Hub : Genes

Rhobtb2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Rhobtb2 0.4 0.27 0.0e+00 0.31 0.31 0.31 0.3 4.4e-29 2.8e-29 6.1e-29 8.8e-29
2 pVTA gene expression Rhobtb2 0.07 0.08 7.2e-03 0.08 0.04 0.07 0.07 3.6e-04 8.4e-03 7.7e-04 5.6e-04
3 OFC gene expression Rhobtb2 0.18 0.17 6.2e-03 0.05 0.05 0.05 0.04 2.7e-02 2.1e-02 2.4e-02 4.4e-02
4 BLA gene expression Rhobtb2 0.14 0.12 2.7e-05 0.06 0.07 0.05 0.07 5.2e-04 1.3e-04 1.2e-03 1.5e-04
5 RMTg alternative polyA XM_017599699.2 0.11 0.11 1.0e-02 0 -0 -0 0.06 3.2e-01 4.3e-01 3.8e-01 8.5e-03
6 Adipose gene expression Rhobtb2 0.51 0.26 0.0e+00 0.35 0.35 0.35 0.35 1.6e-40 3.3e-40 1.7e-40 8.2e-41
7 Liver gene expression Rhobtb2 0.05 0.05 6.7e-06 0.05 0.05 0.04 0.05 6.7e-06 6.9e-06 4.9e-05 7.3e-06
8 NAcc gene expression Rhobtb2 0.12 0.11 1.3e-10 0.09 0.09 0.09 0.09 1.3e-10 2.8e-10 4.4e-10 3.5e-10
9 PL gene expression Rhobtb2 0.27 0.18 0.0e+00 0.24 0.23 0.23 0.23 6.3e-26 3.5e-25 1.0e-24 1.6e-24
10 IL gene expression Rhobtb2 0.29 0.22 1.4e-04 0.12 0.12 0.1 0.1 6.9e-04 7.0e-04 2.5e-03 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.52.63.1-1.61.8-1.6-1.61.7-1.71.71.51.51.5
Area under the delay curve0.00.00.10.2-0.30.20.2-0.20.2-0.2-0.2-0.2-0.2
BMI with tail0.41.31.51.2-1.11.21.2-1.11.1-1.1-1.2-1.2-0.9
BMI without tail0.81.71.8-1.31.3-1.2-1.21.3-1.31.31.31.31.3
Body weight0.41.82.01.4-1.31.31.3-1.31.3-1.3-1.4-1.4-1.4
Weight adjusted by age1.82.12.21.5-1.41.41.4-1.51.5-1.5-1.4-1.4-1.4
Bone surface0.61.11.4-1.01.2-1.0-1.01.1-1.11.11.01.00.9
Bone volume0.81.31.7-1.21.3-1.1-1.11.2-1.21.21.11.11.1
Breakpoint value in progressive ratio session0.00.00.10.2-0.10.20.2-0.20.2-0.2-0.2-0.2-0.2
Number of licking bursts0.00.00.00.1-0.10.10.1-0.10.1-0.1-0.1-0.1-0.2
Context. condit. distance diff. score0.91.01.1-1.01.0-1.0-1.01.0-1.01.01.01.01.0
Locomotion velocity, session 10.10.20.20.4-0.30.40.4-0.40.4-0.4-0.4-0.4-0.4
Locomotion distance, session 10.00.00.0-0.10.0-0.1-0.10.0-0.00.00.20.20.2
Locomotion velocity, session 20.10.10.2-0.20.4-0.2-0.20.3-0.30.30.20.20.1
Locomotion distance, session 20.00.00.0-0.20.2-0.2-0.20.2-0.20.20.20.20.1
Locomotion velocity, session 30.50.60.60.8-0.80.70.7-0.80.8-0.8-0.7-0.7-0.7
Locomotion distance, session 30.00.00.0-0.1-0.0-0.1-0.10.1-0.10.10.20.20.2
Stereotopy head waving bouts, day 30.70.80.90.9-0.90.90.9-1.01.0-1.0-0.8-0.8-0.9
Stereotopy head waving duration, day 32.73.23.41.8-1.81.81.8-1.81.8-1.8-1.7-1.7-1.8
Locomotion velocity, session 74.65.05.6-2.32.4-2.2-2.22.2-2.22.22.32.32.3
Locomotion distance, session 73.54.54.7-2.12.2-2.1-2.12.1-2.12.12.12.12.1
Stereotopy head waving bouts, day 71.71.92.01.4-1.31.41.4-1.41.4-1.4-1.4-1.4-1.3
Stereotopy head waving duration, day 72.42.93.11.8-1.61.71.7-1.71.7-1.7-1.8-1.8-1.7
Locomotion velocity, session 80.00.00.0-0.10.2-0.1-0.10.1-0.10.10.10.10.1
