Hub : Genes

Il11ra1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Il11ra1 0.15 0.08 3.6e-10 0.13 0.14 0.14 0.14 1.6e-10 3.3e-11 2.8e-11 2.4e-11
2 NAcc gene expression Il11ra1 0.02 0.02 3.4e-03 0.02 0.02 0.01 -0 1.3e-03 1.3e-03 2.2e-03 7.9e-01
3 Adipose mRNA stability Il11ra1 0.03 0.02 4.0e-03 0.01 0.01 0.01 0.01 7.7e-03 1.4e-02 9.3e-03 2.0e-02
4 IC gene expression Il11ra1 0.2 0.12 5.1e-05 0.1 0.09 0.08 0.09 3.6e-05 2.0e-04 2.4e-04 1.0e-04
5 Adipose gene expression Il11ra1 0.12 0.06 3.9e-16 0.14 0.13 0.13 0.14 3.0e-15 5.3e-14 6.7e-14 3.9e-15
6 Liver gene expression Il11ra1 0.34 0.11 0.0e+00 0.32 0.38 0.39 0.38 5.2e-36 1.6e-44 1.2e-45 6.4e-45
7 IL gene expression Il11ra1 0.24 0.15 2.5e-04 0.1 0.12 0.14 0.1 1.9e-03 6.8e-04 3.0e-04 2.2e-03
8 PL gene expression Il11ra1 0.05 0.04 4.6e-05 0.03 0.03 0.03 0.03 5.7e-04 1.4e-04 4.7e-04 4.5e-04
9 Brain gene expression Il11ra1 0.04 0.03 6.2e-03 0.02 0.02 0.02 0.02 3.8e-03 3.8e-03 6.0e-03 3.9e-03
10 LHb gene expression Il11ra1 0.55 0.5 1.6e-06 0.16 0.13 0.15 0.19 9.9e-05 5.0e-04 2.5e-04 2.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.42.33.21.1-1.8-1.0-1.7-1.7-1.7-1.8-1.7-1.3-1.3
Area under the delay curve0.91.01.5-0.91.20.91.01.21.11.11.10.90.7
BMI with tail1.13.96.92.1-2.6-2.0-2.4-2.2-2.0-2.1-1.7-1.0-0.9
BMI without tail1.44.48.22.3-2.9-2.4-2.6-2.3-2.0-2.1-1.6-0.8-0.6
Body weight1.67.014.23.7-3.4-3.8-3.4-3.0-1.9-2.2-1.10.30.5
Weight adjusted by age0.30.41.50.7-0.2-0.3-0.10.30.40.60.60.91.2
Bone surface0.50.91.61.1-1.3-1.0-1.2-1.1-0.9-0.9-0.7-0.3-0.2
Bone volume0.61.01.60.9-1.3-0.8-1.2-1.1-1.1-1.2-1.0-0.7-0.7
Breakpoint value in progressive ratio session4.45.39.4-0.42.00.72.02.22.82.53.03.12.6
Number of licking bursts3.45.57.72.7-2.7-2.7-2.8-2.8-2.4-2.5-2.0-1.1-0.8
Context. condit. distance diff. score0.00.10.2-0.40.20.30.20.10.10.0-0.1-0.3-0.4
Locomotion velocity, session 13.63.910.90.80.3-1.10.50.42.11.92.73.23.3
Locomotion distance, session 10.91.13.40.5-0.1-0.7-0.00.11.00.91.41.71.8
Locomotion velocity, session 21.92.23.51.3-1.9-1.3-1.8-1.6-1.6-1.6-1.4-1.0-0.8
Locomotion distance, session 21.11.53.41.8-1.5-1.8-1.4-1.3-0.4-0.60.10.81.0
Locomotion velocity, session 30.70.82.20.50.2-0.60.30.10.90.81.21.51.4
Locomotion distance, session 31.01.12.51.5-1.2-1.6-1.3-1.0-0.2-0.40.20.80.8
Stereotopy head waving bouts, day 30.80.92.10.60.7-0.20.80.61.00.91.21.41.3
Stereotopy head waving duration, day 30.30.40.80.20.70.10.90.50.60.50.70.70.6
Locomotion velocity, session 70.00.00.1-0.20.20.30.30.30.20.20.10.10.0
Locomotion distance, session 70.10.10.40.6-0.4-0.5-0.3-0.20.1-0.00.20.50.5
Stereotopy head waving bouts, day 70.70.82.31.5-0.9-1.5-0.9-1.1-0.4-0.7-0.10.40.3
Stereotopy head waving duration, day 70.40.51.51.2-0.7-1.2-0.6-0.9-0.4-0.6-0.20.20.0
Locomotion velocity, session 80.60.71.80.20.1-0.60.30.10.90.81.11.31.3
