Hub : Genes

Tex9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Tex9 0.37 0.2 1.4e-03 0.16 0.15 0.11 0.17 4.2e-05 1.0e-04 9.1e-04 2.8e-05
2 pVTA gene expression Tex9 0.31 0.11 0.0e+00 0.24 0.25 0.24 0.24 2.8e-19 2.0e-20 2.8e-19 1.3e-19
3 Brain gene expression Tex9 0.41 0.12 0.0e+00 0.3 0.29 0.3 0.3 1.1e-28 1.7e-27 3.7e-28 6.9e-29
4 Brain alternative TSS XM_006243344.5 0.03 0.02 3.8e-03 0.04 0.03 0.02 0.03 1.4e-04 1.2e-03 5.3e-03 6.2e-04
5 BLA gene expression Tex9 0.14 0.08 1.2e-05 0.09 0.09 0.07 0.08 1.3e-05 2.6e-05 9.2e-05 4.6e-05
6 NAcc gene expression Tex9 0.15 0.07 2.2e-15 0.11 0.1 0.11 0.11 3.8e-16 6.9e-15 1.1e-15 1.0e-15
7 Liver gene expression Tex9 0.3 0.12 0.0e+00 0.24 0.23 0.23 0.23 9.6e-27 4.1e-25 1.2e-25 1.1e-25
8 IC gene expression Tex9 0.16 0.09 2.2e-05 0.1 0.12 0.12 0.12 5.2e-05 8.0e-06 1.3e-05 1.4e-05
9 Adipose gene expression Tex9 0.56 0.08 0.0e+00 0.31 0.43 0.43 0.43 7.8e-35 2.3e-52 2.7e-51 1.4e-51
10 PL alternative polyA XM_039082508.2 0.04 0.03 3.5e-03 0.02 0.02 0.02 0.02 1.2e-03 2.2e-03 5.5e-03 3.7e-03
11 PL gene expression Tex9 0.09 0.05 3.8e-09 0.09 0.07 0.07 0.07 1.3e-09 2.1e-08 5.8e-08 1.8e-08
12 Liver alternative TSS XM_006243344.5 0.09 0.05 8.1e-08 0.02 0.04 0.02 0.03 2.6e-03 4.8e-05 1.4e-03 4.5e-04
13 Liver alternative polyA NM_001399268.1 0.05 0.04 6.9e-04 0.01 0.02 0.01 0.01 1.1e-02 3.0e-03 1.8e-02 1.1e-02
14 Liver alternative polyA NM_001399268.1 0.03 0.02 4.9e-03 0 0.01 -0 0 1.0e-01 3.6e-02 4.2e-01 1.2e-01
15 PL alternative polyA XM_006243344.5 0.04 0.03 8.2e-04 0.02 0.02 0.02 0.03 5.7e-03 2.3e-03 1.1e-03 5.8e-04
16 Liver alternative polyA XM_006243344.5 0.04 0.03 2.4e-03 0.01 0.01 0.01 0.01 7.7e-03 1.1e-02 2.1e-02 2.3e-02
17 NAcc alternative polyA XM_039082508.2 0.02 0.01 1.2e-03 0.01 0.01 0.01 0.01 1.8e-03 1.7e-03 6.1e-03 2.4e-03
18 PL alternative TSS XM_006243344.5 0.04 0.03 9.0e-04 0.02 0.03 0.02 0.02 1.0e-03 7.4e-04 4.5e-03 3.1e-03
19 Adipose isoform ratio XM_039082508.2 0.1 0.05 1.1e-11 0.06 0.08 0.08 0.08 4.0e-07 1.8e-09 9.2e-09 7.9e-09
20 Adipose alternative polyA XM_039082508.2 0.1 0.06 3.7e-12 0.05 0.08 0.06 0.07 5.6e-06 3.3e-09 1.4e-07 1.9e-08
21 Adipose alternative TSS XM_063265174.1 0.05 0.04 1.0e-03 0.01 0.01 0.01 0.01 4.4e-02 6.9e-03 6.0e-02 3.9e-02
22 IC alternative polyA XM_006243344.5 0.1 0.11 6.5e-03 0.02 0.03 0.03 0.03 3.3e-02 1.5e-02 2.6e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.20.40.7-0.5-0.7-0.50.50.60.40.5-0.7-0.5-0.80.3-0.8-0.8-0.7-0.7-0.60.7-0.70.30.30.5-0.7
Area under the delay curve0.30.51.60.20.00.10.20.2-0.0-0.1-0.2-0.50.00.1-0.4-0.6-0.6-0.8-0.71.0-1.11.31.31.1-1.1
BMI with tail4.114.427.04.65.15.1-4.9-4.9-5.0-5.05.03.45.2-4.64.23.43.51.80.8-1.50.62.62.00.3-0.8
BMI without tail0.73.99.51.82.62.4-2.3-2.5-2.3-2.32.81.63.1-2.42.52.22.31.30.8-1.40.90.70.3-0.60.4
Body weight2.410.620.94.14.34.3-4.3-4.4-4.3-4.34.22.24.6-4.23.12.22.50.5-0.6-0.5-0.53.22.61.2-1.7
Weight adjusted by age2.05.710.12.32.82.6-3.2-3.2-2.8-2.33.02.52.8-3.22.92.72.72.01.5-2.11.7-0.1-0.5-1.31.1
Bone surface0.10.10.40.40.30.5-0.4-0.5-0.4-0.40.40.40.3-0.70.30.30.30.30.2-0.30.1-0.0-0.1-0.2-0.0
Bone volume0.10.10.50.50.40.5-0.4-0.5-0.5-0.50.30.30.0-0.70.10.00.1-0.1-0.20.1-0.20.40.30.2-0.4
Breakpoint value in progressive ratio session0.00.00.3-0.20.10.10.1-0.20.4-0.10.3-0.30.5-0.50.20.10.10.10.0-0.0-0.10.20.10.0-0.0
Number of licking bursts0.61.83.8-1.9-1.8-1.91.81.61.82.0-1.5-1.0-1.51.5-1.0-0.6-0.70.10.10.00.3-1.5-1.3-0.81.1
Context. condit. distance diff. score0.50.61.4-0.1-0.3-0.20.30.50.10.1-0.7-0.4-0.80.5-0.9-1.0-1.0-0.9-1.11.1-1.00.91.01.1-1.2
Locomotion velocity, session 12.42.74.51.01.51.3-1.2-1.5-1.2-1.11.71.71.4-1.12.02.12.02.02.1-2.02.0-1.2-1.4-1.81.8
Locomotion distance, session 10.30.40.9-0.7-0.4-0.50.70.50.70.6-0.40.1-0.50.20.00.20.10.40.9-0.40.7-1.0-0.9-0.71.0
Locomotion velocity, session 20.10.10.4-0.40.2-0.1-0.1-0.30.10.20.5-0.50.5-0.30.40.40.50.10.3-0.60.5-0.4-0.4-0.30.6
Locomotion distance, session 20.20.30.8-0.50.1-0.10.0-0.20.20.10.50.00.6-0.70.60.60.60.50.8-0.70.7-0.7-0.7-0.80.9
Locomotion velocity, session 31.11.34.3-0.9-0.2-0.50.60.40.60.50.10.4-0.00.30.60.90.80.91.3-1.51.8-2.1-2.0-1.72.1
Locomotion distance, session 31.71.94.5-2.1-1.9-2.01.91.81.92.0-1.7-1.2-1.51.5-1.2-0.9-1.0-0.5-0.20.3-0.0-1.2-0.9-0.40.7
Stereotopy head waving bouts, day 30.70.91.91.41.21.1-1.2-1.0-1.2-1.21.01.30.8-0.51.01.00.90.70.8-0.80.8-0.1-0.2-0.40.4
Stereotopy head waving duration, day 31.41.73.81.91.71.7-1.6-1.5-1.7-1.71.41.80.9-0.91.41.31.30.90.9-1.11.0-0.0-0.2-0.50.4
