-1.2-0.60.80.6-0.1-0.0
Total zone transitions, NPP test0.50.73.2-1.5-1.8-1.2-1.1-0.90.91.0-0.21.0-0.10.60.40.1-0.1-0.20.41.0-0.4-0.70.8
Total locomotion distance, NPP test0.60.93.5-1.3-1.9-1.0-0.9-0.70.71.70.20.5-0.20.90.40.40.0-0.80.41.6-0.4-0.70.7
Locomotion velocity, NPP test0.50.72.8-1.3-1.7-0.8-1.1-0.50.51.70.20.6-0.20.90.40.4-0.3-0.80.41.5-0.4-0.60.6
Intraocular pressure0.30.41.0-0.7-0.2-0.7-0.60.0-0.0-0.4-1.01.0-0.5-0.60.3-0.8-0.71.00.4-0.7-0.50.3-0.2
Delta distance traveled before/after self-admin0.60.72.0-1.2-0.5-1.0-0.9-0.50.5-0.2-1.21.4-0.8-0.60.8-1.1-0.80.80.6-0.6-0.80.5-0.4
Delta ambulatory time before/after self-admin0.81.02.8-1.4-0.7-1.1-1.20.0-0.00.2-1.31.7-1.1-0.61.2-1.2-1.20.61.0-0.4-1.20.7-0.7
Parametrial fat weight1.94.413.1-1.6-3.5-2.1-1.3-3.63.61.00.60.00.82.0-1.21.50.40.2-1.32.01.3-3.43.6
Pavlov. Cond. lever latency3.44.310.10.9-0.31.91.80.8-0.82.92.9-1.52.03.2-2.02.92.1-3.0-1.92.61.9-1.70.8
Pavlov. Cond. magazine entry latency5.06.512.7-2.1-1.1-3.4-3.1-1.81.8-2.6-3.52.1-2.7-3.12.4-3.2-2.93.62.3-2.3-2.31.2-0.1
Pavlov. Cond. change in total contacts5.96.212.1-1.60.4-2.0-2.5-0.00.0-2.4-3.32.3-3.2-3.52.8-3.4-3.12.72.6-2.6-2.62.6-1.8
Pavlov. Cond. index score4.65.812.4-1.4-0.1-2.6-2.4-1.21.2-3.1-3.41.9-2.5-3.42.2-3.3-2.63.52.2-2.8-2.21.6-0.7
Pavlov. Cond. latency score3.84.810.4-1.3-0.3-2.4-2.3-1.21.2-2.8-3.11.7-2.2-3.12.0-2.9-2.43.21.9-2.5-2.01.4-0.5
Pavlov. Cond. lever contacts4.75.611.3-1.6-0.3-2.6-2.5-1.21.2-2.8-3.42.1-2.4-3.22.3-3.2-2.53.32.2-2.6-2.31.6-0.7
Pavlov. Cond. magazine entry number4.45.611.11.60.22.52.60.8-0.82.53.3-2.12.73.2-2.43.22.9-3.1-2.22.52.3-1.80.9
Pavlov. Cond. intertrial magazine entries2.83.36.01.70.31.72.10.4-0.41.12.4-2.22.12.2-2.22.42.3-1.7-2.11.52.1-1.71.3
Pavlov. Cond. lever-magazine prob. diff.5.16.313.2-1.6-0.3-2.9-2.6-1.41.4-3.1-3.62.0-2.6-3.52.4-3.4-2.73.62.3-2.8-2.41.6-0.6
Pavlov. Cond. response bias5.97.314.4-1.8-0.1-2.7-2.8-0.70.7-2.9-3.82.5-3.0-3.72.8-3.7-3.13.52.7-3.0-2.72.2-1.3
Pavlov. Cond. lever latency0.60.83.31.01.41.50.91.8-1.80.10.6-0.20.2-0.0-0.10.30.1-0.9-0.1-0.10.30.8-1.1
Pavlov. Cond. magazine entry latency0.60.72.10.61.40.50.20.9-0.9-1.3-0.7-0.1-0.3-1.20.3-0.9-0.40.80.3-1.5-0.51.2-1.1
Pavlov. Cond. change in total contacts1.11.83.90.7-0.7-0.10.9-1.61.60.11.0-1.61.61.3-1.71.31.70.1-1.70.61.5-2.02.0
Pavlov. Cond. index score0.10.20.60.1-0.1-0.5-0.0-0.80.8-0.7-0.3-0.50.2-0.3-0.2-0.20.20.8-0.2-0.5-0.0-0.30.5
