Ccdc107

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS NM_001107957.2 0.02 0.02 4.2e-03 0.02 0.01 0.01 0.01 4.6e-03 4.1e-02 1.3e-02 2.6e-02
2 NAcc gene expression Ccdc107 0.05 0.03 4.9e-06 0.04 0.03 0.04 0.04 1.7e-06 2.0e-05 1.7e-06 2.9e-06
3 Brain alternative TSS NM_001107957.2 0.06 0.04 2.4e-06 0.05 0.02 0.05 0.05 1.9e-05 8.2e-03 2.9e-05 2.3e-05
4 pVTA gene expression Ccdc107 0.1 0.06 3.5e-09 0.1 0.1 0.11 0.11 1.8e-08 2.4e-08 3.2e-09 2.0e-09
5 Brain alternative TSS XM_006238137.5 0.07 0.04 3.3e-06 0.04 0.01 0.04 0.04 4.9e-05 2.1e-02 8.8e-05 6.1e-05
6 Liver alternative TSS XM_039109982.2 0.05 0.04 1.9e-05 0.03 0.02 0.03 0.03 2.0e-04 8.9e-04 5.4e-04 6.2e-04
7 NAcc alternative TSS NM_001107957.2 0.03 0.02 3.1e-04 0.03 0.02 0.03 0.03 8.6e-05 1.2e-03 9.5e-05 5.1e-05
8 NAcc alternative TSS XM_039109982.2 0.03 0.02 4.3e-05 0.03 0.02 0.02 0.03 1.6e-05 5.0e-04 1.6e-04 4.6e-05
9 Brain alternative TSS NM_001107957.2 0.08 0.05 2.5e-07 0.07 0.03 0.07 0.07 2.2e-07 6.0e-04 5.7e-07 4.2e-07
10 Brain alternative TSS XM_006238136.5 0.05 0.03 3.6e-04 0.04 0.01 0.03 0.04 9.9e-05 1.5e-02 4.3e-04 1.7e-04
11 Brain mRNA stability Ccdc107 0.09 0.05 5.7e-09 0.08 0.07 0.09 0.09 7.2e-08 1.8e-07 4.8e-09 1.0e-08
12 pVTA mRNA stability Ccdc107 0.07 0.05 4.6e-06 0.06 0.06 0.07 0.07 7.0e-06 6.3e-06 1.9e-06 1.1e-06
13 NAcc mRNA stability Ccdc107 0.03 0.03 1.3e-04 0.04 0.01 0.03 0.04 9.9e-07 1.5e-02 9.3e-06 1.8e-06
14 NAcc alternative TSS XM_006238137.5 0.03 0.02 2.4e-04 0.02 0.03 0.02 0.02 1.5e-04 7.4e-05 1.5e-04 4.6e-04
15 RMTg gene expression Ccdc107 0.11 0.07 3.4e-03 0.06 0.07 0.03 0.06 8.9e-03 6.2e-03 6.3e-02 1.3e-02
16 PL mRNA stability Ccdc107 0.04 0.03 7.7e-07 0.05 0.05 0.04 0.04 1.4e-06 1.9e-06 1.1e-05 1.0e-05
17 NAcc alternative TSS XM_006238137.5 0.02 0.01 1.3e-03 0 0.01 -0 0 7.9e-02 6.5e-03 6.2e-01 6.2e-02
18 Brain gene expression Ccdc107 0.08 0.06 5.2e-06 0.06 0.07 0.06 0.06 2.5e-06 8.4e-07 2.9e-06 4.3e-06
19 Liver gene expression Ccdc107 0.24 0.11 0.0e+00 0.15 0.16 0.16 0.16 6.9e-16 2.4e-17 4.1e-17 2.6e-17
20 Liver alternative TSS NM_001107957.2 0.05 0.03 4.6e-04 0.03 0.03 0.02 0.02 6.4e-04 5.2e-04 1.8e-03 9.9e-04
21 BLA mRNA stability Ccdc107 0.05 0.04 9.0e-03 0.01 0.01 0.02 0.01 7.7e-02 6.7e-02 3.4e-02 1.1e-01
22 Adipose gene expression Ccdc107 0.28 0.11 0.0e+00 0.19 0.19 0.19 0.19 1.3e-20 1.5e-20 2.1e-20 1.2e-20
23 NAcc intron excision ratio chr5_62545739_62547190 0.02 0.03 8.1e-03 0.01 0.01 0.02 0.01 5.0e-03 1.1e-02 8.9e-04 4.4e-03
24 NAcc intron excision ratio chr5_62545739_62547187 0.02 0.02 7.4e-03 0.01 0.01 0.02 0.01 5.4e-03 5.1e-03 4.7e-04 4.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.32.23.8-1.6-1.41.4-1.4-1.51.51.41.31.6-1.61.71.71.5-1.3-1.71.8-1.8-1.0-0.80.81.70.8-1.91.7
Area under the delay curve0.50.61.70.40.7-0.70.60.6-0.6-0.7-0.6-0.60.6-0.8-1.3-0.70.50.8-1.10.90.20.2-0.1-0.7-0.71.0-1.1
BMI with tail1.65.510.4-2.4-2.32.2-2.4-2.32.42.32.32.2-2.22.62.52.4-2.3-2.72.5-2.7-2.0-1.91.93.20.4-2.92.1
BMI without tail2.16.58.7-2.9-2.82.7-2.8-2.62.62.82.72.4-2.42.92.82.7-2.6-2.82.6-2.8-2.3-2.12.13.00.2-2.41.5
Body weight3.415.119.3-4.4-4.34.2-4.3-4.24.24.14.24.1-4.14.23.74.0-4.2-4.03.4-3.9-4.1-4.03.94.1-1.3-3.01.2
Weight adjusted by age0.20.40.9-0.7-0.50.3-0.7-0.60.60.50.80.6-0.60.40.40.6-0.7-0.40.3-0.3-0.8-0.90.90.7-0.6-0.1-0.4
Bone surface0.91.72.2-1.4-1.41.4-1.3-1.41.41.31.21.5-1.51.41.31.3-1.3-1.41.2-1.4-1.2-1.11.11.5-0.0-1.30.8
Bone volume0.71.22.0-1.2-1.11.1-1.1-1.11.11.10.91.2-1.21.31.31.0-1.0-1.31.2-1.3-0.8-0.70.71.30.4-1.41.2
Breakpoint value in progressive ratio session1.21.48.4-0.10.2-0.30.20.3-0.3-0.2-0.1-0.30.3-0.7-1.4-0.00.01.1-1.91.3-0.8-1.11.30.2-2.91.9-2.9
Number of licking bursts3.15.07.2-2.2-2.42.4-2.4-2.32.32.42.32.3-2.32.52.72.3-2.2-2.62.5-2.6-1.8-1.61.62.20.5-2.41.8
Context. condit. distance diff. score0.10.10.20.50.4-0.50.40.4-0.4-0.5-0.4-0.40.4-0.4-0.3-0.30.40.3-0.20.20.40.4-0.4-0.10.4-0.10.3
Locomotion velocity, session 12.22.311.8-1.1-1.11.1-1.1-1.21.21.11.21.2-1.20.7-0.21.2-1.5-0.4-0.3-0.1-2.2-2.52.61.6-3.40.7-2.4
Locomotion distance, session 10.70.93.5-1.0-0.80.8-0.8-0.80.80.90.90.8-0.80.50.10.8-1.0-0.4-0.1-0.2-1.3-1.41.41.0-1.90.4-1.3
Locomotion velocity, session 22.32.64.0-1.8-1.61.5-1.7-1.71.71.51.71.7-1.71.71.91.7-1.5-1.92.0-1.9-1.2-1.00.91.70.6-1.71.5
Locomotion distance, session 22.12.94.3-2.0-2.12.1-2.0-1.81.82.11.91.8-1.81.71.51.8-2.0-1.41.2-1.3-1.9-1.91.71.3-1.3-0.0-0.7
Locomotion velocity, session 30.30.42.6-0.4-0.40.4-0.4-0.40.40.40.40.4-0.40.2-0.30.4-0.60.0-0.40.1-0.9-1.01.00.4-1.60.6-1.2
Locomotion distance, session 32.83.15.9-1.8-1.81.8-1.8-1.71.71.81.81.7-1.71.91.31.7-2.0-1.71.1-1.6-2.1-2.22.22.4-1.3-1.50.3
Stereotopy head waving bouts, day 30.40.43.4-0.10.1-0.10.1-0.10.1-0.1-0.10.1-0.1-0.4-0.70.0-0.10.6-0.70.7-0.5-0.60.6-0.5-1.61.3-1.8
