Il11ra1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Il11ra1 0.03 0.02 3.7e-03 0.02 0.01 0.01 0.01 5.3e-03 9.1e-03 3.1e-02 1.2e-02
2 pVTA gene expression Il11ra1 0.08 0.06 3.2e-03 0.07 0.06 0.07 0.07 4.3e-04 1.0e-03 5.6e-04 7.0e-04
3 Adipose gene expression Il11ra1 0.12 0.07 5.0e-16 0.14 0.13 0.13 0.14 4.2e-15 8.1e-14 4.3e-14 5.5e-15
4 LHb gene expression Il11ra1 0.41 0.23 3.2e-06 0.18 0.14 0.15 0.18 5.3e-05 3.3e-04 2.3e-04 4.8e-05
5 OFC gene expression Il11ra1 0.16 0.12 8.7e-03 0.01 0.07 0.07 0.05 2.0e-01 8.1e-03 1.0e-02 2.6e-02
6 IL gene expression Il11ra1 0.27 0.16 8.1e-05 0.15 0.14 0.16 0.14 1.6e-04 3.2e-04 9.3e-05 2.4e-04
7 Liver gene expression Il11ra1 0.34 0.11 0.0e+00 0.31 0.38 0.38 0.38 1.3e-34 5.8e-44 2.3e-44 3.4e-44
8 Brain gene expression Il11ra1 0.04 0.03 4.7e-03 0.02 0.02 0.02 0.02 4.3e-03 5.7e-03 8.8e-03 7.3e-03
9 PL gene expression Il11ra1 0.06 0.04 3.6e-06 0.03 0.04 0.04 0.04 1.6e-04 1.3e-05 2.1e-05 2.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.81.42.21.0-1.21.4-1.50.21.41.40.6-1.2
Area under the delay curve0.90.91.4-0.80.7-1.21.10.4-1.2-1.2-0.61.1
BMI with tail1.44.47.12.0-2.22.7-2.60.52.32.50.9-2.1
BMI without tail2.85.811.13.3-3.32.9-2.72.22.02.0-0.6-1.2
Body weight1.66.912.23.4-3.53.2-3.02.12.42.4-0.5-1.6
Weight adjusted by age0.91.03.00.2-0.2-0.70.71.3-1.0-0.8-1.71.2
Bone surface0.30.61.11.0-1.10.9-0.80.90.70.5-0.5-0.2
Bone volume0.40.71.00.9-1.01.0-1.00.51.00.9-0.0-0.6
Breakpoint value in progressive ratio session2.12.33.9-0.70.6-1.61.81.3-1.6-1.8-1.52.0
Number of licking bursts4.24.97.82.8-2.72.7-2.70.82.42.20.2-1.7
Context. condit. distance diff. score0.10.10.3-0.40.3-0.20.1-0.50.10.10.3-0.2
Locomotion velocity, session 14.14.410.91.1-1.1-0.50.73.2-1.8-2.1-3.32.7
Locomotion distance, session 11.21.54.00.7-0.9-0.00.21.9-1.0-1.1-2.01.5
Locomotion velocity, session 21.72.03.21.5-1.51.8-1.80.21.61.60.5-1.3
Locomotion distance, session 21.42.04.31.9-2.11.4-1.22.00.30.3-1.60.3
Locomotion velocity, session 30.91.03.30.4-0.4-0.40.51.4-0.7-1.0-1.81.3
Locomotion distance, session 31.31.42.91.6-1.71.1-1.01.70.50.3-1.40.2
Stereotopy head waving bouts, day 30.70.81.80.20.1-0.80.91.1-0.3-0.9-1.41.3
Stereotopy head waving duration, day 30.40.41.0-0.20.5-0.91.00.4-0.1-0.6-0.60.8
Locomotion velocity, session 70.00.10.1-0.30.4-0.30.3-0.20.20.0-0.00.0
Locomotion distance, session 70.10.20.40.5-0.60.4-0.30.60.20.1-0.50.1
Stereotopy head waving bouts, day 71.51.73.82.0-1.71.4-1.31.21.51.0-0.5-0.5
Stereotopy head waving duration, day 70.50.61.51.2-1.00.7-0.50.90.90.4-0.5-0.1
Locomotion velocity, session 80.60.72.30.6-0.6-0.10.31.2-0.6-0.7-1.51.1
Locomotion distance, session 80.50.72.10.7-0.90.2-0.11.3-0.5-0.5-1.40.8
