Hub : Genes

Ubxn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Ubxn1 0.11 0.06 1.6e-06 0.03 0.08 0.08 0.08 9.6e-04 1.1e-06 7.6e-07 5.9e-07
2 BLA gene expression Ubxn1 0.08 0.05 4.1e-04 0.03 0.05 0.04 0.03 1.1e-02 1.9e-03 2.9e-03 6.3e-03
3 PL gene expression Ubxn1 0.03 0.02 4.4e-04 0.04 0.03 0.03 0.03 6.6e-05 1.4e-04 1.9e-04 2.0e-04
4 Brain gene expression Ubxn1 0.05 0.04 2.9e-04 0.01 0.03 0.03 0.02 5.2e-02 3.8e-04 1.9e-03 7.6e-03
5 NAcc gene expression Ubxn1 0.05 0.03 2.8e-10 0.07 0.07 0.07 0.07 2.5e-11 1.8e-10 1.2e-10 8.8e-11
6 Adipose intron excision ratio chr1_215194453_215194539 0.17 0.08 7.5e-10 0.06 0.06 0.05 0.06 6.4e-07 1.2e-07 1.8e-06 1.5e-07
7 Adipose intron excision ratio chr1_215187888_215194539 0.09 0.05 2.1e-05 0.04 0.04 0.04 0.04 2.6e-05 3.1e-05 2.5e-05 1.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.20.50.1-0.40.7-0.40.6-0.50.3
Area under the delay curve0.10.10.50.50.10.10.20.20.4-0.7
BMI with tail0.93.17.90.1-1.82.8-1.62.8-0.60.0
BMI without tail0.10.71.40.1-0.71.1-0.31.20.8-1.2
Body weight1.67.114.8-1.7-3.23.8-2.83.80.4-0.0
Weight adjusted by age0.30.81.2-0.8-1.01.1-1.00.8-0.40.8
Bone surface1.32.64.3-0.9-1.72.1-1.81.9-1.11.4
Bone volume0.71.32.1-0.3-0.91.3-1.21.1-1.31.5
Breakpoint value in progressive ratio session1.62.95.0-2.2-2.01.7-2.11.80.11.0
Number of licking bursts0.00.00.0-0.20.00.20.1-0.00.10.1
Context. condit. distance diff. score0.60.81.51.20.8-0.81.0-0.40.3-1.1
Locomotion velocity, session 10.50.62.30.40.1-0.10.60.11.1-1.5
Locomotion distance, session 10.40.51.30.1-0.50.6-0.10.90.8-1.2
Locomotion velocity, session 21.61.93.8-1.2-1.61.7-1.62.00.20.1
Locomotion distance, session 20.20.30.7-0.3-0.40.3-0.30.60.8-0.9
Locomotion velocity, session 30.20.20.50.7-0.10.50.20.50.1-0.7
Locomotion distance, session 30.20.20.6-0.0-0.20.20.20.10.8-0.8
Stereotopy head waving bouts, day 30.50.62.31.50.8-0.60.6-0.2-0.6-0.3
Stereotopy head waving duration, day 30.30.31.21.10.6-0.50.4-0.1-0.1-0.5
Locomotion velocity, session 70.10.10.20.40.2-0.20.00.1-0.40.2
Locomotion distance, session 70.30.41.20.80.5-0.40.7-0.20.5-1.1
Stereotopy head waving bouts, day 70.30.40.9-0.0-0.30.4-0.60.6-1.00.9
Stereotopy head waving duration, day 71.11.42.2-1.0-1.31.4-1.41.5-0.40.8
Locomotion velocity, session 80.50.62.1-0.00.1-0.40.40.01.3-1.4
Locomotion distance, session 80.50.71.91.41.0-0.80.9-0.5-0.2-0.7
Degree of sensitization distance0.30.41.51.20.6-0.30.5-0.1-0.6-0.2
Degree of sensitization stereotypy1.11.21.8-0.8-1.01.1-1.31.2-1.01.3
Conditioned locomotion0.40.40.6-0.7-0.80.8-0.70.80.4-0.1
Cocaine response after cond. corrected0.91.32.81.20.9-1.11.3-0.71.0-1.7
Cocaine response after cond. not corrected0.50.81.41.00.8-0.81.1-0.60.6-1.2
Cocaine response before conditioning0.70.91.9-0.8-0.70.9-0.90.7-1.01.4