Stereotopy head waving duration, day 30.30.41.50.40.5-0.50.50.3-0.3-0.5-0.5-0.30.3-0.7-0.7-0.30.30.8-0.70.80.10.1-0.1-0.8-0.81.1-1.2
Locomotion velocity, session 70.10.10.10.20.3-0.30.30.3-0.3-0.3-0.3-0.30.3-0.3-0.4-0.30.30.3-0.40.30.30.2-0.2-0.20.00.3-0.2
Locomotion distance, session 70.30.40.7-0.7-0.70.7-0.6-0.60.60.70.50.6-0.60.60.30.6-0.7-0.50.3-0.5-0.7-0.80.80.7-0.7-0.3-0.1
Stereotopy head waving bouts, day 71.51.72.7-1.3-1.21.2-1.3-1.41.41.21.31.4-1.41.31.01.4-1.5-1.31.0-1.2-1.6-1.61.71.5-0.9-1.10.1
Stereotopy head waving duration, day 70.60.71.1-0.9-0.80.9-0.9-1.01.00.91.01.0-1.00.80.71.0-1.0-0.80.8-0.7-1.0-1.01.00.6-0.6-0.4-0.1
Locomotion velocity, session 80.30.42.6-0.2-0.40.3-0.3-0.20.20.40.20.2-0.2-0.1-0.10.3-0.30.3-0.40.4-0.4-0.50.4-0.5-1.31.4-1.6
Locomotion distance, session 80.30.41.4-0.6-0.70.7-0.7-0.60.60.70.60.6-0.60.40.20.7-0.7-0.20.0-0.2-0.9-0.90.90.5-1.20.5-1.0
Degree of sensitization distance1.41.43.71.11.1-1.21.11.1-1.1-1.1-1.2-1.11.1-1.3-1.0-1.01.31.3-0.91.31.31.3-1.4-1.90.41.5-0.7
Degree of sensitization stereotypy1.51.73.0-1.3-1.21.2-1.3-1.31.31.21.31.3-1.31.41.21.2-1.3-1.51.2-1.4-1.3-1.31.41.7-0.2-1.60.8
Conditioned locomotion0.20.21.1-0.2-0.00.0-0.00.0-0.00.00.0-0.10.1-0.0-0.60.1-0.20.1-0.60.2-0.6-0.80.90.8-1.10.1-0.8
Cocaine response after cond. corrected1.51.83.81.41.2-1.21.31.3-1.3-1.2-1.3-1.31.3-1.4-1.8-1.30.91.6-1.91.70.50.2-0.1-0.8-1.81.6-2.0
Cocaine response after cond. not corrected1.41.75.51.21.0-1.01.11.0-1.0-0.9-1.1-1.01.0-1.3-1.7-1.10.71.6-1.71.70.30.0-0.0-1.2-2.02.0-2.3
Cocaine response before conditioning0.60.71.3-0.8-1.01.0-0.9-1.01.01.10.91.0-1.00.91.10.9-0.9-0.81.0-0.8-0.6-0.50.40.20.2-0.20.2
Saline control response0.91.22.8-1.1-1.31.3-1.1-1.11.11.31.01.2-1.21.00.71.0-1.3-0.80.4-0.7-1.4-1.51.51.0-1.70.0-0.8
Bone: connectivity density0.71.12.6-1.3-0.80.8-1.0-1.01.00.80.91.1-1.11.11.21.1-0.7-1.31.4-1.3-0.5-0.40.41.11.0-1.61.6
Bone: cortical apparent density0.20.32.70.20.3-0.30.30.1-0.1-0.2-0.3-0.30.3-0.00.4-0.20.5-0.10.5-0.20.80.9-1.0-0.11.6-0.51.2
Bone: cortical area2.13.25.7-1.7-2.02.0-1.8-1.51.52.01.61.6-1.62.12.41.6-1.5-2.12.3-2.2-1.0-0.70.61.61.4-2.12.2
Bone: cortical porosity0.20.20.40.30.5-0.50.40.4-0.4-0.6-0.3-0.40.4-0.6-0.4-0.20.50.4-0.30.40.40.5-0.5-0.70.20.4-0.2
Bone: cortical porosity0.00.00.1-0.10.0-0.0-0.1-0.10.1-0.10.20.1-0.1-0.0-0.00.2-0.1-0.10.0-0.1-0.2-0.20.20.1-0.2-0.1-0.0
Bone: cortical thickness0.81.35.7-0.6-1.01.0-0.8-0.40.40.90.60.5-0.51.31.50.5-0.5-1.31.5-1.50.10.2-0.31.22.0-1.92.4
Bone: cortical thickness0.40.51.40.80.5-0.50.70.8-0.8-0.5-0.8-0.80.8-0.5-0.2-0.70.80.5-0.30.41.11.1-1.10.11.20.20.4
Bone: cortical tissue density0.20.32.30.30.3-0.30.30.2-0.2-0.3-0.4-0.30.3-0.10.3-0.20.50.00.4-0.10.80.9-1.0-0.21.5-0.31.0
Condit. Reinf. active minus inactive responses0.40.40.9-0.6-0.60.6-0.6-0.90.90.60.70.9-0.90.60.90.9-0.7-0.80.9-0.8-0.5-0.40.30.30.4-0.40.4
Condit. Reinf. active-inactive response ratio0.70.81.21.11.0-1.01.10.9-0.9-0.9-1.1-0.90.9-0.9-0.7-0.91.00.9-0.70.81.01.0-0.9-0.70.50.7-0.2
Condit. Reinf. active responses2.53.15.1-1.8-1.71.7-1.9-2.12.11.82.02.1-2.11.82.22.1-1.8-2.02.3-2.0-1.5-1.21.01.30.6-1.41.1
Condit. Reinf. inactive responses3.13.86.4-2.1-2.12.0-2.2-2.22.22.12.22.2-2.22.02.52.2-1.9-2.22.5-2.2-1.4-1.10.91.30.9-1.61.5
Incentive salience index mean4.35.27.2-2.4-2.32.3-2.5-2.72.72.42.52.7-2.72.32.42.7-2.4-2.52.5-2.4-2.2-2.01.91.8-0.2-1.70.9
Condit. Reinf. lever presses10.614.919.5-4.3-4.14.0-4.3-4.44.44.14.34.3-4.34.03.74.4-4.2-4.03.7-3.9-4.1-3.83.63.2-1.2-2.71.2
Condit. Reinf. active minus inactive responses0.60.81.4-0.8-1.11.1-0.9-0.70.71.00.80.8-0.81.21.10.7-0.8-1.01.0-1.1-0.6-0.50.50.90.4-1.21.2
Condit. Reinf. active-inactive response ratio0.20.21.4-0.2-0.40.4-0.3-0.10.10.30.10.1-0.10.60.50.1-0.1-0.50.5-0.60.00.1-0.10.50.6-1.01.2
Condit. Reinf. active responses2.12.94.3-1.8-2.12.1-1.9-1.71.72.01.81.8-1.82.11.91.7-1.7-1.91.8-1.9-1.5-1.31.21.40.2-1.61.3
Condit. Reinf. inactive responses2.43.14.1-2.0-2.02.0-2.0-1.91.92.02.01.9-1.92.02.01.9-1.7-1.92.0-2.0-1.4-1.21.01.30.7-1.51.2
Condit. Reinf. lever presses2.33.25.6-1.8-1.91.9-1.9-1.81.81.91.81.8-1.82.12.31.7-1.5-2.02.4-2.1-1.0-0.70.51.01.4-1.92.1
Condit. Reinf. lever reinforcers received2.43.45.0-2.0-2.22.2-2.1-1.91.92.12.02.0-2.02.22.01.9-1.8-2.02.0-2.0-1.6-1.41.31.40.2-1.61.3
Conditioned reinforcement - actives0.10.10.4-0.4-0.10.1-0.3-0.10.1-0.00.60.1-0.10.3-0.10.1-0.2-0.2-0.1-0.1-0.5-0.50.60.3-0.6-0.60.0
Conditioned reinforcement - inactives0.20.30.90.40.5-0.50.40.6-0.6-0.5-0.2-0.70.7-0.5-0.9-0.10.40.6-0.90.60.10.00.10.2-0.60.3-0.6
Conditioned locomotion0.30.31.4-0.5-0.20.3-0.5-0.30.30.20.70.3-0.30.5-0.40.0-0.4-0.3-0.2-0.3-0.8-1.01.21.0-1.1-0.9-0.0