Degree of sensitization distance0.60.61.2-1.01.1-0.80.8-0.9-0.2-0.30.80.1
Degree of sensitization stereotypy0.91.02.01.4-1.31.1-1.10.71.20.9-0.1-0.5
Conditioned locomotion0.50.61.50.3-0.2-0.30.41.0-0.7-0.9-1.21.1
Cocaine response after cond. corrected2.83.25.3-1.01.0-1.81.91.1-2.1-2.3-1.82.3
Cocaine response after cond. not corrected2.93.25.7-0.80.8-1.71.91.3-2.1-2.3-2.02.4
Cocaine response before conditioning0.80.91.51.0-1.01.1-1.10.21.21.20.2-0.8
Saline control response1.01.33.41.6-1.40.7-0.51.80.3-0.1-1.50.7
Bone: connectivity density0.40.71.20.5-0.60.9-1.0-0.21.01.10.7-1.0
Bone: cortical apparent density0.91.32.7-0.30.40.5-0.6-1.61.11.21.7-1.5
Bone: cortical area1.82.63.91.6-1.72.0-2.00.21.91.90.7-1.7
Bone: cortical porosity0.30.30.6-0.70.7-0.60.6-0.5-0.7-0.60.30.2
Bone: cortical porosity0.00.00.1-0.00.00.0-0.0-0.0-0.3-0.20.10.0
Bone: cortical thickness1.21.93.50.7-0.71.4-1.5-0.81.71.81.5-1.9
Bone: cortical thickness0.30.31.0-0.60.5-0.10.1-0.80.40.41.0-0.6
Bone: cortical tissue density0.81.02.4-0.40.40.3-0.5-1.50.91.11.5-1.4
Condit. Reinf. active minus inactive responses0.40.50.70.8-0.70.8-0.80.10.80.90.1-0.7
Condit. Reinf. active-inactive response ratio0.40.40.9-0.81.0-0.70.7-0.8-0.3-0.20.6-0.0
Condit. Reinf. active responses2.22.63.81.9-1.82.0-1.90.51.91.90.1-1.4
Condit. Reinf. inactive responses2.73.24.81.9-1.92.2-2.20.32.22.20.3-1.7
Incentive salience index mean2.83.36.12.5-2.42.2-2.21.31.61.6-0.5-1.0
Condit. Reinf. lever presses6.18.116.54.0-4.13.3-3.12.92.11.9-1.6-0.8
Condit. Reinf. active minus inactive responses0.40.50.90.8-0.91.0-1.00.30.70.70.2-0.6
Condit. Reinf. active-inactive response ratio0.10.10.2-0.1-0.10.3-0.3-0.20.10.20.4-0.4
Condit. Reinf. active responses1.42.03.11.8-1.81.8-1.70.81.41.30.1-1.0
Condit. Reinf. inactive responses2.83.55.32.1-1.92.3-2.30.32.12.10.7-1.8
Condit. Reinf. lever presses2.33.15.71.3-1.31.9-1.9-0.32.42.31.3-2.1
Condit. Reinf. lever reinforcers received1.62.33.61.9-1.91.9-1.90.91.61.50.1-1.1
Conditioned reinforcement - actives0.80.81.31.1-1.01.1-1.1-0.11.10.70.5-0.7
Conditioned reinforcement - inactives0.30.41.01.0-0.80.7-0.70.10.70.2-0.1-0.1
Conditioned locomotion0.30.30.80.9-0.80.7-0.70.40.60.4-0.0-0.3
Patch foraging indifference point 0 sec2.13.49.60.8-0.9-0.70.92.7-1.6-1.8-3.12.3
Patch foraging indifference point AUC3.84.48.93.0-3.02.6-2.51.91.41.5-0.7-0.9
Delay disc. indifference point, 0s delay1.11.22.0-1.11.0-1.41.40.1-1.2-1.3-0.51.2
Delay disc. indifference point, 16s delay1.92.03.5-0.60.5-1.41.40.9-1.8-1.9-1.41.9
Delay disc. indifference point, 2s delay0.30.30.60.1-0.10.5-0.5-0.60.80.70.8-0.7
Delay disc. indifference point, 24s delay0.20.20.5-0.50.5-0.50.5-0.1-0.7-0.4-0.10.3