Saline control response2.23.04.4-1.9-2.02.0-1.62.11.4-0.7
Bone: connectivity density0.81.32.9-0.5-1.41.7-1.21.6-0.20.3
Bone: cortical apparent density0.30.51.3-1.1-0.90.5-0.90.70.40.2
Bone: cortical area0.71.21.7-0.9-1.01.3-1.21.2-0.71.1
Bone: cortical porosity0.10.10.4-0.6-0.2-0.2-0.50.10.00.5
Bone: cortical porosity0.20.20.5-0.7-0.40.1-0.50.30.40.1
Bone: cortical thickness3.15.29.5-3.1-2.72.4-2.32.41.7-0.3
Bone: cortical thickness0.70.82.0-1.0-0.90.7-0.40.71.4-1.0
Bone: cortical tissue density0.50.81.7-1.3-1.00.6-1.00.80.50.2
Condit. Reinf. active minus inactive responses0.80.91.5-0.9-1.11.2-1.01.20.10.3
Condit. Reinf. active-inactive response ratio0.50.50.8-0.9-0.90.8-0.60.70.6-0.1
Condit. Reinf. active responses0.81.01.4-0.5-0.91.2-1.11.2-0.81.0
Condit. Reinf. inactive responses0.50.72.60.70.30.1-0.1-0.0-1.61.3
Incentive salience index mean0.70.91.9-0.7-1.11.4-0.91.3-0.00.2
Condit. Reinf. lever presses0.40.61.5-0.3-0.81.2-0.71.1-0.40.3
Condit. Reinf. active minus inactive responses0.30.51.60.10.3-0.3-0.2-0.2-1.21.3
Condit. Reinf. active-inactive response ratio1.11.75.60.90.9-0.7-0.0-0.5-2.42.0
Condit. Reinf. active responses0.10.20.3-0.5-0.40.3-0.50.5-0.30.5
Condit. Reinf. inactive responses0.60.82.6-0.8-0.70.50.00.51.6-1.3
Condit. Reinf. lever presses0.71.01.6-0.8-1.01.3-1.11.2-0.60.9
Condit. Reinf. lever reinforcers received0.30.40.6-0.7-0.60.5-0.80.7-0.30.7
Conditioned reinforcement - actives0.31.44.70.50.5-0.4-0.3-0.3-2.02.2
Conditioned reinforcement - inactives0.51.44.81.10.5-0.1-0.1-0.1-2.21.9
Conditioned locomotion2.13.16.92.62.1-1.71.6-1.6-1.50.3
Patch foraging indifference point 0 sec0.20.51.0-0.5-0.90.9-0.71.00.3-0.2
Patch foraging indifference point AUC1.22.84.6-1.8-1.61.4-2.11.4-1.12.1
Delay disc. indifference point, 0s delay0.91.02.51.60.9-0.71.1-0.60.3-1.1
Delay disc. indifference point, 16s delay0.10.10.30.2-0.10.3-0.20.3-0.50.4
Delay disc. indifference point, 2s delay0.50.51.61.30.8-0.60.7-0.4-0.70.1
Delay disc. indifference point, 24s delay0.20.30.8-0.0-0.20.30.10.30.8-0.9
Delay disc. indifference point, 4s delay0.50.52.00.2-0.30.40.10.51.1-1.4
Delay disc. indifference point, 8s delay0.40.61.40.60.6-0.60.9-0.70.8-1.2
Indifference point function ln k2.37.111.22.82.5-2.43.3-2.31.6-3.2
Indifference point function log k2.37.111.22.82.5-2.43.3-2.31.6-3.2
Patch foraging total patch changes 0 sec0.30.71.0-0.8-1.01.0-0.61.00.9-0.7
Patch foraging total patch changes 12 sec5.16.910.6-3.0-3.12.9-3.33.00.21.1
Patch foraging total patch changes 18 sec0.41.01.7-1.2-1.10.9-1.31.0-0.30.9
Patch foraging total patch changes 24 sec1.65.59.0-2.4-2.93.0-2.62.90.60.5
Patch foraging total patch changes 6 sec0.71.22.0-1.0-1.31.4-1.11.40.5-0.2
Patch foraging time to switch 0 sec0.20.71.70.3-0.30.6-0.80.8-1.31.1
