Iqck

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Iqck 0.33 0.1 0.0e+00 0.2 0.24 0.25 0.25 5.4e-22 3.2e-26 8.1e-28 1.8e-27
2 NAcc intron excision ratio chr1_173199530_173217081 0.03 0.02 2.5e-03 0.01 0.01 0.01 0.01 3.6e-02 1.4e-02 5.9e-02 3.6e-02
3 Adipose isoform ratio NM_001401714.1 0.19 0.1 5.6e-17 0.12 0.11 0.11 0.12 9.8e-13 4.8e-12 1.4e-12 4.6e-13
4 Adipose alternative polyA XM_039101166.1 0.34 0.1 0.0e+00 0.22 0.22 0.25 0.22 2.0e-23 5.3e-24 2.1e-27 1.6e-24
5 Brain mRNA stability Iqck 0.05 0.04 1.6e-03 0.04 0.03 0.02 0.03 3.2e-04 1.4e-03 1.0e-02 1.4e-03
6 Adipose isoform ratio XM_039101166.1 0.32 0.09 0.0e+00 0.21 0.22 0.27 0.23 2.8e-23 2.1e-24 2.0e-29 2.1e-25
7 IL gene expression Iqck 0.28 0.14 3.7e-03 0.02 0 -0.01 -0 1.3e-01 3.1e-01 7.0e-01 3.5e-01
8 OFC gene expression Iqck 0.36 0.16 1.0e-03 0.06 0.12 0.13 0.12 1.6e-02 8.3e-04 4.8e-04 7.8e-04
9 BLA gene expression Iqck 0.17 0.08 7.1e-06 0.06 0.1 0.06 0.1 3.8e-04 3.1e-06 2.8e-04 3.0e-06
10 PL intron excision ratio chr1_173199530_173217081 0.02 0.02 8.6e-03 0.02 0.01 0.01 0.01 4.8e-03 2.2e-02 4.9e-02 1.2e-02
11 LHb gene expression Iqck 0.4 0.16 3.5e-04 0 0.1 0.06 0.05 3.0e-01 1.9e-03 1.6e-02 2.3e-02
12 Adipose alternative TSS XM_039101167.1 0.04 0.02 2.7e-03 0.01 0.01 0.03 0.03 6.9e-03 1.4e-02 2.4e-04 2.9e-04
13 Adipose alternative TSS XM_006230149.4 0.04 0.02 2.9e-03 0.01 0.01 0.03 0.03 8.1e-03 1.6e-02 2.2e-04 3.6e-04
14 PL gene expression Iqck 0.11 0.06 4.7e-06 0.02 0.06 0.05 0.06 1.3e-03 3.7e-07 3.4e-06 8.9e-07
15 Adipose alternative polyA NM_001401714.1 0.31 0.11 0.0e+00 0.19 0.18 0.22 0.19 3.5e-20 4.2e-20 3.8e-24 1.3e-20
16 Brain gene expression Iqck 0.18 0.08 2.2e-10 0.09 0.12 0.11 0.12 2.3e-08 6.1e-11 2.0e-10 2.0e-11
17 NAcc gene expression Iqck 0.13 0.07 1.0e-06 0.06 0.07 0.07 0.08 3.4e-07 4.5e-08 8.3e-09 2.5e-09
18 PL intron excision ratio chr1_173217154_173220756 0.07 0.04 1.4e-04 0.03 0.03 0.03 0.03 2.9e-04 1.6e-04 3.9e-04 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.50.82.01.2-1.1-1.3-1.11.4-1.1-0.80.10.80.3-0.21.1-1.10.60.7-0.30.4-0.5
Area under the delay curve0.30.31.6-0.20.60.30.2-0.2-0.00.3-0.90.9-0.50.7-0.40.40.80.30.61.3-0.0
BMI with tail1.44.410.42.7-3.2-2.8-2.82.3-2.3-1.82.4-0.61.8-2.22.3-2.4-0.91.6-1.6-1.10.0
BMI without tail4.08.219.03.9-4.4-4.0-3.83.3-3.3-2.63.0-0.51.9-2.93.2-3.3-0.82.6-2.1-1.0-0.4
Body weight1.24.910.93.2-3.3-3.3-3.12.8-2.8-1.92.10.71.7-1.82.2-2.20.12.2-1.4-0.2-0.3
Weight adjusted by age0.91.15.30.2-0.80.1-0.30.10.1-0.61.6-2.30.3-1.40.7-0.8-1.60.1-0.7-1.90.1
Bone surface0.71.23.61.9-1.6-1.5-1.50.9-1.5-0.31.00.41.3-1.00.3-0.4-0.21.6-1.1-0.50.5
Bone volume0.91.63.92.0-1.8-1.9-1.81.5-1.8-1.00.60.81.1-0.70.8-0.80.31.5-1.0-0.30.1
Breakpoint value in progressive ratio session1.51.74.6-1.71.71.81.5-0.21.70.2-0.4-0.7-2.11.00.6-0.60.5-1.61.90.3-1.5
Number of licking bursts3.03.58.5-2.22.32.42.2-2.91.82.3-1.5-0.2-0.51.1-2.92.9-0.5-1.20.10.61.6
Context. condit. distance diff. score0.30.41.1-1.00.60.91.0-0.31.10.10.2-0.7-0.60.00.2-0.2-0.3-1.00.20.2-0.3
Locomotion velocity, session 10.10.10.70.1-0.1-0.2-0.20.1-0.3-0.1-0.60.8-0.00.4-0.40.40.50.4-0.1-0.00.2
Locomotion distance, session 10.50.61.80.9-0.9-0.9-0.91.2-0.7-0.70.50.1-0.1-0.41.3-1.30.30.4-0.1-0.1-0.8
Locomotion velocity, session 20.20.20.70.10.30.1-0.1-0.1-0.20.4-0.80.9-0.20.7-0.60.70.70.40.50.50.1
Locomotion distance, session 20.91.23.21.7-1.6-1.8-1.61.4-1.6-0.60.30.90.8-0.60.8-0.80.41.4-0.7-0.5-0.1
Locomotion velocity, session 30.20.20.50.6-0.7-0.6-0.60.7-0.5-0.10.30.20.4-0.40.4-0.40.20.60.00.2-0.2
Locomotion distance, session 31.01.02.60.8-1.1-0.6-0.4-0.5-0.60.91.0-0.21.6-1.2-1.00.9-1.01.2-1.6-1.21.4
Stereotopy head waving bouts, day 30.50.61.3-1.01.00.90.9-0.20.90.0-0.5-0.2-1.10.70.3-0.30.4-1.11.01.2-0.9
Stereotopy head waving duration, day 30.50.61.6-0.80.90.80.60.20.7-0.1-0.4-0.2-1.30.70.7-0.60.6-1.01.11.2-1.1
Locomotion velocity, session 72.02.24.81.8-2.0-1.2-1.70.1-1.50.11.5-0.42.1-2.0-0.40.4-1.12.2-1.9-1.81.4