Delay disc. indifference point, 4s delay0.20.20.4-0.60.6-0.60.5-0.1-0.3-0.30.20.2
Delay disc. indifference point, 8s delay0.10.10.1-0.30.2-0.30.20.2-0.3-0.2-0.10.2
Indifference point function ln k1.31.93.6-1.91.9-1.81.7-1.0-0.9-1.00.10.8
Indifference point function log k1.31.93.6-1.91.9-1.81.7-1.0-0.9-1.00.10.8
Patch foraging total patch changes 0 sec1.82.88.31.2-1.2-0.20.42.7-1.2-1.4-2.91.9
Patch foraging total patch changes 12 sec1.01.32.61.6-1.61.4-1.41.00.50.7-0.4-0.5
Patch foraging total patch changes 18 sec0.40.51.40.9-0.90.3-0.21.2-0.2-0.1-1.10.4
Patch foraging total patch changes 24 sec1.21.43.01.6-1.71.1-1.01.70.20.2-1.40.2
Patch foraging total patch changes 6 sec1.82.67.12.1-2.11.0-0.82.7-0.3-0.3-2.30.9
Patch foraging time to switch 0 sec1.21.93.9-1.91.9-1.31.1-2.0-0.6-0.51.4-0.2
Patch foraging water rate 0 sec1.01.64.31.6-1.60.8-0.62.1-0.2-0.1-1.90.7
Patch foraging water rate 12 sec0.10.10.4-0.0-0.1-0.10.20.60.0-0.2-0.60.5
Patch foraging water rate 18 sec0.50.71.10.4-0.51.0-1.0-0.31.00.90.9-0.9
Patch foraging water rate 24 sec0.60.81.6-0.50.40.4-0.5-1.20.91.01.2-1.2
Patch foraging water rate 6 sec0.71.11.71.2-1.31.3-1.30.61.30.9-0.1-0.6
Seeking ratio, delayed vs. immediate footshock2.32.74.32.1-2.02.0-2.00.71.61.70.0-1.3
Distance traveled before self-admin3.94.29.53.1-3.02.2-2.02.21.31.1-1.4-0.3
Distance traveled after self-admin1.92.13.81.5-1.51.7-1.7-0.02.01.70.6-1.3
Extensor digitorum longus weight2.911.520.04.5-4.54.0-3.82.53.63.1-0.7-1.9
Bone: elastic displacement3.33.78.2-2.92.8-2.22.0-2.1-1.4-0.91.10.2
Bone: elastic work2.43.18.4-2.22.1-0.90.6-2.90.30.62.6-1.5
Bone: endosteal estimation0.71.53.11.7-1.81.1-1.01.70.80.5-1.20.3
Bone: endosteal perimeter0.81.63.91.6-1.70.9-0.82.00.60.2-1.50.6
Epididymis fat weight0.30.71.41.1-1.20.8-0.71.10.20.3-0.9-0.1
Delta time in closed arm before/after self-admin1.71.73.11.0-1.01.5-1.6-0.31.41.80.7-1.6
Delta time in open arm before/after self-admin0.40.40.9-0.20.2-0.50.60.4-0.6-0.9-0.40.9
Diff in mean of infusions in LGA sessions0.20.20.4-0.60.6-0.50.5-0.30.10.10.3-0.1
Delay discount exponential model param0.80.81.30.7-0.61.1-1.0-0.41.11.10.5-1.0
Extinction: sum of active levers before priming0.80.81.6-1.31.3-1.01.0-0.6-0.7-0.90.30.6
Active lever presses in extinction session 61.31.21.9-1.21.1-1.41.4-0.0-1.4-1.3-0.21.0
Bone: final force0.81.31.91.4-1.41.4-1.30.61.31.20.1-0.8
Bone: final moment0.71.11.81.1-1.11.2-1.20.31.31.20.4-1.0
Food consumed during 24 hour testing period0.70.81.71.3-1.31.0-0.91.20.30.2-0.90.1
Glucose0.50.81.91.1-1.41.1-1.11.00.30.5-0.3-0.3
Heart weight0.30.41.10.9-1.00.6-0.51.10.10.1-0.40.1
Delay discount hyperbolic model param0.70.71.10.7-0.61.0-1.0-0.41.11.00.5-1.0
