Hub : Genes

Tex9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Tex9 0.37 0.2 1.4e-03 0.16 0.15 0.11 0.17 4.2e-05 1.0e-04 9.0e-04 2.8e-05
2 pVTA gene expression Tex9 0.31 0.11 0.0e+00 0.24 0.25 0.24 0.24 2.8e-19 2.0e-20 2.8e-19 1.4e-19
3 Brain gene expression Tex9 0.41 0.12 0.0e+00 0.3 0.29 0.3 0.31 1.1e-28 1.7e-27 3.8e-28 6.6e-29
4 Brain alternative TSS XM_006243344.5 0.03 0.02 3.8e-03 0.04 0.03 0.02 0.03 1.4e-04 1.2e-03 5.3e-03 5.7e-04
5 BLA gene expression Tex9 0.14 0.08 1.2e-05 0.09 0.09 0.07 0.08 1.3e-05 2.6e-05 9.2e-05 4.5e-05
6 NAcc gene expression Tex9 0.15 0.07 2.2e-15 0.11 0.1 0.11 0.11 3.8e-16 6.9e-15 1.1e-15 1.0e-15
7 Liver gene expression Tex9 0.3 0.12 0.0e+00 0.24 0.23 0.23 0.23 9.6e-27 4.1e-25 1.2e-25 1.2e-25
8 IC gene expression Tex9 0.16 0.09 2.2e-05 0.1 0.12 0.12 0.12 5.2e-05 8.0e-06 1.3e-05 1.4e-05
9 Adipose gene expression Tex9 0.56 0.08 0.0e+00 0.31 0.43 0.43 0.43 7.8e-35 2.3e-52 2.7e-51 1.5e-51
10 PL alternative polyA XM_039082508.2 0.04 0.03 3.5e-03 0.02 0.02 0.02 0.02 1.2e-03 2.2e-03 5.5e-03 3.4e-03
11 PL gene expression Tex9 0.09 0.05 3.8e-09 0.09 0.07 0.07 0.07 1.3e-09 2.1e-08 5.8e-08 1.8e-08
12 Liver alternative TSS XM_006243344.5 0.09 0.05 8.1e-08 0.02 0.04 0.02 0.03 2.6e-03 4.8e-05 1.4e-03 4.1e-04
13 Liver alternative polyA NM_001399268.1 0.05 0.04 6.9e-04 0.01 0.02 0.01 0.01 1.1e-02 3.0e-03 1.8e-02 1.1e-02
14 Liver alternative polyA NM_001399268.1 0.03 0.02 4.9e-03 0 0.01 -0 0 1.0e-01 3.6e-02 4.2e-01 1.1e-01
15 PL alternative polyA XM_006243344.5 0.04 0.03 8.2e-04 0.02 0.02 0.02 0.03 5.7e-03 2.3e-03 1.1e-03 5.8e-04
16 Liver alternative polyA XM_006243344.5 0.04 0.03 2.4e-03 0.01 0.01 0.01 0.01 7.7e-03 1.1e-02 2.1e-02 2.2e-02
17 NAcc alternative polyA XM_039082508.2 0.02 0.01 1.2e-03 0.01 0.01 0.01 0.01 1.8e-03 1.7e-03 6.1e-03 2.6e-03
18 IC alternative polyA XM_006243344.5 0.1 0.11 6.5e-03 0.02 0.03 0.03 0.04 3.3e-02 1.5e-02 2.6e-02 1.3e-02
19 PL alternative TSS XM_006243344.5 0.04 0.03 9.0e-04 0.02 0.03 0.02 0.02 1.0e-03 7.4e-04 4.5e-03 3.2e-03
20 Adipose isoform ratio XM_039082508.2 0.1 0.05 1.1e-11 0.06 0.08 0.07 0.08 4.0e-07 1.8e-09 9.3e-09 7.4e-09
21 Adipose alternative polyA XM_039082508.2 0.1 0.06 3.7e-12 0.05 0.08 0.06 0.07 5.6e-06 3.3e-09 1.4e-07 1.9e-08
22 Adipose alternative TSS XM_063265174.1 0.05 0.04 1.0e-03 0.01 0.01 0.01 0.01 4.4e-02 6.9e-03 6.0e-02 4.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.20.40.7-0.5-0.7-0.5-0.5-0.6-0.4-0.5-0.7-0.50.8-0.3-0.8-0.8-0.7-0.70.60.7-0.7-0.70.30.30.5
Area under the delay curve0.40.51.60.20.00.1-0.2-0.20.00.1-0.2-0.5-0.0-0.1-0.4-0.6-0.6-0.80.71.0-0.9-1.11.31.31.1
BMI with tail4.214.427.04.65.15.14.94.95.05.05.03.4-5.24.64.23.43.51.8-0.8-1.50.90.62.62.00.3
BMI without tail1.34.09.51.82.62.42.32.52.32.32.81.6-3.12.42.52.22.31.3-0.8-1.41.00.90.70.3-0.6
Body weight2.410.420.94.14.34.34.34.44.34.34.22.2-4.64.23.12.22.50.50.6-0.5-0.2-0.53.22.61.2
Weight adjusted by age3.95.910.12.32.82.63.23.22.82.33.02.5-2.83.22.92.72.72.0-1.5-2.12.21.7-0.1-0.5-1.3
Bone surface0.10.10.40.40.30.50.40.50.40.40.40.4-0.30.70.30.30.30.3-0.2-0.30.10.1-0.0-0.1-0.2
Bone volume0.10.10.50.50.40.50.40.50.50.50.30.3-0.00.70.10.00.1-0.10.20.1-0.2-0.20.40.30.2
Breakpoint value in progressive ratio session0.00.10.3-0.20.10.1-0.10.2-0.40.10.3-0.3-0.50.50.20.10.10.1-0.0-0.0-0.2-0.10.20.10.0
Number of licking bursts1.11.73.8-1.9-1.8-1.9-1.8-1.6-1.8-2.0-1.5-1.01.5-1.5-1.0-0.6-0.70.1-0.10.00.40.3-1.5-1.3-0.8
Context. condit. distance diff. score0.50.61.3-0.1-0.3-0.2-0.3-0.5-0.1-0.1-0.7-0.40.8-0.5-0.9-1.0-1.0-0.91.11.1-1.1-1.00.91.01.1
Locomotion velocity, session 12.52.74.51.01.51.31.21.51.21.11.71.7-1.41.12.02.12.02.0-2.1-2.02.02.0-1.2-1.4-1.8
Locomotion distance, session 10.30.30.9-0.7-0.4-0.5-0.7-0.5-0.7-0.6-0.40.10.5-0.20.00.20.10.4-0.9-0.40.80.7-1.0-0.9-0.7
Locomotion velocity, session 20.10.10.3-0.40.2-0.10.10.3-0.1-0.20.5-0.5-0.50.30.40.40.50.1-0.3-0.60.30.5-0.4-0.4-0.3
Locomotion distance, session 20.20.30.6-0.50.1-0.1-0.00.2-0.2-0.10.50.0-0.60.70.60.60.60.5-0.8-0.70.70.7-0.7-0.7-0.8
Locomotion velocity, session 31.11.24.3-0.9-0.2-0.5-0.6-0.4-0.6-0.50.10.40.0-0.30.60.90.80.9-1.3-1.51.81.8-2.1-2.0-1.7
Locomotion distance, session 31.81.94.5-2.1-1.9-2.0-1.9-1.8-1.9-2.0-1.7-1.21.5-1.5-1.2-0.9-1.0-0.50.20.30.2-0.0-1.2-0.9-0.4
Stereotopy head waving bouts, day 30.80.91.91.41.21.11.21.01.21.21.01.3-0.80.51.01.00.90.7-0.8-0.80.80.8-0.1-0.2-0.4
Stereotopy head waving duration, day 31.41.73.81.91.71.71.61.51.71.71.41.8-0.90.91.41.31.30.9-0.9-1.11.01.0-0.0-0.2-0.5