Locomotion velocity, session 70.70.71.8-1.1-0.9-1.11.01.11.01.1-1.1-0.8-1.40.8-0.9-0.8-0.9-0.6-0.40.5-0.2-0.3-0.10.30.0
Locomotion distance, session 71.01.23.0-1.7-1.4-1.51.51.51.51.5-1.3-1.0-1.51.0-0.9-0.6-0.7-0.10.10.00.3-1.2-1.0-0.50.8
Stereotopy head waving bouts, day 70.91.11.70.71.00.9-1.0-1.0-1.1-0.91.21.21.2-1.11.31.31.31.00.9-1.21.1-0.5-0.7-1.00.9
Stereotopy head waving duration, day 71.31.62.60.81.10.9-1.0-1.1-1.1-0.91.31.51.1-1.01.41.51.51.31.4-1.61.6-1.1-1.2-1.41.3
Locomotion velocity, session 80.50.61.40.00.40.4-0.4-0.6-0.1-0.30.80.40.8-0.80.70.80.90.80.9-1.21.0-0.9-1.0-1.00.9
Locomotion distance, session 80.30.51.8-1.3-1.0-1.01.00.91.01.0-0.7-0.9-0.60.3-0.7-0.6-0.5-0.3-0.10.2-0.2-0.5-0.4-0.10.2
Degree of sensitization distance0.00.00.2-0.1-0.1-0.10.10.20.10.1-0.2-0.1-0.50.0-0.1-0.1-0.10.10.2-0.10.2-0.2-0.2-0.10.1
Degree of sensitization stereotypy0.70.81.40.50.90.8-0.9-0.9-0.9-0.71.01.11.0-0.81.21.21.10.90.8-1.01.0-0.5-0.6-0.90.8
Conditioned locomotion1.21.44.50.40.40.3-0.3-0.1-0.4-0.3-0.1-0.6-0.30.1-0.5-0.9-0.9-1.7-1.81.5-1.52.12.12.0-1.8
Cocaine response after cond. corrected3.04.48.12.82.82.7-2.7-2.4-2.7-2.72.42.71.7-2.02.42.22.11.71.5-1.61.50.2-0.1-0.70.6
Cocaine response after cond. not corrected2.23.26.42.52.42.3-2.3-2.1-2.2-2.42.02.41.2-1.92.01.81.71.41.3-1.31.20.20.0-0.50.4
Cocaine response before conditioning0.91.11.9-1.2-1.2-1.11.11.01.21.2-1.1-1.4-1.00.4-1.1-1.1-1.1-1.2-1.01.2-1.10.50.60.8-0.7
Saline control response0.50.72.00.40.40.3-0.3-0.4-0.3-0.30.31.1-0.1-0.70.70.90.80.91.2-1.21.4-1.3-1.3-1.21.3
Bone: connectivity density0.91.43.2-1.8-1.8-1.61.71.61.51.6-1.3-1.0-1.11.1-1.2-0.8-0.8-0.40.10.10.0-1.3-1.1-0.60.6
Bone: cortical apparent density0.40.71.7-1.0-0.9-1.11.11.21.11.1-1.1-0.6-1.21.3-0.7-0.6-0.7-0.20.10.30.0-0.5-0.4-0.00.3
Bone: cortical area0.71.13.92.01.61.4-1.4-1.0-1.6-1.50.61.3-0.3-0.60.50.30.1-0.5-0.60.20.11.11.11.0-0.7
Bone: cortical porosity0.90.91.6-0.6-0.8-0.90.90.70.90.8-1.0-1.2-1.00.4-1.2-1.3-1.3-1.2-1.11.1-1.00.60.81.1-0.9
Bone: cortical porosity1.92.13.5-1.0-1.2-1.11.11.01.11.1-1.3-1.9-1.00.8-1.7-1.8-1.8-1.8-1.81.7-1.71.11.31.7-1.6
Bone: cortical thickness0.40.62.40.50.0-0.20.20.60.00.0-0.90.2-1.51.0-0.8-0.8-1.1-1.0-1.00.9-0.40.70.91.2-0.8
Bone: cortical thickness0.20.20.80.50.10.00.10.3-0.0-0.1-0.40.1-0.90.4-0.4-0.5-0.6-0.5-0.70.4-0.10.30.40.7-0.4
Bone: cortical tissue density0.50.71.7-1.1-1.0-1.21.11.21.11.2-1.1-0.7-1.21.3-0.7-0.6-0.7-0.20.10.30.0-0.6-0.4-0.10.4
Condit. Reinf. active minus inactive responses1.82.15.6-1.8-1.5-1.31.31.21.41.4-1.0-2.4-0.11.0-1.4-1.5-1.3-1.4-1.71.7-2.01.11.21.2-1.3
Condit. Reinf. active-inactive response ratio1.71.83.8-0.4-0.8-0.60.70.80.70.6-1.1-1.4-0.80.9-1.4-1.6-1.5-1.6-1.91.9-2.01.71.81.8-1.8
Condit. Reinf. active responses0.70.94.0-2.0-1.3-1.21.21.01.31.3-0.5-1.80.50.8-0.7-0.7-0.5-0.3-0.60.6-1.00.10.10.1-0.2
Condit. Reinf. inactive responses1.11.44.0-1.6-0.6-0.70.70.30.80.80.4-0.30.80.20.50.81.01.61.5-1.51.2-2.0-2.0-1.91.8
Incentive salience index mean1.62.15.7-1.6-1.2-1.11.10.91.21.2-0.8-2.40.00.8-1.3-1.5-1.3-1.5-1.91.8-2.11.51.61.5-1.6
Condit. Reinf. lever presses1.01.54.0-1.4-0.8-0.90.80.61.00.9-0.6-2.0-0.10.5-1.1-1.3-1.1-1.2-1.71.5-1.71.31.41.4-1.4
Condit. Reinf. active minus inactive responses1.01.54.71.31.31.5-1.6-1.8-1.4-1.51.80.81.7-2.21.21.01.31.10.2-0.70.10.50.3-0.3-0.3
Condit. Reinf. active-inactive response ratio0.91.53.41.81.61.7-1.8-1.8-1.6-1.71.51.20.9-1.71.00.80.90.70.1-0.40.10.90.70.2-0.6
Condit. Reinf. active responses0.60.84.10.70.71.1-1.1-1.4-0.9-0.91.20.01.3-2.00.60.30.60.4-0.50.1-0.71.00.80.3-0.8
Condit. Reinf. inactive responses0.50.82.3-1.5-1.3-0.91.00.71.01.2-0.7-1.50.0-0.0-0.9-0.9-0.7-0.7-1.00.8-1.10.30.30.3-0.6
Condit. Reinf. lever presses0.30.51.50.0-0.3-0.20.10.30.20.2-0.6-0.5-1.10.2-0.8-0.8-0.8-0.7-1.20.9-0.80.80.81.0-0.9
Condit. Reinf. lever reinforcers received0.50.73.00.60.60.9-1.0-1.2-0.8-0.81.0-0.11.0-1.70.30.10.30.2-0.80.3-0.81.21.00.6-1.0
Conditioned reinforcement - actives0.00.10.30.50.30.10.1-0.0-0.2-0.40.20.5-0.20.00.20.20.20.20.3-0.30.4-0.1-0.2-0.20.2
Conditioned reinforcement - inactives0.10.31.20.90.50.40.10.4-0.4-0.70.21.1-0.40.20.40.50.30.60.9-0.50.7-0.4-0.4-0.40.4
Conditioned locomotion0.71.12.3-0.1-0.4-0.50.80.70.50.2-0.7-0.8-0.90.6-1.1-1.2-1.2-1.3-1.51.4-1.41.31.31.4-1.5
Patch foraging indifference point 0 sec0.20.51.20.20.60.3-0.5-0.5-0.5-0.20.70.60.6-0.60.91.00.90.70.7-1.01.1-0.7-0.8-0.81.1
