Hub : Genes

Mnt

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Mnt 0.02 0.02 8.8e-03 0.01 0.01 0.02 0.01 2.5e-02 1.4e-02 3.7e-03 1.7e-02
2 Brain gene expression Mnt 0.05 0.04 1.6e-03 0.02 0.02 0.04 0.02 2.2e-03 5.6e-03 1.0e-04 3.3e-03
3 NAcc intron excision ratio chr10_60207564_60209659 0.02 0.02 9.5e-04 0.01 0.01 0.01 0.01 2.6e-03 2.1e-03 2.1e-02 6.2e-03
4 NAcc isoform ratio NM_001105807.2 0.02 0.02 5.2e-03 0.01 0.01 0.01 0.01 4.4e-03 6.7e-03 1.1e-02 8.6e-03
5 NAcc gene expression Mnt 0.13 0.08 5.3e-13 0.08 0.07 0.06 0.08 4.7e-12 1.6e-10 2.1e-09 6.0e-12
6 IC gene expression Mnt 0.08 0.07 9.5e-03 0.06 0 0.05 0 2.5e-03 2.0e-01 5.4e-03 2.7e-01
7 PL intron excision ratio chr10_60204937_60209659 0.02 0.01 8.7e-03 0 0.01 0 0 1.5e-01 5.2e-02 1.2e-01 2.3e-01
8 NAcc mRNA stability Mnt 0.01 0.01 7.6e-03 0.02 0.01 0.01 0.01 1.3e-03 2.0e-03 7.1e-03 1.7e-03
9 LHb intron excision ratio chr10_60204937_60209659 0.33 0.21 6.1e-03 0.03 0.01 0.03 0.05 8.5e-02 1.6e-01 5.8e-02 2.9e-02
10 PL mRNA stability Mnt 0.06 0.05 3.2e-05 0.05 0.04 0.04 0.05 4.3e-06 9.7e-05 8.3e-05 9.1e-06
11 LHb intron excision ratio chr10_60207564_60209659 0.39 0.25 7.6e-03 0.07 0.03 0.03 0.05 1.2e-02 8.2e-02 6.2e-02 2.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density3.15.79.42.71.0-3.1-2.83.03.02.21.32.71.22.1
Area under the delay curve0.61.02.2-1.51.21.11.3-1.2-1.0-0.7-0.2-0.5-0.8-0.4
BMI with tail1.13.89.21.23.0-2.2-2.12.12.12.11.81.81.11.1
BMI without tail0.63.010.0-0.73.2-1.6-1.21.21.10.5-0.22.8-0.82.7
Body weight1.25.214.61.23.8-1.8-1.11.11.2-0.2-1.43.6-2.13.8
Weight adjusted by age0.41.12.70.10.9-1.1-0.90.91.11.51.61.00.90.4
Bone surface3.46.710.02.92.3-3.1-3.03.13.22.62.02.31.71.6
Bone volume3.36.610.02.42.3-3.2-3.13.13.22.72.02.31.71.6
Breakpoint value in progressive ratio session0.61.03.10.91.3-1.0-0.80.70.80.3-0.01.8-0.41.7
Number of licking bursts0.20.62.8-0.7-1.70.70.7-0.6-0.7-0.5-0.3-0.6-0.2-0.5
Context. condit. distance diff. score1.01.33.21.8-0.2-1.4-1.11.11.40.90.41.40.21.2
Locomotion velocity, session 11.61.84.40.5-0.5-1.8-1.61.61.30.7-0.22.1-0.02.0
Locomotion distance, session 10.60.81.6-0.9-1.3-1.0-1.11.20.80.80.30.70.80.5
Locomotion velocity, session 20.70.93.10.2-1.8-1.1-1.11.10.80.60.20.90.50.8
Locomotion distance, session 21.31.83.40.9-1.0-1.7-1.71.81.61.40.81.21.10.9
Locomotion velocity, session 34.24.88.6-2.0-0.92.72.6-2.7-2.9-2.6-2.0-1.8-1.6-1.1
Locomotion distance, session 30.40.52.51.51.60.0-0.20.10.10.30.4-0.30.6-0.4
Stereotopy head waving bouts, day 30.70.94.2-1.4-2.10.20.2-0.3-0.5-0.8-1.10.4-0.60.6
Stereotopy head waving duration, day 31.01.310.5-1.5-3.20.30.1-0.3-0.6-0.3-0.4-0.50.3-0.5
Locomotion velocity, session 71.21.32.8-0.51.7-1.2-1.11.11.31.41.40.70.90.3
Locomotion distance, session 72.02.53.8-0.42.0-1.8-1.61.62.01.91.91.41.20.7
Stereotopy head waving bouts, day 70.91.02.41.5-1.5-1.1-1.11.00.90.3-0.31.20.31.1
Stereotopy head waving duration, day 71.31.65.22.3-1.1-1.4-1.51.41.20.80.21.10.80.9
