Hub : Genes

Krt77

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Krt77 0.16 0.1 1.8e-03 0.09 0.15 0.15 0.14 4.6e-03 2.2e-04 2.1e-04 4.1e-04
2 pVTA gene expression Krt77 0.06 0.04 1.0e-05 0.06 0.07 0.06 0.06 2.8e-05 2.5e-06 6.3e-06 5.7e-06
3 IL gene expression Krt77 0.29 0.18 6.4e-03 0.02 -0 0.01 -0.01 9.1e-02 4.2e-01 2.2e-01 5.5e-01
4 PL gene expression Krt77 0.08 0.05 1.9e-05 0.06 0.04 0.05 0.04 9.9e-07 2.8e-05 9.3e-06 2.2e-05
5 Brain gene expression Krt77 0.1 0.08 3.4e-05 0.06 0.05 0.06 0.05 5.7e-06 1.7e-05 5.5e-06 3.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5
Bone: apparent density0.30.51.51.2-0.70.20.1-0.7
Area under the delay curve0.10.10.30.4-0.60.10.40.0
BMI with tail1.45.09.63.1-2.52.31.90.3
BMI without tail0.31.62.31.5-1.51.31.00.8
Body weight0.20.82.21.5-1.10.70.5-0.3
Weight adjusted by age0.00.10.3-0.60.3-0.3-0.4-0.2
Bone surface0.81.54.42.1-1.40.80.80.0
Bone volume0.81.74.32.1-1.50.90.90.1
Breakpoint value in progressive ratio session0.61.12.51.6-1.10.81.00.3
Number of licking bursts0.20.62.6-0.0-0.30.40.61.6
Context. condit. distance diff. score0.10.20.40.6-0.40.30.40.1
Locomotion velocity, session 14.95.58.5-2.92.7-2.5-2.3-0.6
Locomotion distance, session 11.72.24.7-2.21.7-1.4-1.30.3
Locomotion velocity, session 24.25.06.8-2.62.4-2.4-2.4-1.0
Locomotion distance, session 21.62.23.7-1.91.9-1.4-1.4-0.1
Locomotion velocity, session 34.35.06.4-2.52.5-2.4-2.4-1.1
Locomotion distance, session 33.43.85.0-2.02.2-2.1-2.1-1.1
Stereotopy head waving bouts, day 32.12.53.11.8-1.71.61.61.2
Stereotopy head waving duration, day 30.10.10.30.6-0.40.20.30.3
Locomotion velocity, session 70.10.10.3-0.50.6-0.3-0.10.2
Locomotion distance, session 72.33.05.6-2.42.0-1.5-1.7-0.2
Stereotopy head waving bouts, day 73.94.55.72.2-2.22.12.41.7
Stereotopy head waving duration, day 72.32.93.71.9-1.81.51.81.3
Locomotion velocity, session 80.00.00.1-0.00.2-0.2-0.10.3
Locomotion distance, session 81.52.13.3-1.81.7-1.5-1.4-0.3
Degree of sensitization distance0.40.40.70.2-0.60.80.70.8
Degree of sensitization stereotypy2.52.83.61.7-1.81.51.91.3
Conditioned locomotion0.60.70.9-0.51.0-0.9-0.9-0.7
Cocaine response after cond. corrected0.10.20.6-0.80.5-0.3-0.30.3
Cocaine response after cond. not corrected0.20.30.5-0.70.7-0.4-0.4-0.3
Cocaine response before conditioning0.30.30.8-0.20.6-0.6-0.4-0.9
Saline control response0.00.10.10.20.10.00.3-0.4
Bone: connectivity density0.20.31.10.50.1-0.3-0.4-1.0
Bone: cortical apparent density0.50.81.6-0.0-0.51.10.91.3
Bone: cortical area0.71.12.31.5-1.11.10.8-0.2
Bone: cortical porosity1.31.41.7-0.81.2-1.3-1.3-1.3
Bone: cortical porosity1.31.52.1-0.81.2-1.3-1.2-1.5
Bone: cortical thickness0.10.20.50.5-0.40.70.3-0.0
Bone: cortical thickness1.92.32.7-1.61.6-1.3-1.5-1.6
Bone: cortical tissue density0.40.61.4-0.1-0.41.00.71.2
Condit. Reinf. active minus inactive responses0.40.50.6-0.70.8-0.8-0.7-0.6