Patch foraging water rate 0 sec0.20.71.10.30.7-0.81.1-0.90.9-1.0
Patch foraging water rate 12 sec0.93.76.11.31.7-1.72.4-1.81.8-2.5
Patch foraging water rate 18 sec1.22.67.61.10.9-0.81.9-0.92.0-2.8
Patch foraging water rate 24 sec1.31.92.81.21.3-1.51.7-1.31.0-1.6
Patch foraging water rate 6 sec2.02.95.31.01.4-1.52.1-1.61.8-2.3
Seeking ratio, delayed vs. immediate footshock0.00.00.10.1-0.10.20.00.10.1-0.3
Distance traveled before self-admin1.12.43.2-1.2-1.61.8-1.81.7-0.91.5
Distance traveled after self-admin0.40.71.5-1.2-1.00.9-1.00.7-0.00.7
Extensor digitorum longus weight4.116.229.1-3.9-4.95.4-4.35.01.30.2
Bone: elastic displacement0.40.51.3-0.10.4-0.70.6-0.61.1-1.0
Bone: elastic work1.11.42.9-1.1-1.21.0-0.61.11.7-1.3
Bone: endosteal estimation1.53.78.52.92.1-1.41.7-1.5-2.20.7
Bone: endosteal perimeter2.25.510.13.12.5-1.71.7-1.9-3.21.7
Epididymis fat weight0.73.66.72.42.0-1.41.4-1.6-2.61.4
Delta time in closed arm before/after self-admin1.91.75.0-0.6-0.90.8-0.21.02.1-2.2
Delta time in open arm before/after self-admin2.22.64.2-1.3-1.41.5-1.91.6-1.32.1
Diff in mean of infusions in LGA sessions1.42.53.9-1.9-2.01.7-1.81.81.0-0.1
Delay discount exponential model param0.10.10.5-0.4-0.0-0.1-0.2-0.2-0.40.7
Extinction: sum of active levers before priming1.92.94.7-1.7-2.02.2-1.92.10.10.6
Active lever presses in extinction session 63.03.14.6-1.7-1.91.8-2.11.9-0.81.7
Bone: final force1.01.62.9-1.0-1.41.7-1.41.6-0.50.7
Bone: final moment1.01.63.1-1.0-1.41.8-1.41.6-0.40.6
Food consumed during 24 hour testing period0.10.10.3-0.10.2-0.10.2-0.4-0.50.5
Glucose2.54.07.22.72.4-2.02.3-2.2-0.8-0.5
Heart weight1.01.63.41.81.1-0.61.5-0.60.5-1.7
Delay discount hyperbolic model param0.10.10.3-0.6-0.1-0.0-0.3-0.1-0.20.6
Intermittent access intake day 1-15 change0.42.13.51.01.4-1.50.6-1.4-1.91.8
Intermittent access intake escalation0.52.54.21.01.5-1.70.7-1.6-2.02.0
Intermittent access intake escalation 20.91.44.20.50.8-0.80.0-0.9-1.92.0
Intermitt. access day 1 inactive lever presses0.11.01.50.71.1-1.20.5-1.2-1.11.0
Intermitt. access day 15 inactive lever presses0.31.64.30.4-0.40.9-1.00.9-2.12.1
Intermitt. access escalation Index0.30.91.30.80.9-1.01.1-1.10.6-1.0
Intermittent access day 1 total infusions0.82.59.33.11.6-0.61.2-0.4-1.90.4
Intermittent access day 15 total infusions2.46.010.83.32.7-2.11.8-2.0-3.01.8
Intermittent access terminal intake (last 3 days)2.44.210.42.91.8-1.10.9-0.9-3.22.1
Intermittent access total infusions2.83.38.72.91.8-1.11.2-0.8-2.51.2
Intermittent access day 1 locomotion0.61.04.42.10.9-0.20.70.0-1.30.1
Intermittent access day 15 total locomotion0.62.26.92.01.0-0.40.2-0.2-2.61.9
Intermittent access total locomotion3.23.811.23.01.4-0.40.5-0.2-3.32.1
Intermittent access standard deviation0.21.11.91.01.1-1.10.7-0.9-1.41.1