Locomotion velocity, session 81.01.25.72.4-1.8-0.8-0.90.90.90.70.30.40.70.2
Locomotion distance, session 81.62.44.91.7-0.7-2.0-1.61.71.91.10.32.20.31.9
Degree of sensitization distance1.21.24.9-2.20.1-1.2-0.80.81.10.80.61.5-0.11.1
Degree of sensitization stereotypy1.11.22.41.5-1.1-1.2-1.21.11.10.5-0.11.30.31.3
Conditioned locomotion0.60.73.60.3-1.90.70.3-0.4-0.7-0.5-0.4-1.00.3-0.9
Cocaine response after cond. corrected0.20.31.01.0-1.0-0.00.00.00.0-0.4-0.60.5-0.50.7
Cocaine response after cond. not corrected0.20.30.90.9-0.4-0.4-0.40.30.3-0.2-0.40.9-0.40.9
Cocaine response before conditioning0.81.01.7-0.21.3-1.2-1.31.11.10.90.71.10.50.9
Saline control response0.50.71.7-0.2-0.1-1.0-1.10.90.91.21.30.31.1-0.1
Bone: connectivity density5.28.213.13.51.4-3.5-3.43.53.62.71.72.91.72.2
Bone: cortical apparent density0.50.83.3-1.3-1.80.40.2-0.3-0.30.20.6-1.00.7-1.1
Bone: cortical area1.83.07.2-2.52.71.81.9-1.8-1.7-1.2-0.4-1.3-1.2-1.0
Bone: cortical porosity0.20.20.60.50.6-0.5-0.30.40.60.30.10.8-0.10.7
Bone: cortical porosity0.10.10.30.30.5-0.00.2-0.00.1-0.1-0.10.4-0.30.4
Bone: cortical thickness4.98.214.0-2.71.53.63.7-3.6-3.4-3.2-2.2-2.3-2.7-1.4
Bone: cortical thickness1.72.13.6-1.71.21.51.7-1.6-1.5-1.8-1.5-0.5-1.9-0.0
Bone: cortical tissue density0.40.73.7-1.1-1.90.30.1-0.1-0.20.30.5-0.80.7-0.9
Condit. Reinf. active minus inactive responses0.70.84.8-2.20.40.60.7-0.6-0.8-0.8-0.7-0.1-0.80.2
Condit. Reinf. active-inactive response ratio3.53.76.3-2.51.61.92.1-2.1-2.1-2.3-2.1-0.5-2.30.2
Condit. Reinf. active responses0.30.31.3-1.20.0-0.6-0.60.70.50.60.50.40.40.3
Condit. Reinf. inactive responses3.74.88.41.1-1.8-2.3-2.52.62.42.92.70.72.8-0.2
Incentive salience index mean0.50.72.4-1.60.90.50.6-0.4-0.7-0.9-1.00.1-0.90.5
Condit. Reinf. lever presses0.50.72.4-0.11.5-0.3-0.10.30.1-0.6-1.01.1-1.01.4
Condit. Reinf. active minus inactive responses0.71.12.91.31.7-1.0-0.90.91.21.21.20.60.60.3
Condit. Reinf. active-inactive response ratio0.20.31.51.20.90.20.4-0.3-0.1-0.3-0.20.1-0.60.2
Condit. Reinf. active responses1.72.55.00.71.8-1.6-1.61.61.82.12.20.61.60.0
Condit. Reinf. inactive responses3.14.510.1-0.71.0-2.2-2.52.42.23.03.20.52.7-0.4
Condit. Reinf. lever presses0.60.81.91.10.3-0.1-0.60.40.51.01.4-0.91.4-1.3
Condit. Reinf. lever reinforcers received2.02.85.70.72.4-1.6-1.61.61.82.22.40.51.7-0.1
Conditioned reinforcement - actives0.52.13.5-1.10.2-1.8-1.81.71.61.91.81.11.40.6
Conditioned reinforcement - inactives0.30.71.9-1.40.5-0.8-0.80.70.71.01.20.70.50.3
Conditioned locomotion0.40.63.4-0.61.90.30.1-0.1-0.20.20.7-0.80.4-1.0
Patch foraging indifference point 0 sec0.20.63.92.00.6-0.6-0.80.80.70.40.30.40.40.3
Patch foraging indifference point AUC0.20.41.4-0.4-1.20.10.10.00.20.60.9-0.70.8-0.9
Delay disc. indifference point, 0s delay0.50.62.41.31.5-0.5-0.50.50.60.60.50.50.40.4
Delay disc. indifference point, 16s delay0.81.25.7-2.41.21.01.2-1.2-0.9-0.40.3-0.7-0.6-0.7
Delay disc. indifference point, 2s delay0.50.51.0-0.6-0.11.01.0-1.0-0.9-0.7-0.4-0.5-0.7-0.3
