Hub : Genes

Ubxn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ubxn1 0.03 0.02 4.3e-04 0.03 0.03 0.03 0.02 2.2e-04 2.7e-04 1.3e-04 1.1e-03
2 pVTA gene expression Ubxn1 0.07 0.05 5.6e-03 0.05 0.03 0.02 0.03 4.0e-03 1.7e-02 5.0e-02 1.8e-02
3 BLA gene expression Ubxn1 0.11 0.07 4.2e-05 0.03 0.06 0.04 0.05 1.6e-02 3.3e-04 1.9e-03 1.2e-03
4 Brain gene expression Ubxn1 0.05 0.03 1.8e-04 0.01 0.03 0.01 0.02 1.2e-02 7.9e-04 1.4e-02 1.0e-02
5 NAcc gene expression Ubxn1 0.06 0.03 4.8e-08 0.07 0.07 0.06 0.07 1.3e-08 2.1e-08 2.1e-07 2.9e-08
6 Adipose intron excision ratio chr1_205758779_205765430 0.09 0.05 2.0e-05 0.04 0.04 0.03 0.04 1.5e-05 2.9e-05 1.2e-04 2.4e-05
7 Adipose intron excision ratio chr1_205765344_205765430 0.17 0.08 7.1e-10 0.03 0.06 0.05 0.05 5.1e-04 2.3e-07 2.1e-06 2.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.20.30.20.6-0.3-0.30.5-0.3-0.5
Area under the delay curve0.10.10.5-0.40.10.20.30.10.70.3
BMI with tail0.93.07.51.52.7-1.4-1.72.60.1-0.2
BMI without tail0.61.12.30.81.5-1.0-0.91.40.80.7
Body weight2.39.518.03.24.2-3.3-3.33.80.31.3
Weight adjusted by age1.41.62.31.41.4-1.2-1.41.5-1.0-0.4
Bone surface1.42.43.31.61.8-1.4-1.71.7-1.5-1.1
Bone volume0.71.32.31.01.1-0.7-1.01.0-1.5-1.4
Breakpoint value in progressive ratio session2.32.64.52.11.5-1.9-2.01.6-1.20.1
Number of licking bursts0.00.00.00.00.10.10.1-0.1-0.1-0.1
Context. condit. distance diff. score0.60.81.3-1.1-1.00.91.0-0.51.10.3
Locomotion velocity, session 10.50.62.2-0.5-0.30.10.40.21.51.1
Locomotion distance, session 10.40.51.30.10.6-0.4-0.30.91.20.9
Locomotion velocity, session 21.92.23.91.51.8-1.6-1.72.0-0.10.4
Locomotion distance, session 20.20.30.80.10.4-0.4-0.30.60.90.9
Locomotion velocity, session 30.10.20.5-0.10.50.10.10.50.70.1
Locomotion distance, session 30.20.20.60.10.3-0.10.10.10.80.7
Stereotopy head waving bouts, day 30.40.51.1-1.1-0.61.00.6-0.10.3-0.7
Stereotopy head waving duration, day 30.30.41.0-1.0-0.70.80.6-0.20.6-0.2
Locomotion velocity, session 70.10.10.3-0.3-0.20.40.2-0.0-0.1-0.5
Locomotion distance, session 70.40.51.2-0.8-0.50.60.7-0.31.10.5
Stereotopy head waving bouts, day 70.40.51.30.30.2-0.2-0.50.5-1.1-1.1
Stereotopy head waving duration, day 71.41.82.71.51.6-1.4-1.61.6-0.8-0.2
Locomotion velocity, session 80.50.62.1-0.5-0.50.10.30.01.41.3
Locomotion distance, session 80.40.61.2-1.1-0.80.90.8-0.40.6-0.2
Degree of sensitization distance0.30.30.8-0.9-0.40.80.6-0.20.2-0.6
Degree of sensitization stereotypy1.21.31.71.21.0-1.0-1.31.2-1.3-0.9
Conditioned locomotion0.40.40.70.70.7-0.8-0.80.80.10.4
Cocaine response after cond. corrected1.41.53.0-1.5-1.21.01.2-0.81.70.9
Cocaine response after cond. not corrected0.91.01.7-1.3-1.00.91.1-0.61.30.6
Cocaine response before conditioning0.70.81.61.00.9-0.7-0.80.7-1.3-0.8