Patch foraging indifference point AUC0.71.75.0-2.2-1.9-1.71.81.41.91.7-1.1-2.10.00.6-1.2-1.1-0.9-0.9-0.60.9-1.2-0.10.00.1-0.3
Delay disc. indifference point, 0s delay1.31.53.1-1.6-1.6-1.41.71.61.51.4-1.3-1.8-0.70.8-1.3-1.3-1.2-0.9-0.81.2-1.20.30.40.6-0.6
Delay disc. indifference point, 16s delay0.91.33.40.2-0.2-0.00.20.30.00.0-0.6-0.8-0.50.5-0.9-1.2-1.2-1.6-1.41.6-1.61.81.81.8-1.8
Delay disc. indifference point, 2s delay0.10.10.30.1-0.3-0.20.40.40.20.1-0.50.1-0.50.4-0.3-0.3-0.30.10.30.2-0.1-0.1-0.10.0-0.1
Delay disc. indifference point, 24s delay0.20.30.8-0.2-0.3-0.30.40.40.30.2-0.5-0.5-0.40.4-0.6-0.7-0.7-0.9-0.60.7-0.70.60.60.7-0.7
Delay disc. indifference point, 4s delay1.21.32.6-0.4-0.8-0.61.00.90.70.5-0.9-1.2-0.50.9-1.2-1.3-1.3-1.3-1.41.5-1.61.31.41.5-1.5
Delay disc. indifference point, 8s delay0.10.20.80.30.40.5-0.2-0.0-0.3-0.40.3-0.00.6-0.40.20.10.1-0.1-0.10.4-0.60.90.80.5-0.6
Indifference point function ln k0.92.77.02.62.32.1-2.2-2.0-2.2-2.21.72.30.9-1.41.81.61.51.21.0-1.21.30.20.0-0.40.4
Indifference point function log k0.92.77.02.62.32.1-2.2-2.0-2.2-2.21.72.30.9-1.41.81.61.51.21.0-1.21.30.20.0-0.40.4
Patch foraging total patch changes 0 sec0.30.71.50.40.90.5-0.7-0.7-0.6-0.40.90.80.8-0.81.11.11.00.80.8-1.11.2-0.7-0.8-0.91.2
Patch foraging total patch changes 12 sec0.30.41.4-1.2-0.9-1.01.00.90.91.0-0.7-0.7-0.20.2-0.5-0.4-0.4-0.30.00.1-0.0-0.6-0.5-0.40.4
Patch foraging total patch changes 18 sec0.00.10.3-0.4-0.2-0.30.30.30.30.4-0.0-0.20.3-0.10.20.20.2-0.00.2-0.20.3-0.3-0.3-0.40.5
Patch foraging total patch changes 24 sec0.20.82.4-1.0-0.5-0.60.60.30.70.70.1-0.00.3-0.00.50.70.70.91.0-1.01.0-1.5-1.5-1.51.6
Patch foraging total patch changes 6 sec0.20.41.8-1.4-0.7-0.70.60.40.80.9-0.1-0.70.5-0.10.10.20.30.30.4-0.40.2-0.8-0.8-0.90.8
Patch foraging time to switch 0 sec0.41.53.2-0.8-1.0-0.81.11.20.91.0-1.4-1.1-1.81.4-1.6-1.6-1.6-1.5-1.51.2-1.00.50.71.3-1.1
Patch foraging water rate 0 sec0.83.04.91.82.01.7-2.0-2.0-1.9-1.82.11.82.2-1.92.22.12.01.71.6-1.51.4-0.2-0.5-1.11.0
Patch foraging water rate 12 sec1.87.310.92.62.72.5-2.8-2.9-2.8-2.72.93.32.7-2.53.23.23.23.33.1-2.82.5-1.2-1.5-2.32.0
Patch foraging water rate 18 sec0.51.12.01.11.01.0-1.2-1.3-1.3-1.11.01.40.7-1.21.21.21.10.91.0-1.00.9-0.4-0.5-0.80.7
Patch foraging water rate 24 sec0.50.82.6-0.1-0.2-0.30.1-0.10.1-0.00.20.70.3-0.30.50.80.81.31.6-1.01.0-1.4-1.4-1.51.3
Patch foraging water rate 6 sec1.11.63.01.01.00.9-1.1-1.2-1.0-0.91.31.41.5-1.31.51.61.61.71.7-1.31.1-0.7-0.9-1.31.1
Seeking ratio, delayed vs. immediate footshock0.40.61.60.90.91.1-1.1-1.3-1.0-1.01.00.80.8-0.90.80.70.80.50.3-0.40.10.40.2-0.2-0.1
Distance traveled before self-admin0.00.10.3-0.00.20.0-0.0-0.4-0.10.10.10.00.0-0.50.20.20.20.30.1-0.30.3-0.2-0.2-0.20.3
Distance traveled after self-admin1.62.85.02.02.21.9-1.7-1.6-1.7-1.71.92.01.3-1.72.12.01.91.71.3-1.81.8-0.5-0.6-1.01.1
Extensor digitorum longus weight4.518.034.35.25.35.6-5.5-5.6-5.4-5.65.73.85.9-5.24.63.94.22.81.4-2.41.21.91.1-0.6-0.4
Bone: elastic displacement0.10.10.40.1-0.00.2-0.2-0.2-0.0-0.20.2-0.10.6-0.4-0.0-0.1-0.1-0.1-0.30.4-0.60.60.50.3-0.6
Bone: elastic work0.60.72.30.2-0.2-0.0-0.00.1-0.1-0.0-0.3-0.60.1-0.1-0.7-0.9-0.8-0.8-1.41.2-1.41.41.41.3-1.5
Bone: endosteal estimation1.33.36.52.22.42.4-2.4-2.6-2.5-2.32.31.61.9-2.42.11.81.81.00.7-1.20.90.60.3-0.40.2
Bone: endosteal perimeter1.84.39.22.82.72.9-2.9-3.0-3.0-2.82.61.62.4-2.91.91.51.60.6-0.1-0.60.11.61.20.4-0.8
Epididymis fat weight0.00.20.9-0.9-0.5-0.60.60.40.30.5-0.1-0.40.00.4-0.1-0.00.10.20.2-0.40.3-0.8-0.7-0.50.5
Delta time in closed arm before/after self-admin0.30.30.7-0.3-0.3-0.50.50.80.40.2-0.5-0.4-0.50.8-0.6-0.6-0.7-0.8-0.60.7-0.60.50.50.7-0.5
Delta time in open arm before/after self-admin0.50.52.1-0.5-0.5-0.40.60.60.30.7-0.40.4-0.60.6-0.10.20.20.70.7-0.80.9-1.5-1.4-1.11.0
Diff in mean of infusions in LGA sessions0.51.03.60.20.30.7-0.2-0.5-0.1-0.70.3-0.50.7-0.8-0.3-0.6-0.5-0.5-1.01.2-1.61.91.81.4-1.8
Delay discount exponential model param0.20.31.2-0.3-0.1-0.2-0.1-0.10.10.20.10.3-0.10.00.30.40.50.60.6-0.80.9-1.1-1.1-0.90.9
Extinction: sum of active levers before priming0.40.61.80.00.3-0.1-0.3-0.3-0.10.10.50.30.6-0.40.70.90.80.90.9-1.21.2-1.1-1.1-1.11.3
Active lever presses in extinction session 60.40.40.80.70.60.8-0.5-0.6-0.4-0.80.70.60.9-0.80.60.60.70.80.8-0.50.3-0.0-0.1-0.40.2
Bone: final force0.50.92.21.51.31.3-1.3-1.2-1.3-1.30.80.60.4-1.10.50.20.2-0.2-0.70.2-0.21.11.00.9-0.9