Left kidney weight0.21.33.41.81.1-0.60.7-0.6-1.70.7
Right kidney weight0.10.71.81.20.8-0.40.4-0.5-1.30.8
Cocaine induced anxiety0.10.31.1-0.5-0.30.1-0.70.3-0.61.1
Post-drug Anxiety0.30.40.6-0.6-0.70.6-0.80.6-0.30.7
Baseline Anxiety0.40.61.6-0.3-0.60.6-0.00.51.2-1.3
Tail length0.31.63.2-1.8-1.41.1-0.90.91.6-0.8
Length with tail1.04.56.8-2.6-2.62.6-2.12.31.3-0.2
Length without tail1.26.510.4-2.8-3.13.2-2.53.01.5-0.4
Times rat made contact with spout0.50.51.7-0.8-0.50.3-0.10.41.3-0.9
Lifetime Intake1.92.47.22.71.7-1.01.3-0.8-1.70.4
Liver weight, left0.71.22.40.91.3-1.31.3-1.5-0.0-0.3
Liver weight, right1.72.94.82.01.8-1.62.2-1.80.4-1.5
Locomotor activity1.32.14.90.60.9-1.01.6-1.21.9-2.2
Locomotor testing distance1.22.86.91.11.1-1.21.9-1.22.0-2.6
Locomotor testing rearing0.62.24.11.11.2-1.41.8-1.31.4-2.0
Locomotion in novel chamber1.82.44.02.01.8-1.61.4-1.4-1.50.7
Locomotion in novel chamber post-restriction0.72.13.51.41.7-1.91.1-1.5-1.30.9
Fecal boli incidents, locomotor time 10.40.93.00.30.5-0.4-0.1-0.4-1.71.7
Change in fecal boli incidents, locomotor task1.61.72.71.31.2-1.21.5-1.21.0-1.6
Time >=10cm from walls, locomotor time 12.42.96.51.91.7-1.20.9-1.4-2.61.8
Bouts of movement, locomotor time 10.91.23.6-1.9-1.10.6-1.30.70.20.9
Total resting periods, locomotor time 10.91.02.6-1.6-0.90.5-1.20.6-0.11.2
Rest time, locomotor task time 10.71.22.40.71.3-1.51.0-1.4-0.60.4
Distance moved, locomotor task time 10.10.10.40.1-0.40.6-0.20.50.1-0.2
Vertical activity count, locomotor time 10.10.50.91.00.8-0.70.8-0.9-0.0-0.4
Time >=10cm from walls, locomotor time 20.20.72.7-0.20.10.0-0.4-0.1-1.41.6
Bouts of movement, locomotor time 20.41.32.0-1.4-1.41.3-1.21.30.40.3
Total resting periods, locomotor time 20.20.61.0-1.0-0.90.8-0.90.90.10.4
Rest time, locomotor task time 21.62.74.31.72.0-2.11.8-2.1-0.6-0.2
Distance moved, locomotor task time 20.60.81.7-1.3-1.10.9-0.90.90.50.2
Vertical activity count, locomotor time 20.20.51.8-0.7-0.3-0.00.1-0.11.3-0.9
Light reinforcement 10.00.00.0-0.20.1-0.10.2-0.10.20.0
Light reinforcement 20.81.86.00.70.6-0.3-0.2-0.2-2.42.3
Bone: marrow area1.74.19.23.02.3-1.61.9-1.7-2.20.6
Bone: maximum diameter0.50.93.00.2-0.10.5-0.60.5-1.71.6
Bone: maximum force1.32.64.7-0.8-1.62.2-1.72.0-1.21.3
Bone: maximum moment1.42.64.9-0.9-1.62.2-1.72.0-1.11.2
Mean time between licks in bursts0.21.54.6-0.5-0.60.70.30.42.1-2.1
Mean num. licks in bursts0.10.10.4-0.1-0.0-0.30.1-0.10.6-0.7
Cd content in liver0.80.91.51.01.0-0.90.5-0.8-1.20.9
Co content in liver1.01.12.5-0.10.6-1.01.0-0.91.6-1.6
Cu content in liver0.10.10.2-0.2-0.1-0.1-0.0-0.10.5-0.4
Fe content in liver0.00.00.10.30.2-0.20.2-0.10.1-0.2
K content in liver0.20.20.3-0.3-0.40.6-0.20.60.2-0.2
Mg content in liver0.20.21.00.40.20.00.50.10.5-1.0
