Fam219a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Fam219a 0.56 0.16 0.0e+00 0.36 0.38 0.4 0.4 1.0e-19 3.1e-21 1.0e-22 1.8e-22
2 Brain mRNA stability Fam219a 0.04 0.03 4.7e-04 0.04 0.03 0.03 0.04 6.0e-05 1.0e-03 3.7e-04 1.2e-04
3 BLA alternative TSS NM_001415979.1 0.07 0.05 1.4e-03 0.03 0.03 0.01 0.03 8.7e-03 1.1e-02 9.0e-02 7.1e-03
4 Liver gene expression Fam219a 0.04 0.04 1.4e-03 0.02 0.01 0.01 0.01 6.3e-03 1.4e-02 7.2e-03 3.8e-02
5 pVTA gene expression Fam219a 0.1 0.06 2.3e-08 0.12 0.09 0.09 0.1 7.2e-10 1.1e-07 9.0e-08 1.3e-08
6 BLA isoform ratio NM_001415979.1 0.06 0.05 3.4e-03 0.03 0.02 0.01 0.02 7.0e-03 4.2e-02 5.6e-02 3.3e-02
7 Brain gene expression Fam219a 0.2 0.1 0.0e+00 0.15 0.1 0.16 0.12 3.6e-14 6.6e-10 3.8e-15 1.9e-11
8 BLA alternative TSS XM_006238103.5 0.08 0.05 8.8e-04 0.03 0.03 0.04 0.04 6.3e-03 6.7e-03 5.0e-03 5.7e-03
9 NAcc gene expression Fam219a 0.1 0.06 3.9e-16 0.1 0.09 0.11 0.1 9.8e-15 1.7e-13 1.4e-16 2.3e-15
10 PL alternative TSS NM_001415979.1 0.04 0.05 2.4e-03 0.03 0.02 0.01 0.02 6.8e-04 1.1e-03 9.0e-03 1.1e-03
11 BLA alternative TSS NM_001415979.1 0.06 0.05 3.0e-03 0.03 0.02 0.01 0.03 1.4e-02 2.0e-02 1.2e-01 1.5e-02
12 BLA alternative TSS XM_006238103.5 0.07 0.05 1.4e-03 0.03 0.03 0.01 0.03 9.9e-03 1.4e-02 1.0e-01 1.3e-02
13 Adipose mRNA stability Fam219a 0.03 0.02 1.7e-03 0.02 0.02 0.02 0.02 8.9e-04 1.5e-03 2.4e-03 2.3e-03
14 PL alternative TSS XM_006238103.5 0.04 0.03 6.4e-04 0.03 0.03 0.03 0.03 1.4e-04 3.5e-04 2.8e-04 2.7e-04
15 PL alternative TSS NM_001415979.1 0.04 0.04 1.3e-03 0.03 0.03 0.02 0.03 3.2e-04 5.1e-04 1.1e-03 7.1e-04
16 PL alternative TSS XM_006238103.5 0.03 0.03 5.8e-03 0.02 0.02 0.01 0.02 1.5e-03 2.4e-03 2.0e-02 2.8e-03
17 PL gene expression Fam219a 0.41 0.16 0.0e+00 0.16 0.16 0.17 0.17 1.5e-17 3.7e-17 1.4e-18 9.0e-19
18 IC gene expression Fam219a 0.68 0.15 3.5e-09 0.21 0.18 0.15 0.17 4.6e-09 3.7e-08 6.7e-07 1.0e-07
19 RMTg gene expression Fam219a 0.23 0.15 4.0e-04 0.07 0.08 0.11 0.07 7.8e-03 4.8e-03 6.1e-04 5.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.22.12.91.5-1.1-1.31.01.0-1.31.51.41.4-1.7-1.41.4-1.51.7-1.71.71.51.5-1.6
Area under the delay curve0.91.11.8-1.20.91.0-0.8-0.81.0-0.8-1.0-0.51.01.1-1.11.3-1.21.2-1.2-1.2-1.11.2
BMI with tail1.44.96.12.5-2.0-2.41.91.9-2.42.42.32.0-2.4-2.22.2-2.12.2-2.22.22.32.2-2.0
BMI without tail1.85.47.22.4-2.2-2.32.22.2-2.32.72.42.4-2.5-2.32.3-2.42.4-2.42.42.42.1-2.1
Body weight2.611.215.63.5-3.8-3.63.73.7-3.63.93.63.5-3.1-3.23.2-3.33.1-3.13.13.13.0-2.2
Weight adjusted by age0.10.10.40.1-0.6-0.50.60.6-0.50.30.30.10.20.0-0.00.1-0.30.2-0.20.0-0.00.2
Bone surface0.61.21.61.1-1.1-1.01.11.1-1.01.21.11.2-1.1-1.01.0-1.11.1-1.11.11.01.0-0.7
Bone volume0.61.11.41.1-0.9-0.90.90.9-0.91.11.01.2-1.2-1.01.0-1.01.1-1.11.11.11.1-0.9
Breakpoint value in progressive ratio session2.02.45.9-1.30.50.2-0.8-0.80.1-0.8-1.1-0.21.91.8-1.82.3-2.22.2-2.2-1.6-1.72.4
Number of licking bursts4.87.78.92.9-2.7-2.72.82.8-2.62.72.93.0-2.8-2.82.8-2.82.8-2.82.82.82.8-2.4
Context. condit. distance diff. score0.10.10.3-0.40.50.5-0.4-0.40.5-0.3-0.4-0.20.30.3-0.30.3-0.10.1-0.1-0.3-0.30.2
Locomotion velocity, session 10.50.62.7-0.1-0.9-0.90.90.9-0.90.60.10.10.50.7-0.70.5-0.40.4-0.4-0.8-0.81.6
Locomotion distance, session 10.10.20.70.1-0.6-0.60.60.6-0.60.60.20.20.10.3-0.30.2-0.10.1-0.1-0.4-0.40.8
Locomotion velocity, session 22.02.33.31.6-1.4-1.41.31.3-1.41.71.61.3-1.8-1.61.6-1.61.6-1.61.61.51.4-1.5
Locomotion distance, session 21.52.13.41.5-1.8-1.71.81.8-1.71.81.61.5-1.4-1.21.2-1.21.3-1.31.31.11.0-0.5
Locomotion velocity, session 30.10.10.50.1-0.5-0.50.40.4-0.50.30.20.10.40.1-0.10.2-0.10.1-0.1-0.3-0.30.7
Locomotion distance, session 31.41.52.61.3-1.6-1.51.51.5-1.51.61.31.3-0.9-1.01.0-1.01.0-1.01.00.91.0-0.5
Stereotopy head waving bouts, day 30.20.20.80.2-0.5-0.50.50.5-0.5-0.30.20.10.90.1-0.10.3-0.60.6-0.60.0-0.00.7
Stereotopy head waving duration, day 30.10.10.70.2-0.2-0.30.20.2-0.3-0.60.1-0.00.80.0-0.00.2-0.50.5-0.50.10.10.5
Locomotion velocity, session 70.10.10.1-0.10.20.1-0.3-0.30.1-0.3-0.2-0.30.30.2-0.20.2-0.30.3-0.3-0.2-0.20.2