Locomotion distance, session 80.60.91.0-1.00.9-1.0-1.01.0-1.01.01.01.00.9
Degree of sensitization distance4.94.95.6-2.32.4-2.2-2.22.2-2.22.22.22.22.2
Degree of sensitization stereotypy1.11.21.31.1-1.01.11.1-1.11.1-1.1-1.2-1.2-1.1
Conditioned locomotion0.00.00.1-0.20.1-0.2-0.20.2-0.20.20.20.20.2
Cocaine response after cond. corrected0.30.30.30.6-0.50.50.5-0.50.5-0.5-0.5-0.5-0.6
Cocaine response after cond. not corrected0.20.20.20.4-0.40.40.4-0.40.4-0.4-0.4-0.4-0.4
Cocaine response before conditioning0.10.20.3-0.40.5-0.4-0.40.4-0.40.40.40.40.5
Saline control response0.20.30.3-0.50.5-0.5-0.50.5-0.50.50.50.50.5
Bone: connectivity density3.04.65.4-2.22.3-2.1-2.12.2-2.22.22.12.12.0
Bone: cortical apparent density0.00.00.1-0.20.1-0.2-0.20.2-0.20.20.20.20.3
Bone: cortical area0.00.00.0-0.10.2-0.1-0.10.1-0.10.10.10.10.1
Bone: cortical porosity1.41.51.61.3-1.21.21.2-1.21.2-1.2-1.3-1.3-1.2
Bone: cortical porosity0.60.60.70.8-0.70.80.8-0.80.8-0.8-0.8-0.8-0.8
Bone: cortical thickness0.00.00.1-0.20.2-0.2-0.20.2-0.20.20.20.20.3
Bone: cortical thickness0.00.00.1-0.20.2-0.2-0.20.2-0.20.20.20.20.3
Bone: cortical tissue density0.00.00.1-0.20.1-0.2-0.20.2-0.20.20.20.20.3
Condit. Reinf. active minus inactive responses0.50.60.90.8-0.90.70.7-0.80.8-0.8-0.6-0.6-0.8
Condit. Reinf. active-inactive response ratio2.42.63.31.6-1.81.61.6-1.71.7-1.7-1.5-1.5-1.4
Condit. Reinf. active responses0.00.00.00.0-0.20.00.0-0.10.1-0.10.00.0-0.2
Condit. Reinf. inactive responses2.93.53.6-1.91.9-1.9-1.91.9-1.91.91.81.81.8
Incentive salience index mean0.81.01.31.0-1.20.90.9-1.11.1-1.1-0.9-0.9-1.0
Condit. Reinf. lever presses0.30.40.50.6-0.70.60.6-0.60.6-0.6-0.5-0.5-0.6
Condit. Reinf. active minus inactive responses0.30.40.5-0.60.6-0.6-0.60.7-0.70.70.60.60.7
Condit. Reinf. active-inactive response ratio0.10.10.20.4-0.30.40.4-0.30.3-0.3-0.4-0.4-0.3
Condit. Reinf. active responses0.91.31.4-1.11.0-1.1-1.11.2-1.21.21.11.11.2
Condit. Reinf. inactive responses2.32.93.0-1.71.6-1.7-1.71.7-1.71.71.71.71.7
Condit. Reinf. lever presses0.10.10.1-0.30.3-0.3-0.30.3-0.30.30.30.30.3
Condit. Reinf. lever reinforcers received0.60.80.9-0.90.8-0.9-0.91.0-1.01.00.90.90.9
Conditioned reinforcement - actives2.72.72.9-1.71.6-1.6-1.61.6-1.61.61.71.71.6
Conditioned reinforcement - inactives3.03.43.8-1.91.9-1.8-1.91.8-1.81.81.81.81.8
Conditioned locomotion1.11.31.5-1.11.2-1.1-1.11.2-1.21.21.11.11.1
Patch foraging indifference point 0 sec2.03.33.6-1.91.8-1.9-1.91.9-1.91.91.81.81.5
Patch foraging indifference point AUC0.60.70.80.8-0.90.80.8-0.90.9-0.9-0.7-0.7-0.7
Delay disc. indifference point, 0s delay0.30.30.5-0.60.5-0.6-0.60.5-0.50.50.70.70.6
Delay disc. indifference point, 16s delay0.20.20.2-0.50.4-0.5-0.50.4-0.40.40.40.40.5
Delay disc. indifference point, 2s delay1.51.61.71.3-1.31.31.3-1.31.3-1.3-1.3-1.3-1.3