Locomotion distance, session 71.01.33.10.7-0.7-0.2-0.6-0.9-0.70.60.6-0.31.8-1.1-1.31.2-1.11.4-1.7-1.71.7
Stereotopy head waving bouts, day 70.30.40.90.5-0.3-0.4-0.40.9-0.3-0.7-0.20.4-0.70.10.9-0.90.60.20.50.9-0.8
Stereotopy head waving duration, day 70.81.02.11.4-1.4-1.3-1.31.4-1.0-1.00.8-0.00.1-0.81.3-1.40.10.8-0.20.2-0.6
Locomotion velocity, session 80.10.10.20.1-0.1-0.20.10.30.0-0.2-0.30.5-0.50.20.2-0.20.50.00.10.3-0.2
Locomotion distance, session 80.10.10.40.2-0.6-0.4-0.30.4-0.2-0.20.3-0.10.2-0.40.5-0.5-0.10.2-0.5-0.3-0.1
Degree of sensitization distance0.90.91.8-0.71.00.40.20.60.3-1.1-1.20.6-1.11.30.9-0.81.2-0.91.40.9-1.2
Degree of sensitization stereotypy0.70.71.91.4-1.4-1.3-1.11.2-1.1-0.80.50.50.3-0.60.8-0.80.21.0-0.30.1-0.2
Conditioned locomotion1.01.22.30.1-0.10.70.1-1.50.11.51.1-1.31.2-1.1-1.31.3-1.50.9-0.7-1.31.4
Cocaine response after cond. corrected0.20.20.4-0.50.50.60.4-0.50.40.3-0.6-0.0-0.00.4-0.60.7-0.0-0.40.30.30.2
Cocaine response after cond. not corrected0.10.10.20.3-0.4-0.2-0.2-0.1-0.20.1-0.0-0.00.5-0.3-0.30.3-0.20.1-0.40.40.3
Cocaine response before conditioning1.41.74.32.0-2.1-1.9-1.60.9-1.7-0.41.30.41.4-1.50.3-0.3-0.41.5-1.70.20.7
Saline control response0.20.20.6-0.60.60.40.40.20.5-0.5-0.2-0.3-0.70.40.5-0.50.2-0.70.70.0-0.7
Bone: connectivity density0.30.41.11.0-1.0-0.8-0.80.7-0.7-0.10.7-0.20.5-0.80.7-0.7-0.30.7-0.5-0.10.1
Bone: cortical apparent density0.40.61.2-1.01.00.81.1-0.80.90.8-0.70.3-0.50.8-0.91.00.2-0.80.4-0.30.2
Bone: cortical area1.92.87.02.5-2.3-2.6-2.51.9-2.5-1.60.71.31.5-0.81.0-1.00.51.9-1.20.20.1
Bone: cortical porosity0.60.61.50.8-1.0-0.7-1.00.9-0.6-0.40.9-0.60.4-1.01.2-1.2-0.30.7-0.4-0.6-0.5
Bone: cortical porosity0.40.41.40.3-0.6-0.1-0.40.6-0.1-0.20.9-1.0-0.0-0.91.1-1.2-0.40.3-0.1-0.7-0.6
Bone: cortical thickness1.11.84.31.6-1.2-2.0-1.81.7-2.0-1.5-0.72.10.70.40.7-0.61.41.2-0.31.3-0.3
Bone: cortical thickness1.21.46.40.20.2-0.9-0.61.2-0.9-1.0-1.92.5-0.21.60.1-0.02.10.30.71.8-0.6
Bone: cortical tissue density0.40.61.2-1.01.10.81.1-0.80.90.8-0.70.3-0.50.8-0.90.90.2-0.80.5-0.40.2
Condit. Reinf. active minus inactive responses0.20.30.6-0.80.40.70.6-0.00.70.20.0-0.7-0.50.00.6-0.6-0.1-0.60.6-0.5-0.5
Condit. Reinf. active-inactive response ratio0.30.41.5-0.4-0.10.50.4-0.10.60.40.8-1.2-0.2-0.60.5-0.6-0.7-0.40.2-1.1-0.3
Condit. Reinf. active responses0.20.20.7-0.80.50.50.40.10.6-0.0-0.4-0.3-0.30.40.5-0.50.2-0.70.6-0.3-0.5
Condit. Reinf. inactive responses0.10.10.6-0.40.4-0.1-0.00.40.0-0.5-0.80.5-0.00.60.2-0.20.5-0.50.20.3-0.3
Incentive salience index mean0.30.31.20.0-0.40.1-0.1-0.30.00.60.8-1.00.7-0.8-0.10.0-0.90.2-0.4-1.10.5
Condit. Reinf. lever presses0.81.13.10.1-0.50.2-0.2-1.0-0.01.01.3-1.41.3-1.3-0.90.8-1.60.5-1.0-1.81.2
Condit. Reinf. active minus inactive responses0.81.04.4-0.3-0.1-0.2-0.21.40.2-1.70.3-0.6-0.90.12.1-2.10.3-0.90.80.3-1.4
Condit. Reinf. active-inactive response ratio1.11.23.1-1.10.60.40.50.90.9-1.3-0.2-0.5-1.30.61.7-1.80.4-1.51.30.5-1.5
Condit. Reinf. active responses0.40.52.40.1-0.4-0.4-0.31.1-0.0-1.20.6-0.6-0.4-0.21.5-1.50.0-0.30.3-0.1-0.9
Condit. Reinf. inactive responses1.01.22.91.6-1.5-1.2-1.30.3-1.30.11.1-0.11.3-1.3-0.20.1-0.61.7-1.5-0.80.8
Condit. Reinf. lever presses0.71.03.01.0-1.2-1.2-1.01.4-0.6-1.31.0-0.40.1-0.81.7-1.7-0.10.3-0.4-0.5-0.6
Condit. Reinf. lever reinforcers received0.40.52.1-0.2-0.1-0.1-0.00.90.3-1.00.6-0.9-0.6-0.21.4-1.4-0.1-0.50.4-0.2-0.9
Conditioned reinforcement - actives1.81.85.70.20.3-0.5-0.91.1-1.2-1.5-1.52.4-1.31.50.7-0.72.10.91.02.3-0.9
Conditioned reinforcement - inactives1.01.13.2-0.61.10.30.5-0.00.1-0.5-1.81.8-1.31.7-0.50.61.5-0.30.91.7-0.2
Conditioned locomotion0.10.20.7-0.00.40.2-0.2-0.0-0.4-0.4-0.20.5-0.80.4-0.30.30.50.70.40.6-0.2
Patch foraging indifference point 0 sec1.01.65.1-0.20.1-0.3-0.22.10.0-1.7-0.40.7-1.40.82.3-2.21.4-0.91.20.8-2.0
Patch foraging indifference point AUC0.50.52.00.5-0.4-1.1-0.61.0-0.7-1.4-0.71.20.00.60.7-0.70.90.10.3-0.1-0.2
