Hub : Genes

Ccdc107

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS NM_001107957.2 0.02 0.02 4.2e-03 0.02 0.01 0.01 0.01 4.6e-03 4.1e-02 1.3e-02 2.4e-02
2 NAcc gene expression Ccdc107 0.05 0.03 4.9e-06 0.04 0.03 0.04 0.04 1.7e-06 2.0e-05 1.7e-06 2.9e-06
3 Brain alternative TSS NM_001107957.2 0.06 0.04 2.4e-06 0.05 0.02 0.05 0.05 1.9e-05 8.2e-03 2.9e-05 2.6e-05
4 pVTA gene expression Ccdc107 0.1 0.06 3.5e-09 0.1 0.1 0.11 0.11 1.8e-08 2.4e-08 3.3e-09 2.1e-09
5 Brain alternative TSS XM_006238137.5 0.07 0.04 3.3e-06 0.04 0.01 0.04 0.04 4.9e-05 2.1e-02 8.8e-05 6.7e-05
6 Liver alternative TSS XM_039109982.2 0.05 0.04 1.9e-05 0.03 0.02 0.03 0.03 2.0e-04 8.9e-04 5.4e-04 5.8e-04
7 NAcc alternative TSS NM_001107957.2 0.03 0.02 3.1e-04 0.03 0.02 0.03 0.03 8.6e-05 1.2e-03 9.5e-05 5.5e-05
8 NAcc alternative TSS XM_039109982.2 0.03 0.02 4.3e-05 0.03 0.02 0.02 0.03 1.6e-05 5.0e-04 1.6e-04 4.5e-05
9 Brain alternative TSS NM_001107957.2 0.08 0.05 2.5e-07 0.07 0.03 0.07 0.07 2.2e-07 6.0e-04 5.7e-07 4.0e-07
10 Brain alternative TSS XM_006238136.5 0.05 0.03 3.6e-04 0.04 0.01 0.03 0.04 9.9e-05 1.5e-02 4.3e-04 1.8e-04
11 Brain mRNA stability Ccdc107 0.09 0.05 5.7e-09 0.08 0.07 0.09 0.09 7.2e-08 1.8e-07 4.6e-09 1.0e-08
12 pVTA mRNA stability Ccdc107 0.07 0.05 4.6e-06 0.06 0.06 0.07 0.07 7.0e-06 6.3e-06 1.9e-06 1.1e-06
13 NAcc mRNA stability Ccdc107 0.03 0.03 1.3e-04 0.04 0.01 0.03 0.04 9.9e-07 1.5e-02 9.3e-06 1.8e-06
14 NAcc alternative TSS XM_006238137.5 0.03 0.02 2.4e-04 0.02 0.03 0.02 0.02 1.5e-04 7.4e-05 1.5e-04 4.8e-04
15 RMTg gene expression Ccdc107 0.11 0.07 3.4e-03 0.06 0.07 0.03 0.06 8.9e-03 6.2e-03 6.3e-02 1.2e-02
16 BLA mRNA stability Ccdc107 0.05 0.04 9.0e-03 0.01 0.01 0.01 0.01 7.7e-02 6.7e-02 1.2e-01 1.1e-01
17 PL mRNA stability Ccdc107 0.04 0.03 7.7e-07 0.05 0.05 0.04 0.04 1.4e-06 1.9e-06 1.1e-05 1.1e-05
18 NAcc alternative TSS XM_006238137.5 0.02 0.01 1.3e-03 0 0.01 -0 0 7.9e-02 6.5e-03 6.2e-01 5.7e-02
19 Brain gene expression Ccdc107 0.08 0.06 5.2e-06 0.06 0.07 0.06 0.06 2.5e-06 8.4e-07 2.2e-06 4.2e-06
20 Liver gene expression Ccdc107 0.24 0.11 0.0e+00 0.15 0.16 0.16 0.16 6.9e-16 2.4e-17 4.1e-17 2.6e-17
21 Liver alternative TSS NM_001107957.2 0.05 0.03 4.6e-04 0.03 0.03 0.02 0.02 6.4e-04 5.2e-04 1.8e-03 1.0e-03
22 Adipose gene expression Ccdc107 0.28 0.11 0.0e+00 0.19 0.19 0.19 0.19 1.3e-20 1.5e-20 2.1e-20 1.3e-20
23 NAcc intron excision ratio chr5_62545739_62547190 0.02 0.03 8.1e-03 0.01 0.01 0.02 0.01 5.0e-03 1.1e-02 8.9e-04 4.3e-03
24 NAcc intron excision ratio chr5_62545739_62547187 0.02 0.02 7.4e-03 0.01 0.01 0.02 0.01 5.4e-03 5.1e-03 4.8e-04 4.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.22.23.81.61.4-1.4-1.41.5-1.51.4-1.3-1.61.6-1.71.7-1.5-1.3-1.71.6-1.8-1.8-1.0-0.80.80.81.9-1.7
Area under the delay curve0.40.61.7-0.4-0.70.70.6-0.60.6-0.70.60.6-0.60.8-1.30.70.50.8-0.71.10.90.20.2-0.1-0.7-1.01.1
BMI with tail1.65.48.72.42.3-2.2-2.42.3-2.42.3-2.3-2.22.2-2.62.5-2.4-2.3-2.72.7-2.5-2.7-2.0-1.91.90.42.9-2.1
BMI without tail1.26.58.22.92.8-2.7-2.82.6-2.62.8-2.7-2.42.4-2.92.8-2.7-2.6-2.82.8-2.6-2.8-2.3-2.12.10.22.4-1.5
Body weight3.415.119.34.44.3-4.2-4.34.2-4.24.1-4.2-4.14.1-4.23.7-4.0-4.2-4.04.2-3.4-3.9-4.1-4.03.9-1.33.0-1.2
Weight adjusted by age0.10.40.90.70.5-0.3-0.70.6-0.60.5-0.8-0.60.6-0.40.4-0.6-0.7-0.40.6-0.3-0.3-0.8-0.90.9-0.60.10.4
Bone surface0.81.62.11.41.4-1.4-1.31.4-1.41.3-1.2-1.51.5-1.41.3-1.3-1.3-1.41.4-1.2-1.4-1.2-1.11.1-0.01.3-0.8
Bone volume0.61.22.01.21.1-1.1-1.11.1-1.11.1-0.9-1.21.2-1.31.3-1.0-1.0-1.31.2-1.2-1.3-0.8-0.70.70.41.4-1.2
Breakpoint value in progressive ratio session0.81.48.40.1-0.20.30.2-0.30.3-0.20.10.3-0.30.7-1.40.00.01.1-0.61.91.3-0.8-1.11.3-2.9-1.92.9
Number of licking bursts1.75.17.22.22.4-2.4-2.42.3-2.32.4-2.3-2.32.3-2.52.7-2.3-2.2-2.62.4-2.5-2.6-1.8-1.61.60.52.4-1.8
Context. condit. distance diff. score0.10.10.2-0.5-0.40.50.4-0.40.4-0.50.40.4-0.40.4-0.30.30.40.3-0.30.20.20.40.4-0.40.40.1-0.3
Locomotion velocity, session 12.02.311.81.11.1-1.1-1.11.2-1.21.1-1.2-1.21.2-0.7-0.2-1.2-1.5-0.40.90.3-0.1-2.2-2.52.6-3.4-0.72.4
Locomotion distance, session 10.70.93.51.00.8-0.8-0.80.8-0.80.9-0.9-0.80.8-0.50.1-0.8-1.0-0.40.60.1-0.2-1.3-1.41.4-1.9-0.41.3
Locomotion velocity, session 22.22.64.01.81.6-1.5-1.71.7-1.71.5-1.7-1.71.7-1.71.9-1.7-1.5-1.91.8-2.0-1.9-1.2-1.00.90.61.7-1.5
Locomotion distance, session 22.12.94.32.02.1-2.1-2.01.8-1.82.1-1.9-1.81.8-1.71.5-1.8-2.0-1.41.5-1.2-1.3-1.9-1.91.7-1.30.00.7
Locomotion velocity, session 30.30.42.60.40.4-0.4-0.40.4-0.40.4-0.4-0.40.4-0.2-0.3-0.4-0.60.00.20.40.1-0.9-1.01.0-1.6-0.61.2
Locomotion distance, session 32.63.05.01.81.8-1.8-1.81.7-1.71.8-1.8-1.71.7-1.91.3-1.7-2.0-1.72.0-1.1-1.6-2.1-2.22.2-1.31.5-0.3
Stereotopy head waving bouts, day 30.40.43.40.1-0.10.10.10.1-0.1-0.10.1-0.10.10.4-0.7-0.0-0.10.6-0.40.70.7-0.5-0.60.6-1.6-1.31.8