Delay disc. indifference point, 24s delay0.30.30.30.5-0.50.50.5-0.50.5-0.5-0.5-0.5-0.5
Delay disc. indifference point, 4s delay1.61.71.81.3-1.41.31.3-1.31.3-1.3-1.2-1.2-1.3
Delay disc. indifference point, 8s delay0.00.00.0-0.10.1-0.1-0.10.1-0.10.10.20.20.1
Indifference point function ln k0.00.00.0-0.10.2-0.1-0.10.2-0.20.20.10.10.2
Indifference point function log k0.00.00.0-0.10.2-0.1-0.10.2-0.20.20.10.10.2
Patch foraging total patch changes 0 sec1.72.73.0-1.71.6-1.7-1.71.6-1.61.61.61.61.4
Patch foraging total patch changes 12 sec0.70.91.1-1.00.8-1.0-1.00.9-0.90.91.01.00.7
Patch foraging total patch changes 18 sec1.82.32.6-1.61.4-1.6-1.61.5-1.51.51.61.61.3
Patch foraging total patch changes 24 sec0.00.00.0-0.1-0.1-0.1-0.1-0.10.1-0.10.00.00.2
Patch foraging total patch changes 6 sec0.30.40.5-0.70.6-0.7-0.70.6-0.60.60.70.70.3
Patch foraging time to switch 0 sec0.71.01.2-1.11.1-1.1-1.10.9-0.90.91.01.00.8
Patch foraging water rate 0 sec0.30.50.60.8-0.70.70.7-0.60.6-0.6-0.8-0.8-0.7
Patch foraging water rate 12 sec0.50.71.01.0-0.71.01.0-0.80.8-0.8-1.0-1.0-0.8
Patch foraging water rate 18 sec2.73.64.22.0-1.82.02.0-1.81.8-1.8-2.0-2.0-1.7
Patch foraging water rate 24 sec0.00.10.10.3-0.00.30.3-0.10.1-0.1-0.4-0.4-0.2
Patch foraging water rate 6 sec1.92.83.21.8-1.71.81.8-1.61.6-1.6-1.7-1.7-1.5
Seeking ratio, delayed vs. immediate footshock1.21.31.6-1.11.2-1.1-1.11.3-1.31.31.01.01.1
Distance traveled before self-admin1.01.01.11.0-0.91.01.0-1.01.0-1.0-1.1-1.1-1.0
Distance traveled after self-admin2.12.32.61.6-1.51.61.6-1.41.4-1.4-1.6-1.6-1.6
Extensor digitorum longus weight12.850.253.17.3-7.07.17.1-7.07.0-7.0-7.1-7.1-7.2
Bone: elastic displacement0.60.60.9-0.80.7-0.8-0.80.7-0.70.70.80.81.0
Bone: elastic work0.30.40.6-0.60.5-0.6-0.60.6-0.60.60.60.60.8
Bone: endosteal estimation0.10.20.40.5-0.30.50.5-0.40.4-0.4-0.5-0.5-0.6
Bone: endosteal perimeter0.10.10.20.4-0.20.40.4-0.30.3-0.3-0.4-0.4-0.5
Epididymis fat weight2.14.95.3-2.32.3-2.3-2.32.2-2.22.22.32.31.7
Delta time in closed arm before/after self-admin2.12.12.4-1.51.4-1.4-1.41.4-1.41.41.51.51.4
Delta time in open arm before/after self-admin0.10.10.2-0.20.2-0.2-0.20.4-0.40.40.00.00.2
Diff in mean of infusions in LGA sessions2.93.24.21.7-1.51.71.7-2.02.0-2.0-1.7-1.7-1.7
Delay discount exponential model param0.20.20.3-0.50.6-0.5-0.50.5-0.50.50.50.50.5
Extinction: sum of active levers before priming2.62.62.8-1.71.5-1.6-1.61.6-1.61.61.71.71.6
Active lever presses in extinction session 60.30.20.3-0.60.6-0.6-0.60.2-0.20.20.60.60.6
Bone: final force0.10.20.20.4-0.40.40.4-0.40.4-0.4-0.4-0.4-0.3
Bone: final moment0.10.10.10.4-0.30.40.4-0.40.4-0.4-0.4-0.4-0.3
Food consumed during 24 hour testing period0.30.30.4-0.50.5-0.5-0.50.7-0.70.70.50.50.4
Glucose0.00.00.0-0.10.1-0.1-0.10.1-0.10.10.20.20.1
Heart weight0.00.00.1-0.10.3-0.1-0.10.1-0.10.10.00.0-0.2