Saline control response2.02.73.61.81.9-1.8-1.61.90.71.4
Bone: connectivity density0.81.32.51.11.6-1.2-1.31.5-0.2-0.1
Bone: cortical apparent density0.50.71.21.00.7-1.1-1.00.8-0.00.6
Bone: cortical area0.81.31.81.31.3-0.9-1.11.3-1.1-0.7
Bone: cortical porosity0.00.00.10.1-0.3-0.1-0.2-0.0-0.4-0.1
Bone: cortical porosity0.10.10.20.3-0.0-0.5-0.50.3-0.10.4
Bone: cortical thickness2.94.86.82.62.4-2.6-2.32.40.41.8
Bone: cortical thickness0.80.92.20.80.7-1.0-0.60.81.01.5
Bone: cortical tissue density0.60.81.51.10.8-1.2-1.10.9-0.00.7
Condit. Reinf. active minus inactive responses0.80.91.31.11.1-1.1-1.01.1-0.30.2
Condit. Reinf. active-inactive response ratio0.40.40.70.80.6-0.9-0.70.70.10.6
Condit. Reinf. active responses0.81.01.31.11.1-0.9-1.11.2-1.1-0.8
Condit. Reinf. inactive responses0.50.62.5-0.10.10.4-0.0-0.0-1.3-1.6
Incentive salience index mean0.81.01.71.11.3-1.0-1.01.3-0.20.0
Condit. Reinf. lever presses0.40.51.20.71.1-0.6-0.61.0-0.2-0.2
Condit. Reinf. active minus inactive responses0.50.61.6-0.0-0.50.50.2-0.5-1.3-1.3
Condit. Reinf. active-inactive response ratio1.71.86.1-0.4-0.81.00.3-0.6-2.1-2.5
Condit. Reinf. active responses0.10.10.20.40.2-0.1-0.10.1-0.5-0.3
Condit. Reinf. inactive responses0.70.82.90.40.5-0.50.00.31.41.7
Condit. Reinf. lever presses0.91.21.81.41.3-1.0-1.11.1-1.0-0.5
Condit. Reinf. lever reinforcers received0.20.30.60.80.5-0.5-0.50.4-0.7-0.3
Conditioned reinforcement - actives2.02.03.0-1.2-1.61.31.0-1.4-1.5-1.7
Conditioned reinforcement - inactives1.31.43.6-0.9-0.91.20.8-0.9-1.4-1.9
Conditioned locomotion2.12.53.8-1.7-1.91.91.6-1.4-0.4-1.5
Patch foraging indifference point 0 sec0.40.71.20.90.9-0.9-0.91.10.10.4
Patch foraging indifference point AUC3.03.44.72.11.8-1.8-2.21.7-2.1-1.0
Delay disc. indifference point, 0s delay0.80.91.9-1.3-0.51.01.0-0.51.40.4
Delay disc. indifference point, 16s delay0.10.10.30.00.40.0-0.10.3-0.4-0.6
Delay disc. indifference point, 2s delay0.30.41.0-1.0-0.40.80.7-0.40.1-0.5
Delay disc. indifference point, 24s delay0.30.31.10.20.2-0.20.00.21.11.0
Delay disc. indifference point, 4s delay0.60.62.2-0.30.4-0.20.00.51.51.2
Delay disc. indifference point, 8s delay0.70.71.6-0.8-0.60.70.8-0.61.30.8
Indifference point function ln k5.57.611.4-3.1-2.62.63.2-2.43.41.6
Indifference point function log k5.57.611.4-3.1-2.62.63.2-2.43.41.6
Patch foraging total patch changes 0 sec0.50.81.10.90.9-1.0-0.81.00.61.0
Patch foraging total patch changes 12 sec6.07.711.73.32.9-3.2-3.43.2-1.30.2
Patch foraging total patch changes 18 sec0.70.91.51.10.9-1.1-1.21.0-0.9-0.2
Patch foraging total patch changes 24 sec5.46.69.93.03.1-2.9-3.03.1-0.50.7
Patch foraging total patch changes 6 sec0.81.32.11.31.3-1.2-1.21.50.10.5
Patch foraging time to switch 0 sec0.40.71.40.40.7-0.4-0.70.9-1.1-1.2