Patch foraging indifference point 0 sec0.91.76.8-1.4-0.90.9-1.0-0.90.90.91.20.8-0.80.9-0.41.3-1.3-0.7-0.3-0.4-2.1-2.32.51.7-2.6-0.5-1.1
Patch foraging indifference point AUC8.111.714.9-3.6-3.83.7-3.8-3.93.93.73.83.8-3.83.73.63.6-3.7-3.63.4-3.6-3.4-3.23.12.8-0.8-2.61.3
Delay disc. indifference point, 0s delay0.91.02.30.91.0-1.00.90.8-0.8-1.0-0.9-0.80.8-1.2-1.2-0.70.81.2-1.41.30.50.4-0.4-0.6-0.81.5-1.5
Delay disc. indifference point, 16s delay1.01.13.60.70.8-0.80.90.8-0.8-0.8-0.9-0.80.8-1.1-1.7-0.80.61.2-1.61.30.2-0.10.2-0.5-1.41.5-1.9
Delay disc. indifference point, 2s delay0.10.10.30.1-0.00.0-0.1-0.10.10.00.10.1-0.10.10.10.2-0.0-0.30.3-0.30.10.2-0.20.20.5-0.50.6
Delay disc. indifference point, 24s delay0.10.20.30.30.4-0.40.40.4-0.4-0.4-0.5-0.40.4-0.5-0.3-0.10.40.4-0.40.40.40.4-0.5-0.30.10.6-0.3
Delay disc. indifference point, 4s delay0.10.10.90.30.3-0.30.30.2-0.2-0.3-0.3-0.20.2-0.3-0.6-0.90.20.3-0.50.30.10.1-0.1-0.7-0.20.4-0.4
Delay disc. indifference point, 8s delay0.00.00.2-0.5-0.10.1-0.2-0.10.10.10.20.1-0.10.1-0.10.2-0.1-0.10.1-0.1-0.2-0.10.0-0.3-0.10.1-0.1
Indifference point function ln k2.34.05.32.12.3-2.22.22.2-2.2-2.2-2.2-2.32.3-2.2-2.3-1.92.12.2-2.22.21.81.7-1.6-1.40.21.7-1.2
Indifference point function log k2.34.05.32.12.3-2.22.22.2-2.2-2.2-2.2-2.32.3-2.2-2.3-1.92.12.2-2.22.21.81.7-1.6-1.40.21.7-1.2
Patch foraging total patch changes 0 sec1.32.47.2-1.8-1.21.3-1.4-1.31.31.21.51.2-1.21.30.01.7-1.7-1.10.1-0.9-2.3-2.52.72.0-2.5-1.0-0.7
Patch foraging total patch changes 12 sec2.63.34.8-2.1-1.71.7-1.9-1.81.81.71.91.8-1.82.01.71.9-1.9-2.01.6-2.0-1.8-1.81.82.2-0.2-2.21.3
Patch foraging total patch changes 18 sec0.81.31.9-1.4-1.31.3-1.4-1.21.21.21.41.2-1.21.21.01.2-1.2-1.10.9-1.0-1.3-1.21.20.6-0.7-0.80.3
Patch foraging total patch changes 24 sec2.34.05.2-2.1-2.12.1-2.2-2.12.12.12.22.1-2.12.21.72.0-2.2-2.11.7-2.0-2.3-2.32.31.9-1.0-1.80.7
Patch foraging total patch changes 6 sec3.55.49.2-2.6-2.32.3-2.5-2.42.42.32.62.3-2.32.41.42.5-2.6-2.21.5-2.1-2.9-2.93.02.4-1.9-1.80.3
Patch foraging time to switch 0 sec2.55.26.62.42.4-2.52.42.5-2.5-2.4-2.4-2.52.5-2.4-1.9-2.42.52.3-1.82.22.62.5-2.6-2.41.21.6-0.3
Patch foraging water rate 0 sec1.83.89.5-1.9-1.92.0-1.9-1.91.91.91.91.8-1.82.11.21.8-2.1-1.91.1-1.8-2.4-2.52.73.1-1.3-1.90.4
Patch foraging water rate 12 sec0.00.10.5-0.1-0.30.2-0.1-0.00.00.30.0-0.00.00.1-0.2-0.2-0.3-0.0-0.30.0-0.4-0.50.60.5-0.70.2-0.5
Patch foraging water rate 18 sec0.30.52.3-0.5-0.50.5-0.5-0.30.30.60.40.4-0.40.80.70.4-0.5-0.90.6-1.0-0.3-0.30.41.50.7-1.51.2
Patch foraging water rate 24 sec0.20.32.10.30.3-0.30.30.4-0.4-0.3-0.2-0.40.40.00.2-0.20.4-0.20.3-0.30.70.7-0.60.41.4-0.81.2
Patch foraging water rate 6 sec0.50.71.7-0.5-1.01.1-0.8-0.80.81.00.70.9-0.91.01.00.6-0.9-0.80.6-0.8-0.7-0.80.81.3-0.2-0.50.2
Seeking ratio, delayed vs. immediate footshock3.34.07.6-2.8-1.81.9-2.2-2.02.02.02.32.0-2.02.12.01.5-2.0-2.42.0-2.3-2.0-1.81.82.00.2-2.31.7
Distance traveled before self-admin3.24.26.4-2.2-2.42.4-2.4-2.42.42.42.52.4-2.42.11.81.4-2.3-1.91.6-1.8-2.3-2.32.21.1-1.2-0.8-0.1
Distance traveled after self-admin0.70.81.9-0.8-1.11.1-1.1-1.01.01.11.11.0-1.01.01.20.7-0.8-1.01.4-1.1-0.4-0.20.1-0.00.8-0.70.9
Extensor digitorum longus weight5.019.826.5-5.1-4.84.8-5.0-4.84.84.85.04.6-4.64.94.44.9-4.7-4.84.2-4.7-4.4-4.14.04.5-0.6-3.71.9
Bone: elastic displacement5.66.48.83.02.8-2.82.82.9-2.9-2.8-2.8-2.92.9-2.5-2.4-2.82.92.4-2.32.32.82.7-2.5-1.61.41.10.0
Bone: elastic work3.14.08.52.12.0-2.02.12.2-2.2-2.0-2.2-2.22.2-1.5-1.0-2.12.31.3-0.91.12.72.8-2.7-1.02.9-0.31.8
Bone: endosteal estimation1.32.84.0-1.7-1.91.9-1.8-1.91.91.91.82.0-2.01.61.71.8-1.9-1.61.3-1.5-1.8-1.81.71.3-1.1-0.6-0.1
Bone: endosteal perimeter1.32.84.0-1.8-1.91.9-1.8-1.71.71.91.81.9-1.91.71.41.8-2.0-1.61.2-1.5-2.0-2.01.91.5-1.4-0.8-0.2
Epididymis fat weight0.31.12.0-1.0-1.11.0-1.1-1.21.21.11.11.2-1.21.01.41.2-1.0-1.21.4-1.2-0.8-0.60.50.80.5-0.70.7
Delta time in closed arm before/after self-admin0.40.41.8-0.4-0.40.4-0.5-0.30.30.40.50.4-0.40.61.1-0.1-0.2-0.71.0-0.80.10.3-0.4-0.11.2-0.91.3
Delta time in open arm before/after self-admin0.30.31.0-0.30.4-0.30.30.4-0.4-0.4-0.3-0.40.4-0.5-1.00.00.30.6-0.80.7-0.1-0.10.1-0.5-0.90.8-1.0
Diff in mean of infusions in LGA sessions0.20.31.00.60.4-0.40.40.5-0.5-0.4-0.4-0.50.5-0.40.2-0.10.60.40.10.30.80.9-1.0-0.70.90.30.3
Delay discount exponential model param0.40.41.5-0.3-0.60.6-0.5-0.50.50.60.60.5-0.50.71.20.6-0.4-0.71.0-0.8-0.1-0.10.10.70.7-0.91.0
Extinction: sum of active levers before priming3.33.66.31.32.1-2.11.92.0-2.0-1.9-1.8-2.02.0-2.3-2.5-1.31.82.2-2.42.31.41.3-1.3-1.8-0.62.3-1.9
Active lever presses in extinction session 60.20.20.40.20.5-0.50.40.6-0.6-0.5-0.4-0.60.6-0.5-0.6-0.50.50.5-0.60.50.30.2-0.2-0.1-0.20.3-0.4
Bone: final force1.32.03.9-1.6-1.91.9-1.7-1.41.41.81.41.6-1.61.72.01.5-1.5-1.51.6-1.6-1.0-0.90.60.60.3-0.70.8