Delay disc. indifference point, 24s delay0.20.31.9-0.71.40.40.5-0.5-0.4-0.10.3-0.2-0.3-0.2
Delay disc. indifference point, 4s delay0.50.51.1-0.20.70.81.0-1.0-0.7-0.7-0.40.1-1.00.2
Delay disc. indifference point, 8s delay0.40.61.7-1.30.50.91.1-1.1-0.7-0.7-0.4-0.2-0.8-0.0
Indifference point function ln k0.20.61.40.5-0.3-1.0-1.10.90.80.4-0.11.20.21.1
Indifference point function log k0.20.61.40.5-0.3-1.0-1.10.90.80.4-0.11.20.21.1
Patch foraging total patch changes 0 sec0.20.74.12.00.2-0.7-0.90.90.90.60.40.40.60.2
Patch foraging total patch changes 12 sec0.30.50.80.1-0.60.80.8-0.7-0.8-0.9-0.8-0.4-0.6-0.2
Patch foraging total patch changes 18 sec0.30.83.11.81.60.70.9-0.7-0.5-0.6-0.4-0.4-0.8-0.3
Patch foraging total patch changes 24 sec0.20.51.11.01.00.90.8-0.7-0.6-0.5-0.2-0.9-0.2-0.8
Patch foraging total patch changes 6 sec0.30.51.51.2-0.70.1-0.10.20.30.50.7-0.80.8-0.9
Patch foraging time to switch 0 sec0.62.24.41.20.41.41.6-1.5-1.6-2.1-2.0-0.5-2.10.1
Patch foraging water rate 0 sec0.31.34.3-2.1-0.6-0.6-0.90.90.81.31.3-0.21.6-0.6
Patch foraging water rate 12 sec0.10.63.7-1.91.3-0.2-0.10.10.20.30.30.5-0.00.4
Patch foraging water rate 18 sec1.53.45.1-2.1-0.2-2.2-2.32.22.12.11.61.61.71.0
Patch foraging water rate 24 sec0.71.06.5-2.50.8-0.5-0.80.70.50.80.8-0.01.0-0.2
Patch foraging water rate 6 sec0.30.42.7-1.6-0.10.40.2-0.2-0.30.10.4-0.60.5-0.7
Seeking ratio, delayed vs. immediate footshock0.40.51.60.6-0.60.80.7-0.7-0.5-0.10.4-1.20.4-1.3
Distance traveled before self-admin1.22.74.6-2.0-0.92.12.1-2.1-2.1-1.2-0.3-1.8-0.6-1.5
Distance traveled after self-admin0.81.412.6-3.50.20.70.7-0.7-0.9-0.3-0.0-0.3-0.3-0.3
Extensor digitorum longus weight4.116.227.42.7-1.3-5.1-5.25.25.04.83.63.04.01.7
Bone: elastic displacement0.30.41.3-0.5-0.40.60.5-0.5-0.5-0.10.2-1.10.3-1.1
Bone: elastic work4.15.48.6-2.21.32.92.8-2.8-2.8-2.6-1.9-2.2-1.8-1.5
Bone: endosteal estimation0.30.71.3-0.31.1-0.8-1.10.80.71.11.10.31.00.0
Bone: endosteal perimeter1.12.76.4-0.21.1-1.7-1.91.81.72.42.50.62.0-0.2
Epididymis fat weight3.819.433.44.52.3-5.7-4.95.05.33.82.25.81.24.7
Delta time in closed arm before/after self-admin1.31.29.41.1-3.10.50.3-0.3-0.30.20.3-0.80.7-0.8
Delta time in open arm before/after self-admin2.22.613.93.03.7-1.0-0.80.81.10.60.50.9-0.10.7
Diff in mean of infusions in LGA sessions0.61.03.11.80.6-1.0-1.00.90.90.3-0.31.4-0.11.4
Delay discount exponential model param0.60.92.21.5-1.1-1.1-1.21.20.90.70.30.40.80.3
Extinction: sum of active levers before priming2.03.04.51.50.7-2.1-2.02.02.02.11.91.71.51.0
Active lever presses in extinction session 62.22.23.50.90.6-1.9-1.81.71.81.71.41.71.11.2
Bone: final force1.93.116.10.14.01.41.5-1.6-1.4-1.8-1.6-0.1-1.90.4
Bone: final moment1.62.614.50.43.81.31.4-1.4-1.2-1.6-1.4-0.2-1.60.2
Food consumed during 24 hour testing period0.61.16.32.51.7-0.7-0.70.70.80.50.30.70.30.5
Glucose2.33.76.7-0.31.12.62.5-2.5-2.4-1.6-0.6-2.5-1.0-2.1
Heart weight1.32.18.02.81.7-1.2-0.90.91.10.1-0.61.9-0.51.9