Locomotion distance, session 80.30.41.20.5-0.3-0.7-0.1-0.20.50.40.81.11.1
Degree of sensitization distance0.50.51.2-0.91.01.11.00.90.40.50.2-0.2-0.2
Degree of sensitization stereotypy1.01.02.01.3-1.2-1.4-1.2-1.3-0.9-1.0-0.6-0.2-0.3
Conditioned locomotion0.50.61.70.10.6-0.20.30.40.80.81.01.11.3
Cocaine response after cond. corrected2.83.44.9-0.81.91.01.91.82.22.02.22.02.0
Cocaine response after cond. not corrected2.93.45.2-0.61.70.91.71.72.22.12.32.22.2
Cocaine response before conditioning0.70.81.31.0-1.1-1.0-1.1-1.1-1.0-0.9-0.8-0.5-0.3
Saline control response0.70.92.61.6-0.6-1.6-0.6-0.80.0-0.20.51.21.1
Bone: connectivity density0.81.31.90.5-1.2-0.4-1.2-1.1-1.3-1.3-1.4-1.3-1.3
Bone: cortical apparent density0.71.02.4-0.3-0.70.1-0.6-0.6-1.1-0.9-1.3-1.5-1.4
Bone: cortical area3.14.86.51.8-2.5-1.7-2.5-2.2-2.5-2.5-2.4-1.8-1.6
Bone: cortical porosity0.10.10.3-0.40.50.60.50.40.10.1-0.0-0.2-0.3
Bone: cortical porosity0.00.00.00.20.2-0.00.10.0-0.0-0.10.00.10.0
Bone: cortical thickness2.23.65.80.9-1.9-0.8-1.8-1.6-2.3-2.2-2.4-2.2-2.1
Bone: cortical thickness0.40.51.5-0.6-0.10.7-0.00.2-0.6-0.5-0.9-1.1-1.2
Bone: cortical tissue density0.50.71.9-0.3-0.60.1-0.5-0.5-1.0-0.8-1.2-1.4-1.3
Condit. Reinf. active minus inactive responses0.50.50.90.8-0.9-0.7-0.9-0.8-0.8-0.7-0.7-0.4-0.2
Condit. Reinf. active-inactive response ratio0.30.30.9-0.90.60.90.70.60.30.50.1-0.2-0.2
Condit. Reinf. active responses2.32.84.71.9-2.1-1.8-2.2-1.9-1.8-1.7-1.5-0.8-0.5
Condit. Reinf. inactive responses3.03.65.62.0-2.4-1.8-2.4-2.0-2.1-2.0-1.8-1.2-0.9
Incentive salience index mean2.83.56.12.5-2.3-2.4-2.4-2.2-1.7-1.7-1.1-0.30.1
Condit. Reinf. lever presses5.98.317.14.1-3.5-4.1-3.6-3.5-2.1-2.3-1.10.40.8
Condit. Reinf. active minus inactive responses0.60.81.20.6-1.1-0.8-1.1-1.1-0.9-1.0-0.9-0.6-0.6
Condit. Reinf. active-inactive response ratio0.20.20.5-0.2-0.5-0.1-0.5-0.3-0.4-0.5-0.5-0.6-0.7
Condit. Reinf. active responses1.62.23.81.5-1.8-1.6-1.9-1.8-1.5-1.6-1.2-0.6-0.6
Condit. Reinf. inactive responses3.03.85.32.0-2.1-1.8-2.3-2.3-2.2-2.2-1.9-1.3-1.1
Condit. Reinf. lever presses3.54.86.51.8-2.3-1.7-2.4-2.3-2.5-2.5-2.4-1.9-1.8
Condit. Reinf. lever reinforcers received1.92.64.41.7-2.0-1.8-2.1-2.0-1.6-1.7-1.3-0.7-0.6
Conditioned reinforcement - actives0.10.30.70.90.7-0.70.3-0.4-0.2-0.7-0.00.2-0.4
Conditioned reinforcement - inactives0.20.20.90.71.0-0.30.7-0.20.3-0.10.40.50.1
Conditioned locomotion0.10.20.50.60.5-0.40.10.30.4-0.10.50.70.2
Patch foraging indifference point 0 sec1.42.67.30.90.5-0.70.40.51.71.52.12.62.7
Patch foraging indifference point AUC3.55.19.22.9-3.0-3.0-3.0-2.7-1.7-2.0-1.10.00.2
Delay disc. indifference point, 0s delay1.21.42.2-0.81.50.91.31.31.31.31.21.00.8
Delay disc. indifference point, 16s delay2.12.33.4-0.81.60.71.51.51.81.71.81.61.5
Delay disc. indifference point, 2s delay0.30.30.60.2-0.2-0.1-0.4-0.5-0.8-0.8-0.7-0.7-0.8