Pavlov. Cond. latency score0.10.20.6-0.0-0.1-0.5-0.2-0.60.6-0.7-0.5-0.3-0.1-0.40.0-0.4-0.00.70.1-0.5-0.3-0.00.2
Pavlov. Cond. lever contacts0.60.83.5-1.0-1.3-1.6-0.9-1.91.9-0.4-0.80.2-0.3-0.20.1-0.4-0.21.10.1-0.1-0.4-0.71.1
Pavlov. Cond. magazine entry number0.60.82.6-1.6-1.6-1.2-1.2-0.90.91.1-0.31.2-0.70.40.8-0.2-0.6-0.30.80.9-0.6-0.30.4
Pavlov. Cond. intertrial magazine entries1.11.75.2-1.9-2.0-2.3-1.8-1.91.90.0-1.31.2-1.2-0.51.0-0.9-0.91.11.00.2-0.9-0.50.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.80.20.2-0.40.0-0.50.5-0.9-0.4-0.50.1-0.5-0.2-0.40.10.9-0.1-0.7-0.1-0.10.3
Pavlov. Cond. response bias0.30.31.5-0.0-0.4-0.8-0.2-1.21.2-0.7-0.4-0.40.1-0.2-0.3-0.20.11.0-0.3-0.40.0-0.50.8
Time in closed arm before self-admin0.00.10.2-0.2-0.5-0.1-0.1-0.30.30.30.2-0.20.00.20.00.20.2-0.3-0.00.5-0.1-0.20.3
Time in closed arm after self-admin0.30.40.60.40.30.80.60.7-0.70.60.7-0.40.70.8-0.60.70.7-0.7-0.50.40.6-0.3-0.0
Time in open arm before self-admin0.30.41.71.21.30.90.80.4-0.4-0.80.2-0.50.2-0.4-0.30.00.00.1-0.2-0.70.40.4-0.5
Time in open arm after self-admin1.41.53.4-1.3-1.1-1.6-1.6-0.60.60.3-1.21.0-1.9-1.01.8-1.3-1.40.31.80.2-1.91.0-0.5
Bone: periosteal estimation1.83.910.2-3.2-2.6-2.9-2.9-1.81.80.5-2.02.3-2.2-0.92.2-1.7-1.81.02.30.3-2.10.40.1
Bone: periosteal perimeter1.22.14.8-2.1-1.7-2.2-2.0-1.51.5-0.4-1.71.5-1.5-1.01.4-1.4-1.11.41.5-0.3-1.40.20.3
Bone: post-yield work1.42.17.8-1.7-2.2-2.6-1.3-2.82.8-0.4-1.10.7-0.2-0.10.3-0.60.01.70.20.0-0.3-1.31.8
Progressive ratio test 1 active lever presses0.40.51.7-0.9-0.6-0.8-0.7-1.31.3-0.8-0.70.40.0-0.60.6-0.50.00.80.5-0.3-0.3-0.10.4
Progressive ratio test 1 breakpoint0.40.51.6-0.8-0.5-0.7-0.6-1.31.3-0.9-0.70.40.0-0.70.6-0.60.00.90.5-0.4-0.3-0.10.3
Progressive ratio test 1 inactive lever presses0.20.31.1-0.00.0-0.3-0.2-0.90.9-1.1-0.5-0.20.3-0.90.5-0.60.30.60.4-0.4-0.40.40.0
Progressive ratio test 2 active lever presses0.20.30.9-0.50.1-0.2-0.1-0.80.8-0.9-0.50.40.6-0.4-0.1-0.4-0.30.9-0.1-0.80.2-0.10.1
Progressive ratio test 2 breakpoint0.20.30.9-0.40.1-0.1-0.0-0.80.8-1.0-0.50.40.7-0.4-0.2-0.3-0.20.9-0.2-0.80.3-0.20.2
Progressive ratio test 2 inactive lever presses0.20.31.3-0.5-0.5-0.6-0.5-1.11.1-0.3-0.40.30.4-0.20.4-0.3-0.40.50.1-0.1-0.2-0.10.3
Incentive Sensitization - Responses0.20.31.2-0.40.50.0-0.10.1-0.1-1.0-0.70.70.2-0.60.1-0.7-1.00.90.0-1.10.00.3-0.4
