Hub : Genes

LOC120100575

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	gene expression	LOC120100575	0.13	0.08	1.6e-08	0.07	0.07	0.06	0.06	1.1e-08	1.5e-08	9.7e-08	8.3e-08
2	BLA	gene expression	LOC120100575	0.27	0.11	5.0e-13	0.16	0.18	0.17	0.18	1.1e-08	8.9e-10	1.4e-09	7.6e-10
3	PL	gene expression	LOC120100575	0.15	0.13	7.0e-11	0.1	0.08	0.09	0.09	1.2e-10	3.2e-09	5.1e-10	1.7e-10
4	Brain	gene expression	LOC120100575	0.06	0.04	1.1e-04	0.02	0.05	0.03	0.03	9.2e-03	3.4e-05	7.7e-04	5.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.0	0.0	0.0	-0.2	0.1	-0.1	0.0
Area under the delay curve	1.5	1.6	2.8	-1.1	1.1	-1.1	1.7
BMI with tail	5.6	18.0	19.2	-4.4	4.2	-4.2	4.1
BMI without tail	3.4	7.1	8.1	-2.8	2.7	-2.7	2.4
Body weight	4.8	20.0	23.0	-4.6	4.5	-4.8	3.9
Weight adjusted by age	0.1	0.1	0.4	-0.0	0.3	-0.6	-0.1
Bone surface	0.9	1.7	2.2	-1.4	1.5	-1.5	0.5
Bone volume	0.1	0.1	0.2	-0.4	0.4	-0.5	0.0
Breakpoint value in progressive ratio session	2.3	2.6	3.0	-1.7	1.7	-1.7	1.3
Number of licking bursts	2.4	2.8	3.4	-1.8	1.7	-1.8	1.2
Context. condit. distance diff. score	0.7	0.8	1.2	1.1	-1.0	1.0	-0.4
Locomotion velocity, session 1	0.3	0.4	0.4	-0.6	0.6	-0.7	-0.6
Locomotion distance, session 1	1.1	1.4	2.1	-1.3	1.5	-1.4	0.2
Locomotion velocity, session 2	0.3	0.4	0.5	-0.7	0.6	-0.7	-0.6
Locomotion distance, session 2	0.1	0.2	0.4	-0.2	0.4	-0.1	-0.6
Locomotion velocity, session 3	0.1	0.1	0.2	0.3	-0.2	0.4	-0.3
Locomotion distance, session 3	0.0	0.1	0.2	0.1	-0.2	0.1	-0.4
Stereotopy head waving bouts, day 3	0.1	0.1	0.5	-0.0	0.1	-0.1	-0.7
Stereotopy head waving duration, day 3	0.2	0.3	0.4	-0.5	0.6	-0.6	0.4
Locomotion velocity, session 7	0.1	0.1	0.2	-0.2	0.2	-0.3	-0.5
Locomotion distance, session 7	3.5	4.4	5.0	2.2	-2.1	2.2	-1.8
Stereotopy head waving bouts, day 7	1.2	1.4	2.1	-1.4	1.3	-1.4	0.1
Stereotopy head waving duration, day 7	1.2	1.5	2.3	-1.4	1.3	-1.5	0.1
Locomotion velocity, session 8	0.8	0.9	1.3	-1.1	0.9	-1.1	0.7
Locomotion distance, session 8	0.0	0.0	0.1	-0.1	0.2	-0.1	-0.0
Degree of sensitization distance	3.7	3.7	4.3	2.1	-2.0	2.0	-1.5
Degree of sensitization stereotypy	1.5	1.6	2.3	-1.5	1.3	-1.5	0.5
Conditioned locomotion	2.9	3.4	4.2	2.0	-1.9	1.9	-1.4
Cocaine response after cond. corrected	0.3	0.3	0.5	0.7	-0.6	0.6	0.2
Cocaine response after cond. not corrected	0.2	0.2	0.3	0.6	-0.5	0.5	-0.1
Cocaine response before conditioning	0.5	0.6	0.9	-1.0	0.8	-0.9	0.1
Saline control response	0.4	0.5	0.9	-0.7	1.0	-0.7	0.5
Bone: connectivity density	1.4	2.1	2.8	-1.7	1.7	-1.6	0.7
Bone: cortical apparent density	1.8	2.4	2.9	1.4	-1.3	1.7	-1.7
Bone: cortical area	0.6	0.9	1.4	-0.9	1.2	-0.9	0.8