Delay discount hyperbolic model param0.60.60.7-0.80.8-0.8-0.80.8-0.80.80.70.70.7
Intermittent access intake day 1-15 change2.32.32.6-1.51.5-1.4-1.41.6-1.61.61.41.41.4
Intermittent access intake escalation1.51.51.8-1.21.2-1.2-1.21.3-1.31.31.11.11.1
Intermittent access intake escalation 20.50.50.7-0.60.7-0.6-0.60.8-0.80.80.60.60.6
Intermitt. access day 1 inactive lever presses0.10.10.1-0.30.3-0.3-0.30.3-0.30.30.30.30.3
Intermitt. access day 15 inactive lever presses0.00.00.1-0.10.2-0.1-0.1-0.20.2-0.20.10.10.1
Intermitt. access escalation Index0.50.50.60.7-0.70.60.6-0.80.8-0.8-0.6-0.6-0.6
Intermittent access day 1 total infusions0.00.00.1-0.20.3-0.2-0.20.1-0.10.10.20.20.2
Intermittent access day 15 total infusions1.01.11.4-1.11.2-1.0-1.11.1-1.11.11.01.01.0
Intermittent access terminal intake (last 3 days)0.20.30.4-0.50.6-0.5-0.50.6-0.60.60.40.40.5
Intermittent access total infusions0.40.50.7-0.70.8-0.7-0.70.7-0.70.70.70.70.7
Intermittent access day 1 locomotion0.30.40.5-0.60.7-0.6-0.60.6-0.60.60.60.60.6
Intermittent access day 15 total locomotion1.61.72.1-1.31.2-1.3-1.31.5-1.51.51.31.31.2
Intermittent access total locomotion0.50.60.7-0.80.8-0.7-0.70.8-0.80.80.70.70.7
Intermittent access standard deviation1.41.41.7-1.21.2-1.1-1.11.3-1.31.31.11.11.1
Left kidney weight0.30.71.10.9-0.70.90.8-0.60.6-0.6-1.1-1.1-1.0
Right kidney weight0.10.40.6-0.60.7-0.6-0.60.7-0.70.70.40.4-0.2
Cocaine induced anxiety0.10.20.20.4-0.40.40.4-0.50.5-0.5-0.4-0.4-0.4
Post-drug Anxiety0.50.50.6-0.70.7-0.7-0.70.7-0.70.70.70.70.7
Baseline Anxiety0.90.91.0-0.90.9-0.9-0.91.0-1.01.00.90.90.9
Tail length0.92.73.0-1.71.7-1.6-1.61.7-1.71.71.71.71.3
Length with tail0.10.30.90.5-0.50.50.5-0.50.5-0.5-0.6-0.6-0.9
Length without tail4.08.79.33.0-2.92.92.9-2.92.9-2.9-3.1-3.1-3.0
Times rat made contact with spout0.50.50.7-0.70.9-0.7-0.70.7-0.70.70.70.70.7
Lifetime Intake0.40.50.7-0.70.8-0.7-0.70.6-0.60.60.70.70.7
Liver weight, left2.33.63.82.0-1.91.91.9-1.91.9-1.9-1.9-1.9-2.0
Liver weight, right0.71.21.41.1-1.11.11.1-1.11.1-1.1-1.1-1.1-1.2
Locomotor activity1.42.22.51.5-1.51.51.5-1.51.5-1.5-1.6-1.6-1.2
Locomotor testing distance0.00.00.2-0.10.1-0.0-0.00.1-0.10.10.00.00.5
Locomotor testing rearing0.20.40.5-0.60.7-0.6-0.60.7-0.70.70.60.60.5
Locomotion in novel chamber0.10.20.2-0.40.4-0.4-0.40.4-0.40.40.40.40.4
Locomotion in novel chamber post-restriction0.60.70.80.9-0.80.90.9-0.80.8-0.8-0.8-0.8-0.9
Fecal boli incidents, locomotor time 10.80.91.01.0-1.01.01.0-0.90.9-0.9-0.9-0.9-0.9
Change in fecal boli incidents, locomotor task0.10.10.20.3-0.20.30.3-0.40.4-0.4-0.3-0.3-0.3
Time >=10cm from walls, locomotor time 10.70.70.9-0.90.8-0.9-0.90.7-0.70.71.01.00.9
Bouts of movement, locomotor time 15.05.45.82.4-2.32.32.4-2.42.4-2.4-2.2-2.2-2.3
Total resting periods, locomotor time 14.95.45.82.4-2.32.32.4-2.42.4-2.4-2.2-2.2-2.3