Delay disc. indifference point, 24s delay0.10.20.5-0.70.30.60.20.50.40.40.20.00.1
Delay disc. indifference point, 4s delay0.20.20.5-0.50.50.60.30.70.40.30.30.20.1
Delay disc. indifference point, 8s delay0.00.00.1-0.3-0.00.2-0.10.20.10.10.10.00.0
Indifference point function ln k1.22.03.8-1.71.91.71.81.71.21.40.90.30.2
Indifference point function log k1.22.03.8-1.71.91.71.81.71.21.40.90.30.2
Patch foraging total patch changes 0 sec1.12.06.01.30.1-1.1-0.00.11.31.11.72.32.4
Patch foraging total patch changes 12 sec1.01.32.31.4-1.4-1.5-1.4-1.4-0.9-1.0-0.6-0.00.1
Patch foraging total patch changes 18 sec0.20.30.70.7-0.7-0.9-0.6-0.50.0-0.00.20.60.7
Patch foraging total patch changes 24 sec0.71.23.01.6-1.1-1.7-1.4-1.2-0.5-0.6-0.00.60.9
Patch foraging total patch changes 6 sec1.21.94.72.2-1.1-2.0-1.2-1.10.1-0.10.71.51.8
Patch foraging time to switch 0 sec0.81.74.5-2.11.61.91.61.40.50.70.0-0.7-1.0
Patch foraging water rate 0 sec0.61.33.31.8-1.2-1.6-1.1-0.9-0.1-0.20.41.11.4
Patch foraging water rate 12 sec0.10.10.30.40.1-0.10.00.10.30.30.40.60.5
Patch foraging water rate 18 sec0.71.11.70.6-0.8-0.6-1.0-1.2-1.2-1.3-1.2-1.1-1.3
Patch foraging water rate 24 sec0.50.71.9-0.3-0.30.3-0.3-0.4-1.0-0.8-1.2-1.4-1.3
Patch foraging water rate 6 sec0.81.22.51.6-1.0-1.4-1.2-1.4-1.0-1.1-0.8-0.3-0.3
Seeking ratio, delayed vs. immediate footshock2.42.95.11.9-2.1-2.1-2.3-2.0-1.6-1.6-1.3-0.6-0.2
Distance traveled before self-admin2.53.39.53.1-2.0-2.8-1.9-2.0-1.2-1.3-0.50.60.7
Distance traveled after self-admin2.93.64.92.1-1.8-2.0-1.9-2.2-2.2-2.2-1.9-1.2-1.1
Extensor digitorum longus weight3.312.924.04.9-4.4-4.6-4.3-4.2-3.2-3.5-2.2-0.5-0.2
Bone: elastic displacement3.54.09.6-3.02.23.12.22.51.31.70.6-0.6-0.5
Bone: elastic work1.82.45.6-2.10.62.10.81.0-0.6-0.3-1.4-2.3-2.4
Bone: endosteal estimation0.61.33.51.8-1.2-1.9-1.3-1.1-0.5-0.50.00.80.9
Bone: endosteal perimeter0.61.23.01.7-1.1-1.7-1.2-0.9-0.2-0.40.31.01.1
Epididymis fat weight0.20.82.00.7-1.4-0.7-1.2-0.8-1.0-0.9-0.9-0.6-0.3
Delta time in closed arm before/after self-admin1.01.01.60.1-1.2-0.2-1.1-0.9-1.2-0.9-1.3-1.2-0.9
Delta time in open arm before/after self-admin0.60.60.9-0.20.90.10.90.60.90.71.00.90.7
Diff in mean of infusions in LGA sessions0.20.30.8-0.30.00.5-0.00.1-0.6-0.5-0.7-0.8-0.9
Delay discount exponential model param0.80.91.40.8-1.1-0.8-0.9-1.2-1.1-1.0-1.0-0.8-0.7
Extinction: sum of active levers before priming2.32.64.9-1.42.21.72.21.71.61.51.40.90.5
Active lever presses in extinction session 60.50.50.8-0.80.70.80.70.90.80.70.60.40.1
Bone: final force1.62.63.81.8-1.9-1.6-1.9-1.8-1.6-1.8-1.4-0.8-0.7
Bone: final moment1.52.43.41.6-1.8-1.4-1.8-1.7-1.7-1.8-1.5-1.0-1.0
Food consumed during 24 hour testing period0.50.71.71.2-1.0-1.3-1.0-1.0-0.4-0.5-0.10.40.6
Glucose1.21.94.11.7-2.0-1.9-1.9-1.6-1.0-1.1-0.70.00.2
Heart weight0.30.41.30.7-1.1-0.6-1.0-0.5-0.6-0.6-0.5-0.2-0.1
