Hub : Genes

Fam219a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Fam219a 0.56 0.16 0.0e+00 0.36 0.38 0.4 0.4 1.0e-19 3.1e-21 1.0e-22 1.9e-22
2 Brain mRNA stability Fam219a 0.04 0.03 4.7e-04 0.04 0.03 0.04 0.04 6.0e-05 1.0e-03 3.0e-04 1.2e-04
3 BLA alternative TSS NM_001415979.1 0.07 0.05 1.4e-03 0.03 0.03 0.01 0.03 8.7e-03 1.1e-02 9.0e-02 7.6e-03
4 Liver gene expression Fam219a 0.04 0.04 1.4e-03 0.02 0.01 0.01 0.01 6.3e-03 1.4e-02 7.2e-03 3.9e-02
5 pVTA gene expression Fam219a 0.1 0.06 2.3e-08 0.12 0.09 0.09 0.1 7.2e-10 1.1e-07 9.2e-08 1.4e-08
6 BLA isoform ratio NM_001415979.1 0.06 0.05 3.4e-03 0.03 0.02 0.01 0.02 7.0e-03 4.2e-02 5.6e-02 3.3e-02
7 Brain gene expression Fam219a 0.2 0.1 0.0e+00 0.15 0.1 0.16 0.12 3.6e-14 6.6e-10 3.9e-15 2.2e-11
8 BLA alternative TSS XM_006238103.5 0.08 0.05 8.8e-04 0.03 0.03 0.04 0.04 6.3e-03 6.7e-03 5.0e-03 5.3e-03
9 NAcc gene expression Fam219a 0.1 0.06 3.9e-16 0.1 0.09 0.11 0.1 9.8e-15 1.7e-13 1.4e-16 2.3e-15
10 PL alternative TSS NM_001415979.1 0.04 0.05 2.4e-03 0.03 0.02 0.01 0.02 6.8e-04 1.1e-03 8.0e-03 1.2e-03
11 BLA alternative TSS NM_001415979.1 0.06 0.05 3.0e-03 0.03 0.02 0.01 0.03 1.4e-02 2.0e-02 1.2e-01 1.4e-02
12 BLA alternative TSS XM_006238103.5 0.07 0.05 1.4e-03 0.03 0.03 0.01 0.03 9.9e-03 1.4e-02 1.0e-01 1.2e-02
13 Adipose mRNA stability Fam219a 0.03 0.02 1.7e-03 0.02 0.02 0.02 0.02 8.9e-04 1.5e-03 2.4e-03 2.2e-03
14 PL alternative TSS XM_006238103.5 0.04 0.03 6.4e-04 0.03 0.03 0.03 0.03 1.4e-04 3.5e-04 2.8e-04 2.4e-04
15 PL alternative TSS NM_001415979.1 0.04 0.04 1.3e-03 0.03 0.03 0.02 0.03 3.2e-04 5.1e-04 2.5e-03 7.6e-04
16 PL alternative TSS XM_006238103.5 0.03 0.03 5.8e-03 0.02 0.02 0.01 0.02 1.5e-03 2.4e-03 1.2e-02 2.7e-03
17 PL gene expression Fam219a 0.41 0.16 0.0e+00 0.16 0.16 0.17 0.18 1.5e-17 3.7e-17 1.4e-18 8.7e-19
18 IC gene expression Fam219a 0.68 0.15 3.5e-09 0.21 0.18 0.15 0.17 4.6e-09 3.7e-08 6.6e-07 9.9e-08
19 RMTg gene expression Fam219a 0.23 0.15 4.0e-04 0.07 0.08 0.11 0.07 7.8e-03 4.8e-03 6.1e-04 5.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.12.12.9-1.51.1-1.3-1.0-1.01.3-1.5-1.4-1.41.71.4-1.41.5-1.71.7-1.71.5-1.51.6
Area under the delay curve0.71.11.81.2-0.91.00.80.8-1.00.81.00.5-1.0-1.11.1-1.31.2-1.21.2-1.21.1-1.2
BMI with tail1.44.96.1-2.52.0-2.4-1.9-1.92.4-2.4-2.3-2.02.42.2-2.22.1-2.22.2-2.22.3-2.22.0
BMI without tail1.05.47.2-2.42.2-2.3-2.2-2.22.3-2.7-2.4-2.42.52.3-2.32.4-2.42.4-2.42.4-2.12.1
Body weight2.611.215.6-3.53.8-3.6-3.7-3.73.6-4.0-3.6-3.53.13.2-3.23.3-3.13.1-3.13.1-3.02.2
Weight adjusted by age0.00.10.4-0.10.6-0.5-0.6-0.60.5-0.3-0.3-0.1-0.2-0.00.0-0.10.3-0.20.20.00.0-0.2
Bone surface0.61.21.6-1.11.1-1.0-1.1-1.11.0-1.2-1.1-1.21.11.0-1.01.1-1.11.1-1.11.0-1.00.7
Bone volume0.51.11.4-1.10.9-0.9-0.9-0.90.9-1.1-1.0-1.21.21.0-1.01.0-1.11.1-1.11.1-1.10.9
Breakpoint value in progressive ratio session1.32.45.91.3-0.50.20.80.8-0.10.81.10.2-1.9-1.81.8-2.32.2-2.22.2-1.71.7-2.4
Number of licking bursts2.57.78.9-2.92.7-2.7-2.8-2.82.6-2.7-2.9-3.02.82.8-2.82.8-2.82.8-2.82.8-2.82.4
Context. condit. distance diff. score0.10.10.30.4-0.50.50.40.4-0.50.30.40.2-0.3-0.30.3-0.30.1-0.10.1-0.30.3-0.2
Locomotion velocity, session 10.50.62.70.10.9-0.9-0.9-0.90.9-0.6-0.1-0.1-0.5-0.70.7-0.50.4-0.40.4-0.80.8-1.6
Locomotion distance, session 10.10.20.7-0.10.6-0.6-0.6-0.60.6-0.6-0.2-0.2-0.1-0.30.3-0.20.1-0.10.1-0.40.4-0.8
Locomotion velocity, session 21.92.33.3-1.61.4-1.4-1.3-1.31.4-1.7-1.6-1.31.81.6-1.61.6-1.61.6-1.61.5-1.41.5
Locomotion distance, session 21.52.13.4-1.51.8-1.7-1.8-1.81.7-1.8-1.6-1.51.41.2-1.21.2-1.31.3-1.31.1-1.00.5
Locomotion velocity, session 30.10.10.5-0.10.5-0.5-0.4-0.40.5-0.3-0.2-0.1-0.4-0.10.1-0.20.1-0.10.1-0.30.3-0.7
Locomotion distance, session 31.31.52.6-1.31.6-1.5-1.5-1.51.5-1.6-1.3-1.30.91.0-1.01.0-1.01.0-1.00.9-1.00.5
Stereotopy head waving bouts, day 30.20.20.8-0.20.5-0.5-0.5-0.50.50.3-0.2-0.1-0.9-0.10.1-0.30.6-0.60.60.00.0-0.7
Stereotopy head waving duration, day 30.10.10.7-0.20.2-0.3-0.2-0.20.30.6-0.10.0-0.8-0.00.0-0.20.5-0.50.50.1-0.1-0.5
Locomotion velocity, session 70.10.10.10.1-0.20.10.30.3-0.10.30.20.3-0.3-0.20.2-0.20.3-0.30.3-0.20.2-0.2