Condit. Reinf. active-inactive response ratio0.70.81.0-0.80.8-1.0-0.8-0.9
Condit. Reinf. active responses1.11.41.9-1.21.4-1.2-1.2-0.9
Condit. Reinf. inactive responses0.91.22.0-1.21.4-0.9-1.1-0.6
Incentive salience index mean0.10.10.1-0.30.3-0.3-0.2-0.2
Condit. Reinf. lever presses0.40.61.00.5-0.70.80.71.0
Condit. Reinf. active minus inactive responses1.01.62.31.2-1.21.51.40.9
Condit. Reinf. active-inactive response ratio0.30.40.50.6-0.70.70.70.4
Condit. Reinf. active responses1.72.53.01.4-1.51.71.71.4
Condit. Reinf. inactive responses0.30.40.80.5-0.40.70.70.9
Condit. Reinf. lever presses0.10.10.2-0.40.5-0.2-0.1-0.5
Condit. Reinf. lever reinforcers received0.71.01.40.9-0.91.11.21.0
Conditioned reinforcement - actives0.21.03.5-0.5-0.30.70.81.9
Conditioned reinforcement - inactives0.10.40.9-0.90.7-0.4-0.3-0.3
Conditioned locomotion0.40.52.0-0.4-0.30.40.51.4
Patch foraging indifference point 0 sec0.20.41.0-1.00.7-0.2-0.20.8
Patch foraging indifference point AUC0.20.41.1-0.6-0.30.00.71.1
Delay disc. indifference point, 0s delay0.00.00.1-0.10.1-0.1-0.3-0.1
Delay disc. indifference point, 16s delay0.10.10.20.4-0.50.10.4-0.4
Delay disc. indifference point, 2s delay5.66.36.92.3-2.62.52.52.5
Delay disc. indifference point, 24s delay0.10.10.2-0.2-0.50.00.50.3
Delay disc. indifference point, 4s delay0.40.40.80.9-0.80.50.70.1
Delay disc. indifference point, 8s delay0.10.10.2-0.30.2-0.5-0.4-0.5
Indifference point function ln k0.20.51.41.2-0.10.1-0.5-0.9
Indifference point function log k0.20.51.41.2-0.10.1-0.5-0.9
Patch foraging total patch changes 0 sec0.30.92.0-1.41.1-0.7-0.70.5
Patch foraging total patch changes 12 sec0.30.41.0-1.00.40.10.30.9
Patch foraging total patch changes 18 sec0.30.81.8-1.30.5-0.10.21.3
Patch foraging total patch changes 24 sec0.20.72.4-0.5-0.30.40.91.6
Patch foraging total patch changes 6 sec0.71.24.7-1.10.10.40.42.2
Patch foraging time to switch 0 sec0.10.20.60.2-0.20.80.30.5
Patch foraging water rate 0 sec0.00.00.10.1-0.1-0.20.1-0.1
Patch foraging water rate 12 sec0.20.60.8-0.50.8-0.8-0.9-0.9
Patch foraging water rate 18 sec0.00.00.10.1-0.00.30.20.1
Patch foraging water rate 24 sec0.50.81.10.9-0.81.10.80.7
Patch foraging water rate 6 sec0.30.52.00.4-0.0-0.4-0.2-1.4
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.00.4-0.2-0.4-0.4
Distance traveled before self-admin0.00.00.10.0-0.2-0.20.1-0.1
Distance traveled after self-admin0.30.51.4-0.60.5-0.6-0.2-1.2
Extensor digitorum longus weight5.722.629.95.1-5.54.74.53.8
Bone: elastic displacement2.83.54.6-2.12.1-2.0-2.0-0.9
Bone: elastic work2.83.75.0-2.01.9-2.1-2.2-1.2
Bone: endosteal estimation0.61.54.02.0-1.50.70.9-0.0
Bone: endosteal perimeter0.71.84.42.1-1.71.01.1-0.0
Epididymis fat weight2.010.214.6-2.22.9-3.5-3.3-3.8
Delta time in closed arm before/after self-admin0.60.61.41.2-0.70.70.70.0
