Hub : Traits

Fe content in liver

Tags: Physiology · Liver

Project: vulpe_liver_2014

1 significantly associated model · 1 unique gene

Significant Loci

# chr p0 p1 # assoc genes # joint models best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 201865024 202832586 1 1 9.5e-08 0.31 1 100 Ccs

p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Number of licking bursts 8.1 1 0 0 0 1 Ccs
Food consumed during 24 hour testing period 18.6 1 0 0 0 1 Ccs
Mean num. licks in bursts 5.1 1 0 0 0 1 Ccs
Water consumed over 24 hours 11.5 1 0 0 0 1 Ccs
Delay discounting water rate 12 sec 2.7 1 0 0 0 1 Ccs
Bone: post-yield work 4.4 1 0 0 0 1 Ccs
Cd content in liver 5.8 1 0 0 0 1 Ccs
Co content in liver 35.2 1 1 100 0 1 Ccs
K content in liver 9.9 1 0 0 0 1 Ccs
Mg content in liver 22.4 1 0 0 0 1 Ccs
Mn content in liver 4.7 1 0 0 0 1 Ccs
Na content in liver 11.5 1 0 0 0 1 Ccs
Se content in liver 35.1 1 1 100 0 1 Ccs
Zn content in liver 37.9 1 1 100 0 1 Ccs

chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.

Associations by panel

tissue modality # hits % hits/tests avg chisq
Adipose alternative polyA 0 0.000 1.1
Adipose alternative TSS 0 0.000 1.2
Adipose gene expression 0 0.000 1.2
Adipose isoform ratio 0 0.000 1.2
Adipose intron excision ratio 0 0.000 1.2
Adipose mRNA stability 0 0.000 1.2
BLA alternative polyA 0 0.000 1.2
BLA alternative TSS 0 0.000 1.1
BLA gene expression 0 0.000 1.2
BLA isoform ratio 0 0.000 1.1
BLA intron excision ratio 0 0.000 1.2
BLA mRNA stability 0 0.000 1.3
Brain alternative polyA 0 0.000 1.3
Brain alternative TSS 0 0.000 1.2
Brain gene expression 0 0.000 1.2
Brain isoform ratio 0 0.000 1.1
Brain intron excision ratio 0 0.000 1.2
Brain mRNA stability 0 0.000 1.2
Eye alternative polyA 0 0.000 1.0
Eye alternative TSS 0 0.000 1.2
Eye gene expression 0 0.000 1.2
Eye isoform ratio 0 0.000 1.1
Eye intron excision ratio 0 0.000 1.1
Eye mRNA stability 0 0.000 1.2
IL alternative polyA 0 0.000 1.2
IL alternative TSS 0 0.000 1.3
IL gene expression 0 0.000 1.2
IL isoform ratio 0 0.000 1.2
IL intron excision ratio 0 0.000 1.2
IL mRNA stability 0 0.000 1.2
LHb alternative polyA 0 0.000 1.0
LHb alternative TSS 0 0.000 1.3
LHb gene expression 0 0.000 1.2
LHb isoform ratio 0 0.000 1.1
LHb intron excision ratio 0 0.000 1.2
LHb mRNA stability 0 0.000 1.3
Liver alternative polyA 0 0.000 1.3
Liver alternative TSS 0 0.000 1.2
Liver gene expression 1 0.014 1.2
Liver isoform ratio 0 0.000 1.2
Liver intron excision ratio 0 0.000 1.2
Liver mRNA stability 0 0.000 1.2
NAcc alternative polyA 0 0.000 1.2
NAcc alternative TSS 0 0.000 1.3
NAcc gene expression 0 0.000 1.2
NAcc isoform ratio 0 0.000 1.2
NAcc intron excision ratio 0 0.000 1.2
NAcc mRNA stability 0 0.000 1.2
OFC alternative polyA 0 0.000 1.2
OFC alternative TSS 0 0.000 1.1
OFC gene expression 0 0.000 1.2
OFC isoform ratio 0 0.000 1.1
OFC intron excision ratio 0 0.000 1.2
OFC mRNA stability 0 0.000 1.3
PL alternative polyA 0 0.000 1.2
PL alternative TSS 0 0.000 1.2
PL gene expression 0 0.000 1.2
PL isoform ratio 0 0.000 1.1
PL intron excision ratio 0 0.000 1.2
PL mRNA stability 0 0.000 1.2

avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.