Bone: cortical porosity	3.4	3.7	5.3	-1.9	1.6	-1.9	2.3
Bone: cortical porosity	2.1	2.3	2.9	-1.5	1.3	-1.5	1.7
Bone: cortical thickness	0.1	0.2	0.5	-0.2	0.4	-0.1	0.7
Bone: cortical thickness	0.3	0.4	0.7	-0.7	0.8	-0.6	0.4
Bone: cortical tissue density	1.9	2.5	3.1	1.5	-1.4	1.7	-1.8
Condit. Reinf. active minus inactive responses	0.4	0.5	0.8	-0.5	0.8	-0.6	0.9
Condit. Reinf. active-inactive response ratio	0.8	0.8	1.8	-0.6	0.8	-0.7	1.3
Condit. Reinf. active responses	2.1	2.5	3.6	-1.4	1.9	-1.4	1.6
Condit. Reinf. inactive responses	2.4	2.9	4.4	-1.8	2.1	-1.7	1.0
Incentive salience index mean	0.6	0.7	0.9	-0.7	0.9	-0.6	0.9
Condit. Reinf. lever presses	0.4	0.5	1.0	-0.8	1.0	-0.6	0.4
Condit. Reinf. active minus inactive responses	0.5	0.7	0.7	-0.8	0.8	-0.8	0.8
Condit. Reinf. active-inactive response ratio	0.1	0.2	0.2	0.4	-0.4	0.4	0.4
Condit. Reinf. active responses	1.4	2.0	2.6	-1.6	1.6	-1.4	0.8
Condit. Reinf. inactive responses	4.3	5.3	7.2	-2.7	2.7	-2.3	1.3
Condit. Reinf. lever presses	1.4	1.8	2.5	-1.3	1.3	-1.1	1.6
Condit. Reinf. lever reinforcers received	1.2	1.8	2.4	-1.5	1.5	-1.3	0.8
Conditioned reinforcement - actives	5.3	5.3	5.5	2.3	-2.2	2.3	-2.4
Conditioned reinforcement - inactives	0.9	1.0	1.4	1.2	-1.0	1.2	-0.6
Conditioned locomotion	0.5	0.5	1.2	0.5	-0.5	0.7	-1.1
Patch foraging indifference point 0 sec	1.4	2.3	2.7	-1.3	1.4	-1.6	1.6
Patch foraging indifference point AUC	1.1	1.2	2.3	-1.5	1.2	-1.1	0.1
Delay disc. indifference point, 0s delay	1.0	1.1	2.3	0.8	-0.9	0.9	-1.5
Delay disc. indifference point, 16s delay	2.2	2.2	3.6	-1.3	1.4	-1.3	1.9
Delay disc. indifference point, 2s delay	0.3	0.3	0.4	-0.6	0.4	-0.5	0.7
Delay disc. indifference point, 24s delay	0.1	0.1	0.3	0.0	0.1	-0.1	0.6
Delay disc. indifference point, 4s delay	1.9	2.0	2.1	-1.4	1.3	-1.4	1.4
Delay disc. indifference point, 8s delay	0.1	0.1	0.4	0.1	-0.1	-0.0	0.6
Indifference point function ln k	0.5	0.7	0.8	0.9	-0.9	0.9	0.5
Indifference point function log k	0.5	0.7	0.8	0.9	-0.9	0.9	0.5
Patch foraging total patch changes 0 sec	1.4	2.3	2.6	-1.3	1.5	-1.6	1.6
Patch foraging total patch changes 12 sec	0.0	0.0	0.0	-0.0	0.1	-0.0	-0.2
Patch foraging total patch changes 18 sec	1.1	1.4	1.8	-1.2	1.2	-1.3	1.0
Patch foraging total patch changes 24 sec	3.2	3.9	4.6	-2.1	2.1	-2.1	1.4
Patch foraging total patch changes 6 sec	1.9	2.8	3.5	-1.8	1.7	-1.9	1.4
Patch foraging time to switch 0 sec	2.0	3.1	4.1	2.0	-1.8	1.9	-1.3
Patch foraging water rate 0 sec	0.3	0.5	0.8	-0.9	0.7	-0.8	0.5
Patch foraging water rate 12 sec	0.2	0.4	0.6	-0.7	0.6	-0.8	-0.0
Patch foraging water rate 18 sec	0.3	0.4	0.6	-0.6	0.7	-0.7	0.1