Patch foraging water rate 0 sec0.40.60.9-0.6-0.90.60.9-0.90.90.8
Patch foraging water rate 12 sec2.43.76.3-1.7-1.71.52.2-1.82.51.8
Patch foraging water rate 18 sec2.12.97.9-1.5-1.11.11.7-1.02.81.9
Patch foraging water rate 24 sec1.52.02.7-1.5-1.51.31.6-1.31.61.0
Patch foraging water rate 6 sec1.82.64.9-1.5-1.31.31.8-1.42.21.6
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.10.20.00.1-0.00.40.2
Distance traveled before self-admin2.32.43.61.91.7-1.6-1.81.6-1.3-0.5
Distance traveled after self-admin0.50.50.91.00.8-0.7-0.70.4-0.9-0.3
Extensor digitorum longus weight4.517.930.64.75.5-4.8-4.75.1-0.21.5
Bone: elastic displacement0.70.81.3-0.8-0.80.40.7-0.81.11.1
Bone: elastic work0.91.22.80.70.9-1.1-0.71.01.31.7
Bone: endosteal estimation1.63.55.8-2.0-1.62.41.9-1.6-0.8-2.4
Bone: endosteal perimeter2.65.311.9-2.0-1.82.72.0-1.9-1.9-3.5
Epididymis fat weight0.51.12.2-1.2-0.51.51.3-1.10.2-0.9
Delta time in closed arm before/after self-admin2.02.05.50.51.0-0.9-0.51.02.32.2
Delta time in open arm before/after self-admin2.32.23.51.51.3-1.4-1.71.4-1.9-1.0
Diff in mean of infusions in LGA sessions1.82.03.41.61.3-1.9-1.81.4-0.40.8
Delay discount exponential model param0.10.10.50.4-0.1-0.2-0.2-0.1-0.7-0.3
Extinction: sum of active levers before priming3.33.24.62.22.1-2.1-2.12.0-0.90.2
Active lever presses in extinction session 63.13.04.62.21.7-2.0-2.11.7-1.6-0.4
Bone: final force1.32.23.71.71.9-1.5-1.61.9-0.7-0.2
Bone: final moment1.32.13.71.71.9-1.5-1.61.8-0.7-0.2
Food consumed during 24 hour testing period0.10.10.30.2-0.10.20.2-0.4-0.6-0.5
Glucose2.64.06.3-2.2-2.02.52.3-2.3-0.1-1.4
Heart weight1.31.83.1-1.7-1.21.51.6-1.21.40.4
Delay discount hyperbolic model param0.10.10.50.5-0.1-0.2-0.2-0.1-0.7-0.3
Intermittent access intake day 1-15 change1.11.13.0-0.4-1.00.70.4-1.1-1.7-1.4
Intermittent access intake escalation0.80.82.3-0.3-0.80.50.2-0.8-1.5-1.2
Intermittent access intake escalation 20.70.73.10.6-0.0-0.3-0.60.0-1.7-1.1
Intermitt. access day 1 inactive lever presses1.61.72.6-1.6-1.41.61.4-1.4-0.4-1.2
Intermitt. access day 15 inactive lever presses0.60.62.4-0.00.50.2-0.10.3-1.3-1.5
Intermitt. access escalation Index0.90.82.2-1.1-0.30.70.9-0.61.50.8
Intermittent access day 1 total infusions1.61.83.5-1.7-1.21.91.5-0.60.1-1.6
Intermittent access day 15 total infusions3.43.95.6-2.0-2.12.31.8-1.7-1.3-2.4
Intermittent access terminal intake (last 3 days)1.71.86.0-0.9-0.91.30.7-0.4-1.7-2.4
Intermittent access total infusions1.61.84.2-1.3-1.21.61.1-0.7-1.0-2.0
Intermittent access day 1 locomotion0.80.91.7-1.3-0.71.31.0-0.00.8-0.8
Intermittent access day 15 total locomotion0.70.72.5-0.5-0.70.90.4-0.0-0.9-1.6
Intermittent access total locomotion1.21.45.5-0.8-0.61.20.60.2-1.2-2.4
Intermittent access standard deviation0.91.02.0-0.6-1.40.90.7-1.0-1.1-1.1