Bone: final moment0.50.92.11.51.11.2-1.1-1.0-1.2-1.20.50.5-0.0-0.80.2-0.1-0.1-0.5-1.00.5-0.41.31.31.2-1.1
Food consumed during 24 hour testing period1.12.23.31.81.71.6-1.6-1.6-1.6-1.51.51.81.1-1.41.81.81.71.41.5-1.51.6-0.6-0.8-1.21.2
Glucose0.81.23.00.40.70.6-0.6-0.7-0.5-0.60.91.31.0-0.51.31.41.41.61.7-1.31.3-1.0-1.1-1.41.4
Heart weight0.30.41.6-0.00.30.6-0.6-0.8-0.6-0.40.8-0.41.3-1.00.30.10.4-0.2-0.60.3-0.91.00.80.3-0.8
Delay discount hyperbolic model param0.40.51.4-0.20.1-0.0-0.3-0.3-0.00.10.30.50.1-0.20.50.60.70.80.7-1.01.1-1.2-1.2-1.11.1
Intermittent access intake day 1-15 change0.10.72.70.80.40.30.20.2-0.2-0.80.21.2-0.40.20.60.80.61.11.6-0.91.1-1.0-1.0-1.00.9
Intermittent access intake escalation0.10.62.01.00.60.6-0.0-0.1-0.4-1.00.31.3-0.30.10.60.70.61.01.4-0.80.9-0.6-0.7-0.70.6
Intermittent access intake escalation 20.40.62.11.51.11.0-0.7-0.7-0.9-1.40.81.20.3-0.30.90.80.70.70.7-0.50.60.20.1-0.20.2
Intermitt. access day 1 inactive lever presses0.00.62.70.1-0.4-0.60.91.40.40.2-0.90.1-1.31.6-0.7-0.7-0.8-0.6-0.20.7-0.40.30.40.6-0.5
Intermitt. access day 15 inactive lever presses0.10.41.51.20.80.8-0.5-0.5-0.6-1.10.70.90.4-0.30.60.50.50.40.6-0.20.10.40.30.0-0.3
Intermitt. access escalation Index0.10.51.20.30.40.3-1.0-1.1-0.7-0.30.6-0.61.1-1.00.3-0.00.1-0.6-0.80.4-0.71.00.90.7-0.6
Intermittent access day 1 total infusions0.30.82.7-0.6-0.8-1.01.21.31.00.9-1.2-0.3-1.61.6-0.9-0.7-0.8-0.5-0.20.20.2-0.6-0.50.10.2
Intermittent access day 15 total infusions0.20.52.5-0.1-0.6-0.71.21.00.70.3-1.00.0-1.61.4-0.8-0.6-0.7-0.20.20.20.1-0.5-0.40.00.1
Intermittent access terminal intake (last 3 days)0.30.52.20.2-0.3-0.40.80.80.40.1-0.90.1-1.51.4-0.8-0.7-0.8-0.6-0.40.6-0.30.20.30.6-0.5
Intermittent access total infusions0.30.31.40.0-0.2-0.50.80.70.30.3-0.60.4-1.21.2-0.3-0.1-0.2-0.00.2-0.30.7-0.8-0.7-0.40.6
Intermittent access day 1 locomotion0.81.44.1-0.9-1.4-1.41.61.51.31.3-1.7-0.7-2.02.0-1.4-1.2-1.3-0.7-0.40.6-0.2-0.6-0.40.2-0.0
Intermittent access day 15 total locomotion0.10.41.90.5-0.3-0.50.80.80.30.1-0.80.0-1.41.2-0.7-0.7-0.8-0.6-0.60.6-0.20.20.30.6-0.5
Intermittent access total locomotion0.10.10.30.50.20.10.1-0.0-0.1-0.2-0.00.6-0.40.30.10.20.10.30.2-0.30.4-0.3-0.3-0.20.2
Intermittent access standard deviation0.10.41.11.00.70.40.20.1-0.3-0.80.31.0-0.30.50.60.60.40.50.8-0.71.0-0.5-0.5-0.40.6
Left kidney weight1.07.712.93.43.53.6-3.5-3.4-3.6-3.43.43.33.0-2.83.22.92.92.41.8-2.01.60.4-0.0-1.00.6
Right kidney weight1.07.010.92.42.93.0-3.0-3.1-3.0-2.73.22.93.3-2.93.23.13.22.82.2-2.41.9-0.4-0.8-1.81.3
Cocaine induced anxiety0.30.82.0-0.3-0.4-0.50.60.50.60.5-0.6-1.1-0.40.6-0.7-0.9-0.9-1.4-1.41.2-1.11.11.21.2-1.0
Post-drug Anxiety1.71.94.3-1.8-1.9-1.82.01.62.11.8-1.7-1.6-1.51.7-1.4-1.1-1.2-0.9-0.40.7-0.4-0.7-0.5-0.00.3
Baseline Anxiety1.22.07.1-1.6-1.4-1.21.20.81.31.3-0.8-0.1-0.70.8-0.20.40.41.11.7-1.31.5-2.7-2.6-2.22.2
Tail length0.21.22.8-1.6-1.4-1.41.31.11.51.5-0.7-1.0-0.41.1-0.5-0.2-0.10.10.3-0.60.6-1.7-1.6-1.11.2
Length with tail0.10.31.10.60.50.6-0.7-0.9-0.6-0.50.90.21.0-0.90.60.50.70.30.0-0.60.3-0.1-0.2-0.30.2
Length without tail1.15.911.63.43.13.2-3.4-3.4-3.3-3.23.01.73.0-3.42.11.51.60.4-0.5-0.2-0.52.42.01.0-1.5
Times rat made contact with spout0.10.10.50.30.20.1-0.10.0-0.2-0.1-0.20.7-0.60.30.30.40.10.30.4-0.20.4-0.2-0.2-0.30.4
Lifetime Intake0.20.31.20.0-0.2-0.50.80.70.30.3-0.50.4-1.11.0-0.2-0.0-0.20.00.2-0.30.7-0.8-0.7-0.40.6
Liver weight, left2.54.37.81.92.32.3-2.2-2.4-2.2-2.22.62.22.8-2.12.72.52.52.31.8-1.81.3-0.1-0.4-1.41.0
Liver weight, right1.01.82.71.41.61.6-1.3-1.5-1.5-1.51.61.61.5-1.41.61.51.61.51.1-1.21.0-0.1-0.4-0.90.5
Locomotor activity3.45.310.43.13.13.0-3.2-3.2-3.1-3.02.92.32.7-2.82.52.02.11.10.5-1.20.81.10.8-0.0-0.2
Locomotor testing distance1.94.88.42.92.92.8-2.9-2.8-2.9-2.72.72.72.3-2.22.52.22.21.71.2-1.51.20.50.2-0.60.3
Locomotor testing rearing0.31.32.81.21.11.3-1.3-1.3-1.3-1.31.41.21.7-1.11.31.21.31.31.0-0.90.50.0-0.2-0.70.3
Locomotion in novel chamber0.20.20.70.30.10.00.50.80.10.1-0.40.2-0.80.6-0.3-0.3-0.5-0.5-0.40.5-0.30.50.50.6-0.5
Locomotion in novel chamber post-restriction0.30.81.4-0.8-0.9-0.80.70.80.80.6-0.8-1.2-0.50.6-1.1-1.1-1.0-0.8-1.01.1-1.20.70.80.9-1.0
Fecal boli incidents, locomotor time 10.30.82.0-0.8-0.8-0.70.40.30.80.7-0.8-1.4-0.40.5-0.9-1.0-1.0-1.4-1.21.0-1.00.60.70.9-0.7
Change in fecal boli incidents, locomotor task2.02.14.82.11.81.5-1.0-0.9-1.6-1.51.42.20.6-0.61.81.81.61.51.6-1.51.7-0.6-0.8-1.01.2
Time >=10cm from walls, locomotor time 10.30.31.20.60.60.6-0.5-0.4-0.5-0.70.30.40.0-0.00.1-0.0-0.10.0-0.20.5-0.61.11.00.8-0.9
