Hub : Genes

LOC102553524

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA intron excision ratio chr5_117346887_117361949 0.06 0.05 1.5e-03 0.01 0.04 0.04 0.03 5.7e-02 5.0e-03 2.9e-03 8.2e-03
2 Eye gene expression LOC102553524 0.34 0.22 4.7e-03 -0.01 0.09 0.05 0.04 4.9e-01 1.9e-02 6.8e-02 7.2e-02
3 PL intron excision ratio chr5_117346887_117361949 0.09 0.06 2.2e-13 0.1 0.12 0.11 0.12 4.7e-11 4.3e-13 4.8e-12 9.0e-13
4 Brain intron excision ratio chr5_117346887_117361949 0.07 0.05 3.4e-08 0.07 0.08 0.06 0.06 9.1e-07 1.4e-07 2.7e-06 1.1e-06
5 NAcc intron excision ratio chr5_117346887_117353089 0.01 0.01 8.4e-03 0 0 0 0 1.1e-01 4.7e-02 3.3e-01 1.6e-01
6 IC gene expression LOC102553524 0.1 0.07 2.7e-04 0.05 0.06 0.03 0.05 5.2e-03 1.6e-03 2.0e-02 4.6e-03
7 pVTA gene expression LOC102553524 0.05 0.04 1.4e-04 0.03 0.03 0.01 0.03 1.6e-03 1.3e-03 2.0e-02 3.2e-03
8 Brain intron excision ratio chr5_117346887_117353089 0.03 0.02 6.1e-03 0.01 0.01 0 0.01 4.0e-02 3.0e-02 1.0e-01 3.7e-02
9 NAcc gene expression LOC102553524 0.08 0.05 0.0e+00 0.12 0.12 0.11 0.12 2.2e-17 1.1e-17 7.8e-17 4.5e-17
10 OFC gene expression LOC102553524 0.27 0.18 1.2e-04 0.11 0.14 0.13 0.12 1.5e-03 3.2e-04 6.8e-04 1.0e-03
11 IC isoform ratio XR_010066548.1 0.1 0.09 5.0e-03 0.05 0.03 0.03 0.06 4.4e-03 1.5e-02 2.5e-02 1.9e-03
12 IC isoform ratio XR_010066549.1 0.09 0.09 4.8e-03 0.05 0.03 0.03 0.06 4.5e-03 1.6e-02 2.9e-02 2.0e-03
13 PL intron excision ratio chr5_117346887_117353089 0.06 0.06 9.5e-04 0.03 0.02 0.03 0.03 6.4e-04 1.6e-03 4.8e-04 8.4e-04
14 PL gene expression LOC102553524 0.13 0.08 0.0e+00 0.15 0.16 0.14 0.15 2.0e-16 1.4e-16 6.4e-15 2.3e-16
15 Brain gene expression LOC102553524 0.28 0.14 5.6e-17 0.18 0.18 0.17 0.18 8.6e-17 1.1e-16 7.0e-16 9.9e-17
16 pVTA intron excision ratio chr5_117346887_117361949 0.25 0.15 8.4e-10 0.11 0.12 0.11 0.11 2.0e-09 5.4e-10 2.9e-09 3.1e-09
17 Brain intron excision ratio chr5_117358015_117361949 0.04 0.03 2.3e-04 0.05 0.03 0.04 0.04 2.9e-05 5.1e-04 1.4e-04 1.5e-04
18 BLA gene expression LOC102553524 0.2 0.14 5.1e-08 0.13 0.14 0.11 0.13 1.9e-07 1.2e-07 2.6e-06 1.8e-07
19 NAcc intron excision ratio chr5_117346887_117361949 0.08 0.05 8.6e-14 0.09 0.09 0.09 0.09 1.8e-13 1.7e-13 2.2e-13 2.1e-13