Stereotopy head waving duration, day 30.30.41.5-0.4-0.50.50.5-0.30.3-0.50.50.3-0.30.7-0.70.30.30.8-0.70.70.80.10.1-0.1-0.8-1.11.2
Locomotion velocity, session 70.10.10.1-0.2-0.30.30.3-0.30.3-0.30.30.3-0.30.3-0.40.30.30.3-0.30.40.30.30.2-0.20.0-0.30.2
Locomotion distance, session 70.30.40.70.70.7-0.7-0.60.6-0.60.7-0.5-0.60.6-0.60.3-0.6-0.7-0.50.6-0.3-0.5-0.7-0.80.8-0.70.30.1
Stereotopy head waving bouts, day 71.41.72.71.31.2-1.2-1.31.4-1.41.2-1.3-1.41.4-1.31.0-1.4-1.5-1.31.4-1.0-1.2-1.6-1.61.7-0.91.1-0.1
Stereotopy head waving duration, day 70.60.71.10.90.8-0.9-0.91.0-1.00.9-1.0-1.01.0-0.80.7-1.0-1.0-0.80.8-0.8-0.7-1.0-1.01.0-0.60.40.1
Locomotion velocity, session 80.30.32.60.20.4-0.3-0.30.2-0.20.4-0.2-0.20.20.1-0.1-0.3-0.30.3-0.30.40.4-0.4-0.50.4-1.3-1.41.6
Locomotion distance, session 80.30.41.40.60.7-0.7-0.70.6-0.60.7-0.6-0.60.6-0.40.2-0.7-0.7-0.20.4-0.0-0.2-0.9-0.90.9-1.2-0.51.0
Degree of sensitization distance1.31.42.2-1.1-1.11.21.1-1.11.1-1.11.21.1-1.11.3-1.01.01.31.3-1.50.91.31.31.3-1.40.4-1.50.7
Degree of sensitization stereotypy1.51.62.51.31.2-1.2-1.31.3-1.31.2-1.3-1.31.3-1.41.2-1.2-1.3-1.51.6-1.2-1.4-1.3-1.31.4-0.21.6-0.8
Conditioned locomotion0.20.21.10.20.0-0.0-0.0-0.00.00.0-0.00.1-0.10.0-0.6-0.1-0.20.10.20.60.2-0.6-0.80.9-1.1-0.10.8
Cocaine response after cond. corrected1.21.93.8-1.4-1.21.21.3-1.31.3-1.21.31.3-1.31.4-1.91.30.91.6-1.31.91.70.50.2-0.1-1.8-1.62.0
Cocaine response after cond. not corrected1.21.75.5-1.2-1.01.01.1-1.01.0-0.91.11.0-1.01.3-1.71.10.71.6-1.31.71.70.30.0-0.0-2.0-2.02.3
Cocaine response before conditioning0.60.71.30.81.0-1.0-0.91.0-1.01.1-0.9-1.01.0-0.91.1-0.9-0.9-0.80.7-1.0-0.8-0.6-0.50.40.20.2-0.2
Saline control response0.91.22.81.11.3-1.3-1.11.1-1.11.3-1.0-1.21.2-1.00.7-1.0-1.3-0.81.0-0.4-0.7-1.4-1.51.5-1.7-0.00.8
Bone: connectivity density0.71.12.61.30.8-0.8-1.01.0-1.00.8-0.9-1.11.1-1.11.2-1.1-0.7-1.31.1-1.4-1.3-0.5-0.40.41.01.6-1.6
Bone: cortical apparent density0.20.32.7-0.2-0.30.30.3-0.10.1-0.20.30.3-0.30.00.40.20.5-0.1-0.2-0.5-0.20.80.9-1.01.60.5-1.2
Bone: cortical area2.03.25.71.72.0-2.0-1.81.5-1.52.0-1.6-1.61.6-2.12.4-1.6-1.5-2.11.8-2.3-2.2-1.0-0.70.61.42.1-2.2
Bone: cortical porosity0.20.20.4-0.3-0.50.50.4-0.40.4-0.60.30.4-0.40.6-0.40.20.50.4-0.50.30.40.40.5-0.50.2-0.40.2
Bone: cortical porosity0.00.00.10.1-0.00.0-0.10.1-0.1-0.1-0.2-0.10.10.0-0.0-0.2-0.1-0.10.1-0.0-0.1-0.2-0.20.2-0.20.10.0
Bone: cortical thickness0.71.25.70.61.0-1.0-0.80.4-0.40.9-0.6-0.50.5-1.31.5-0.5-0.5-1.31.0-1.5-1.50.10.2-0.32.01.9-2.4
Bone: cortical thickness0.40.51.4-0.8-0.50.50.7-0.80.8-0.50.80.8-0.80.5-0.20.70.80.5-0.60.30.41.11.1-1.11.2-0.2-0.4
Bone: cortical tissue density0.20.32.3-0.3-0.30.30.3-0.20.2-0.30.40.3-0.30.10.30.20.50.0-0.3-0.4-0.10.80.9-1.01.50.3-1.0
Condit. Reinf. active minus inactive responses0.40.50.90.60.6-0.6-0.60.9-0.90.6-0.7-0.90.9-0.60.9-0.9-0.7-0.80.6-0.9-0.8-0.5-0.40.30.40.4-0.4
Condit. Reinf. active-inactive response ratio0.70.81.2-1.1-1.01.01.1-0.90.9-0.91.10.9-0.90.9-0.70.91.00.9-0.90.70.81.01.0-0.90.5-0.70.2
Condit. Reinf. active responses2.53.25.11.81.7-1.7-1.92.1-2.11.8-2.0-2.12.1-1.82.2-2.1-1.8-2.01.8-2.3-2.0-1.5-1.21.00.61.4-1.1
Condit. Reinf. inactive responses3.03.96.42.12.1-2.0-2.22.2-2.22.1-2.2-2.22.2-2.02.5-2.2-1.9-2.21.9-2.5-2.2-1.4-1.10.90.91.6-1.5
Incentive salience index mean4.15.37.22.42.3-2.3-2.52.7-2.72.4-2.5-2.72.7-2.32.4-2.7-2.4-2.52.4-2.5-2.4-2.2-2.01.9-0.21.7-0.9
Condit. Reinf. lever presses10.115.219.54.34.1-4.0-4.24.4-4.44.1-4.3-4.34.3-4.03.7-4.4-4.2-4.04.0-3.7-3.9-4.1-3.83.6-1.22.7-1.2
Condit. Reinf. active minus inactive responses0.50.81.40.81.1-1.1-0.90.7-0.71.0-0.8-0.80.8-1.21.1-0.7-0.8-1.01.0-1.0-1.1-0.6-0.50.50.41.2-1.2
Condit. Reinf. active-inactive response ratio0.10.21.40.20.4-0.4-0.30.1-0.10.3-0.1-0.10.1-0.60.5-0.1-0.1-0.50.4-0.5-0.60.00.1-0.10.61.0-1.2
Condit. Reinf. active responses2.13.04.31.82.1-2.1-1.91.7-1.72.0-1.8-1.81.8-2.11.9-1.7-1.7-1.91.8-1.8-1.9-1.5-1.31.20.21.6-1.3
Condit. Reinf. inactive responses2.13.24.12.02.0-2.0-2.01.9-1.92.0-2.0-1.91.9-2.02.0-1.9-1.7-1.91.8-2.0-2.0-1.4-1.21.00.71.5-1.2
Condit. Reinf. lever presses2.23.25.61.81.9-1.9-1.91.8-1.81.9-1.8-1.81.8-2.12.3-1.7-1.5-2.01.7-2.4-2.1-1.0-0.70.51.41.9-2.1
Condit. Reinf. lever reinforcers received2.53.55.02.02.2-2.2-2.11.9-1.92.1-2.0-2.02.0-2.22.0-1.9-1.8-2.01.9-2.0-2.0-1.6-1.41.30.21.6-1.3
Conditioned reinforcement - actives0.00.10.40.40.1-0.1-0.30.1-0.1-0.0-0.6-0.10.1-0.3-0.1-0.1-0.2-0.20.40.1-0.1-0.5-0.50.6-0.60.6-0.0
Conditioned reinforcement - inactives0.10.30.9-0.4-0.50.50.4-0.60.6-0.50.20.7-0.70.5-0.90.10.40.6-0.40.90.60.10.00.1-0.6-0.30.6
Conditioned locomotion0.20.31.40.50.2-0.3-0.50.3-0.30.2-0.7-0.30.3-0.5-0.4-0.0-0.4-0.30.70.2-0.3-0.8-1.01.2-1.10.90.0