Locomotion distance, session 70.10.10.3-0.40.5-0.6-0.4-0.40.6-0.5-0.4-0.50.30.2-0.20.1-0.20.2-0.20.3-0.20.0
Stereotopy head waving bouts, day 71.51.72.6-1.41.5-1.5-1.6-1.61.5-1.2-1.5-1.10.61.2-1.21.4-1.11.1-1.11.3-1.30.7
Stereotopy head waving duration, day 71.01.21.7-1.21.2-1.2-1.3-1.31.2-0.9-1.2-0.90.51.1-1.11.2-0.90.9-0.91.2-1.20.7
Locomotion velocity, session 80.10.10.70.10.3-0.3-0.4-0.40.3-0.10.00.1-0.3-0.40.4-0.20.1-0.10.1-0.50.5-0.8
Locomotion distance, session 80.10.10.3-0.20.5-0.4-0.6-0.60.4-0.5-0.2-0.30.0-0.00.00.0-0.20.2-0.2-0.10.1-0.5
Degree of sensitization distance0.70.71.20.8-1.00.91.01.0-0.91.10.90.8-0.7-0.80.8-0.90.9-0.90.9-0.60.7-0.5
Degree of sensitization stereotypy1.51.72.2-1.41.3-1.3-1.4-1.41.3-1.3-1.4-1.11.01.3-1.31.5-1.31.3-1.31.3-1.31.0
Conditioned locomotion0.10.10.50.20.2-0.2-0.3-0.30.20.00.00.1-0.4-0.30.3-0.20.4-0.40.4-0.40.4-0.7
Cocaine response after cond. corrected1.42.13.41.4-0.80.81.01.0-0.81.41.31.2-1.7-1.71.7-1.81.8-1.71.7-1.51.4-1.8
Cocaine response after cond. not corrected1.21.83.41.2-0.60.60.80.8-0.61.21.21.1-1.6-1.51.5-1.71.7-1.71.7-1.41.4-1.9
Cocaine response before conditioning0.91.11.3-1.11.0-1.0-0.9-0.91.0-1.0-1.1-1.01.11.1-1.11.1-1.11.1-1.11.0-0.90.9
Saline control response1.11.53.0-1.51.7-1.7-1.6-1.61.7-1.2-1.4-1.00.61.0-1.01.1-0.80.8-0.81.0-0.90.1
Bone: connectivity density0.50.81.4-0.90.5-0.6-0.4-0.40.6-0.9-0.7-0.81.20.9-0.91.0-1.11.1-1.10.8-0.81.1
Bone: cortical apparent density0.10.20.7-0.2-0.20.20.10.1-0.2-0.1-0.20.00.60.5-0.50.6-0.60.6-0.60.3-0.30.8
Bone: cortical area3.04.96.2-2.31.9-1.8-1.9-1.91.8-2.2-2.3-2.32.52.5-2.52.3-2.22.2-2.22.3-2.32.3
Bone: cortical porosity0.10.10.30.3-0.50.40.50.5-0.40.60.40.5-0.4-0.30.3-0.40.4-0.40.4-0.20.2-0.1
Bone: cortical porosity0.00.00.0-0.20.1-0.2-0.1-0.10.20.1-0.2-0.0-0.00.1-0.10.00.0-0.00.00.2-0.20.0
Bone: cortical thickness1.32.24.1-1.50.9-0.9-0.9-0.90.8-1.3-1.4-1.41.81.8-1.81.6-1.61.6-1.61.7-1.72.0
Bone: cortical thickness0.10.10.30.2-0.50.50.50.5-0.50.30.20.30.00.1-0.1-0.00.2-0.20.2-0.00.00.3
Bone: cortical tissue density0.10.10.5-0.1-0.20.20.20.2-0.2-0.0-0.10.10.40.4-0.40.5-0.50.5-0.50.2-0.20.7
Condit. Reinf. active minus inactive responses0.60.60.9-0.80.8-0.7-0.8-0.80.7-0.8-0.8-0.90.90.8-0.80.8-0.80.8-0.80.7-0.70.7
Condit. Reinf. active-inactive response ratio0.60.60.90.9-0.91.00.90.9-1.00.80.90.6-0.7-0.70.7-0.80.6-0.60.6-0.70.7-0.5
Condit. Reinf. active responses2.83.64.4-2.01.9-1.9-1.9-1.91.9-2.0-2.0-2.02.11.9-1.91.9-1.91.9-1.91.8-1.81.7
Condit. Reinf. inactive responses3.34.25.2-2.22.0-2.0-1.9-1.92.0-2.1-2.2-1.92.32.2-2.22.2-2.02.0-2.02.0-2.02.0
Incentive salience index mean4.15.26.2-2.42.5-2.4-2.5-2.52.4-2.5-2.4-2.42.42.2-2.22.2-2.22.2-2.22.1-2.01.7
Condit. Reinf. lever presses8.913.316.9-3.84.1-4.1-4.1-4.14.1-4.1-3.9-3.83.53.3-3.33.4-3.53.5-3.53.2-3.22.3
Condit. Reinf. active minus inactive responses0.50.81.3-0.90.8-0.7-0.7-0.70.7-1.0-0.9-0.81.20.9-0.91.0-1.11.0-1.00.8-0.80.9
Condit. Reinf. active-inactive response ratio0.00.00.2-0.0-0.10.10.10.1-0.1-0.30.00.00.50.1-0.10.3-0.30.3-0.30.1-0.10.4
Condit. Reinf. active responses2.02.94.1-1.71.7-1.5-1.5-1.51.5-1.9-1.7-1.62.01.7-1.71.8-1.81.8-1.81.6-1.51.4
Condit. Reinf. inactive responses3.24.75.8-2.32.1-1.9-1.9-1.91.9-2.2-2.3-2.02.42.4-2.42.4-2.32.3-2.32.2-2.11.9
Condit. Reinf. lever presses3.24.66.1-2.41.8-1.8-1.6-1.61.8-2.0-2.2-1.82.52.4-2.42.4-2.32.3-2.32.2-2.22.3
Condit. Reinf. lever reinforcers received2.53.54.7-2.01.9-1.7-1.7-1.71.7-2.1-1.9-1.72.21.9-1.92.0-2.02.0-2.01.7-1.61.5
Conditioned reinforcement - actives0.10.61.2-1.10.7-1.1-0.7-0.71.10.0-1.0-0.70.40.9-0.90.6-0.40.4-0.41.1-1.10.2
Conditioned reinforcement - inactives0.10.31.6-0.90.5-1.3-0.3-0.31.30.4-0.6-0.2-0.40.4-0.40.3-0.20.2-0.20.6-0.6-0.3
Conditioned locomotion0.10.10.3-0.40.5-0.4-0.4-0.40.4-0.0-0.4-0.6-0.10.3-0.3-0.10.3-0.30.30.5-0.5-0.1
Patch foraging indifference point 0 sec0.20.51.7-0.20.9-1.2-0.7-0.71.2-0.3-0.2-0.3-0.6-0.50.5-0.50.5-0.60.6-0.50.4-1.3
Patch foraging indifference point AUC3.27.611.1-2.72.9-2.6-3.0-3.02.5-3.3-2.8-3.22.92.5-2.52.6-2.72.7-2.72.6-2.62.2