Mn content in liver2.52.84.2-1.7-1.92.1-2.01.9-0.31.1
Na content in liver0.20.30.5-0.5-0.50.6-0.50.7-0.20.3
Rb content in liver2.42.74.21.51.8-1.92.1-1.80.6-1.4
Se content in liver0.40.51.6-0.1-0.10.3-0.50.2-1.21.3
Sr content in liver3.73.24.7-1.9-2.12.0-2.22.10.20.8
Zn content in liver1.82.13.7-1.4-1.71.8-1.71.90.40.1
Bone: minimum diameter1.22.35.02.21.6-0.81.1-1.0-2.21.0
Time in familiar zone, hab. session 10.00.00.10.2-0.10.30.10.20.0-0.2
Time in novel zone, hab. session 11.01.11.70.71.1-1.31.3-1.30.6-0.9
Total zone transitions, hab. session 10.20.20.4-0.6-0.60.5-0.50.60.4-0.1
Total locomotion distance, hab. session 10.20.30.90.70.5-0.30.1-0.1-0.90.5
Locomotion velocity, hab. session 10.10.20.50.0-0.20.3-0.50.5-0.70.6
Time in familiar zone, hab. session 20.50.51.3-0.10.2-0.40.8-0.71.1-1.1
Time in novel zone, hab. session 20.20.30.6-0.0-0.40.6-0.60.8-0.40.3
Total zone transitions, hab. session 20.70.91.7-0.5-1.11.3-0.71.30.8-0.8
Total locomotion distance, hab. session 20.10.10.20.4-0.10.30.00.40.1-0.5
Locomotion velocity, hab. session 20.10.10.30.60.10.10.10.3-0.4-0.1
Novel to familiar place preference ratio1.41.83.0-1.2-1.41.6-1.71.4-0.61.1
Novelty place preference0.91.22.0-0.9-1.11.3-1.41.1-0.61.1
Time in novel zone, NPP test0.91.11.9-0.9-1.11.3-1.41.1-0.50.9
Total zone transitions, NPP test0.71.01.9-0.8-1.21.1-0.91.40.8-0.6
Total locomotion distance, NPP test0.10.10.50.3-0.10.0-0.00.40.4-0.7
Locomotion velocity, NPP test0.00.10.20.2-0.1-0.1-0.10.30.3-0.5
Intraocular pressure0.10.10.2-0.30.1-0.3-0.1-0.4-0.10.4
Delta distance traveled before/after self-admin0.80.92.20.10.4-0.60.9-0.81.5-1.5
Delta ambulatory time before/after self-admin0.61.12.20.20.6-0.91.1-1.11.4-1.5
Parametrial fat weight2.15.09.83.12.5-1.71.7-1.8-2.81.4
Pavlov. Cond. lever latency0.50.61.30.30.8-1.20.8-1.10.4-0.4
Pavlov. Cond. magazine entry latency1.01.32.0-0.3-0.91.3-1.11.2-1.31.4
Pavlov. Cond. change in total contacts1.11.23.2-0.0-0.40.7-0.90.8-1.61.8
Pavlov. Cond. index score0.70.91.2-0.6-0.81.1-1.01.0-0.81.1
Pavlov. Cond. latency score0.40.51.0-0.3-0.71.0-0.70.9-0.60.7
Pavlov. Cond. lever contacts0.20.30.6-0.0-0.50.8-0.40.7-0.40.3
Pavlov. Cond. magazine entry number1.01.32.00.91.1-1.21.3-1.20.9-1.4
Pavlov. Cond. intertrial magazine entries0.40.51.2-0.7-0.40.2-0.90.3-0.61.1
Pavlov. Cond. lever-magazine prob. diff.0.91.11.8-0.5-0.91.1-1.11.0-1.01.3
Pavlov. Cond. response bias1.01.21.7-0.7-1.01.2-1.21.2-1.01.3
Pavlov. Cond. lever latency0.40.50.90.50.7-1.00.7-0.90.5-0.6
Pavlov. Cond. magazine entry latency3.65.17.8-2.3-2.72.7-2.62.8-0.01.0
Pavlov. Cond. change in total contacts0.92.22.9-1.1-1.41.6-1.61.5-1.21.7
Pavlov. Cond. index score2.03.14.4-1.5-1.92.1-2.02.1-0.81.5
Pavlov. Cond. latency score1.82.94.1-1.3-1.82.0-2.02.0-1.01.5
Pavlov. Cond. lever contacts0.40.50.8-0.6-0.70.9-0.70.8-0.50.7