Patch foraging indifference point 0 sec0.61.76.81.40.9-0.9-1.00.9-0.90.9-1.2-0.80.8-0.9-0.4-1.3-1.3-0.71.20.3-0.4-2.1-2.32.5-2.60.51.1
Patch foraging indifference point AUC5.011.914.93.63.8-3.7-3.83.9-3.93.7-3.8-3.83.8-3.73.6-3.6-3.7-3.63.6-3.4-3.6-3.4-3.23.1-0.82.6-1.3
Delay disc. indifference point, 0s delay0.91.02.3-0.9-1.01.00.9-0.80.8-1.00.90.8-0.81.2-1.20.70.81.2-1.11.41.30.50.4-0.4-0.8-1.51.5
Delay disc. indifference point, 16s delay0.81.13.6-0.7-0.80.80.9-0.80.8-0.80.90.8-0.81.1-1.70.80.61.2-0.91.61.30.2-0.10.2-1.4-1.51.9
Delay disc. indifference point, 2s delay0.00.10.3-0.10.0-0.0-0.10.1-0.10.0-0.1-0.10.1-0.10.1-0.2-0.0-0.30.2-0.3-0.30.10.2-0.20.50.5-0.6
Delay disc. indifference point, 24s delay0.10.20.3-0.3-0.40.40.4-0.40.4-0.40.50.4-0.40.5-0.30.10.40.4-0.50.40.40.40.4-0.50.1-0.60.3
Delay disc. indifference point, 4s delay0.10.10.9-0.3-0.30.30.3-0.20.2-0.30.30.2-0.20.3-0.60.90.20.3-0.30.50.30.10.1-0.1-0.2-0.40.4
Delay disc. indifference point, 8s delay0.00.00.20.50.1-0.1-0.20.1-0.10.1-0.2-0.10.1-0.1-0.1-0.2-0.1-0.10.1-0.1-0.1-0.2-0.10.0-0.1-0.10.1
Indifference point function ln k1.44.15.3-2.1-2.32.22.2-2.22.2-2.22.22.3-2.32.2-2.31.92.12.2-2.12.22.21.81.7-1.60.2-1.71.2
Indifference point function log k1.44.15.3-2.1-2.32.22.2-2.22.2-2.22.22.3-2.32.2-2.31.92.12.2-2.12.22.21.81.7-1.60.2-1.71.2
Patch foraging total patch changes 0 sec0.82.37.21.81.2-1.3-1.41.3-1.31.2-1.5-1.21.2-1.30.0-1.7-1.7-1.11.6-0.1-0.9-2.3-2.52.7-2.51.00.7
Patch foraging total patch changes 12 sec2.53.34.72.11.7-1.7-1.91.8-1.81.7-1.9-1.81.8-2.01.7-1.9-1.9-2.02.1-1.6-2.0-1.8-1.81.8-0.22.2-1.3
Patch foraging total patch changes 18 sec0.61.31.91.41.3-1.3-1.41.2-1.21.2-1.4-1.21.2-1.21.0-1.2-1.2-1.11.1-0.9-1.0-1.3-1.21.2-0.70.8-0.3
Patch foraging total patch changes 24 sec1.24.15.22.12.1-2.1-2.22.1-2.12.1-2.2-2.12.1-2.21.7-2.0-2.2-2.12.3-1.7-2.0-2.3-2.32.3-1.01.8-0.7
Patch foraging total patch changes 6 sec3.25.49.22.62.3-2.3-2.52.4-2.42.3-2.6-2.32.3-2.41.4-2.5-2.6-2.22.6-1.5-2.1-2.9-2.93.0-1.91.8-0.3
Patch foraging time to switch 0 sec1.45.26.6-2.4-2.42.52.4-2.52.5-2.42.42.5-2.52.4-1.92.42.52.3-2.51.82.22.62.5-2.61.2-1.60.3
Patch foraging water rate 0 sec1.03.77.11.91.9-2.0-1.91.9-1.91.9-1.9-1.81.8-2.11.2-1.8-2.1-1.92.4-1.1-1.8-2.4-2.52.7-1.31.9-0.4
Patch foraging water rate 12 sec0.00.10.50.10.3-0.2-0.10.0-0.00.3-0.00.0-0.0-0.1-0.20.2-0.3-0.00.20.30.0-0.4-0.50.6-0.7-0.20.5
Patch foraging water rate 18 sec0.20.52.20.50.5-0.5-0.50.3-0.30.6-0.4-0.40.4-0.80.7-0.4-0.5-0.91.0-0.6-1.0-0.3-0.30.40.71.5-1.2
Patch foraging water rate 24 sec0.20.32.1-0.3-0.30.30.3-0.40.4-0.30.20.4-0.4-0.00.20.20.4-0.20.1-0.3-0.30.70.7-0.61.40.8-1.2
Patch foraging water rate 6 sec0.40.71.10.51.0-1.1-0.80.8-0.81.0-0.7-0.90.9-1.01.0-0.6-0.9-0.80.9-0.6-0.8-0.7-0.80.8-0.20.5-0.2
Seeking ratio, delayed vs. immediate footshock2.84.17.62.81.8-1.9-2.22.0-2.02.0-2.3-2.02.0-2.12.0-1.5-2.0-2.42.4-2.0-2.3-2.0-1.81.80.22.3-1.7
Distance traveled before self-admin2.04.36.42.22.4-2.4-2.42.4-2.42.4-2.5-2.42.4-2.11.8-1.4-2.3-1.92.0-1.6-1.8-2.3-2.32.2-1.20.80.1
Distance traveled after self-admin0.50.91.90.81.1-1.1-1.11.0-1.01.1-1.1-1.01.0-1.01.2-0.7-0.8-1.00.8-1.4-1.1-0.4-0.20.10.80.7-0.9
Extensor digitorum longus weight5.019.926.55.14.8-4.8-5.04.8-4.84.8-5.0-4.64.6-4.94.4-4.9-4.7-4.84.8-4.2-4.7-4.4-4.14.0-0.63.7-1.9
Bone: elastic displacement5.26.68.8-3.0-2.82.82.8-2.92.9-2.82.82.9-2.92.5-2.42.82.92.4-2.42.32.32.82.7-2.51.4-1.1-0.0
Bone: elastic work3.14.18.5-2.1-2.02.02.1-2.22.2-2.02.22.2-2.21.5-1.02.12.31.3-1.60.91.12.72.8-2.72.90.3-1.8
Bone: endosteal estimation1.22.84.01.71.9-1.9-1.81.9-1.91.9-1.8-2.02.0-1.61.7-1.8-1.9-1.61.6-1.3-1.5-1.8-1.81.7-1.10.60.1
Bone: endosteal perimeter1.22.84.01.81.9-1.9-1.81.7-1.71.9-1.8-1.91.9-1.71.4-1.8-2.0-1.61.7-1.2-1.5-2.0-2.01.9-1.40.80.2
Epididymis fat weight0.21.12.01.01.1-1.0-1.11.2-1.21.1-1.1-1.21.2-1.01.4-1.2-1.0-1.21.0-1.4-1.2-0.8-0.60.50.50.7-0.7
Delta time in closed arm before/after self-admin0.40.41.80.40.4-0.4-0.50.3-0.30.4-0.5-0.40.4-0.61.10.1-0.2-0.70.5-1.0-0.80.10.3-0.41.20.9-1.3
Delta time in open arm before/after self-admin0.20.31.00.3-0.40.30.3-0.40.4-0.40.30.4-0.40.6-1.0-0.00.30.6-0.40.80.7-0.1-0.10.1-0.9-0.81.0
Diff in mean of infusions in LGA sessions0.20.31.0-0.6-0.40.40.4-0.50.5-0.40.40.5-0.50.40.20.10.60.4-0.6-0.10.30.80.9-1.00.9-0.3-0.3
Delay discount exponential model param0.30.41.50.30.6-0.6-0.50.5-0.50.6-0.6-0.50.5-0.71.2-0.6-0.4-0.70.6-1.0-0.8-0.1-0.10.10.70.9-1.0
Extinction: sum of active levers before priming2.43.76.3-1.3-2.12.11.9-2.02.0-1.91.82.0-2.02.3-2.51.31.82.2-2.12.42.31.41.3-1.3-0.6-2.31.9
Active lever presses in extinction session 60.20.20.4-0.2-0.50.50.4-0.60.6-0.50.40.6-0.60.5-0.60.50.50.5-0.40.60.50.30.2-0.2-0.2-0.30.4
Bone: final force1.32.13.91.61.9-1.9-1.71.4-1.41.8-1.4-1.61.6-1.72.0-1.5-1.5-1.51.3-1.6-1.6-1.0-0.90.60.30.7-0.8