Bone: final moment1.01.63.5-1.4-1.71.7-1.5-1.21.21.61.21.3-1.31.51.91.2-1.2-1.41.5-1.4-0.7-0.60.30.40.6-0.70.9
Food consumed during 24 hour testing period0.60.91.5-1.1-1.21.2-1.1-1.01.01.20.91.0-1.01.00.91.0-1.1-0.90.7-0.8-1.0-1.00.90.7-0.6-0.2-0.3
Glucose2.84.55.7-2.2-2.32.3-2.3-2.22.22.32.42.1-2.12.32.12.3-2.3-2.32.0-2.2-2.1-2.02.02.3-0.4-1.90.9
Heart weight0.61.01.9-1.4-1.21.2-1.2-1.11.11.21.11.1-1.11.01.01.0-1.1-1.11.1-1.0-1.0-0.80.60.3-0.0-0.50.3
Delay discount hyperbolic model param0.20.31.1-0.2-0.40.4-0.3-0.40.40.40.40.4-0.40.51.00.5-0.3-0.50.8-0.60.00.0-0.10.50.7-0.80.9
Intermittent access intake day 1-15 change0.40.81.8-0.8-0.70.7-0.8-0.90.90.71.00.8-0.80.91.20.6-0.7-1.11.1-1.1-0.5-0.40.41.00.6-1.31.2
Intermittent access intake escalation0.30.61.5-0.6-0.60.6-0.7-0.70.70.60.80.7-0.70.81.20.4-0.6-0.91.1-1.0-0.3-0.20.20.70.8-1.21.2
Intermittent access intake escalation 20.91.04.0-0.6-0.60.6-0.7-0.70.70.60.70.7-0.71.01.50.4-0.5-1.21.5-1.3-0.10.0-0.10.91.5-1.82.0
Intermitt. access day 1 inactive lever presses0.41.73.9-1.5-1.41.4-1.4-1.31.31.31.41.3-1.31.31.12.0-1.4-1.31.0-1.2-1.3-1.31.31.9-0.5-0.80.2
Intermitt. access day 15 inactive lever presses0.00.10.2-0.5-0.10.0-0.3-0.10.10.10.40.1-0.1-0.00.2-0.1-0.3-0.2-0.0-0.1-0.4-0.40.40.3-0.40.3-0.4
Intermitt. access escalation Index0.50.71.5-0.5-0.90.8-0.9-1.01.00.91.11.0-1.00.70.61.2-0.9-0.60.7-0.6-0.8-0.80.80.8-0.6-0.2-0.1
Intermittent access day 1 total infusions0.81.33.60.71.3-1.31.01.1-1.1-1.3-0.8-1.21.2-1.2-1.9-0.90.91.3-1.91.40.1-0.10.3-0.1-1.60.8-1.5
Intermittent access day 15 total infusions0.10.10.9-0.30.1-0.1-0.2-0.10.1-0.10.40.0-0.00.20.10.0-0.1-0.30.1-0.3-0.3-0.30.40.8-0.1-0.90.5
Intermittent access terminal intake (last 3 days)0.20.21.7-0.4-0.00.0-0.3-0.20.20.00.40.2-0.20.30.20.4-0.2-0.40.0-0.4-0.5-0.50.71.3-0.4-1.00.4
Intermittent access total infusions0.20.31.4-0.5-0.00.1-0.3-0.20.20.10.50.2-0.20.3-0.10.4-0.3-0.3-0.2-0.2-0.8-0.81.01.2-0.9-0.8-0.0
Intermittent access day 1 locomotion0.70.93.50.51.1-1.00.91.0-1.0-1.1-0.8-1.01.0-0.9-1.9-0.70.81.0-1.61.10.1-0.00.3-0.1-1.30.5-1.1
Intermittent access day 15 total locomotion0.40.82.40.51.0-0.90.81.1-1.1-1.0-0.7-1.11.1-0.8-1.3-1.10.80.9-1.61.00.30.10.20.1-0.90.2-0.7
Intermittent access total locomotion1.01.22.10.91.4-1.31.21.4-1.4-1.4-1.0-1.41.4-1.1-1.5-1.31.21.0-1.31.00.80.7-0.5-0.2-0.20.0-0.2
Intermittent access standard deviation0.20.41.1-0.9-0.40.5-0.6-0.50.50.50.70.4-0.40.60.30.3-0.6-0.70.4-0.6-0.8-0.70.81.1-0.3-0.90.4
Left kidney weight0.62.94.5-2.1-2.12.1-2.0-1.81.82.02.01.8-1.81.61.31.7-2.0-1.41.0-1.3-2.0-2.01.91.1-1.6-0.1-0.7
Right kidney weight0.41.83.0-1.7-1.71.7-1.7-1.51.51.71.61.4-1.41.51.41.6-1.4-1.31.4-1.3-1.3-1.10.90.3-0.4-0.50.2
Cocaine induced anxiety0.10.20.60.80.4-0.40.50.4-0.4-0.4-0.6-0.40.4-0.5-0.4-0.50.40.5-0.30.50.50.5-0.5-0.20.10.6-0.3
Post-drug Anxiety0.50.61.0-0.8-1.00.9-0.8-1.01.00.90.71.0-1.00.60.60.9-0.8-0.50.6-0.4-0.7-0.70.60.3-0.60.5-0.6
Baseline Anxiety0.60.71.6-1.3-0.90.9-1.0-0.90.91.01.00.9-0.90.90.91.1-0.9-0.91.0-0.8-0.7-0.50.4-0.20.1-0.20.2
Tail length1.76.710.0-3.0-3.23.1-3.1-2.92.93.02.92.9-2.92.83.02.7-2.8-2.62.6-2.6-2.4-2.32.01.5-0.4-1.20.5
Length with tail1.77.410.6-3.3-3.23.1-3.1-3.03.03.03.03.0-3.02.72.32.9-3.1-2.51.9-2.3-3.2-3.13.02.1-2.0-1.0-0.4
Length without tail0.20.73.6-0.8-0.50.5-0.6-0.60.60.50.60.8-0.80.3-0.20.4-0.8-0.2-0.3-0.0-1.2-1.41.40.6-1.90.3-1.2
Times rat made contact with spout0.40.41.2-0.6-0.50.5-0.5-0.50.50.50.50.5-0.50.70.80.5-0.4-0.80.7-0.8-0.2-0.20.21.00.7-1.11.1
Lifetime Intake0.30.42.3-0.5-0.10.1-0.3-0.20.20.10.60.2-0.20.3-0.30.2-0.4-0.1-0.5-0.0-0.9-1.11.31.0-1.5-0.5-0.6
Liver weight, left0.10.10.6-0.0-0.00.10.00.1-0.10.0-0.10.1-0.1-0.2-0.20.20.00.3-0.20.30.00.0-0.1-0.7-0.40.8-0.7
Liver weight, right0.81.52.21.21.3-1.31.21.4-1.4-1.4-1.2-1.51.5-1.3-1.2-1.51.31.2-1.21.11.21.2-1.1-0.90.50.8-0.3
Locomotor activity0.00.00.3-0.1-0.00.0-0.1-0.10.10.10.10.1-0.1-0.1-0.00.5-0.00.00.10.0-0.00.0-0.0-0.0-0.10.3-0.2
Locomotor testing distance0.20.31.80.30.3-0.30.30.2-0.2-0.2-0.2-0.30.3-0.5-0.70.10.10.6-0.70.7-0.1-0.20.2-0.4-1.11.2-1.3
Locomotor testing rearing0.50.91.7-1.1-1.11.1-1.1-1.21.11.21.11.2-1.20.80.91.3-1.1-0.70.7-0.7-1.0-1.00.90.6-0.70.2-0.6
Locomotion in novel chamber0.40.50.90.70.7-0.60.70.8-0.8-0.8-0.7-0.70.7-0.4-0.6-0.80.80.4-0.20.30.91.0-0.9-0.90.9-0.50.8
Locomotion in novel chamber post-restriction0.81.44.4-0.8-1.11.1-1.0-1.01.01.01.01.1-1.11.32.10.4-0.7-1.41.8-1.5-0.20.1-0.20.21.6-1.51.9
Fecal boli incidents, locomotor time 10.71.01.80.71.3-1.41.01.1-1.1-1.3-1.0-1.11.1-1.2-1.0-0.71.10.8-0.80.81.01.1-1.1-1.00.70.6-0.1
Change in fecal boli incidents, locomotor task1.01.02.3-0.7-1.11.1-1.0-1.11.11.21.11.1-1.11.00.80.9-1.1-0.80.6-0.7-1.1-1.31.41.5-1.0-0.70.0