Delay discount hyperbolic model param0.81.12.31.5-1.0-1.2-1.41.31.00.90.50.40.90.2
Intermittent access intake day 1-15 change0.31.98.02.81.20.1-0.00.10.41.01.7-1.51.4-1.9
Intermittent access intake escalation0.42.17.02.61.70.1-0.10.10.51.11.9-1.51.4-1.9
Intermittent access intake escalation 21.11.88.12.80.30.40.1-0.10.10.71.2-1.91.3-2.1
Intermitt. access day 1 inactive lever presses0.22.211.0-3.30.21.41.1-1.2-0.9-0.20.7-1.80.5-1.9
Intermitt. access day 15 inactive lever presses0.42.212.3-2.2-3.50.90.8-0.8-0.70.31.0-1.10.9-1.3
Intermitt. access escalation Index0.31.02.71.20.3-0.00.4-0.2-0.3-1.1-1.61.0-1.51.3
Intermittent access day 1 total infusions0.20.65.3-2.3-0.5-0.2-0.1-0.0-0.10.40.60.50.10.3
Intermittent access day 15 total infusions0.51.34.11.21.3-0.7-0.80.70.91.52.0-0.31.5-0.8
Intermittent access terminal intake (last 3 days)0.71.32.71.10.6-1.1-1.21.11.21.51.70.31.3-0.1
Intermittent access total infusions0.50.62.60.30.8-0.6-0.60.50.61.21.60.21.0-0.2
Intermittent access day 1 locomotion1.22.220.9-4.60.80.40.4-0.6-0.7-0.30.10.5-0.50.5
Intermittent access day 15 total locomotion0.20.85.8-2.41.00.30.2-0.3-0.30.41.0-0.50.4-0.7
Intermittent access total locomotion0.50.63.5-1.91.2-0.1-0.2-0.10.00.61.10.10.4-0.1
Intermittent access standard deviation0.42.27.40.50.1-0.6-0.90.81.12.02.7-0.92.4-1.6
Left kidney weight1.07.913.9-1.12.03.03.3-3.3-3.3-3.6-3.3-1.1-3.7-0.1
Right kidney weight1.17.415.5-2.01.22.63.1-3.1-3.1-3.6-3.4-0.2-3.90.8
Cocaine induced anxiety0.10.20.9-0.5-1.00.20.1-0.10.20.00.1-0.70.4-0.6
Post-drug Anxiety0.40.52.3-0.4-1.5-0.3-0.10.20.2-0.5-1.00.5-0.50.8
Baseline Anxiety0.40.72.20.7-0.9-0.8-0.50.60.3-0.1-0.71.3-0.51.5
Tail length0.94.612.41.72.1-0.20.4-0.4-0.3-2.0-3.12.8-3.13.5
Length with tail1.25.414.61.31.60.30.9-1.0-0.7-2.6-3.72.5-3.83.4
Length without tail0.21.33.91.20.7-0.5-0.10.10.3-0.7-1.51.6-1.62.0
Times rat made contact with spout2.12.46.4-2.02.51.41.4-1.6-1.5-1.6-1.4-0.4-1.70.1
Lifetime Intake0.50.62.0-0.80.7-0.5-0.60.40.51.11.40.30.9-0.0
Liver weight, left2.34.014.6-0.91.1-1.2-0.40.40.5-1.1-2.23.4-2.83.8
Liver weight, right2.13.713.90.81.4-1.5-0.90.91.1-0.4-1.53.5-2.03.7
Locomotor activity0.20.30.8-0.80.8-0.5-0.20.10.30.60.90.6-0.10.3
Locomotor testing distance0.00.10.30.1-0.6-0.3-0.20.10.20.30.50.2-0.00.0
Locomotor testing rearing0.31.32.71.60.6-1.1-1.11.11.11.51.6-0.01.1-0.5
Locomotion in novel chamber1.31.76.2-0.4-0.70.80.2-0.3-0.40.81.7-2.11.8-2.5
Locomotion in novel chamber post-restriction0.61.915.03.9-0.6-0.6-0.90.91.00.80.8-0.21.1-0.4
Fecal boli incidents, locomotor time 10.10.20.70.8-0.80.30.2-0.2-0.2-0.6-0.8-0.1-0.30.1
Change in fecal boli incidents, locomotor task0.40.50.70.50.80.70.7-0.8-0.7-0.8-0.7-0.4-0.8-0.2
Time >=10cm from walls, locomotor time 10.10.10.30.10.6-0.4-0.30.50.50.40.30.20.50.0
Bouts of movement, locomotor time 10.10.10.20.20.2-0.2-0.30.30.30.1-0.10.40.20.5
Total resting periods, locomotor time 10.10.10.20.0-0.2-0.3-0.30.30.30.30.10.30.40.3