Delay discount hyperbolic model param0.60.71.00.7-0.9-0.7-0.7-1.0-1.0-0.9-0.9-0.8-0.7
Intermittent access intake day 1-15 change0.71.32.21.3-1.3-1.0-1.5-1.2-1.3-1.2-1.1-0.8-0.4
Intermittent access intake escalation0.71.42.11.1-1.3-0.9-1.4-1.2-1.4-1.3-1.3-1.0-0.7
Intermittent access intake escalation 23.13.55.01.4-1.7-1.2-2.1-2.1-2.2-2.2-2.1-1.8-1.5
Intermitt. access day 1 inactive lever presses0.20.72.11.0-1.5-1.1-1.3-0.8-0.4-0.3-0.10.30.6
Intermitt. access day 15 inactive lever presses0.10.10.70.8-0.4-0.4-0.3-0.3-0.2-0.3-0.00.20.2
Intermitt. access escalation Index0.10.20.50.5-0.7-0.6-0.5-0.4-0.2-0.3-0.00.30.1
Intermittent access day 1 total infusions2.03.26.1-1.22.51.12.51.72.11.62.01.60.7
Intermittent access day 15 total infusions0.10.10.30.50.2-0.30.2-0.2-0.3-0.6-0.2-0.1-0.6
Intermittent access terminal intake (last 3 days)0.30.41.51.20.3-1.0-0.1-0.8-0.5-0.9-0.30.1-0.4
Intermittent access total infusions0.20.20.50.70.7-0.60.6-0.20.2-0.20.40.60.1
Intermittent access day 1 locomotion2.22.94.9-1.32.11.22.21.82.01.71.81.50.7
Intermittent access day 15 total locomotion1.01.93.3-1.11.71.11.81.51.61.41.41.10.5
Intermittent access total locomotion1.01.23.0-1.11.71.21.71.10.90.60.70.2-0.4
Intermittent access standard deviation0.20.40.90.9-0.6-0.9-0.7-0.7-0.3-0.5-0.10.20.2
Left kidney weight0.31.64.22.1-1.2-1.8-1.0-0.90.10.10.61.31.8
Right kidney weight0.20.82.31.5-1.4-1.1-1.0-0.7-0.5-0.4-0.20.30.6
Cocaine induced anxiety0.10.10.30.40.3-0.40.3-0.6-0.2-0.2-0.1-0.10.2
Post-drug Anxiety0.60.72.21.3-0.5-1.5-0.5-1.2-0.4-0.5-0.10.40.6
Baseline Anxiety0.40.51.10.6-1.0-0.8-0.9-0.7-0.7-0.7-0.6-0.3-0.4
Tail length1.14.37.92.7-2.6-2.8-2.6-2.5-1.8-1.9-1.3-0.3-0.0
Length with tail0.73.07.92.7-1.8-2.8-1.9-1.7-0.5-0.70.21.31.5
Length without tail0.31.02.70.60.4-0.60.30.31.00.91.31.71.6
Times rat made contact with spout0.70.81.00.8-0.9-0.8-0.8-1.0-1.0-1.0-1.0-0.8-0.7
Lifetime Intake0.50.61.30.91.0-0.80.8-0.10.60.00.81.10.5
Liver weight, left0.10.20.50.20.20.20.30.50.50.50.60.60.7
Liver weight, right0.20.41.0-0.91.00.71.00.40.20.2-0.0-0.4-0.6
Locomotor activity0.00.00.10.0-0.1-0.0-0.0-0.1-0.1-0.2-0.1-0.1-0.4
Locomotor testing distance0.30.61.1-0.20.80.20.80.50.90.81.01.00.8
Locomotor testing rearing0.40.92.11.4-0.7-1.4-1.0-1.3-0.6-0.8-0.30.30.2
Locomotion in novel chamber0.10.20.4-0.60.30.60.30.1-0.2-0.1-0.3-0.7-0.5
Locomotion in novel chamber post-restriction1.93.04.81.2-1.7-0.9-1.6-1.7-2.2-2.1-2.1-1.9-1.5
Fecal boli incidents, locomotor time 10.60.92.5-1.50.71.61.01.30.70.90.3-0.20.0
Change in fecal boli incidents, locomotor task0.30.30.80.8-0.3-0.9-0.5-0.30.10.00.40.80.7
Time >=10cm from walls, locomotor time 10.40.41.30.50.2-0.30.20.60.80.50.91.10.8
Bouts of movement, locomotor time 10.80.92.3-1.01.51.51.21.00.50.70.3-0.1-0.1
Total resting periods, locomotor time 11.01.23.5-1.41.51.91.31.10.40.60.1-0.5-0.6