Time >=10cm from walls, locomotor time 10.30.31.3-0.3-0.50.5-0.3-0.30.30.40.30.3-0.30.3-0.30.4-0.5-0.1-0.30.0-0.7-0.90.90.9-1.20.2-0.8
Bouts of movement, locomotor time 11.92.13.01.61.7-1.71.61.5-1.5-1.7-1.5-1.51.5-1.7-1.5-1.31.51.5-1.31.51.41.4-1.4-1.70.31.2-0.6
Total resting periods, locomotor time 12.62.93.81.91.9-1.91.91.8-1.8-1.9-1.8-1.81.8-1.9-1.5-1.71.81.7-1.31.61.81.8-1.8-1.90.81.1-0.3
Rest time, locomotor task time 12.32.96.72.01.7-1.71.71.6-1.6-1.8-1.7-1.61.6-1.5-0.3-1.51.81.1-0.00.92.32.5-2.6-2.22.40.21.2
Distance moved, locomotor task time 12.13.26.2-2.0-1.91.9-1.8-1.91.91.91.82.0-2.01.60.91.6-2.0-1.30.5-1.2-2.2-2.42.52.2-2.1-0.5-0.8
Vertical activity count, locomotor time 10.92.36.6-1.5-1.31.4-1.4-1.61.61.51.41.6-1.60.90.41.2-1.7-0.7-0.3-0.5-2.0-2.22.21.5-2.60.5-1.8
Time >=10cm from walls, locomotor time 20.10.10.3-0.6-0.30.3-0.4-0.40.30.40.50.3-0.30.20.30.0-0.4-0.20.1-0.1-0.5-0.40.4-0.2-0.40.3-0.4
Bouts of movement, locomotor time 20.40.61.2-1.1-0.70.7-0.9-0.80.90.81.00.8-0.80.70.20.9-0.8-0.80.8-0.8-0.9-0.80.7-0.1-0.2-0.60.3
Total resting periods, locomotor time 20.10.20.5-0.7-0.30.3-0.5-0.40.40.40.60.4-0.40.4-0.00.7-0.4-0.50.4-0.4-0.5-0.40.4-0.2-0.0-0.50.3
Rest time, locomotor task time 20.91.12.51.61.1-1.11.31.1-1.1-1.2-1.3-1.11.1-1.0-0.7-1.11.21.0-0.80.91.31.2-1.1-0.70.70.30.1
Distance moved, locomotor task time 20.30.41.1-0.7-0.50.6-0.6-0.70.70.60.60.7-0.70.51.00.2-0.5-0.70.9-0.7-0.3-0.1-0.1-0.30.6-0.10.5
Vertical activity count, locomotor time 20.40.61.2-1.1-0.80.8-0.9-1.11.00.90.81.1-1.10.51.00.3-0.9-0.60.4-0.5-0.8-0.80.6-0.2-0.60.5-0.6
Light reinforcement 11.22.911.3-1.8-1.71.7-1.6-1.31.41.71.51.3-1.31.00.11.7-1.9-0.6-0.2-0.3-2.3-2.52.41.1-3.41.3-2.7
Light reinforcement 21.42.112.2-1.2-1.01.0-1.0-1.01.01.01.11.1-1.10.3-0.21.3-1.30.0-0.70.3-1.8-2.12.10.3-3.51.6-3.0
Bone: marrow area1.32.94.2-1.8-1.91.9-1.9-1.91.91.91.82.0-2.01.71.81.8-1.9-1.71.5-1.6-1.8-1.71.61.3-0.8-0.80.1
Bone: maximum diameter2.24.16.5-2.2-2.22.2-2.2-2.12.12.22.22.2-2.22.32.52.1-2.0-2.32.4-2.4-1.6-1.41.21.60.6-1.91.7
Bone: maximum force2.74.77.7-2.4-2.72.7-2.5-2.22.22.62.22.3-2.32.52.82.3-2.2-2.42.5-2.4-1.7-1.41.21.50.5-1.51.4
Bone: maximum moment2.13.76.6-2.2-2.42.4-2.2-1.91.92.31.92.0-2.02.22.62.0-1.9-2.12.3-2.2-1.3-1.10.81.20.7-1.41.5
Mean time between licks in bursts0.40.93.40.80.7-0.70.70.7-0.7-0.7-0.7-0.70.7-1.0-0.5-0.70.91.1-0.71.11.11.1-1.3-1.80.31.7-0.9
Mean num. licks in bursts1.62.53.21.61.8-1.81.71.6-1.6-1.8-1.7-1.61.6-1.8-1.7-1.61.71.7-1.71.71.51.4-1.4-1.50.21.4-0.9
Cd content in liver0.80.91.6-0.8-1.31.3-1.0-1.01.01.20.81.1-1.11.01.21.0-1.1-0.80.8-0.8-0.9-0.90.80.7-0.5-0.2-0.1
Co content in liver0.50.62.10.70.5-0.50.70.8-0.8-0.5-0.7-0.60.6-0.8-0.9-0.70.41.0-1.31.00.30.1-0.1-0.4-1.01.4-1.5
Cu content in liver2.02.43.31.81.6-1.61.71.6-1.6-1.6-1.8-1.51.5-1.7-1.3-1.71.61.7-1.31.61.71.6-1.7-1.70.51.7-0.9
Fe content in liver1.11.34.50.90.7-0.70.91.1-1.1-0.7-1.0-1.01.0-1.1-1.3-1.10.71.4-1.71.50.60.4-0.4-1.3-1.12.1-2.0
K content in liver0.20.20.80.40.3-0.30.40.3-0.3-0.3-0.4-0.30.3-0.5-0.7-0.40.20.6-0.70.60.0-0.10.1-0.5-0.90.7-0.9
Mg content in liver0.50.51.00.71.0-1.00.80.7-0.7-1.0-0.7-0.80.8-0.8-0.9-0.80.70.8-0.90.80.50.4-0.4-0.7-0.30.3-0.3
Mn content in liver0.91.02.2-0.9-1.01.0-1.0-1.01.01.01.00.9-0.91.11.40.8-0.8-1.21.5-1.3-0.5-0.30.20.30.8-1.31.4
Na content in liver2.22.34.61.71.3-1.31.51.6-1.6-1.3-1.6-1.41.4-1.7-1.1-1.61.51.7-1.41.71.61.6-1.7-1.80.32.2-1.3
Rb content in liver5.86.89.93.02.5-2.52.83.0-3.0-2.5-2.9-2.92.9-2.7-2.6-3.12.52.8-3.02.82.42.1-2.0-2.6-0.22.4-1.7
Se content in liver2.22.65.2-1.9-1.51.5-1.7-1.91.91.51.81.8-1.81.61.92.0-1.4-1.72.3-1.7-1.2-0.90.70.90.6-1.31.2
Sr content in liver0.90.81.7-1.3-0.70.7-1.0-1.31.30.61.31.3-1.30.60.61.3-0.8-0.71.0-0.6-0.9-0.70.60.1-0.3-0.30.1
Zn content in liver0.00.00.2-0.1-0.20.2-0.1-0.10.10.20.00.3-0.30.10.40.1-0.1-0.10.3-0.20.10.2-0.3-0.30.30.00.2
Bone: minimum diameter0.00.10.40.20.1-0.10.20.2-0.2-0.2-0.2-0.10.1-0.10.2-0.20.2-0.00.3-0.10.40.4-0.4-0.10.7-0.30.6
Time in familiar zone, hab. session 11.31.36.40.91.0-1.00.90.9-0.9-0.9-0.9-0.90.9-0.40.0-0.81.20.10.3-0.11.51.6-1.50.02.5-1.32.3
Time in novel zone, hab. session 12.22.211.00.80.7-0.80.80.9-0.9-0.8-0.8-0.90.9-1.5-1.7-0.90.61.7-1.91.90.2-0.0-0.1-2.0-2.33.1-3.3
Total zone transitions, hab. session 10.00.00.1-0.2-0.10.1-0.1-0.10.10.10.20.1-0.1-0.00.10.1-0.0-0.00.2-0.0-0.00.1-0.1-0.10.10.3-0.1
Total locomotion distance, hab. session 10.40.52.1-0.5-0.50.5-0.5-0.60.60.50.60.6-0.60.61.10.6-0.2-0.71.3-0.80.10.4-0.50.11.4-0.81.3
Locomotion velocity, hab. session 11.42.04.2-1.4-1.41.4-1.4-1.51.51.31.51.5-1.51.51.91.5-1.1-1.62.1-1.6-0.8-0.50.30.81.1-1.41.5
Time in familiar zone, hab. session 21.21.23.11.01.2-1.11.11.0-1.0-1.1-1.1-1.01.0-0.9-0.4-1.11.30.7-0.20.61.51.6-1.6-1.01.80.01.0