Delay disc. indifference point, 0s delay1.11.22.11.0-0.90.60.80.8-0.61.10.90.8-1.2-1.11.1-1.31.4-1.41.4-1.11.1-1.4
Delay disc. indifference point, 16s delay1.11.53.11.1-0.80.40.90.9-0.40.91.10.8-1.5-1.51.5-1.61.4-1.41.4-1.51.4-1.8
Delay disc. indifference point, 2s delay0.20.30.5-0.50.2-0.1-0.3-0.30.1-0.2-0.5-0.70.60.7-0.70.4-0.50.6-0.60.7-0.70.5
Delay disc. indifference point, 24s delay0.20.40.80.6-0.70.40.80.8-0.40.30.60.9-0.3-0.70.7-0.60.5-0.40.4-0.70.6-0.4
Delay disc. indifference point, 4s delay0.30.41.00.7-0.51.00.50.5-1.00.40.6-0.0-0.4-0.50.5-0.70.7-0.70.7-0.40.4-0.3
Delay disc. indifference point, 8s delay0.00.10.20.4-0.30.40.10.1-0.40.00.3-0.1-0.0-0.20.2-0.40.3-0.30.3-0.30.2-0.1
Indifference point function ln k0.92.84.51.6-1.71.41.71.7-1.41.91.72.1-1.8-1.61.6-1.61.7-1.71.7-1.71.7-1.5
Indifference point function log k0.92.84.51.6-1.71.41.71.7-1.41.91.72.1-1.8-1.61.6-1.61.7-1.71.7-1.71.7-1.5
Patch foraging total patch changes 0 sec0.20.62.5-0.71.3-1.6-1.1-1.11.6-0.7-0.7-0.7-0.1-0.10.1-0.00.1-0.10.1-0.0-0.1-0.8
Patch foraging total patch changes 12 sec1.41.92.6-1.41.4-1.3-1.5-1.51.3-1.6-1.4-1.61.41.2-1.21.3-1.41.4-1.41.3-1.31.1
Patch foraging total patch changes 18 sec0.20.40.9-0.50.7-0.6-0.9-0.90.6-0.9-0.6-0.90.60.4-0.40.5-0.50.5-0.50.3-0.30.1
Patch foraging total patch changes 24 sec0.62.03.2-1.51.7-1.7-1.8-1.81.7-1.7-1.5-1.41.21.2-1.21.3-1.21.2-1.21.1-1.20.8
Patch foraging total patch changes 6 sec1.42.34.9-1.72.1-2.2-1.9-1.92.2-1.8-1.6-2.01.21.0-1.00.9-1.11.1-1.11.1-1.20.4
Patch foraging time to switch 0 sec0.72.64.01.7-2.01.92.02.0-1.91.91.71.8-1.2-1.31.3-1.31.4-1.31.3-1.41.3-0.9
Patch foraging water rate 0 sec0.41.42.9-1.21.7-1.6-1.5-1.51.6-1.5-1.2-1.30.90.8-0.80.9-0.90.9-0.90.9-0.80.4
Patch foraging water rate 12 sec0.00.00.2-0.30.5-0.1-0.2-0.20.1-0.1-0.10.0-0.2-0.00.0-0.00.1-0.00.0-0.00.1-0.3
Patch foraging water rate 18 sec0.40.81.5-1.00.6-0.5-0.4-0.40.5-0.7-0.8-0.50.91.1-1.11.2-1.21.2-1.21.1-1.01.1
Patch foraging water rate 24 sec0.10.10.2-0.2-0.10.50.30.3-0.50.1-0.0-0.30.40.4-0.40.3-0.40.5-0.50.2-0.00.5
Patch foraging water rate 6 sec1.31.92.5-1.61.5-1.3-1.5-1.51.3-1.2-1.5-1.31.21.5-1.51.4-1.41.4-1.41.3-1.20.9
Seeking ratio, delayed vs. immediate footshock2.53.65.4-1.71.9-1.4-2.1-2.11.4-2.3-1.9-1.92.11.9-1.92.2-2.02.0-2.01.8-1.71.6
Distance traveled before self-admin2.86.210.1-2.73.2-2.7-3.2-3.22.7-2.8-2.7-2.81.72.3-2.32.1-2.02.0-2.02.2-2.31.5
Distance traveled after self-admin2.85.06.4-2.52.2-1.9-2.2-2.21.9-1.8-2.4-2.01.82.5-2.52.4-2.22.2-2.22.5-2.52.1
Extensor digitorum longus weight5.421.426.0-5.14.9-5.1-4.9-4.95.1-4.8-5.0-5.04.34.4-4.44.4-4.34.3-4.34.5-4.53.4
Bone: elastic displacement5.87.39.42.9-3.13.03.13.1-3.02.82.92.9-2.4-2.52.5-2.52.5-2.52.5-2.52.5-1.6
Bone: elastic work1.52.04.41.4-2.12.02.12.1-2.01.71.51.6-0.9-0.80.8-0.91.0-1.01.0-0.80.80.2
Bone: endosteal estimation0.92.33.8-1.61.8-1.8-2.0-2.01.8-1.7-1.7-1.61.01.4-1.41.3-1.11.1-1.11.2-1.20.5
Bone: endosteal perimeter0.81.93.5-1.51.8-1.7-1.9-1.91.7-1.7-1.6-1.61.11.2-1.21.1-0.90.9-0.91.1-1.10.4
Epididymis fat weight0.10.81.3-0.80.8-0.6-0.8-0.80.6-1.1-0.9-1.11.10.9-0.90.9-0.80.8-0.80.8-0.70.9
Delta time in closed arm before/after self-admin0.50.41.3-0.20.10.6-0.1-0.1-0.7-0.7-0.2-0.70.70.7-0.70.8-0.90.9-0.90.5-0.61.1
Delta time in open arm before/after self-admin0.20.20.70.1-0.0-0.50.20.20.60.60.10.5-0.6-0.50.5-0.60.6-0.60.6-0.40.4-0.9
Diff in mean of infusions in LGA sessions0.10.10.2-0.4-0.2-0.40.40.40.40.2-0.3-0.30.30.4-0.4-0.10.1-0.10.10.3-0.40.4
Delay discount exponential model param0.71.01.6-1.10.8-1.0-0.8-0.81.0-0.7-1.0-0.40.91.0-1.01.3-1.21.1-1.11.1-1.01.1
Extinction: sum of active levers before priming1.62.44.11.3-1.50.91.71.7-0.91.71.41.3-2.0-1.51.5-1.91.7-1.71.7-1.41.4-1.7
Active lever presses in extinction session 60.50.50.90.7-0.80.40.90.9-0.40.40.70.6-0.9-0.80.8-0.80.9-0.90.9-0.70.6-0.7
Bone: final force2.23.64.5-2.11.9-2.0-1.7-1.71.9-1.9-2.0-2.11.91.9-1.91.8-1.81.8-1.82.0-2.01.7
Bone: final moment1.93.03.8-1.91.6-1.7-1.5-1.51.7-1.7-1.8-1.91.81.8-1.81.7-1.71.7-1.71.9-1.91.7