20 IL gene expression LOC102553524 0.23 0.19 1.8e-03 0.1 -0 -0.01 0.1 1.8e-03 3.9e-01 8.2e-01 2.8e-03
21 pVTA intron excision ratio chr5_117346887_117353089 0.06 0.05 6.7e-04 0.03 0.04 0.03 0.03 1.3e-03 6.6e-04 1.6e-03 1.4e-03
22 NAcc intron excision ratio chr5_117358015_117361949 0.03 0.02 2.4e-05 0.02 0.02 0.02 0.02 1.1e-04 2.1e-04 2.2e-04 4.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.91.53.21.3-1.31.21.2-1.2-1.2-1.1-1.1-1.0-1.01.8-1.8-1.8-1.0-1.21.3-1.4-0.80.8-1.3-0.8-0.8
Area under the delay curve1.51.82.91.2-1.41.41.4-1.3-1.3-1.3-1.3-1.3-1.31.2-1.2-1.2-1.3-1.31.3-1.6-1.31.3-1.7-1.2-1.3
BMI with tail1.24.15.4-2.32.1-2.0-2.12.02.01.92.01.91.9-2.22.22.31.82.0-2.22.21.8-1.72.31.61.7
BMI without tail1.23.74.5-2.02.0-2.0-2.02.02.02.02.02.01.9-1.81.81.71.91.9-2.02.11.9-1.92.11.91.8
Body weight0.20.71.4-1.20.9-0.9-0.80.80.80.80.80.70.7-1.11.11.20.70.8-0.90.90.6-0.60.80.60.6
Weight adjusted by age0.81.21.6-1.31.0-1.1-1.11.11.11.11.11.21.2-0.70.70.71.21.2-1.10.81.2-1.20.81.31.2
Bone surface1.22.23.2-1.41.5-1.6-1.51.61.51.61.61.61.6-1.11.11.11.61.4-1.41.41.6-1.71.31.61.8
Bone volume0.20.40.8-0.50.5-0.6-0.60.60.60.60.60.70.7-0.10.10.10.70.6-0.50.50.8-0.80.40.80.9
Breakpoint value in progressive ratio session0.91.12.30.6-0.91.01.0-1.1-1.0-1.1-1.1-1.2-1.2-0.00.00.1-1.3-1.01.1-0.8-1.41.4-1.1-1.5-1.5
Number of licking bursts0.00.10.5-0.10.2-0.1-0.10.10.10.00.0-0.0-0.0-0.70.70.7-0.0-0.1-0.10.3-0.20.1-0.1-0.2-0.0
Context. condit. distance diff. score1.92.32.71.5-1.51.61.6-1.6-1.6-1.6-1.6-1.6-1.61.0-1.0-1.2-1.6-1.51.6-1.6-1.71.6-1.6-1.7-1.5
Locomotion velocity, session 10.10.10.50.1-0.20.20.1-0.1-0.1-0.1-0.1-0.0-0.00.7-0.7-0.70.00.10.0-0.60.1-0.1-0.50.20.1
Locomotion distance, session 11.11.41.61.2-1.21.21.2-1.2-1.2-1.2-1.2-1.2-1.21.1-1.1-1.2-1.2-1.11.2-1.2-1.21.1-1.2-1.1-1.2
Locomotion velocity, session 20.20.20.5-0.70.3-0.4-0.40.40.40.50.50.50.50.1-0.1-0.10.50.7-0.50.40.6-0.60.40.70.5
Locomotion distance, session 20.00.00.00.0-0.0-0.0-0.00.0-0.0-0.00.00.00.00.2-0.2-0.10.0-0.00.10.20.0-0.0-0.10.00.0
Locomotion velocity, session 30.10.10.40.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.30.4-0.4-0.4-0.3-0.30.5-0.7-0.20.2-0.7-0.3-0.2
Locomotion distance, session 30.10.10.3-0.20.3-0.3-0.20.20.20.20.20.20.2-0.30.30.30.10.3-0.20.60.2-0.10.30.10.3