Delay disc. indifference point, 0s delay0.70.82.31.0-0.8-1.2-0.9-0.1-1.2-0.5-0.51.50.70.0-1.01.00.41.3-0.60.21.2
Delay disc. indifference point, 16s delay3.23.27.8-2.62.82.52.4-1.12.21.2-1.60.2-2.21.9-0.50.61.0-1.92.11.8-1.0
Delay disc. indifference point, 2s delay2.22.46.02.4-2.2-2.4-2.41.3-2.4-1.40.21.31.5-0.90.5-0.50.32.1-1.30.30.7
Delay disc. indifference point, 24s delay1.81.84.0-1.72.01.92.0-1.61.71.7-1.0-0.2-1.11.0-1.31.40.1-1.01.00.50.2
Delay disc. indifference point, 4s delay1.01.04.30.10.4-0.5-0.40.6-0.7-0.7-1.62.1-0.41.3-0.10.21.70.70.72.1-0.1
Delay disc. indifference point, 8s delay0.40.41.30.50.1-0.2-0.6-0.1-0.80.5-0.61.00.30.3-0.70.70.61.0-0.11.10.5
Indifference point function ln k0.20.31.20.7-0.6-0.5-1.00.7-0.8-0.50.30.30.3-0.20.4-0.40.20.4-0.31.1-0.4
Indifference point function log k0.20.31.20.7-0.6-0.5-1.00.7-0.8-0.50.30.30.3-0.20.4-0.40.20.4-0.31.1-0.4
Patch foraging total patch changes 0 sec1.21.95.9-0.20.1-0.3-0.32.20.1-1.9-0.30.6-1.50.82.4-2.41.4-1.01.20.8-2.2
Patch foraging total patch changes 12 sec0.10.20.80.0-0.3-0.20.10.50.1-0.70.4-0.2-0.2-0.20.8-0.8-0.1-0.30.1-0.9-0.2
Patch foraging total patch changes 18 sec0.40.51.3-0.60.60.20.40.40.4-0.9-1.10.8-0.81.00.5-0.41.0-0.70.80.0-0.5
Patch foraging total patch changes 24 sec0.81.02.70.4-0.2-0.7-0.41.6-0.3-1.4-0.60.9-0.80.61.6-1.61.2-0.20.90.7-1.2
Patch foraging total patch changes 6 sec3.04.48.8-1.81.80.61.21.81.2-1.7-2.31.7-3.02.72.0-2.02.7-2.32.82.0-2.6
Patch foraging time to switch 0 sec2.23.59.6-1.10.62.11.7-3.01.53.11.3-2.50.5-1.4-2.12.1-2.5-0.1-0.8-1.61.9
Patch foraging water rate 0 sec0.20.31.20.5-0.4-0.9-0.81.1-0.5-0.80.00.40.2-0.00.6-0.60.40.2-0.2-0.4-0.5
Patch foraging water rate 12 sec1.52.36.90.8-0.4-1.4-1.32.6-1.0-1.9-0.81.4-0.90.82.2-2.21.90.01.11.8-2.1
Patch foraging water rate 18 sec0.50.72.60.4-0.2-0.6-0.71.5-0.3-0.9-0.00.4-0.70.21.5-1.50.80.10.80.2-1.6
Patch foraging water rate 24 sec0.71.02.41.1-0.5-1.3-1.41.4-1.3-1.3-0.71.60.10.60.5-0.41.20.7-0.11.3-0.7
Patch foraging water rate 6 sec0.91.44.4-0.20.7-0.4-0.31.2-0.3-1.6-1.61.7-0.81.70.5-0.51.7-0.71.02.1-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.30.20.0-0.1-0.40.4-0.3-0.5-0.30.1-0.00.30.1-0.00.30.10.10.5-0.5
Distance traveled before self-admin0.70.72.40.80.1-0.6-1.00.4-1.1-0.4-1.41.50.10.9-0.50.51.11.20.21.20.1
Distance traveled after self-admin1.51.74.82.0-1.5-2.0-2.00.9-2.2-0.6-0.21.51.4-0.4-0.20.20.51.8-1.10.60.9
Extensor digitorum longus weight2.810.928.55.3-4.9-4.7-4.61.7-4.7-0.92.41.34.1-3.0-0.0-0.0-0.84.5-3.7-0.82.5
Bone: elastic displacement0.91.02.2-1.11.20.70.90.40.8-0.3-1.50.8-1.31.50.4-0.31.3-0.91.41.2-1.0
Bone: elastic work0.20.30.80.4-0.4-0.7-0.60.9-0.6-0.8-0.30.70.20.30.4-0.40.70.50.00.8-0.3
Bone: endosteal estimation1.22.75.72.3-2.4-1.9-2.00.8-1.8-0.82.2-0.61.8-2.00.6-0.6-1.21.7-2.0-1.70.9
Bone: endosteal perimeter1.22.55.32.0-2.0-1.5-1.5-0.1-1.50.11.9-0.52.0-2.0-0.50.5-1.51.8-2.3-1.91.7
Epididymis fat weight0.51.13.60.7-1.0-1.1-1.01.7-0.7-1.70.8-0.20.2-0.41.9-1.90.30.10.3-0.1-1.0
Delta time in closed arm before/after self-admin1.61.65.40.0-0.30.60.7-1.60.52.31.7-1.50.9-1.4-1.11.1-1.70.1-1.1-1.61.4
Delta time in open arm before/after self-admin1.61.67.10.9-1.0-1.6-1.22.0-1.1-2.7-0.51.20.20.31.6-1.61.0-0.10.00.9-0.9
Diff in mean of infusions in LGA sessions1.51.74.1-1.41.50.90.70.61.0-1.5-1.40.1-2.01.61.0-1.01.1-1.61.80.9-1.7
Delay discount exponential model param0.30.31.40.2-0.6-0.4-0.20.2-0.0-0.40.8-0.70.4-0.60.4-0.4-0.7-0.3-0.5-1.2-0.0
Extinction: sum of active levers before priming0.30.30.8-0.70.60.60.9-0.80.80.4-0.4-0.1-0.10.3-0.60.6-0.2-0.70.0-0.20.4
Active lever presses in extinction session 60.60.61.9-0.80.70.40.60.70.8-0.7-0.4-0.1-1.40.60.9-0.90.5-1.21.20.2-1.0
Bone: final force2.94.711.93.2-3.1-3.5-3.22.5-3.1-2.51.31.32.0-1.21.5-1.50.42.0-1.80.60.2
Bone: final moment2.43.99.72.8-2.8-3.1-2.92.5-2.7-2.51.11.21.6-1.01.7-1.70.51.7-1.30.6-0.2