Food consumed during 24 hour testing period0.51.11.5-1.11.2-1.2-1.2-1.21.2-1.2-1.1-1.11.00.9-0.91.0-1.01.0-1.00.8-0.70.4
Glucose1.52.54.1-1.51.7-1.6-1.7-1.71.6-2.0-1.6-1.41.71.5-1.51.6-1.61.6-1.61.3-1.21.0
Heart weight0.30.51.2-0.80.7-0.8-0.6-0.60.8-1.1-0.7-0.70.90.6-0.60.5-0.50.5-0.50.7-0.70.7
Delay discount hyperbolic model param0.60.81.3-1.00.7-0.9-0.6-0.60.9-0.6-0.9-0.30.80.9-0.91.2-1.01.0-1.01.0-0.91.0
Intermittent access intake day 1-15 change0.31.72.4-1.61.2-1.5-1.1-1.11.5-1.2-1.4-0.51.31.3-1.31.5-1.21.2-1.21.4-1.41.3
Intermittent access intake escalation0.31.62.4-1.51.1-1.4-1.0-1.01.4-1.1-1.3-0.61.21.3-1.31.4-1.21.2-1.21.4-1.51.4
Intermittent access intake escalation 22.03.44.7-2.11.3-1.7-1.3-1.31.7-1.4-1.9-1.11.92.0-2.02.1-2.12.1-2.12.1-2.22.1
Intermitt. access day 1 inactive lever presses0.10.82.0-0.81.0-1.1-1.0-1.01.1-1.4-0.9-1.10.90.6-0.60.7-0.80.8-0.80.5-0.50.5
Intermitt. access day 15 inactive lever presses0.10.30.9-0.80.7-0.8-0.6-0.60.8-0.4-0.6-1.00.20.5-0.50.1-0.30.3-0.30.7-0.70.4
Intermitt. access escalation Index0.10.31.0-0.50.6-0.6-0.5-0.50.7-0.9-0.6-1.00.40.5-0.50.2-0.40.4-0.40.4-0.40.3
Intermittent access day 1 total infusions0.82.43.41.6-1.31.31.51.5-1.31.61.61.1-1.8-1.61.6-1.61.7-1.71.7-1.41.4-1.9
Intermittent access day 15 total infusions0.10.30.8-0.80.4-0.7-0.2-0.20.7-0.0-0.6-0.30.20.6-0.60.5-0.20.2-0.20.8-0.90.4
Intermittent access terminal intake (last 3 days)0.71.22.7-1.51.0-1.6-1.0-1.01.6-0.3-1.3-0.90.61.1-1.11.1-0.80.8-0.81.3-1.40.5
Intermittent access total infusions0.20.30.7-0.70.6-0.8-0.5-0.50.80.0-0.6-0.70.20.4-0.40.4-0.20.3-0.30.6-0.7-0.1
Intermittent access day 1 locomotion1.42.73.41.7-1.41.51.51.5-1.51.61.71.3-1.8-1.61.6-1.71.8-1.81.8-1.61.6-1.8
Intermittent access day 15 total locomotion0.51.92.61.4-1.21.31.31.3-1.31.51.41.4-1.6-1.31.3-1.51.5-1.51.5-1.31.3-1.4
Intermittent access total locomotion1.01.22.61.0-1.21.21.31.3-1.21.61.11.2-1.3-0.80.8-0.91.1-1.11.1-0.70.7-0.8
Intermittent access standard deviation0.10.61.0-0.80.8-1.0-0.8-0.81.0-0.7-0.8-0.70.80.6-0.60.7-0.70.7-0.70.7-0.80.4
Left kidney weight0.21.94.2-1.41.9-2.0-2.0-2.02.0-1.7-1.5-1.30.60.9-0.91.1-0.90.9-0.91.0-0.80.2
Right kidney weight0.21.32.7-1.41.4-1.6-1.3-1.31.6-1.3-1.3-0.90.61.0-1.00.9-0.70.7-0.71.1-1.00.7
Cocaine induced anxiety0.10.10.3-0.30.4-0.3-0.5-0.50.30.2-0.3-0.30.30.2-0.20.5-0.60.6-0.60.3-0.2-0.0
Post-drug Anxiety1.11.22.1-1.11.3-1.3-1.5-1.51.3-0.9-1.2-0.91.00.8-0.81.2-1.21.2-1.20.9-0.70.2
Baseline Anxiety0.30.50.9-0.80.6-0.6-0.5-0.50.6-1.0-0.7-0.50.80.7-0.70.8-0.70.7-0.70.8-0.70.7
Tail length1.26.38.9-2.42.7-2.1-2.8-2.82.1-3.0-2.6-2.82.32.5-2.52.7-2.52.5-2.52.5-2.32.0
Length with tail1.04.68.2-2.12.8-2.3-2.9-2.92.3-2.8-2.3-2.51.51.9-1.92.0-1.71.8-1.81.6-1.60.8
Length without tail0.00.20.7-0.20.7-0.6-0.7-0.70.6-0.4-0.3-0.1-0.3-0.10.1-0.10.2-0.20.2-0.30.2-0.9
Times rat made contact with spout0.70.81.0-1.00.8-0.8-0.7-0.70.8-0.7-0.9-0.80.80.9-0.91.0-1.01.0-1.01.0-1.01.0
Lifetime Intake0.20.30.8-0.70.8-0.9-0.7-0.70.90.0-0.6-0.7-0.00.4-0.40.4-0.10.1-0.10.6-0.6-0.4
Liver weight, left0.00.10.2-0.00.0-0.3-0.1-0.10.40.10.00.0-0.4-0.30.3-0.40.4-0.40.4-0.10.1-0.3
Liver weight, right0.30.51.10.7-0.91.00.80.8-1.01.00.70.9-0.6-0.40.4-0.30.4-0.40.4-0.50.5-0.4
Locomotor activity0.00.00.1-0.20.0-0.2-0.1-0.10.2-0.1-0.2-0.30.10.2-0.20.1-0.10.1-0.1-0.0-0.0-0.1
Locomotor testing distance0.10.21.10.3-0.10.00.00.0-0.00.40.30.1-0.5-0.50.5-0.60.5-0.50.5-0.70.7-1.1
Locomotor testing rearing0.51.82.7-1.51.5-1.6-1.5-1.51.6-1.1-1.5-1.61.31.3-1.31.2-1.31.3-1.31.1-1.00.4
Locomotion in novel chamber0.20.20.50.5-0.70.60.70.7-0.60.60.50.7-0.1-0.40.4-0.10.1-0.00.0-0.30.20.0
Locomotion in novel chamber post-restriction0.82.54.1-1.71.1-1.1-1.1-1.11.1-1.1-1.5-1.41.91.8-1.81.8-1.71.7-1.71.9-1.92.0
Fecal boli incidents, locomotor time 10.61.62.21.3-1.51.11.51.5-1.01.21.31.3-1.1-1.31.3-1.31.2-1.21.2-1.31.3-0.7
Change in fecal boli incidents, locomotor task0.40.41.1-0.61.0-0.8-0.9-0.90.8-0.8-0.7-1.00.30.5-0.50.3-0.30.3-0.30.3-0.3-0.0
Time >=10cm from walls, locomotor time 10.10.20.4-0.30.3-0.5-0.3-0.30.5-0.2-0.2-0.6-0.6-0.10.1-0.50.6-0.50.50.1-0.1-0.5