Stereotopy head waving bouts, day 30.60.71.70.9-0.70.70.8-0.8-0.8-0.9-0.9-0.9-0.90.0-0.0-0.0-1.0-1.10.8-0.4-1.11.1-0.5-1.1-1.3
Stereotopy head waving duration, day 30.60.71.50.9-0.80.80.9-0.9-0.9-0.9-0.9-0.9-1.00.3-0.3-0.4-1.0-1.10.9-0.5-1.01.0-0.6-1.1-1.2
Locomotion velocity, session 70.70.81.21.1-0.90.90.9-0.9-0.9-0.9-0.9-0.9-0.90.6-0.6-0.6-0.9-0.91.0-0.6-1.01.0-0.8-1.0-0.9
Locomotion distance, session 70.20.20.50.6-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.4-0.5-0.30.6-0.4-0.50.4-0.7-0.5-0.3
Stereotopy head waving bouts, day 71.31.42.3-1.11.3-1.2-1.21.21.21.11.11.11.1-1.51.51.41.01.1-1.21.51.0-1.01.40.91.0
Stereotopy head waving duration, day 70.70.81.2-0.90.9-0.9-0.90.90.90.90.90.90.9-1.01.00.90.80.9-0.91.10.9-0.81.00.80.8
Locomotion velocity, session 80.60.71.11.0-0.90.80.8-0.8-0.8-0.8-0.8-0.8-0.81.0-1.0-0.9-0.8-0.70.9-0.7-0.70.7-1.0-0.7-0.6
Locomotion distance, session 81.01.52.01.1-1.31.31.2-1.2-1.2-1.2-1.2-1.2-1.21.3-1.3-1.3-1.2-1.01.2-1.4-1.21.1-1.4-1.1-1.0
Degree of sensitization distance0.10.10.2-0.30.2-0.3-0.20.20.20.30.20.20.2-0.40.40.50.30.2-0.00.00.2-0.2-0.10.20.1
Degree of sensitization stereotypy1.51.61.9-1.41.3-1.3-1.31.31.31.31.31.31.3-1.11.11.01.21.4-1.31.31.3-1.31.31.21.4
Conditioned locomotion0.30.31.3-0.50.5-0.4-0.40.30.40.30.30.20.2-1.01.01.00.10.3-0.71.10.00.00.8-0.00.1
Cocaine response after cond. corrected0.70.82.1-0.61.0-0.9-0.90.90.90.80.80.80.8-1.21.21.20.70.5-0.81.50.7-0.61.10.60.6
Cocaine response after cond. not corrected0.40.41.0-0.40.7-0.7-0.70.60.60.60.60.60.6-1.01.01.00.50.3-0.51.00.5-0.40.80.40.3
Cocaine response before conditioning0.10.10.60.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.2-0.2-0.40.5-0.8-0.30.3-0.5-0.3-0.5
Saline control response0.30.40.8-0.70.6-0.5-0.60.60.60.60.60.60.6-0.60.60.60.50.7-0.90.50.5-0.50.90.60.6
Bone: connectivity density0.81.22.0-0.91.0-1.1-1.11.21.11.21.21.21.2-0.50.50.51.31.0-0.90.91.4-1.41.01.31.4
Bone: cortical apparent density5.98.08.73.0-3.02.92.9-2.9-2.9-2.9-2.9-2.9-2.92.8-2.8-2.7-2.8-2.82.8-2.9-2.82.8-2.7-2.7-2.7
Bone: cortical area0.20.40.5-0.40.6-0.6-0.60.60.60.60.60.70.6-0.40.40.50.70.5-0.50.70.7-0.70.60.70.7
Bone: cortical porosity0.40.41.1-0.50.7-0.7-0.70.70.70.60.70.70.7-0.40.40.40.60.8-0.71.10.7-0.70.80.70.6