Food consumed during 24 hour testing period1.01.23.01.5-1.5-1.7-1.61.1-1.6-1.40.41.01.2-0.40.3-0.30.31.1-1.3-0.00.4
Glucose0.71.02.6-0.50.7-0.0-0.11.10.0-1.0-1.51.2-1.21.40.9-0.91.6-0.41.41.2-1.2
Heart weight0.60.92.4-0.50.90.00.40.80.3-0.7-1.31.2-0.71.50.6-0.61.4-1.11.11.3-1.0
Delay discount hyperbolic model param0.30.31.4-0.0-0.4-0.00.10.00.3-0.20.8-1.00.3-0.60.3-0.3-0.8-0.5-0.4-1.2-0.1
Intermittent access intake day 1-15 change1.11.14.2-0.10.60.60.4-1.60.11.5-1.10.60.50.6-2.02.0-0.20.2-0.80.21.5
Intermittent access intake escalation0.90.83.2-0.10.60.50.3-1.40.11.3-1.20.80.40.7-1.81.80.00.1-0.70.41.2
Intermittent access intake escalation 21.11.14.2-0.40.70.60.7-1.60.31.8-0.90.60.50.6-2.02.0-0.2-0.2-0.70.21.4
Intermitt. access day 1 inactive lever presses0.40.41.90.00.60.2-0.1-0.2-0.4-0.5-1.01.4-0.40.9-0.50.50.90.20.31.10.1
Intermitt. access day 15 inactive lever presses0.50.61.61.2-0.9-0.9-1.00.2-1.2-0.20.10.70.7-0.4-0.50.5-0.01.2-0.80.10.8
Intermitt. access escalation Index0.40.40.90.7-0.8-0.8-0.80.6-0.6-0.90.4-0.21.0-0.40.4-0.4-0.30.3-0.7-0.3-0.0
Intermittent access day 1 total infusions1.31.56.00.6-0.7-1.0-0.92.1-0.6-2.40.10.2-1.3-0.12.0-2.00.80.30.70.5-1.5
Intermittent access day 15 total infusions0.30.30.80.00.0-0.3-0.30.7-0.2-0.9-0.90.7-0.90.60.4-0.40.70.00.30.7-0.5
Intermittent access terminal intake (last 3 days)0.30.30.8-0.00.1-0.3-0.30.8-0.2-0.9-0.80.6-0.90.60.5-0.50.8-0.10.40.7-0.7
Intermittent access total infusions1.01.13.20.5-0.5-0.8-1.01.8-0.8-1.7-0.50.7-1.10.41.5-1.51.00.50.60.8-1.3
Intermittent access day 1 locomotion1.51.68.40.3-0.4-0.9-0.62.1-0.3-2.9-0.20.3-1.30.22.0-2.00.9-0.20.80.5-1.6
Intermittent access day 15 total locomotion3.03.27.8-2.31.91.11.50.61.6-1.8-2.10.9-2.82.40.9-0.81.7-2.22.21.7-1.9
Intermittent access total locomotion1.92.19.0-0.80.3-0.3-0.02.00.4-3.0-0.80.0-2.11.02.2-2.21.1-1.11.40.6-2.1
Intermittent access standard deviation0.30.31.60.6-0.2-0.4-0.4-0.1-0.60.1-0.71.30.10.4-0.60.60.50.4-0.50.80.6
Left kidney weight1.85.011.63.2-3.0-3.4-3.42.9-3.1-2.90.71.61.7-0.91.7-1.70.72.1-1.20.5-0.5
Right kidney weight2.05.813.23.5-3.3-3.6-3.63.1-3.5-2.91.01.71.8-1.21.9-1.90.82.5-1.30.6-0.4
Cocaine induced anxiety0.20.20.7-0.50.30.40.4-0.30.6-0.5-0.3-0.70.10.1-0.20.2-0.5-0.9-0.1-0.60.1
Post-drug Anxiety0.70.71.9-0.81.00.50.10.30.3-0.8-1.40.8-1.01.30.5-0.41.1-0.61.21.2-0.9
Baseline Anxiety1.21.35.00.8-0.2-0.9-1.01.2-1.4-0.7-0.82.2-0.51.00.6-0.51.91.20.82.0-0.7
Tail length1.34.09.13.0-2.6-3.0-2.82.9-2.7-2.00.91.40.9-1.02.0-2.01.02.1-0.80.8-1.0
Length with tail0.31.12.61.6-1.1-1.6-1.31.6-1.4-1.00.21.50.5-0.10.6-0.61.01.0-0.20.9-0.4
Length without tail0.40.82.3-0.71.20.91.0-1.00.71.3-0.90.9-0.10.9-1.51.50.5-0.40.50.60.4
Times rat made contact with spout1.72.04.61.9-1.7-1.6-1.70.1-1.9-0.30.50.82.1-1.0-1.01.0-0.51.7-2.00.71.8
Lifetime Intake1.41.65.01.0-0.9-1.3-1.52.2-1.2-2.0-0.20.7-0.90.11.8-1.81.10.90.50.8-1.4
Liver weight, left0.20.31.00.4-0.6-0.3-0.40.6-0.1-0.31.0-0.60.1-0.60.9-0.9-0.40.1-0.1-0.7-0.4
Liver weight, right1.01.65.60.9-1.3-0.4-0.5-0.2-0.20.42.4-1.90.9-2.10.2-0.3-2.00.5-1.1-2.10.8
Locomotor activity0.10.20.90.0-0.10.10.50.00.60.10.9-0.6-0.2-0.60.6-0.6-0.5-0.7-0.1-0.5-0.2
Locomotor testing distance0.20.31.70.1-0.3-0.40.10.80.2-0.60.5-0.0-0.3-0.21.3-1.30.2-0.70.2-0.0-0.7
Locomotor testing rearing0.30.41.3-0.30.10.30.50.30.8-0.10.8-1.0-0.5-0.41.1-1.1-0.4-0.80.4-0.3-0.8
Locomotion in novel chamber0.60.83.40.2-0.5-0.6-0.61.7-0.2-1.20.3-0.5-0.4-0.11.8-1.80.1-0.50.40.2-1.2
Locomotion in novel chamber post-restriction1.21.43.9-1.21.10.50.81.01.2-0.9-0.9-0.2-1.81.21.5-1.50.8-2.01.60.5-1.6
Fecal boli incidents, locomotor time 10.91.05.1-0.20.00.70.5-0.90.81.01.3-2.30.1-1.3-0.20.1-1.70.3-0.5-1.60.4
Change in fecal boli incidents, locomotor task2.92.87.30.20.5-0.5-0.72.5-0.8-1.5-1.72.3-1.61.91.9-1.72.70.11.91.9-2.1
Time >=10cm from walls, locomotor time 10.60.61.71.3-0.9-1.3-1.20.8-1.2-0.7-0.40.80.8-0.1-0.10.10.31.0-0.60.40.2