Bouts of movement, locomotor time 10.70.92.00.5-1.10.51.21.2-0.51.40.90.8-1.1-0.90.9-1.00.9-0.90.9-0.80.8-0.9
Total resting periods, locomotor time 11.11.32.80.8-1.51.01.51.5-1.01.71.21.1-1.2-1.01.0-1.11.0-1.01.0-0.90.9-0.8
Rest time, locomotor task time 10.61.03.00.7-1.61.71.71.7-1.71.21.00.9-0.4-0.30.3-0.30.2-0.20.2-0.10.10.8
Distance moved, locomotor task time 10.61.84.5-1.31.9-2.1-1.9-1.92.1-1.6-1.5-1.21.10.9-0.90.8-0.70.7-0.70.7-0.7-0.1
Vertical activity count, locomotor time 10.10.92.4-0.71.5-1.5-1.5-1.51.5-1.0-1.0-1.40.60.4-0.40.2-0.00.1-0.10.3-0.2-0.6
Time >=10cm from walls, locomotor time 20.00.00.10.10.2-0.2-0.1-0.10.2-0.20.0-0.2-0.1-0.20.2-0.20.1-0.00.00.1-0.20.2
Bouts of movement, locomotor time 20.30.92.3-1.11.0-1.0-1.1-1.11.0-0.7-1.0-1.50.80.9-0.90.8-0.80.8-0.80.9-0.90.4
Total resting periods, locomotor time 20.10.51.5-0.90.7-0.7-0.8-0.80.7-0.3-0.7-1.20.50.7-0.70.5-0.60.6-0.60.6-0.60.2
Rest time, locomotor task time 20.30.51.40.4-0.91.01.01.0-1.01.20.60.2-0.7-0.20.2-0.60.7-0.60.6-0.30.1-0.1
Distance moved, locomotor task time 20.50.61.5-0.50.6-0.6-0.6-0.60.6-0.9-0.7-0.31.20.7-0.71.0-1.01.0-1.00.7-0.71.1
Vertical activity count, locomotor time 20.10.30.8-0.30.8-0.7-0.7-0.70.8-0.9-0.6-0.60.90.4-0.40.5-0.40.4-0.40.4-0.30.4
Light reinforcement 10.31.44.2-1.21.9-2.0-1.9-1.92.0-1.4-1.2-0.80.40.3-0.30.4-0.40.4-0.40.5-0.6-0.5
Light reinforcement 20.30.61.8-0.21.1-1.3-1.3-1.31.3-0.6-0.5-0.3-0.6-0.40.4-0.30.4-0.40.4-0.20.1-1.3
Bone: marrow area1.02.53.9-1.71.9-1.9-2.0-2.01.9-1.8-1.8-1.71.21.5-1.51.5-1.31.3-1.31.4-1.40.8
Bone: maximum diameter2.55.06.0-2.42.2-2.0-2.2-2.22.0-2.3-2.4-2.52.42.4-2.42.3-2.12.1-2.12.2-2.21.9
Bone: maximum force3.87.59.6-3.12.7-2.9-2.6-2.62.9-2.7-2.9-2.92.62.8-2.82.6-2.62.6-2.62.8-2.82.4
Bone: maximum moment3.36.27.9-2.82.4-2.5-2.3-2.32.5-2.4-2.6-2.62.42.6-2.62.4-2.42.4-2.42.7-2.62.3
Mean time between licks in bursts0.10.50.60.8-0.80.80.80.8-0.80.70.80.7-0.6-0.70.7-0.70.7-0.70.7-0.80.7-0.5
Mean num. licks in bursts1.33.44.41.9-2.01.82.12.1-1.81.92.02.1-1.8-1.81.8-1.81.7-1.71.7-1.81.8-1.4
Cd content in liver1.21.41.9-1.31.3-1.2-1.3-1.31.2-1.2-1.3-0.91.11.3-1.31.2-1.00.9-0.91.2-1.40.9
Co content in liver0.50.61.40.7-0.30.40.30.3-0.40.60.71.2-0.8-0.90.9-0.80.8-0.80.8-0.90.9-1.1
Cu content in liver1.31.62.21.3-1.41.51.41.4-1.51.51.31.4-1.2-1.11.1-1.21.2-1.31.3-1.00.9-0.8
Fe content in liver0.81.02.11.1-0.50.70.50.5-0.70.90.90.9-1.2-1.11.1-1.20.9-1.01.0-1.21.3-1.5
K content in liver0.40.40.70.5-0.20.30.20.2-0.30.50.50.8-0.8-0.70.7-0.90.8-0.80.8-0.60.6-0.7
Mg content in liver1.21.31.81.2-1.11.11.11.1-1.11.11.21.4-1.2-1.21.2-1.31.3-1.21.2-1.11.1-0.9
Mn content in liver2.02.23.3-1.81.3-1.3-1.3-1.31.3-1.1-1.6-1.51.31.8-1.81.4-1.21.3-1.31.8-1.81.7
Na content in liver0.80.92.11.0-1.01.01.01.0-1.01.21.01.5-1.0-0.80.8-0.90.8-1.01.0-0.70.7-0.6
Rb content in liver5.05.97.72.8-2.32.62.32.3-2.62.52.62.6-2.2-2.52.5-2.32.2-2.22.2-2.62.5-2.1
Se content in liver3.44.15.0-2.21.9-1.8-1.9-1.91.8-1.8-2.1-2.22.02.2-2.21.7-2.02.1-2.12.2-2.12.0
Sr content in liver0.30.30.8-0.80.5-0.6-0.5-0.50.6-0.4-0.6-0.9-0.10.6-0.6-0.00.0-0.20.20.7-0.80.5
Zn content in liver0.00.00.2-0.1-0.2-0.00.20.20.0-0.20.00.30.30.1-0.1-0.0-0.10.1-0.10.2-0.20.4
Bone: minimum diameter0.00.00.20.2-0.40.40.30.3-0.40.20.20.20.00.0-0.0-0.00.1-0.10.1-0.10.10.0
Time in familiar zone, hab. session 10.30.41.10.1-1.00.90.90.9-0.90.60.40.40.20.2-0.20.2-0.20.2-0.20.4-0.41.1
Time in novel zone, hab. session 12.22.55.31.6-0.70.80.80.8-0.81.21.41.2-1.8-1.81.8-1.81.9-1.91.9-1.91.9-2.3
Total zone transitions, hab. session 10.00.00.10.2-0.30.20.30.3-0.2-0.00.20.2-0.0-0.20.2-0.20.1-0.10.1-0.30.3-0.1
Total locomotion distance, hab. session 10.40.51.5-0.70.2-0.3-0.2-0.20.3-0.6-0.6-0.41.00.9-0.90.8-0.90.9-0.90.8-0.81.2
Locomotion velocity, hab. session 11.52.13.0-1.61.1-1.1-1.0-1.01.1-1.5-1.4-1.21.71.6-1.61.5-1.61.6-1.61.5-1.61.7
Time in familiar zone, hab. session 20.50.61.70.8-1.11.31.21.2-1.30.90.80.4-0.2-0.30.3-0.50.4-0.40.4-0.40.30.3
Time in novel zone, hab. session 21.21.33.31.0-0.50.40.40.4-0.41.00.91.1-1.7-1.31.3-1.31.4-1.41.4-1.41.3-1.8