Locomotion distance, session 70.10.10.30.4-0.5-0.60.40.4-0.60.50.40.5-0.3-0.20.2-0.10.2-0.20.20.30.2-0.0
Stereotopy head waving bouts, day 71.51.72.61.4-1.5-1.51.61.6-1.51.21.51.1-0.6-1.21.2-1.41.1-1.11.11.31.3-0.7
Stereotopy head waving duration, day 71.01.21.71.2-1.2-1.21.31.3-1.20.91.20.9-0.5-1.11.1-1.20.9-0.90.91.21.2-0.7
Locomotion velocity, session 80.10.10.7-0.1-0.3-0.30.40.4-0.30.1-0.0-0.10.30.4-0.40.2-0.10.1-0.1-0.5-0.50.8
Locomotion distance, session 80.10.10.30.2-0.5-0.40.60.6-0.40.50.20.3-0.00.0-0.0-0.00.2-0.20.2-0.1-0.10.5
Degree of sensitization distance0.70.71.2-0.81.00.9-1.0-1.00.9-1.1-0.9-0.80.70.8-0.80.9-0.90.9-0.9-0.6-0.70.5
Degree of sensitization stereotypy1.61.72.21.4-1.3-1.31.41.4-1.31.31.41.1-1.0-1.31.3-1.51.3-1.31.31.31.3-1.0
Conditioned locomotion0.10.10.5-0.2-0.2-0.20.30.3-0.2-0.0-0.0-0.10.40.3-0.30.2-0.40.4-0.4-0.4-0.40.7
Cocaine response after cond. corrected1.72.13.4-1.40.80.8-1.0-1.00.8-1.4-1.3-1.21.71.7-1.71.8-1.81.7-1.7-1.5-1.41.8
Cocaine response after cond. not corrected1.51.83.4-1.20.60.6-0.8-0.80.6-1.2-1.2-1.11.61.5-1.51.7-1.71.7-1.7-1.4-1.41.9
Cocaine response before conditioning0.91.11.31.1-1.0-1.00.90.9-1.01.01.11.0-1.1-1.11.1-1.11.1-1.11.11.00.9-0.9
Saline control response1.11.53.01.5-1.7-1.71.61.6-1.71.21.41.0-0.6-1.01.0-1.10.8-0.80.81.00.9-0.1
Bone: connectivity density0.50.81.40.9-0.5-0.60.40.4-0.60.90.70.8-1.2-0.90.9-1.01.1-1.11.10.80.8-1.1
Bone: cortical apparent density0.10.20.70.20.20.2-0.1-0.10.20.10.2-0.0-0.6-0.50.5-0.60.6-0.60.60.30.3-0.8
Bone: cortical area3.24.96.22.3-1.9-1.81.91.9-1.82.22.32.3-2.5-2.52.5-2.32.2-2.22.22.32.3-2.3
Bone: cortical porosity0.10.10.3-0.30.50.4-0.5-0.50.4-0.6-0.4-0.50.40.3-0.30.4-0.40.4-0.4-0.2-0.20.1
Bone: cortical porosity0.00.00.00.2-0.1-0.20.10.1-0.2-0.10.20.00.0-0.10.1-0.0-0.00.0-0.00.20.2-0.0
Bone: cortical thickness1.32.24.11.5-0.9-0.90.90.9-0.81.31.41.4-1.8-1.81.8-1.61.6-1.61.61.71.7-2.0
Bone: cortical thickness0.10.10.3-0.20.50.5-0.5-0.50.5-0.3-0.2-0.3-0.0-0.10.10.0-0.20.2-0.2-0.0-0.0-0.3
Bone: cortical tissue density0.10.10.50.10.20.2-0.2-0.20.20.00.1-0.1-0.4-0.40.4-0.50.5-0.50.50.20.2-0.7
Condit. Reinf. active minus inactive responses0.60.60.90.8-0.8-0.70.80.8-0.70.80.80.9-0.9-0.80.8-0.80.8-0.80.80.70.7-0.7
Condit. Reinf. active-inactive response ratio0.60.60.9-0.90.91.0-0.9-0.91.0-0.8-0.9-0.60.70.7-0.70.8-0.60.6-0.6-0.7-0.70.5
Condit. Reinf. active responses2.93.64.42.0-1.9-1.91.91.9-1.92.02.02.0-2.1-1.91.9-1.91.9-1.91.91.81.8-1.7
Condit. Reinf. inactive responses3.44.25.22.2-2.0-2.01.91.9-2.02.12.21.9-2.3-2.22.2-2.22.0-2.02.02.02.0-2.0
Incentive salience index mean4.35.26.22.4-2.5-2.42.52.5-2.42.52.42.4-2.4-2.22.2-2.22.2-2.22.22.12.0-1.7
Condit. Reinf. lever presses9.413.316.93.8-4.1-4.14.14.1-4.14.13.93.8-3.5-3.33.3-3.43.5-3.53.53.23.2-2.3
Condit. Reinf. active minus inactive responses0.60.81.30.9-0.8-0.70.70.7-0.71.00.90.8-1.2-0.90.9-1.01.1-1.01.00.80.8-0.9
Condit. Reinf. active-inactive response ratio0.00.00.20.00.10.1-0.1-0.10.10.3-0.0-0.0-0.5-0.10.1-0.30.3-0.30.30.10.1-0.4
Condit. Reinf. active responses2.12.94.11.7-1.7-1.51.51.5-1.51.91.71.6-2.0-1.71.7-1.81.8-1.81.81.61.5-1.4
Condit. Reinf. inactive responses3.64.75.82.3-2.1-1.91.91.9-1.92.22.32.0-2.4-2.42.4-2.42.3-2.32.32.32.1-1.9
Condit. Reinf. lever presses3.34.66.12.4-1.8-1.81.61.6-1.82.02.21.8-2.5-2.42.4-2.42.3-2.32.32.22.2-2.3
Condit. Reinf. lever reinforcers received2.53.54.72.0-1.9-1.71.71.7-1.72.11.91.7-2.2-1.91.9-2.02.0-2.02.01.71.6-1.5
Conditioned reinforcement - actives0.30.61.21.1-0.7-1.10.70.7-1.10.01.00.7-0.4-0.90.9-0.60.4-0.40.41.11.1-0.2
Conditioned reinforcement - inactives0.20.31.60.9-0.5-1.30.30.3-1.3-0.40.60.20.4-0.40.4-0.30.2-0.20.20.60.60.3
Conditioned locomotion0.10.10.30.4-0.5-0.40.40.4-0.40.00.40.60.1-0.30.30.1-0.30.3-0.30.50.50.1
Patch foraging indifference point 0 sec0.30.51.70.2-0.9-1.20.70.7-1.20.30.20.30.60.5-0.50.5-0.50.6-0.6-0.5-0.41.3
Patch foraging indifference point AUC5.37.611.12.7-2.9-2.63.03.0-2.53.32.83.2-2.9-2.52.5-2.62.7-2.72.72.62.6-2.2