Bouts of movement, locomotor time 10.10.10.3-0.10.30.2-0.2-0.30.00.00.4-0.30.6-0.50.40.30.30.1-0.3-0.10.00.30.30.10.1
Total resting periods, locomotor time 10.10.10.3-0.10.30.1-0.2-0.30.00.10.4-0.20.4-0.50.40.30.30.1-0.2-0.20.20.10.1-0.00.3
Rest time, locomotor task time 10.30.51.8-0.00.3-0.10.1-0.10.10.3-0.1-0.8-0.20.3-0.2-0.4-0.5-1.2-1.30.8-0.71.11.21.2-0.6
Distance moved, locomotor task time 10.10.40.9-0.8-0.8-0.60.50.90.50.5-0.5-0.0-0.30.6-0.4-0.1-0.10.70.7-0.30.3-1.0-0.9-0.70.5
Vertical activity count, locomotor time 10.00.20.6-0.6-0.8-0.60.30.80.40.4-0.5-0.5-0.30.5-0.7-0.6-0.50.10.00.4-0.5-0.0-0.00.1-0.3
Time >=10cm from walls, locomotor time 20.00.10.40.20.30.1-0.1-0.4-0.4-0.20.10.10.0-0.10.20.1-0.0-0.1-0.10.3-0.30.60.60.5-0.3
Bouts of movement, locomotor time 20.20.61.10.10.60.6-0.7-0.9-0.5-0.40.90.51.0-1.01.01.01.00.70.7-0.80.7-0.4-0.6-0.90.8
Total resting periods, locomotor time 20.20.81.50.20.70.6-0.8-0.9-0.6-0.41.00.71.0-1.11.21.21.20.90.9-1.10.9-0.6-0.7-1.11.0
Rest time, locomotor task time 20.10.10.4-0.1-0.0-0.30.50.20.60.5-0.3-0.5-0.40.5-0.2-0.2-0.4-0.6-0.60.3-0.00.20.30.40.0
Distance moved, locomotor task time 20.30.41.4-0.8-0.5-0.40.10.20.10.3-0.10.10.1-0.0-0.00.20.41.10.9-0.70.6-1.2-1.2-1.00.8
Vertical activity count, locomotor time 20.20.51.3-1.0-1.1-1.00.40.80.60.8-0.8-0.4-1.00.5-0.7-0.4-0.40.30.6-0.20.3-1.1-1.0-0.60.7
Light reinforcement 10.52.38.21.41.91.8-1.9-2.1-1.8-1.82.10.62.9-1.91.61.11.30.5-0.3-0.1-0.41.71.40.5-0.7
Light reinforcement 20.10.20.80.40.20.10.10.20.1-0.0-0.30.0-0.50.5-0.1-0.2-0.4-0.9-0.60.4-0.10.50.50.7-0.2
Bone: marrow area1.43.46.82.32.42.5-2.5-2.6-2.5-2.42.31.71.9-2.42.11.81.80.90.7-1.20.90.60.3-0.30.2
Bone: maximum diameter2.34.610.63.23.13.0-3.0-2.9-3.1-3.02.52.31.9-2.42.21.91.70.70.5-1.01.01.10.80.2-0.2
Bone: maximum force0.50.91.91.41.21.3-1.3-1.3-1.4-1.20.90.50.5-1.10.40.10.2-0.3-0.90.2-0.41.21.10.9-1.0
Bone: maximum moment0.50.91.91.41.21.2-1.2-1.1-1.3-1.20.60.40.1-0.80.2-0.1-0.1-0.6-1.10.5-0.51.41.31.2-1.2
Mean time between licks in bursts0.10.40.9-0.6-0.9-0.80.80.80.80.8-0.8-0.7-0.40.5-0.8-0.7-0.7-0.4-0.50.6-0.6-0.00.00.2-0.3
Mean num. licks in bursts0.82.05.32.32.12.0-2.0-1.7-2.0-2.11.51.71.1-1.41.31.00.90.30.4-0.30.31.21.00.5-0.6
Cd content in liver1.61.73.3-1.6-1.7-1.51.51.11.61.5-1.4-1.8-1.00.6-1.6-1.6-1.5-1.1-1.01.4-1.50.50.60.9-1.0
Co content in liver2.42.85.8-1.1-1.1-1.21.11.31.21.2-1.3-2.0-0.91.2-1.6-1.9-1.8-2.2-2.42.1-2.21.71.92.0-1.8
Cu content in liver0.30.31.10.10.10.1-0.2-0.1-0.2-0.1-0.1-0.20.0-0.0-0.4-0.5-0.5-0.5-0.80.8-0.91.01.00.9-1.0
Fe content in liver0.60.71.60.40.60.5-0.5-0.6-0.4-0.50.60.90.4-0.80.91.11.00.81.3-1.21.3-1.0-1.0-1.11.2
K content in liver0.60.51.80.60.80.9-1.0-1.1-1.0-0.81.10.61.3-1.00.70.60.70.60.1-0.50.10.20.1-0.2-0.2
Mg content in liver0.50.62.30.60.70.9-1.0-1.2-0.8-0.71.00.41.4-1.50.70.50.70.50.1-0.3-0.10.40.3-0.1-0.2
Mn content in liver0.70.82.51.61.21.1-1.1-0.8-1.1-1.20.60.70.1-0.10.30.0-0.1-0.6-1.00.4-0.41.31.31.2-1.0
Na content in liver2.93.27.31.52.12.0-2.2-2.4-1.9-1.82.51.32.7-2.52.22.02.11.20.9-1.61.20.0-0.3-0.90.8
Rb content in liver1.01.22.00.91.11.1-0.9-1.1-0.8-1.01.21.21.1-1.41.21.21.21.21.3-1.31.2-0.6-0.8-0.90.8
Se content in liver0.30.41.4-0.00.0-0.1-0.1-0.0-0.00.10.10.6-0.3-0.20.30.50.40.60.9-0.91.1-1.2-1.1-0.91.1
Sr content in liver0.80.72.2-1.1-1.1-1.10.90.81.01.1-0.6-1.5-0.30.6-0.8-0.8-0.6-1.0-1.00.5-0.6-0.1-0.00.2-0.1
Zn content in liver0.60.72.3-0.2-0.3-0.0-0.0-0.30.00.1-0.2-0.50.2-0.6-0.6-0.8-0.7-0.8-1.01.2-1.51.41.31.1-1.5
Bone: minimum diameter0.81.54.41.20.90.9-0.8-0.6-1.1-0.80.1-0.1-0.4-0.4-0.3-0.7-0.8-1.7-1.81.3-1.22.12.12.0-1.8
Time in familiar zone, hab. session 10.40.41.30.10.10.0-0.00.00.0-0.1-0.0-0.50.20.3-0.2-0.5-0.5-0.9-1.10.8-0.91.11.11.0-0.9
Time in novel zone, hab. session 10.20.20.7-0.1-0.2-0.20.20.30.00.2-0.30.4-0.70.4-0.10.10.10.50.8-0.50.6-0.9-0.8-0.60.6
Total zone transitions, hab. session 10.50.72.0-1.1-0.6-0.90.80.80.80.8-0.40.0-0.50.60.10.40.20.71.3-0.70.9-1.4-1.3-1.11.4
Total locomotion distance, hab. session 10.40.51.5-0.8-0.5-0.50.50.40.50.5-0.20.3-0.10.20.20.50.40.71.1-0.70.8-1.2-1.2-1.21.1
Locomotion velocity, hab. session 10.30.51.4-0.5-0.1-0.20.20.10.20.20.10.50.1-0.10.50.70.70.81.2-0.80.9-1.1-1.1-1.21.1
Time in familiar zone, hab. session 20.20.20.7-0.4-0.4-0.40.40.30.40.3-0.30.1-0.20.40.00.20.10.40.3-0.40.5-0.8-0.8-0.70.7