Rest time, locomotor task time 11.41.84.6-1.50.51.80.20.2-0.9-0.6-1.5-2.1-2.0
Distance moved, locomotor task time 11.01.54.21.8-0.9-2.1-0.6-0.70.30.00.91.71.6
Vertical activity count, locomotor time 10.71.74.71.5-0.2-1.60.1-0.10.90.51.52.22.0
Time >=10cm from walls, locomotor time 20.10.10.40.5-0.3-0.3-0.10.10.30.20.30.50.6
Bouts of movement, locomotor time 20.30.40.91.0-0.6-0.9-0.6-0.8-0.7-0.7-0.4-0.1-0.1
Total resting periods, locomotor time 20.10.20.40.6-0.3-0.5-0.3-0.5-0.5-0.5-0.4-0.2-0.2
Rest time, locomotor task time 20.40.61.8-0.81.01.30.80.7-0.10.1-0.2-0.6-0.8
Distance moved, locomotor task time 20.70.81.50.6-1.2-0.8-1.1-1.1-0.9-0.9-0.9-0.7-0.5
Vertical activity count, locomotor time 20.30.40.90.9-0.9-0.9-0.6-0.5-0.1-0.10.20.50.7
Light reinforcement 11.22.98.01.9-0.3-1.9-0.4-0.41.30.81.92.82.7
Light reinforcement 22.23.49.81.20.9-1.20.60.42.01.52.53.12.7
Bone: marrow area0.71.43.51.8-1.4-1.9-1.4-1.3-0.7-0.7-0.20.50.6
Bone: maximum diameter2.13.85.92.1-2.4-2.1-2.4-2.1-2.1-2.1-1.8-1.0-0.8
Bone: maximum force2.95.27.72.7-2.8-2.4-2.7-2.6-2.4-2.5-2.0-1.1-0.9
Bone: maximum moment2.74.76.62.4-2.6-2.0-2.5-2.4-2.3-2.4-2.0-1.3-1.1
Mean time between licks in bursts0.10.30.7-0.80.60.80.60.70.50.60.30.00.0
Mean num. licks in bursts1.42.13.6-1.91.81.91.81.71.31.40.90.20.0
Cd content in liver0.60.71.41.2-0.9-1.2-0.9-1.0-0.7-0.9-0.50.0-0.2
Co content in liver0.91.01.6-0.41.00.51.00.81.21.21.31.21.2
Cu content in liver0.81.02.4-1.31.21.51.21.20.60.80.3-0.2-0.2
Fe content in liver1.21.52.3-0.61.30.31.30.91.51.51.51.31.3
K content in liver0.70.71.1-0.20.80.20.80.81.00.91.01.01.0
Mg content in liver1.01.01.6-1.01.21.01.21.31.11.10.90.60.5
Mn content in liver1.71.92.81.3-1.4-0.8-1.4-1.2-1.7-1.7-1.5-1.2-1.2
Na content in liver0.60.61.3-1.11.11.11.10.80.60.60.4-0.0-0.1
Rb content in liver3.54.16.5-2.42.62.12.62.22.02.21.70.90.8
Se content in liver2.63.14.21.9-1.9-1.7-1.9-2.0-2.0-2.0-1.7-1.1-1.1
Sr content in liver0.10.10.40.6-0.40.0-0.40.0-0.2-0.4-0.20.1-0.3
Zn content in liver0.10.10.2-0.1-0.40.1-0.4-0.1-0.3-0.4-0.4-0.4-0.4
Bone: minimum diameter0.10.10.4-0.4-0.00.3-0.10.1-0.3-0.2-0.4-0.6-0.7
Time in familiar zone, hab. session 12.12.06.1-0.9-0.30.9-0.2-0.2-1.4-1.2-1.9-2.4-2.5
Time in novel zone, hab. session 14.54.57.1-0.81.90.81.81.92.52.52.72.52.6
Total zone transitions, hab. session 10.00.00.1-0.3-0.20.3-0.10.10.10.1-0.0-0.10.0
Total locomotion distance, hab. session 11.01.42.40.2-1.1-0.1-1.1-0.9-1.4-1.3-1.6-1.6-1.5
Locomotion velocity, hab. session 11.82.53.41.0-1.8-1.0-1.8-1.6-1.8-1.9-1.8-1.5-1.4
Time in familiar zone, hab. session 20.90.92.4-1.20.21.20.30.4-0.6-0.4-1.0-1.5-1.6
Time in novel zone, hab. session 22.72.74.3-0.51.70.51.61.41.91.92.12.01.9
Total zone transitions, hab. session 20.40.51.60.8-0.6-1.0-0.6-0.40.30.30.61.01.3
Total locomotion distance, hab. session 20.50.61.20.8-1.1-1.0-1.1-0.9-0.7-0.7-0.5-0.10.1