Bouts of movement, locomotor time 11.71.94.7-2.11.82.12.1-1.62.20.6-0.4-1.4-1.10.6-0.90.9-0.8-1.90.7-0.40.1
Total resting periods, locomotor time 12.02.15.2-2.11.92.22.3-1.82.31.1-0.1-1.6-1.10.4-1.11.1-0.9-1.70.7-0.50.3
Rest time, locomotor task time 10.91.03.8-0.20.60.80.8-1.40.41.90.0-0.00.2-0.1-1.91.9-0.40.8-0.2-0.11.4
Distance moved, locomotor task time 11.11.24.10.3-0.8-1.0-0.81.6-0.6-2.0-0.10.6-0.20.32.0-2.00.8-1.00.30.4-1.3
Vertical activity count, locomotor time 11.81.96.81.0-1.2-1.9-1.61.8-1.5-2.6-0.92.00.50.81.1-1.11.4-0.4-0.21.5-0.7
Time >=10cm from walls, locomotor time 21.61.74.22.0-1.8-2.0-1.91.2-2.1-0.80.31.11.5-0.70.0-0.10.32.1-1.1-0.10.4
Bouts of movement, locomotor time 22.02.27.00.4-1.2-0.00.2-0.90.50.72.4-2.60.7-2.4-0.30.2-2.60.3-1.3-2.61.4
Total resting periods, locomotor time 21.92.05.80.7-1.3-0.3-0.1-0.70.20.62.4-2.40.7-2.4-0.20.1-2.40.4-1.3-2.41.3
Rest time, locomotor task time 20.20.20.50.30.1-0.1-0.20.7-0.3-0.1-0.50.6-0.40.30.3-0.30.70.70.50.7-0.5
Distance moved, locomotor task time 20.50.51.40.6-0.8-0.9-0.7-0.2-0.9-0.6-0.11.01.20.0-1.01.00.10.2-0.9-0.20.9
Vertical activity count, locomotor time 20.91.04.60.5-0.3-1.2-0.60.8-1.0-1.3-1.22.10.41.1-0.50.61.3-0.4-0.11.30.0
Light reinforcement 10.40.71.5-0.80.70.80.80.41.0-0.10.3-0.8-1.20.21.1-1.10.1-1.11.20.1-1.1
Light reinforcement 20.40.61.6-0.50.30.30.30.80.6-0.70.4-0.5-1.10.21.3-1.30.2-0.91.10.2-1.2
Bone: marrow area1.12.45.12.2-2.3-1.8-1.80.6-1.7-0.72.1-0.61.8-2.00.5-0.5-1.21.6-2.0-1.70.9
Bone: maximum diameter1.22.25.12.3-2.2-2.2-2.01.4-2.0-1.31.50.41.4-1.30.9-0.9-0.31.5-1.4-0.70.3
Bone: maximum force2.44.110.33.0-2.9-3.2-2.92.3-2.9-2.31.21.41.9-1.11.2-1.30.52.0-1.70.50.3
Bone: maximum moment1.93.38.12.6-2.5-2.8-2.62.3-2.6-2.31.01.31.5-0.81.4-1.40.61.7-1.30.5-0.1
Mean time between licks in bursts0.40.51.8-0.1-0.10.40.3-0.90.40.60.8-1.20.6-0.8-0.60.5-1.3-0.1-1.1-0.80.9
Mean num. licks in bursts3.74.410.03.1-3.0-3.2-3.02.8-2.8-2.31.31.01.6-1.32.0-2.00.52.0-1.10.2-0.5
Cd content in liver3.74.08.6-2.92.82.72.7-0.52.70.7-1.3-0.5-2.81.80.5-0.50.9-2.52.81.0-1.8
Co content in liver1.82.14.4-1.41.50.70.80.80.7-0.8-2.01.3-1.62.10.8-0.71.9-1.32.02.1-1.6
Cu content in liver0.91.12.8-0.30.2-0.5-0.21.4-0.1-1.5-1.31.0-0.81.11.4-1.31.3-0.80.91.7-1.4
Fe content in liver1.11.35.0-1.01.40.70.7-0.20.5-0.3-2.01.2-0.71.7-0.60.71.2-0.91.22.2-0.4
K content in liver0.10.10.4-0.3-0.1-0.0-0.00.10.1-0.60.2-0.60.0-0.10.4-0.4-0.3-0.4-0.1-0.6-0.2
Mg content in liver0.80.84.3-0.50.00.70.5-0.50.90.11.3-2.1-0.1-1.00.5-0.6-1.4-0.7-0.3-1.4-0.0
Mn content in liver0.50.61.40.8-0.8-0.4-0.6-0.5-0.60.51.0-0.61.2-1.0-0.60.5-0.90.8-1.0-0.51.0
Na content in liver4.34.59.42.9-3.0-2.5-2.60.1-2.4-0.52.3-0.53.0-2.5-0.50.4-1.82.4-3.1-1.52.0
Rb content in liver2.63.36.7-1.71.81.21.11.21.3-0.9-1.70.3-2.62.02.0-1.91.7-2.12.62.0-2.6
Se content in liver0.20.31.10.3-0.4-0.4-0.5-0.4-0.5-0.40.10.11.0-0.2-0.70.7-0.30.4-0.5-0.10.8
Sr content in liver0.30.30.80.7-0.9-0.8-0.50.4-0.5-0.40.8-0.20.5-0.70.3-0.3-0.40.3-0.5-0.40.2
Zn content in liver1.41.54.11.7-2.0-1.7-1.41.0-1.1-0.91.6-0.71.0-1.61.1-1.2-0.90.7-1.3-0.50.3
Bone: minimum diameter1.32.45.62.3-2.4-2.0-2.00.9-1.9-0.81.60.11.8-1.70.4-0.5-0.72.0-1.9-1.20.9
Time in familiar zone, hab. session 11.51.44.4-1.11.30.40.70.30.6-0.8-2.11.3-1.31.90.2-0.11.5-1.21.31.4-1.0
Time in novel zone, hab. session 11.61.54.91.2-1.5-0.5-0.6-0.1-0.51.42.2-1.31.4-2.20.0-0.1-1.41.5-1.1-1.40.8
Total zone transitions, hab. session 11.62.25.81.5-1.5-2.2-1.82.4-1.8-2.0-0.51.80.20.31.6-1.61.61.00.20.8-1.0
Total locomotion distance, hab. session 13.14.411.92.3-2.2-3.0-2.53.4-2.3-2.9-0.11.90.10.02.8-2.81.81.00.11.5-1.7
Locomotion velocity, hab. session 12.53.69.92.0-1.9-2.6-2.23.2-2.0-2.70.01.4-0.10.02.8-2.81.50.60.11.3-1.7
Time in familiar zone, hab. session 20.30.31.10.6-0.4-0.7-0.60.6-0.7-1.1-0.40.70.20.20.4-0.40.50.3-0.10.1-0.2
Time in novel zone, hab. session 20.10.10.3-0.40.10.40.4-0.00.50.40.4-0.5-0.3-0.20.2-0.2-0.2-0.50.20.3-0.3