Delay disc. indifference point, 0s delay1.11.22.1-1.00.90.6-0.8-0.80.6-1.1-0.9-0.81.21.1-1.11.3-1.41.4-1.4-1.1-1.11.4
Delay disc. indifference point, 16s delay1.41.53.1-1.10.80.4-0.9-0.90.4-0.9-1.1-0.81.51.5-1.51.6-1.41.4-1.4-1.5-1.41.8
Delay disc. indifference point, 2s delay0.20.30.50.5-0.2-0.10.30.3-0.10.20.50.7-0.6-0.70.7-0.40.5-0.60.60.70.7-0.5
Delay disc. indifference point, 24s delay0.30.40.8-0.60.70.4-0.8-0.80.4-0.3-0.6-0.90.30.7-0.70.6-0.50.4-0.4-0.7-0.60.4
Delay disc. indifference point, 4s delay0.40.41.0-0.70.51.0-0.5-0.51.0-0.4-0.60.00.40.5-0.50.7-0.70.7-0.7-0.4-0.40.3
Delay disc. indifference point, 8s delay0.10.10.2-0.40.30.4-0.1-0.10.4-0.0-0.30.10.00.2-0.20.4-0.30.3-0.3-0.3-0.20.1
Indifference point function ln k1.62.84.6-1.61.71.4-1.7-1.71.4-1.9-1.7-2.11.81.6-1.61.6-1.71.7-1.7-1.7-1.71.5
Indifference point function log k1.62.84.6-1.61.71.4-1.7-1.71.4-1.9-1.7-2.11.81.6-1.61.6-1.71.7-1.7-1.7-1.71.5
Patch foraging total patch changes 0 sec0.30.62.50.7-1.3-1.61.11.1-1.60.70.70.70.10.1-0.10.0-0.10.1-0.10.00.10.8
Patch foraging total patch changes 12 sec1.51.92.61.4-1.4-1.31.51.5-1.31.61.41.6-1.4-1.21.2-1.31.4-1.41.41.31.3-1.1
Patch foraging total patch changes 18 sec0.20.40.90.5-0.7-0.60.90.9-0.60.90.60.9-0.6-0.40.4-0.50.5-0.50.50.40.3-0.1
Patch foraging total patch changes 24 sec1.22.03.21.5-1.7-1.71.81.8-1.71.71.51.4-1.2-1.21.2-1.31.2-1.21.21.11.2-0.8
Patch foraging total patch changes 6 sec1.52.34.91.7-2.1-2.21.91.9-2.21.81.62.0-1.2-1.01.0-0.91.1-1.11.11.11.2-0.4
Patch foraging time to switch 0 sec1.22.64.0-1.72.01.9-2.0-2.01.9-1.9-1.7-1.81.21.3-1.31.3-1.41.3-1.3-1.4-1.30.9
Patch foraging water rate 0 sec0.71.42.91.2-1.7-1.61.51.5-1.61.51.21.3-0.9-0.80.8-0.90.9-0.90.90.90.8-0.4
Patch foraging water rate 12 sec0.00.00.20.3-0.5-0.10.20.2-0.10.10.1-0.00.20.0-0.00.0-0.10.0-0.0-0.0-0.10.3
Patch foraging water rate 18 sec0.50.81.51.0-0.6-0.50.40.4-0.50.70.80.5-0.9-1.11.1-1.21.2-1.21.21.01.0-1.1
Patch foraging water rate 24 sec0.10.10.20.20.10.5-0.3-0.30.5-0.10.00.3-0.4-0.40.4-0.30.4-0.50.50.20.0-0.5
Patch foraging water rate 6 sec1.31.92.51.6-1.5-1.31.51.5-1.31.21.51.3-1.2-1.51.5-1.41.4-1.41.41.31.2-0.9
Seeking ratio, delayed vs. immediate footshock3.03.65.31.7-1.9-1.42.12.1-1.42.31.91.9-2.1-1.91.9-2.22.0-2.02.01.81.7-1.6
Distance traveled before self-admin4.76.210.12.7-3.2-2.73.23.2-2.72.82.72.8-1.7-2.32.3-2.12.0-2.02.02.22.3-1.5
Distance traveled after self-admin4.15.06.42.5-2.2-1.92.22.2-1.91.82.42.0-1.8-2.52.5-2.42.2-2.22.22.52.5-2.1
Extensor digitorum longus weight5.521.526.05.1-4.9-5.14.94.9-5.14.85.05.0-4.3-4.44.4-4.44.3-4.34.34.64.5-3.4
Bone: elastic displacement6.37.39.4-2.93.13.0-3.1-3.13.0-2.8-2.9-2.92.42.5-2.52.5-2.52.5-2.5-2.5-2.51.6
Bone: elastic work1.52.04.4-1.42.12.0-2.1-2.12.0-1.7-1.5-1.60.90.8-0.80.9-1.01.0-1.0-0.8-0.8-0.2
Bone: endosteal estimation1.02.33.81.6-1.8-1.82.02.0-1.81.71.71.6-1.0-1.41.4-1.31.1-1.11.11.21.2-0.5
Bone: endosteal perimeter0.91.93.51.5-1.8-1.71.91.9-1.71.71.61.6-1.1-1.21.2-1.10.9-0.90.91.11.1-0.4
Epididymis fat weight0.20.81.30.8-0.8-0.60.80.8-0.61.10.91.1-1.1-0.90.9-0.90.8-0.80.80.80.7-0.9
Delta time in closed arm before/after self-admin0.50.41.30.2-0.10.60.10.10.70.70.20.7-0.7-0.70.7-0.80.9-0.90.90.50.6-1.1
Delta time in open arm before/after self-admin0.20.20.7-0.10.0-0.5-0.2-0.2-0.6-0.6-0.1-0.50.60.5-0.50.6-0.60.6-0.6-0.4-0.40.9
Diff in mean of infusions in LGA sessions0.10.10.20.40.2-0.4-0.4-0.4-0.4-0.20.30.3-0.3-0.40.40.1-0.10.1-0.10.30.4-0.4
Delay discount exponential model param0.91.01.61.1-0.8-1.00.80.8-1.00.71.00.4-0.9-1.01.0-1.31.2-1.11.11.11.0-1.1
Extinction: sum of active levers before priming2.22.44.1-1.31.50.9-1.7-1.70.9-1.7-1.4-1.32.01.5-1.51.9-1.71.7-1.7-1.4-1.41.7
Active lever presses in extinction session 60.60.50.9-0.70.80.4-0.9-0.90.4-0.4-0.7-0.60.90.8-0.80.8-0.90.9-0.9-0.7-0.60.7
Bone: final force2.23.64.52.1-1.9-2.01.71.7-1.91.92.02.1-1.9-1.91.9-1.81.8-1.81.82.02.0-1.7
Bone: final moment1.93.03.81.9-1.6-1.71.51.5-1.71.71.81.9-1.8-1.81.8-1.71.7-1.71.71.91.9-1.7