Locomotion velocity, hab. session 20.60.81.70.9-1.3-1.1-1.2-1.1-0.9-0.9-0.6-0.3-0.0
Novel to familiar place preference ratio4.04.46.0-1.52.51.72.32.42.32.42.21.71.7
Novelty place preference4.75.07.3-1.82.72.12.62.62.42.52.21.61.5
Time in novel zone, NPP test5.66.08.8-2.03.02.22.82.82.72.72.41.71.7
Total zone transitions, NPP test0.40.61.70.8-0.7-1.0-0.6-0.50.30.20.71.21.3
Total locomotion distance, NPP test0.81.12.51.4-1.3-1.6-1.3-1.0-0.2-0.40.20.81.0
Locomotion velocity, NPP test1.01.53.11.6-1.7-1.8-1.6-1.4-0.6-0.8-0.20.50.7
Intraocular pressure1.21.74.11.8-1.6-2.0-1.7-1.4-0.7-1.0-0.30.50.2
Delta distance traveled before/after self-admin0.20.20.5-0.1-0.1-0.1-0.2-0.5-0.5-0.5-0.6-0.7-0.7
Delta ambulatory time before/after self-admin0.20.20.5-0.60.40.40.3-0.1-0.3-0.2-0.4-0.7-0.7
Parametrial fat weight0.40.91.6-0.40.30.30.40.91.21.21.31.21.3
Pavlov. Cond. lever latency4.45.510.9-3.32.83.22.92.81.92.11.20.0-0.3
Pavlov. Cond. magazine entry latency0.30.41.00.7-0.9-0.6-1.0-0.7-0.6-0.5-0.5-0.20.0
Pavlov. Cond. change in total contacts1.71.83.92.0-1.6-1.9-1.7-1.6-1.0-1.0-0.50.20.5
Pavlov. Cond. index score2.32.94.72.1-2.1-2.1-2.2-2.0-1.6-1.6-1.1-0.4-0.1
Pavlov. Cond. latency score2.02.54.42.1-1.9-2.0-2.0-1.9-1.5-1.5-1.0-0.30.0
Pavlov. Cond. lever contacts4.25.09.53.1-2.7-3.0-2.8-2.7-2.0-2.0-1.3-0.20.2
Pavlov. Cond. magazine entry number0.60.71.5-0.81.20.71.20.90.90.80.80.50.3
Pavlov. Cond. intertrial magazine entries0.20.20.40.5-0.5-0.5-0.6-0.5-0.6-0.5-0.5-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.2.53.15.02.0-2.2-2.0-2.2-2.1-1.7-1.7-1.3-0.6-0.4
Pavlov. Cond. response bias2.63.25.72.3-2.3-2.2-2.4-2.1-1.6-1.6-1.1-0.30.0
Pavlov. Cond. lever latency3.24.35.9-1.72.21.62.22.32.42.42.31.81.7
Pavlov. Cond. magazine entry latency0.20.20.8-0.50.20.50.20.1-0.3-0.2-0.5-0.7-0.9
Pavlov. Cond. change in total contacts2.23.66.00.5-1.7-0.4-1.7-1.5-2.3-2.1-2.4-2.4-2.4
Pavlov. Cond. index score1.21.63.10.3-1.0-0.2-1.0-1.0-1.5-1.4-1.7-1.7-1.7
Pavlov. Cond. latency score1.52.03.60.4-1.2-0.3-1.1-1.1-1.7-1.6-1.8-1.8-1.9
Pavlov. Cond. lever contacts2.53.44.81.4-2.0-1.3-1.9-2.0-2.2-2.2-2.1-1.7-1.6
Pavlov. Cond. magazine entry number1.41.73.9-0.10.90.10.90.91.51.41.71.82.0
Pavlov. Cond. intertrial magazine entries0.10.10.40.6-0.4-0.5-0.4-0.3-0.1-0.20.00.30.4
Pavlov. Cond. lever-magazine prob. diff.1.31.83.60.2-1.1-0.2-1.0-1.0-1.6-1.5-1.8-1.8-1.9
Pavlov. Cond. response bias1.92.64.00.8-1.5-0.7-1.6-1.5-2.0-1.9-2.0-1.8-1.8
Time in closed arm before self-admin0.30.41.0-1.00.70.80.70.70.60.60.40.1-0.0
Time in closed arm after self-admin0.30.41.2-0.6-0.20.5-0.3-0.1-0.6-0.3-0.8-1.1-0.7
Time in open arm before self-admin0.50.61.81.3-0.6-1.1-0.7-0.3-0.0-0.00.30.91.0
Time in open arm after self-admin0.50.51.51.2-0.3-1.0-0.2-0.40.2-0.00.61.10.8