Bone: cortical porosity0.80.91.5-0.90.9-1.0-1.00.91.00.91.01.01.0-0.60.60.70.91.0-1.01.21.0-1.01.10.90.9
Bone: cortical thickness0.20.30.60.8-0.50.50.5-0.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.4-0.5-0.70.7-0.3-0.50.5-0.4-0.5-0.5
Bone: cortical thickness0.00.00.30.6-0.00.00.0-0.0-0.1-0.1-0.1-0.0-0.00.2-0.2-0.2-0.1-0.20.10.50.00.00.1-0.1-0.2
Bone: cortical tissue density5.77.88.52.9-2.92.92.9-2.9-2.9-2.8-2.8-2.8-2.82.7-2.7-2.7-2.8-2.82.7-2.8-2.82.7-2.7-2.7-2.6
Condit. Reinf. active minus inactive responses0.00.00.30.1-0.20.10.2-0.2-0.2-0.2-0.2-0.2-0.20.1-0.1-0.0-0.2-0.20.3-0.5-0.20.2-0.4-0.2-0.3
Condit. Reinf. active-inactive response ratio0.00.00.1-0.0-0.00.10.1-0.1-0.1-0.1-0.1-0.2-0.2-0.30.30.3-0.2-0.10.00.1-0.30.30.1-0.3-0.3
Condit. Reinf. active responses0.00.10.4-0.2-0.0-0.0-0.00.10.00.10.10.10.10.3-0.3-0.30.20.20.1-0.60.2-0.2-0.30.30.1
Condit. Reinf. inactive responses0.20.20.6-0.30.0-0.1-0.20.20.20.30.30.40.40.8-0.8-0.80.40.5-0.1-0.40.6-0.6-0.10.70.6
Incentive salience index mean0.00.00.0-0.0-0.00.00.0-0.0-0.0-0.0-0.0-0.0-0.0-0.00.00.0-0.00.00.1-0.2-0.00.0-0.1-0.1-0.1
Condit. Reinf. lever presses0.00.10.10.2-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.30.2-0.2-0.2-0.3-0.20.2-0.1-0.30.3-0.2-0.3-0.3
Condit. Reinf. active minus inactive responses1.11.52.61.3-1.31.21.2-1.2-1.2-1.1-1.1-1.1-1.11.6-1.6-1.6-1.0-1.11.3-1.5-0.90.9-1.1-0.9-1.0
Condit. Reinf. active-inactive response ratio0.30.41.20.8-0.60.60.5-0.5-0.6-0.5-0.5-0.4-0.41.1-1.1-1.1-0.4-0.60.7-0.9-0.30.3-0.5-0.2-0.4
Condit. Reinf. active responses1.31.82.71.6-1.41.31.3-1.3-1.4-1.3-1.3-1.2-1.31.5-1.5-1.5-1.2-1.31.5-1.6-1.21.2-1.4-1.1-1.2
Condit. Reinf. inactive responses2.43.13.91.9-1.81.81.8-1.8-1.8-1.8-1.8-1.8-1.81.6-1.6-1.6-1.8-1.71.8-1.8-1.81.8-2.0-1.7-1.7
Condit. Reinf. lever presses1.31.82.2-1.11.4-1.4-1.41.41.41.51.41.51.5-1.11.11.21.51.4-1.31.11.5-1.51.21.51.4
Condit. Reinf. lever reinforcers received0.91.22.01.4-1.11.01.1-1.0-1.1-1.0-1.0-0.9-0.91.4-1.4-1.3-0.9-1.01.3-1.4-0.80.8-1.2-0.8-0.9
Conditioned reinforcement - actives0.10.20.60.6-0.40.40.3-0.4-0.3-0.4-0.3-0.3-0.30.7-0.7-0.7-0.4-0.20.1-0.0-0.20.30.1-0.2-0.0
Conditioned reinforcement - inactives0.60.81.20.8-1.11.11.0-1.0-1.0-1.0-1.0-1.0-1.01.1-1.1-1.1-0.9-0.80.6-0.8-0.90.9-0.5-0.8-0.5