Bone: final moment1.01.63.51.41.7-1.7-1.51.2-1.21.6-1.2-1.31.3-1.51.9-1.2-1.2-1.41.1-1.5-1.4-0.7-0.60.30.60.7-0.9
Food consumed during 24 hour testing period0.40.91.51.11.2-1.2-1.11.0-1.01.2-0.9-1.01.0-1.00.9-1.0-1.1-0.90.9-0.7-0.8-1.0-1.00.9-0.60.20.3
Glucose2.84.55.72.22.3-2.3-2.32.2-2.22.3-2.4-2.12.1-2.32.1-2.3-2.3-2.32.3-2.0-2.2-2.1-2.02.0-0.41.9-0.9
Heart weight0.61.01.91.41.2-1.2-1.21.1-1.11.2-1.1-1.11.1-1.01.0-1.0-1.1-1.10.9-1.1-1.0-1.0-0.80.6-0.00.5-0.3
Delay discount hyperbolic model param0.20.31.10.20.4-0.4-0.40.4-0.40.4-0.4-0.40.4-0.51.0-0.5-0.3-0.50.4-0.8-0.60.00.0-0.10.70.8-0.9
Intermittent access intake day 1-15 change0.10.81.80.80.7-0.7-0.90.9-0.90.7-1.0-0.80.8-0.91.2-0.6-0.7-1.11.0-1.1-1.1-0.5-0.40.40.61.3-1.2
Intermittent access intake escalation0.10.61.50.60.6-0.6-0.70.7-0.70.6-0.8-0.70.7-0.81.2-0.4-0.6-0.90.8-1.1-1.0-0.3-0.20.20.81.2-1.2
Intermittent access intake escalation 20.61.04.00.60.6-0.6-0.70.7-0.70.6-0.7-0.70.7-1.01.5-0.4-0.5-1.21.0-1.5-1.3-0.10.0-0.11.51.8-2.0
Intermitt. access day 1 inactive lever presses0.11.63.91.51.4-1.4-1.41.3-1.31.3-1.4-1.31.3-1.31.1-2.0-1.4-1.31.3-1.0-1.2-1.3-1.31.3-0.50.8-0.2
Intermitt. access day 15 inactive lever presses0.00.10.20.50.1-0.0-0.30.1-0.10.1-0.4-0.10.10.00.20.1-0.3-0.20.20.0-0.1-0.4-0.40.4-0.4-0.30.4
Intermitt. access escalation Index0.20.61.50.50.9-0.8-0.91.0-1.00.9-1.1-1.01.0-0.70.6-1.2-0.9-0.60.6-0.7-0.6-0.8-0.80.8-0.60.20.1
Intermittent access day 1 total infusions0.51.43.6-0.7-1.31.31.0-1.11.1-1.30.81.2-1.21.2-1.90.90.91.3-0.81.91.40.1-0.10.3-1.6-0.81.5
Intermittent access day 15 total infusions0.00.10.90.3-0.10.1-0.20.1-0.1-0.1-0.4-0.00.0-0.20.1-0.0-0.1-0.30.5-0.1-0.3-0.3-0.30.4-0.10.9-0.5
Intermittent access terminal intake (last 3 days)0.10.21.00.40.0-0.0-0.30.2-0.20.0-0.4-0.20.2-0.30.2-0.4-0.2-0.40.6-0.0-0.4-0.5-0.50.7-0.41.0-0.4
Intermittent access total infusions0.20.21.00.50.0-0.1-0.30.2-0.20.1-0.5-0.20.2-0.3-0.1-0.4-0.3-0.30.60.2-0.2-0.8-0.81.0-0.90.80.0
Intermittent access day 1 locomotion0.51.03.5-0.5-1.11.00.9-1.01.0-1.10.81.0-1.00.9-1.90.70.81.0-0.61.61.10.1-0.00.3-1.3-0.51.1
Intermittent access day 15 total locomotion0.20.82.4-0.5-1.00.90.8-1.11.1-1.00.71.1-1.10.8-1.31.10.80.9-0.61.61.00.30.10.2-0.9-0.20.7
Intermittent access total locomotion1.01.22.1-0.9-1.41.31.2-1.41.4-1.41.01.4-1.41.1-1.51.31.21.0-0.81.31.00.80.7-0.5-0.2-0.00.2
Intermittent access standard deviation0.10.40.80.90.4-0.5-0.60.5-0.50.5-0.7-0.40.4-0.60.3-0.3-0.6-0.70.8-0.4-0.6-0.8-0.70.8-0.30.9-0.4
Left kidney weight0.43.04.52.12.1-2.1-2.01.8-1.82.0-2.0-1.81.8-1.61.3-1.7-2.0-1.41.5-1.0-1.3-2.0-2.01.9-1.60.10.7
Right kidney weight0.31.93.01.71.7-1.7-1.71.5-1.51.7-1.6-1.41.4-1.51.4-1.6-1.4-1.31.2-1.4-1.3-1.3-1.10.9-0.40.5-0.2
Cocaine induced anxiety0.10.20.6-0.8-0.40.40.5-0.40.4-0.40.60.4-0.40.5-0.40.50.40.5-0.50.30.50.50.5-0.50.1-0.60.3
Post-drug Anxiety0.50.61.00.81.0-0.9-0.81.0-1.00.9-0.7-1.01.0-0.60.6-0.9-0.8-0.50.4-0.6-0.4-0.7-0.70.6-0.6-0.50.6
Baseline Anxiety0.40.71.61.30.9-0.9-1.00.9-0.91.0-1.0-0.90.9-0.90.9-1.1-0.9-0.90.7-1.0-0.8-0.7-0.50.40.10.2-0.2
Tail length1.36.910.03.03.2-3.1-3.12.9-2.93.0-2.9-2.92.9-2.83.0-2.7-2.8-2.62.5-2.6-2.6-2.4-2.32.0-0.41.2-0.5
Length with tail1.77.610.63.33.2-3.1-3.13.0-3.03.0-3.0-3.03.0-2.72.3-2.9-3.1-2.52.7-1.9-2.3-3.2-3.13.0-2.01.00.4
Length without tail0.10.73.60.80.5-0.5-0.60.6-0.60.5-0.6-0.80.8-0.3-0.2-0.4-0.8-0.20.50.3-0.0-1.2-1.41.4-1.9-0.31.2
Times rat made contact with spout0.30.41.20.60.5-0.5-0.50.5-0.50.5-0.5-0.50.5-0.70.8-0.5-0.4-0.80.7-0.7-0.8-0.2-0.20.20.71.1-1.1
Lifetime Intake0.30.32.30.50.1-0.1-0.30.2-0.20.1-0.6-0.20.2-0.3-0.3-0.2-0.4-0.10.60.5-0.0-0.9-1.11.3-1.50.50.6
Liver weight, left0.00.10.60.00.0-0.10.0-0.10.10.00.1-0.10.10.2-0.2-0.20.00.3-0.30.20.30.00.0-0.1-0.4-0.80.7
Liver weight, right0.81.52.2-1.2-1.31.31.2-1.41.4-1.41.21.5-1.51.3-1.21.51.31.2-1.21.21.11.21.2-1.10.5-0.80.3
Locomotor activity0.00.00.30.10.0-0.0-0.10.1-0.10.1-0.1-0.10.10.1-0.0-0.5-0.00.0-0.1-0.10.0-0.00.0-0.0-0.1-0.30.2
Locomotor testing distance0.10.31.8-0.3-0.30.30.3-0.20.2-0.20.20.3-0.30.6-0.7-0.10.10.6-0.50.70.7-0.1-0.20.2-1.1-1.21.3
Locomotor testing rearing0.31.01.71.11.1-1.1-1.11.2-1.11.2-1.1-1.21.2-0.80.9-1.3-1.1-0.70.7-0.7-0.7-1.0-1.00.9-0.7-0.20.6
Locomotion in novel chamber0.40.50.9-0.7-0.70.60.7-0.80.8-0.80.70.7-0.70.4-0.60.80.80.4-0.50.20.30.91.0-0.90.90.5-0.8
Locomotion in novel chamber post-restriction0.51.44.40.81.1-1.1-1.01.0-1.01.0-1.0-1.11.1-1.32.1-0.4-0.7-1.41.0-1.8-1.5-0.20.1-0.21.61.5-1.9
Fecal boli incidents, locomotor time 10.41.01.8-0.7-1.31.41.0-1.11.1-1.31.01.1-1.11.2-1.00.71.10.8-1.00.80.81.01.1-1.10.7-0.60.1
Change in fecal boli incidents, locomotor task0.91.01.80.71.1-1.1-1.01.1-1.11.2-1.1-1.11.1-1.00.8-0.9-1.1-0.81.0-0.6-0.7-1.1-1.31.4-1.00.7-0.0