Incentive Sensitization - Breakpoint0.20.31.0-0.40.3-0.1-0.10.0-0.0-0.9-0.70.70.4-0.5-0.0-0.5-0.90.9-0.0-1.00.10.1-0.2
Sum of active levers in priming session hrs 5-61.31.27.21.21.0-0.10.7-0.80.8-2.7-0.6-0.80.9-1.3-0.7-0.50.41.9-0.8-1.70.8-0.40.7
Progressive ratio0.60.92.00.3-0.50.10.6-1.31.30.40.8-0.71.21.2-1.21.00.8-0.2-1.20.71.1-1.41.3
Food seeking constrained by brief footshock0.60.71.61.20.91.31.00.9-0.90.21.0-1.20.40.6-0.90.91.1-0.8-0.90.20.9-0.2-0.1
Seeking ratio, punishment vs. effort0.81.12.7-0.70.4-0.4-1.11.1-1.1-0.6-1.10.9-1.6-1.31.3-1.2-1.00.51.2-0.9-1.11.4-1.2
Retroperitoneal fat weight1.56.321.4-1.2-3.3-2.4-0.7-4.44.4-0.20.4-0.61.52.0-2.21.51.11.7-2.21.02.1-4.44.6
Reaction time number correct0.30.51.60.81.00.51.10.5-0.5-1.3-0.1-0.41.0-0.4-0.7-0.01.00.8-0.7-1.10.6-0.10.0
Reaction time mean minus median0.10.20.70.1-0.6-0.1-0.1-0.40.40.60.4-0.60.10.40.10.30.3-0.50.10.8-0.2-0.20.4
Reaction time mean minus median AUC0.30.82.00.9-0.30.40.9-0.60.60.20.9-1.41.10.8-1.01.01.4-0.4-1.00.70.9-1.11.2
Reaction time num false alarms0.50.82.51.01.11.20.71.6-1.60.60.7-0.7-0.10.00.30.20.0-1.30.40.4-0.31.2-1.3
Reaction time num false alarms AUC0.30.41.30.71.00.70.51.2-1.20.00.1-0.3-0.3-0.40.4-0.3-0.2-0.50.5-0.2-0.31.1-1.1
Reaction time trials correct on left0.30.51.60.81.00.51.10.5-0.5-1.3-0.1-0.41.0-0.4-0.7-0.01.00.8-0.7-1.10.6-0.10.0
Reaction time trials on left0.30.51.80.81.00.51.10.5-0.5-1.3-0.1-0.40.9-0.4-0.7-0.01.00.8-0.8-1.10.6-0.20.1
Reaction time mean0.20.31.5-0.1-0.7-0.4-0.3-1.21.20.30.0-0.40.00.3-0.10.2-0.10.1-0.10.40.0-0.50.7
Reaction time mean AUC0.10.10.9-0.0-0.3-0.3-0.2-1.01.0-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.20.4-0.1-0.10.0-0.30.5
Median of all reaction times0.20.32.0-0.3-0.6-0.6-0.5-1.41.4-0.1-0.2-0.1-0.10.0-0.1-0.1-0.30.50.00.0-0.0-0.40.6
Reaction time omissions0.30.52.80.30.4-0.40.1-0.50.5-1.7-0.8-0.0-0.1-0.9-0.2-0.70.01.5-0.1-1.40.1-0.00.3
Reaction time false alarm rate0.40.61.80.20.50.5-0.21.1-1.10.80.10.1-0.9-0.30.9-0.3-0.8-1.01.00.4-0.81.3-1.3
Reaction time premature initiation rate1.11.53.4-1.8-0.9-1.1-1.70.5-0.50.9-1.21.9-1.4-0.51.6-1.2-1.50.11.60.0-1.71.1-1.0
Reaction time premature initiations0.61.02.7-1.3-0.1-0.7-1.00.9-0.90.0-1.31.6-0.9-0.81.1-1.3-0.90.61.1-0.7-1.31.1-1.1
Std. dev. reaction times0.20.30.9-0.0-0.8-0.3-0.0-0.90.90.50.4-0.50.30.6-0.40.50.4-0.2-0.30.70.2-0.70.9