Time in novel zone, hab. session 21.21.24.50.90.7-0.80.80.9-0.9-0.8-0.8-0.90.9-1.1-1.5-0.90.61.3-1.71.40.1-0.20.2-0.6-1.81.7-2.1
Total zone transitions, hab. session 20.70.91.4-1.1-1.01.0-1.0-1.01.01.01.01.0-1.00.80.61.0-1.1-0.70.5-0.6-1.2-1.21.10.7-1.1-0.0-0.5
Total locomotion distance, hab. session 20.81.01.4-1.1-1.11.1-1.1-1.21.21.11.11.2-1.21.01.21.2-1.0-1.11.2-1.1-0.9-0.80.71.0-0.0-0.70.5
Locomotion velocity, hab. session 21.11.41.9-1.3-1.21.2-1.3-1.41.41.21.21.4-1.41.21.41.4-1.2-1.31.4-1.3-1.0-0.90.81.20.1-1.00.7
Novel to familiar place preference ratio3.03.36.01.71.7-1.81.71.8-1.8-1.8-1.7-1.81.8-2.0-2.3-1.91.52.1-2.52.21.00.8-0.7-1.7-1.32.2-2.2
Novelty place preference4.14.47.52.12.1-2.12.12.2-2.2-2.2-2.1-2.22.2-2.3-2.6-2.21.92.4-2.72.51.41.1-1.0-2.0-1.12.3-2.2
Time in novel zone, NPP test5.25.59.12.42.3-2.42.42.5-2.5-2.4-2.3-2.52.5-2.6-2.9-2.52.12.7-3.02.81.61.3-1.2-2.3-1.22.7-2.5
Total zone transitions, NPP test0.91.22.0-1.3-1.21.2-1.2-1.21.21.21.31.2-1.20.90.71.2-1.3-0.80.6-0.7-1.4-1.41.30.7-1.40.2-0.8
Total locomotion distance, NPP test2.33.14.3-1.9-1.81.8-1.9-2.02.01.81.92.0-2.01.71.42.0-2.0-1.61.4-1.6-2.1-2.02.01.8-1.3-0.9-0.1
Locomotion velocity, NPP test2.84.05.0-2.2-2.02.1-2.1-2.22.22.02.22.2-2.22.11.82.2-2.2-2.01.8-1.9-2.2-2.12.12.1-1.0-1.40.4
Intraocular pressure2.94.25.8-2.0-2.32.2-2.2-2.22.22.12.22.1-2.12.21.82.1-2.3-2.11.6-2.0-2.3-2.32.32.4-1.0-1.70.5
Delta distance traveled before/after self-admin0.30.30.90.70.4-0.40.50.5-0.5-0.5-0.6-0.50.5-0.5-0.20.20.60.4-0.00.30.80.9-0.9-0.40.80.20.3
Delta ambulatory time before/after self-admin0.91.12.31.31.0-1.01.11.1-1.1-1.1-1.1-1.11.1-1.1-0.6-0.31.21.0-0.50.91.41.4-1.5-1.10.90.8-0.0
Parametrial fat weight0.10.32.20.2-0.10.10.00.2-0.20.1-0.1-0.30.3-0.3-0.5-0.60.00.6-0.80.7-0.1-0.20.2-0.8-1.11.3-1.5
Pavlov. Cond. lever latency6.98.711.43.33.1-3.13.23.4-3.4-3.1-3.3-3.33.3-3.1-2.9-3.33.13.1-2.93.03.02.8-2.7-2.30.72.2-1.1
Pavlov. Cond. magazine entry latency0.50.61.0-1.0-0.90.9-0.9-1.01.00.90.90.9-0.90.80.91.0-0.8-0.81.0-0.8-0.6-0.50.40.10.1-0.30.4
Pavlov. Cond. change in total contacts2.83.04.0-1.9-1.81.8-1.9-2.02.01.81.92.0-2.01.81.71.9-1.9-1.81.7-1.8-1.8-1.71.71.4-0.5-1.20.5
Pavlov. Cond. index score3.13.95.4-2.3-2.12.1-2.2-2.32.32.12.32.2-2.22.12.22.3-2.0-2.12.2-2.1-1.8-1.61.41.1-0.0-1.41.0
Pavlov. Cond. latency score2.93.75.0-2.2-2.02.0-2.1-2.22.22.02.22.2-2.22.02.12.2-2.0-2.02.1-2.0-1.8-1.61.51.1-0.1-1.40.9
Pavlov. Cond. lever contacts6.47.69.9-3.1-2.92.9-3.0-3.13.12.93.13.1-3.12.92.83.1-2.9-2.92.8-2.9-2.7-2.52.42.2-0.4-2.21.3
Pavlov. Cond. magazine entry number0.60.81.31.01.0-1.01.01.0-1.0-1.0-1.0-1.01.0-1.0-1.1-1.00.91.0-1.11.00.60.5-0.4-0.5-0.40.7-0.7
Pavlov. Cond. intertrial magazine entries0.20.20.5-0.5-0.40.4-0.5-0.60.60.40.50.7-0.70.40.60.6-0.5-0.50.6-0.5-0.4-0.30.20.20.2-0.20.1
Pavlov. Cond. lever-magazine prob. diff.3.03.75.4-2.2-2.02.0-2.1-2.32.32.02.22.2-2.22.02.22.2-1.9-2.12.3-2.1-1.7-1.41.21.10.2-1.51.2
Pavlov. Cond. response bias3.94.86.4-2.5-2.42.4-2.4-2.52.52.42.42.5-2.52.32.32.5-2.3-2.32.3-2.3-2.1-1.91.71.5-0.2-1.50.9
Pavlov. Cond. lever latency2.23.05.11.81.9-1.91.91.8-1.8-1.8-1.8-1.91.9-1.9-2.2-1.71.52.0-2.32.01.10.7-0.6-1.0-1.21.7-1.8
Pavlov. Cond. magazine entry latency0.50.51.70.60.6-0.60.60.7-0.7-0.6-0.6-0.60.6-0.7-0.4-0.80.80.7-0.40.61.01.1-1.2-1.30.70.8-0.0
Pavlov. Cond. change in total contacts0.61.04.5-0.7-0.80.8-0.8-0.70.70.80.70.7-0.70.91.50.5-0.3-1.01.6-1.10.30.6-0.8-0.22.1-1.01.9
Pavlov. Cond. index score0.30.42.2-0.3-0.40.4-0.4-0.30.30.40.30.4-0.40.50.90.1-0.0-0.50.9-0.60.40.6-0.8-0.51.5-0.41.2
Pavlov. Cond. latency score0.40.52.6-0.4-0.50.5-0.5-0.40.40.50.40.4-0.40.61.00.2-0.1-0.61.1-0.80.30.6-0.7-0.21.6-0.71.5
Pavlov. Cond. lever contacts1.62.24.1-1.5-1.61.6-1.6-1.61.61.61.61.6-1.61.72.01.4-1.2-1.72.0-1.7-0.8-0.50.30.61.2-1.41.6
Pavlov. Cond. magazine entry number0.30.42.8-0.10.1-0.10.1-0.10.1-0.1-0.00.0-0.0-0.2-0.70.2-0.30.2-0.70.3-0.8-1.01.10.6-1.70.4-1.3
Pavlov. Cond. intertrial magazine entries0.40.51.4-0.6-0.70.7-0.7-0.60.60.70.70.6-0.60.80.60.7-0.8-0.80.5-0.8-0.8-0.90.91.2-0.4-1.00.4
Pavlov. Cond. lever-magazine prob. diff.0.30.42.5-0.2-0.40.4-0.3-0.30.30.40.30.3-0.30.51.00.10.0-0.50.9-0.60.50.7-0.9-0.51.6-0.51.3
Pavlov. Cond. response bias0.70.92.2-0.9-1.01.0-1.0-0.90.91.00.91.0-1.01.01.40.7-0.6-1.01.4-1.1-0.10.2-0.3-0.11.5-0.81.4
Time in closed arm before self-admin0.30.31.00.80.6-0.50.70.7-0.7-0.6-0.9-0.70.7-0.4-1.0-0.80.60.5-0.60.40.50.4-0.30.00.1-0.10.2
Time in closed arm after self-admin0.50.61.81.10.6-0.50.70.7-0.7-0.7-0.7-0.70.7-0.40.1-1.10.80.30.10.21.01.1-1.1-0.61.4-0.41.0
Time in open arm before self-admin1.31.42.2-1.3-1.31.2-1.3-1.41.41.31.41.4-1.41.01.21.5-1.3-0.90.7-0.8-1.4-1.41.31.0-1.1-0.1-0.5