Intermittent access intake day 1-15 change1.31.32.60.6-0.51.1-1.2-0.71.41.61.0-1.6
Intermittent access intake escalation1.11.12.20.8-0.71.2-1.3-0.31.01.50.4-1.4
Intermittent access intake escalation 22.62.64.51.1-1.01.9-2.0-0.91.82.11.1-2.0
Intermitt. access day 1 inactive lever presses0.40.51.01.0-1.00.8-0.80.70.20.4-0.6-0.2
Intermitt. access day 15 inactive lever presses0.20.30.70.6-0.60.1-0.00.8-0.2-0.3-0.80.5
Intermitt. access escalation Index0.70.61.71.1-1.10.7-0.51.30.30.1-0.70.3
Intermittent access day 1 total infusions0.91.02.4-0.40.5-1.01.10.6-1.1-1.5-0.61.4
Intermittent access day 15 total infusions0.20.30.70.8-0.70.6-0.60.40.40.4-0.1-0.3
Intermittent access terminal intake (last 3 days)0.80.92.11.5-1.31.2-1.10.60.90.7-0.2-0.4
Intermittent access total infusions0.50.61.51.2-1.10.8-0.80.80.40.2-0.4-0.0
Intermittent access day 1 locomotion1.61.63.2-1.01.1-1.51.50.3-1.5-1.8-0.41.5
Intermittent access day 15 total locomotion0.70.71.2-0.91.0-1.01.0-0.2-1.0-1.10.00.7
Intermittent access total locomotion0.30.30.8-0.80.9-0.50.5-0.7-0.2-0.40.70.1
Intermittent access standard deviation0.60.61.20.9-0.81.1-1.1-0.10.70.90.2-0.8
Left kidney weight0.41.22.91.5-1.50.8-0.61.7-0.2-0.3-1.40.6
Right kidney weight0.20.41.00.5-0.4-0.10.31.0-0.6-0.6-1.00.8
Cocaine induced anxiety0.30.30.5-0.60.6-0.50.5-0.4-0.7-0.7-0.30.5
Post-drug Anxiety0.40.41.11.0-1.00.8-0.80.60.40.3-0.3-0.1
Baseline Anxiety0.70.71.40.6-0.60.8-0.9-0.11.01.20.6-1.1
Tail length1.33.99.13.0-2.72.1-1.92.21.51.4-1.1-0.6
Length with tail0.51.74.21.9-1.81.0-0.82.00.40.3-1.60.3
Length without tail0.30.71.2-1.00.8-1.01.1-0.1-0.9-1.0-0.50.8
Times rat made contact with spout0.70.81.60.7-0.70.9-1.0-0.31.21.10.6-1.0
Lifetime Intake1.01.12.71.6-1.50.8-0.61.50.2-0.3-1.10.6
Liver weight, left0.40.71.51.2-1.21.1-1.00.60.40.5-0.3-0.4
Liver weight, right0.00.10.10.3-0.20.00.10.2-0.1-0.3-0.30.4
Locomotor activity0.00.00.10.1-0.30.3-0.30.10.10.00.3-0.1
Locomotor testing distance0.20.40.90.1-0.3-0.20.20.9-0.5-0.8-0.80.9
Locomotor testing rearing0.81.22.71.6-1.61.3-1.21.20.90.5-0.6-0.1
Locomotion in novel chamber0.10.20.6-0.40.40.0-0.2-0.80.00.40.5-0.5
Locomotion in novel chamber post-restriction2.22.74.90.9-0.91.7-1.8-0.92.12.21.4-2.1
Fecal boli incidents, locomotor time 11.11.22.5-1.61.5-1.41.2-0.8-1.1-0.70.10.3
Change in fecal boli incidents, locomotor task0.80.72.11.2-1.30.5-0.41.40.2-0.1-0.80.5
Time >=10cm from walls, locomotor time 10.40.40.90.2-0.3-0.50.61.0-0.3-0.7-0.60.8
Bouts of movement, locomotor time 10.80.92.0-1.41.4-1.00.9-1.1-0.5-0.50.50.2
Total resting periods, locomotor time 11.31.43.4-1.81.8-1.11.0-1.6-0.4-0.31.1-0.2
Rest time, locomotor task time 12.32.67.5-1.91.8-0.30.0-2.70.61.02.2-1.6