Time in novel zone, hab. session 20.30.30.90.90.70.7-0.7-0.4-0.8-0.70.30.5-0.2-0.50.20.0-0.1-0.3-0.00.3-0.20.80.70.7-0.6
Total zone transitions, hab. session 20.10.21.0-1.0-0.7-0.50.40.20.50.5-0.1-0.70.6-0.3-0.2-0.2-0.1-0.1-0.10.3-0.60.10.1-0.1-0.2
Total locomotion distance, hab. session 20.20.20.9-0.7-0.5-0.20.1-0.10.20.30.0-0.60.9-0.8-0.2-0.2-0.1-0.1-0.30.5-0.90.50.40.1-0.5
Locomotion velocity, hab. session 20.20.20.9-0.7-0.5-0.20.20.00.20.3-0.1-0.60.7-0.6-0.3-0.4-0.3-0.3-0.50.7-1.00.60.60.3-0.6
Novel to familiar place preference ratio0.50.71.40.90.91.0-1.0-1.0-1.0-1.00.90.11.1-1.20.40.10.3-0.3-0.60.2-0.51.11.00.8-0.9
Novelty place preference0.60.81.61.11.01.1-1.2-1.1-1.2-1.11.00.21.1-1.20.50.20.3-0.4-0.60.2-0.51.31.10.9-1.0
Time in novel zone, NPP test0.81.02.01.41.31.4-1.4-1.3-1.4-1.31.20.51.2-1.30.70.40.5-0.2-0.40.0-0.31.21.00.7-0.8
Total zone transitions, NPP test0.10.10.6-0.5-0.1-0.10.0-0.20.20.10.20.00.6-0.80.40.40.40.50.6-0.20.0-0.2-0.2-0.50.4
Total locomotion distance, NPP test0.40.51.3-0.40.00.1-0.2-0.4-0.00.00.40.40.9-1.10.70.80.81.01.1-0.70.6-0.7-0.8-1.10.9
Locomotion velocity, NPP test0.30.51.3-1.0-0.4-0.40.40.00.40.50.1-0.00.6-0.70.30.50.60.91.1-0.70.5-1.0-1.0-1.21.0
Intraocular pressure0.00.10.3-0.5-0.3-0.20.10.00.20.5-0.0-0.50.0-0.4-0.2-0.1-0.00.0-0.2-0.0-0.1-0.2-0.2-0.10.1
Delta distance traveled before/after self-admin2.72.95.62.32.22.2-1.8-1.5-1.9-2.11.92.41.5-1.42.01.91.81.81.5-1.51.5-0.2-0.5-0.90.7
Delta ambulatory time before/after self-admin1.32.25.82.42.12.0-1.6-1.2-1.7-2.01.62.31.0-1.01.61.51.41.41.2-1.21.20.0-0.2-0.50.3
Parametrial fat weight0.92.04.6-1.8-2.0-2.22.01.92.12.0-1.7-1.5-1.41.4-1.3-1.0-1.1-0.8-0.50.4-0.1-1.1-0.9-0.30.7
Pavlov. Cond. lever latency0.60.83.11.40.91.0-0.8-0.5-1.0-1.00.41.8-0.5-0.00.70.80.60.61.1-0.91.2-0.7-0.7-0.60.6
Pavlov. Cond. magazine entry latency7.29.217.5-2.5-2.7-2.42.42.22.42.2-2.4-4.1-1.21.6-3.3-3.6-3.3-3.6-4.23.8-4.12.83.03.3-3.4
Pavlov. Cond. change in total contacts2.52.75.6-1.5-1.3-1.31.21.01.21.1-1.1-2.3-0.20.6-1.6-1.9-1.7-1.7-2.42.1-2.41.71.81.9-1.9
Pavlov. Cond. index score4.25.312.2-2.6-2.4-2.32.21.82.32.2-1.9-3.5-0.81.2-2.5-2.6-2.4-2.4-2.92.6-2.91.51.72.0-2.0
Pavlov. Cond. latency score3.13.99.9-2.4-2.2-2.12.01.62.12.0-1.6-3.1-0.51.1-2.1-2.2-2.0-2.0-2.42.1-2.41.21.41.6-1.6
Pavlov. Cond. lever contacts1.41.75.2-1.6-1.2-1.21.00.71.21.2-0.8-2.30.10.1-1.2-1.4-1.2-1.3-1.81.5-1.81.21.31.3-1.3
Pavlov. Cond. magazine entry number6.58.315.22.52.72.4-2.4-2.2-2.4-2.22.43.91.4-1.73.23.43.23.33.9-3.53.8-2.4-2.7-3.03.1
Pavlov. Cond. intertrial magazine entries1.41.74.8-0.5-0.0-0.10.10.10.10.20.40.90.30.30.91.31.31.72.0-1.81.8-2.1-2.2-2.22.0
Pavlov. Cond. lever-magazine prob. diff.4.04.912.0-2.5-2.3-2.22.01.72.22.1-1.8-3.5-0.61.1-2.4-2.5-2.3-2.3-2.82.6-2.91.61.82.0-2.0
Pavlov. Cond. response bias5.36.613.1-2.1-2.2-1.91.91.62.01.8-1.9-3.6-0.81.1-2.7-3.0-2.7-2.9-3.63.3-3.62.52.72.9-3.0
Pavlov. Cond. lever latency0.81.12.60.80.80.8-0.6-0.7-0.7-0.80.81.40.7-0.51.11.21.11.31.6-1.31.4-1.0-1.1-1.21.1
Pavlov. Cond. magazine entry latency1.92.64.5-1.8-2.0-2.11.92.12.02.1-2.1-1.6-2.11.9-1.8-1.6-1.7-1.5-0.91.2-0.9-0.20.10.6-0.2
Pavlov. Cond. change in total contacts0.41.01.8-1.1-1.2-1.21.01.01.01.1-1.1-1.4-0.90.7-1.2-1.1-1.1-1.1-1.20.9-0.90.20.40.7-0.5
Pavlov. Cond. index score0.91.42.2-1.3-1.4-1.41.21.21.21.4-1.3-1.5-1.21.0-1.4-1.3-1.3-1.3-1.31.2-1.10.30.50.8-0.6
Pavlov. Cond. latency score0.50.81.3-1.0-1.0-1.10.91.01.01.1-1.0-1.1-1.00.8-1.0-1.0-1.0-1.0-1.00.9-0.80.20.40.6-0.4
Pavlov. Cond. lever contacts0.60.92.1-0.8-0.8-0.80.60.70.70.8-0.8-1.3-0.70.4-1.0-1.1-1.0-1.1-1.41.2-1.20.80.91.0-0.9
Pavlov. Cond. magazine entry number1.92.44.51.81.92.0-1.8-1.9-1.9-2.02.01.52.1-1.81.71.51.61.40.9-1.10.70.40.1-0.40.1
Pavlov. Cond. intertrial magazine entries0.41.01.80.60.80.9-0.6-0.8-0.7-0.91.01.11.0-0.61.11.21.21.31.0-1.21.1-0.8-0.9-1.20.9
Pavlov. Cond. lever-magazine prob. diff.1.11.62.6-1.4-1.5-1.61.31.41.41.5-1.4-1.6-1.31.1-1.5-1.4-1.4-1.4-1.31.2-1.10.20.40.8-0.6
Pavlov. Cond. response bias2.23.04.9-1.7-1.9-1.81.61.61.61.8-1.8-2.2-1.61.3-2.0-2.0-2.0-2.0-2.11.9-1.90.91.11.5-1.4
Time in closed arm before self-admin0.30.61.1-0.4-0.5-0.50.60.60.40.2-0.7-0.7-0.80.7-0.8-0.9-0.9-0.7-0.71.0-1.00.80.90.9-1.0
Time in closed arm after self-admin0.30.31.1-0.4-0.5-0.70.71.00.50.2-0.6-0.4-0.80.8-0.6-0.6-0.7-0.5-0.40.6-0.50.30.40.5-0.5
Time in open arm before self-admin0.91.12.61.31.41.3-1.3-1.6-1.1-1.31.40.61.4-1.61.10.90.90.2-0.0-0.40.20.70.50.1-0.2