Locomotion velocity, session 70.70.71.8-1.1-0.9-1.1-1.0-1.1-1.0-1.1-1.1-0.81.4-0.8-0.9-0.8-0.9-0.60.40.5-0.5-0.2-0.3-0.10.3
Locomotion distance, session 71.01.23.0-1.7-1.4-1.5-1.5-1.5-1.5-1.5-1.3-1.01.5-1.0-0.9-0.6-0.7-0.1-0.10.00.10.3-1.2-1.0-0.5
Stereotopy head waving bouts, day 71.01.11.70.71.00.91.01.01.10.91.21.2-1.21.11.31.31.31.0-0.9-1.21.21.1-0.5-0.7-1.0
Stereotopy head waving duration, day 71.31.62.60.81.10.91.01.11.10.91.31.5-1.11.01.41.51.51.3-1.4-1.61.61.6-1.1-1.2-1.4
Locomotion velocity, session 80.50.61.40.00.40.40.40.60.10.30.80.4-0.80.80.70.80.90.8-0.9-1.20.81.0-0.9-1.0-1.0
Locomotion distance, session 80.30.51.8-1.3-1.0-1.0-1.0-0.9-1.0-1.0-0.7-0.90.6-0.3-0.7-0.6-0.5-0.30.10.2-0.2-0.2-0.5-0.4-0.1
Degree of sensitization distance0.00.00.2-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.2-0.10.5-0.0-0.1-0.1-0.10.1-0.2-0.1-0.20.2-0.2-0.2-0.1
Degree of sensitization stereotypy0.80.81.40.50.90.80.90.90.90.71.01.1-1.00.81.21.21.10.9-0.8-1.01.11.0-0.5-0.6-0.9
Conditioned locomotion1.21.34.50.40.40.30.30.10.40.3-0.1-0.60.3-0.1-0.5-0.9-0.9-1.71.81.5-1.6-1.52.12.12.0
Cocaine response after cond. corrected3.74.58.12.82.82.72.72.42.72.72.42.7-1.72.02.42.22.11.7-1.5-1.61.51.50.2-0.1-0.7
Cocaine response after cond. not corrected2.73.26.42.52.42.32.32.12.22.42.02.4-1.21.92.01.81.71.4-1.3-1.31.11.20.20.0-0.5
Cocaine response before conditioning0.91.11.9-1.2-1.2-1.1-1.1-1.0-1.2-1.2-1.1-1.41.0-0.4-1.1-1.1-1.1-1.21.01.2-1.1-1.10.50.60.8
Saline control response0.60.82.00.40.40.30.30.40.30.30.31.10.10.70.70.90.80.9-1.2-1.21.41.4-1.3-1.3-1.2
Bone: connectivity density0.91.43.2-1.8-1.8-1.6-1.7-1.6-1.5-1.6-1.3-1.01.1-1.1-1.2-0.8-0.8-0.4-0.10.10.10.0-1.3-1.1-0.6
Bone: cortical apparent density0.50.71.7-1.0-0.9-1.1-1.1-1.2-1.1-1.1-1.1-0.61.2-1.3-0.7-0.6-0.7-0.2-0.10.30.00.0-0.5-0.4-0.0
Bone: cortical area0.71.13.92.01.61.41.41.01.61.50.61.30.30.60.50.30.1-0.50.60.2-0.30.11.11.11.0
Bone: cortical porosity0.91.01.7-0.6-0.8-0.9-0.9-0.7-0.9-0.8-1.0-1.21.0-0.4-1.2-1.3-1.3-1.21.11.1-1.3-1.00.60.81.1
Bone: cortical porosity2.02.14.2-1.0-1.2-1.1-1.1-1.0-1.1-1.1-1.3-1.91.0-0.8-1.7-1.8-1.8-1.81.81.7-2.0-1.71.11.31.7
Bone: cortical thickness0.40.62.40.50.0-0.2-0.2-0.6-0.0-0.0-0.90.21.5-1.0-0.8-0.8-1.1-1.01.00.9-0.7-0.40.70.91.2
Bone: cortical thickness0.20.20.80.50.10.0-0.1-0.30.00.1-0.40.10.9-0.4-0.4-0.5-0.6-0.50.70.4-0.4-0.10.30.40.7
Bone: cortical tissue density0.50.71.7-1.1-1.0-1.2-1.1-1.2-1.1-1.2-1.1-0.71.2-1.3-0.7-0.6-0.7-0.2-0.10.30.10.0-0.6-0.4-0.1
Condit. Reinf. active minus inactive responses1.92.15.6-1.8-1.5-1.3-1.3-1.2-1.4-1.4-1.0-2.40.1-1.0-1.4-1.5-1.3-1.41.71.7-1.8-2.01.11.21.2
Condit. Reinf. active-inactive response ratio1.71.83.8-0.4-0.8-0.6-0.7-0.8-0.7-0.6-1.1-1.40.8-0.9-1.4-1.6-1.5-1.61.91.9-1.9-2.01.71.81.8
Condit. Reinf. active responses0.81.04.0-2.0-1.3-1.2-1.2-1.0-1.3-1.3-0.5-1.8-0.5-0.8-0.7-0.7-0.5-0.20.60.6-0.8-1.00.10.10.1
Condit. Reinf. inactive responses1.11.44.0-1.6-0.6-0.7-0.7-0.3-0.8-0.80.4-0.3-0.8-0.20.50.81.01.6-1.5-1.51.31.2-2.0-2.0-1.9
Incentive salience index mean1.82.25.7-1.6-1.2-1.1-1.1-0.9-1.2-1.2-0.8-2.4-0.0-0.8-1.3-1.5-1.3-1.51.91.8-2.1-2.11.51.61.5
Condit. Reinf. lever presses1.11.54.0-1.4-0.8-0.9-0.8-0.6-1.0-0.9-0.6-2.00.1-0.5-1.1-1.3-1.1-1.21.71.5-1.9-1.71.31.41.4
Condit. Reinf. active minus inactive responses1.21.54.71.31.31.51.61.81.41.51.80.8-1.72.21.21.01.31.1-0.2-0.70.30.10.50.3-0.3
Condit. Reinf. active-inactive response ratio1.31.53.41.81.61.71.81.81.61.71.51.2-0.91.71.00.80.90.7-0.1-0.40.10.10.90.70.2
Condit. Reinf. active responses0.60.84.10.70.71.11.11.40.90.91.20.0-1.32.00.60.30.60.40.50.1-0.4-0.71.00.80.3
Condit. Reinf. inactive responses0.60.82.3-1.5-1.3-0.9-1.0-0.7-1.0-1.2-0.7-1.5-0.00.0-0.9-0.9-0.7-0.71.00.8-0.9-1.10.30.30.3
Condit. Reinf. lever presses0.40.51.50.0-0.3-0.2-0.1-0.3-0.2-0.2-0.6-0.51.1-0.2-0.8-0.8-0.8-0.71.20.9-1.0-0.80.80.81.0
Condit. Reinf. lever reinforcers received0.50.73.00.60.60.91.01.20.80.81.0-0.1-1.01.70.30.10.30.10.80.3-0.6-0.81.21.00.6
Conditioned reinforcement - actives0.00.10.30.50.30.1-0.10.00.20.40.20.50.2-0.00.20.20.20.2-0.3-0.30.20.4-0.1-0.2-0.2
Conditioned reinforcement - inactives0.20.31.20.90.50.4-0.1-0.40.40.70.21.10.4-0.20.40.50.30.6-0.9-0.50.50.7-0.4-0.4-0.4
Conditioned locomotion0.81.12.2-0.1-0.4-0.5-0.8-0.7-0.5-0.2-0.7-0.80.9-0.6-1.1-1.2-1.2-1.31.51.4-1.5-1.41.31.31.4
Patch foraging indifference point 0 sec0.30.51.30.20.60.30.50.50.50.20.70.6-0.60.60.91.00.90.7-0.7-1.01.11.1-0.7-0.8-0.8