Time >=10cm from walls, locomotor time 10.20.31.30.30.5-0.5-0.30.3-0.30.4-0.3-0.30.3-0.3-0.3-0.4-0.5-0.10.30.30.0-0.7-0.90.9-1.2-0.20.8
Bouts of movement, locomotor time 11.62.12.9-1.6-1.71.71.6-1.51.5-1.71.51.5-1.51.7-1.51.31.51.5-1.61.31.51.41.4-1.40.3-1.20.6
Total resting periods, locomotor time 12.52.93.8-1.9-1.91.91.9-1.81.8-1.91.81.8-1.81.9-1.51.71.81.7-1.81.31.61.81.8-1.80.8-1.10.3
Rest time, locomotor task time 11.72.86.7-2.0-1.71.71.7-1.61.6-1.81.71.6-1.61.5-0.31.51.81.1-1.60.00.92.32.5-2.62.4-0.2-1.2
Distance moved, locomotor task time 11.13.16.22.01.9-1.9-1.81.9-1.91.9-1.8-2.02.0-1.60.9-1.6-2.0-1.31.7-0.5-1.2-2.2-2.42.5-2.10.50.8
Vertical activity count, locomotor time 10.32.26.61.51.3-1.4-1.31.6-1.61.5-1.4-1.61.6-0.90.4-1.2-1.7-0.71.10.3-0.5-2.0-2.22.2-2.6-0.51.8
Time >=10cm from walls, locomotor time 20.00.10.30.60.3-0.3-0.40.4-0.30.4-0.5-0.30.3-0.20.3-0.0-0.4-0.20.2-0.1-0.1-0.5-0.40.4-0.4-0.30.4
Bouts of movement, locomotor time 20.20.61.21.10.7-0.7-0.90.8-0.90.8-1.0-0.80.8-0.70.2-0.9-0.8-0.80.8-0.8-0.8-0.9-0.80.7-0.20.6-0.3
Total resting periods, locomotor time 20.00.20.50.70.3-0.3-0.50.4-0.40.4-0.6-0.40.4-0.4-0.0-0.7-0.4-0.50.5-0.4-0.4-0.5-0.40.4-0.00.5-0.3
Rest time, locomotor task time 20.71.12.5-1.6-1.11.11.3-1.11.1-1.21.31.1-1.11.0-0.71.11.21.0-1.00.80.91.31.2-1.10.7-0.3-0.1
Distance moved, locomotor task time 20.30.41.10.70.5-0.6-0.60.7-0.70.6-0.6-0.70.7-0.51.0-0.2-0.5-0.70.5-0.9-0.7-0.3-0.1-0.10.60.1-0.5
Vertical activity count, locomotor time 20.30.61.21.10.8-0.8-0.91.1-1.00.9-0.8-1.11.1-0.51.0-0.3-0.9-0.60.5-0.4-0.5-0.8-0.80.6-0.6-0.50.6
Light reinforcement 10.62.911.31.81.7-1.7-1.61.3-1.41.7-1.5-1.31.3-1.00.1-1.7-1.9-0.61.00.2-0.3-2.3-2.52.4-3.4-1.32.7
Light reinforcement 20.92.112.21.21.0-1.0-1.01.0-1.01.0-1.1-1.11.1-0.3-0.2-1.3-1.30.00.40.70.3-1.8-2.12.1-3.5-1.63.0
Bone: marrow area1.22.94.21.81.9-1.9-1.91.9-1.91.9-1.8-2.02.0-1.71.8-1.8-1.9-1.71.7-1.5-1.6-1.8-1.71.6-0.80.8-0.1
Bone: maximum diameter2.14.26.52.22.2-2.2-2.22.1-2.12.2-2.2-2.22.2-2.32.5-2.1-2.0-2.32.1-2.4-2.4-1.6-1.41.20.61.9-1.7
Bone: maximum force2.44.87.72.42.7-2.7-2.52.2-2.22.6-2.2-2.32.3-2.52.8-2.3-2.2-2.42.1-2.5-2.4-1.7-1.41.20.51.5-1.4
Bone: maximum moment2.03.86.62.22.4-2.4-2.21.9-1.92.3-1.9-2.02.0-2.22.6-2.0-1.9-2.11.8-2.3-2.2-1.3-1.10.80.71.4-1.5
Mean time between licks in bursts0.10.82.8-0.8-0.70.70.7-0.70.7-0.70.70.7-0.71.0-0.50.70.91.1-1.40.71.11.11.1-1.30.3-1.70.9
Mean num. licks in bursts0.92.53.2-1.6-1.81.81.7-1.61.6-1.81.71.6-1.61.8-1.71.61.71.7-1.71.71.71.51.4-1.40.2-1.40.9
Cd content in liver0.80.91.60.81.3-1.3-1.01.0-1.01.2-0.8-1.11.1-1.01.2-1.0-1.1-0.80.8-0.8-0.8-0.9-0.90.8-0.50.20.1
Co content in liver0.60.72.1-0.7-0.50.50.7-0.80.8-0.50.70.6-0.60.8-0.90.70.41.0-0.81.31.00.30.1-0.1-1.0-1.41.5
Cu content in liver2.12.43.3-1.8-1.61.61.7-1.61.6-1.61.81.5-1.51.7-1.31.71.61.7-1.81.31.61.71.6-1.70.5-1.70.9
Fe content in liver1.11.34.5-0.9-0.70.70.9-1.11.1-0.71.01.0-1.01.1-1.31.10.71.4-1.31.71.50.60.4-0.4-1.1-2.12.0
K content in liver0.20.20.8-0.4-0.30.30.4-0.30.3-0.30.40.3-0.30.5-0.70.40.20.6-0.40.70.60.0-0.10.1-0.9-0.70.9
Mg content in liver0.50.51.0-0.7-1.01.00.8-0.70.7-1.00.70.8-0.80.8-0.90.80.70.8-0.70.90.80.50.4-0.4-0.3-0.30.3
Mn content in liver0.91.12.20.91.0-1.0-1.01.0-1.01.0-1.0-0.90.9-1.11.4-0.8-0.8-1.21.0-1.5-1.3-0.5-0.30.20.81.3-1.4
Na content in liver2.12.34.6-1.7-1.31.31.5-1.61.6-1.31.61.4-1.41.7-1.11.61.51.7-1.91.41.71.61.6-1.70.3-2.21.3
Rb content in liver5.96.89.9-3.0-2.52.52.8-3.03.0-2.52.92.9-2.92.7-2.63.12.52.8-2.83.02.82.42.1-2.0-0.2-2.41.7
Se content in liver2.22.65.21.91.5-1.5-1.71.9-1.91.5-1.8-1.81.8-1.61.9-2.0-1.4-1.71.5-2.3-1.7-1.2-0.90.70.61.3-1.2
Sr content in liver0.90.81.71.30.7-0.7-1.01.3-1.30.6-1.3-1.31.3-0.60.6-1.3-0.8-0.70.6-1.0-0.6-0.9-0.70.6-0.30.3-0.1
Zn content in liver0.00.00.20.10.2-0.2-0.10.1-0.10.2-0.0-0.30.3-0.10.4-0.1-0.1-0.10.0-0.3-0.20.10.2-0.30.3-0.0-0.2
Bone: minimum diameter0.00.10.4-0.2-0.10.10.2-0.20.2-0.20.20.1-0.10.10.20.20.2-0.0-0.1-0.3-0.10.40.4-0.40.70.3-0.6
Time in familiar zone, hab. session 11.21.36.4-0.9-1.01.00.9-0.90.9-0.90.90.9-0.90.40.00.81.20.1-0.4-0.3-0.11.51.6-1.52.51.3-2.3
Time in novel zone, hab. session 11.92.211.0-0.8-0.70.80.8-0.90.9-0.80.80.9-0.91.5-1.70.90.61.7-1.51.91.90.2-0.0-0.1-2.3-3.13.3
Total zone transitions, hab. session 10.00.00.10.20.1-0.1-0.10.1-0.10.1-0.2-0.10.10.00.1-0.1-0.0-0.0-0.1-0.2-0.0-0.00.1-0.10.1-0.30.1
Total locomotion distance, hab. session 10.40.52.10.50.5-0.5-0.50.6-0.60.5-0.6-0.60.6-0.61.1-0.6-0.2-0.70.4-1.3-0.80.10.4-0.51.40.8-1.3
Locomotion velocity, hab. session 11.42.04.21.41.4-1.4-1.41.5-1.51.3-1.5-1.51.5-1.51.9-1.5-1.1-1.61.3-2.1-1.6-0.8-0.50.31.11.4-1.5
Time in familiar zone, hab. session 21.11.23.1-1.0-1.21.11.1-1.01.0-1.11.11.0-1.00.9-0.41.11.30.7-0.90.20.61.51.6-1.61.8-0.0-1.0