Rest time, locomotor task time 10.20.41.6-1.3-0.90.40.2-0.3-0.4-0.1-0.0-0.90.3-0.8
Distance moved, locomotor task time 10.10.20.80.70.9-0.4-0.40.40.50.50.50.40.20.2
Vertical activity count, locomotor time 10.10.81.91.40.7-1.0-1.11.01.10.90.70.70.70.4
Time >=10cm from walls, locomotor time 20.41.17.1-1.12.70.90.9-0.8-0.7-0.6-0.3-0.3-0.5-0.2
Bouts of movement, locomotor time 20.10.21.2-1.10.70.20.2-0.2-0.2-0.10.10.1-0.30.2
Total resting periods, locomotor time 20.10.21.0-1.01.0-0.2-0.20.10.10.20.30.4-0.10.4
Rest time, locomotor task time 20.50.84.3-2.1-1.7-0.4-0.20.20.20.60.8-0.10.4-0.3
Distance moved, locomotor task time 20.20.20.50.60.50.1-0.10.20.30.30.5-0.50.7-0.6
Vertical activity count, locomotor time 20.10.31.11.00.10.50.4-0.3-0.3-0.7-0.8-0.3-0.2-0.1
Light reinforcement 10.10.53.01.71.1-0.3-0.30.30.50.30.3-0.20.2-0.3
Light reinforcement 21.53.48.9-3.0-1.02.02.1-2.0-2.1-2.0-1.6-1.0-1.7-0.5
Bone: marrow area0.30.71.2-0.31.1-0.8-1.10.80.61.01.10.30.90.0
Bone: maximum diameter0.51.15.4-0.92.3-0.3-0.40.40.41.01.6-0.31.0-0.7
Bone: maximum force1.32.710.4-0.43.21.51.6-1.7-1.5-1.8-1.5-0.4-1.80.1
Bone: maximum moment1.12.18.0-0.12.81.41.5-1.5-1.4-1.5-1.2-0.5-1.4-0.1
Mean time between licks in bursts0.10.41.1-0.7-0.3-0.00.1-0.2-0.2-0.6-1.00.8-1.01.1
Mean num. licks in bursts0.51.411.1-0.73.30.30.4-0.5-0.4-0.7-0.80.4-1.10.6
Cd content in liver1.61.84.3-1.1-1.3-1.2-1.21.31.41.92.10.31.5-0.3
Co content in liver1.11.310.7-3.31.60.30.5-0.5-0.4-0.10.40.0-0.30.0
Cu content in liver1.01.24.4-2.11.21.11.0-1.0-1.2-0.8-0.3-0.9-0.5-0.6
Fe content in liver0.30.41.10.10.1-0.00.2-0.1-0.2-0.7-1.10.7-1.00.9
K content in liver1.31.36.3-0.02.50.60.8-0.8-0.7-1.2-1.30.4-1.30.8
Mg content in liver0.50.63.5-0.81.9-0.4-0.40.40.40.60.80.10.6-0.1
Mn content in liver1.01.16.32.5-0.1-0.7-1.00.90.80.90.70.01.1-0.2
Na content in liver2.52.85.1-2.31.41.91.9-1.9-2.0-1.7-1.2-1.2-1.5-0.7
Rb content in liver4.04.67.42.21.9-2.4-2.42.52.72.52.11.52.00.8
Se content in liver0.60.71.2-1.11.10.90.9-0.8-0.9-0.8-0.6-0.6-0.5-0.3
Sr content in liver1.41.21.81.3-1.1-1.2-1.31.21.11.31.00.61.30.3
Zn content in liver0.30.31.8-1.30.8-0.2-0.10.0-0.0-0.2-0.30.6-0.50.7
Bone: minimum diameter0.91.88.6-2.90.71.21.4-1.4-1.4-1.1-0.7-0.4-1.4-0.2
Time in familiar zone, hab. session 11.21.32.90.9-0.7-1.1-1.31.21.31.51.40.11.7-0.4
Time in novel zone, hab. session 10.91.02.5-0.3-0.11.01.2-1.2-1.0-1.4-1.3-0.0-1.60.3
Total zone transitions, hab. session 12.33.25.10.1-2.1-1.9-2.12.12.02.21.90.72.3-0.0
Total locomotion distance, hab. session 11.01.44.9-1.4-2.2-1.1-1.11.21.11.20.80.71.00.3
Locomotion velocity, hab. session 11.11.64.9-1.8-2.2-1.1-1.21.31.01.20.90.61.20.2
Time in familiar zone, hab. session 21.61.82.9-0.5-0.5-1.6-1.71.71.61.71.40.91.50.4
Time in novel zone, hab. session 23.63.96.6-0.30.42.52.6-2.6-2.5-2.5-2.1-1.4-2.1-0.6
Total zone transitions, hab. session 21.01.32.11.3-1.4-1.3-1.31.41.21.00.40.90.80.7