Patch foraging indifference point AUC1.21.75.0-2.2-1.9-1.7-1.8-1.4-1.9-1.7-1.1-2.1-0.0-0.6-1.2-1.1-0.9-0.80.60.9-0.9-1.2-0.10.00.1
Delay disc. indifference point, 0s delay1.41.53.1-1.6-1.6-1.4-1.7-1.6-1.5-1.4-1.3-1.80.7-0.8-1.3-1.3-1.2-0.90.81.2-0.9-1.20.30.40.6
Delay disc. indifference point, 16s delay1.11.33.40.2-0.2-0.0-0.2-0.3-0.0-0.0-0.6-0.80.5-0.5-0.9-1.2-1.2-1.61.41.6-1.6-1.61.81.81.8
Delay disc. indifference point, 2s delay0.10.10.30.1-0.3-0.2-0.4-0.4-0.2-0.1-0.50.10.5-0.4-0.3-0.3-0.30.1-0.30.20.1-0.1-0.1-0.10.0
Delay disc. indifference point, 24s delay0.30.30.8-0.2-0.3-0.3-0.4-0.4-0.3-0.2-0.5-0.50.4-0.4-0.6-0.7-0.7-0.90.60.7-0.7-0.70.60.60.7
Delay disc. indifference point, 4s delay1.21.32.6-0.4-0.8-0.6-1.0-0.9-0.7-0.5-0.9-1.20.5-0.9-1.2-1.3-1.3-1.31.41.5-1.4-1.61.31.41.5
Delay disc. indifference point, 8s delay0.20.20.80.30.40.50.20.00.30.40.3-0.0-0.60.40.20.10.1-0.10.10.4-0.4-0.60.90.80.5
Indifference point function ln k1.62.87.02.72.32.12.22.02.22.21.72.3-0.91.41.81.61.51.2-1.0-1.21.31.30.20.0-0.4
Indifference point function log k1.62.87.02.72.32.12.22.02.22.21.72.3-0.91.41.81.61.51.2-1.0-1.21.31.30.20.0-0.4
Patch foraging total patch changes 0 sec0.40.81.60.40.90.50.70.70.60.40.90.8-0.80.81.11.11.00.8-0.8-1.11.31.2-0.7-0.8-0.9
Patch foraging total patch changes 12 sec0.30.41.4-1.2-0.9-1.0-1.0-0.9-0.9-1.0-0.7-0.70.2-0.2-0.5-0.4-0.4-0.3-0.00.1-0.1-0.0-0.6-0.5-0.4
Patch foraging total patch changes 18 sec0.00.10.2-0.4-0.2-0.3-0.3-0.3-0.3-0.4-0.0-0.2-0.30.10.20.20.2-0.0-0.2-0.20.30.3-0.3-0.3-0.4
Patch foraging total patch changes 24 sec0.40.82.3-1.0-0.5-0.6-0.6-0.3-0.7-0.70.1-0.0-0.30.00.50.70.70.9-1.0-1.01.31.0-1.5-1.5-1.5
Patch foraging total patch changes 6 sec0.30.41.8-1.4-0.7-0.7-0.6-0.4-0.8-0.9-0.1-0.7-0.50.10.10.20.30.3-0.4-0.40.50.2-0.8-0.8-0.9
Patch foraging time to switch 0 sec0.81.63.2-0.8-1.0-0.8-1.1-1.2-0.9-1.0-1.4-1.11.8-1.4-1.6-1.6-1.6-1.51.51.2-1.6-1.00.50.71.3
Patch foraging water rate 0 sec1.53.14.91.82.01.72.02.01.91.82.11.8-2.21.92.22.12.01.7-1.6-1.51.71.4-0.2-0.5-1.1
Patch foraging water rate 12 sec3.67.510.92.62.72.52.82.92.82.72.93.3-2.72.53.23.23.23.3-3.1-2.82.92.5-1.2-1.5-2.3
Patch foraging water rate 18 sec0.71.12.01.11.01.01.21.31.31.11.01.4-0.71.21.21.21.10.9-1.0-1.01.30.9-0.4-0.5-0.8
Patch foraging water rate 24 sec0.60.82.6-0.1-0.2-0.3-0.10.1-0.10.00.20.7-0.30.30.50.80.81.3-1.6-1.01.41.0-1.4-1.4-1.5
Patch foraging water rate 6 sec1.11.73.01.01.00.91.11.21.00.91.31.4-1.51.31.51.61.61.7-1.7-1.31.61.1-0.7-0.9-1.3
Seeking ratio, delayed vs. immediate footshock0.50.61.60.90.91.11.11.31.01.01.00.8-0.80.90.80.70.80.5-0.3-0.40.40.10.40.2-0.2
Distance traveled before self-admin0.00.00.3-0.00.20.00.00.40.1-0.10.10.0-0.00.50.20.20.20.3-0.1-0.30.20.3-0.2-0.2-0.2
Distance traveled after self-admin2.32.85.02.02.21.91.71.61.71.71.92.0-1.31.72.12.01.91.7-1.3-1.81.41.8-0.5-0.6-1.0
Extensor digitorum longus weight4.618.034.35.25.35.65.55.65.45.65.73.8-5.95.24.63.94.22.8-1.4-2.41.21.21.91.1-0.6
Bone: elastic displacement0.10.10.40.1-0.00.20.20.20.00.20.2-0.1-0.60.4-0.0-0.1-0.1-0.10.30.4-0.3-0.60.60.50.3
Bone: elastic work0.50.72.00.2-0.2-0.00.0-0.10.10.0-0.3-0.6-0.10.1-0.7-0.9-0.8-0.81.41.2-1.3-1.41.41.41.3
Bone: endosteal estimation1.53.36.52.22.42.42.42.62.52.32.31.6-1.92.42.11.81.80.9-0.7-1.20.70.90.60.3-0.4
Bone: endosteal perimeter2.04.39.22.82.72.92.93.03.02.82.61.6-2.42.91.91.51.60.50.1-0.60.00.11.61.20.4
Epididymis fat weight0.10.20.9-1.0-0.5-0.6-0.6-0.4-0.3-0.5-0.1-0.4-0.0-0.4-0.1-0.00.10.2-0.2-0.40.30.3-0.8-0.7-0.5
Delta time in closed arm before/after self-admin0.30.30.7-0.3-0.3-0.5-0.5-0.8-0.4-0.2-0.5-0.40.5-0.8-0.6-0.6-0.7-0.80.60.7-0.7-0.60.50.50.7
Delta time in open arm before/after self-admin0.50.52.1-0.5-0.5-0.4-0.6-0.6-0.3-0.7-0.40.40.6-0.6-0.10.20.20.7-0.7-0.81.00.9-1.5-1.4-1.1
Diff in mean of infusions in LGA sessions0.70.93.60.20.30.70.20.50.10.70.3-0.5-0.70.8-0.3-0.6-0.5-0.51.01.2-1.6-1.61.91.81.4
Delay discount exponential model param0.30.31.2-0.3-0.1-0.20.10.1-0.1-0.20.10.30.1-0.00.30.40.50.6-0.6-0.80.70.9-1.1-1.1-0.9
Extinction: sum of active levers before priming0.50.61.50.00.3-0.10.30.30.1-0.10.50.3-0.60.40.70.90.80.9-0.9-1.21.01.2-1.1-1.1-1.1
Active lever presses in extinction session 60.40.40.80.70.60.80.50.60.40.80.70.6-0.90.80.60.60.70.8-0.8-0.50.20.3-0.0-0.1-0.4
Bone: final force0.50.92.21.51.31.31.31.21.31.30.80.6-0.41.10.50.20.2-0.20.70.2-0.6-0.21.11.00.9