Food consumed during 24 hour testing period0.81.11.51.1-1.2-1.21.21.2-1.21.21.11.1-1.0-0.90.9-1.01.0-1.01.00.80.7-0.4
Glucose1.62.54.11.5-1.7-1.61.71.7-1.62.01.61.4-1.7-1.51.5-1.61.6-1.61.61.31.2-1.0
Heart weight0.30.51.20.8-0.7-0.80.60.6-0.81.10.70.7-0.9-0.60.6-0.50.5-0.50.50.70.7-0.7
Delay discount hyperbolic model param0.70.81.31.0-0.7-0.90.60.6-0.90.60.90.3-0.8-0.90.9-1.21.0-1.01.01.00.9-1.0
Intermittent access intake day 1-15 change0.81.72.41.6-1.2-1.51.11.1-1.51.21.40.5-1.3-1.31.3-1.51.2-1.21.21.41.4-1.3
Intermittent access intake escalation0.81.62.41.5-1.1-1.41.01.0-1.41.11.30.6-1.2-1.31.3-1.41.2-1.21.21.41.5-1.4
Intermittent access intake escalation 23.03.44.72.1-1.3-1.71.31.3-1.71.41.91.1-1.9-2.02.0-2.12.1-2.12.12.12.2-2.1
Intermitt. access day 1 inactive lever presses0.20.82.00.8-1.0-1.11.01.0-1.11.40.91.1-0.9-0.60.6-0.70.8-0.80.80.50.5-0.5
Intermitt. access day 15 inactive lever presses0.20.30.90.8-0.7-0.80.60.6-0.80.40.61.0-0.2-0.50.5-0.10.3-0.30.30.70.7-0.4
Intermitt. access escalation Index0.20.31.00.5-0.6-0.60.50.5-0.70.80.61.0-0.4-0.50.5-0.20.4-0.40.40.40.4-0.3
Intermittent access day 1 total infusions1.52.43.4-1.61.31.3-1.5-1.51.3-1.6-1.6-1.11.81.6-1.61.6-1.71.7-1.7-1.4-1.41.9
Intermittent access day 15 total infusions0.20.30.80.8-0.4-0.70.20.2-0.70.00.60.3-0.2-0.60.6-0.50.2-0.20.20.80.9-0.4
Intermittent access terminal intake (last 3 days)0.91.22.71.5-1.0-1.61.01.0-1.60.31.30.9-0.6-1.11.1-1.10.8-0.80.81.31.4-0.5
Intermittent access total infusions0.20.30.70.7-0.6-0.80.50.5-0.8-0.00.60.7-0.2-0.40.4-0.40.2-0.30.30.60.70.1
Intermittent access day 1 locomotion2.12.73.4-1.71.41.5-1.5-1.51.5-1.6-1.7-1.31.81.6-1.61.7-1.81.8-1.8-1.6-1.61.8
Intermittent access day 15 total locomotion1.11.92.6-1.41.21.3-1.3-1.31.3-1.5-1.4-1.41.61.3-1.31.5-1.51.5-1.5-1.3-1.31.4
Intermittent access total locomotion1.01.22.6-1.01.21.2-1.3-1.31.2-1.6-1.1-1.21.30.8-0.80.9-1.11.1-1.1-0.7-0.70.8
Intermittent access standard deviation0.30.61.00.8-0.8-1.00.80.8-1.00.70.80.7-0.8-0.60.6-0.70.7-0.70.70.70.8-0.4
Left kidney weight0.41.94.21.4-1.9-2.02.02.0-2.01.71.51.3-0.6-0.90.9-1.10.9-0.90.91.00.8-0.2
Right kidney weight0.31.32.71.4-1.4-1.61.31.3-1.61.31.30.9-0.6-1.01.0-0.90.7-0.70.71.11.0-0.7
Cocaine induced anxiety0.10.10.30.3-0.4-0.30.50.5-0.3-0.10.30.3-0.3-0.20.2-0.50.6-0.60.60.30.20.0
Post-drug Anxiety1.11.22.11.1-1.3-1.31.51.5-1.30.91.20.9-1.0-0.80.8-1.21.2-1.21.20.90.7-0.2
Baseline Anxiety0.40.50.90.8-0.6-0.60.50.5-0.61.00.70.5-0.8-0.70.7-0.80.7-0.70.70.80.7-0.7
Tail length1.66.38.82.4-2.7-2.12.82.8-2.13.02.62.8-2.3-2.52.5-2.72.5-2.52.52.52.3-2.0
Length with tail1.14.68.22.1-2.8-2.32.92.9-2.32.82.32.5-1.5-1.91.9-2.01.7-1.81.81.61.6-0.8
Length without tail0.10.20.70.2-0.7-0.60.70.7-0.60.40.30.10.30.1-0.10.1-0.20.2-0.2-0.3-0.20.9
Times rat made contact with spout0.70.81.01.0-0.8-0.80.70.7-0.80.70.90.8-0.8-0.90.9-1.01.0-1.01.01.01.0-1.0
Lifetime Intake0.30.30.80.7-0.8-0.90.70.7-0.9-0.00.60.70.0-0.40.4-0.40.1-0.10.10.60.60.4
Liver weight, left0.00.10.20.0-0.0-0.30.10.1-0.4-0.1-0.0-0.00.40.3-0.30.4-0.40.4-0.4-0.1-0.10.3
Liver weight, right0.30.51.1-0.70.91.0-0.8-0.81.0-1.0-0.7-0.90.60.4-0.40.3-0.40.4-0.4-0.5-0.50.4
Locomotor activity0.00.00.10.2-0.0-0.20.10.1-0.20.10.20.3-0.1-0.20.2-0.10.1-0.10.1-0.00.00.1
Locomotor testing distance0.10.21.1-0.30.10.0-0.0-0.00.0-0.4-0.3-0.10.50.5-0.50.6-0.50.5-0.5-0.7-0.71.1
Locomotor testing rearing0.91.82.71.5-1.5-1.61.51.5-1.61.11.51.6-1.3-1.31.3-1.21.3-1.31.31.11.0-0.4
Locomotion in novel chamber0.20.20.5-0.50.70.6-0.7-0.70.6-0.6-0.5-0.70.10.4-0.40.1-0.10.0-0.0-0.3-0.2-0.0
Locomotion in novel chamber post-restriction1.52.54.11.7-1.1-1.11.11.1-1.11.11.51.4-1.9-1.81.8-1.81.7-1.71.71.91.9-2.0
Fecal boli incidents, locomotor time 11.11.62.2-1.31.51.1-1.5-1.51.0-1.2-1.3-1.31.11.3-1.31.3-1.21.2-1.2-1.3-1.30.7
Change in fecal boli incidents, locomotor task0.40.41.10.6-1.0-0.80.90.9-0.80.80.71.0-0.3-0.50.5-0.30.3-0.30.30.30.30.0
Time >=10cm from walls, locomotor time 10.20.20.40.3-0.3-0.50.30.3-0.50.20.20.60.60.1-0.10.5-0.60.5-0.50.10.10.5