Pavlov. Cond. magazine entry number6.07.811.72.83.3-3.33.3-3.40.3-1.5
Pavlov. Cond. intertrial magazine entries0.61.42.71.01.4-1.61.1-1.5-0.60.3
Pavlov. Cond. lever-magazine prob. diff.2.33.55.0-1.7-2.12.2-2.22.2-0.81.5
Pavlov. Cond. response bias1.52.03.5-1.3-1.71.9-1.61.7-0.30.8
Time in closed arm before self-admin0.30.62.00.40.3-0.1-0.0-0.2-1.41.4
Time in closed arm after self-admin0.81.01.61.01.1-1.01.2-1.00.3-0.9
Time in open arm before self-admin2.73.39.70.80.9-1.11.7-1.22.5-3.1
Time in open arm after self-admin0.60.71.0-1.0-0.90.7-0.70.71.0-0.6
Bone: periosteal estimation0.51.14.31.20.60.00.2-0.1-2.11.4
Bone: periosteal perimeter0.50.93.40.70.40.1-0.0-0.0-1.81.5
Bone: post-yield work1.32.28.01.90.9-0.10.3-0.3-2.81.8
Progressive ratio test 1 active lever presses0.40.71.71.30.9-0.60.6-0.4-1.00.4
Progressive ratio test 1 breakpoint0.40.71.71.30.9-0.60.5-0.4-1.10.6
Progressive ratio test 1 inactive lever presses0.20.51.0-0.1-0.60.9-0.71.0-0.50.5
Progressive ratio test 2 active lever presses1.62.25.41.91.4-0.90.6-0.7-2.31.6
Progressive ratio test 2 breakpoint1.72.25.41.91.3-0.90.6-0.6-2.31.6
Progressive ratio test 2 inactive lever presses0.72.26.31.91.2-0.70.4-0.4-2.51.9
Incentive Sensitization - Responses0.41.02.60.3-0.40.8-0.80.9-1.61.5
Incentive Sensitization - Breakpoint0.51.03.00.5-0.20.7-0.70.8-1.71.6
Sum of active levers in priming session hrs 5-63.23.07.3-1.8-1.31.1-2.11.1-1.52.7
Progressive ratio0.20.51.40.90.40.10.2-0.0-1.20.8
Food seeking constrained by brief footshock0.10.10.30.50.3-0.20.4-0.10.4-0.6
Seeking ratio, punishment vs. effort0.40.93.0-0.1-0.1-0.30.4-0.11.7-1.7
Retroperitoneal fat weight3.214.523.74.94.6-4.24.2-4.2-1.7-0.6
Reaction time number correct0.20.71.6-1.0-0.90.9-0.30.61.3-0.7
Reaction time mean minus median0.32.26.0-1.2-1.00.8-1.80.9-1.62.5
Reaction time mean minus median AUC0.10.92.2-1.3-0.70.4-1.20.5-0.61.5
Reaction time num false alarms0.91.54.70.20.3-0.70.9-0.62.0-2.2
Reaction time num false alarms AUC0.71.65.7-0.5-0.3-0.10.4-0.12.4-2.2
Reaction time trials correct on left0.20.71.6-1.0-0.90.9-0.30.61.3-0.7
Reaction time trials on left0.20.81.7-1.1-0.90.9-0.30.61.3-0.7
Reaction time mean0.30.62.3-0.2-0.1-0.2-0.6-0.0-1.31.5
Reaction time mean AUC0.30.62.3-0.10.1-0.2-0.4-0.2-1.31.5
Median of all reaction times0.20.31.00.10.0-0.2-0.3-0.0-1.01.0
Reaction time omissions0.50.81.5-1.2-1.00.5-1.10.80.00.8
Reaction time false alarm rate0.60.82.40.40.3-0.70.7-0.51.3-1.6
Reaction time premature initiation rate2.53.96.0-1.7-2.22.5-1.32.41.9-1.5
Reaction time premature initiations1.95.98.1-2.5-2.72.9-1.62.72.6-1.7
Std. dev. reaction times0.20.83.1-0.7-0.2-0.2-0.9-0.0-1.11.8
Reaction time trials completed0.20.81.7-1.1-0.90.9-0.30.61.3-0.7