Bone: final moment0.50.82.11.51.11.21.11.01.21.20.50.50.00.80.2-0.1-0.1-0.61.00.5-0.8-0.41.31.31.2
Food consumed during 24 hour testing period1.72.33.31.81.71.61.61.61.61.51.51.8-1.11.41.81.81.71.4-1.5-1.51.61.6-0.6-0.8-1.2
Glucose0.81.33.00.40.70.60.60.70.50.60.91.3-1.00.51.31.41.41.6-1.7-1.31.61.3-1.0-1.1-1.4
Heart weight0.30.41.6-0.10.30.60.60.80.60.40.8-0.4-1.31.00.30.10.4-0.20.60.3-0.5-0.91.00.80.3
Delay discount hyperbolic model param0.40.41.4-0.20.1-0.00.30.30.0-0.10.30.5-0.10.20.50.60.70.8-0.7-1.00.91.1-1.2-1.2-1.1
Intermittent access intake day 1-15 change0.30.72.70.80.40.3-0.2-0.20.20.80.21.20.4-0.20.60.80.61.1-1.6-0.90.91.1-1.0-1.0-1.0
Intermittent access intake escalation0.30.62.01.00.60.60.00.10.41.00.31.30.3-0.10.60.70.61.0-1.4-0.80.60.9-0.6-0.7-0.7
Intermittent access intake escalation 20.60.62.11.51.11.00.70.70.91.40.81.2-0.30.30.90.80.70.7-0.7-0.50.40.60.20.1-0.2
Intermitt. access day 1 inactive lever presses0.10.52.70.1-0.4-0.6-0.9-1.4-0.4-0.2-0.90.11.3-1.6-0.7-0.7-0.8-0.60.20.7-0.3-0.40.30.40.6
Intermitt. access day 15 inactive lever presses0.20.41.51.20.80.80.50.50.61.10.70.9-0.40.30.60.50.50.4-0.6-0.20.00.10.40.30.0
Intermitt. access escalation Index0.30.51.20.30.40.31.01.10.70.30.6-0.6-1.11.00.3-0.00.1-0.60.80.4-0.4-0.71.00.90.7
Intermittent access day 1 total infusions0.50.82.7-0.6-0.8-1.0-1.2-1.3-1.0-0.9-1.2-0.31.6-1.6-0.9-0.7-0.8-0.50.20.2-0.20.2-0.6-0.50.1
Intermittent access day 15 total infusions0.40.52.5-0.1-0.6-0.7-1.2-1.0-0.7-0.3-1.00.01.6-1.4-0.8-0.6-0.7-0.2-0.20.2-0.30.1-0.5-0.40.0
Intermittent access terminal intake (last 3 days)0.40.52.20.2-0.3-0.4-0.8-0.8-0.4-0.1-0.90.11.5-1.4-0.8-0.7-0.8-0.60.40.6-0.6-0.30.20.30.6
Intermittent access total infusions0.30.31.40.0-0.2-0.5-0.8-0.7-0.3-0.3-0.60.41.2-1.2-0.3-0.1-0.2-0.0-0.2-0.30.40.7-0.8-0.7-0.4
Intermittent access day 1 locomotion1.11.44.1-0.9-1.4-1.4-1.6-1.5-1.3-1.3-1.7-0.72.0-2.0-1.4-1.2-1.3-0.70.40.6-0.6-0.2-0.6-0.40.2
Intermittent access day 15 total locomotion0.20.41.90.5-0.3-0.5-0.8-0.8-0.3-0.1-0.80.01.4-1.2-0.7-0.7-0.8-0.60.60.6-0.5-0.20.20.30.6
Intermittent access total locomotion0.10.10.30.50.20.1-0.10.00.10.2-0.00.60.4-0.30.10.20.10.3-0.2-0.30.30.4-0.3-0.3-0.2
Intermittent access standard deviation0.20.41.11.00.70.4-0.2-0.10.30.80.31.00.3-0.50.60.60.40.5-0.8-0.70.51.0-0.5-0.5-0.4
Left kidney weight1.77.812.93.43.53.63.53.43.63.43.43.3-3.02.83.22.92.92.4-1.8-2.01.91.60.4-0.0-1.0
Right kidney weight1.67.110.92.42.93.03.03.13.02.73.22.9-3.32.93.23.13.22.8-2.2-2.42.31.9-0.4-0.8-1.8
Cocaine induced anxiety0.60.82.0-0.3-0.4-0.5-0.6-0.5-0.6-0.5-0.6-1.10.4-0.6-0.7-0.9-0.9-1.41.41.2-1.2-1.11.11.21.2
Post-drug Anxiety1.81.94.3-1.8-1.9-1.8-2.0-1.6-2.1-1.8-1.7-1.61.5-1.7-1.4-1.1-1.2-0.90.40.7-0.4-0.4-0.7-0.5-0.0
Baseline Anxiety1.71.97.1-1.6-1.4-1.2-1.2-0.8-1.3-1.3-0.8-0.10.7-0.8-0.20.40.41.1-1.7-1.31.61.5-2.7-2.6-2.2
Tail length0.31.12.8-1.6-1.4-1.4-1.3-1.1-1.5-1.5-0.7-1.00.4-1.1-0.5-0.2-0.10.1-0.3-0.60.60.6-1.7-1.6-1.1
Length with tail0.10.31.10.60.50.60.70.90.60.50.90.2-1.00.90.60.50.70.3-0.0-0.60.30.3-0.1-0.2-0.3
Length without tail1.85.811.63.43.13.23.43.43.33.23.01.7-3.03.42.11.51.60.40.5-0.2-0.2-0.52.42.01.0
Times rat made contact with spout0.10.10.50.30.20.10.1-0.00.20.1-0.20.70.6-0.30.30.40.10.3-0.4-0.20.60.4-0.2-0.2-0.3
Lifetime Intake0.20.31.20.0-0.2-0.5-0.8-0.7-0.3-0.3-0.50.41.1-1.0-0.2-0.0-0.20.0-0.2-0.30.40.7-0.8-0.7-0.4
Liver weight, left2.74.47.81.92.32.32.22.42.22.22.62.2-2.82.12.72.52.52.3-1.8-1.81.81.3-0.1-0.4-1.4
Liver weight, right1.01.82.71.41.61.61.31.51.51.51.61.6-1.51.41.61.51.61.5-1.1-1.21.11.0-0.1-0.4-0.9
Locomotor activity3.45.310.43.13.13.03.23.23.13.02.92.3-2.72.82.52.02.11.1-0.5-1.20.80.81.10.8-0.0
Locomotor testing distance2.74.98.42.92.92.82.92.82.92.72.72.7-2.32.22.52.22.21.6-1.2-1.51.41.20.50.2-0.6
Locomotor testing rearing0.61.32.81.21.11.31.31.31.31.31.41.2-1.71.11.31.21.31.3-1.0-0.90.80.50.0-0.2-0.7
Locomotion in novel chamber0.20.20.70.30.10.0-0.5-0.8-0.1-0.1-0.40.20.8-0.6-0.3-0.3-0.5-0.50.40.5-0.2-0.30.50.50.6
Locomotion in novel chamber post-restriction0.50.91.9-0.8-0.9-0.8-0.7-0.8-0.8-0.6-0.8-1.20.5-0.6-1.1-1.1-1.0-0.81.01.1-1.4-1.20.70.80.9
Fecal boli incidents, locomotor time 10.50.82.0-0.8-0.8-0.7-0.4-0.3-0.8-0.7-0.8-1.40.4-0.5-0.9-1.0-1.0-1.41.21.0-0.9-1.00.60.70.9
Change in fecal boli incidents, locomotor task2.22.14.82.11.81.51.00.91.61.51.42.2-0.60.61.81.81.61.5-1.6-1.51.51.7-0.6-0.8-1.0