Left kidney weight0.10.30.9-0.00.40.1-0.20.1-0.8-0.9
Right kidney weight0.30.92.40.40.8-0.2-0.60.5-1.6-1.5
Cocaine induced anxiety0.40.51.00.80.5-0.5-0.70.5-1.0-0.6
Post-drug Anxiety1.11.22.41.20.9-0.9-1.20.9-1.5-0.8
Baseline Anxiety0.91.01.51.11.1-1.2-1.11.10.30.8
Tail length1.02.94.31.71.8-2.1-1.71.60.71.9
Length with tail1.86.610.42.93.2-3.0-2.92.80.01.4
Length without tail1.43.15.42.12.3-1.9-1.92.0-0.50.4
Times rat made contact with spout0.40.51.70.40.3-0.6-0.20.40.91.3
Lifetime Intake1.31.52.5-1.5-1.21.61.2-0.8-0.3-1.4
Liver weight, left0.30.50.9-0.5-0.70.70.8-0.90.60.3
Liver weight, right0.10.20.6-0.30.10.30.5-0.20.80.3
Locomotor activity1.42.25.0-1.2-1.30.91.4-1.22.21.8
Locomotor testing distance2.03.48.6-1.6-1.41.11.7-1.22.92.2
Locomotor testing rearing1.32.13.7-1.4-1.31.21.6-1.21.91.3
Locomotion in novel chamber2.32.95.0-1.6-1.71.91.4-1.5-1.4-2.2
Locomotion in novel chamber post-restriction1.92.24.1-1.6-2.01.71.5-1.7-0.4-0.9
Fecal boli incidents, locomotor time 10.91.03.30.0-0.30.40.0-0.3-1.8-1.8
Change in fecal boli incidents, locomotor task1.91.84.0-1.6-1.11.01.3-0.92.01.2
Time >=10cm from walls, locomotor time 12.72.75.8-1.3-1.51.81.3-1.4-1.5-2.4
Bouts of movement, locomotor time 10.70.81.51.20.1-1.1-1.10.6-0.90.2
Total resting periods, locomotor time 10.70.71.31.10.2-1.0-1.10.6-1.1-0.1
Rest time, locomotor task time 10.80.91.9-1.0-1.21.01.0-1.4-0.0-0.2
Distance moved, locomotor task time 10.10.10.30.20.5-0.3-0.30.60.10.0
Vertical activity count, locomotor time 10.60.60.9-0.9-0.90.90.9-0.80.3-0.2
Time >=10cm from walls, locomotor time 20.50.52.10.3-0.30.1-0.1-0.2-1.4-1.2
Bouts of movement, locomotor time 21.21.32.01.31.3-1.4-1.31.3-0.20.6
Total resting periods, locomotor time 20.60.61.01.00.9-1.0-0.90.9-0.20.3
Rest time, locomotor task time 22.52.94.5-1.9-2.02.02.0-2.10.3-0.6
Distance moved, locomotor task time 20.60.71.21.00.7-1.1-1.00.9-0.30.4
Vertical activity count, locomotor time 20.40.41.90.1-0.3-0.3-0.0-0.11.01.4
Light reinforcement 10.00.00.1-0.0-0.10.10.3-0.30.10.3
Light reinforcement 21.21.65.8-0.1-0.10.60.0-0.3-2.3-2.4
Bone: marrow area1.83.96.3-2.1-1.72.52.0-1.7-0.8-2.4
Bone: maximum diameter0.50.92.80.60.5-0.0-0.50.6-1.6-1.7
Bone: maximum force1.73.05.11.82.3-1.4-1.72.1-1.3-1.1
Bone: maximum moment1.62.84.91.82.2-1.4-1.72.0-1.2-1.0
Mean time between licks in bursts1.21.75.50.40.8-0.8-0.20.72.22.3
Mean num. licks in bursts0.10.20.6-0.1-0.2-0.10.1-0.10.60.8
Cd content in liver0.91.01.9-1.0-1.41.21.0-1.0-0.5-0.9
Co content in liver2.02.33.5-1.2-1.70.91.5-1.51.91.7
Cu content in liver0.40.51.60.30.4-0.6-0.30.41.01.3
Fe content in liver0.10.10.30.0-0.20.1-0.10.1-0.5-0.6
K content in liver0.70.71.41.01.2-0.6-0.81.0-0.6-0.6
Mg content in liver0.20.20.40.40.6-0.1-0.20.5-0.2-0.5