Total locomotion distance, hab. session 20.50.64.3-1.3-2.1-0.2-0.20.3-0.1-0.1-0.60.3-0.10.4
Locomotion velocity, hab. session 20.40.64.1-1.3-2.0-0.1-0.10.2-0.2-0.2-0.60.2-0.10.3
Novel to familiar place preference ratio0.40.53.00.71.70.20.1-0.20.00.40.9-0.70.5-0.9
Novelty place preference0.20.31.80.71.30.20.2-0.2-0.00.10.4-0.40.1-0.4
Time in novel zone, NPP test0.20.21.60.81.2-0.1-0.10.00.20.30.5-0.10.1-0.2
Total zone transitions, NPP test1.31.92.91.1-1.2-1.5-1.61.71.61.71.30.71.60.2
Total locomotion distance, NPP test0.91.34.3-2.0-2.1-0.6-0.70.80.51.11.0-0.01.2-0.4
Locomotion velocity, NPP test0.91.24.7-2.0-2.2-0.2-0.40.50.20.91.0-0.51.2-0.8
Intraocular pressure1.11.86.7-0.40.6-0.5-0.50.70.81.92.6-0.92.0-1.6
Delta distance traveled before/after self-admin1.31.53.1-0.41.0-1.6-1.51.41.30.90.31.80.21.6
Delta ambulatory time before/after self-admin0.71.22.4-0.20.4-1.5-1.51.41.20.90.21.50.41.3
Parametrial fat weight4.811.320.94.01.2-4.4-3.93.83.82.30.74.60.34.1
Pavlov. Cond. lever latency0.40.61.40.7-0.9-0.5-0.80.60.50.90.8-0.31.2-0.5
Pavlov. Cond. magazine entry latency0.20.30.8-0.10.3-0.10.1-0.0-0.1-0.6-0.90.7-0.90.9
Pavlov. Cond. change in total contacts0.60.61.1-1.1-0.60.90.9-0.9-1.0-0.8-0.6-0.6-0.7-0.4
Pavlov. Cond. index score0.40.51.3-0.00.5-0.00.3-0.1-0.2-0.8-1.10.8-1.21.1
Pavlov. Cond. latency score0.60.82.3-0.10.80.10.5-0.4-0.4-1.0-1.30.9-1.51.2
Pavlov. Cond. lever contacts0.40.51.40.11.20.40.7-0.6-0.5-0.8-0.80.2-1.10.5
Pavlov. Cond. magazine entry number0.00.10.20.10.20.20.1-0.1-0.00.20.3-0.40.3-0.4
Pavlov. Cond. intertrial magazine entries0.91.12.70.6-1.3-0.7-1.00.90.81.41.5-0.31.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.30.9-0.10.3-0.00.2-0.1-0.2-0.7-0.90.7-0.90.9
Pavlov. Cond. response bias0.10.20.50.10.2-0.2-0.00.10.0-0.3-0.50.6-0.60.7
Pavlov. Cond. lever latency0.50.81.9-0.0-0.1-1.1-1.11.10.90.4-0.21.40.21.3
Pavlov. Cond. magazine entry latency1.01.42.40.30.61.41.5-1.6-1.3-1.5-1.2-0.6-1.4-0.2
Pavlov. Cond. change in total contacts0.41.13.0-0.41.71.21.2-1.2-1.1-0.7-0.3-1.1-0.6-0.9
Pavlov. Cond. index score0.71.12.30.10.61.51.4-1.4-1.2-0.7-0.1-1.5-0.4-1.4
Pavlov. Cond. latency score0.81.32.8-0.10.31.61.4-1.5-1.3-0.8-0.1-1.7-0.4-1.5
Pavlov. Cond. lever contacts0.30.50.80.20.60.90.9-0.9-0.7-0.5-0.1-0.9-0.5-0.8
Pavlov. Cond. magazine entry number1.21.52.6-0.1-1.4-1.5-1.61.61.31.41.00.91.30.5
Pavlov. Cond. intertrial magazine entries1.22.74.3-1.5-0.7-2.0-2.12.01.82.01.61.21.60.7
Pavlov. Cond. lever-magazine prob. diff.0.71.12.10.20.71.41.3-1.3-1.1-0.7-0.0-1.5-0.4-1.3
Pavlov. Cond. response bias0.71.01.80.21.11.31.3-1.4-1.0-0.8-0.3-1.0-0.9-0.8
Time in closed arm before self-admin0.50.92.20.90.2-1.0-1.00.90.7-0.1-1.01.3-0.31.5
Time in closed arm after self-admin0.91.06.3-0.2-2.50.80.7-0.8-0.9-0.9-1.1-0.4-0.4-0.1
Time in open arm before self-admin2.32.98.8-3.0-0.82.02.0-1.9-2.0-1.0-0.1-1.6-0.7-1.5
Time in open arm after self-admin1.82.013.52.03.70.50.6-0.6-0.30.31.2-0.80.0-1.2
Bone: periosteal estimation0.51.26.1-2.02.50.70.6-0.7-0.8-0.30.1-0.4-0.4-0.4