Delta time in open arm before/after self-admin4.75.56.2-2.32.4-2.4-2.5-2.1
Diff in mean of infusions in LGA sessions0.10.10.30.6-0.40.50.1-0.0
Delay discount exponential model param0.20.30.6-0.50.8-0.2-0.6-0.2
Extinction: sum of active levers before priming1.01.53.01.7-1.51.00.90.8
Active lever presses in extinction session 60.10.10.20.5-0.40.00.20.1
Bone: final force0.40.71.91.4-1.10.50.4-0.3
Bone: final moment0.50.92.31.5-1.20.50.4-0.3
Food consumed during 24 hour testing period0.20.51.1-0.00.5-0.7-0.6-1.1
Glucose0.30.50.8-0.90.9-0.6-0.80.2
Heart weight0.40.72.70.50.2-0.4-0.4-1.6
Delay discount hyperbolic model param0.30.40.8-0.70.9-0.4-0.7-0.3
Intermittent access intake day 1-15 change0.00.10.2-0.30.3-0.5-0.3-0.0
Intermittent access intake escalation0.00.10.2-0.00.2-0.4-0.2-0.1
Intermittent access intake escalation 20.10.20.3-0.10.4-0.4-0.4-0.5
Intermitt. access day 1 inactive lever presses0.11.31.81.2-1.21.31.40.2
Intermitt. access day 15 inactive lever presses0.00.10.50.10.2-0.1-0.3-0.7
Intermitt. access escalation Index1.34.06.01.3-1.82.22.02.4
Intermittent access day 1 total infusions0.10.41.2-0.2-0.20.30.81.1
Intermittent access day 15 total infusions0.30.62.7-0.5-0.00.10.51.7
Intermittent access terminal intake (last 3 days)0.71.23.60.0-0.50.81.11.9
Intermittent access total infusions1.31.54.50.2-0.70.81.32.1
Intermittent access day 1 locomotion0.40.72.1-0.2-0.50.41.11.5
Intermittent access day 15 total locomotion0.20.81.8-0.70.7-1.4-0.7-0.9
Intermittent access total locomotion0.10.10.3-0.1-0.2-0.20.50.6
Intermittent access standard deviation0.31.32.4-1.21.1-1.5-0.9-0.8
Left kidney weight0.00.31.1-0.20.2-0.3-0.5-1.0
Right kidney weight0.00.31.00.2-0.3-0.2-0.3-1.0
Cocaine induced anxiety0.00.10.30.3-0.4-0.00.20.6
Post-drug Anxiety0.10.10.30.6-0.30.10.1-0.5
Baseline Anxiety0.40.72.90.10.6-0.2-0.6-1.7
Tail length0.21.32.2-1.51.3-1.2-1.1-0.1
Length with tail0.21.01.4-0.90.9-1.2-1.0-0.9
Length without tail0.10.31.20.6-0.0-0.3-0.4-1.1
Times rat made contact with spout0.30.40.8-0.00.4-0.8-0.6-0.9
Lifetime Intake1.01.23.30.2-0.70.71.31.8
Liver weight, left0.71.33.71.9-1.30.60.4-0.7
Liver weight, right0.30.51.90.20.1-0.4-0.6-1.4
Locomotor activity0.00.00.0-0.20.2-0.1-0.10.2
Locomotor testing distance0.10.20.3-0.60.4-0.4-0.30.6
Locomotor testing rearing0.10.51.2-0.80.5-1.1-0.8-0.0
Locomotion in novel chamber2.22.94.42.1-2.11.61.51.1
Locomotion in novel chamber post-restriction0.72.12.90.9-1.31.71.61.6
Fecal boli incidents, locomotor time 11.54.05.0-2.22.1-2.2-2.0-1.4
Change in fecal boli incidents, locomotor task1.01.01.61.0-0.91.10.81.3
Time >=10cm from walls, locomotor time 10.40.61.0-0.41.0-0.8-0.7-0.7
Bouts of movement, locomotor time 10.30.40.6-0.80.8-0.7-0.3-0.1
Total resting periods, locomotor time 11.11.21.9-1.41.4-1.2-0.9-0.4
Rest time, locomotor task time 10.60.91.9-1.40.8-1.0-0.70.7
Distance moved, locomotor task time 10.71.93.31.4-1.31.81.40.6