Patch foraging water rate 24 sec	0.3	0.4	0.5	-0.6	0.7	-0.7	-0.3
Patch foraging water rate 6 sec	0.0	0.1	0.2	-0.0	-0.0	0.1	-0.5
Seeking ratio, delayed vs. immediate footshock	3.4	3.9	5.3	-1.9	2.0	-1.7	2.3
Distance traveled before self-admin	1.4	1.5	2.0	-1.3	1.4	-1.3	0.8
Distance traveled after self-admin	3.3	3.7	4.5	-2.1	2.0	-2.1	1.4
Extensor digitorum longus weight	4.8	18.9	19.8	-4.3	4.3	-4.4	4.4
Bone: elastic displacement	0.7	0.8	1.0	1.0	-0.9	0.9	0.6
Bone: elastic work	1.2	1.5	2.3	1.5	-1.4	1.4	-0.2
Bone: endosteal estimation	1.1	2.4	3.2	-1.7	1.7	-1.8	0.8
Bone: endosteal perimeter	0.3	0.6	1.0	-0.9	1.0	-0.8	0.1
Epididymis fat weight	2.7	6.4	7.6	-2.8	2.7	-2.6	1.9
Delta time in closed arm before/after self-admin	1.1	1.0	1.3	-1.1	1.0	-1.1	0.8
Delta time in open arm before/after self-admin	0.4	0.4	0.6	0.6	-0.8	0.5	-0.7
Diff in mean of infusions in LGA sessions	0.6	0.6	1.0	-0.7	0.8	-0.7	1.0
Delay discount exponential model param	1.5	1.6	3.0	1.0	-1.0	1.1	-1.7
Extinction: sum of active levers before priming	0.1	0.1	0.1	-0.4	0.4	-0.3	0.1
Active lever presses in extinction session 6	0.0	0.0	0.1	0.1	-0.2	0.0	0.4
Bone: final force	3.2	5.2	6.1	-2.3	2.5	-2.3	1.9
Bone: final moment	3.1	5.0	5.7	-2.3	2.4	-2.3	2.0
Food consumed during 24 hour testing period	0.1	0.1	0.3	-0.1	0.1	0.1	0.5
Glucose	0.6	0.9	1.3	1.1	-0.9	1.0	-0.7
Heart weight	0.9	1.3	2.9	-0.8	1.1	-0.8	1.7
Delay discount hyperbolic model param	1.3	1.3	2.5	1.0	-0.9	1.0	-1.6
Intermittent access intake day 1-15 change	2.5	2.5	3.1	1.5	-1.5	1.5	-1.8
Intermittent access intake escalation	2.7	2.7	3.0	1.7	-1.7	1.6	-1.5
Intermittent access intake escalation 2	1.0	1.0	1.2	1.1	-1.0	0.9	-1.1
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.2	-0.2	0.4	-0.2	0.5
Intermitt. access day 15 inactive lever presses	0.3	0.3	0.6	-0.4	0.5	-0.4	0.8
Intermitt. access escalation Index	0.5	0.5	0.7	0.7	-0.8	0.8	-0.2
Intermittent access day 1 total infusions	1.4	1.6	2.5	1.0	-1.1	1.3	-1.6
Intermittent access day 15 total infusions	3.9	4.3	4.8	2.0	-2.0	2.1	-2.2
Intermittent access terminal intake (last 3 days)	3.7	4.0	5.5	1.8	-1.8	2.0	-2.3
Intermittent access total infusions	1.7	1.8	3.1	1.2	-1.1	1.3	-1.8
Intermittent access day 1 locomotion	0.1	0.1	0.3	0.3	-0.2	0.4	-0.5
Intermittent access day 15 total locomotion	1.4	1.5	2.0	1.4	-1.2	1.3	-1.0
Intermittent access total locomotion	0.2	0.2	0.5	0.5	-0.2	0.4	-0.7
Intermittent access standard deviation	0.1	0.1	0.3	0.5	-0.3	0.3	-0.3
Left kidney weight	0.1	0.4	0.6	-0.7	0.6	-0.8	0.3
Right kidney weight	0.3	1.0	1.4	-1.0	0.9	-1.2	0.8
Cocaine induced anxiety	1.4	1.7	1.8	-1.2	1.4	-1.3	1.3