Mn content in liver1.92.13.41.81.8-1.5-1.71.5-0.9-0.2
Na content in liver0.80.81.31.11.0-0.7-0.90.9-1.0-0.7
Rb content in liver1.62.03.1-1.7-1.41.61.8-1.51.10.2
Se content in liver1.01.23.70.80.6-0.3-0.80.5-1.9-1.7
Sr content in liver5.14.76.82.52.5-2.5-2.62.5-0.90.4
Zn content in liver3.43.85.62.32.2-2.1-2.32.4-1.1-0.2
Bone: minimum diameter1.12.05.1-1.3-0.81.71.3-1.0-1.1-2.2
Time in familiar zone, hab. session 10.00.00.10.00.2-0.10.00.20.20.1
Time in novel zone, hab. session 11.21.11.6-1.1-1.21.11.2-1.30.90.4
Total zone transitions, hab. session 10.20.30.40.60.5-0.6-0.60.70.10.3
Total locomotion distance, hab. session 10.20.30.9-0.4-0.40.50.2-0.1-0.5-0.9
Locomotion velocity, hab. session 10.10.20.40.20.2-0.1-0.40.5-0.6-0.7
Time in familiar zone, hab. session 20.60.61.5-0.5-0.40.20.7-0.81.11.2
Time in novel zone, hab. session 20.30.30.70.50.6-0.4-0.60.8-0.3-0.4
Total zone transitions, hab. session 20.91.21.90.91.4-1.1-0.91.40.81.0
Total locomotion distance, hab. session 20.10.10.2-0.10.3-0.0-0.00.40.50.1
Locomotion velocity, hab. session 20.00.00.1-0.20.10.20.10.30.1-0.3
Novel to familiar place preference ratio1.92.02.91.61.7-1.4-1.71.5-1.1-0.5
Novelty place preference1.31.31.81.21.4-1.0-1.31.1-1.1-0.6
Time in novel zone, NPP test1.21.21.91.21.4-1.0-1.31.2-0.9-0.5
Total zone transitions, NPP test0.91.22.11.01.1-1.2-1.11.50.61.0
Total locomotion distance, NPP test0.10.10.5-0.20.1-0.1-0.10.40.70.5
Locomotion velocity, NPP test0.10.10.2-0.1-0.1-0.0-0.10.30.50.3
Intraocular pressure0.00.10.2-0.0-0.2-0.0-0.0-0.4-0.4-0.2
Delta distance traveled before/after self-admin0.70.71.0-0.9-0.70.71.0-1.00.90.7
Delta ambulatory time before/after self-admin1.11.21.5-1.1-1.00.91.2-1.21.20.8
Parametrial fat weight1.63.14.8-2.0-1.82.21.8-1.7-0.6-1.9
Pavlov. Cond. lever latency0.70.91.6-0.9-1.20.81.0-1.30.60.5
Pavlov. Cond. magazine entry latency1.01.31.91.11.2-0.9-1.11.2-1.4-1.1
Pavlov. Cond. change in total contacts1.01.13.10.70.4-0.4-0.70.7-1.8-1.6
Pavlov. Cond. index score0.70.81.21.00.9-0.8-0.90.9-1.1-0.8
Pavlov. Cond. latency score0.40.50.70.80.8-0.6-0.70.8-0.7-0.5
Pavlov. Cond. lever contacts0.10.20.30.40.5-0.3-0.40.5-0.4-0.4
Pavlov. Cond. magazine entry number1.11.32.4-1.3-0.91.01.2-1.11.50.9
Pavlov. Cond. intertrial magazine entries0.30.41.20.50.2-0.4-0.70.3-1.1-0.6
Pavlov. Cond. lever-magazine prob. diff.0.91.11.71.11.0-0.9-1.11.0-1.3-0.9
Pavlov. Cond. response bias0.91.11.71.11.0-0.9-1.11.0-1.3-0.9
Pavlov. Cond. lever latency0.30.40.8-0.7-0.90.50.6-0.80.50.4
Pavlov. Cond. magazine entry latency3.94.56.72.52.4-2.5-2.42.6-0.80.3
Pavlov. Cond. change in total contacts1.72.43.31.81.6-1.4-1.61.5-1.8-1.1
Pavlov. Cond. index score2.53.24.32.12.1-1.8-1.92.0-1.4-0.6
Pavlov. Cond. latency score2.22.83.81.91.9-1.6-1.81.9-1.4-0.7