Total zone transitions, hab. session 21.31.75.31.2-1.3-1.8-1.52.3-1.3-1.7-0.01.2-0.10.11.8-1.81.20.70.10.2-1.2
Total locomotion distance, hab. session 21.92.56.51.7-1.6-2.3-1.82.6-1.8-2.0-0.41.8-0.00.21.9-1.91.60.9-0.01.2-1.3
Locomotion velocity, hab. session 22.02.76.71.9-1.9-2.5-2.02.6-2.0-2.1-0.11.70.2-0.01.9-1.91.41.0-0.30.8-1.1
Novel to familiar place preference ratio0.60.61.6-1.11.20.80.9-0.60.70.3-1.30.4-0.41.1-0.60.60.4-1.00.50.80.0
Novelty place preference0.70.72.2-1.11.20.70.8-0.70.60.4-1.50.6-0.41.2-0.90.90.5-0.80.51.00.1
Time in novel zone, NPP test0.70.72.2-1.11.20.70.9-0.40.70.2-1.50.5-0.61.3-0.50.50.6-1.10.71.0-0.2
Total zone transitions, NPP test0.81.23.21.4-1.3-1.7-1.41.8-1.4-1.20.11.10.2-0.11.3-1.20.90.80.00.4-0.7
Total locomotion distance, NPP test1.11.53.61.4-1.2-1.9-1.41.8-1.5-1.6-0.51.60.20.41.1-1.11.20.5-0.31.2-0.7
Locomotion velocity, NPP test1.01.43.11.4-1.1-1.8-1.61.6-1.6-1.5-0.51.60.20.40.9-0.91.20.8-0.31.1-0.6
Intraocular pressure0.20.31.10.6-0.8-0.4-0.40.2-0.30.51.1-0.70.4-1.00.5-0.5-0.60.4-0.7-0.40.2
Delta distance traveled before/after self-admin0.80.92.51.2-1.6-1.2-1.10.7-1.0-0.11.2-0.31.1-1.40.5-0.6-0.60.8-1.1-0.70.6
Delta ambulatory time before/after self-admin0.60.71.91.2-1.4-1.1-1.10.7-1.1-0.30.90.11.0-1.10.4-0.5-0.30.9-1.0-0.30.5
Parametrial fat weight1.52.88.91.4-1.8-2.2-2.12.8-1.8-3.00.11.20.20.02.3-2.31.20.80.00.7-1.4
Pavlov. Cond. lever latency3.03.810.8-1.41.90.41.00.80.6-1.0-3.32.9-2.03.10.3-0.23.0-1.32.42.8-1.7
Pavlov. Cond. magazine entry latency3.64.612.52.1-2.6-1.2-1.80.0-1.3-0.03.5-2.82.5-3.40.6-0.7-2.91.7-2.4-2.51.4
Pavlov. Cond. change in total contacts5.15.511.62.0-2.1-0.6-1.2-1.4-1.11.53.4-2.63.1-3.4-1.31.2-3.41.9-3.1-2.92.8
Pavlov. Cond. index score4.05.014.81.7-2.3-0.6-1.2-0.8-0.80.83.9-3.32.5-3.6-0.1-0.0-3.51.4-2.6-3.11.9
Pavlov. Cond. latency score3.34.112.41.5-2.1-0.6-1.2-0.6-0.70.63.5-3.12.2-3.3-0.0-0.1-3.21.3-2.3-2.71.7
Pavlov. Cond. lever contacts4.45.213.61.8-2.3-0.7-1.4-0.8-0.90.93.7-3.12.6-3.6-0.40.2-3.41.7-2.8-3.22.1
Pavlov. Cond. magazine entry number4.15.113.9-1.82.30.71.21.01.0-1.0-3.73.0-2.73.50.5-0.43.4-1.72.73.1-2.2
Pavlov. Cond. intertrial magazine entries2.22.75.8-1.82.00.91.40.71.3-0.7-2.11.4-2.22.40.7-0.62.1-1.92.01.5-1.8
Pavlov. Cond. lever-magazine prob. diff.4.45.516.21.8-2.5-0.8-1.4-0.6-0.90.64.0-3.42.6-3.7-0.0-0.1-3.61.5-2.8-3.11.9
Pavlov. Cond. response bias5.16.215.72.0-2.4-0.7-1.4-1.2-1.01.34.0-3.23.0-3.9-0.80.6-3.71.9-3.1-3.32.6
Pavlov. Cond. lever latency0.50.71.8-1.01.01.11.1-1.30.81.3-0.5-0.0-0.20.5-1.21.3-0.1-0.40.40.30.7
Pavlov. Cond. magazine entry latency1.21.43.7-0.60.61.30.9-1.90.91.50.6-1.50.5-0.7-1.61.6-1.50.0-0.8-1.21.3
Pavlov. Cond. change in total contacts0.91.23.7-0.80.80.30.41.10.7-1.4-0.70.0-1.61.01.6-1.61.0-1.11.30.2-1.9
Pavlov. Cond. index score0.10.10.6-0.20.10.30.1-0.20.4-0.20.4-0.8-0.1-0.30.2-0.2-0.5-0.2-0.2-0.7-0.1
Pavlov. Cond. latency score0.10.10.50.1-0.10.1-0.0-0.20.1-0.10.5-0.70.1-0.40.0-0.1-0.50.1-0.5-0.70.1
Pavlov. Cond. lever contacts0.60.92.11.1-1.2-1.1-1.11.2-0.8-1.21.0-0.40.4-0.81.4-1.4-0.20.5-0.5-0.6-0.6
Pavlov. Cond. magazine entry number0.91.13.31.5-1.5-1.8-1.51.4-1.5-1.00.31.00.7-0.40.9-0.90.50.8-0.50.6-0.1
Pavlov. Cond. intertrial magazine entries1.31.73.81.6-2.0-1.8-1.61.5-1.4-1.21.3-0.21.0-1.31.6-1.6-0.30.8-1.1-0.5-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.9-0.30.20.50.3-0.50.50.10.5-1.0-0.1-0.4-0.0-0.0-0.7-0.2-0.3-0.90.0
Pavlov. Cond. response bias0.10.20.60.1-0.2-0.0-0.20.30.1-0.60.6-0.8-0.0-0.40.7-0.7-0.4-0.1-0.2-0.5-0.4
Time in closed arm before self-admin0.70.82.70.9-0.6-1.1-1.11.5-1.0-1.6-0.80.9-0.20.40.8-0.80.90.40.20.8-0.7
Time in closed arm after self-admin1.11.12.9-1.11.41.00.90.10.90.4-1.10.4-1.71.40.3-0.31.1-1.11.61.1-1.2
Time in open arm before self-admin1.31.43.6-1.41.31.71.5-1.91.41.90.3-1.1-0.40.0-1.31.3-0.9-0.70.2-0.90.6
Time in open arm after self-admin1.01.13.01.3-1.5-1.5-1.10.3-1.1-1.00.60.41.7-0.9-0.20.1-0.60.6-1.7-0.51.1