Rest time, locomotor task time 13.23.63.81.9-1.91.91.9-2.02.0-2.0-1.8-1.8-1.8
Distance moved, locomotor task time 13.13.43.7-1.91.8-1.8-1.81.9-1.91.91.71.71.8
Vertical activity count, locomotor time 11.11.11.3-1.11.1-1.1-1.11.1-1.11.10.90.91.1
Time >=10cm from walls, locomotor time 20.40.40.50.6-0.60.60.6-0.60.6-0.6-0.7-0.7-0.6
Bouts of movement, locomotor time 23.63.94.22.1-1.82.02.0-2.02.0-2.0-1.9-1.9-2.0
Total resting periods, locomotor time 24.24.54.82.2-2.02.12.1-2.12.1-2.1-2.1-2.1-2.1
Rest time, locomotor task time 21.01.21.41.1-1.01.01.0-1.11.1-1.1-1.2-1.2-1.0
Distance moved, locomotor task time 22.83.33.7-1.81.7-1.8-1.81.9-1.91.91.71.71.7
Vertical activity count, locomotor time 20.30.40.4-0.60.5-0.6-0.60.6-0.60.60.60.60.6
Light reinforcement 13.46.27.3-2.62.6-2.5-2.52.4-2.42.42.52.52.7
Light reinforcement 21.21.62.0-1.41.4-1.3-1.41.1-1.11.11.31.31.0
Bone: marrow area0.10.10.20.4-0.20.40.4-0.30.3-0.3-0.4-0.4-0.5
Bone: maximum diameter0.30.60.70.8-0.60.80.8-0.70.7-0.7-0.8-0.8-0.8
Bone: maximum force0.20.40.40.6-0.50.60.6-0.60.6-0.6-0.6-0.6-0.6
Bone: maximum moment0.10.20.20.5-0.30.50.5-0.40.4-0.4-0.4-0.4-0.4
Mean time between licks in bursts2.02.83.0-1.71.6-1.7-1.71.6-1.61.61.71.71.7
Mean num. licks in bursts0.40.50.6-0.70.7-0.7-0.70.6-0.60.60.70.70.7
Cd content in liver0.30.30.4-0.60.6-0.6-0.60.4-0.40.40.60.60.6
Co content in liver3.94.54.82.2-2.22.12.1-2.12.1-2.1-2.1-2.1-2.0
Cu content in liver0.60.70.80.8-0.80.80.8-0.90.9-0.9-0.8-0.8-0.8
Fe content in liver2.12.52.7-1.61.6-1.6-1.61.6-1.61.61.61.61.5
K content in liver0.60.60.6-0.80.8-0.8-0.80.7-0.70.70.80.80.7
Mg content in liver1.21.21.4-1.21.1-1.1-1.11.0-1.01.01.11.11.1
Mn content in liver2.12.32.5-1.61.5-1.5-1.51.5-1.51.51.51.51.5
Na content in liver0.70.70.90.9-0.80.80.8-0.90.9-0.9-0.8-0.8-0.9
Rb content in liver0.30.30.4-0.60.6-0.6-0.60.6-0.60.60.50.50.4
Se content in liver0.91.11.2-1.11.1-1.0-1.11.0-1.01.01.01.01.1
Sr content in liver0.40.40.5-0.70.6-0.7-0.60.6-0.60.60.70.70.7
Zn content in liver1.01.11.31.1-1.01.01.0-1.11.1-1.1-1.0-1.0-1.0
Bone: minimum diameter0.10.20.30.5-0.20.50.5-0.40.4-0.4-0.5-0.5-0.5
Time in familiar zone, hab. session 10.00.00.10.1-0.20.10.1-0.10.1-0.1-0.2-0.2-0.2
Time in novel zone, hab. session 11.31.31.41.2-1.11.11.1-1.21.2-1.2-1.1-1.1-1.0
Total zone transitions, hab. session 10.20.30.40.5-0.70.50.5-0.60.6-0.6-0.5-0.5-0.5
Total locomotion distance, hab. session 10.00.00.0-0.0-0.1-0.0-0.0-0.00.0-0.00.10.10.0
Locomotion velocity, hab. session 10.10.10.2-0.40.2-0.4-0.30.3-0.30.30.40.40.4
Time in familiar zone, hab. session 22.12.12.41.5-1.51.41.4-1.41.4-1.4-1.4-1.4-1.6
Time in novel zone, hab. session 20.80.80.9-0.90.9-0.9-0.90.9-0.90.90.90.91.0
Total zone transitions, hab. session 21.51.92.01.4-1.41.41.4-1.41.4-1.4-1.3-1.3-1.3
Total locomotion distance, hab. session 20.30.30.40.6-0.70.50.6-0.60.6-0.6-0.5-0.5-0.6