Time in open arm after self-admin0.50.51.01.01.01.0-0.7-0.8-0.9-0.70.90.90.7-0.90.80.80.80.50.3-0.60.6-0.0-0.1-0.30.3
Bone: periosteal estimation1.43.27.12.72.62.5-2.5-2.5-2.7-2.42.01.91.3-2.21.81.51.40.60.3-0.80.80.90.70.2-0.1
Bone: periosteal perimeter1.73.37.12.72.62.6-2.5-2.5-2.7-2.52.11.81.6-2.31.81.41.40.60.1-0.80.71.00.70.3-0.3
Bone: post-yield work0.00.00.1-0.00.20.3-0.2-0.3-0.3-0.20.4-0.10.2-0.20.10.10.20.0-0.2-0.1-0.10.20.10.0-0.2
Progressive ratio test 1 active lever presses0.20.30.9-0.3-0.5-0.50.80.90.50.6-0.60.2-1.00.8-0.3-0.1-0.2-0.10.4-0.30.6-0.9-0.8-0.50.6
Progressive ratio test 1 breakpoint0.20.41.0-0.3-0.5-0.60.90.90.60.6-0.60.1-1.00.8-0.3-0.1-0.2-0.10.3-0.30.5-0.9-0.8-0.50.6
Progressive ratio test 1 inactive lever presses0.82.25.7-0.8-1.3-1.51.82.21.31.2-1.60.4-2.32.4-0.8-0.3-0.50.31.3-0.61.3-2.2-2.0-1.31.5
Progressive ratio test 2 active lever presses0.30.41.51.10.90.7-0.6-0.4-0.9-0.90.61.20.1-0.20.70.70.60.60.6-0.60.7-0.1-0.2-0.30.2
Progressive ratio test 2 breakpoint0.30.41.51.10.90.7-0.6-0.4-0.9-0.90.61.20.1-0.20.70.70.60.60.6-0.60.7-0.1-0.2-0.30.3
Progressive ratio test 2 inactive lever presses0.10.21.01.00.30.10.20.5-0.3-0.4-0.20.9-0.90.8-0.1-0.0-0.2-0.10.1-0.00.3-0.1-0.00.1-0.1
Incentive Sensitization - Responses0.41.13.21.81.41.3-1.3-0.9-1.7-1.71.01.30.6-0.60.80.50.50.50.10.1-0.21.21.00.6-0.8
Incentive Sensitization - Breakpoint0.40.92.71.61.31.2-1.3-0.8-1.6-1.50.91.20.5-0.50.70.50.40.40.10.2-0.21.11.00.6-0.8
Sum of active levers in priming session hrs 5-60.30.30.80.30.50.4-0.4-0.5-0.3-0.10.40.50.3-0.50.60.70.60.60.6-0.80.9-0.6-0.6-0.60.8
Progressive ratio1.02.95.5-1.3-1.3-1.21.10.91.31.0-1.3-2.1-1.01.0-1.8-2.0-1.9-2.4-2.32.2-2.31.71.82.0-2.0
Food seeking constrained by brief footshock1.11.43.40.40.60.2-0.4-0.5-0.5-0.40.90.90.9-0.81.31.41.41.51.6-1.61.7-1.5-1.6-1.71.8
Seeking ratio, punishment vs. effort3.37.311.82.12.32.2-2.3-2.3-2.4-2.02.73.02.5-2.63.13.23.23.43.1-3.23.1-2.0-2.3-2.92.7
Retroperitoneal fat weight0.21.13.3-1.3-0.9-1.21.10.81.01.1-0.6-0.1-0.40.50.00.30.20.61.0-0.91.1-1.8-1.7-1.41.7
Reaction time number correct0.31.22.11.21.11.2-1.2-1.1-1.4-1.41.31.31.3-0.91.21.11.31.51.3-1.00.7-0.2-0.4-0.80.4
Reaction time mean minus median0.10.51.2-0.9-0.5-0.90.80.80.70.7-0.5-0.2-0.61.1-0.10.10.00.30.6-0.50.8-1.1-1.0-0.71.1
Reaction time mean minus median AUC0.21.13.2-1.2-0.8-1.21.21.21.01.0-0.8-0.2-0.91.8-0.20.1-0.10.50.8-0.71.1-1.7-1.5-1.01.5
Reaction time num false alarms0.20.41.3-0.8-0.6-0.60.50.50.50.8-0.5-0.1-0.90.2-0.3-0.0-0.00.40.5-0.50.7-1.2-1.1-0.70.9
Reaction time num false alarms AUC0.30.72.4-0.4-0.1-0.10.0-0.10.10.40.00.5-0.6-0.30.40.60.61.01.0-1.11.3-1.5-1.5-1.31.4
Reaction time trials correct on left0.31.22.11.21.11.2-1.2-1.1-1.4-1.41.31.31.3-0.91.21.11.31.51.3-1.00.7-0.2-0.4-0.80.4
Reaction time trials on left0.41.32.31.21.11.2-1.2-1.1-1.4-1.41.31.31.4-0.91.21.21.31.51.4-1.10.8-0.3-0.5-0.90.5
Reaction time mean1.02.35.2-1.7-1.8-2.02.12.12.01.8-2.0-1.2-2.12.3-1.5-1.2-1.4-1.0-0.40.7-0.1-0.8-0.60.10.4
Reaction time mean AUC0.92.14.9-1.7-1.7-2.02.02.12.01.8-1.8-1.3-1.92.2-1.4-1.1-1.3-1.0-0.40.5-0.0-0.9-0.70.00.5
Median of all reaction times2.13.36.7-1.9-2.2-2.32.42.52.32.1-2.4-1.6-2.62.5-2.0-1.8-1.9-1.6-0.91.2-0.6-0.6-0.20.5-0.1
Reaction time omissions0.30.51.4-0.5-0.1-0.30.2-0.00.30.20.20.10.40.20.40.60.61.10.8-1.00.9-1.2-1.2-1.11.1
Reaction time false alarm rate0.40.61.9-1.1-0.8-0.90.80.70.91.2-0.8-0.3-1.40.5-0.4-0.2-0.30.00.2-0.40.7-1.2-1.1-0.61.0
Reaction time premature initiation rate0.40.62.00.40.50.7-0.5-0.7-0.6-0.71.00.61.4-0.80.80.91.01.00.7-0.90.6-0.4-0.5-0.80.5
Reaction time premature initiations0.41.33.31.01.11.2-1.1-1.1-1.2-1.41.51.11.8-1.11.31.31.41.51.2-1.10.8-0.3-0.5-0.90.5
Std. dev. reaction times0.41.44.1-1.6-1.4-1.71.61.71.41.5-1.3-0.9-1.42.0-0.9-0.6-0.7-0.40.1-0.10.5-1.3-1.1-0.51.0
Reaction time trials completed0.41.32.31.21.11.2-1.2-1.1-1.4-1.41.31.31.4-0.91.21.21.31.51.4-1.10.8-0.3-0.5-0.90.5
Reaction time trials AUC0.31.02.01.00.91.1-1.1-1.0-1.2-1.31.21.21.3-0.81.11.11.21.41.3-0.90.7-0.3-0.4-0.80.4
Run reversals in cocaine runway, females0.30.40.90.20.30.5-0.4-0.2-0.3-0.00.40.40.3-0.30.60.70.70.70.6-0.80.9-0.8-0.8-0.81.0
Run reversals in cocaine runway, males0.40.41.1-0.6-0.10.0-0.1-0.30.10.10.30.10.5-0.80.40.50.60.81.0-0.80.7-1.0-1.0-1.00.9
Latency to leave start box in cocaine runway1.11.53.51.11.31.3-1.5-1.9-1.4-1.21.60.91.7-1.81.51.31.40.90.6-1.00.8-0.0-0.2-0.60.6