Post-drug Anxiety	1.7	1.9	2.1	-1.4	1.4	-1.3	1.4
Baseline Anxiety	0.2	0.2	0.3	0.4	-0.5	0.5	-0.2
Tail length	0.2	0.5	0.6	-0.8	0.8	-0.8	0.4
Length with tail	0.8	2.9	4.1	-1.7	1.7	-2.0	1.3
Length without tail	1.3	2.9	3.6	-1.6	1.7	-1.9	1.6
Times rat made contact with spout	0.5	0.6	1.1	1.0	-0.6	1.1	-0.3
Lifetime Intake	1.4	1.6	2.7	1.1	-1.0	1.2	-1.6
Liver weight, left	0.0	0.0	0.0	0.1	-0.2	0.1	-0.1
Liver weight, right	0.1	0.2	0.3	0.5	-0.5	0.5	-0.4
Locomotor activity	0.5	0.7	1.6	-0.8	0.6	-0.5	1.3
Locomotor testing distance	3.8	6.4	7.8	-2.7	2.4	-2.2	2.8
Locomotor testing rearing	0.5	0.7	1.3	-0.9	0.7	-0.5	1.1
Locomotion in novel chamber	0.9	1.1	1.7	-0.9	0.9	-1.3	1.0
Locomotion in novel chamber post-restriction	1.0	1.1	1.6	-1.1	1.1	-1.3	0.8
Fecal boli incidents, locomotor time 1	0.9	1.0	1.4	1.2	-1.0	1.1	-0.5
Change in fecal boli incidents, locomotor task	1.2	1.1	1.5	-1.1	1.2	-1.2	0.6
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.5	0.3	-0.3	0.3	-0.7
Bouts of movement, locomotor time 1	0.8	0.9	1.3	1.1	-1.1	0.9	-0.6
Total resting periods, locomotor time 1	1.7	1.8	2.6	1.6	-1.5	1.4	-0.7
Rest time, locomotor task time 1	2.1	2.4	3.1	1.8	-1.6	1.7	-0.8
Distance moved, locomotor task time 1	1.8	2.0	2.9	-1.7	1.5	-1.6	0.5
Vertical activity count, locomotor time 1	1.7	1.8	2.6	-1.6	1.4	-1.5	0.6
Time >=10cm from walls, locomotor time 2	1.0	1.1	1.2	0.9	-1.0	1.0	-1.1
Bouts of movement, locomotor time 2	2.4	2.5	3.2	1.8	-1.6	1.8	-1.1
Total resting periods, locomotor time 2	1.2	1.3	1.8	1.3	-1.2	1.3	-0.6
Rest time, locomotor task time 2	0.2	0.2	0.4	0.6	-0.4	0.5	0.2
Distance moved, locomotor task time 2	1.0	1.1	1.7	-1.3	1.1	-1.3	0.1
Vertical activity count, locomotor time 2	0.4	0.5	0.6	-0.8	0.7	-0.8	-0.3
Light reinforcement 1	0.4	0.8	1.2	0.9	-0.9	1.1	-0.5
Light reinforcement 2	0.2	0.2	0.4	0.5	-0.6	0.5	-0.3
Bone: marrow area	1.2	2.5	3.4	-1.7	1.8	-1.8	0.9
Bone: maximum diameter	0.3	0.6	1.0	-0.7	1.0	-0.9	0.2
Bone: maximum force	1.2	2.1	2.5	-1.5	1.6	-1.4	1.4
Bone: maximum moment	1.2	2.1	2.3	-1.4	1.5	-1.4	1.5
Mean time between licks in bursts	0.1	0.1	0.2	0.1	-0.4	0.2	-0.3
Mean num. licks in bursts	2.8	3.3	4.6	2.1	-1.8	2.1	-0.9
Cd content in liver	1.8	1.9	2.1	1.4	-1.4	1.3	-1.4
Co content in liver	0.3	0.3	0.7	-0.3	0.6	-0.4	0.8
Cu content in liver	0.6	0.7	0.9	-0.8	0.6	-0.9	0.9
Fe content in liver	0.3	0.4	1.3	-0.3	0.3	-0.3	1.1
K content in liver	0.1	0.1	0.2	0.2	-0.5	0.0	-0.3
Mg content in liver	0.5	0.5	0.7	0.8	-0.9	0.7	-0.5
Mn content in liver	1.5	1.7	2.2	1.3	-1.5	1.3	-1.1
Na content in liver	1.3	1.4	2.0	-1.2	1.4	-1.3	0.6
Rb content in liver	1.2	1.5	2.0	-1.2	1.1	-1.2	1.4