Vertical activity count, locomotor time 10.32.22.91.3-1.61.71.70.9
Time >=10cm from walls, locomotor time 20.00.10.1-0.30.30.2-0.0-0.1
Bouts of movement, locomotor time 20.92.83.41.7-1.81.81.81.2
Total resting periods, locomotor time 20.83.44.01.9-1.92.02.01.4
Rest time, locomotor task time 20.20.40.6-0.80.5-0.4-0.50.8
Distance moved, locomotor task time 20.10.10.40.3-0.00.40.1-0.6
Vertical activity count, locomotor time 20.10.30.60.4-0.60.50.80.3
Light reinforcement 10.10.41.2-0.70.20.50.41.1
Light reinforcement 20.30.61.8-1.30.9-0.6-0.50.2
Bone: marrow area0.61.43.82.0-1.50.70.8-0.1
Bone: maximum diameter0.71.42.61.6-1.31.11.10.4
Bone: maximum force0.81.52.81.7-1.51.10.90.7
Bone: maximum moment0.81.63.01.7-1.61.10.90.7
Mean time between licks in bursts0.10.81.5-1.20.9-0.8-0.80.6
Mean num. licks in bursts0.71.85.3-0.20.9-1.2-1.2-2.3
Cd content in liver0.10.10.2-0.30.5-0.4-0.40.2
Co content in liver0.30.41.00.5-0.60.30.51.0
Cu content in liver2.83.36.92.6-2.01.61.80.4
Fe content in liver0.20.20.8-0.2-0.30.30.20.9
K content in liver0.10.10.30.1-0.5-0.10.20.6
Mg content in liver0.10.10.30.0-0.2-0.20.10.5
Mn content in liver0.10.10.3-0.50.0-0.1-0.10.6
Na content in liver0.40.41.11.0-0.70.40.40.4
Rb content in liver0.60.70.91.0-0.80.60.81.0
Se content in liver0.60.71.5-1.20.8-0.7-0.8-0.4
Sr content in liver0.90.81.9-0.10.6-1.4-0.9-0.8
Zn content in liver0.60.70.9-0.71.0-0.9-0.7-1.0
Bone: minimum diameter0.91.84.02.0-1.51.11.1-0.2
Time in familiar zone, hab. session 11.01.01.4-0.70.9-1.1-1.2-1.2
Time in novel zone, hab. session 12.32.53.31.2-1.51.71.81.7
Total zone transitions, hab. session 10.40.51.00.1-0.20.90.81.0
Total locomotion distance, hab. session 10.71.01.8-1.31.3-0.8-0.8-0.7
Locomotion velocity, hab. session 10.81.11.7-1.31.3-0.8-1.0-0.6
Time in familiar zone, hab. session 20.10.10.20.4-0.1-0.3-0.4-0.2
Time in novel zone, hab. session 20.40.50.70.3-0.50.80.90.9
Total zone transitions, hab. session 20.40.51.1-1.10.9-0.6-0.50.1
Total locomotion distance, hab. session 21.31.72.2-1.41.5-1.1-1.3-1.2
Locomotion velocity, hab. session 21.72.32.8-1.61.7-1.4-1.5-1.4
Novel to familiar place preference ratio0.30.40.50.7-0.60.70.6-0.2
Novelty place preference0.20.20.40.6-0.50.50.50.0
Time in novel zone, NPP test0.30.40.60.8-0.70.70.70.1
Total zone transitions, NPP test1.21.84.6-2.11.6-1.0-1.00.0
Total locomotion distance, NPP test3.85.38.8-3.02.6-2.1-2.1-1.5
Locomotion velocity, NPP test4.36.29.9-3.12.7-2.3-2.3-1.7
Intraocular pressure0.20.31.0-0.30.10.40.41.0
Delta distance traveled before/after self-admin3.13.47.2-1.41.7-1.6-1.5-2.7
Delta ambulatory time before/after self-admin1.72.98.0-1.01.5-1.3-1.3-2.8
Parametrial fat weight0.30.71.1-1.10.9-0.9-0.5-0.3
Pavlov. Cond. lever latency2.53.24.1-1.51.7-1.9-1.8-2.0
Pavlov. Cond. magazine entry latency3.34.25.81.6-2.02.12.12.4