Pavlov. Cond. lever contacts0.40.50.80.90.8-0.7-0.70.8-0.7-0.2
Pavlov. Cond. magazine entry number6.37.710.9-3.3-3.23.13.2-3.31.4-0.1
Pavlov. Cond. intertrial magazine entries1.11.52.4-1.3-1.51.41.3-1.5-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.2.73.54.92.22.2-2.0-2.02.2-1.3-0.4
Pavlov. Cond. response bias1.52.03.01.71.7-1.5-1.51.6-0.9-0.1
Time in closed arm before self-admin0.40.51.80.00.10.1-0.1-0.0-1.3-1.2
Time in closed arm after self-admin0.80.81.2-1.1-0.70.91.0-0.91.00.5
Time in open arm before self-admin2.62.87.6-1.4-1.10.91.4-1.22.82.1
Time in open arm after self-admin0.20.20.50.50.0-0.5-0.40.00.30.7
Bone: periosteal estimation0.51.14.6-0.3-0.00.80.3-0.1-1.5-2.1
Bone: periosteal perimeter0.60.93.60.10.10.50.00.0-1.6-1.9
Bone: post-yield work1.72.39.1-0.6-0.41.30.6-0.4-2.0-3.0
Progressive ratio test 1 active lever presses1.71.83.4-1.5-1.81.61.3-1.3-0.3-1.1
Progressive ratio test 1 breakpoint1.92.03.7-1.6-1.91.61.4-1.4-0.4-1.1
Progressive ratio test 1 inactive lever presses0.10.10.5-0.30.10.10.10.30.70.3
Progressive ratio test 2 active lever presses1.92.03.5-1.4-1.61.61.2-1.0-1.1-1.9
Progressive ratio test 2 breakpoint2.52.83.9-1.7-2.01.91.5-1.5-1.1-1.9
Progressive ratio test 2 inactive lever presses1.11.33.7-1.0-0.81.30.8-0.4-1.2-1.9
Incentive Sensitization - Responses0.40.41.40.20.20.0-0.30.5-1.1-1.2
Incentive Sensitization - Breakpoint0.50.51.70.00.10.2-0.20.4-1.2-1.3
Sum of active levers in priming session hrs 5-63.13.07.01.91.2-1.5-1.91.1-2.6-1.3
Progressive ratio0.20.20.60.20.20.20.1-0.0-0.7-0.8
Food seeking constrained by brief footshock0.30.41.1-0.6-0.30.30.5-0.31.00.8
Seeking ratio, punishment vs. effort0.70.82.8-0.7-0.40.10.4-0.21.71.4
Retroperitoneal fat weight2.47.812.4-3.4-2.83.53.3-3.10.7-1.3
Reaction time number correct0.60.91.71.11.1-0.9-0.60.60.81.3
Reaction time mean minus median1.51.96.01.20.7-0.9-1.30.8-2.4-1.6
Reaction time mean minus median AUC0.60.82.20.90.4-0.8-1.00.4-1.5-0.6
Reaction time num false alarms1.11.44.3-0.8-0.70.30.7-0.52.11.9
Reaction time num false alarms AUC1.01.45.3-0.2-0.2-0.40.10.12.12.3
Reaction time trials correct on left0.60.91.71.11.1-0.9-0.60.60.81.3
Reaction time trials on left0.71.01.81.11.1-1.0-0.60.70.81.3
Reaction time mean0.40.62.40.2-0.3-0.1-0.40.0-1.6-1.2
Reaction time mean AUC0.40.62.40.1-0.30.0-0.2-0.1-1.5-1.3
Median of all reaction times0.20.31.10.1-0.1-0.2-0.40.2-1.1-0.9
Reaction time omissions0.20.20.50.50.0-0.7-0.70.3-0.30.4
Reaction time false alarm rate0.60.82.2-0.9-0.80.40.6-0.41.51.2
Reaction time premature initiation rate2.93.96.11.82.5-2.1-1.62.31.52.0
Reaction time premature initiations4.36.18.72.42.9-2.7-2.12.61.72.6
Std. dev. reaction times0.50.73.20.4-0.3-0.3-0.5-0.1-1.8-1.1
Reaction time trials completed0.71.01.81.11.1-1.0-0.60.70.81.3