Time in novel zone, hab. session 21.11.24.5-0.9-0.70.80.8-0.90.9-0.80.80.9-0.91.1-1.50.90.61.3-1.01.71.40.1-0.20.2-1.8-1.72.1
Total zone transitions, hab. session 20.70.91.41.11.0-1.0-1.01.0-1.01.0-1.0-1.01.0-0.80.6-1.0-1.1-0.70.8-0.5-0.6-1.2-1.21.1-1.10.00.5
Total locomotion distance, hab. session 20.81.01.41.11.1-1.1-1.11.2-1.21.1-1.1-1.21.2-1.01.2-1.2-1.0-1.11.0-1.2-1.1-0.9-0.80.7-0.00.7-0.5
Locomotion velocity, hab. session 21.11.41.91.31.2-1.2-1.31.4-1.41.2-1.2-1.41.4-1.21.4-1.4-1.2-1.31.2-1.4-1.3-1.0-0.90.80.11.0-0.7
Novel to familiar place preference ratio2.53.36.0-1.7-1.71.81.7-1.81.8-1.81.71.8-1.82.0-2.31.91.52.1-1.92.52.21.00.8-0.7-1.3-2.22.2
Novelty place preference3.54.57.5-2.1-2.12.12.1-2.22.2-2.22.12.2-2.22.3-2.62.21.92.4-2.22.72.51.41.1-1.0-1.1-2.32.2
Time in novel zone, NPP test4.65.69.1-2.4-2.32.42.4-2.52.5-2.42.32.5-2.52.6-2.92.52.12.7-2.53.02.81.61.3-1.2-1.2-2.72.5
Total zone transitions, NPP test0.91.32.01.31.2-1.2-1.21.2-1.21.2-1.3-1.21.2-0.90.7-1.2-1.3-0.80.9-0.6-0.7-1.4-1.41.3-1.4-0.20.8
Total locomotion distance, NPP test2.23.14.31.91.8-1.8-1.92.0-2.01.8-1.9-2.02.0-1.71.4-2.0-2.0-1.61.8-1.4-1.6-2.1-2.02.0-1.30.90.1
Locomotion velocity, NPP test2.84.05.02.22.0-2.1-2.12.2-2.22.0-2.2-2.22.2-2.11.8-2.2-2.2-2.02.1-1.8-1.9-2.2-2.12.1-1.01.4-0.4
Intraocular pressure2.64.25.42.02.3-2.2-2.22.2-2.22.1-2.2-2.12.1-2.21.8-2.1-2.3-2.12.3-1.6-2.0-2.3-2.32.3-1.01.7-0.5
Delta distance traveled before/after self-admin0.30.30.9-0.7-0.40.40.5-0.50.5-0.50.60.5-0.50.5-0.2-0.20.60.4-0.60.00.30.80.9-0.90.8-0.2-0.3
Delta ambulatory time before/after self-admin0.61.12.3-1.3-1.01.01.1-1.11.1-1.11.11.1-1.11.1-0.60.31.21.0-1.20.50.91.41.4-1.50.9-0.80.0
Parametrial fat weight0.10.32.2-0.20.1-0.10.0-0.20.20.10.10.3-0.30.3-0.50.60.00.6-0.50.80.7-0.1-0.20.2-1.1-1.31.5
Pavlov. Cond. lever latency7.08.811.4-3.3-3.13.13.2-3.43.4-3.13.33.3-3.33.1-2.93.33.13.1-3.12.93.03.02.8-2.70.7-2.21.1
Pavlov. Cond. magazine entry latency0.50.61.01.00.9-0.9-0.91.0-1.00.9-0.9-0.90.9-0.80.9-1.0-0.8-0.80.7-1.0-0.8-0.6-0.50.40.10.3-0.4
Pavlov. Cond. change in total contacts2.83.14.01.91.8-1.8-1.92.0-2.01.8-1.9-2.02.0-1.81.7-1.9-1.9-1.81.8-1.7-1.8-1.8-1.71.7-0.51.2-0.5
Pavlov. Cond. index score3.24.05.42.32.1-2.1-2.22.3-2.32.1-2.3-2.22.2-2.12.2-2.3-2.0-2.12.0-2.2-2.1-1.8-1.61.4-0.01.4-1.0
Pavlov. Cond. latency score3.03.85.02.22.0-2.0-2.12.2-2.22.0-2.2-2.22.2-2.02.1-2.2-2.0-2.01.9-2.1-2.0-1.8-1.61.5-0.11.4-0.9
Pavlov. Cond. lever contacts6.57.89.93.12.9-2.9-3.03.1-3.12.9-3.1-3.13.1-2.92.8-3.1-2.9-2.92.9-2.8-2.9-2.7-2.52.4-0.42.2-1.3
Pavlov. Cond. magazine entry number0.70.81.3-1.0-1.01.01.0-1.01.0-1.01.01.0-1.01.0-1.11.00.91.0-0.91.11.00.60.5-0.4-0.4-0.70.7
Pavlov. Cond. intertrial magazine entries0.20.20.50.50.4-0.4-0.50.6-0.60.4-0.5-0.70.7-0.40.6-0.6-0.5-0.50.4-0.6-0.5-0.4-0.30.20.20.2-0.1
Pavlov. Cond. lever-magazine prob. diff.3.13.85.42.22.0-2.0-2.12.3-2.32.0-2.2-2.22.2-2.02.2-2.2-1.9-2.11.9-2.3-2.1-1.7-1.41.20.21.5-1.2
Pavlov. Cond. response bias3.94.96.42.52.4-2.4-2.42.5-2.52.4-2.4-2.52.5-2.32.3-2.5-2.3-2.32.2-2.3-2.3-2.1-1.91.7-0.21.5-0.9
Pavlov. Cond. lever latency2.23.15.1-1.8-1.91.91.9-1.81.8-1.81.81.9-1.91.9-2.21.71.52.0-1.72.32.01.10.7-0.6-1.2-1.71.8
Pavlov. Cond. magazine entry latency0.40.51.4-0.6-0.60.60.6-0.70.7-0.60.60.6-0.60.7-0.40.80.80.7-0.90.40.61.01.1-1.20.7-0.80.0
Pavlov. Cond. change in total contacts0.41.04.50.70.8-0.8-0.80.7-0.70.8-0.7-0.70.7-0.91.5-0.5-0.3-1.00.5-1.6-1.10.30.6-0.82.11.0-1.9
Pavlov. Cond. index score0.20.42.20.30.4-0.4-0.40.3-0.30.4-0.3-0.40.4-0.50.9-0.1-0.0-0.50.1-0.9-0.60.40.6-0.81.50.4-1.2
Pavlov. Cond. latency score0.30.52.60.40.5-0.5-0.50.4-0.40.5-0.4-0.40.4-0.61.0-0.2-0.1-0.60.3-1.1-0.80.30.6-0.71.60.7-1.5
Pavlov. Cond. lever contacts1.52.34.11.51.6-1.6-1.61.6-1.61.6-1.6-1.61.6-1.72.0-1.4-1.2-1.71.4-2.0-1.7-0.8-0.50.31.21.4-1.6
Pavlov. Cond. magazine entry number0.30.42.80.1-0.10.10.10.1-0.1-0.10.0-0.00.00.2-0.7-0.2-0.30.20.10.70.3-0.8-1.01.1-1.7-0.41.3
Pavlov. Cond. intertrial magazine entries0.20.51.00.60.7-0.7-0.70.6-0.60.7-0.7-0.60.6-0.80.6-0.7-0.8-0.80.9-0.5-0.8-0.8-0.90.9-0.41.0-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.42.50.20.4-0.4-0.30.3-0.30.4-0.3-0.30.3-0.51.0-0.10.0-0.50.1-0.9-0.60.50.7-0.91.60.5-1.3
Pavlov. Cond. response bias0.70.92.20.91.0-1.0-1.00.9-0.91.0-0.9-1.01.0-1.01.4-0.7-0.6-1.00.6-1.4-1.1-0.10.2-0.31.50.8-1.4
Time in closed arm before self-admin0.20.31.0-0.8-0.60.50.7-0.70.7-0.60.90.7-0.70.4-1.00.80.60.5-0.30.60.40.50.4-0.30.10.1-0.2
Time in closed arm after self-admin0.50.61.8-1.1-0.60.50.7-0.70.7-0.70.70.7-0.70.40.11.10.80.3-0.5-0.10.21.01.1-1.11.40.4-1.0
Time in open arm before self-admin1.21.42.21.31.3-1.2-1.31.4-1.41.3-1.4-1.41.4-1.01.2-1.5-1.3-0.91.0-0.7-0.8-1.4-1.41.3-1.10.10.5