Bone: periosteal perimeter0.40.74.3-1.32.10.10.1-0.1-0.00.51.1-0.30.4-0.5
Bone: post-yield work0.20.41.2-0.10.7-0.6-0.40.50.50.0-0.41.1-0.31.1
Progressive ratio test 1 active lever presses0.40.74.1-2.00.6-0.2-0.10.10.10.81.30.40.70.1
Progressive ratio test 1 breakpoint0.40.74.4-2.10.4-0.2-0.20.20.20.91.30.40.80.1
Progressive ratio test 1 inactive lever presses0.51.47.6-2.8-1.11.21.0-1.2-1.0-0.20.4-0.90.2-1.0
Progressive ratio test 2 active lever presses1.42.06.1-1.4-0.7-1.2-1.11.11.02.02.51.11.80.4
Progressive ratio test 2 breakpoint1.62.16.1-1.5-0.7-1.2-1.21.11.02.12.51.11.80.4
Progressive ratio test 2 inactive lever presses0.41.24.7-2.2-1.1-0.2-0.10.10.31.31.90.41.2-0.1
Incentive Sensitization - Responses1.02.85.5-2.3-2.3-1.4-1.31.21.12.12.41.31.70.6
Incentive Sensitization - Breakpoint1.12.45.1-1.9-2.3-1.3-1.21.11.01.92.11.21.60.6
Sum of active levers in priming session hrs 5-62.62.510.9-0.23.3-1.6-1.21.21.10.90.72.1-0.21.9
Progressive ratio0.10.31.51.2-0.50.1-0.20.10.20.30.2-0.40.9-0.4
Food seeking constrained by brief footshock0.20.21.1-1.0-1.10.20.1-0.1-0.2-0.2-0.2-0.30.2-0.2
Seeking ratio, punishment vs. effort0.61.25.3-2.3-0.30.91.1-1.0-1.2-1.1-0.9-0.5-1.2-0.2
Retroperitoneal fat weight0.21.03.11.8-0.3-1.1-0.80.81.20.90.81.20.00.8
Reaction time number correct0.20.74.0-2.01.6-0.3-0.40.30.10.20.30.4-0.00.4
Reaction time mean minus median0.10.84.11.5-2.0-0.0-0.40.30.20.30.2-0.80.8-0.9
Reaction time mean minus median AUC0.31.75.00.9-2.2-1.1-1.51.41.21.41.1-0.11.7-0.4
Reaction time num false alarms0.91.53.11.6-1.3-0.5-0.90.70.71.41.6-0.91.8-1.4
Reaction time num false alarms AUC0.51.22.91.2-1.1-0.4-0.80.60.61.31.4-0.91.7-1.3
Reaction time trials correct on left0.20.74.0-2.01.6-0.3-0.40.30.10.20.30.4-0.00.4
Reaction time trials on left0.20.73.9-2.01.7-0.4-0.40.30.10.30.30.40.00.4
Reaction time mean0.20.44.00.0-2.00.20.1-0.2-0.2-0.2-0.4-0.5-0.1-0.4
Reaction time mean AUC0.20.64.3-0.2-2.10.40.2-0.4-0.3-0.2-0.3-0.90.1-0.8
Median of all reaction times0.30.43.0-0.6-1.70.40.4-0.5-0.4-0.4-0.6-0.4-0.5-0.2
Reaction time omissions0.00.00.10.20.2-0.3-0.30.30.20.10.0-0.0-0.00.0
Reaction time false alarm rate1.01.43.81.8-1.9-0.3-0.60.50.61.01.1-0.81.6-1.3
Reaction time premature initiation rate0.50.81.11.0-0.7-1.0-1.01.00.90.90.51.10.80.8
Reaction time premature initiations0.30.91.50.30.1-1.2-1.21.20.91.10.71.10.90.8
Std. dev. reaction times0.20.75.40.8-2.30.0-0.40.20.10.2-0.0-0.80.7-0.8
Reaction time trials completed0.20.73.9-2.01.7-0.4-0.40.30.10.30.30.40.00.4
Reaction time trials AUC0.20.84.0-2.01.9-0.3-0.40.30.10.30.40.30.00.3
Run reversals in cocaine runway, females0.60.74.6-0.1-2.1-0.1-0.30.30.20.60.6-0.31.2-0.4
Run reversals in cocaine runway, males1.31.44.82.2-0.1-0.8-0.90.90.91.41.7-0.41.3-0.8
Latency to leave start box in cocaine runway0.20.20.7-0.3-0.30.50.4-0.4-0.4-0.7-0.8-0.3-0.40.0
Latency to leave start box in cocaine runway, F0.50.72.8-0.6-0.80.50.4-0.5-0.5-1.2-1.70.1-0.90.6