Reaction time trials completed0.30.51.80.81.00.51.10.5-0.5-1.3-0.1-0.40.9-0.4-0.7-0.01.00.8-0.8-1.10.6-0.20.1
Reaction time trials AUC0.20.41.30.60.80.30.90.4-0.4-1.1-0.1-0.30.9-0.3-0.7-0.00.90.8-0.7-1.00.6-0.20.1
Run reversals in cocaine runway, females2.82.86.8-2.5-1.9-1.7-2.60.1-0.12.0-1.22.1-2.2-0.12.2-1.1-1.8-0.62.21.0-2.11.0-0.9
Run reversals in cocaine runway, males0.40.41.10.70.91.00.80.9-0.90.20.5-0.40.50.2-0.20.30.9-0.7-0.20.00.20.4-0.6
Latency to leave start box in cocaine runway1.21.43.10.3-0.40.41.1-0.80.80.41.2-0.91.71.3-1.61.41.8-0.4-1.50.71.5-1.71.5
Latency to leave start box in cocaine runway, F0.20.30.80.10.20.00.6-0.10.1-0.9-0.0-0.20.6-0.1-0.70.10.90.7-0.7-0.60.7-0.50.5
Latency to leave start box in cocaine runway, M2.32.14.00.4-0.80.61.2-1.01.01.21.7-1.11.92.0-1.61.91.5-1.2-1.61.61.6-1.91.6
Std. dev. time between licks in bursts0.40.61.70.2-0.3-1.1-0.6-0.80.8-1.3-0.9-0.5-0.6-1.30.7-0.8-0.51.20.7-0.6-0.70.20.5
Total sessions with >9 infusions2.42.99.4-3.1-2.7-2.7-2.4-2.52.50.7-1.32.1-0.40.21.2-0.7-1.01.10.80.4-0.8-1.01.2
Short access day 1 total inactive lever presses0.30.31.0-1.0-0.6-0.7-0.7-1.01.00.3-0.61.00.1-0.10.6-0.4-0.20.20.6-0.0-0.40.1-0.1
Short access day 10 total inactive lever presses0.30.72.91.21.71.61.01.1-1.1-0.30.2-0.40.3-0.4-0.0-0.10.0-0.50.0-0.6-0.11.2-1.4
Short access day 1 total infusions0.70.94.0-2.0-1.2-1.2-1.1-1.21.20.9-0.81.8-0.30.40.7-0.5-0.80.40.40.0-0.6-0.2-0.0
Short access day 10 total infusions1.21.54.6-2.1-1.7-1.8-1.7-1.91.90.1-1.31.8-0.4-0.31.1-0.8-0.50.90.8-0.0-0.8-0.40.5
Short access total infusions1.31.76.2-2.5-2.3-2.0-1.9-1.71.70.9-0.91.8-0.30.50.8-0.4-0.60.60.70.6-0.6-0.90.9
Short access day 1 locomotion0.30.42.1-1.2-0.7-0.4-0.7-0.50.51.40.10.9-0.30.70.80.1-0.5-0.60.30.7-0.3-0.1-0.2
Short access day 10 total locomotion1.22.26.2-2.0-2.0-2.5-2.1-1.91.9-0.2-1.41.0-1.2-1.02.1-1.2-0.60.91.90.3-1.40.20.5
Short access total locomotion1.72.16.7-2.0-2.6-2.2-1.5-2.62.61.2-0.20.70.20.90.70.30.30.20.31.3-0.0-1.61.8
One hour access (0.3 mA shock)0.30.41.00.2-0.4-0.20.1-1.01.0-0.9-0.0-0.61.0-0.2-0.60.10.60.6-0.5-0.10.4-0.71.0
Compulsive drug intake0.40.42.10.40.2-0.60.3-0.70.7-1.5-0.4-0.40.6-0.4-0.7-0.2-0.11.3-0.4-0.80.6-0.50.7
One hour access (shock baseline)0.20.31.20.5-0.20.50.40.0-0.00.50.8-0.80.60.5-0.20.71.1-0.8-0.50.80.3-0.40.4
Social response proportion0.70.82.70.7-0.1-0.10.8-0.70.7-0.80.4-0.91.30.3-1.10.61.60.6-1.0-0.11.1-1.31.4