Time in open arm after self-admin1.41.53.4-1.8-1.21.1-1.3-1.31.31.21.31.2-1.21.00.51.6-1.3-1.00.4-0.8-1.6-1.71.71.2-1.4-0.5-0.4
Bone: periosteal estimation1.63.55.4-1.9-2.22.2-2.1-1.91.92.21.92.1-2.12.12.31.9-2.0-2.02.0-2.1-1.6-1.41.31.50.1-1.41.1
Bone: periosteal perimeter0.61.11.6-1.1-1.31.3-1.2-0.90.91.21.11.1-1.11.11.01.1-1.2-1.00.8-1.0-1.1-1.11.11.0-0.6-0.60.1
Bone: post-yield work2.43.54.9-2.2-2.12.1-2.1-2.12.12.12.12.2-2.21.81.82.2-2.2-1.71.6-1.6-2.1-2.01.91.2-1.2-0.6-0.2
Progressive ratio test 1 active lever presses0.50.63.50.20.6-0.60.40.5-0.5-0.6-0.2-0.50.5-0.5-1.1-0.40.20.6-1.40.7-0.5-0.81.10.9-1.90.0-1.1
Progressive ratio test 1 breakpoint0.40.53.10.10.5-0.50.30.4-0.4-0.5-0.1-0.40.4-0.4-1.0-0.30.20.5-1.20.6-0.6-0.81.10.9-1.7-0.1-1.0
Progressive ratio test 1 inactive lever presses1.21.74.5-1.3-1.21.2-1.3-1.21.21.11.41.2-1.21.00.31.3-1.4-0.70.1-0.6-1.8-2.02.01.5-2.1-0.1-1.1
Progressive ratio test 2 active lever presses0.60.73.90.30.7-0.70.40.6-0.6-0.7-0.1-0.70.7-0.7-1.3-0.40.40.9-1.61.0-0.4-0.60.80.1-2.00.5-1.5
Progressive ratio test 2 breakpoint0.70.84.00.40.8-0.80.50.6-0.6-0.8-0.2-0.70.7-0.7-1.4-0.50.40.9-1.71.1-0.3-0.60.80.0-2.00.6-1.6
Progressive ratio test 2 inactive lever presses0.20.31.0-0.7-0.30.3-0.5-0.30.30.20.70.3-0.30.40.30.6-0.4-0.4-0.0-0.3-0.7-0.80.91.0-0.8-0.6-0.1
Incentive Sensitization - Responses0.30.41.30.40.5-0.50.30.5-0.5-0.5-0.0-0.60.6-0.6-0.9-0.40.40.7-1.20.80.0-0.10.2-0.2-1.00.7-1.1
Incentive Sensitization - Breakpoint0.30.41.40.40.5-0.60.40.6-0.6-0.6-0.1-0.60.6-0.6-0.9-0.50.40.7-1.20.80.0-0.10.2-0.2-1.00.7-1.1
Sum of active levers in priming session hrs 5-62.62.45.31.21.6-1.71.51.5-1.5-1.6-1.4-1.61.6-1.8-2.3-0.91.31.9-2.32.00.70.5-0.3-0.7-1.41.9-2.0
Progressive ratio0.00.00.2-0.3-0.10.1-0.10.1-0.10.20.10.0-0.00.0-0.20.3-0.10.0-0.20.1-0.2-0.20.10.0-0.40.3-0.4
Food seeking constrained by brief footshock8.610.514.8-3.8-3.53.6-3.6-3.53.53.53.63.5-3.53.42.13.4-3.6-3.12.2-2.9-3.8-3.83.83.4-2.1-2.20.3
Seeking ratio, punishment vs. effort1.92.73.6-1.6-1.81.8-1.8-1.91.91.81.81.9-1.91.81.41.6-1.8-1.71.5-1.6-1.7-1.71.81.7-0.6-1.40.6
Retroperitoneal fat weight0.52.03.01.41.4-1.41.41.6-1.6-1.4-1.5-1.51.5-1.4-1.0-1.61.51.3-1.01.21.71.7-1.7-1.41.11.1-0.2
Reaction time number correct0.10.30.7-0.6-0.60.6-0.5-0.40.40.60.40.4-0.40.60.00.5-0.5-0.3-0.1-0.3-0.7-0.80.80.8-0.8-0.3-0.3
Reaction time mean minus median0.40.96.8-0.3-0.10.1-0.3-0.10.10.20.30.1-0.10.41.20.50.2-0.71.3-0.90.81.1-1.3-0.22.6-1.12.2
Reaction time mean minus median AUC0.41.13.9-0.8-0.80.8-0.9-0.70.60.80.90.7-0.71.01.51.0-0.5-1.21.5-1.30.10.4-0.60.22.0-1.31.9
Reaction time num false alarms0.10.10.6-0.3-0.10.1-0.1-0.10.1-0.00.00.1-0.10.10.40.10.0-0.20.4-0.30.20.4-0.5-0.30.8-0.20.4
Reaction time num false alarms AUC0.30.41.1-1.0-0.70.7-0.8-0.70.70.70.70.7-0.70.70.80.7-0.7-0.80.6-0.8-0.6-0.50.40.50.1-0.60.3
Reaction time trials correct on left0.10.30.7-0.6-0.60.6-0.5-0.40.40.60.40.4-0.40.60.00.5-0.5-0.3-0.1-0.3-0.7-0.80.80.8-0.8-0.3-0.3
Reaction time trials on left0.10.20.6-0.5-0.50.5-0.4-0.30.30.50.30.3-0.30.4-0.00.4-0.4-0.2-0.2-0.2-0.6-0.70.70.7-0.8-0.2-0.4
Reaction time mean1.93.07.32.01.7-1.71.71.8-1.8-1.6-1.6-1.71.7-1.6-0.6-1.61.91.3-0.71.12.42.6-2.7-1.92.41.00.7
Reaction time mean AUC2.13.47.92.11.8-1.81.81.9-1.9-1.8-1.7-1.81.8-1.7-0.7-1.72.11.4-0.71.22.52.7-2.8-2.02.51.00.7
Median of all reaction times3.54.97.92.72.2-2.22.32.4-2.4-2.2-2.2-2.32.3-2.3-1.4-2.32.42.1-1.62.02.72.7-2.8-2.41.71.8-0.2
Reaction time omissions1.82.63.51.81.8-1.81.71.6-1.6-1.8-1.6-1.61.6-1.9-1.5-1.41.71.8-1.41.81.61.6-1.6-1.60.41.8-1.0
Reaction time false alarm rate0.10.10.5-0.10.3-0.30.10.1-0.1-0.3-0.1-0.10.1-0.20.2-0.20.20.00.2-0.00.40.5-0.6-0.50.7-0.10.3
Reaction time premature initiation rate2.63.55.52.12.3-2.32.22.2-2.2-2.3-2.1-2.22.2-1.9-1.7-2.12.11.6-1.51.52.12.0-1.8-0.81.20.20.6
Reaction time premature initiations1.22.13.21.61.8-1.81.71.8-1.8-1.7-1.7-1.81.8-1.4-1.6-1.71.61.3-1.41.21.51.4-1.2-0.30.70.10.3
Std. dev. reaction times0.61.17.00.80.7-0.70.60.7-0.7-0.6-0.5-0.60.6-0.50.5-0.30.90.20.50.01.51.8-2.0-1.02.70.01.4
Reaction time trials completed0.10.20.6-0.5-0.50.5-0.4-0.30.30.50.30.3-0.30.4-0.00.4-0.4-0.2-0.2-0.2-0.6-0.70.70.7-0.8-0.2-0.4
Reaction time trials AUC0.10.20.6-0.5-0.50.5-0.4-0.30.30.50.30.3-0.30.5-0.00.4-0.4-0.2-0.2-0.2-0.6-0.70.70.8-0.8-0.2-0.3
Run reversals in cocaine runway, females0.20.20.90.4-0.20.30.1-0.10.10.3-0.30.1-0.10.20.50.80.1-0.10.4-0.20.40.5-0.60.40.9-0.30.7
Run reversals in cocaine runway, males0.10.10.20.10.4-0.40.20.3-0.3-0.40.0-0.30.3-0.3-0.3-0.40.30.2-0.30.20.10.2-0.1-0.40.1-0.20.1
Latency to leave start box in cocaine runway0.50.61.1-0.7-0.80.7-0.8-0.80.80.90.80.7-0.70.90.80.5-0.7-0.91.0-0.9-0.6-0.50.50.50.3-1.00.8