Bone: periosteal estimation1.93.98.93.0-3.0-2.8-2.81.6-2.6-1.51.90.42.1-1.90.9-1.0-0.52.3-2.1-1.10.7
Bone: periosteal perimeter1.11.84.11.8-2.0-1.7-1.60.9-1.5-0.71.7-0.31.4-1.60.7-0.7-0.81.5-1.5-1.40.6
Bone: post-yield work1.41.95.91.5-1.6-1.5-1.41.9-1.0-1.61.6-0.50.1-1.22.4-2.4-0.10.5-0.4-0.6-1.1
Progressive ratio test 1 active lever presses0.60.63.50.3-0.3-0.6-0.41.4-0.1-1.9-0.0-0.3-0.9-0.01.2-1.20.3-0.10.4-0.1-1.0
Progressive ratio test 1 breakpoint0.60.63.10.3-0.3-0.6-0.41.3-0.1-1.80.0-0.3-0.9-0.11.2-1.20.3-0.10.5-0.1-1.0
Progressive ratio test 1 inactive lever presses0.40.53.70.7-0.5-0.9-0.71.1-0.5-1.9-0.10.1-0.5-0.10.7-0.70.20.3-0.10.0-0.4
Progressive ratio test 2 active lever presses0.60.72.10.3-0.1-0.5-0.61.4-0.4-1.4-0.00.0-1.30.11.3-1.20.60.40.80.4-1.2
Progressive ratio test 2 breakpoint0.60.72.00.2-0.1-0.4-0.61.4-0.3-1.4-0.0-0.1-1.40.11.3-1.30.60.30.80.3-1.3
Progressive ratio test 2 inactive lever presses0.50.62.5-0.30.3-0.1-0.01.10.2-1.5-0.3-0.1-1.60.41.1-1.10.6-0.40.90.3-1.2
Incentive Sensitization - Responses0.20.20.90.2-0.10.0-0.40.5-0.20.20.7-0.9-0.6-0.50.5-0.5-0.30.60.2-0.6-0.5
Incentive Sensitization - Breakpoint0.20.20.70.1-0.10.0-0.40.6-0.20.10.6-0.9-0.7-0.50.6-0.6-0.20.50.3-0.5-0.6
Sum of active levers in priming session hrs 5-60.50.41.5-0.60.10.60.50.00.8-0.00.8-1.2-0.5-0.50.7-0.7-0.7-1.00.3-0.9-0.5
Progressive ratio1.01.13.1-0.60.80.40.20.90.3-0.8-0.90.6-1.61.21.3-1.31.3-0.71.81.2-1.4
Food seeking constrained by brief footshock0.70.92.5-1.41.61.01.2-0.91.00.2-1.10.4-0.41.3-0.70.80.6-1.10.90.7-0.4
Seeking ratio, punishment vs. effort0.70.82.60.5-0.7-0.4-0.3-0.8-0.30.40.9-0.71.6-1.1-0.90.9-1.10.6-1.5-1.01.0
Retroperitoneal fat weight0.72.28.4-0.50.1-0.3-0.12.20.3-1.70.3-0.2-1.40.52.9-2.91.0-1.21.80.4-2.5
Reaction time number correct0.50.72.2-1.10.91.21.3-0.71.51.00.1-1.0-0.9-0.1-0.20.1-0.5-1.10.5-0.3-0.2
Reaction time mean minus median0.10.10.6-0.2-0.2-0.30.10.2-0.0-0.8-0.60.2-0.10.40.1-0.10.2-0.40.1-0.1-0.1
Reaction time mean minus median AUC0.50.71.7-1.00.60.40.80.40.9-0.8-1.0-0.1-1.10.90.7-0.70.5-1.31.00.3-1.0
Reaction time num false alarms0.60.93.0-0.90.90.60.9-1.50.50.7-1.00.60.30.8-1.71.7-0.0-0.7-0.20.11.0
Reaction time num false alarms AUC0.50.72.2-0.70.70.60.9-1.50.60.9-0.4-0.00.40.2-1.41.5-0.5-0.5-0.4-0.41.0
Reaction time trials correct on left0.50.72.2-1.10.91.21.3-0.71.51.00.1-1.0-0.9-0.1-0.20.1-0.5-1.10.5-0.3-0.2
Reaction time trials on left0.50.72.3-1.10.91.21.3-0.71.51.00.2-1.1-0.9-0.1-0.10.1-0.5-1.10.5-0.4-0.3
Reaction time mean0.20.20.70.3-0.5-0.4-0.40.7-0.4-0.80.0-0.2-0.1-0.10.8-0.80.00.0-0.1-0.6-0.6
Reaction time mean AUC0.10.20.70.1-0.4-0.1-0.10.3-0.1-0.30.3-0.6-0.1-0.30.6-0.6-0.3-0.0-0.2-0.9-0.4
Median of all reaction times0.20.30.80.5-0.6-0.4-0.50.6-0.4-0.50.4-0.40.0-0.40.9-0.9-0.20.2-0.2-0.8-0.5
Reaction time omissions0.70.93.6-0.60.00.90.9-1.11.11.21.0-1.90.2-1.0-0.20.1-1.5-0.6-0.4-1.60.2
Reaction time false alarm rate0.40.62.20.00.1-0.1-0.0-1.1-0.40.5-0.50.61.00.2-1.51.5-0.20.2-0.8-0.11.3
Reaction time premature initiation rate1.01.43.21.7-1.7-1.6-1.50.3-1.8-0.40.70.61.7-1.1-0.30.3-0.31.6-1.30.51.1
Reaction time premature initiations0.50.71.51.0-1.1-0.7-0.6-0.3-0.80.50.8-0.01.2-1.2-0.60.6-0.71.0-1.00.31.1
Std. dev. reaction times0.10.20.70.1-0.3-0.4-0.20.7-0.2-0.8-0.40.1-0.30.20.8-0.80.4-0.20.2-0.0-0.7
Reaction time trials completed0.50.72.3-1.10.91.21.3-0.71.51.00.2-1.1-0.9-0.1-0.10.1-0.5-1.10.5-0.4-0.3
Reaction time trials AUC0.40.51.7-1.00.71.01.1-0.51.30.80.1-0.9-0.8-0.1-0.00.0-0.4-1.00.5-0.2-0.3
Run reversals in cocaine runway, females3.93.89.53.0-2.6-2.8-2.91.5-3.1-1.80.51.82.3-0.90.5-0.50.62.5-1.70.70.8
Run reversals in cocaine runway, males0.30.30.9-0.30.60.50.5-0.60.40.7-0.80.4-0.40.5-0.80.80.2-0.30.20.9-0.0
Latency to leave start box in cocaine runway1.11.23.7-0.90.90.20.70.90.9-0.4-0.90.4-1.61.11.2-1.11.2-1.21.31.2-1.9