Social responses0.60.72.41.20.70.21.0-0.70.7-1.60.1-1.10.9-0.5-0.80.11.50.9-0.7-0.80.8-0.40.7
Social time0.70.93.31.20.91.01.40.1-0.1-0.40.8-0.91.20.5-1.30.81.8-0.0-1.1-0.31.3-0.70.4
Soleus weight0.82.410.3-2.7-3.2-1.9-2.0-1.01.02.6-0.01.1-0.71.40.80.3-0.6-0.90.92.3-0.9-1.11.1
Bone: stiffness1.22.05.7-2.4-2.2-1.5-2.2-0.60.61.9-0.51.4-1.60.51.6-0.4-1.4-0.91.61.6-1.40.2-0.1
Tibialis anterior weight2.68.729.3-5.4-5.0-4.3-4.6-2.52.52.8-1.93.5-2.60.42.8-1.3-2.6-0.02.92.2-2.7-0.40.8
Time to tail flick, vehicle, before self-admin0.10.10.4-0.1-0.4-0.3-0.20.6-0.60.50.1-0.20.10.10.30.10.1-0.30.30.6-0.2-0.00.2
Time to tail flick, vehicle, after self-admin1.01.34.01.62.01.41.60.8-0.8-1.90.1-0.70.9-0.7-1.1-0.01.20.8-1.1-1.71.00.2-0.4
Time to tail flick, test, before self-admin0.30.41.20.10.2-0.1-0.20.5-0.50.1-0.40.0-0.7-0.71.0-0.7-0.3-0.10.9-0.1-1.11.1-0.9
Time to tail flick, test, after self-admin2.32.45.30.11.00.0-0.91.8-1.8-1.2-1.40.6-2.0-2.31.9-1.8-1.50.51.9-1.2-1.82.3-1.8
Delta time to tail flick, vehicle, before/after SA0.30.31.20.50.50.30.5-0.20.2-1.1-0.1-0.10.5-0.1-0.80.10.60.8-0.8-0.80.7-0.40.4
Delta time to tail flick, test, before/after SA0.40.40.9-0.5-0.2-0.4-0.80.2-0.2-0.6-0.70.6-0.9-0.80.7-0.7-1.00.40.8-0.3-0.60.5-0.2
Tibia length0.30.81.90.4-0.50.30.6-0.50.51.11.1-0.90.81.2-0.61.11.4-1.0-0.71.20.8-0.90.8
Ambulatory time before self-admin0.60.83.8-0.2-0.40.90.00.0-0.01.91.4-0.50.11.4-0.31.2-0.2-1.9-0.11.60.2-0.3-0.0
Ambulatory time after self-admin1.41.74.3-2.0-1.3-0.7-1.70.1-0.12.1-0.41.6-1.60.51.5-0.4-2.0-1.11.41.2-1.50.8-0.9
Bone: tissue strength0.20.20.6-0.5-0.10.0-0.40.0-0.00.5-0.10.4-0.8-0.00.5-0.2-0.5-0.40.50.2-0.60.5-0.5
Total heroin consumption0.70.83.30.60.60.10.9-0.90.9-1.8-0.2-0.51.1-0.5-0.90.00.81.4-1.0-1.21.1-0.80.8
Bone: trabecular number0.30.51.7-1.1-1.3-0.8-0.9-0.60.61.0-0.10.7-0.50.60.40.1-0.3-0.40.50.9-0.5-0.30.4
Bone: trabecular spacing0.71.05.11.01.30.10.30.2-0.2-2.3-0.9-0.4-0.1-1.70.1-1.0-0.31.60.1-1.9-0.00.7-0.4
Bone: trabecular thickness2.73.47.5-0.9-2.6-0.7-0.1-2.02.02.41.6-0.61.42.7-1.32.11.4-1.3-1.32.61.3-2.72.5
Bone: trabecular tissue density0.10.20.80.2-0.20.40.30.3-0.30.70.6-0.50.10.5-0.10.60.3-0.9-0.20.80.2-0.10.1
Water consumed over 24 hours1.92.67.3-0.21.30.8-0.52.6-2.60.2-0.81.1-1.7-1.41.8-1.4-1.6-0.61.8-0.7-1.82.6-2.7
Number of responses in last shaping day0.30.41.3-0.90.0-0.3-0.3-0.70.70.0-0.81.2-0.3-0.30.6-0.8-0.40.50.5-0.6-0.60.6-0.7