Distance moved, locomotor task time 12.02.15.62.1-2.00.9-0.72.40.2-0.2-1.80.9
Vertical activity count, locomotor time 11.71.85.61.7-1.80.4-0.32.4-0.2-0.7-1.51.4
Time >=10cm from walls, locomotor time 20.10.10.40.3-0.30.1-0.00.5-0.3-0.2-0.60.2
Bouts of movement, locomotor time 20.40.50.80.8-0.80.7-0.80.20.90.70.2-0.6
Total resting periods, locomotor time 20.20.30.60.4-0.40.5-0.6-0.10.80.60.3-0.6
Rest time, locomotor task time 20.60.61.6-1.31.3-0.70.6-1.10.10.10.6-0.3
Distance moved, locomotor task time 20.50.61.10.7-0.71.0-1.1-0.10.70.90.4-0.8
Vertical activity count, locomotor time 20.30.30.90.8-0.90.5-0.50.80.10.1-0.20.1
Light reinforcement 12.23.911.22.1-2.10.6-0.33.3-0.9-1.3-2.91.9
Light reinforcement 23.14.210.01.4-1.4-0.30.63.2-1.7-2.2-3.02.6
Bone: marrow area0.71.53.21.7-1.81.2-1.11.51.00.7-1.00.0
Bone: maximum diameter1.52.84.52.0-2.12.1-2.00.91.91.7-0.0-1.1
Bone: maximum force2.03.45.22.2-2.22.3-2.20.92.12.00.2-1.4
Bone: maximum moment1.62.84.21.8-1.92.0-2.00.52.01.90.5-1.5
Mean time between licks in bursts0.20.30.6-0.80.7-0.60.6-0.4-0.2-0.20.10.2
Mean num. licks in bursts1.62.04.1-2.01.9-1.71.7-1.1-1.2-1.10.40.7
Cd content in liver1.31.52.51.1-1.01.3-1.4-0.31.61.41.1-1.3
Co content in liver1.01.21.9-0.81.0-1.41.40.1-1.2-1.2-0.81.2
Cu content in liver0.50.71.8-1.01.1-0.50.4-1.30.30.31.0-0.4
Fe content in liver1.31.54.30.7-0.7-0.40.61.9-0.7-1.0-2.11.7
K content in liver0.80.81.6-0.50.6-1.01.00.6-1.3-1.1-0.71.1
Mg content in liver1.01.12.0-1.11.2-1.41.4-0.1-1.0-1.0-0.10.9
Mn content in liver0.50.61.20.10.10.4-0.4-0.61.11.01.1-1.1
Na content in liver0.60.61.1-1.01.1-1.00.9-0.6-0.8-0.70.20.4
Rb content in liver3.03.76.0-2.22.3-2.42.4-0.7-2.2-2.0-0.31.5
Se content in liver1.92.33.21.6-1.41.8-1.8-0.11.81.71.0-1.6
Sr content in liver0.30.30.90.6-0.40.4-0.40.10.90.70.6-0.5
Zn content in liver0.50.51.1-0.20.20.3-0.4-0.81.01.01.1-0.9
Bone: minimum diameter0.10.10.3-0.40.4-0.20.1-0.50.30.20.6-0.3
Time in familiar zone, hab. session 12.82.66.6-1.01.00.2-0.4-2.41.51.62.6-2.0
Time in novel zone, hab. session 13.53.46.9-0.70.8-1.82.01.5-1.9-2.2-2.32.6
Total zone transitions, hab. session 10.00.00.1-0.2-0.10.1-0.1-0.0-0.3-0.1-0.10.0
Total locomotion distance, hab. session 10.71.12.30.1-0.41.0-1.1-0.90.91.21.2-1.5
Locomotion velocity, hab. session 11.31.83.31.0-1.31.7-1.8-0.31.11.50.9-1.7
Time in familiar zone, hab. session 21.21.23.3-1.31.1-0.30.1-1.80.60.71.8-1.1
Time in novel zone, hab. session 22.32.34.3-0.50.8-1.61.71.0-1.6-1.8-1.72.1
Total zone transitions, hab. session 20.70.92.61.0-1.00.5-0.41.4-0.6-0.4-1.60.7
Total locomotion distance, hab. session 20.50.61.21.0-1.11.1-1.00.60.30.6-0.6-0.4