Total zone transitions, hab. session 20.30.30.8-0.50.9-0.8-0.9-0.90.8-0.9-0.6-0.50.50.2-0.20.4-0.40.4-0.40.1-0.1-0.2
Total locomotion distance, hab. session 20.60.81.3-0.90.9-0.9-1.0-1.00.9-1.1-0.9-0.91.10.8-0.80.9-0.90.9-0.90.7-0.80.8
Locomotion velocity, hab. session 20.81.01.7-1.01.0-0.9-1.0-1.00.9-1.2-1.0-0.91.30.9-0.91.0-1.11.1-1.10.9-0.90.9
Novel to familiar place preference ratio3.14.15.72.0-1.61.61.61.6-1.62.02.02.0-2.3-2.22.2-2.22.4-2.42.4-2.02.1-2.2
Novelty place preference4.15.26.82.3-1.91.91.91.9-1.92.32.32.2-2.5-2.42.4-2.52.6-2.62.6-2.22.3-2.3
Time in novel zone, NPP test5.16.28.02.5-2.12.12.12.1-2.12.62.52.4-2.7-2.62.6-2.72.8-2.82.8-2.42.6-2.6
Total zone transitions, NPP test0.30.41.1-0.61.0-1.0-1.0-1.01.0-1.0-0.7-0.50.50.3-0.30.5-0.50.5-0.50.2-0.3-0.1
Total locomotion distance, NPP test1.11.52.8-1.21.6-1.5-1.5-1.51.5-1.7-1.3-1.21.21.0-1.01.0-1.01.0-1.00.9-1.00.6
Locomotion velocity, NPP test1.52.23.7-1.51.7-1.7-1.7-1.71.7-1.9-1.6-1.41.51.3-1.31.3-1.41.4-1.41.1-1.30.9
Intraocular pressure1.83.04.3-1.71.9-2.1-2.0-2.02.1-1.9-1.9-2.11.71.6-1.61.5-1.41.5-1.51.4-1.50.9
Delta distance traveled before/after self-admin0.10.10.3-0.3-0.1-0.10.00.00.10.1-0.20.10.30.3-0.30.5-0.50.5-0.50.4-0.20.4
Delta ambulatory time before/after self-admin0.10.10.70.1-0.50.20.50.5-0.20.70.30.8-0.2-0.10.10.1-0.10.1-0.1-0.10.2-0.0
Parametrial fat weight0.30.71.11.0-0.40.70.50.5-0.70.30.90.4-0.8-1.01.0-0.90.9-0.90.9-1.01.0-0.9
Pavlov. Cond. lever latency7.19.011.13.2-3.33.33.33.3-3.33.23.33.0-2.9-2.92.9-2.92.8-2.82.8-2.72.7-2.1
Pavlov. Cond. magazine entry latency0.40.50.8-0.70.7-0.7-0.7-0.70.7-0.9-0.7-0.80.90.6-0.60.6-0.70.7-0.70.5-0.40.6
Pavlov. Cond. change in total contacts2.72.94.0-1.72.0-1.9-2.0-2.01.9-1.9-1.8-2.01.61.5-1.51.5-1.61.6-1.61.4-1.41.1
Pavlov. Cond. index score3.34.25.0-2.12.2-2.2-2.2-2.22.2-2.2-2.2-2.12.22.0-2.02.0-2.02.0-2.01.8-1.81.6
Pavlov. Cond. latency score3.13.94.6-2.12.1-2.1-2.1-2.12.1-2.1-2.1-2.02.01.9-1.91.9-1.91.9-1.91.8-1.71.5
Pavlov. Cond. lever contacts6.78.19.7-2.93.1-3.1-3.1-3.13.1-3.0-3.1-2.82.82.7-2.72.8-2.72.7-2.72.6-2.62.1
Pavlov. Cond. magazine entry number0.60.71.20.8-0.80.80.80.8-0.81.00.81.0-1.1-0.80.8-0.80.9-0.90.9-0.70.7-0.9
Pavlov. Cond. intertrial magazine entries0.30.30.5-0.60.5-0.6-0.5-0.50.6-0.5-0.6-0.70.60.6-0.60.6-0.50.5-0.50.5-0.50.4
Pavlov. Cond. lever-magazine prob. diff.3.44.24.8-2.12.1-2.1-2.1-2.12.1-2.2-2.2-2.12.22.0-2.02.0-2.12.1-2.11.9-1.81.7
Pavlov. Cond. response bias3.84.76.0-2.22.3-2.3-2.3-2.32.3-2.5-2.3-2.32.32.1-2.12.1-2.12.1-2.11.9-1.91.6
Pavlov. Cond. lever latency3.04.25.42.3-1.71.61.61.6-1.61.92.11.9-2.2-2.32.3-2.32.3-2.22.2-2.22.1-2.2
Pavlov. Cond. magazine entry latency0.10.10.30.2-0.40.50.50.5-0.50.40.30.4-0.1-0.00.0-0.00.1-0.10.1-0.10.10.0
Pavlov. Cond. change in total contacts0.61.53.4-1.20.6-0.4-0.4-0.40.4-1.0-1.0-1.01.71.5-1.51.5-1.51.5-1.51.3-1.31.9
Pavlov. Cond. index score0.40.61.3-0.80.3-0.2-0.2-0.20.2-0.6-0.7-0.51.01.0-1.01.0-1.00.9-0.90.9-0.81.1
Pavlov. Cond. latency score0.50.91.7-1.00.5-0.3-0.3-0.30.3-0.7-0.8-0.61.11.2-1.21.2-1.11.1-1.11.0-1.01.3
Pavlov. Cond. lever contacts2.13.14.2-2.01.5-1.3-1.3-1.31.3-1.7-1.8-1.61.92.1-2.12.0-2.01.9-1.91.9-1.91.9
Pavlov. Cond. magazine entry number0.40.51.20.7-0.10.00.10.10.00.40.50.3-0.9-1.01.0-1.00.9-0.90.9-0.80.8-1.1
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.50.6-0.6-0.6-0.60.6-0.5-0.5-0.50.40.3-0.30.3-0.30.3-0.30.5-0.40.3
Pavlov. Cond. lever-magazine prob. diff.0.40.61.5-0.80.3-0.1-0.2-0.20.1-0.6-0.7-0.51.01.1-1.11.1-1.01.0-1.00.9-0.91.2
Pavlov. Cond. response bias1.21.72.6-1.40.9-0.7-0.8-0.80.7-1.1-1.3-1.01.51.6-1.61.6-1.51.5-1.51.4-1.41.6
Time in closed arm before self-admin0.50.81.51.2-1.01.20.80.8-1.20.91.10.8-0.4-1.01.0-0.70.7-0.70.7-0.91.1-0.6
Time in closed arm after self-admin0.20.20.80.5-0.60.90.50.5-0.90.20.50.40.2-0.20.20.1-0.10.1-0.1-0.20.20.4
Time in open arm before self-admin0.70.81.9-1.11.3-1.4-1.2-1.21.4-1.2-1.1-1.10.40.7-0.70.5-0.30.3-0.30.6-0.70.1
Time in open arm after self-admin0.80.93.0-1.21.3-1.7-1.1-1.11.7-0.8-1.1-1.10.30.7-0.70.3-0.40.4-0.40.7-0.8-0.1