Time in open arm after self-admin1.41.53.41.81.2-1.1-1.31.3-1.31.2-1.3-1.21.2-1.00.5-1.6-1.3-1.01.2-0.4-0.8-1.6-1.71.7-1.40.50.4
Bone: periosteal estimation1.53.55.41.92.2-2.2-2.11.9-1.92.2-1.9-2.12.1-2.12.3-1.9-2.0-2.01.9-2.0-2.1-1.6-1.41.30.11.4-1.1
Bone: periosteal perimeter0.51.11.61.11.3-1.3-1.20.9-0.91.2-1.1-1.11.1-1.11.0-1.1-1.2-1.01.1-0.8-1.0-1.1-1.11.1-0.60.6-0.1
Bone: post-yield work2.13.64.92.22.1-2.1-2.12.1-2.12.1-2.1-2.22.2-1.81.8-2.2-2.2-1.71.8-1.6-1.6-2.1-2.01.9-1.20.60.2
Progressive ratio test 1 active lever presses0.30.63.5-0.2-0.60.60.4-0.50.5-0.60.20.5-0.50.5-1.10.40.20.6-0.11.40.7-0.5-0.81.1-1.9-0.01.1
Progressive ratio test 1 breakpoint0.30.53.1-0.1-0.50.50.3-0.40.4-0.50.10.4-0.40.4-1.00.30.20.50.01.20.6-0.6-0.81.1-1.70.11.0
Progressive ratio test 1 inactive lever presses0.61.64.51.31.2-1.2-1.31.2-1.21.1-1.4-1.21.2-1.00.3-1.3-1.4-0.71.1-0.1-0.6-1.8-2.02.0-2.10.11.1
Progressive ratio test 2 active lever presses0.50.83.9-0.3-0.70.70.4-0.60.6-0.70.10.7-0.70.7-1.30.40.40.9-0.41.61.0-0.4-0.60.8-2.0-0.51.5
Progressive ratio test 2 breakpoint0.60.84.0-0.4-0.80.80.5-0.60.6-0.80.20.7-0.70.7-1.40.50.40.9-0.41.71.1-0.3-0.60.8-2.0-0.61.6
Progressive ratio test 2 inactive lever presses0.10.20.80.70.3-0.3-0.50.3-0.30.2-0.7-0.30.3-0.40.3-0.6-0.4-0.40.60.0-0.3-0.7-0.80.9-0.80.60.1
Incentive Sensitization - Responses0.10.41.3-0.4-0.50.50.3-0.50.5-0.50.00.6-0.60.6-0.90.40.40.7-0.51.20.80.0-0.10.2-1.0-0.71.1
Incentive Sensitization - Breakpoint0.20.41.4-0.4-0.50.60.4-0.60.6-0.60.10.6-0.60.6-0.90.50.40.7-0.51.20.80.0-0.10.2-1.0-0.71.1
Sum of active levers in priming session hrs 5-62.72.55.3-1.2-1.61.71.5-1.51.5-1.61.41.6-1.61.8-2.30.91.31.9-1.52.32.00.70.5-0.3-1.4-1.92.0
Progressive ratio0.00.00.20.30.1-0.1-0.1-0.10.10.2-0.1-0.00.0-0.0-0.2-0.3-0.10.00.00.20.1-0.2-0.20.1-0.4-0.30.4
Food seeking constrained by brief footshock8.410.514.83.83.5-3.6-3.63.5-3.53.5-3.6-3.53.5-3.42.1-3.4-3.6-3.13.5-2.2-2.9-3.8-3.83.8-2.12.2-0.3
Seeking ratio, punishment vs. effort1.22.73.61.61.8-1.8-1.81.9-1.91.8-1.8-1.91.9-1.81.4-1.6-1.8-1.71.8-1.5-1.6-1.7-1.71.8-0.61.4-0.6
Retroperitoneal fat weight0.42.03.0-1.4-1.41.41.4-1.61.6-1.41.51.5-1.51.4-1.01.61.51.3-1.51.01.21.71.7-1.71.1-1.10.2
Reaction time number correct0.10.30.70.60.6-0.6-0.50.4-0.40.6-0.4-0.40.4-0.60.0-0.5-0.5-0.30.50.1-0.3-0.7-0.80.8-0.80.30.3
Reaction time mean minus median0.10.96.80.30.1-0.1-0.30.1-0.10.2-0.3-0.10.1-0.41.2-0.50.2-0.70.2-1.3-0.90.81.1-1.32.61.1-2.2
Reaction time mean minus median AUC0.21.13.90.80.8-0.8-0.90.7-0.60.8-0.9-0.70.7-1.01.5-1.0-0.5-1.20.7-1.5-1.30.10.4-0.62.01.3-1.9
Reaction time num false alarms0.00.10.60.30.1-0.1-0.10.1-0.1-0.0-0.0-0.10.1-0.10.4-0.10.0-0.20.0-0.4-0.30.20.4-0.50.80.2-0.4
Reaction time num false alarms AUC0.20.41.11.00.7-0.7-0.80.7-0.70.7-0.7-0.70.7-0.70.8-0.7-0.7-0.80.7-0.6-0.8-0.6-0.50.40.10.6-0.3
Reaction time trials correct on left0.10.30.70.60.6-0.6-0.50.4-0.40.6-0.4-0.40.4-0.60.0-0.5-0.5-0.30.50.1-0.3-0.7-0.80.8-0.80.30.3
Reaction time trials on left0.10.20.60.50.5-0.5-0.40.3-0.30.5-0.3-0.30.3-0.4-0.0-0.4-0.4-0.20.40.2-0.2-0.6-0.70.7-0.80.20.4
Reaction time mean1.43.07.3-2.0-1.71.71.7-1.81.8-1.61.61.7-1.71.5-0.61.61.91.3-1.80.71.12.42.6-2.72.4-1.0-0.7
Reaction time mean AUC1.43.47.9-2.1-1.81.81.8-1.91.9-1.81.71.8-1.81.6-0.61.72.11.4-1.90.71.22.52.7-2.82.5-1.0-0.7
Median of all reaction times3.14.97.9-2.7-2.22.22.3-2.42.4-2.22.22.3-2.32.3-1.42.32.42.1-2.41.62.02.72.7-2.81.7-1.80.2
Reaction time omissions1.62.63.5-1.8-1.81.81.7-1.61.6-1.81.61.6-1.61.9-1.51.41.71.8-1.91.41.81.61.6-1.60.4-1.81.0
Reaction time false alarm rate0.10.10.50.1-0.30.30.1-0.10.1-0.30.10.1-0.10.20.20.20.20.0-0.2-0.2-0.00.40.5-0.60.70.1-0.3
Reaction time premature initiation rate2.33.65.5-2.1-2.32.32.2-2.22.2-2.32.12.2-2.21.9-1.72.12.11.6-1.61.51.52.12.0-1.81.2-0.2-0.6
Reaction time premature initiations0.72.23.2-1.6-1.81.81.7-1.81.8-1.71.71.8-1.81.4-1.61.71.61.3-1.21.41.21.51.4-1.20.7-0.1-0.3
Std. dev. reaction times0.31.17.0-0.8-0.70.70.6-0.70.7-0.60.50.6-0.60.50.50.30.90.2-0.7-0.50.01.51.8-2.02.7-0.0-1.4
Reaction time trials completed0.10.20.60.50.5-0.5-0.40.3-0.30.5-0.3-0.30.3-0.4-0.0-0.4-0.4-0.20.40.2-0.2-0.6-0.70.7-0.80.20.4
Reaction time trials AUC0.10.20.60.50.5-0.5-0.40.3-0.30.5-0.3-0.30.3-0.5-0.0-0.4-0.4-0.20.40.2-0.2-0.6-0.70.7-0.80.20.3
Run reversals in cocaine runway, females0.10.20.9-0.40.2-0.30.10.1-0.10.30.3-0.10.1-0.20.5-0.80.1-0.1-0.0-0.4-0.20.40.5-0.60.90.3-0.7
Run reversals in cocaine runway, males0.10.10.2-0.1-0.40.40.2-0.30.3-0.4-0.00.3-0.30.3-0.30.40.30.2-0.20.30.20.10.2-0.10.10.2-0.1
Latency to leave start box in cocaine runway0.40.61.10.70.8-0.7-0.80.8-0.80.9-0.8-0.70.7-0.90.8-0.5-0.7-0.90.9-1.0-0.9-0.6-0.50.50.31.0-0.8