Se content in liver	1.1	1.3	3.2	0.9	-1.0	0.7	-1.8
Sr content in liver	0.2	0.2	0.3	-0.3	0.4	-0.6	-0.3
Zn content in liver	0.5	0.5	0.9	0.9	-0.8	0.7	0.0
Bone: minimum diameter	1.0	1.8	2.4	-1.3	1.6	-1.3	1.2
Time in familiar zone, hab. session 1	0.2	0.2	0.3	0.5	-0.4	0.4	-0.4
Time in novel zone, hab. session 1	0.1	0.1	0.2	-0.4	0.4	-0.3	-0.0
Total zone transitions, hab. session 1	2.2	3.0	4.2	-1.6	1.8	-1.4	2.1
Total locomotion distance, hab. session 1	1.4	2.0	2.5	-1.4	1.6	-1.3	1.4
Locomotion velocity, hab. session 1	1.9	2.7	3.1	-1.6	1.7	-1.6	1.7
Time in familiar zone, hab. session 2	2.1	2.1	2.3	1.3	-1.5	1.5	-1.5
Time in novel zone, hab. session 2	1.9	1.9	2.2	-1.3	1.4	-1.5	1.4
Total zone transitions, hab. session 2	2.3	3.0	4.1	-1.7	2.0	-1.8	1.3
Total locomotion distance, hab. session 2	1.0	1.4	2.1	-1.0	1.4	-1.2	0.9
Locomotion velocity, hab. session 2	1.3	1.8	2.8	-1.3	1.7	-1.4	0.9
Novel to familiar place preference ratio	0.3	0.3	0.7	-0.5	0.2	-0.4	0.8
Novelty place preference	0.4	0.4	0.9	-0.5	0.3	-0.4	1.0
Time in novel zone, NPP test	0.7	0.7	1.6	-0.8	0.6	-0.7	1.2
Total zone transitions, NPP test	0.4	0.5	0.9	-0.8	1.0	-0.7	-0.2
Total locomotion distance, NPP test	0.2	0.3	0.6	-0.5	0.8	-0.5	-0.2
Locomotion velocity, NPP test	0.1	0.2	0.3	-0.3	0.6	-0.4	-0.4
Intraocular pressure	0.8	1.1	1.4	1.1	-1.2	1.1	-0.8
Delta distance traveled before/after self-admin	0.2	0.2	0.4	-0.6	0.3	-0.6	0.3
Delta ambulatory time before/after self-admin	0.2	0.2	0.4	-0.6	0.3	-0.6	0.3
Parametrial fat weight	0.3	0.6	0.8	-0.7	0.8	-0.9	0.6
Pavlov. Cond. lever latency	0.2	0.3	0.4	0.7	-0.6	0.5	-0.0
Pavlov. Cond. magazine entry latency	1.6	2.0	2.6	-1.6	1.4	-1.6	1.0
Pavlov. Cond. change in total contacts	0.1	0.1	0.2	-0.4	0.5	-0.4	0.1
Pavlov. Cond. index score	1.4	1.8	2.5	-1.6	1.5	-1.5	0.5
Pavlov. Cond. latency score	0.9	1.2	1.7	-1.3	1.2	-1.2	0.3
Pavlov. Cond. lever contacts	0.5	0.6	1.0	-1.0	0.8	-0.9	-0.1
Pavlov. Cond. magazine entry number	2.1	2.6	3.4	1.8	-1.7	1.8	-1.0
Pavlov. Cond. intertrial magazine entries	1.1	1.3	1.9	1.4	-1.2	1.3	-0.5
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.0	2.8	-1.7	1.5	-1.6	0.6
Pavlov. Cond. response bias	1.6	2.0	2.7	-1.6	1.5	-1.6	0.7
Pavlov. Cond. lever latency	3.9	5.2	6.4	2.5	-2.4	2.4	-1.8
Pavlov. Cond. magazine entry latency	1.2	1.3	2.7	-1.0	1.0	-0.9	1.6
Pavlov. Cond. change in total contacts	5.8	8.1	9.4	-3.1	2.9	-2.9	2.4
Pavlov. Cond. index score	5.1	6.5	7.0	-2.6	2.6	-2.5	2.5
Pavlov. Cond. latency score	3.9	4.8	5.1	-2.3	2.2	-2.1	2.2
Pavlov. Cond. lever contacts	4.2	5.7	7.2	-2.7	2.5	-2.5	1.7
Pavlov. Cond. magazine entry number	4.4	5.4	6.5	2.3	-2.3	2.1	-2.5