Bone: periosteal estimation1.84.35.1-2.22.1-2.1-2.2-2.22.0-2.2-2.3-2.21.92.2-2.22.1-1.91.9-1.92.0-2.01.5
Bone: periosteal perimeter0.51.01.7-1.11.2-1.2-1.3-1.31.2-1.1-1.1-1.20.90.9-0.90.8-0.70.7-0.70.8-0.80.3
Bone: post-yield work1.83.14.9-2.02.2-2.2-2.1-2.12.2-2.0-1.9-2.01.51.5-1.51.4-1.41.4-1.41.6-1.60.9
Progressive ratio test 1 active lever presses0.10.21.1-0.00.2-0.4-0.1-0.10.40.60.00.2-0.7-0.30.3-0.20.4-0.40.4-0.10.1-1.0
Progressive ratio test 1 breakpoint0.10.10.8-0.10.3-0.5-0.1-0.10.50.5-0.10.0-0.6-0.20.2-0.10.3-0.30.30.0-0.1-0.9
Progressive ratio test 1 inactive lever presses0.41.02.9-1.11.5-1.7-1.4-1.41.7-0.9-1.1-1.50.10.6-0.60.4-0.50.5-0.50.7-0.7-0.3
Progressive ratio test 2 active lever presses0.20.31.70.20.1-0.2-0.0-0.00.20.90.1-0.0-1.0-0.40.4-0.60.7-0.70.7-0.30.3-1.3
Progressive ratio test 2 breakpoint0.30.41.80.30.1-0.10.00.00.11.00.2-0.0-1.1-0.40.4-0.70.8-0.80.8-0.30.3-1.4
Progressive ratio test 2 inactive lever presses0.20.61.7-1.00.9-1.3-0.8-0.81.3-0.2-0.9-0.90.40.7-0.70.4-0.40.4-0.40.7-0.70.0
Incentive Sensitization - Responses0.00.10.3-0.30.5-0.4-0.6-0.60.40.4-0.4-0.5-0.20.3-0.30.1-0.10.1-0.10.1-0.1-0.6
Incentive Sensitization - Breakpoint0.00.10.4-0.10.3-0.3-0.4-0.40.30.5-0.3-0.4-0.30.2-0.2-0.0-0.00.0-0.0-0.00.0-0.7
Sum of active levers in priming session hrs 5-64.44.15.92.0-1.61.11.61.6-1.11.71.91.7-2.4-2.32.3-2.42.4-2.42.4-2.12.3-2.4
Progressive ratio0.10.20.50.7-0.30.70.30.3-0.70.10.60.4-0.4-0.70.7-0.30.2-0.20.2-0.60.6-0.5
Food seeking constrained by brief footshock6.48.013.0-2.93.6-3.3-3.6-3.63.3-3.1-3.0-2.82.22.4-2.42.7-2.72.6-2.62.3-2.41.4
Seeking ratio, punishment vs. effort1.94.25.8-2.42.3-2.4-2.3-2.32.4-1.8-2.3-2.01.62.1-2.11.9-1.81.7-1.72.0-2.01.5
Retroperitoneal fat weight0.52.24.21.7-1.82.01.81.8-2.01.31.71.5-0.9-1.31.3-1.11.1-1.11.1-1.41.4-0.6
Reaction time number correct0.00.10.20.20.1-0.1-0.2-0.20.1-0.10.1-0.20.0-0.30.3-0.40.1-0.10.1-0.20.4-0.5
Reaction time mean minus median0.21.03.5-1.0-0.2-0.20.20.20.1-0.7-0.6-0.71.11.2-1.21.0-1.11.1-1.11.4-1.41.9
Reaction time mean minus median AUC0.31.83.7-1.50.6-0.8-0.5-0.50.8-1.1-1.2-1.21.31.7-1.71.5-1.51.5-1.51.8-1.81.9
Reaction time num false alarms0.20.40.9-1.00.2-0.8-0.1-0.10.8-0.0-0.7-0.20.20.8-0.80.6-0.50.5-0.51.0-0.90.7
Reaction time num false alarms AUC0.51.12.3-1.50.9-1.5-0.7-0.71.5-0.7-1.2-0.80.51.1-1.10.9-0.90.8-0.81.3-1.30.8
Reaction time trials correct on left0.00.10.20.20.1-0.1-0.2-0.20.1-0.10.1-0.20.0-0.30.3-0.40.1-0.10.1-0.20.4-0.5
Reaction time trials on left0.00.10.30.30.00.0-0.0-0.0-0.0-0.00.2-0.1-0.1-0.40.4-0.50.2-0.20.2-0.30.5-0.6
Reaction time mean0.61.23.11.1-1.81.61.81.8-1.61.11.21.3-0.6-0.60.6-0.60.6-0.60.6-0.60.50.3
Reaction time mean AUC0.51.33.41.1-1.81.71.81.8-1.71.21.21.4-0.7-0.60.6-0.60.6-0.60.6-0.50.50.3
Median of all reaction times1.93.04.81.9-2.22.22.22.2-2.21.81.92.0-1.4-1.51.5-1.41.4-1.41.4-1.41.4-0.6
Reaction time omissions1.72.73.61.6-1.71.61.81.8-1.51.51.81.3-1.6-1.71.7-1.81.9-1.81.8-1.41.3-1.2
Reaction time false alarm rate0.20.30.7-0.90.1-0.7-0.0-0.00.70.0-0.6-0.10.00.7-0.70.5-0.40.3-0.30.8-0.80.6
Reaction time premature initiation rate1.82.84.61.7-2.02.02.12.1-2.01.71.81.9-1.3-1.41.4-1.31.5-1.51.5-1.51.5-0.8
Reaction time premature initiations0.82.43.51.7-1.81.81.91.9-1.81.51.71.6-1.2-1.41.4-1.41.4-1.41.4-1.51.6-1.0
Std. dev. reaction times0.10.41.5-0.1-0.90.61.01.0-0.60.10.20.20.40.4-0.40.3-0.30.4-0.40.5-0.61.2
Reaction time trials completed0.00.10.30.30.00.0-0.0-0.0-0.0-0.00.2-0.1-0.1-0.40.4-0.50.2-0.20.2-0.30.5-0.6
Reaction time trials AUC0.00.10.30.3-0.00.1-0.0-0.0-0.10.00.2-0.1-0.1-0.40.4-0.50.3-0.30.3-0.30.5-0.5
Run reversals in cocaine runway, females0.10.20.60.3-0.80.40.60.6-0.40.30.40.80.0-0.20.2-0.0-0.0-0.00.0-0.10.10.4
Run reversals in cocaine runway, males0.10.10.30.3-0.30.60.30.3-0.60.30.3-0.0-0.3-0.10.1-0.20.2-0.20.2-0.1-0.0-0.2
Latency to leave start box in cocaine runway0.70.91.2-0.91.0-0.6-1.1-1.10.6-1.0-1.0-1.11.01.1-1.11.0-0.80.8-0.81.1-1.11.1
Latency to leave start box in cocaine runway, F0.20.20.70.5-0.20.40.10.1-0.40.30.4-0.1-0.5-0.50.5-0.70.8-0.80.8-0.50.5-0.4