Latency to leave start box in cocaine runway, F0.81.02.00.40.60.5-0.6-1.1-0.5-0.41.00.61.1-1.11.11.21.31.21.0-1.41.3-1.0-1.2-1.31.3
Latency to leave start box in cocaine runway, M3.13.06.92.12.22.3-2.5-2.6-2.5-2.02.01.32.2-2.51.81.41.30.50.1-0.40.11.41.10.3-0.4
Std. dev. time between licks in bursts0.20.41.3-0.3-0.4-0.00.0-0.20.10.10.1-0.90.9-0.7-0.5-0.6-0.3-0.0-1.00.7-1.20.80.70.6-1.0
Total sessions with >9 infusions0.81.03.5-0.3-0.5-0.60.91.00.60.6-0.70.8-1.21.0-0.10.30.10.71.3-1.01.4-1.9-1.8-1.31.4
Short access day 1 total inactive lever presses0.20.42.01.00.60.5-0.30.1-0.7-0.5-0.11.4-0.90.60.20.40.20.50.8-0.71.0-0.7-0.7-0.40.5
Short access day 10 total inactive lever presses0.00.21.00.2-0.3-0.40.30.6-0.0-0.1-0.40.4-0.81.0-0.2-0.1-0.10.00.5-0.20.4-0.6-0.5-0.30.4
Short access day 1 total infusions0.10.30.90.40.20.00.10.2-0.3-0.1-0.00.7-0.50.60.20.40.30.40.5-0.71.0-0.9-0.8-0.60.7
Short access day 10 total infusions0.71.23.8-0.9-1.2-1.31.51.61.31.3-1.5-0.4-1.91.9-1.1-0.9-1.0-0.8-0.40.30.1-0.8-0.6-0.00.3
Short access total infusions0.60.92.6-0.7-0.9-1.01.31.30.90.9-1.00.1-1.51.6-0.7-0.3-0.4-0.10.3-0.40.8-1.4-1.2-0.70.9
Short access day 1 locomotion0.00.00.10.20.10.1-0.0-0.1-0.0-0.2-0.10.0-0.10.2-0.2-0.2-0.2-0.3-0.30.2-0.10.20.20.3-0.3
Short access day 10 total locomotion0.10.31.10.50.2-0.10.10.20.20.0-0.10.8-0.50.40.30.50.30.50.7-0.71.1-1.0-0.9-0.71.0
Short access total locomotion0.20.31.10.0-0.4-0.50.60.70.50.4-0.70.2-1.11.0-0.4-0.2-0.3-0.20.1-0.20.5-0.7-0.6-0.30.5
One hour access (0.3 mA shock)0.70.82.51.61.51.2-1.1-1.0-1.1-1.21.01.10.5-0.60.90.70.60.4-0.1-0.20.30.80.70.4-0.3
Compulsive drug intake1.01.52.71.41.51.5-1.3-1.0-1.2-1.41.21.61.0-0.91.41.41.21.51.5-1.11.2-0.3-0.4-0.70.7
One hour access (shock baseline)0.10.31.40.1-0.1-0.40.30.10.20.3-0.3-0.4-0.50.4-0.4-0.5-0.5-0.9-1.20.6-0.50.50.60.7-0.5
Social response proportion0.70.92.80.90.80.8-0.7-0.8-0.7-0.80.4-0.10.2-0.9-0.2-0.5-0.4-0.7-1.20.9-1.01.71.61.5-1.5
Social responses0.00.00.10.30.20.2-0.1-0.2-0.2-0.40.20.00.2-0.10.1-0.00.00.1-0.10.1-0.10.30.30.2-0.3
Social time0.40.61.40.70.90.6-0.7-0.7-0.7-0.60.61.10.2-0.40.90.90.80.90.9-1.01.2-0.7-0.7-0.70.9
Soleus weight9.528.152.36.16.66.8-6.9-7.1-6.4-6.67.04.97.1-7.25.95.15.54.02.0-3.32.01.80.9-1.30.2
Bone: stiffness1.01.92.81.41.51.4-1.3-1.5-1.4-1.41.41.60.8-1.31.51.51.51.41.3-1.71.7-0.9-1.1-1.21.2
Tibialis anterior weight9.733.455.17.07.17.4-7.3-7.3-7.1-7.27.36.27.1-6.86.55.96.14.83.4-4.33.10.9-0.1-2.21.0
Time to tail flick, vehicle, before self-admin1.11.35.1-2.3-1.7-1.61.41.11.61.7-1.0-1.9-0.20.5-1.1-1.0-0.8-0.6-0.60.7-0.9-0.2-0.10.1-0.1
Time to tail flick, vehicle, after self-admin0.00.10.20.40.20.3-0.3-0.4-0.3-0.1-0.10.3-0.40.2-0.0-0.0-0.1-0.2-0.10.10.00.20.20.2-0.2
Time to tail flick, test, before self-admin3.23.66.3-1.6-1.7-1.41.21.21.21.5-1.7-2.3-1.51.2-2.2-2.3-2.2-2.4-2.52.4-2.51.71.82.1-2.1
Time to tail flick, test, after self-admin1.31.43.2-1.2-1.5-1.71.61.81.51.4-1.5-1.0-1.61.5-1.2-1.0-1.1-0.8-0.40.5-0.1-0.7-0.50.10.3
Delta time to tail flick, vehicle, before/after SA0.20.31.51.20.70.6-0.6-0.5-0.8-0.60.11.0-0.50.30.30.30.1-0.10.1-0.20.50.00.00.10.1
Delta time to tail flick, test, before/after SA0.81.02.51.31.00.5-0.5-0.2-0.7-0.80.61.40.3-0.11.11.21.01.01.3-1.21.6-1.0-1.0-1.01.3
Tibia length0.51.44.51.30.90.9-0.7-0.6-0.7-0.90.1-0.3-0.1-0.2-0.2-0.6-0.7-1.7-1.71.3-1.32.12.11.9-1.7
Ambulatory time before self-admin0.10.20.5-0.5-0.4-0.50.50.20.50.7-0.5-0.4-0.60.1-0.3-0.2-0.20.0-0.1-0.10.3-0.5-0.5-0.20.5
Ambulatory time after self-admin1.32.14.01.91.91.8-1.5-1.4-1.5-1.51.42.00.7-1.11.61.61.51.61.3-1.51.6-0.5-0.6-0.90.9
Bone: tissue strength0.50.51.6-0.6-0.7-0.80.91.00.80.7-1.0-0.5-1.30.8-0.8-0.8-0.9-0.5-0.30.6-0.3-0.10.10.4-0.2
Total heroin consumption0.60.71.90.30.70.9-0.9-1.0-0.3-0.61.10.51.2-1.40.90.91.11.10.9-1.00.7-0.4-0.6-0.80.6
Bone: trabecular number0.81.42.7-1.5-1.6-1.41.51.41.41.4-1.4-1.3-1.41.0-1.5-1.4-1.3-1.2-0.90.9-0.9-0.10.00.4-0.5
Bone: trabecular spacing0.00.00.20.00.30.1-0.1-0.1-0.1-0.00.20.10.20.10.40.40.20.10.2-0.20.3-0.1-0.1-0.20.4
Bone: trabecular thickness0.10.20.90.90.60.6-0.5-0.2-0.7-0.70.11.0-0.5-0.00.10.1-0.0-0.20.00.00.20.30.30.3-0.3
Bone: trabecular tissue density5.08.817.64.24.13.9-4.0-3.7-3.9-3.93.53.62.9-2.93.22.82.82.21.6-2.01.80.70.3-0.50.3
Water consumed over 24 hours0.10.10.4-0.0-0.2-0.20.20.40.20.3-0.5-0.2-0.60.4-0.3-0.3-0.5-0.6-0.50.5-0.20.30.30.4-0.2
Number of responses in last shaping day0.00.10.30.60.20.3-0.10.1-0.2-0.40.00.5-0.20.00.00.10.10.20.4-0.00.00.00.0-0.0-0.1