Locomotion velocity, hab. session 20.60.81.61.1-1.21.3-1.20.60.30.6-0.5-0.5
Novel to familiar place preference ratio3.53.65.6-1.61.6-2.32.40.3-2.1-2.3-1.32.2
Novelty place preference4.24.36.8-2.02.0-2.52.60.0-2.4-2.4-1.02.1
Time in novel zone, NPP test4.95.08.2-2.12.2-2.82.9-0.0-2.5-2.6-1.12.3
Total zone transitions, NPP test0.81.13.01.0-1.30.5-0.41.7-0.5-0.4-1.70.8
Total locomotion distance, NPP test1.11.63.31.6-1.81.1-1.01.8-0.2-0.1-1.60.3
Locomotion velocity, NPP test1.31.84.11.7-2.01.5-1.31.7-0.10.2-1.4-0.0
Intraocular pressure1.41.95.22.3-2.01.4-1.21.71.00.6-0.7-0.0
Delta distance traveled before/after self-admin0.20.20.7-0.50.4-0.10.0-0.80.20.10.7-0.3
Delta ambulatory time before/after self-admin0.50.51.5-1.11.0-0.50.4-1.2-0.1-0.10.7-0.2
Parametrial fat weight0.20.30.90.8-0.60.2-0.20.9-0.4-0.2-0.70.4
Pavlov. Cond. lever latency4.96.211.7-3.43.3-3.02.8-2.0-2.3-2.10.91.1
Pavlov. Cond. magazine entry latency0.30.41.00.5-0.60.7-0.70.21.00.90.1-0.5
Pavlov. Cond. change in total contacts1.81.93.71.9-1.91.6-1.61.31.11.1-0.7-0.5
Pavlov. Cond. index score2.22.84.42.1-2.12.0-2.00.91.91.8-0.2-1.1
Pavlov. Cond. latency score2.12.64.12.0-2.01.9-1.91.01.81.7-0.2-1.0
Pavlov. Cond. lever contacts3.54.27.52.7-2.62.4-2.31.52.12.0-0.6-1.0
Pavlov. Cond. magazine entry number0.60.71.2-0.90.9-1.01.0-0.3-1.1-1.10.00.7
Pavlov. Cond. intertrial magazine entries0.20.30.40.6-0.50.6-0.70.00.50.60.2-0.5
Pavlov. Cond. lever-magazine prob. diff.2.22.74.01.9-1.82.0-1.90.62.01.90.1-1.3
Pavlov. Cond. response bias2.12.64.02.0-2.01.9-1.81.01.81.7-0.4-0.9
Pavlov. Cond. lever latency3.44.610.5-1.51.5-2.22.20.5-3.2-2.9-1.52.3
Pavlov. Cond. magazine entry latency0.30.40.7-0.70.6-0.30.3-0.80.90.50.7-0.4
Pavlov. Cond. change in total contacts2.43.47.20.2-0.41.4-1.5-1.42.72.62.2-2.4
Pavlov. Cond. index score1.41.84.80.1-0.10.8-0.9-1.12.21.91.5-1.6
Pavlov. Cond. latency score1.72.15.70.2-0.20.9-1.1-1.22.42.11.6-1.8
Pavlov. Cond. lever contacts1.72.36.01.0-1.01.4-1.5-0.32.52.11.1-1.6
Pavlov. Cond. magazine entry number1.51.84.20.2-0.1-0.60.71.4-2.1-1.8-1.81.6
Pavlov. Cond. intertrial magazine entries0.30.40.70.8-0.80.5-0.50.8-0.6-0.4-0.50.2
Pavlov. Cond. lever-magazine prob. diff.1.41.84.9-0.0-0.10.8-0.9-1.22.21.91.6-1.6
Pavlov. Cond. response bias1.31.84.90.5-0.51.1-1.1-0.72.21.91.3-1.6
Time in closed arm before self-admin1.92.13.4-1.81.8-1.71.7-0.9-1.6-1.50.40.9
Time in closed arm after self-admin0.20.20.6-0.60.6-0.30.2-0.7-0.40.00.4-0.3
Time in open arm before self-admin1.51.63.41.9-1.81.0-0.81.80.60.4-1.50.2
Time in open arm after self-admin1.01.12.31.5-1.50.9-0.81.50.40.1-1.10.4
Bone: periosteal estimation1.02.03.71.8-1.91.7-1.61.11.51.2-0.4-0.6