Latency to leave start box in cocaine runway, F0.30.31.0-0.60.40.40.7-0.21.00.80.4-1.0-0.4-0.20.3-0.3-0.4-0.80.0-0.5-0.8
Latency to leave start box in cocaine runway, M2.42.35.8-0.81.10.20.41.30.3-1.1-1.91.6-2.02.01.1-1.12.3-0.82.12.4-2.0
Std. dev. time between licks in bursts0.50.52.0-0.2-0.40.10.0-0.30.2-0.41.2-1.40.4-0.90.2-0.2-1.3-0.4-0.9-1.40.4
Total sessions with >9 infusions3.33.69.42.8-2.2-2.5-3.12.4-3.0-2.00.31.60.6-0.71.4-1.41.02.8-0.71.0-0.4
Short access day 1 total inactive lever presses0.40.51.50.30.3-0.1-0.30.7-0.3-0.8-0.70.9-1.20.60.7-0.71.00.30.71.0-0.8
Short access day 10 total inactive lever presses0.70.82.1-0.61.20.80.6-0.90.20.0-1.51.3-0.61.2-1.01.00.9-0.20.51.20.2
Short access day 1 total infusions1.92.04.31.4-0.7-1.3-1.82.1-1.8-1.6-0.31.5-0.70.31.7-1.71.61.60.61.5-1.3
Short access day 10 total infusions1.11.22.81.5-1.3-1.4-1.61.6-1.5-1.70.10.7-0.0-0.41.0-1.00.51.4-0.30.4-0.4
Short access total infusions2.22.57.21.5-1.2-1.7-2.02.7-1.8-2.2-0.11.1-0.7-0.02.2-2.21.41.40.51.1-1.6
Short access day 1 locomotion0.70.71.80.7-0.1-0.5-1.00.9-1.1-0.8-0.61.3-0.50.60.7-0.71.31.00.51.3-0.7
Short access day 10 total locomotion1.11.24.11.1-1.3-1.3-1.21.7-0.8-2.00.6-0.6-0.2-0.81.7-1.7-0.30.2-0.4-0.7-0.6
Short access total locomotion2.62.78.10.5-0.5-1.1-1.22.8-0.8-2.6-0.50.9-1.60.62.8-2.81.60.11.31.2-2.3
One hour access (0.3 mA shock)1.31.66.50.8-1.2-1.3-1.42.1-0.9-2.60.3-0.4-0.6-0.42.0-2.00.10.30.0-0.3-1.3
Compulsive drug intake0.70.72.7-0.3-0.30.0-0.00.60.4-0.41.3-1.7-0.2-0.81.4-1.4-0.8-0.60.2-1.2-0.8
One hour access (shock baseline)0.50.61.7-0.60.60.10.40.50.3-0.9-1.30.9-1.11.10.1-0.01.0-0.70.71.0-0.6
Social response proportion0.80.92.3-1.30.70.71.10.41.4-0.40.1-0.7-1.20.41.0-1.00.1-1.51.0-0.9-1.2
Social responses0.91.13.2-1.50.91.21.6-0.61.80.40.6-1.4-0.9-0.00.1-0.1-0.7-1.50.5-1.7-0.3
Social time0.91.23.2-1.71.51.61.8-0.71.80.5-0.5-0.4-1.30.9-0.10.20.3-1.41.1-0.4-0.6
Soleus weight1.33.98.62.6-2.0-2.9-2.72.7-2.9-2.3-0.42.60.90.31.5-1.41.81.7-0.52.1-0.8
Bone: stiffness2.03.28.42.6-2.4-2.9-2.61.7-2.8-2.10.51.81.7-0.60.6-0.60.61.9-1.50.80.5
Tibialis anterior weight3.411.829.45.3-4.8-5.4-5.33.9-5.2-2.91.42.63.0-1.82.1-2.11.04.0-2.10.90.3
Time to tail flick, vehicle, before self-admin0.20.20.70.2-0.6-0.50.1-0.4-0.00.30.6-0.10.6-0.5-0.30.3-0.5-0.2-0.8-0.40.6
Time to tail flick, vehicle, after self-admin0.90.92.6-0.90.81.41.2-1.01.41.20.7-1.6-0.5-0.4-0.70.7-1.1-0.60.1-1.20.4
Time to tail flick, test, before self-admin0.60.61.60.7-0.4-0.4-0.2-0.9-0.50.60.20.01.1-0.4-1.11.1-0.60.7-1.2-0.31.2
Time to tail flick, test, after self-admin2.22.35.2-0.60.11.00.8-2.20.71.50.8-1.71.2-1.0-2.32.2-2.10.0-1.5-1.92.2
Delta time to tail flick, vehicle, before/after SA0.30.21.3-0.30.30.80.20.10.50.10.5-1.1-0.6-0.40.4-0.4-0.5-0.10.4-0.7-0.4
Delta time to tail flick, test, before/after SA0.40.31.4-0.3-0.10.40.1-0.40.30.20.6-1.10.3-0.6-0.50.5-1.00.1-0.4-1.20.6
Tibia length0.30.82.9-0.40.70.10.40.80.3-0.9-1.11.1-0.81.30.5-0.41.3-0.90.71.7-1.0
Ambulatory time before self-admin1.11.23.70.60.4-0.5-1.00.8-1.2-0.6-1.81.9-0.31.4-0.40.51.61.10.61.7-0.3
Ambulatory time after self-admin2.02.26.92.2-1.5-2.0-2.41.0-2.6-0.7-0.41.81.5-0.3-0.20.20.72.4-1.10.90.9
Bone: tissue strength0.10.10.40.4-0.2-0.2-0.3-0.1-0.40.1-0.00.20.5-0.1-0.50.5-0.00.6-0.40.40.5
Total heroin consumption0.70.82.6-0.80.91.10.80.41.10.00.2-1.1-1.60.20.9-0.9-0.0-0.81.3-0.4-1.3
Bone: trabecular number0.40.61.20.9-0.8-1.1-1.01.1-1.0-0.8-0.40.90.20.10.6-0.60.70.6-0.20.9-0.3
Bone: trabecular spacing1.21.66.2-0.90.31.31.0-1.41.31.21.5-2.20.2-1.2-0.60.6-1.9-0.6-0.7-2.50.8
Bone: trabecular thickness3.03.59.00.8-0.5-1.7-1.33.0-1.3-2.5-1.52.3-1.11.52.6-2.62.60.21.51.4-2.4
Bone: trabecular tissue density0.10.10.60.00.2-0.2-0.20.1-0.3-0.7-0.40.8-0.20.6-0.10.10.5-0.00.20.1-0.1
Water consumed over 24 hours1.61.97.20.20.00.50.1-1.9-0.31.7-0.10.11.6-0.5-2.72.7-1.01.2-1.5-0.32.4
Number of responses in last shaping day0.50.51.61.3-0.8-0.8-1.10.8-1.1-0.70.50.40.2-0.50.7-0.70.31.2-0.20.3-0.2