Bouts of movement, locomotor time 10.80.92.0-0.51.10.5-1.2-1.20.5-1.4-0.9-0.81.10.9-0.91.0-0.90.9-0.9-0.8-0.80.9
Total resting periods, locomotor time 11.21.32.8-0.81.51.0-1.5-1.51.0-1.7-1.2-1.11.21.0-1.01.1-1.01.0-1.0-0.9-0.90.8
Rest time, locomotor task time 10.81.03.0-0.71.61.7-1.7-1.71.7-1.2-1.0-0.90.40.3-0.30.3-0.20.2-0.2-0.1-0.1-0.8
Distance moved, locomotor task time 11.21.84.51.3-1.9-2.11.91.9-2.11.61.51.2-1.1-0.90.9-0.80.7-0.70.70.70.70.1
Vertical activity count, locomotor time 10.40.92.40.7-1.5-1.51.51.5-1.51.01.01.5-0.6-0.40.4-0.20.0-0.10.10.30.20.6
Time >=10cm from walls, locomotor time 20.00.00.1-0.1-0.2-0.20.10.1-0.20.2-0.00.20.10.2-0.20.2-0.10.0-0.00.10.2-0.2
Bouts of movement, locomotor time 20.60.92.31.1-1.0-1.01.11.1-1.00.71.01.5-0.8-0.90.9-0.80.8-0.80.80.90.9-0.4
Total resting periods, locomotor time 20.30.51.50.9-0.7-0.70.80.8-0.70.30.71.2-0.5-0.70.7-0.50.6-0.60.60.60.6-0.2
Rest time, locomotor task time 20.40.51.4-0.40.91.0-1.0-1.01.0-1.2-0.6-0.20.70.2-0.20.6-0.70.6-0.6-0.3-0.10.1
Distance moved, locomotor task time 20.50.61.50.5-0.6-0.60.60.6-0.60.90.70.3-1.2-0.70.7-1.01.0-1.01.00.70.7-1.1
Vertical activity count, locomotor time 20.20.30.80.3-0.8-0.70.70.7-0.80.90.60.6-0.9-0.40.4-0.50.4-0.40.40.40.3-0.4
Light reinforcement 10.61.44.21.2-1.9-2.01.91.9-2.01.41.20.8-0.4-0.30.3-0.40.4-0.40.40.50.60.5
Light reinforcement 20.40.61.80.2-1.1-1.31.31.3-1.30.60.50.30.60.4-0.40.3-0.40.4-0.4-0.2-0.11.3
Bone: marrow area1.22.53.91.7-1.9-1.92.02.0-1.91.81.81.7-1.2-1.51.5-1.51.3-1.31.31.41.4-0.8
Bone: maximum diameter2.75.06.02.4-2.2-2.02.22.2-2.02.32.42.5-2.4-2.42.4-2.32.1-2.12.12.22.2-1.9
Bone: maximum force4.27.59.63.1-2.7-2.92.62.6-2.92.72.92.9-2.6-2.82.8-2.62.6-2.62.62.82.8-2.4
Bone: maximum moment3.56.27.92.8-2.4-2.52.32.3-2.52.42.62.6-2.4-2.62.6-2.42.4-2.42.42.72.6-2.3
Mean time between licks in bursts0.20.50.6-0.80.80.8-0.8-0.80.8-0.7-0.8-0.70.60.7-0.70.7-0.70.7-0.7-0.8-0.70.5
Mean num. licks in bursts2.23.44.4-1.92.01.8-2.1-2.11.8-1.9-2.0-2.11.81.8-1.81.8-1.71.7-1.7-1.8-1.81.4
Cd content in liver1.21.41.91.3-1.3-1.21.31.3-1.21.21.30.9-1.1-1.31.3-1.21.0-0.90.91.21.4-0.9
Co content in liver0.50.61.4-0.70.30.4-0.3-0.30.4-0.6-0.7-1.20.80.9-0.90.8-0.80.8-0.8-0.9-0.91.1
Cu content in liver1.31.62.2-1.31.41.5-1.4-1.41.5-1.5-1.3-1.41.21.1-1.11.2-1.21.3-1.3-1.0-0.90.8
Fe content in liver0.81.02.1-1.10.50.7-0.5-0.50.7-0.9-0.9-0.91.21.1-1.11.2-0.91.0-1.0-1.2-1.31.5
K content in liver0.40.40.7-0.50.20.3-0.2-0.20.3-0.5-0.5-0.80.80.7-0.70.9-0.80.8-0.8-0.6-0.60.7
Mg content in liver1.31.31.8-1.21.11.1-1.1-1.11.1-1.1-1.2-1.41.21.2-1.21.3-1.31.2-1.2-1.1-1.10.9
Mn content in liver2.02.23.31.8-1.3-1.31.31.3-1.31.11.61.5-1.3-1.81.8-1.41.2-1.31.31.81.8-1.7
Na content in liver0.91.02.1-1.01.01.0-1.0-1.01.0-1.2-1.0-1.51.00.8-0.80.9-0.81.0-1.0-0.7-0.70.6
Rb content in liver5.05.97.7-2.82.32.6-2.3-2.32.6-2.5-2.6-2.62.22.5-2.52.3-2.22.2-2.2-2.6-2.52.1
Se content in liver3.44.15.02.2-1.9-1.81.91.9-1.81.82.12.2-2.0-2.22.2-1.72.0-2.12.12.22.1-2.0
Sr content in liver0.30.30.80.8-0.5-0.60.50.5-0.60.40.60.90.1-0.60.60.0-0.00.2-0.20.70.8-0.5
Zn content in liver0.00.00.20.10.2-0.0-0.2-0.2-0.00.2-0.0-0.3-0.3-0.10.10.00.1-0.10.10.20.2-0.4
Bone: minimum diameter0.00.00.2-0.20.40.4-0.3-0.30.4-0.2-0.2-0.2-0.0-0.00.00.0-0.10.1-0.1-0.1-0.1-0.0
Time in familiar zone, hab. session 10.40.41.1-0.11.00.9-0.9-0.90.9-0.6-0.4-0.4-0.2-0.20.2-0.20.2-0.20.20.40.4-1.1
Time in novel zone, hab. session 12.52.55.3-1.60.70.8-0.8-0.80.8-1.2-1.4-1.21.81.8-1.81.8-1.91.9-1.9-1.9-1.92.3
Total zone transitions, hab. session 10.00.00.1-0.20.30.2-0.3-0.30.20.0-0.2-0.20.00.2-0.20.2-0.10.1-0.1-0.3-0.30.1
Total locomotion distance, hab. session 10.40.51.50.7-0.2-0.30.20.2-0.30.60.60.4-1.0-0.90.9-0.80.9-0.90.90.80.8-1.2
Locomotion velocity, hab. session 11.52.13.01.6-1.1-1.11.01.0-1.11.51.41.2-1.7-1.61.6-1.51.6-1.61.61.51.6-1.7
Time in familiar zone, hab. session 20.50.61.7-0.81.11.3-1.2-1.21.3-0.9-0.8-0.40.20.3-0.30.5-0.40.4-0.4-0.4-0.3-0.3
Time in novel zone, hab. session 21.31.33.3-1.00.50.4-0.4-0.40.4-1.0-0.9-1.11.71.3-1.31.3-1.41.4-1.4-1.4-1.31.8