Reaction time trials AUC0.20.71.7-0.9-0.80.8-0.20.51.3-0.8
Run reversals in cocaine runway, females0.80.93.70.5-0.20.60.50.61.3-1.9
Run reversals in cocaine runway, males0.20.30.60.30.6-0.70.5-0.70.2-0.3
Latency to leave start box in cocaine runway0.60.82.21.51.0-0.60.9-0.7-0.70.2
Latency to leave start box in cocaine runway, F0.00.00.10.30.00.20.00.2-0.20.1
Latency to leave start box in cocaine runway, M2.22.13.41.81.7-1.51.6-1.6-0.7-0.0
Std. dev. time between licks in bursts0.51.03.30.20.3-0.20.9-0.41.6-1.8
Total sessions with >9 infusions0.91.12.71.61.3-1.01.1-0.9-0.7-0.1
Short access day 1 total inactive lever presses0.20.31.51.20.5-0.10.6-0.2-0.3-0.4
Short access day 10 total inactive lever presses0.10.40.90.40.7-0.80.7-0.90.2-0.5
Short access day 1 total infusions1.01.94.52.11.7-1.41.6-1.2-0.6-0.4
Short access day 10 total infusions0.91.45.32.31.2-0.51.0-0.3-1.40.2
Short access total infusions1.21.75.32.31.4-0.91.4-0.7-0.6-0.7
Short access day 1 locomotion0.40.61.61.30.9-0.60.6-0.5-0.90.3
Short access day 10 total locomotion0.20.72.11.30.40.10.10.2-1.40.8
Short access total locomotion0.50.82.51.60.8-0.30.5-0.2-1.40.6
One hour access (0.3 mA shock)2.02.45.62.41.6-1.21.0-1.0-2.01.0
Compulsive drug intake1.52.15.3-1.9-1.30.9-0.60.72.3-1.6
One hour access (shock baseline)2.25.710.43.22.5-2.11.6-1.7-3.11.9
Social response proportion0.10.10.1-0.3-0.20.2-0.00.30.4-0.4
Social responses0.30.31.0-0.9-0.50.2-0.20.21.0-0.5
Social time0.20.31.0-0.8-0.2-0.2-0.0-0.01.0-0.7
Soleus weight2.16.29.22.63.0-3.03.0-3.0-0.3-0.8
Bone: stiffness0.71.32.8-0.6-0.81.2-1.20.9-1.41.7
Tibialis anterior weight6.823.234.1-5.2-5.85.8-5.65.81.01.3
Time to tail flick, vehicle, before self-admin0.20.30.80.60.00.3-0.20.4-0.90.5
Time to tail flick, vehicle, after self-admin0.10.20.50.4-0.30.50.00.50.4-0.7
Time to tail flick, test, before self-admin0.30.31.10.90.00.50.40.20.3-1.0
Time to tail flick, test, after self-admin0.20.20.8-0.3-0.20.2-0.40.1-0.70.9
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.3-0.50.4-0.20.40.8-0.8
Delta time to tail flick, test, before/after SA0.70.92.6-1.5-0.50.1-1.00.2-0.61.6
Tibia length1.85.08.1-1.5-1.92.2-2.72.1-2.02.9
Ambulatory time before self-admin0.82.53.6-1.2-1.51.6-1.81.6-1.31.9
Ambulatory time after self-admin0.20.30.8-0.4-0.50.6-0.60.4-0.60.9
Bone: tissue strength0.40.40.70.20.6-0.50.9-0.90.5-0.7
Total heroin consumption5.76.711.8-3.4-3.12.7-3.02.80.90.8
Bone: trabecular number0.40.71.8-0.2-0.91.4-0.91.1-0.50.4
Bone: trabecular spacing0.50.71.4-0.10.5-0.90.9-0.81.2-1.2
Bone: trabecular thickness0.30.41.20.50.5-0.30.2-0.5-1.11.0
Bone: trabecular tissue density2.44.38.91.62.5-3.02.2-2.7-0.2-0.4
Water consumed over 24 hours0.40.81.4-1.2-1.01.0-0.60.81.1-0.5
Number of responses in last shaping day0.30.41.1-0.4-0.40.3-0.10.51.0-1.0