Pavlov. Cond. change in total contacts4.24.65.12.1-2.32.22.21.9
Pavlov. Cond. index score5.46.88.02.2-2.72.62.72.8
Pavlov. Cond. latency score5.56.97.72.3-2.72.72.72.8
Pavlov. Cond. lever contacts2.83.44.91.4-1.81.91.92.2
Pavlov. Cond. magazine entry number2.53.24.4-1.41.7-1.8-1.8-2.1
Pavlov. Cond. intertrial magazine entries2.02.33.0-1.61.7-1.5-1.5-1.3
Pavlov. Cond. lever-magazine prob. diff.5.56.88.62.2-2.62.62.72.9
Pavlov. Cond. response bias1.82.33.91.1-1.41.41.52.0
Pavlov. Cond. lever latency1.01.42.11.5-1.31.10.90.9
Pavlov. Cond. magazine entry latency3.24.65.6-2.42.3-2.1-2.2-1.7
Pavlov. Cond. change in total contacts0.30.81.50.8-0.81.21.10.4
Pavlov. Cond. index score1.62.53.7-1.91.8-1.5-1.4-1.2
Pavlov. Cond. latency score1.52.43.8-1.91.8-1.4-1.4-1.2
Pavlov. Cond. lever contacts1.72.43.1-1.81.8-1.6-1.3-1.3
Pavlov. Cond. magazine entry number1.11.41.71.3-1.31.01.21.1
Pavlov. Cond. intertrial magazine entries0.30.71.3-0.60.8-1.1-0.8-0.6
Pavlov. Cond. lever-magazine prob. diff.1.21.92.8-1.71.5-1.2-1.2-1.2
Pavlov. Cond. response bias1.52.02.5-1.61.6-1.5-1.2-1.2
Time in closed arm before self-admin0.30.50.80.4-0.70.80.70.9
Time in closed arm after self-admin3.94.45.11.8-2.12.12.32.2
Time in open arm before self-admin2.02.43.21.2-1.61.51.81.6
Time in open arm after self-admin1.71.92.3-1.21.3-1.4-1.4-1.5
Bone: periosteal estimation1.02.45.72.4-1.81.21.2-0.1
Bone: periosteal perimeter1.42.85.62.4-2.01.51.40.3
Bone: post-yield work0.61.11.71.3-1.11.00.90.7
Progressive ratio test 1 active lever presses0.61.13.3-1.30.3-0.10.51.8
Progressive ratio test 1 breakpoint0.61.03.0-1.30.3-0.20.51.7
Progressive ratio test 1 inactive lever presses0.30.81.40.3-0.81.01.20.9
Progressive ratio test 2 active lever presses1.01.42.50.6-1.01.01.61.5
Progressive ratio test 2 breakpoint1.41.82.90.7-1.21.11.71.6
Progressive ratio test 2 inactive lever presses0.10.20.50.2-0.40.20.70.3
Incentive Sensitization - Responses0.51.31.81.3-1.30.91.40.7
Incentive Sensitization - Breakpoint0.71.72.31.5-1.41.11.50.8
Sum of active levers in priming session hrs 5-60.20.20.30.3-0.40.50.40.2
Progressive ratio0.10.20.70.2-0.30.40.30.8
Food seeking constrained by brief footshock0.60.71.90.2-0.71.01.40.5
Seeking ratio, punishment vs. effort0.10.10.30.0-0.10.20.4-0.6
Retroperitoneal fat weight1.98.510.2-3.23.1-3.2-2.8-2.3
Reaction time number correct0.20.91.6-0.90.8-1.3-1.1-0.1
Reaction time mean minus median0.00.00.1-0.3-0.00.30.1-0.1
Reaction time mean minus median AUC0.00.10.2-0.1-0.40.40.40.5
Reaction time num false alarms0.71.22.1-1.51.4-0.9-0.8-0.6
Reaction time num false alarms AUC0.40.92.1-1.41.2-0.6-0.6-0.4
Reaction time trials correct on left0.20.91.6-0.90.8-1.3-1.1-0.1
Reaction time trials on left0.31.01.8-1.00.9-1.3-1.2-0.2
Reaction time mean0.20.40.80.7-0.50.50.4-0.9
Reaction time mean AUC0.20.40.80.7-0.50.50.3-0.9
Median of all reaction times0.30.51.40.9-0.50.40.3-1.2