Reaction time trials AUC0.50.81.71.01.0-0.8-0.50.60.91.3
Run reversals in cocaine runway, females1.11.04.10.00.7-0.3-0.00.72.01.4
Run reversals in cocaine runway, males0.40.40.7-0.7-0.80.60.6-0.80.30.1
Latency to leave start box in cocaine runway0.50.50.9-0.9-0.61.00.8-0.5-0.1-0.7
Latency to leave start box in cocaine runway, F0.00.00.1-0.00.10.1-0.00.2-0.3-0.3
Latency to leave start box in cocaine runway, M2.92.84.0-2.0-1.92.01.9-1.90.1-0.7
Std. dev. time between licks in bursts0.91.13.4-0.7-0.40.40.9-0.51.81.6
Total sessions with >9 infusions2.12.44.2-2.0-1.61.91.8-1.40.8-0.6
Short access day 1 total inactive lever presses1.21.32.2-1.5-1.11.51.4-1.00.7-0.5
Short access day 10 total inactive lever presses2.42.63.8-1.9-1.61.82.0-1.61.60.5
Short access day 1 total infusions1.31.32.8-1.7-1.01.51.4-0.90.8-0.3
Short access day 10 total infusions0.80.92.0-1.4-0.81.31.0-0.40.3-1.0
Short access total infusions0.91.12.3-1.5-0.91.31.2-0.50.8-0.4
Short access day 1 locomotion0.20.20.5-0.7-0.10.50.40.30.7-0.2
Short access day 10 total locomotion0.20.20.4-0.6-0.20.50.30.20.2-0.6
Short access total locomotion0.20.20.3-0.50.10.40.20.60.6-0.3
One hour access (0.3 mA shock)3.54.16.3-2.3-2.22.52.1-2.0-0.7-1.9
Compulsive drug intake2.72.77.51.01.5-1.4-0.70.92.22.7
One hour access (shock baseline)5.26.09.9-2.2-2.72.71.9-2.2-2.2-3.1
Social response proportion0.20.20.40.30.6-0.3-0.20.40.40.5
Social responses0.20.31.00.50.4-0.6-0.30.20.51.0
Social time0.20.21.00.10.1-0.2-0.00.00.71.0
Soleus weight2.16.18.9-2.9-2.92.93.0-2.80.8-0.5
Bone: stiffness0.91.52.51.31.3-0.8-1.11.1-1.6-1.3
Tibialis anterior weight7.726.538.45.96.2-5.9-6.06.1-1.21.4
Time to tail flick, vehicle, before self-admin0.40.40.70.20.8-0.2-0.50.8-0.6-0.9
Time to tail flick, vehicle, after self-admin0.30.41.00.20.6-0.3-0.20.71.00.8
Time to tail flick, test, before self-admin0.30.31.4-0.10.50.20.20.51.20.5
Time to tail flick, test, after self-admin0.00.00.1-0.2-0.10.20.2-0.2-0.0-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.80.1-0.1-0.10.10.00.90.9
Delta time to tail flick, test, before/after SA0.30.31.10.5-0.2-0.5-0.5-0.1-1.1-0.3
Tibia length2.05.68.62.62.2-1.9-2.62.3-2.9-2.0
Ambulatory time before self-admin2.52.63.71.71.6-1.6-1.81.6-1.9-0.9
Ambulatory time after self-admin0.50.61.60.70.7-0.4-0.60.4-1.3-0.9
Bone: tissue strength0.20.20.5-0.3-0.10.50.6-0.70.30.1
Total heroin consumption3.84.57.32.72.2-2.6-2.52.2-0.70.9
Bone: trabecular number0.40.51.00.61.0-0.6-0.80.9-0.5-0.6
Bone: trabecular spacing0.40.61.5-0.4-0.50.20.6-0.51.21.2
Bone: trabecular thickness0.50.71.8-0.5-0.60.60.4-0.6-1.1-1.3
Bone: trabecular tissue density2.94.17.3-2.4-2.72.22.2-2.40.4-0.3
Water consumed over 24 hours0.50.60.90.90.9-0.9-0.60.60.40.9
Number of responses in last shaping day0.30.31.4-0.3-0.20.10.2-0.01.20.9