Latency to leave start box in cocaine runway, M3.63.54.5-2.02.1-1.6-2.1-2.11.6-1.8-2.0-1.51.62.0-2.02.1-1.71.7-1.71.9-1.91.6
Std. dev. time between licks in bursts0.20.30.50.6-0.60.70.70.7-0.70.70.60.5-0.5-0.50.5-0.50.5-0.50.5-0.60.5-0.4
Total sessions with >9 infusions0.40.41.1-0.80.9-1.0-0.9-0.91.0-0.2-0.8-0.5-0.00.5-0.50.7-0.20.2-0.20.6-0.7-0.4
Short access day 1 total inactive lever presses0.51.02.5-1.11.5-1.6-1.5-1.51.6-1.1-1.1-1.20.50.6-0.60.5-0.60.6-0.60.6-0.7-0.2
Short access day 10 total inactive lever presses0.21.42.1-1.41.3-1.5-1.1-1.11.5-1.2-1.2-1.21.11.1-1.10.9-1.31.3-1.31.1-1.11.0
Short access day 1 total infusions0.40.72.0-0.91.2-1.4-1.2-1.21.4-0.5-1.0-0.8-0.00.5-0.50.6-0.20.2-0.20.5-0.6-0.6
Short access day 10 total infusions0.10.21.30.40.0-0.00.00.00.00.20.3-0.0-0.7-0.50.5-0.40.6-0.60.6-0.50.4-1.1
Short access total infusions0.10.21.1-0.20.5-0.6-0.5-0.50.60.3-0.2-0.3-0.6-0.10.1-0.00.4-0.40.40.0-0.0-1.1
Short access day 1 locomotion1.22.13.01.5-1.31.11.21.2-1.11.21.41.1-1.6-1.51.5-1.61.6-1.61.6-1.61.5-1.7
Short access day 10 total locomotion0.31.32.71.2-1.51.61.61.6-1.61.21.31.4-0.9-0.80.8-0.70.7-0.70.7-0.80.8-0.5
Short access total locomotion0.60.91.31.0-0.90.91.01.0-0.90.61.00.9-1.2-0.90.9-0.91.0-1.01.0-0.90.9-1.1
One hour access (0.3 mA shock)0.20.30.9-0.70.7-0.9-0.6-0.60.9-0.0-0.6-0.5-0.10.4-0.40.20.1-0.10.10.5-0.5-0.4
Compulsive drug intake0.00.10.30.1-0.20.30.10.1-0.3-0.1-0.00.10.60.2-0.20.3-0.20.2-0.2-0.10.00.5
One hour access (shock baseline)0.10.20.9-0.30.7-0.8-0.6-0.60.80.1-0.3-0.4-0.5-0.20.2-0.20.4-0.40.40.0-0.0-1.0
Social response proportion2.43.14.32.1-2.01.92.12.1-1.91.61.91.6-1.2-1.71.7-1.71.7-1.61.6-1.71.8-1.0
Social responses0.40.61.0-0.70.9-0.8-0.7-0.70.8-0.9-0.8-1.01.00.8-0.80.6-0.70.7-0.70.7-0.50.6
Social time0.10.10.20.2-0.1-0.40.10.10.40.10.20.40.1-0.50.5-0.30.3-0.30.3-0.20.3-0.3
Soleus weight0.20.72.90.60.3-0.4-0.3-0.30.4-0.20.40.3-0.9-1.01.0-0.90.9-0.90.9-1.11.1-1.7
Bone: stiffness4.99.011.4-3.43.0-3.1-2.9-2.93.1-3.0-3.2-3.12.93.0-3.02.9-2.92.9-2.93.1-3.12.6
Tibialis anterior weight7.726.433.4-5.35.6-5.6-5.8-5.85.6-5.7-5.5-5.74.84.8-4.84.8-4.74.8-4.84.7-4.73.4
Time to tail flick, vehicle, before self-admin1.21.53.41.5-1.41.81.31.3-1.91.11.41.2-0.8-1.11.1-0.90.8-0.80.8-1.11.1-0.6
Time to tail flick, vehicle, after self-admin0.00.10.30.10.10.5-0.0-0.0-0.5-0.1-0.1-0.00.30.3-0.30.4-0.30.3-0.30.1-0.20.4
Time to tail flick, test, before self-admin0.50.51.2-0.50.8-0.1-0.8-0.80.1-0.5-0.6-1.10.80.8-0.80.7-0.90.9-0.90.8-0.70.6
Time to tail flick, test, after self-admin1.01.13.4-0.70.3-0.1-0.3-0.30.1-1.2-0.7-1.01.81.1-1.11.2-1.31.3-1.31.0-1.01.6
Delta time to tail flick, vehicle, before/after SA0.50.61.0-0.90.8-1.0-0.8-0.81.0-0.6-0.9-0.70.70.7-0.70.7-0.70.7-0.70.7-0.70.4
Delta time to tail flick, test, before/after SA0.10.20.60.4-0.70.50.70.7-0.50.20.40.50.2-0.20.2-0.10.1-0.10.1-0.30.10.4
Tibia length0.10.20.7-0.10.8-0.5-0.8-0.80.5-0.2-0.3-0.6-0.3-0.00.0-0.30.4-0.40.4-0.10.2-0.7
Ambulatory time before self-admin1.54.67.9-2.42.8-2.6-2.8-2.82.6-2.4-2.4-2.51.51.9-1.91.7-1.61.6-1.61.8-1.91.0
Ambulatory time after self-admin1.32.03.1-1.81.7-1.8-1.7-1.71.8-1.2-1.6-1.20.91.4-1.41.3-1.11.1-1.11.4-1.40.9
Bone: tissue strength0.20.20.4-0.50.4-0.5-0.3-0.30.5-0.4-0.4-0.50.50.3-0.30.3-0.40.4-0.40.6-0.60.6
Total heroin consumption1.11.42.91.0-0.70.60.90.9-0.61.00.90.4-1.7-1.11.1-1.61.5-1.51.5-1.11.1-1.6
Bone: trabecular number0.81.62.4-1.31.0-1.1-0.8-0.81.1-1.3-1.2-1.31.51.2-1.21.3-1.51.5-1.51.3-1.31.4
Bone: trabecular spacing0.10.10.2-0.30.1-0.2-0.2-0.20.2-0.1-0.3-0.40.30.4-0.40.3-0.20.2-0.20.4-0.40.5
Bone: trabecular thickness0.20.20.50.4-0.60.60.60.6-0.60.50.50.7-0.3-0.30.3-0.30.4-0.40.4-0.40.4-0.1
Bone: trabecular tissue density3.45.97.0-2.62.5-2.5-2.6-2.62.5-2.4-2.7-2.62.32.5-2.52.3-2.22.2-2.22.5-2.51.9
Water consumed over 24 hours0.91.72.3-1.51.3-1.5-1.2-1.21.5-1.2-1.4-1.31.21.3-1.31.3-1.31.3-1.31.2-1.31.0
Number of responses in last shaping day0.60.83.00.60.4-0.2-0.4-0.40.30.10.30.2-1.0-0.90.9-1.01.4-1.41.4-1.00.9-1.7