Total zone transitions, hab. session 20.30.30.80.5-0.9-0.80.90.9-0.80.90.60.5-0.5-0.20.2-0.40.4-0.40.40.10.10.2
Total locomotion distance, hab. session 20.60.81.30.9-0.9-0.91.01.0-0.91.10.90.9-1.1-0.80.8-0.90.9-0.90.90.70.8-0.8
Locomotion velocity, hab. session 20.81.01.71.0-1.0-0.91.01.0-0.91.21.00.9-1.3-0.90.9-1.01.1-1.11.10.90.9-0.9
Novel to familiar place preference ratio3.84.15.7-2.01.61.6-1.6-1.61.6-2.0-2.0-1.92.32.2-2.22.2-2.42.4-2.4-2.0-2.12.2
Novelty place preference4.95.26.8-2.31.91.9-1.9-1.91.9-2.3-2.3-2.22.52.4-2.42.5-2.62.6-2.6-2.2-2.32.3
Time in novel zone, NPP test5.86.28.0-2.52.12.1-2.1-2.12.1-2.6-2.5-2.42.72.6-2.62.7-2.82.8-2.8-2.4-2.62.6
Total zone transitions, NPP test0.30.41.10.6-1.0-1.01.01.0-1.01.00.70.5-0.5-0.30.3-0.50.5-0.50.50.20.30.1
Total locomotion distance, NPP test1.11.52.81.2-1.6-1.51.51.5-1.51.71.31.2-1.2-1.01.0-1.01.0-1.01.00.91.0-0.6
Locomotion velocity, NPP test1.52.23.71.5-1.7-1.71.71.7-1.71.91.61.4-1.5-1.31.3-1.31.4-1.41.41.21.3-0.9
Intraocular pressure2.13.04.31.7-1.9-2.12.02.0-2.11.91.92.1-1.7-1.61.6-1.51.4-1.51.51.41.5-0.9
Delta distance traveled before/after self-admin0.10.10.30.30.1-0.1-0.0-0.0-0.1-0.10.2-0.1-0.3-0.30.3-0.50.5-0.50.50.40.2-0.4
Delta ambulatory time before/after self-admin0.10.10.7-0.10.50.2-0.5-0.50.2-0.7-0.3-0.80.20.1-0.1-0.10.1-0.10.1-0.1-0.20.0
Parametrial fat weight0.30.71.1-1.00.40.7-0.5-0.50.7-0.3-0.9-0.40.81.0-1.00.9-0.90.9-0.9-1.0-1.00.9
Pavlov. Cond. lever latency7.29.011.1-3.23.33.3-3.3-3.33.3-3.2-3.3-3.02.92.9-2.92.9-2.82.8-2.8-2.7-2.72.1
Pavlov. Cond. magazine entry latency0.40.50.80.7-0.7-0.70.70.7-0.70.90.70.8-0.9-0.60.6-0.60.7-0.70.70.50.4-0.6
Pavlov. Cond. change in total contacts2.72.94.01.7-2.0-1.92.02.0-1.91.91.82.0-1.6-1.51.5-1.51.6-1.61.61.41.4-1.1
Pavlov. Cond. index score3.34.25.02.1-2.2-2.22.22.2-2.22.22.22.1-2.2-2.02.0-2.02.0-2.02.01.81.8-1.6
Pavlov. Cond. latency score3.13.94.62.1-2.1-2.12.12.1-2.12.12.12.0-2.0-1.91.9-1.91.9-1.91.91.81.7-1.5
Pavlov. Cond. lever contacts6.88.19.72.9-3.1-3.13.13.1-3.13.03.12.8-2.8-2.72.7-2.82.7-2.72.72.62.6-2.1
Pavlov. Cond. magazine entry number0.60.71.2-0.80.80.8-0.8-0.80.8-1.0-0.8-1.01.10.8-0.80.8-0.90.9-0.9-0.7-0.70.9
Pavlov. Cond. intertrial magazine entries0.30.30.50.6-0.5-0.60.50.5-0.60.50.60.7-0.6-0.60.6-0.60.5-0.50.50.50.5-0.4
Pavlov. Cond. lever-magazine prob. diff.3.44.24.82.1-2.1-2.12.12.1-2.12.22.22.1-2.2-2.02.0-2.02.1-2.12.11.91.8-1.7
Pavlov. Cond. response bias3.84.76.02.2-2.3-2.32.32.3-2.32.52.32.3-2.3-2.12.1-2.12.1-2.12.11.91.9-1.6
Pavlov. Cond. lever latency3.14.25.4-2.31.71.6-1.6-1.61.6-1.9-2.1-1.92.22.3-2.32.3-2.32.2-2.2-2.2-2.12.2
Pavlov. Cond. magazine entry latency0.10.10.3-0.20.40.5-0.5-0.50.5-0.4-0.3-0.40.10.0-0.00.0-0.10.1-0.1-0.1-0.1-0.0
Pavlov. Cond. change in total contacts1.01.53.41.2-0.6-0.40.40.4-0.41.01.00.9-1.7-1.51.5-1.51.5-1.51.51.31.3-1.9
Pavlov. Cond. index score0.40.61.30.8-0.3-0.20.20.2-0.20.60.70.5-1.0-1.01.0-1.01.0-0.90.90.90.8-1.1
Pavlov. Cond. latency score0.70.91.71.0-0.5-0.30.30.3-0.30.70.80.6-1.1-1.21.2-1.21.1-1.11.11.01.0-1.3
Pavlov. Cond. lever contacts2.33.14.22.0-1.5-1.31.31.3-1.31.71.81.6-1.9-2.12.1-2.02.0-1.91.91.91.9-1.9
Pavlov. Cond. magazine entry number0.40.51.2-0.70.10.0-0.1-0.1-0.0-0.4-0.5-0.30.91.0-1.01.0-0.90.9-0.9-0.8-0.81.1
Pavlov. Cond. intertrial magazine entries0.10.20.40.5-0.6-0.60.60.6-0.60.50.50.5-0.4-0.30.3-0.30.3-0.30.30.50.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.50.61.50.8-0.3-0.10.20.2-0.10.60.70.5-1.0-1.11.1-1.11.0-1.01.00.90.9-1.2
Pavlov. Cond. response bias1.31.72.61.4-0.9-0.70.80.8-0.71.11.31.0-1.5-1.61.6-1.61.5-1.51.51.41.4-1.6
Time in closed arm before self-admin0.60.81.5-1.21.01.2-0.8-0.81.2-0.9-1.1-0.80.41.0-1.00.7-0.70.7-0.7-0.9-1.10.6
Time in closed arm after self-admin0.20.20.8-0.50.60.9-0.5-0.50.9-0.2-0.5-0.4-0.20.2-0.2-0.10.1-0.10.1-0.2-0.2-0.4
Time in open arm before self-admin0.80.81.91.1-1.3-1.41.21.2-1.41.21.11.1-0.4-0.70.7-0.50.3-0.30.30.60.7-0.1
Time in open arm after self-admin0.80.93.01.2-1.3-1.71.11.1-1.70.81.11.1-0.3-0.70.7-0.30.4-0.40.40.70.80.1