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	0.3	-0.3	0.4	-0.5
Pavlov. Cond. lever-magazine prob. diff.	4.9	6.2	7.0	-2.6	2.6	-2.4	2.3
Pavlov. Cond. response bias	5.4	7.3	8.5	-2.9	2.8	-2.8	2.4
Time in closed arm before self-admin	0.9	1.0	1.3	0.9	-1.0	0.9	-1.1
Time in closed arm after self-admin	0.2	0.2	0.4	0.3	-0.3	0.2	-0.6
Time in open arm before self-admin	5.0	5.4	5.8	-2.4	2.4	-2.2	2.3
Time in open arm after self-admin	0.3	0.4	0.5	-0.7	0.5	-0.5	0.7
Bone: periosteal estimation	1.0	2.1	2.8	-1.5	1.7	-1.6	0.9
Bone: periosteal perimeter	0.2	0.4	0.8	-0.6	0.9	-0.6	0.1
Bone: post-yield work	0.2	0.2	0.4	-0.6	0.4	-0.4	0.4
Progressive ratio test 1 active lever presses	0.1	0.1	0.2	-0.3	0.3	-0.2	-0.5
Progressive ratio test 1 breakpoint	0.1	0.1	0.3	-0.3	0.3	-0.1	-0.5
Progressive ratio test 1 inactive lever presses	0.3	0.3	0.8	0.5	-0.4	0.4	-0.9
Progressive ratio test 2 active lever presses	3.6	3.8	6.1	1.7	-1.8	1.8	-2.5
Progressive ratio test 2 breakpoint	2.2	2.5	4.9	1.3	-1.3	1.3	-2.2
Progressive ratio test 2 inactive lever presses	1.3	1.4	1.6	1.2	-1.1	1.3	-1.3
Incentive Sensitization - Responses	2.7	2.8	4.4	1.4	-1.5	1.5	-2.1
Incentive Sensitization - Breakpoint	2.6	2.6	4.3	1.4	-1.5	1.4	-2.1
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.1	-0.3	0.3	-0.4	-0.1
Progressive ratio	0.3	0.3	0.5	0.6	-0.5	0.7	-0.3
Food seeking constrained by brief footshock	0.4	0.5	1.4	-0.3	0.7	-0.2	1.2
Seeking ratio, punishment vs. effort	0.7	0.9	1.0	-1.0	1.0	-0.9	1.0
Retroperitoneal fat weight	1.1	3.6	4.7	-2.1	2.1	-2.2	1.1
Reaction time number correct	0.7	1.1	3.2	0.6	-0.6	0.6	-1.8
Reaction time mean minus median	4.3	5.7	10.2	-2.0	2.0	-2.2	3.2
Reaction time mean minus median AUC	2.3	2.9	5.3	-1.5	1.5	-1.4	2.3
Reaction time num false alarms	0.0	0.0	0.0	0.1	-0.1	0.2	0.1
Reaction time num false alarms AUC	0.0	0.1	0.1	0.1	-0.2	0.3	-0.3
Reaction time trials correct on left	0.7	1.1	3.2	0.6	-0.6	0.6	-1.8
Reaction time trials on left	0.7	1.0	2.9	0.6	-0.6	0.6	-1.7
Reaction time mean	2.2	3.1	7.2	-1.2	1.4	-1.4	2.7
Reaction time mean AUC	2.2	2.9	7.2	-1.1	1.3	-1.3	2.7
Median of all reaction times	1.0	1.4	4.1	-0.7	0.8	-0.7	2.0
Reaction time omissions	2.2	3.0	8.4	-1.0	0.9	-1.3	2.9
Reaction time false alarm rate	0.1	0.2	0.5	-0.4	0.3	-0.3	0.7
Reaction time premature initiation rate	1.7	2.3	2.8	1.5	-1.7	1.7	-1.2
Reaction time premature initiations	2.0	2.8	3.5	1.5	-1.7	1.6	-1.9
Std. dev. reaction times	4.3	6.1	10.5	-2.1	2.1	-2.2	3.2
Reaction time trials completed	0.7	1.0	2.9	0.6	-0.6	0.6	-1.7
Reaction time trials AUC	0.7	0.9	2.7	0.6	-0.6	0.6	-1.7