Time >=10cm from walls, locomotor time 10.30.31.20.60.60.60.50.40.50.70.30.4-0.00.00.1-0.0-0.10.00.20.5-0.7-0.61.11.00.8
Bouts of movement, locomotor time 10.10.10.3-0.10.30.20.20.3-0.0-0.00.4-0.3-0.60.50.40.30.30.10.3-0.10.00.00.30.30.1
Total resting periods, locomotor time 10.10.10.3-0.10.30.10.20.3-0.0-0.10.4-0.2-0.40.50.40.30.30.10.2-0.20.10.20.10.1-0.0
Rest time, locomotor task time 10.40.51.8-0.00.3-0.1-0.10.1-0.1-0.3-0.1-0.80.2-0.3-0.2-0.4-0.5-1.21.30.8-1.0-0.71.11.21.2
Distance moved, locomotor task time 10.20.30.9-0.8-0.8-0.6-0.5-0.9-0.5-0.5-0.5-0.00.3-0.6-0.4-0.1-0.10.7-0.7-0.30.40.3-1.0-0.9-0.7
Vertical activity count, locomotor time 10.10.20.6-0.6-0.8-0.6-0.3-0.8-0.4-0.4-0.5-0.50.3-0.5-0.7-0.6-0.50.1-0.00.4-0.3-0.5-0.0-0.00.1
Time >=10cm from walls, locomotor time 20.10.10.40.20.30.10.10.40.40.20.10.1-0.00.10.20.1-0.0-0.20.10.3-0.2-0.30.60.60.5
Bouts of movement, locomotor time 20.40.61.10.10.60.60.70.90.50.40.90.5-1.01.01.01.01.00.7-0.7-0.81.00.7-0.4-0.6-0.9
Total resting periods, locomotor time 20.50.81.50.20.70.60.80.90.60.41.00.7-1.01.11.21.21.20.9-0.9-1.11.20.9-0.6-0.7-1.1
Rest time, locomotor task time 20.10.10.4-0.1-0.0-0.3-0.5-0.2-0.6-0.5-0.3-0.50.4-0.5-0.2-0.2-0.4-0.60.60.3-0.3-0.00.20.30.4
Distance moved, locomotor task time 20.30.41.4-0.8-0.5-0.4-0.1-0.2-0.1-0.3-0.10.1-0.10.0-0.00.20.41.1-0.9-0.70.70.6-1.2-1.2-1.0
Vertical activity count, locomotor time 20.40.51.3-1.0-1.1-1.0-0.4-0.8-0.6-0.8-0.8-0.41.0-0.5-0.7-0.4-0.40.3-0.6-0.20.40.3-1.1-1.0-0.6
Light reinforcement 10.92.38.21.31.91.81.92.11.81.82.10.6-2.91.91.61.11.30.50.3-0.1-0.1-0.41.71.40.5
Light reinforcement 20.10.20.80.40.20.1-0.1-0.2-0.10.0-0.30.00.5-0.5-0.1-0.2-0.4-0.90.60.4-0.2-0.10.50.50.7
Bone: marrow area1.63.46.82.32.42.52.52.62.52.42.31.7-1.92.42.11.81.80.9-0.7-1.20.60.90.60.3-0.3
Bone: maximum diameter2.54.710.63.33.13.03.02.93.13.02.52.3-1.92.42.21.91.70.7-0.5-1.00.61.01.10.80.2
Bone: maximum force0.50.91.91.41.21.31.31.31.41.20.90.5-0.51.10.40.10.2-0.30.90.2-0.7-0.41.21.10.9
Bone: maximum moment0.50.91.91.41.21.21.21.11.31.20.60.4-0.10.80.2-0.1-0.1-0.61.10.5-0.9-0.51.41.31.2
Mean time between licks in bursts0.20.40.9-0.6-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.70.4-0.5-0.8-0.7-0.7-0.40.50.6-0.4-0.6-0.00.00.2
Mean num. licks in bursts1.32.05.32.32.12.02.01.72.02.11.51.7-1.11.41.31.00.90.3-0.4-0.30.20.31.21.00.5
Cd content in liver1.61.83.3-1.6-1.7-1.5-1.5-1.1-1.6-1.5-1.4-1.81.0-0.6-1.6-1.6-1.5-1.11.01.4-1.2-1.50.50.60.9
Co content in liver2.42.85.8-1.1-1.1-1.2-1.1-1.3-1.2-1.2-1.3-2.00.9-1.2-1.6-1.9-1.8-2.22.42.1-2.0-2.21.71.92.0
Cu content in liver0.20.31.00.10.10.10.20.10.20.1-0.1-0.2-0.00.0-0.4-0.5-0.5-0.50.80.8-0.7-0.91.01.00.9
Fe content in liver0.60.71.60.40.60.50.50.60.40.50.60.9-0.40.80.91.11.00.8-1.3-1.21.21.3-1.0-1.0-1.1
K content in liver0.60.51.80.60.80.91.01.11.00.81.10.6-1.31.00.70.60.70.6-0.1-0.50.30.10.20.1-0.2
Mg content in liver0.60.62.30.60.70.91.01.20.80.71.00.4-1.41.50.70.50.70.5-0.1-0.30.2-0.10.40.3-0.1
Mn content in liver0.70.82.51.61.21.11.10.81.11.20.60.7-0.10.10.30.0-0.1-0.71.00.4-0.6-0.41.31.31.2
Na content in liver3.13.37.31.52.12.02.22.41.91.82.51.3-2.72.52.22.02.11.2-0.9-1.61.31.20.0-0.3-0.9
Rb content in liver1.01.22.00.91.11.10.91.10.81.01.21.2-1.11.41.21.21.21.2-1.3-1.31.01.2-0.6-0.8-0.9
Se content in liver0.30.41.4-0.00.0-0.10.10.00.0-0.10.10.60.30.20.30.50.40.6-0.9-0.91.11.1-1.2-1.1-0.9
Sr content in liver0.80.72.2-1.1-1.1-1.1-0.9-0.8-1.0-1.1-0.6-1.50.3-0.6-0.8-0.8-0.6-1.01.00.5-0.6-0.6-0.1-0.00.2
Zn content in liver0.50.62.2-0.2-0.3-0.00.00.3-0.0-0.1-0.2-0.5-0.20.6-0.6-0.8-0.7-0.81.01.2-0.9-1.51.41.31.1
Bone: minimum diameter0.81.44.41.20.90.90.80.61.10.80.1-0.10.40.4-0.3-0.7-0.8-1.71.81.3-1.5-1.22.12.12.0
Time in familiar zone, hab. session 10.40.41.30.10.10.00.0-0.0-0.00.1-0.0-0.5-0.2-0.3-0.2-0.5-0.5-0.91.10.8-1.0-0.91.11.11.0
Time in novel zone, hab. session 10.20.20.7-0.1-0.2-0.2-0.2-0.3-0.0-0.2-0.30.40.7-0.4-0.10.10.10.5-0.8-0.50.50.6-0.9-0.8-0.6
Total zone transitions, hab. session 10.50.72.0-1.1-0.6-0.9-0.8-0.8-0.8-0.8-0.40.00.5-0.60.10.40.20.7-1.3-0.71.10.9-1.4-1.3-1.1
Total locomotion distance, hab. session 10.40.51.5-0.8-0.5-0.5-0.5-0.4-0.5-0.5-0.20.30.1-0.20.20.50.40.8-1.1-0.71.10.8-1.2-1.2-1.2
Locomotion velocity, hab. session 10.30.51.5-0.5-0.1-0.2-0.2-0.1-0.2-0.20.10.5-0.10.10.50.70.70.8-1.2-0.81.20.9-1.1-1.1-1.2
Time in familiar zone, hab. session 20.20.20.7-0.4-0.4-0.4-0.4-0.3-0.4-0.3-0.30.10.2-0.40.00.20.10.4-0.3-0.40.70.5-0.8-0.8-0.7