Bone: periosteal estimation2.04.35.12.2-2.1-2.12.22.2-2.02.22.32.2-1.9-2.22.2-2.11.9-1.91.92.02.0-1.5
Bone: periosteal perimeter0.61.01.71.1-1.2-1.21.31.3-1.21.11.11.2-0.9-0.90.9-0.80.7-0.70.70.80.8-0.3
Bone: post-yield work2.13.14.92.0-2.2-2.22.12.1-2.22.01.92.0-1.5-1.51.5-1.41.4-1.41.41.61.6-0.9
Progressive ratio test 1 active lever presses0.10.21.10.0-0.2-0.40.10.1-0.4-0.6-0.0-0.20.70.3-0.30.2-0.40.4-0.4-0.1-0.11.0
Progressive ratio test 1 breakpoint0.10.10.80.1-0.3-0.50.10.1-0.5-0.40.1-0.00.60.2-0.20.1-0.30.3-0.30.00.10.9
Progressive ratio test 1 inactive lever presses0.71.02.91.1-1.5-1.71.41.4-1.70.91.11.5-0.1-0.60.6-0.40.5-0.50.50.70.70.3
Progressive ratio test 2 active lever presses0.30.31.7-0.2-0.1-0.20.00.0-0.2-0.9-0.10.01.00.4-0.40.6-0.70.7-0.7-0.3-0.31.3
Progressive ratio test 2 breakpoint0.30.41.8-0.3-0.1-0.1-0.0-0.0-0.1-1.0-0.20.01.10.4-0.40.7-0.80.8-0.8-0.3-0.31.4
Progressive ratio test 2 inactive lever presses0.40.61.71.0-0.9-1.30.80.8-1.30.20.90.9-0.4-0.70.7-0.40.4-0.40.40.70.7-0.0
Incentive Sensitization - Responses0.10.10.30.3-0.5-0.40.60.6-0.4-0.40.40.50.2-0.30.3-0.10.1-0.10.10.10.10.6
Incentive Sensitization - Breakpoint0.10.10.40.1-0.3-0.30.40.4-0.3-0.50.30.40.3-0.20.20.00.0-0.00.0-0.0-0.00.7
Sum of active levers in priming session hrs 5-64.44.15.9-2.01.61.1-1.6-1.61.1-1.7-1.9-1.72.42.3-2.32.4-2.42.4-2.4-2.1-2.32.4
Progressive ratio0.10.20.5-0.70.30.7-0.3-0.30.7-0.1-0.6-0.40.40.7-0.70.3-0.20.2-0.2-0.6-0.60.5
Food seeking constrained by brief footshock6.58.013.02.9-3.6-3.33.63.6-3.33.13.02.8-2.2-2.42.4-2.72.7-2.62.62.32.4-1.4
Seeking ratio, punishment vs. effort2.94.25.82.4-2.3-2.42.32.3-2.41.82.32.0-1.6-2.12.1-1.91.8-1.71.72.02.0-1.5
Retroperitoneal fat weight0.52.24.2-1.71.82.0-1.8-1.82.0-1.3-1.7-1.50.91.3-1.31.1-1.11.1-1.1-1.4-1.40.6
Reaction time number correct0.00.10.2-0.2-0.1-0.10.20.2-0.10.1-0.10.2-0.00.3-0.30.4-0.10.1-0.1-0.2-0.40.5
Reaction time mean minus median0.41.03.51.00.2-0.2-0.2-0.2-0.10.70.60.7-1.1-1.21.2-1.01.1-1.11.11.41.4-1.9
Reaction time mean minus median AUC0.71.83.71.5-0.6-0.80.50.5-0.81.11.21.2-1.3-1.71.7-1.51.5-1.51.51.81.8-1.9
Reaction time num false alarms0.30.40.91.0-0.2-0.80.10.1-0.80.00.70.2-0.2-0.80.8-0.60.5-0.50.51.00.9-0.7
Reaction time num false alarms AUC0.71.12.31.5-0.9-1.50.70.7-1.50.71.20.8-0.5-1.11.1-0.90.9-0.80.81.31.3-0.8
Reaction time trials correct on left0.00.10.2-0.2-0.1-0.10.20.2-0.10.1-0.10.2-0.00.3-0.30.4-0.10.1-0.1-0.2-0.40.5
Reaction time trials on left0.00.10.3-0.3-0.00.00.00.00.00.0-0.20.10.10.4-0.40.5-0.20.2-0.2-0.3-0.50.6
Reaction time mean0.81.23.1-1.11.81.6-1.8-1.81.6-1.1-1.2-1.30.60.6-0.60.6-0.60.6-0.6-0.6-0.5-0.3
Reaction time mean AUC0.81.33.4-1.11.81.7-1.8-1.81.7-1.2-1.2-1.40.70.6-0.60.6-0.60.6-0.6-0.5-0.5-0.3
Median of all reaction times2.13.04.8-1.92.22.2-2.2-2.22.2-1.8-1.9-2.01.41.5-1.51.4-1.41.4-1.4-1.4-1.40.6
Reaction time omissions1.92.73.6-1.61.71.6-1.8-1.81.5-1.6-1.8-1.31.61.7-1.71.8-1.91.8-1.8-1.4-1.31.2
Reaction time false alarm rate0.20.30.70.9-0.1-0.70.00.0-0.7-0.00.60.1-0.0-0.70.7-0.50.4-0.30.30.80.8-0.6
Reaction time premature initiation rate2.02.84.6-1.72.02.0-2.1-2.12.0-1.7-1.8-1.91.31.4-1.41.3-1.51.5-1.5-1.5-1.50.8
Reaction time premature initiations1.42.43.5-1.71.81.8-1.9-1.91.8-1.5-1.7-1.61.21.4-1.41.4-1.41.4-1.4-1.5-1.61.0
Std. dev. reaction times0.20.41.50.10.90.6-1.0-1.00.6-0.1-0.2-0.2-0.4-0.40.4-0.30.3-0.40.40.50.6-1.2
Reaction time trials completed0.00.10.3-0.3-0.00.00.00.00.00.0-0.20.10.10.4-0.40.5-0.20.2-0.2-0.3-0.50.6
Reaction time trials AUC0.00.10.3-0.30.00.10.00.00.1-0.0-0.20.10.10.4-0.40.5-0.30.3-0.3-0.3-0.50.5
Run reversals in cocaine runway, females0.20.20.6-0.30.80.4-0.6-0.60.4-0.3-0.4-0.8-0.00.2-0.20.00.00.0-0.0-0.1-0.1-0.4
Run reversals in cocaine runway, males0.10.10.3-0.30.30.6-0.3-0.30.6-0.3-0.30.00.30.1-0.10.2-0.20.2-0.2-0.10.00.2
Latency to leave start box in cocaine runway0.80.91.20.9-1.0-0.61.11.1-0.61.01.01.1-1.0-1.11.1-1.00.8-0.80.81.11.1-1.1
Latency to leave start box in cocaine runway, F0.20.20.7-0.50.20.4-0.1-0.10.4-0.3-0.40.10.50.5-0.50.7-0.80.8-0.8-0.5-0.50.4