Reaction time omissions2.03.36.9-1.61.4-1.7-1.5-2.6
Reaction time false alarm rate0.10.10.2-0.40.30.50.4-0.0
Reaction time premature initiation rate0.40.61.8-0.20.8-0.7-0.5-1.4
Reaction time premature initiations0.51.52.1-0.71.2-1.4-1.2-1.4
Std. dev. reaction times0.00.10.2-0.0-0.30.30.2-0.4
Reaction time trials completed0.31.01.8-1.00.9-1.3-1.2-0.2
Reaction time trials AUC0.20.71.4-0.80.7-1.2-1.0-0.1
Run reversals in cocaine runway, females0.50.62.50.10.4-0.4-0.3-1.6
Run reversals in cocaine runway, males0.40.51.8-0.1-0.50.40.31.3
Latency to leave start box in cocaine runway0.30.40.70.8-0.60.60.60.5
Latency to leave start box in cocaine runway, F0.20.20.60.2-0.30.30.50.7
Latency to leave start box in cocaine runway, M0.70.61.61.3-0.70.90.5-0.1
Std. dev. time between licks in bursts0.81.52.6-1.61.2-1.4-1.20.2
Total sessions with >9 infusions0.81.01.90.4-0.80.81.41.2
Short access day 1 total inactive lever presses0.00.10.20.1-0.20.30.40.3
Short access day 10 total inactive lever presses0.10.81.41.2-0.51.00.5-1.0
Short access day 1 total infusions0.10.20.50.2-0.40.30.7-0.2
Short access day 10 total infusions0.61.02.30.5-0.60.81.31.5
Short access total infusions0.50.61.30.2-0.60.61.11.1
Short access day 1 locomotion0.10.20.40.2-0.50.10.70.1
Short access day 10 total locomotion0.00.20.40.6-0.40.30.6-0.1
Short access total locomotion0.30.51.00.2-0.60.51.00.8
One hour access (0.3 mA shock)2.52.93.71.3-1.91.51.91.8
Compulsive drug intake1.62.43.21.6-1.61.81.70.6
One hour access (shock baseline)0.40.91.90.6-1.00.71.01.4
Social response proportion1.82.22.7-1.61.4-1.5-1.4-1.7
Social responses1.11.52.8-1.71.2-1.1-1.1-0.8
Social time2.23.54.2-1.61.6-2.1-1.9-2.0
Soleus weight0.00.10.40.1-0.2-0.6-0.3-0.3
Bone: stiffness2.24.06.52.5-2.41.91.81.0
Tibialis anterior weight7.626.131.15.3-5.65.25.14.2
Time to tail flick, vehicle, before self-admin0.20.30.60.3-0.60.80.50.2
Time to tail flick, vehicle, after self-admin0.10.20.60.2-0.1-0.8-0.4-0.6
Time to tail flick, test, before self-admin0.10.20.3-0.60.3-0.5-0.2-0.2
Time to tail flick, test, after self-admin0.50.61.61.2-0.70.50.1-0.8
Delta time to tail flick, vehicle, before/after SA0.30.41.1-0.00.3-1.0-0.6-0.5
Delta time to tail flick, test, before/after SA0.40.51.11.0-0.50.70.0-0.9
Tibia length0.30.82.01.4-0.60.80.3-1.0
Ambulatory time before self-admin0.00.00.10.0-0.0-0.2-0.00.2
Ambulatory time after self-admin0.40.62.6-0.10.5-0.5-0.3-1.6
Bone: tissue strength1.92.02.41.3-1.51.41.31.5
Total heroin consumption0.60.71.61.3-1.00.80.7-0.2
Bone: trabecular number0.20.41.20.20.2-0.5-0.6-1.1
Bone: trabecular spacing1.01.52.01.0-1.01.41.41.2
Bone: trabecular thickness0.00.00.00.10.00.1-0.1-0.1
Bone: trabecular tissue density1.11.92.70.7-1.21.61.61.6
Water consumed over 24 hours0.10.20.5-0.20.3-0.7-0.4-0.1
Number of responses in last shaping day2.73.55.2-1.81.9-2.3-1.9-1.5