Time in novel zone, hab. session 20.30.30.90.90.70.70.70.40.80.70.30.50.20.50.20.0-0.1-0.30.00.3-0.4-0.20.80.70.7
Total zone transitions, hab. session 20.10.21.0-1.0-0.7-0.5-0.4-0.2-0.5-0.5-0.1-0.7-0.60.3-0.2-0.2-0.1-0.10.10.3-0.1-0.60.10.1-0.1
Total locomotion distance, hab. session 20.20.20.9-0.7-0.5-0.2-0.10.1-0.2-0.30.0-0.6-0.90.8-0.2-0.2-0.1-0.10.30.5-0.3-0.90.50.40.1
Locomotion velocity, hab. session 20.20.20.9-0.7-0.5-0.2-0.2-0.0-0.2-0.3-0.1-0.6-0.70.6-0.3-0.4-0.3-0.30.50.7-0.5-1.00.60.60.3
Novel to familiar place preference ratio0.60.61.40.90.91.01.01.01.01.00.90.1-1.11.20.40.10.3-0.30.60.2-0.6-0.51.11.00.8
Novelty place preference0.70.81.61.11.01.11.21.11.21.11.00.2-1.11.20.50.20.3-0.40.60.2-0.6-0.51.31.10.9
Time in novel zone, NPP test0.91.02.01.41.31.41.41.31.41.31.20.5-1.21.30.70.40.5-0.20.40.0-0.4-0.31.21.00.7
Total zone transitions, NPP test0.10.20.6-0.5-0.1-0.1-0.00.2-0.2-0.10.20.0-0.60.80.40.40.40.5-0.6-0.20.60.0-0.2-0.2-0.5
Total locomotion distance, NPP test0.40.51.3-0.40.00.10.20.40.0-0.00.40.4-0.91.10.70.80.81.0-1.1-0.71.00.6-0.7-0.8-1.1
Locomotion velocity, NPP test0.30.51.3-1.0-0.4-0.4-0.4-0.0-0.4-0.50.1-0.0-0.60.70.30.50.60.9-1.1-0.70.90.5-1.0-1.0-1.2
Intraocular pressure0.00.10.3-0.5-0.3-0.2-0.1-0.0-0.2-0.5-0.0-0.5-0.00.4-0.2-0.1-0.00.00.2-0.0-0.4-0.1-0.2-0.2-0.1
Delta distance traveled before/after self-admin2.83.05.62.32.22.21.81.51.92.11.92.4-1.51.42.01.91.81.7-1.5-1.51.41.5-0.2-0.5-0.9
Delta ambulatory time before/after self-admin1.82.25.82.42.12.01.61.21.72.01.62.3-1.01.01.61.51.41.3-1.2-1.21.01.20.0-0.2-0.5
Parametrial fat weight0.82.04.6-1.8-2.0-2.2-2.0-1.9-2.1-2.0-1.7-1.51.4-1.4-1.3-1.0-1.1-0.80.50.40.0-0.1-1.1-0.9-0.3
Pavlov. Cond. lever latency0.70.83.11.40.91.00.80.51.01.00.41.80.50.00.70.80.60.6-1.1-0.91.11.2-0.7-0.7-0.6
Pavlov. Cond. magazine entry latency7.39.417.5-2.5-2.7-2.4-2.4-2.2-2.4-2.2-2.4-4.11.2-1.6-3.3-3.6-3.3-3.64.23.8-4.0-4.12.83.03.3
Pavlov. Cond. change in total contacts2.62.75.6-1.5-1.3-1.3-1.2-1.0-1.2-1.1-1.1-2.30.2-0.6-1.6-1.9-1.7-1.72.42.1-2.3-2.41.71.81.9
Pavlov. Cond. index score4.35.412.2-2.6-2.4-2.3-2.2-1.8-2.3-2.2-1.9-3.50.8-1.2-2.5-2.6-2.4-2.42.92.6-2.7-2.91.51.72.0
Pavlov. Cond. latency score3.24.09.9-2.4-2.2-2.1-2.0-1.6-2.1-2.0-1.6-3.10.5-1.1-2.1-2.2-2.0-2.02.42.1-2.3-2.41.21.41.6
Pavlov. Cond. lever contacts1.51.85.2-1.6-1.2-1.2-1.0-0.7-1.2-1.2-0.8-2.3-0.1-0.1-1.2-1.4-1.2-1.31.81.5-1.8-1.81.21.31.3
Pavlov. Cond. magazine entry number6.78.515.22.52.72.42.42.22.42.22.43.9-1.41.73.23.43.23.3-3.9-3.53.73.8-2.4-2.7-3.0
Pavlov. Cond. intertrial magazine entries1.41.74.8-0.5-0.0-0.1-0.1-0.1-0.1-0.20.40.9-0.3-0.30.91.31.31.7-2.0-1.81.91.8-2.1-2.2-2.2
Pavlov. Cond. lever-magazine prob. diff.4.15.112.0-2.5-2.3-2.2-2.0-1.7-2.2-2.1-1.8-3.50.6-1.1-2.4-2.5-2.3-2.32.82.6-2.7-2.91.61.82.0
Pavlov. Cond. response bias5.56.713.1-2.1-2.2-1.9-1.9-1.6-2.0-1.8-1.9-3.60.8-1.1-2.7-3.0-2.7-2.93.63.3-3.6-3.62.52.72.9
Pavlov. Cond. lever latency0.81.12.60.80.80.80.60.70.70.80.81.4-0.70.51.11.21.11.3-1.6-1.31.41.4-1.0-1.1-1.2
Pavlov. Cond. magazine entry latency2.22.64.5-1.8-2.0-2.1-1.9-2.1-2.0-2.1-2.1-1.62.1-1.9-1.8-1.6-1.7-1.50.91.2-0.7-0.9-0.20.10.6
Pavlov. Cond. change in total contacts0.61.01.8-1.1-1.2-1.2-1.0-1.0-1.0-1.1-1.1-1.40.9-0.7-1.2-1.1-1.1-1.11.20.9-0.8-0.90.20.40.7
Pavlov. Cond. index score1.11.42.2-1.3-1.4-1.4-1.2-1.2-1.2-1.4-1.3-1.51.2-1.0-1.4-1.3-1.3-1.31.31.2-1.0-1.10.30.50.8
Pavlov. Cond. latency score0.60.81.3-1.0-1.0-1.1-0.9-1.0-1.0-1.1-1.0-1.11.0-0.8-1.0-1.0-1.0-1.01.00.9-0.7-0.80.20.40.6
Pavlov. Cond. lever contacts0.70.92.1-0.8-0.8-0.8-0.6-0.7-0.7-0.8-0.8-1.30.7-0.4-1.0-1.1-1.0-1.11.41.2-1.2-1.20.80.91.0
Pavlov. Cond. magazine entry number2.02.44.51.81.92.01.81.91.92.02.01.5-2.11.81.71.51.61.3-0.9-1.10.70.70.40.1-0.4
Pavlov. Cond. intertrial magazine entries0.61.01.80.60.80.90.60.80.70.91.01.1-1.00.61.11.21.21.3-1.0-1.21.01.1-0.8-0.9-1.2
Pavlov. Cond. lever-magazine prob. diff.1.21.62.6-1.4-1.5-1.6-1.3-1.4-1.4-1.5-1.4-1.61.3-1.1-1.5-1.4-1.4-1.41.31.2-1.0-1.10.20.40.8
Pavlov. Cond. response bias2.33.14.9-1.7-1.9-1.8-1.6-1.6-1.6-1.8-1.8-2.21.6-1.3-2.0-2.0-2.0-2.02.11.9-1.8-1.90.91.11.5
Time in closed arm before self-admin0.40.61.1-0.4-0.5-0.5-0.6-0.6-0.4-0.2-0.7-0.70.8-0.7-0.8-0.9-0.9-0.70.71.0-1.1-1.00.80.90.9
Time in closed arm after self-admin0.30.31.1-0.4-0.5-0.7-0.7-1.0-0.5-0.2-0.6-0.40.8-0.8-0.6-0.6-0.7-0.50.40.6-0.6-0.50.30.40.5
Time in open arm before self-admin1.01.12.61.31.41.31.31.61.11.31.40.6-1.41.61.10.90.90.20.0-0.40.20.20.70.50.1