Latency to leave start box in cocaine runway, F0.10.10.3-0.1-0.20.20.1-0.20.2-0.10.10.3-0.30.2-0.50.60.10.3-0.10.30.3-0.0-0.10.2-0.5-0.30.4
Latency to leave start box in cocaine runway, M2.12.02.71.31.5-1.5-1.51.6-1.61.6-1.5-1.61.6-1.51.4-1.4-1.5-1.51.5-1.5-1.5-1.3-1.21.2-0.11.2-0.7
Std. dev. time between licks in bursts0.20.40.7-0.5-0.70.70.6-0.60.6-0.70.60.6-0.60.8-0.60.60.70.7-0.80.60.70.70.8-0.80.3-0.80.4
Total sessions with >9 infusions0.40.53.70.40.2-0.2-0.30.3-0.30.2-0.5-0.30.3-0.1-0.7-0.2-0.40.10.30.80.2-0.9-1.11.3-1.9-0.21.2
Short access day 1 total inactive lever presses0.61.13.50.81.1-1.1-0.91.0-1.01.1-0.9-1.01.0-1.00.2-1.1-1.1-0.71.1-0.0-0.6-1.4-1.71.9-1.80.60.5
Short access day 10 total inactive lever presses0.10.71.00.90.8-0.8-0.90.8-0.80.8-1.0-0.80.8-0.90.9-1.0-0.9-1.01.0-1.0-1.0-0.7-0.60.60.30.9-0.8
Short access day 1 total infusions0.30.64.80.40.3-0.4-0.40.4-0.40.3-0.5-0.40.4-0.2-0.4-0.4-0.50.10.40.70.2-1.1-1.41.5-2.2-0.21.3
Short access day 10 total infusions0.30.53.9-0.00.1-0.1-0.10.1-0.10.1-0.3-0.10.10.0-0.7-0.2-0.20.30.10.90.4-0.8-1.01.2-2.0-0.31.3
Short access total infusions0.40.65.2-0.0-0.20.20.1-0.10.1-0.2-0.10.1-0.10.3-1.00.2-0.10.6-0.01.30.7-0.8-1.01.2-2.3-0.61.6
Short access day 1 locomotion0.71.23.6-0.7-1.11.00.9-1.11.1-1.10.81.0-1.01.0-1.91.00.91.3-0.91.81.30.30.10.1-1.6-0.71.3
Short access day 10 total locomotion0.31.11.8-0.8-1.21.21.1-1.21.2-1.31.01.2-1.21.0-1.31.31.20.9-0.90.90.81.11.1-1.00.5-0.2-0.1
Short access total locomotion0.20.31.7-0.2-0.50.30.3-0.40.4-0.50.20.4-0.40.4-1.30.20.30.6-0.31.00.7-0.1-0.30.4-1.2-0.41.0
One hour access (0.3 mA shock)0.50.61.80.90.6-0.7-0.80.7-0.70.6-1.0-0.60.6-0.70.3-0.4-0.7-0.40.70.0-0.3-1.1-1.21.3-1.30.50.5
Compulsive drug intake0.20.31.00.60.5-0.4-0.40.3-0.30.4-0.2-0.30.3-0.50.90.2-0.3-0.60.3-0.8-0.6-0.00.2-0.41.00.6-1.0
One hour access (shock baseline)0.20.74.40.60.3-0.3-0.50.4-0.40.3-0.8-0.40.4-0.3-0.3-0.3-0.6-0.10.60.70.1-1.2-1.41.7-2.10.11.2
Social response proportion2.53.25.5-2.1-1.81.81.9-1.71.7-1.81.91.7-1.71.9-1.21.72.01.9-2.11.21.72.22.2-2.31.2-1.70.4
Social responses0.60.81.21.11.0-1.0-1.01.1-1.11.0-1.0-1.01.0-0.91.1-1.1-0.9-0.90.8-1.0-0.9-0.7-0.60.50.00.3-0.2
Social time0.30.43.7-0.5-0.20.20.3-0.20.2-0.20.30.1-0.10.7-0.1-0.10.40.8-1.00.20.80.50.6-0.9-0.0-1.91.3
Soleus weight0.51.410.00.60.6-0.6-0.50.6-0.60.6-0.5-0.50.50.2-0.5-0.5-0.80.5-0.21.00.7-1.1-1.41.2-2.7-2.33.2
Bone: stiffness3.15.79.52.62.9-2.9-2.72.5-2.52.9-2.5-2.72.7-2.63.1-2.6-2.5-2.52.1-2.7-2.5-1.8-1.51.20.31.1-1.0
Tibialis anterior weight7.927.335.25.75.9-5.9-5.85.6-5.65.9-5.7-5.65.6-5.75.2-5.5-5.7-5.35.4-4.6-5.2-5.3-5.25.0-1.53.6-1.3
Time to tail flick, vehicle, before self-admin0.40.42.2-0.7-0.70.70.6-0.80.8-0.70.50.8-0.80.5-0.41.50.70.4-0.40.30.40.70.7-0.60.60.2-0.4
Time to tail flick, vehicle, after self-admin0.10.11.20.2-0.10.10.0-0.00.0-0.1-0.00.0-0.0-0.10.41.1-0.0-0.30.3-0.2-0.3-0.10.00.00.30.6-0.5
Time to tail flick, test, before self-admin0.50.50.70.70.8-0.8-0.70.8-0.80.8-0.7-0.80.8-0.80.6-0.9-0.7-0.80.8-0.7-0.8-0.7-0.60.6-0.00.6-0.4
Time to tail flick, test, after self-admin2.32.45.71.31.4-1.5-1.41.3-1.31.4-1.4-1.31.3-1.81.9-1.4-1.2-1.91.7-2.0-2.0-0.7-0.50.51.42.4-2.3
Delta time to tail flick, vehicle, before/after SA0.10.10.30.40.2-0.2-0.30.4-0.40.2-0.2-0.40.4-0.10.6-0.4-0.3-0.30.1-0.3-0.2-0.3-0.10.00.0-0.10.1
Delta time to tail flick, test, before/after SA0.20.21.3-0.2-0.20.20.2-0.30.3-0.20.20.3-0.3-0.10.30.40.3-0.20.1-0.4-0.30.50.6-0.51.00.8-1.1
Tibia length0.20.64.60.20.7-0.7-0.40.0-0.00.6-0.2-0.10.10.0-0.10.1-0.50.5-0.40.80.6-0.5-0.70.5-1.7-1.92.1
Ambulatory time before self-admin1.13.54.92.12.1-2.1-2.12.1-2.12.1-2.2-2.12.1-1.91.6-1.3-2.1-1.71.8-1.2-1.6-2.2-2.22.1-1.30.70.2
Ambulatory time after self-admin0.20.40.70.70.7-0.8-0.80.7-0.70.7-0.9-0.70.7-0.60.7-0.6-0.6-0.50.5-0.6-0.5-0.5-0.50.4-0.1-0.00.1
Bone: tissue strength0.10.10.40.40.4-0.4-0.30.2-0.20.4-0.3-0.40.4-0.10.5-0.2-0.1-0.0-0.2-0.4-0.10.10.2-0.50.3-0.60.1
Total heroin consumption1.21.44.4-0.5-0.91.00.9-1.01.0-0.90.91.0-1.01.2-1.80.80.71.4-1.02.01.50.1-0.20.3-1.8-1.72.1
Bone: trabecular number0.91.72.91.51.2-1.2-1.31.4-1.41.2-1.2-1.51.5-1.41.6-1.4-1.1-1.51.3-1.7-1.5-0.8-0.60.50.91.5-1.5
Bone: trabecular spacing0.10.10.4-0.4-0.20.20.2-0.20.2-0.10.20.2-0.20.10.10.10.20.0-0.1-0.1-0.10.40.4-0.40.60.2-0.5
Bone: trabecular thickness0.10.10.3-0.2-0.50.50.3-0.20.2-0.50.30.3-0.30.4-0.20.30.50.2-0.3-0.00.20.50.6-0.60.6-0.0-0.3
Bone: trabecular tissue density2.23.95.82.12.4-2.4-2.32.4-2.42.4-2.3-2.32.3-2.02.2-2.2-2.1-1.91.7-2.0-1.8-1.8-1.61.3-0.40.4-0.0
Water consumed over 24 hours0.50.91.81.01.0-1.0-0.90.9-0.91.0-0.8-0.90.9-1.21.0-0.8-0.9-1.21.2-0.9-1.2-0.8-0.70.80.31.4-1.1
Number of responses in last shaping day0.91.28.90.10.1-0.1-0.10.2-0.20.1-0.3-0.20.20.3-1.30.2-0.40.7-0.21.40.9-1.0-1.41.5-3.0-1.42.6