Bone: periosteal perimeter0.40.71.71.0-1.10.6-0.51.30.30.1-1.10.4
Bone: post-yield work1.01.43.01.5-1.71.3-1.11.50.70.5-1.10.1
Progressive ratio test 1 active lever presses0.60.61.51.2-1.20.6-0.51.10.3-0.4-0.60.7
Progressive ratio test 1 breakpoint0.70.81.91.4-1.30.7-0.61.20.4-0.3-0.70.6
Progressive ratio test 1 inactive lever presses1.51.74.31.7-1.60.5-0.32.1-0.2-0.9-1.61.4
Progressive ratio test 2 active lever presses0.70.81.51.1-1.00.10.01.2-0.3-0.9-1.01.1
Progressive ratio test 2 breakpoint0.50.61.30.7-0.6-0.10.31.0-0.4-1.0-0.81.2
Progressive ratio test 2 inactive lever presses0.50.51.41.2-1.10.8-0.70.80.40.1-0.50.1
Incentive Sensitization - Responses0.40.41.21.1-1.00.3-0.30.70.1-0.2-0.60.5
Incentive Sensitization - Breakpoint0.30.30.80.9-0.80.2-0.20.60.0-0.3-0.50.5
Sum of active levers in priming session hrs 5-63.93.75.9-1.91.9-2.42.4-0.0-2.3-2.2-0.91.9
Progressive ratio0.20.20.6-0.10.1-0.40.30.2-0.8-0.5-0.60.5
Food seeking constrained by brief footshock5.66.916.34.0-4.02.9-2.53.01.30.9-1.80.1
Seeking ratio, punishment vs. effort1.82.24.62.1-2.11.8-1.71.21.51.0-0.4-0.5
Retroperitoneal fat weight0.10.40.8-0.90.9-0.70.6-0.7-0.20.00.5-0.2
Reaction time number correct0.20.30.70.2-0.3-0.00.10.8-0.4-0.6-0.70.7
Reaction time mean minus median2.73.57.0-0.1-0.01.3-1.5-2.02.22.32.6-2.6
Reaction time mean minus median AUC2.33.05.20.5-0.61.6-1.8-1.32.22.22.1-2.3
Reaction time num false alarms0.40.51.3-0.00.20.3-0.4-0.81.00.81.2-0.9
Reaction time num false alarms AUC0.30.51.10.6-0.50.7-0.7-0.01.10.80.6-0.7
Reaction time trials correct on left0.20.30.70.2-0.3-0.00.10.8-0.4-0.6-0.70.7
Reaction time trials on left0.20.20.50.0-0.2-0.10.20.7-0.5-0.6-0.70.7
Reaction time mean1.52.16.0-1.71.6-0.50.3-2.40.81.02.0-1.4
Reaction time mean AUC1.82.56.9-1.81.7-0.50.3-2.60.91.12.2-1.4
Median of all reaction times1.52.04.6-2.12.1-1.31.2-2.1-0.10.11.2-0.4
Reaction time omissions0.91.22.9-1.71.7-1.41.3-1.1-0.2-0.20.50.2
Reaction time false alarm rate0.30.41.1-0.10.30.2-0.2-0.80.90.71.1-0.9
Reaction time premature initiation rate1.72.34.8-2.22.2-1.71.5-1.8-0.7-0.41.4-0.2
Reaction time premature initiations1.11.63.5-1.91.8-1.51.4-1.2-0.8-0.60.90.1
Std. dev. reaction times2.02.97.0-0.90.80.5-0.7-2.41.61.92.6-2.2
Reaction time trials completed0.20.20.50.0-0.2-0.10.20.7-0.5-0.6-0.70.7
Reaction time trials AUC0.20.20.50.0-0.2-0.20.20.7-0.5-0.6-0.60.7
Run reversals in cocaine runway, females0.20.20.6-0.40.30.2-0.2-0.70.10.40.6-0.6
Run reversals in cocaine runway, males0.00.00.1-0.10.1-0.00.0-0.30.20.10.3-0.2
Latency to leave start box in cocaine runway0.60.61.10.9-0.80.9-0.90.10.91.1-0.0-0.8
Latency to leave start box in cocaine runway, F0.20.20.5-0.10.2-0.50.50.3-0.5-0.3-0.70.3