Locomotion velocity, hab. session 20.60.80.90.9-1.00.90.9-0.90.9-0.9-0.8-0.8-0.9
Novel to familiar place preference ratio1.61.61.8-1.31.3-1.3-1.31.3-1.31.31.31.31.3
Novelty place preference1.21.31.4-1.11.1-1.1-1.11.1-1.11.11.11.11.2
Time in novel zone, NPP test0.60.60.7-0.80.8-0.8-0.80.8-0.80.80.80.80.8
Total zone transitions, NPP test0.10.20.3-0.50.4-0.5-0.50.4-0.40.40.50.50.4
Total locomotion distance, NPP test2.53.53.8-1.91.8-1.9-1.91.8-1.81.81.91.91.7
Locomotion velocity, NPP test2.43.53.7-1.91.8-1.9-1.91.8-1.81.81.91.91.7
Intraocular pressure0.50.71.5-0.90.7-0.9-0.90.7-0.70.70.90.91.2
Delta distance traveled before/after self-admin2.42.62.81.7-1.71.61.6-1.51.5-1.5-1.6-1.6-1.6
Delta ambulatory time before/after self-admin2.22.42.81.6-1.71.61.6-1.51.5-1.5-1.6-1.6-1.5
Parametrial fat weight3.46.77.4-2.72.7-2.6-2.62.6-2.62.62.62.62.0
Pavlov. Cond. lever latency0.00.00.00.00.00.00.0-0.00.0-0.0-0.0-0.00.1
Pavlov. Cond. magazine entry latency0.00.00.1-0.20.1-0.2-0.20.2-0.20.20.20.20.3
Pavlov. Cond. change in total contacts1.01.11.11.1-1.01.01.0-1.01.0-1.0-1.0-1.0-1.0
Pavlov. Cond. index score0.10.10.10.3-0.30.20.2-0.30.3-0.3-0.3-0.3-0.2
Pavlov. Cond. latency score0.00.00.00.1-0.20.10.1-0.10.1-0.1-0.1-0.1-0.1
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.0-0.1-0.10.1-0.10.10.10.1-0.0
Pavlov. Cond. magazine entry number0.40.50.7-0.70.8-0.7-0.70.7-0.70.70.70.70.7
Pavlov. Cond. intertrial magazine entries0.10.10.1-0.30.3-0.3-0.30.3-0.30.30.30.30.2
Pavlov. Cond. lever-magazine prob. diff.0.10.20.20.4-0.50.40.4-0.40.4-0.4-0.4-0.4-0.4
Pavlov. Cond. response bias0.10.20.20.4-0.40.40.4-0.40.4-0.4-0.4-0.4-0.4
Pavlov. Cond. lever latency0.30.50.5-0.70.7-0.7-0.70.6-0.60.60.70.70.7
Pavlov. Cond. magazine entry latency0.10.10.1-0.30.2-0.3-0.30.3-0.30.30.30.30.3
Pavlov. Cond. change in total contacts1.62.22.41.5-1.51.51.5-1.51.5-1.5-1.5-1.5-1.5
Pavlov. Cond. index score0.50.60.70.8-0.80.80.8-0.80.8-0.8-0.8-0.8-0.8
Pavlov. Cond. latency score0.30.40.40.6-0.70.60.6-0.60.6-0.6-0.6-0.6-0.6
Pavlov. Cond. lever contacts0.40.50.50.7-0.70.70.7-0.70.7-0.7-0.7-0.7-0.7
Pavlov. Cond. magazine entry number0.00.10.10.2-0.20.20.2-0.30.3-0.3-0.2-0.2-0.2
Pavlov. Cond. intertrial magazine entries6.18.08.4-2.92.8-2.8-2.82.9-2.92.92.82.82.8
Pavlov. Cond. lever-magazine prob. diff.0.60.80.80.9-0.90.90.9-0.80.8-0.8-0.9-0.9-0.9
Pavlov. Cond. response bias0.40.60.70.8-0.80.80.8-0.70.7-0.7-0.8-0.8-0.8
Time in closed arm before self-admin1.92.12.41.5-1.51.51.5-1.41.4-1.4-1.6-1.6-1.4
Time in closed arm after self-admin0.60.60.70.8-0.80.80.8-0.80.8-0.8-0.8-0.8-0.8
Time in open arm before self-admin0.20.20.40.4-0.30.30.3-0.60.6-0.6-0.2-0.2-0.3
Time in open arm after self-admin0.10.10.1-0.30.2-0.3-0.30.3-0.30.30.30.30.3
Bone: periosteal estimation0.00.10.10.3-0.00.30.2-0.20.2-0.2-0.3-0.3-0.3