Latency to leave start box in cocaine runway, M0.10.10.6-0.00.80.0-0.00.00.10.30.6-0.20.3-0.4
Std. dev. time between licks in bursts0.30.53.41.80.5-0.6-0.60.60.60.60.40.30.50.2
Total sessions with >9 infusions1.31.710.8-3.31.0-0.6-0.70.50.41.21.60.51.00.1
Short access day 1 total inactive lever presses0.30.76.50.12.5-0.2-0.30.20.20.40.50.20.20.1
Short access day 10 total inactive lever presses0.10.92.5-0.71.61.01.0-0.9-0.9-0.5-0.0-1.2-0.2-1.2
Short access day 1 total infusions0.51.07.3-2.70.50.20.0-0.2-0.20.71.2-0.50.9-0.8
Short access day 10 total infusions0.81.46.0-2.51.2-0.4-0.50.20.41.32.0-0.11.0-0.6
Short access total infusions0.50.74.8-2.20.10.1-0.1-0.1-0.10.71.2-0.40.8-0.6
Short access day 1 locomotion1.32.215.4-3.91.80.90.7-1.0-0.90.11.0-0.90.2-1.0
Short access day 10 total locomotion0.31.37.7-2.81.50.70.4-0.7-0.60.10.8-0.80.2-1.0
Short access total locomotion1.92.821.0-4.61.61.00.6-1.0-1.00.21.2-1.00.4-1.2
One hour access (0.3 mA shock)1.51.83.41.5-0.0-1.4-1.31.31.51.81.80.91.50.4
Compulsive drug intake0.81.25.72.4-0.5-0.5-0.40.40.1-0.6-1.31.3-0.81.6
One hour access (shock baseline)0.41.15.4-2.30.7-0.4-0.30.30.61.21.6-0.11.0-0.5
Social response proportion1.31.66.30.50.8-0.9-0.60.60.5-0.6-1.52.2-1.22.5
Social responses1.01.43.31.20.8-1.4-1.21.21.20.4-0.41.8-0.21.8
Social time1.52.49.63.1-0.7-1.6-1.61.61.60.4-0.71.60.11.7
Soleus weight1.85.413.91.01.6-3.0-2.52.52.61.30.13.7-0.33.5
Bone: stiffness0.81.45.41.32.3-0.7-0.40.40.6-0.3-0.81.6-0.91.7
Tibialis anterior weight6.321.837.23.80.4-6.1-6.06.05.95.13.64.43.83.0
Time to tail flick, vehicle, before self-admin3.64.58.21.0-0.3-2.9-2.92.82.62.11.12.41.51.9
Time to tail flick, vehicle, after self-admin0.40.74.22.0-1.2-0.6-0.70.70.60.3-0.20.40.40.4
Time to tail flick, test, before self-admin1.01.24.72.2-1.7-0.4-0.70.70.5-0.6-1.60.5-0.10.9
Time to tail flick, test, after self-admin0.50.51.30.9-1.00.50.5-0.5-0.7-0.8-1.1-0.2-0.70.1
Delta time to tail flick, vehicle, before/after SA0.91.02.91.2-0.11.20.9-0.9-0.9-0.7-0.5-1.70.0-1.6
Delta time to tail flick, test, before/after SA0.30.41.6-0.90.30.20.3-0.3-0.30.71.3-0.50.4-0.9
Tibia length1.23.48.83.01.61.01.4-1.3-1.1-2.2-2.60.5-2.61.2
Ambulatory time before self-admin1.33.87.1-1.7-0.32.62.7-2.6-2.5-1.9-1.1-1.8-1.5-1.3
Ambulatory time after self-admin0.91.46.9-2.60.60.70.9-0.9-1.1-1.1-1.10.2-1.30.5
Bone: tissue strength1.81.93.10.71.01.81.7-1.7-1.7-1.6-1.3-1.1-1.1-0.6
Total heroin consumption3.64.29.92.50.7-2.5-2.12.12.21.40.73.20.32.8
Bone: trabecular number3.56.511.93.40.6-3.2-3.03.13.22.31.42.61.42.0
Bone: trabecular spacing0.50.72.4-0.41.60.90.8-0.9-0.8-0.30.3-0.9-0.1-0.9
Bone: trabecular thickness0.30.41.01.0-0.4-0.8-0.80.80.80.4-0.10.70.30.6
Bone: trabecular tissue density1.42.53.9-1.2-1.72.01.9-1.9-1.9-1.5-1.0-1.7-0.8-1.3
Water consumed over 24 hours0.71.32.8-1.10.70.91.0-1.1-1.1-1.6-1.70.1-1.60.6
Number of responses in last shaping day1.21.57.1-0.82.70.90.7-0.8-0.70.31.2-1.40.5-1.7