Time in open arm after self-admin0.50.51.01.01.01.00.70.80.90.70.90.9-0.70.90.80.80.80.5-0.3-0.60.60.6-0.0-0.1-0.3
Bone: periosteal estimation1.53.27.12.72.62.52.52.52.72.42.01.9-1.32.21.81.51.40.5-0.3-0.80.40.80.90.70.2
Bone: periosteal perimeter1.93.37.12.72.62.62.52.52.72.52.11.8-1.62.31.81.41.40.6-0.1-0.80.40.71.00.70.3
Bone: post-yield work0.00.00.1-0.00.20.30.20.30.30.20.4-0.1-0.20.20.10.10.20.00.2-0.1-0.3-0.10.20.10.0
Progressive ratio test 1 active lever presses0.30.30.9-0.3-0.5-0.5-0.8-0.9-0.5-0.6-0.60.21.0-0.8-0.3-0.1-0.2-0.1-0.4-0.30.40.6-0.9-0.8-0.5
Progressive ratio test 1 breakpoint0.30.31.0-0.3-0.5-0.6-0.9-0.9-0.6-0.6-0.60.11.0-0.8-0.3-0.1-0.2-0.1-0.3-0.30.30.5-0.9-0.8-0.5
Progressive ratio test 1 inactive lever presses1.52.15.7-0.8-1.3-1.5-1.8-2.2-1.3-1.2-1.60.42.3-2.4-0.8-0.3-0.50.3-1.3-0.61.21.3-2.2-2.0-1.3
Progressive ratio test 2 active lever presses0.40.41.51.10.90.70.60.40.90.90.61.2-0.10.20.70.70.60.6-0.6-0.60.50.7-0.1-0.2-0.3
Progressive ratio test 2 breakpoint0.40.41.51.10.90.70.60.40.90.90.61.2-0.10.20.70.70.60.6-0.6-0.60.50.7-0.1-0.2-0.3
Progressive ratio test 2 inactive lever presses0.10.21.01.00.30.1-0.2-0.50.30.4-0.20.90.9-0.8-0.1-0.0-0.2-0.1-0.1-0.00.20.3-0.1-0.00.1
Incentive Sensitization - Responses0.71.03.21.81.41.31.30.91.71.71.01.3-0.60.60.80.50.50.4-0.10.1-0.0-0.21.21.00.6
Incentive Sensitization - Breakpoint0.70.92.71.61.31.21.30.81.61.50.91.2-0.50.50.70.50.40.4-0.10.2-0.1-0.21.11.00.6
Sum of active levers in priming session hrs 5-60.30.30.80.30.50.40.40.50.30.10.40.5-0.30.50.60.70.60.6-0.6-0.80.60.9-0.6-0.6-0.6
Progressive ratio1.93.05.7-1.3-1.3-1.2-1.1-0.9-1.3-1.0-1.3-2.11.0-1.0-1.8-2.0-1.9-2.42.32.2-2.4-2.31.71.82.0
Food seeking constrained by brief footshock1.11.42.80.40.60.20.40.50.50.40.90.9-0.90.81.31.41.41.5-1.6-1.61.71.7-1.5-1.6-1.7
Seeking ratio, punishment vs. effort5.27.511.82.12.32.22.32.32.42.02.73.0-2.52.63.13.23.23.4-3.1-3.23.33.1-2.0-2.3-2.9
Retroperitoneal fat weight0.21.03.3-1.3-0.9-1.2-1.1-0.8-1.0-1.1-0.6-0.10.4-0.50.00.30.20.6-1.0-0.91.31.1-1.8-1.7-1.4
Reaction time number correct0.71.32.11.21.11.21.21.11.41.41.31.3-1.30.91.21.11.31.5-1.3-1.00.90.7-0.2-0.4-0.8
Reaction time mean minus median0.20.51.2-0.9-0.5-0.9-0.8-0.8-0.7-0.7-0.5-0.20.6-1.1-0.10.10.00.3-0.6-0.50.70.8-1.1-1.0-0.7
Reaction time mean minus median AUC0.41.13.2-1.2-0.8-1.2-1.2-1.2-1.0-1.0-0.8-0.20.9-1.8-0.20.1-0.10.5-0.8-0.70.91.1-1.7-1.5-1.0
Reaction time num false alarms0.30.41.3-0.8-0.6-0.6-0.5-0.5-0.5-0.8-0.5-0.10.9-0.2-0.3-0.0-0.00.4-0.5-0.50.60.7-1.2-1.1-0.7
Reaction time num false alarms AUC0.40.72.4-0.4-0.1-0.1-0.00.1-0.1-0.40.00.50.60.30.40.60.61.0-1.0-1.11.31.3-1.5-1.5-1.3
Reaction time trials correct on left0.71.32.11.21.11.21.21.11.41.41.31.3-1.30.91.21.11.31.5-1.3-1.00.90.7-0.2-0.4-0.8
Reaction time trials on left0.71.32.31.21.11.21.21.11.41.41.31.3-1.40.91.21.21.31.5-1.4-1.11.00.8-0.3-0.5-0.9
Reaction time mean1.42.35.2-1.7-1.8-2.0-2.1-2.1-2.0-1.8-2.0-1.22.1-2.3-1.5-1.2-1.4-1.00.40.7-0.3-0.1-0.8-0.60.1
Reaction time mean AUC1.32.14.9-1.7-1.7-2.0-2.0-2.1-2.0-1.8-1.8-1.31.9-2.2-1.4-1.1-1.3-1.00.40.5-0.3-0.0-0.9-0.70.0
Median of all reaction times2.33.36.7-1.9-2.2-2.3-2.4-2.5-2.3-2.1-2.4-1.62.6-2.5-2.0-1.8-1.9-1.60.91.2-0.8-0.6-0.6-0.20.5
Reaction time omissions0.30.41.4-0.5-0.1-0.3-0.20.0-0.3-0.20.20.1-0.4-0.20.40.60.61.1-0.8-1.00.80.9-1.2-1.2-1.1
Reaction time false alarm rate0.40.61.9-1.1-0.8-0.9-0.8-0.7-0.9-1.2-0.8-0.31.4-0.5-0.4-0.2-0.30.0-0.2-0.40.50.7-1.2-1.1-0.6
Reaction time premature initiation rate0.40.62.00.40.50.70.50.70.60.71.00.6-1.40.80.80.91.01.0-0.7-0.90.70.6-0.4-0.5-0.8
Reaction time premature initiations0.81.43.31.01.11.21.11.11.21.41.51.1-1.81.11.31.31.41.4-1.2-1.10.90.8-0.3-0.5-0.9
Std. dev. reaction times0.71.44.1-1.6-1.4-1.7-1.6-1.7-1.4-1.5-1.3-0.91.4-2.0-0.9-0.6-0.7-0.4-0.1-0.10.20.5-1.3-1.1-0.5
Reaction time trials completed0.71.32.31.21.11.21.21.11.41.41.31.3-1.40.91.21.21.31.5-1.4-1.11.00.8-0.3-0.5-0.9
Reaction time trials AUC0.61.12.01.00.91.11.11.01.21.31.21.2-1.30.81.11.11.21.4-1.3-0.90.90.7-0.3-0.4-0.8
Run reversals in cocaine runway, females0.40.40.80.20.30.50.40.20.30.00.40.4-0.30.30.60.70.70.7-0.6-0.80.80.9-0.8-0.8-0.8
Run reversals in cocaine runway, males0.40.41.1-0.6-0.10.00.10.3-0.1-0.10.30.1-0.50.80.40.50.60.8-1.0-0.80.60.7-1.0-1.0-1.0
Latency to leave start box in cocaine runway1.31.53.51.11.31.31.51.91.41.21.60.9-1.71.81.51.31.40.9-0.6-1.00.90.8-0.0-0.2-0.6