Bone: periosteal perimeter0.00.00.00.10.10.10.1-0.00.0-0.0-0.1-0.1-0.1
Bone: post-yield work0.20.20.4-0.50.7-0.5-0.50.5-0.50.50.40.40.3
Progressive ratio test 1 active lever presses0.20.20.30.5-0.40.40.4-0.60.6-0.6-0.5-0.5-0.4
Progressive ratio test 1 breakpoint0.10.10.20.3-0.20.30.3-0.40.4-0.4-0.3-0.3-0.3
Progressive ratio test 1 inactive lever presses1.41.61.9-1.41.4-1.3-1.31.1-1.11.11.31.31.3
Progressive ratio test 2 active lever presses0.20.20.2-0.50.4-0.5-0.50.5-0.50.50.50.50.4
Progressive ratio test 2 breakpoint0.20.30.3-0.50.5-0.5-0.50.5-0.50.50.50.50.5
Progressive ratio test 2 inactive lever presses0.40.40.5-0.70.7-0.7-0.70.6-0.60.60.70.70.7
Incentive Sensitization - Responses1.01.11.2-1.01.0-1.0-1.01.1-1.11.11.01.01.0
Incentive Sensitization - Breakpoint1.41.51.7-1.21.1-1.2-1.21.3-1.31.31.21.21.2
Sum of active levers in priming session hrs 5-60.10.10.1-0.20.3-0.2-0.20.1-0.10.10.40.40.2
Progressive ratio0.10.10.1-0.40.4-0.3-0.30.3-0.30.30.20.20.3
Food seeking constrained by brief footshock1.41.71.81.3-1.31.31.3-1.31.3-1.3-1.3-1.3-1.3
Seeking ratio, punishment vs. effort0.91.01.21.1-1.11.11.1-1.01.0-1.0-1.0-1.0-1.0
Retroperitoneal fat weight0.20.61.0-0.80.9-0.8-0.81.0-1.01.00.60.60.1
Reaction time number correct0.50.70.90.9-0.90.90.9-0.70.7-0.7-1.0-1.0-0.8
Reaction time mean minus median0.20.30.40.5-0.60.40.4-0.50.5-0.5-0.5-0.5-0.4
Reaction time mean minus median AUC0.10.20.30.4-0.50.40.4-0.50.5-0.5-0.4-0.4-0.3
Reaction time num false alarms0.00.00.10.2-0.10.20.20.1-0.10.1-0.4-0.4-0.1
Reaction time num false alarms AUC0.00.00.10.00.10.0-0.00.2-0.20.2-0.2-0.20.1
Reaction time trials correct on left0.50.70.90.9-0.90.90.9-0.70.7-0.7-1.0-1.0-0.8
Reaction time trials on left0.40.50.70.8-0.80.80.8-0.60.6-0.6-0.8-0.8-0.6
Reaction time mean0.20.30.40.5-0.50.50.5-0.70.7-0.7-0.4-0.4-0.4
Reaction time mean AUC0.40.50.70.7-0.70.70.7-0.80.8-0.8-0.6-0.6-0.5
Median of all reaction times0.10.10.20.3-0.20.30.3-0.40.4-0.4-0.3-0.3-0.4
Reaction time omissions2.02.83.9-1.81.6-1.7-1.71.4-1.41.41.71.72.0
Reaction time false alarm rate0.20.20.3-0.40.5-0.4-0.40.5-0.50.50.30.30.5
Reaction time premature initiation rate1.41.92.21.4-1.41.41.4-1.51.5-1.5-1.3-1.3-1.1
Reaction time premature initiations2.12.93.11.8-1.81.71.7-1.71.7-1.7-1.7-1.7-1.4
Std. dev. reaction times0.20.30.40.5-0.70.50.5-0.70.7-0.7-0.5-0.5-0.2
Reaction time trials completed0.40.50.70.8-0.80.80.8-0.60.6-0.6-0.8-0.8-0.6
Reaction time trials AUC0.30.50.70.8-0.70.80.7-0.50.5-0.5-0.8-0.8-0.6
Run reversals in cocaine runway, females3.93.84.1-2.02.0-2.0-2.02.0-2.02.01.81.81.9
Run reversals in cocaine runway, males2.52.42.51.6-1.51.51.5-1.51.5-1.5-1.5-1.5-1.5
Latency to leave start box in cocaine runway0.50.60.60.8-0.60.80.8-0.80.8-0.8-0.7-0.7-0.8
Latency to leave start box in cocaine runway, F1.31.51.61.3-1.11.21.2-1.21.2-1.2-1.2-1.2-1.2
