A transcriptomic model was trained for each RNA phenotype in each tissue. The table below includes models with cis-heritability P-value < 0.01, which were used for TWAS association testing. Thus, for single phenotype modalities such as expression level, there are 0 or 1 models per gene per tissue, while for multi-phenotype modalities such as isoform ratio, there may be multiple models per gene per tissue.
| Tissue | Modality | Sample size | Models |
|---|---|---|---|
| Adipose | alternative polyA | 411 | 3710 |
| Adipose | alternative TSS | 411 | 3793 |
| Adipose | gene expression | 411 | 9929 |
| Adipose | isoform ratio | 411 | 4864 |
| Adipose | intron excision ratio | 411 | 3179 |
| Adipose | mRNA stability | 411 | 4409 |
| BLA | alternative polyA | 189 | 2209 |
| BLA | alternative TSS | 189 | 2009 |
| BLA | gene expression | 189 | 7126 |
| BLA | isoform ratio | 189 | 3028 |
| BLA | intron excision ratio | 189 | 3392 |
| BLA | mRNA stability | 189 | 2377 |
| Brain | alternative polyA | 342 | 3732 |
| Brain | alternative TSS | 342 | 4086 |
| Brain | gene expression | 342 | 10716 |
| Brain | isoform ratio | 342 | 5595 |
| Brain | intron excision ratio | 342 | 6066 |
| Brain | mRNA stability | 342 | 5392 |
| Eye | alternative polyA | 53 | 269 |
| Eye | alternative TSS | 53 | 430 |
| Eye | gene expression | 53 | 1272 |
| Eye | isoform ratio | 53 | 563 |
| Eye | intron excision ratio | 53 | 910 |
| Eye | mRNA stability | 53 | 367 |
| IC | alternative polyA | 148 | 1856 |
| IC | alternative TSS | 148 | 1782 |
| IC | gene expression | 148 | 6594 |
| IC | isoform ratio | 148 | 2611 |
| IC | intron excision ratio | 148 | 3555 |
| IC | mRNA stability | 148 | 1566 |
| IL | alternative polyA | 83 | 1160 |
| IL | alternative TSS | 83 | 755 |
| IL | gene expression | 83 | 4449 |
| IL | isoform ratio | 83 | 1283 |
| IL | intron excision ratio | 83 | 1210 |
| IL | mRNA stability | 83 | 1359 |
| LHb | alternative polyA | 82 | 1101 |
| LHb | alternative TSS | 82 | 692 |
| LHb | gene expression | 82 | 3922 |
| LHb | isoform ratio | 82 | 1258 |
| LHb | intron excision ratio | 82 | 1239 |
| LHb | mRNA stability | 82 | 1252 |
| Liver | alternative polyA | 411 | 2574 |
| Liver | alternative TSS | 411 | 2892 |
| Liver | gene expression | 411 | 8200 |
| Liver | isoform ratio | 411 | 3616 |
| Liver | intron excision ratio | 411 | 4847 |
| Liver | mRNA stability | 411 | 3023 |
| NAcc | alternative polyA | 570 | 3530 |
| NAcc | alternative TSS | 570 | 3722 |
| NAcc | gene expression | 570 | 10176 |
| NAcc | isoform ratio | 570 | 5231 |
| NAcc | intron excision ratio | 570 | 6441 |
| NAcc | mRNA stability | 570 | 3687 |
| OFC | alternative polyA | 82 | 1177 |
| OFC | alternative TSS | 82 | 809 |
| OFC | gene expression | 82 | 4539 |
| OFC | isoform ratio | 82 | 1419 |
| OFC | intron excision ratio | 82 | 1295 |
| OFC | mRNA stability | 82 | 1330 |
| PL | alternative polyA | 404 | 3294 |
| PL | alternative TSS | 404 | 3333 |
| PL | gene expression | 404 | 9804 |
| PL | isoform ratio | 404 | 4724 |
| PL | intron excision ratio | 404 | 5582 |
| PL | mRNA stability | 404 | 3781 |
| pVTA | alternative polyA | 293 | 2571 |
| pVTA | alternative TSS | 293 | 2485 |
| pVTA | gene expression | 293 | 7859 |
| pVTA | isoform ratio | 293 | 3582 |
| pVTA | intron excision ratio | 293 | 5034 |
| pVTA | mRNA stability | 293 | 2348 |
| RMTg | alternative polyA | 92 | 623 |
| RMTg | alternative TSS | 92 | 581 |
| RMTg | gene expression | 92 | 2103 |
| RMTg | isoform ratio | 92 | 773 |
| RMTg | intron excision ratio | 92 | 883 |
| RMTg | mRNA stability | 92 | 621 |