Latency to leave start box in cocaine runway, F0.91.02.00.30.60.50.61.10.50.41.00.6-1.11.11.11.21.31.2-1.0-1.41.21.3-1.0-1.2-1.3
Latency to leave start box in cocaine runway, M3.23.06.92.12.22.32.52.62.52.02.01.3-2.22.51.81.41.30.5-0.1-0.40.30.11.41.10.3
Std. dev. time between licks in bursts0.30.41.3-0.3-0.4-0.0-0.00.2-0.1-0.10.1-0.9-0.90.7-0.5-0.6-0.3-0.01.00.7-1.0-1.20.80.70.6
Total sessions with >9 infusions0.81.03.5-0.3-0.5-0.6-0.9-1.0-0.6-0.6-0.70.81.2-1.0-0.10.30.10.7-1.3-1.01.11.4-1.9-1.8-1.3
Short access day 1 total inactive lever presses0.30.52.01.00.60.50.3-0.10.70.5-0.11.40.9-0.60.20.40.20.5-0.8-0.70.71.0-0.7-0.7-0.4
Short access day 10 total inactive lever presses0.10.21.00.2-0.3-0.4-0.3-0.60.00.1-0.40.40.8-1.0-0.2-0.1-0.10.0-0.5-0.20.50.4-0.6-0.5-0.3
Short access day 1 total infusions0.20.20.90.40.20.0-0.1-0.20.30.1-0.00.70.5-0.60.20.40.30.4-0.5-0.70.51.0-0.9-0.8-0.6
Short access day 10 total infusions1.01.23.8-0.9-1.2-1.3-1.5-1.6-1.3-1.3-1.5-0.41.9-1.9-1.1-0.9-1.0-0.70.40.30.00.1-0.8-0.6-0.0
Short access total infusions0.70.92.6-0.7-0.9-1.0-1.3-1.3-0.9-0.9-1.00.11.5-1.6-0.7-0.3-0.4-0.1-0.3-0.40.50.8-1.4-1.2-0.7
Short access day 1 locomotion0.00.00.10.20.10.10.00.10.00.2-0.10.00.1-0.2-0.2-0.2-0.2-0.30.30.2-0.4-0.10.20.20.3
Short access day 10 total locomotion0.20.31.10.50.2-0.1-0.1-0.2-0.2-0.0-0.10.80.5-0.40.30.50.30.5-0.7-0.71.01.1-1.0-0.9-0.7
Short access total locomotion0.20.31.10.0-0.4-0.5-0.6-0.7-0.5-0.4-0.70.21.1-1.0-0.4-0.2-0.3-0.1-0.1-0.20.30.5-0.7-0.6-0.3
One hour access (0.3 mA shock)0.70.82.51.61.51.21.11.01.11.21.01.1-0.50.60.90.70.60.40.1-0.20.30.30.80.70.4
Compulsive drug intake1.31.52.71.41.51.51.31.01.21.41.21.6-1.00.91.41.41.21.5-1.5-1.11.11.2-0.3-0.4-0.7
One hour access (shock baseline)0.20.31.40.1-0.1-0.4-0.3-0.1-0.2-0.3-0.3-0.40.5-0.4-0.4-0.5-0.5-0.91.20.6-0.4-0.50.50.60.7
Social response proportion0.80.92.80.90.80.80.70.80.70.80.4-0.1-0.20.9-0.2-0.5-0.4-0.71.20.9-1.4-1.01.71.61.5
Social responses0.00.00.10.30.20.20.10.20.20.40.20.0-0.20.10.1-0.00.00.10.10.1-0.3-0.10.30.30.2
Social time0.50.61.40.70.90.60.70.70.70.60.61.1-0.20.40.90.90.80.9-0.9-1.00.91.2-0.7-0.7-0.7
Soleus weight9.628.352.36.16.66.86.97.16.46.67.04.9-7.17.25.95.15.53.9-2.0-3.32.22.01.80.9-1.3
Bone: stiffness1.21.92.81.41.51.41.31.51.41.41.41.6-0.81.31.51.51.51.4-1.3-1.71.41.7-0.9-1.1-1.2
Tibialis anterior weight9.933.755.17.07.17.47.37.37.17.27.36.2-7.16.86.55.96.14.8-3.4-4.33.13.10.9-0.1-2.2
Time to tail flick, vehicle, before self-admin1.31.35.1-2.3-1.7-1.6-1.4-1.1-1.6-1.7-1.0-1.90.2-0.5-1.1-1.0-0.8-0.60.60.7-0.7-0.9-0.2-0.10.1
Time to tail flick, vehicle, after self-admin0.00.10.20.40.20.30.30.40.30.1-0.10.30.4-0.2-0.0-0.0-0.1-0.20.10.1-0.10.00.20.20.2
Time to tail flick, test, before self-admin3.63.76.3-1.6-1.7-1.4-1.2-1.2-1.2-1.5-1.7-2.31.5-1.2-2.2-2.3-2.2-2.42.52.4-2.4-2.51.71.82.1
Time to tail flick, test, after self-admin1.31.43.2-1.2-1.5-1.7-1.6-1.8-1.5-1.4-1.5-1.01.6-1.5-1.2-1.0-1.1-0.80.40.5-0.1-0.1-0.7-0.50.1
Delta time to tail flick, vehicle, before/after SA0.30.31.51.20.70.60.60.50.80.60.11.00.5-0.30.30.30.1-0.1-0.1-0.20.30.50.00.00.1
Delta time to tail flick, test, before/after SA1.01.02.51.31.00.50.50.20.70.80.61.4-0.30.11.11.21.01.0-1.3-1.21.51.6-1.0-1.0-1.0
Tibia length0.51.44.51.30.90.90.70.60.70.90.1-0.30.10.2-0.2-0.6-0.7-1.71.71.3-1.5-1.32.12.11.9
Ambulatory time before self-admin0.10.20.5-0.5-0.4-0.5-0.5-0.2-0.5-0.7-0.5-0.40.6-0.1-0.3-0.2-0.20.00.1-0.10.00.3-0.5-0.5-0.2
Ambulatory time after self-admin1.82.14.01.91.91.81.51.41.51.51.42.0-0.71.11.61.61.51.6-1.3-1.51.11.6-0.5-0.6-0.9
Bone: tissue strength0.50.51.6-0.6-0.7-0.8-0.9-1.0-0.8-0.7-1.0-0.51.3-0.8-0.8-0.8-0.9-0.50.30.6-0.5-0.3-0.10.10.4
Total heroin consumption0.60.71.90.30.70.90.91.00.30.61.10.5-1.21.40.90.91.11.1-0.9-1.00.50.7-0.4-0.6-0.8
Bone: trabecular number0.91.52.7-1.5-1.6-1.4-1.5-1.4-1.4-1.4-1.4-1.31.4-1.0-1.5-1.4-1.3-1.20.90.9-0.9-0.9-0.10.00.4
Bone: trabecular spacing0.00.00.10.00.30.10.10.10.10.00.20.1-0.2-0.10.40.40.20.1-0.2-0.20.30.3-0.1-0.1-0.2
Bone: trabecular thickness0.20.20.91.00.60.60.50.20.70.70.11.00.50.00.10.1-0.0-0.2-0.00.00.20.20.30.30.3
Bone: trabecular tissue density6.08.917.64.24.13.94.03.73.93.93.53.6-2.92.93.22.82.82.1-1.6-2.01.41.80.70.3-0.5
Water consumed over 24 hours0.10.10.4-0.0-0.2-0.2-0.2-0.4-0.2-0.3-0.5-0.20.6-0.4-0.3-0.3-0.5-0.60.50.5-0.2-0.20.30.30.4
Number of responses in last shaping day0.00.10.30.60.20.30.1-0.10.20.40.00.50.2-0.00.00.10.10.2-0.4-0.00.20.00.00.0-0.0