Latency to leave start box in cocaine runway, M3.73.54.52.0-2.1-1.62.12.1-1.61.82.01.5-1.6-2.02.0-2.11.7-1.71.71.91.9-1.6
Std. dev. time between licks in bursts0.30.30.5-0.60.60.7-0.7-0.70.7-0.7-0.6-0.50.50.5-0.50.5-0.50.5-0.5-0.6-0.50.4
Total sessions with >9 infusions0.40.41.10.8-0.9-1.00.90.9-1.00.30.80.50.0-0.50.5-0.70.2-0.20.20.60.70.4
Short access day 1 total inactive lever presses0.81.02.51.1-1.5-1.61.51.5-1.61.11.11.2-0.5-0.60.6-0.50.6-0.60.60.60.70.2
Short access day 10 total inactive lever presses0.61.42.11.4-1.3-1.51.11.1-1.51.21.21.2-1.1-1.11.1-0.91.3-1.31.31.11.1-1.0
Short access day 1 total infusions0.50.72.00.9-1.2-1.41.21.2-1.40.51.00.80.0-0.50.5-0.60.2-0.20.20.50.60.6
Short access day 10 total infusions0.20.21.3-0.4-0.0-0.0-0.0-0.0-0.0-0.2-0.30.00.70.5-0.50.4-0.60.6-0.6-0.5-0.41.1
Short access total infusions0.10.21.10.2-0.5-0.60.50.5-0.6-0.30.20.30.60.1-0.10.0-0.40.4-0.40.00.01.1
Short access day 1 locomotion1.72.13.0-1.51.31.1-1.2-1.21.1-1.1-1.4-1.11.61.5-1.51.6-1.61.6-1.6-1.6-1.51.7
Short access day 10 total locomotion0.71.32.7-1.21.51.6-1.6-1.61.6-1.2-1.3-1.40.90.8-0.80.7-0.70.7-0.7-0.8-0.80.5
Short access total locomotion0.80.91.3-1.00.90.9-1.0-1.00.9-0.6-1.0-0.91.20.9-0.90.9-1.01.0-1.0-0.9-0.91.1
One hour access (0.3 mA shock)0.20.30.90.7-0.7-0.90.60.6-0.90.00.60.50.1-0.40.4-0.2-0.10.1-0.10.50.50.4
Compulsive drug intake0.00.10.3-0.10.20.3-0.1-0.10.30.10.0-0.1-0.6-0.20.2-0.30.2-0.20.2-0.1-0.0-0.5
One hour access (shock baseline)0.20.20.90.3-0.7-0.80.60.6-0.8-0.10.30.40.50.2-0.20.2-0.40.4-0.40.00.01.0
Social response proportion2.73.14.3-2.12.01.9-2.1-2.11.9-1.6-1.9-1.61.21.7-1.71.7-1.71.6-1.6-1.7-1.81.0
Social responses0.40.61.00.7-0.9-0.80.70.7-0.80.90.81.0-1.0-0.80.8-0.60.7-0.70.70.70.5-0.6
Social time0.10.10.2-0.20.1-0.4-0.1-0.1-0.4-0.1-0.2-0.4-0.10.5-0.50.3-0.30.3-0.3-0.2-0.30.3
Soleus weight0.20.72.9-0.6-0.3-0.40.30.3-0.40.2-0.4-0.30.91.0-1.00.9-0.90.9-0.9-1.1-1.11.7
Bone: stiffness5.59.011.43.4-3.0-3.12.92.9-3.13.03.23.1-2.9-3.03.0-2.92.9-2.92.93.13.1-2.6
Tibialis anterior weight7.826.433.45.3-5.6-5.65.85.8-5.65.75.55.7-4.8-4.84.8-4.84.7-4.84.84.74.7-3.4
Time to tail flick, vehicle, before self-admin1.41.53.4-1.51.41.8-1.3-1.31.9-1.1-1.4-1.20.81.1-1.10.9-0.80.8-0.8-1.1-1.10.6
Time to tail flick, vehicle, after self-admin0.10.10.3-0.1-0.10.50.00.00.50.10.10.0-0.3-0.30.3-0.40.3-0.30.30.10.2-0.4
Time to tail flick, test, before self-admin0.50.51.20.5-0.8-0.10.80.8-0.10.50.61.1-0.8-0.80.8-0.70.9-0.90.90.80.7-0.6
Time to tail flick, test, after self-admin1.11.13.40.7-0.3-0.10.30.3-0.11.20.71.0-1.8-1.11.1-1.21.3-1.31.31.01.0-1.6
Delta time to tail flick, vehicle, before/after SA0.60.61.00.9-0.8-1.00.80.8-1.00.60.90.7-0.7-0.70.7-0.70.7-0.70.70.70.7-0.4
Delta time to tail flick, test, before/after SA0.20.20.6-0.40.70.5-0.7-0.70.5-0.2-0.4-0.5-0.20.2-0.20.1-0.10.1-0.1-0.3-0.1-0.4
Tibia length0.10.20.70.1-0.8-0.50.80.8-0.50.20.30.60.30.0-0.00.3-0.40.4-0.4-0.1-0.20.7
Ambulatory time before self-admin3.14.67.92.4-2.8-2.62.82.8-2.62.42.42.5-1.5-1.91.9-1.71.6-1.61.61.81.9-1.0
Ambulatory time after self-admin1.72.03.11.8-1.7-1.81.71.7-1.81.21.61.2-0.9-1.41.4-1.31.1-1.11.11.41.4-0.9
Bone: tissue strength0.20.20.40.5-0.4-0.50.30.3-0.50.40.40.5-0.5-0.30.3-0.30.4-0.40.40.60.6-0.6
Total heroin consumption1.21.42.9-1.00.70.6-0.9-0.90.6-1.0-0.9-0.41.71.1-1.11.6-1.51.5-1.5-1.1-1.11.6
Bone: trabecular number1.01.62.41.3-1.0-1.10.80.8-1.11.31.21.3-1.5-1.21.2-1.31.5-1.51.51.31.3-1.4
Bone: trabecular spacing0.10.10.20.3-0.1-0.20.20.2-0.20.10.30.4-0.3-0.40.4-0.30.2-0.20.20.40.4-0.5
Bone: trabecular thickness0.20.20.5-0.40.60.6-0.6-0.60.6-0.5-0.5-0.70.30.3-0.30.3-0.40.4-0.4-0.4-0.40.1
Bone: trabecular tissue density4.05.97.02.6-2.5-2.52.62.6-2.52.42.72.6-2.3-2.52.5-2.32.2-2.22.22.52.5-1.9
Water consumed over 24 hours1.31.72.31.5-1.3-1.51.21.2-1.51.21.41.3-1.2-1.31.3-1.31.3-1.31.31.21.3-1.0
Number of responses in last shaping day0.80.83.0-0.6-0.4-0.20.40.4-0.3-0.1-0.3-0.21.00.9-0.91.0-1.41.4-1.4-1.0-0.91.7