Latency to leave start box in cocaine runway, M1.31.22.51.6-1.61.2-1.11.01.10.8-0.5-0.3
Std. dev. time between licks in bursts0.20.30.6-0.70.8-0.60.6-0.6-0.4-0.30.40.1
Total sessions with >9 infusions1.11.22.61.0-0.9-0.20.31.6-0.5-1.2-1.31.5
Short access day 1 total inactive lever presses2.22.55.82.4-2.41.7-1.61.80.60.4-1.30.1
Short access day 10 total inactive lever presses0.40.40.90.7-0.70.9-0.90.30.30.6-0.4-0.4
Short access day 1 total infusions2.42.55.52.3-2.31.2-1.02.30.4-0.4-1.71.0
Short access day 10 total infusions1.01.13.21.1-1.10.10.01.8-0.5-0.9-1.41.2
Short access total infusions1.31.53.61.6-1.50.5-0.31.9-0.2-1.0-1.51.3
Short access day 1 locomotion0.60.61.4-0.20.3-0.60.70.8-1.0-1.2-0.71.2
Short access day 10 total locomotion0.50.61.2-1.11.1-0.50.4-1.1-0.4-0.40.9-0.2
Short access total locomotion0.20.30.70.2-0.2-0.10.20.8-0.4-0.8-0.30.8
One hour access (0.3 mA shock)0.50.51.21.1-1.00.3-0.21.1-0.1-0.4-1.00.6
Compulsive drug intake0.10.10.20.3-0.4-0.10.10.4-0.3-0.1-0.50.2
One hour access (shock baseline)0.60.71.51.0-0.90.3-0.21.2-0.3-0.5-1.20.8
Social response proportion1.41.52.8-1.71.6-1.31.1-1.3-1.5-0.80.50.1
Social responses0.30.40.80.8-0.90.9-0.80.50.30.5-0.2-0.3
Social time0.10.20.7-0.20.1-0.30.30.2-0.5-0.2-0.80.4
Soleus weight1.13.37.90.2-0.3-1.01.32.4-1.7-2.0-2.82.5
Bone: stiffness2.74.36.62.5-2.52.6-2.51.02.22.10.2-1.6
Tibialis anterior weight4.515.330.25.3-5.54.6-4.33.63.63.0-1.8-1.4
Time to tail flick, vehicle, before self-admin1.51.53.5-1.91.9-1.41.3-0.9-1.2-0.90.20.5
Time to tail flick, vehicle, after self-admin0.00.00.10.2-0.20.1-0.00.20.0-0.1-0.10.2
Time to tail flick, test, before self-admin0.60.50.80.8-0.70.9-0.9-0.20.90.80.4-0.7
Time to tail flick, test, after self-admin0.50.51.10.1-0.10.6-0.7-0.60.60.90.9-1.0
Delta time to tail flick, vehicle, before/after SA0.50.51.21.1-1.00.7-0.70.50.60.4-0.2-0.2
Delta time to tail flick, test, before/after SA0.20.20.5-0.70.6-0.50.5-0.3-0.5-0.20.20.0
Tibia length0.41.33.10.3-0.5-0.50.61.7-0.9-1.2-1.81.5
Ambulatory time before self-admin2.82.96.72.6-2.61.5-1.42.30.70.5-1.60.3
Ambulatory time after self-admin0.40.40.90.9-0.90.7-0.70.50.70.5-0.4-0.2
Bone: tissue strength0.10.10.30.2-0.40.5-0.5-0.00.40.50.1-0.5
Total heroin consumption0.60.71.6-0.30.3-0.80.90.8-0.7-1.2-0.61.3
Bone: trabecular number0.91.52.30.9-1.01.5-1.5-0.11.41.50.9-1.4
Bone: trabecular spacing0.20.20.50.10.00.3-0.3-0.70.50.50.7-0.7
Bone: trabecular thickness0.10.20.4-0.70.5-0.30.3-0.50.30.20.4-0.1
Bone: trabecular tissue density2.33.25.52.3-2.32.3-2.21.01.91.6-0.0-1.0
Water consumed over 24 hours0.80.91.61.3-1.21.2-1.10.41.00.9-0.1-0.6
Number of responses in last shaping day2.22.35.71.0-1.1-0.20.42.4-1.2-1.5-2.31.9