Latency to leave start box in cocaine runway, M1.31.21.3-1.11.1-1.1-1.11.1-1.11.11.11.11.1
Std. dev. time between licks in bursts1.41.71.9-1.31.4-1.3-1.31.2-1.21.21.31.31.3
Total sessions with >9 infusions0.00.00.0-0.10.2-0.1-0.10.0-0.00.00.10.10.1
Short access day 1 total inactive lever presses0.50.50.7-0.80.8-0.8-0.80.7-0.70.70.80.80.7
Short access day 10 total inactive lever presses0.30.40.5-0.70.7-0.6-0.60.5-0.50.50.60.60.6
Short access day 1 total infusions0.10.10.20.3-0.20.30.3-0.40.4-0.4-0.3-0.3-0.3
Short access day 10 total infusions0.00.00.0-0.20.2-0.2-0.20.0-0.00.00.20.20.2
Short access total infusions0.20.20.3-0.50.6-0.5-0.50.3-0.30.30.50.50.5
Short access day 1 locomotion0.20.20.20.5-0.30.40.4-0.40.4-0.4-0.5-0.5-0.4
Short access day 10 total locomotion0.50.60.7-0.80.8-0.8-0.80.7-0.70.70.80.80.8
Short access total locomotion0.70.71.0-0.91.0-0.9-0.90.8-0.80.80.90.90.9
One hour access (0.3 mA shock)0.30.40.5-0.60.6-0.6-0.60.7-0.70.70.50.50.5
Compulsive drug intake0.00.00.00.1-0.20.10.10.1-0.10.1-0.1-0.1-0.1
One hour access (shock baseline)0.00.00.0-0.00.1-0.0-0.0-0.10.1-0.1-0.0-0.00.0
Social response proportion0.10.10.20.3-0.20.30.3-0.20.2-0.2-0.4-0.4-0.4
Social responses1.11.41.5-1.21.1-1.2-1.21.2-1.21.21.21.21.1
Social time0.40.50.7-0.70.7-0.7-0.70.8-0.80.80.60.60.7
Soleus weight1.02.83.51.7-1.81.71.7-1.51.5-1.5-1.7-1.7-1.9
Bone: stiffness0.60.91.01.0-0.80.90.9-0.90.9-0.9-1.0-1.0-1.0
Tibialis anterior weight8.228.030.35.4-5.35.35.3-5.25.2-5.2-5.3-5.3-5.5
Time to tail flick, vehicle, before self-admin0.80.91.1-0.91.1-0.9-0.90.9-0.90.90.80.80.9
Time to tail flick, vehicle, after self-admin1.92.12.31.5-1.41.41.4-1.51.5-1.5-1.4-1.4-1.4
Time to tail flick, test, before self-admin0.90.81.2-1.01.1-1.0-1.00.7-0.70.71.01.00.9
Time to tail flick, test, after self-admin3.53.64.3-1.91.9-1.8-1.92.1-2.12.11.81.81.8
Delta time to tail flick, vehicle, before/after SA0.40.40.50.6-0.70.60.6-0.60.6-0.6-0.5-0.5-0.6
Delta time to tail flick, test, before/after SA0.40.40.8-0.50.4-0.5-0.50.9-0.90.90.40.40.5
Tibia length1.23.44.1-1.92.0-1.8-1.81.8-1.81.81.81.81.7
Ambulatory time before self-admin0.60.60.80.8-0.90.80.8-0.80.8-0.8-0.8-0.8-0.8
Ambulatory time after self-admin3.53.94.32.1-2.12.02.0-1.81.8-1.8-2.0-2.0-2.0
Bone: tissue strength0.10.10.1-0.30.2-0.3-0.30.3-0.30.30.30.30.2
Total heroin consumption0.30.40.50.6-0.40.60.6-0.70.7-0.7-0.7-0.7-0.6
Bone: trabecular number2.74.25.0-2.12.2-2.0-2.02.1-2.12.12.02.01.9
Bone: trabecular spacing2.43.13.31.8-1.81.81.8-1.71.7-1.7-1.8-1.8-1.6
Bone: trabecular thickness1.21.51.8-1.31.3-1.2-1.21.2-1.21.21.21.21.1
Bone: trabecular tissue density1.31.92.11.4-1.41.41.4-1.51.5-1.5-1.3-1.3-1.2
Water consumed over 24 hours1.31.61.71.3-1.21.31.3-1.21.2-1.2-1.3-1.3-1.3
Number of responses in last shaping day0.00.00.10.1-0.00.10.1-0.30.3-0.3-0.0-0.0-0.1