Latency to leave start box in cocaine runway, F0.10.10.30.10.2-0.20.10.2-0.2-0.1-0.1-0.30.3-0.2-0.5-0.60.10.3-0.30.3-0.0-0.10.2-0.4-0.50.3-0.4
Latency to leave start box in cocaine runway, M2.12.02.7-1.3-1.51.5-1.5-1.61.61.61.51.6-1.61.51.41.4-1.5-1.51.5-1.5-1.3-1.21.21.2-0.1-1.20.7
Std. dev. time between licks in bursts0.30.40.70.50.7-0.70.60.6-0.6-0.7-0.6-0.60.6-0.8-0.6-0.60.70.7-0.60.70.70.8-0.8-0.80.30.8-0.4
Total sessions with >9 infusions0.40.53.7-0.4-0.20.2-0.3-0.30.30.20.50.3-0.30.1-0.70.2-0.40.1-0.80.2-0.9-1.11.30.5-1.90.2-1.2
Short access day 1 total inactive lever presses1.01.34.4-0.8-1.11.1-0.9-1.01.01.10.91.0-1.01.00.21.1-1.1-0.70.0-0.6-1.4-1.71.92.1-1.8-0.6-0.5
Short access day 10 total inactive lever presses0.30.71.7-0.9-0.80.8-0.9-0.80.80.81.00.8-0.80.90.91.0-0.9-1.01.0-1.0-0.7-0.60.61.30.3-0.90.8
Short access day 1 total infusions0.50.74.8-0.4-0.30.4-0.4-0.40.40.30.50.4-0.40.2-0.40.4-0.50.1-0.70.2-1.1-1.41.51.0-2.20.2-1.3
Short access day 10 total infusions0.40.53.90.0-0.10.1-0.1-0.10.10.10.30.1-0.10.0-0.70.2-0.20.3-0.90.4-0.8-1.01.20.7-2.00.3-1.3
Short access total infusions0.50.65.20.00.2-0.20.10.1-0.1-0.20.1-0.10.1-0.3-1.0-0.2-0.10.6-1.30.7-0.8-1.01.20.4-2.30.6-1.6
Short access day 1 locomotion0.91.13.60.71.1-1.00.91.1-1.1-1.1-0.8-1.01.0-1.0-1.9-1.00.91.3-1.81.30.30.10.1-0.6-1.60.7-1.3
Short access day 10 total locomotion0.61.11.80.81.2-1.21.11.2-1.2-1.3-1.0-1.21.2-1.0-1.3-1.31.20.9-0.90.81.11.1-1.0-1.00.50.20.1
Short access total locomotion0.30.31.70.20.5-0.30.30.4-0.4-0.5-0.2-0.40.4-0.4-1.3-0.20.30.6-1.00.7-0.1-0.30.4-0.1-1.20.4-1.0
One hour access (0.3 mA shock)0.50.61.8-0.9-0.60.7-0.8-0.70.70.61.00.6-0.60.70.30.4-0.7-0.4-0.0-0.3-1.1-1.21.30.4-1.3-0.5-0.5
Compulsive drug intake0.30.31.0-0.6-0.50.4-0.4-0.30.30.40.20.3-0.30.50.9-0.2-0.3-0.60.8-0.6-0.00.2-0.4-0.81.0-0.61.0
One hour access (shock baseline)0.40.74.4-0.6-0.30.3-0.5-0.40.40.30.80.4-0.40.3-0.30.3-0.6-0.1-0.70.1-1.2-1.41.70.9-2.1-0.1-1.2
Social response proportion2.83.25.52.11.8-1.81.91.7-1.7-1.8-1.9-1.71.7-1.9-1.2-1.72.01.9-1.21.72.22.2-2.3-2.01.21.7-0.4
Social responses0.60.81.2-1.1-1.01.0-1.0-1.11.11.01.01.0-1.00.91.11.1-0.9-0.91.0-0.9-0.7-0.60.50.70.0-0.30.2
Social time0.40.53.70.50.2-0.20.30.2-0.2-0.2-0.3-0.10.1-0.7-0.10.10.40.8-0.20.80.50.6-0.9-1.5-0.01.9-1.3
Soleus weight0.51.410.0-0.6-0.60.6-0.5-0.60.60.60.50.5-0.5-0.2-0.50.5-0.80.5-1.00.7-1.1-1.41.2-0.4-2.72.3-3.2
Bone: stiffness3.45.59.5-2.6-2.92.9-2.7-2.52.52.92.52.7-2.72.63.12.6-2.5-2.52.7-2.5-1.8-1.51.21.10.3-1.11.0
Tibialis anterior weight8.027.035.2-5.7-5.95.9-5.8-5.65.65.95.75.6-5.65.75.25.5-5.7-5.34.6-5.2-5.3-5.25.04.9-1.5-3.61.3
Time to tail flick, vehicle, before self-admin0.40.52.20.70.7-0.70.60.8-0.8-0.7-0.5-0.80.8-0.5-0.4-1.50.70.4-0.30.40.70.7-0.6-0.80.6-0.20.4
Time to tail flick, vehicle, after self-admin0.10.11.2-0.20.1-0.10.00.0-0.0-0.10.0-0.00.00.10.4-1.1-0.0-0.30.2-0.3-0.10.00.00.00.3-0.60.5
Time to tail flick, test, before self-admin0.50.50.7-0.7-0.80.8-0.7-0.80.80.80.70.8-0.80.80.60.9-0.7-0.80.7-0.8-0.7-0.60.60.8-0.0-0.60.4
Time to tail flick, test, after self-admin2.32.45.7-1.3-1.41.5-1.4-1.31.31.41.41.3-1.31.81.91.4-1.2-1.92.0-2.0-0.7-0.50.51.61.4-2.42.3
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.4-0.20.2-0.3-0.40.40.20.20.4-0.40.10.60.4-0.3-0.30.3-0.2-0.3-0.10.00.20.00.1-0.1
Delta time to tail flick, test, before/after SA0.20.21.30.20.2-0.20.20.3-0.3-0.2-0.2-0.30.30.10.3-0.40.3-0.20.4-0.30.50.6-0.50.11.0-0.81.1
Tibia length0.20.74.6-0.2-0.70.7-0.4-0.00.00.60.20.1-0.1-0.0-0.1-0.1-0.50.5-0.80.6-0.5-0.70.5-1.0-1.71.9-2.1
Ambulatory time before self-admin2.33.44.9-2.1-2.12.1-2.1-2.12.12.12.22.1-2.11.91.61.3-2.1-1.71.2-1.6-2.2-2.22.11.2-1.3-0.7-0.2
Ambulatory time after self-admin0.30.40.7-0.7-0.70.8-0.8-0.70.70.70.90.7-0.70.60.70.6-0.6-0.50.6-0.5-0.5-0.50.4-0.1-0.10.0-0.1
Bone: tissue strength0.20.21.5-0.4-0.40.4-0.3-0.20.20.40.30.4-0.40.10.50.2-0.1-0.00.4-0.10.10.2-0.5-1.20.30.6-0.1
Total heroin consumption1.21.34.40.50.9-1.00.91.0-1.0-0.9-0.9-1.01.0-1.2-1.8-0.80.71.4-2.01.50.1-0.20.3-0.4-1.81.7-2.1
Bone: trabecular number1.01.72.9-1.5-1.21.2-1.3-1.41.41.21.21.5-1.51.41.61.4-1.1-1.51.7-1.5-0.8-0.60.51.20.9-1.51.5
Bone: trabecular spacing0.10.10.40.40.2-0.20.20.2-0.2-0.1-0.2-0.20.2-0.10.1-0.10.20.00.1-0.10.40.4-0.40.10.6-0.20.5
Bone: trabecular thickness0.10.10.40.20.5-0.50.30.2-0.2-0.5-0.3-0.30.3-0.4-0.2-0.30.50.20.00.20.50.6-0.6-0.60.60.00.3
Bone: trabecular tissue density2.63.85.8-2.1-2.42.4-2.3-2.42.42.42.32.3-2.32.02.22.2-2.1-1.92.0-1.8-1.8-1.61.30.9-0.4-0.40.0
Water consumed over 24 hours0.70.91.9-1.0-1.01.0-0.9-0.90.91.00.80.9-0.91.21.00.8-0.9-1.20.9-1.2-0.8-0.70.81.40.3-1.41.1
Number of responses in last shaping day1.11.28.9-0.1-0.10.1-0.1-0.20.20.10.30.2-0.2-0.3-1.3-0.2-0.40.7-1.40.9-1.0-1.41.5-0.1-3.01.4-2.6