Bone: periosteal estimation1.32.84.52.1-2.1-2.1-2.1-1.9-1.7-1.6-1.2-0.5-0.3
Bone: periosteal perimeter0.30.61.41.2-0.8-1.1-0.9-0.7-0.4-0.4-0.00.40.7
Bone: post-yield work1.21.74.62.2-1.6-1.9-1.5-1.4-0.7-0.9-0.20.60.9
Progressive ratio test 1 active lever presses1.01.23.00.31.7-0.41.40.41.30.71.41.50.7
Progressive ratio test 1 breakpoint0.81.02.40.41.6-0.51.30.31.10.51.31.40.7
Progressive ratio test 1 inactive lever presses0.71.12.91.5-0.0-1.40.1-0.50.60.21.11.71.3
Progressive ratio test 2 active lever presses1.51.84.30.22.1-0.21.70.71.50.91.71.80.8
Progressive ratio test 2 breakpoint1.61.94.50.12.1-0.11.80.81.60.91.71.80.9
Progressive ratio test 2 inactive lever presses0.10.20.80.90.4-0.60.1-0.4-0.0-0.30.20.50.2
Incentive Sensitization - Responses0.30.51.20.51.1-0.70.8-0.10.50.20.80.90.5
Incentive Sensitization - Breakpoint0.40.51.40.31.2-0.50.9-0.00.60.30.81.00.5
Sum of active levers in priming session hrs 5-64.94.56.1-1.52.41.72.22.42.52.52.31.91.7
Progressive ratio0.10.20.4-0.30.20.00.20.20.60.60.50.50.6
Food seeking constrained by brief footshock4.04.915.13.5-2.2-3.9-2.1-2.7-0.9-1.2-0.01.31.3
Seeking ratio, punishment vs. effort1.42.15.02.2-1.4-2.1-1.4-1.8-1.2-1.4-0.70.0-0.1
Retroperitoneal fat weight0.21.03.6-1.90.61.60.71.10.40.6-0.0-0.7-0.7
Reaction time number correct0.10.20.60.2-0.0-0.10.10.10.60.40.60.80.7
Reaction time mean minus median1.53.78.2-0.1-1.50.3-1.2-1.1-2.2-2.1-2.6-2.7-2.9
Reaction time mean minus median AUC1.33.45.80.6-1.6-0.4-1.5-1.5-2.2-2.2-2.4-2.3-2.4
Reaction time num false alarms0.40.61.40.3-0.20.0-0.4-0.5-0.9-0.9-1.0-1.0-1.2
Reaction time num false alarms AUC0.40.61.01.0-0.6-0.7-0.7-0.9-0.8-1.0-0.7-0.5-0.7
Reaction time trials correct on left0.10.20.60.2-0.0-0.10.10.10.60.40.60.80.7
Reaction time trials on left0.10.20.60.10.10.00.10.20.60.50.70.80.6
Reaction time mean1.01.74.1-1.80.31.60.50.6-0.7-0.4-1.3-2.0-2.0
Reaction time mean AUC1.21.94.6-1.90.41.70.60.6-0.7-0.4-1.3-2.1-2.2
Median of all reaction times1.21.75.1-2.31.22.01.31.40.30.6-0.3-1.1-1.1
Reaction time omissions1.21.84.0-1.61.42.01.51.91.11.30.70.10.2
Reaction time false alarm rate0.30.41.10.2-0.00.1-0.2-0.4-0.8-0.8-0.8-0.9-1.0
Reaction time premature initiation rate1.21.64.5-2.11.12.11.21.50.40.7-0.0-0.8-1.0
Reaction time premature initiations0.71.33.6-1.81.01.91.21.40.70.90.3-0.3-0.5
Std. dev. reaction times1.42.56.9-0.9-0.80.9-0.5-0.3-1.6-1.4-2.1-2.6-2.6
Reaction time trials completed0.10.20.60.10.10.00.10.20.60.50.70.80.6
Reaction time trials AUC0.10.20.60.10.10.10.10.30.60.50.70.70.6
Run reversals in cocaine runway, females0.30.31.1-0.8-0.30.40.0-0.0-0.2-0.3-0.5-0.7-1.1
Run reversals in cocaine runway, males0.00.00.1-0.20.20.20.20.20.10.10.0-0.1-0.1
Latency to leave start box in cocaine runway0.60.71.41.0-1.0-0.8-1.2-0.8-0.9-0.8-0.8-0.4-0.2
Latency to leave start box in cocaine runway, F0.30.40.7-0.20.40.30.20.80.70.80.70.70.9