Run reversals in cocaine runway, females	0.7	0.7	1.0	-0.8	1.0	-0.9	0.2
Run reversals in cocaine runway, males	0.9	0.9	1.2	-1.1	1.0	-0.9	0.8
Latency to leave start box in cocaine runway	0.3	0.4	1.1	-0.0	-0.3	0.5	1.1
Latency to leave start box in cocaine runway, F	0.6	0.7	1.5	0.5	-0.9	1.2	0.1
Latency to leave start box in cocaine runway, M	0.3	0.3	1.0	-0.1	0.0	-0.2	1.0
Std. dev. time between licks in bursts	0.5	0.6	1.2	-0.6	0.8	-0.6	1.1
Total sessions with >9 infusions	0.3	0.3	0.7	0.6	-0.5	0.8	0.0
Short access day 1 total inactive lever presses	0.3	0.4	0.6	0.5	-0.4	0.7	-0.8
Short access day 10 total inactive lever presses	0.5	0.6	0.9	-0.6	0.8	-0.7	0.9
Short access day 1 total infusions	0.2	0.2	0.4	0.6	-0.3	0.5	-0.3
Short access day 10 total infusions	0.0	0.1	0.1	-0.3	0.3	-0.0	-0.2
Short access total infusions	0.4	0.4	0.8	0.6	-0.4	0.7	-0.9
Short access day 1 locomotion	0.1	0.1	0.2	0.1	0.3	-0.0	0.4
Short access day 10 total locomotion	0.3	0.3	0.4	-0.4	0.6	-0.6	0.6
Short access total locomotion	0.0	0.1	0.1	0.3	-0.0	0.3	-0.2
One hour access (0.3 mA shock)	2.2	2.6	5.6	1.4	-1.2	1.2	-2.4
Compulsive drug intake	0.5	0.5	0.7	-0.6	0.8	-0.9	0.4
One hour access (shock baseline)	4.3	5.0	6.1	2.1	-2.1	2.2	-2.5
Social response proportion	7.7	8.3	10.3	3.2	-3.0	3.0	-2.2
Social responses	0.8	1.0	1.4	1.1	-0.8	0.9	-1.2
Social time	3.5	4.6	5.9	2.4	-2.4	2.3	-1.3
Soleus weight	1.0	2.9	3.2	-1.8	1.6	-1.6	1.8
Bone: stiffness	1.3	2.1	2.6	-1.6	1.6	-1.4	1.1
Tibialis anterior weight	7.0	23.9	27.6	-5.2	5.1	-5.2	3.9
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.3	0.5	-0.4	0.5	0.5
Time to tail flick, vehicle, after self-admin	2.2	2.3	3.7	1.4	-1.5	1.2	-1.9
Time to tail flick, test, before self-admin	0.2	0.2	0.7	-0.2	0.2	-0.2	0.8
Time to tail flick, test, after self-admin	0.1	0.1	0.4	-0.1	0.1	-0.1	0.7
Delta time to tail flick, vehicle, before/after SA	4.0	3.9	6.2	1.7	-1.9	1.6	-2.5
Delta time to tail flick, test, before/after SA	0.0	0.0	0.0	-0.1	0.0	-0.0	-0.1
Tibia length	1.1	3.2	7.8	1.3	-1.4	1.1	-2.8
Ambulatory time before self-admin	0.4	0.4	0.7	-0.7	0.8	-0.6	0.1
Ambulatory time after self-admin	1.5	1.7	2.5	-1.6	1.4	-1.4	0.6
Bone: tissue strength	0.3	0.3	1.2	-0.1	-0.0	-0.1	1.1
Total heroin consumption	0.7	0.9	1.0	-0.9	1.0	-0.9	1.0
Bone: trabecular number	0.2	0.3	0.6	-0.7	0.5	-0.6	-0.0
Bone: trabecular spacing	0.7	0.9	1.1	1.0	-0.9	1.0	-0.9
Bone: trabecular thickness	0.6	0.7	0.8	0.8	-0.9	0.8	-0.8
Bone: trabecular tissue density	2.4	3.4	4.4	2.0	-2.1	2.1	-1.0
Water consumed over 24 hours	0.1	0.1	0.3	-0.1	0.3	-0.1	0.6
Number of responses in last shaping day	0.1	0.1	0.1	-0.1	0.3	-0.3	0.1