Latency to leave start box in cocaine runway, M2.32.14.22.1-1.6-1.8-1.6-1.7-1.5-1.5-1.1-0.4-0.3
Std. dev. time between licks in bursts0.20.20.6-0.70.70.70.60.50.20.30.1-0.2-0.3
Total sessions with >9 infusions0.60.82.01.01.0-1.10.8-0.20.70.11.01.40.6
Short access day 1 total inactive lever presses0.81.02.61.5-0.3-1.6-0.1-0.60.40.10.81.51.4
Short access day 10 total inactive lever presses0.51.11.91.3-1.4-1.0-1.4-1.3-1.1-0.9-0.9-0.50.1
Short access day 1 total infusions0.81.12.91.20.9-1.30.7-0.20.80.31.21.71.1
Short access day 10 total infusions1.01.33.10.11.2-0.41.00.61.50.91.61.81.0
Short access total infusions1.21.53.60.61.5-0.71.40.41.40.71.61.91.0
Short access day 1 locomotion1.92.33.6-1.31.81.11.71.61.91.61.81.50.7
Short access day 10 total locomotion0.40.72.0-1.40.91.20.80.70.40.30.1-0.4-0.9
Short access total locomotion0.81.01.8-0.81.10.61.11.01.30.91.21.10.3
One hour access (0.3 mA shock)0.40.41.20.80.7-0.60.60.10.50.10.81.10.5
Compulsive drug intake0.30.30.6-0.3-0.70.2-0.5-0.2-0.7-0.4-0.7-0.8-0.5
One hour access (shock baseline)0.91.33.50.81.1-0.70.90.41.20.81.61.91.4
Social response proportion1.21.43.6-1.91.01.90.91.70.71.00.2-0.5-0.1
Social responses0.40.61.40.9-1.2-0.8-1.1-0.7-0.6-0.6-0.5-0.20.1
Social time0.10.10.60.10.20.00.00.30.30.40.30.30.8
Soleus weight1.03.17.60.30.8-0.50.70.92.01.92.42.72.8
Bone: stiffness3.86.28.93.0-3.0-2.7-3.0-2.9-2.5-2.7-2.1-1.1-1.0
Tibialis anterior weight4.715.831.65.5-5.0-5.6-5.0-4.7-3.1-3.4-1.80.20.6
Time to tail flick, vehicle, before self-admin0.60.61.8-1.30.71.30.60.80.50.60.2-0.3-0.2
Time to tail flick, vehicle, after self-admin0.10.10.3-0.1-0.3-0.1-0.3-0.3-0.4-0.3-0.4-0.4-0.5
Time to tail flick, test, before self-admin0.40.40.90.8-0.4-0.9-0.7-0.9-0.6-0.7-0.4-0.2-0.2
Time to tail flick, test, after self-admin2.12.23.50.3-1.7-0.6-1.9-1.3-1.7-1.6-1.8-1.6-1.5
Delta time to tail flick, vehicle, before/after SA0.30.30.70.8-0.6-0.8-0.6-0.7-0.5-0.5-0.3-0.1-0.1
Delta time to tail flick, test, before/after SA0.30.30.8-0.8-0.40.7-0.20.1-0.4-0.3-0.7-0.9-0.8
Tibia length0.30.92.60.70.2-0.50.30.40.90.81.21.61.6
Ambulatory time before self-admin1.62.37.32.7-1.5-2.5-1.5-1.6-0.8-1.0-0.20.80.9
Ambulatory time after self-admin0.91.02.71.6-0.9-1.5-1.0-1.1-0.9-0.9-0.6-0.10.1
Bone: tissue strength0.20.20.30.5-0.5-0.3-0.5-0.4-0.4-0.4-0.4-0.3-0.1
Total heroin consumption2.02.43.6-0.61.80.91.81.51.81.61.91.81.1
Bone: trabecular number1.21.92.60.9-1.6-0.8-1.5-1.5-1.6-1.6-1.6-1.3-1.3
Bone: trabecular spacing0.10.20.30.1-0.2-0.0-0.3-0.2-0.5-0.5-0.6-0.6-0.5
Bone: trabecular thickness0.20.20.4-0.60.30.70.30.4-0.10.0-0.3-0.5-0.7
Bone: trabecular tissue density2.43.66.12.5-2.3-2.4-2.2-2.2-1.8-2.0-1.2-0.3-0.3
Water consumed over 24 hours0.81.11.81.3-1.1-1.3-1.2-1.3-1.1-1.0-0.8-0.4-0.3
Number of responses in last shaping day3.13.48.00.41.1-0.21.31.42.21.92.52.82.6