Conditioned locomotion0.10.10.2-0.2-0.20.30.2-0.3-0.2-0.3-0.2-0.3-0.30.1-0.10.1-0.40.0-0.30.2-0.40.40.3-0.4-0.4
Patch foraging indifference point 0 sec6.712.415.5-3.53.5-3.5-3.63.53.63.53.63.53.5-3.33.33.33.53.5-3.93.73.4-3.43.93.43.4
Patch foraging indifference point AUC0.40.61.1-0.80.8-0.8-0.80.90.80.90.90.90.9-0.40.40.40.91.0-0.90.20.9-1.00.21.00.8
Delay disc. indifference point, 0s delay2.02.23.81.1-1.51.51.5-1.5-1.5-1.4-1.5-1.5-1.51.4-1.4-1.4-1.4-1.51.5-2.0-1.51.4-1.9-1.4-1.4
Delay disc. indifference point, 16s delay0.10.10.2-0.40.3-0.3-0.30.30.30.30.30.30.3-0.40.40.40.30.3-0.30.10.3-0.3-0.10.30.2
Delay disc. indifference point, 2s delay0.60.71.20.8-0.70.70.8-0.8-0.8-0.8-0.9-0.9-0.90.1-0.1-0.1-0.9-1.11.0-0.7-1.01.0-0.9-1.0-1.0
Delay disc. indifference point, 24s delay0.40.40.90.6-0.60.60.7-0.6-0.6-0.6-0.7-0.7-0.70.3-0.3-0.3-0.6-0.70.7-0.9-0.70.7-0.9-0.7-0.7
Delay disc. indifference point, 4s delay3.43.64.91.7-1.92.02.0-2.0-1.9-2.0-2.0-2.0-2.01.5-1.5-1.5-2.0-1.91.8-2.0-2.02.0-2.2-1.9-1.8
Delay disc. indifference point, 8s delay2.63.03.81.6-1.81.81.8-1.8-1.7-1.7-1.7-1.7-1.71.8-1.8-1.8-1.6-1.61.6-1.9-1.71.6-1.9-1.5-1.7
Indifference point function ln k0.10.10.7-0.10.2-0.1-0.10.00.10.00.0-0.0-0.1-0.80.80.7-0.1-0.1-0.10.6-0.20.20.7-0.20.0
Indifference point function log k0.10.10.7-0.10.2-0.1-0.10.00.10.00.0-0.0-0.1-0.80.80.7-0.1-0.1-0.10.6-0.20.20.7-0.20.0
Patch foraging total patch changes 0 sec5.810.812.8-3.33.3-3.3-3.43.33.43.33.43.33.3-3.03.03.03.33.2-3.63.33.3-3.23.63.33.2
Patch foraging total patch changes 12 sec0.81.01.6-1.21.0-0.9-1.01.01.01.01.01.01.0-0.90.90.91.01.1-1.30.81.0-1.00.91.00.8
Patch foraging total patch changes 18 sec1.62.52.8-1.41.6-1.6-1.61.71.71.71.71.71.7-1.51.51.41.71.6-1.61.41.6-1.71.21.71.6
Patch foraging total patch changes 24 sec0.81.31.5-1.21.2-1.2-1.21.21.21.21.21.21.2-1.01.01.11.21.1-1.21.01.2-1.20.91.20.9
Patch foraging total patch changes 6 sec2.53.85.8-2.01.9-1.9-2.01.92.02.02.02.02.0-1.61.61.62.02.1-2.42.01.9-1.92.02.12.0
Patch foraging time to switch 0 sec2.55.16.42.5-2.32.22.3-2.2-2.3-2.1-2.2-2.1-2.12.5-2.5-2.5-2.0-2.32.5-2.4-1.91.9-2.5-1.9-2.0
Patch foraging water rate 0 sec2.24.78.4-2.22.3-2.1-2.12.12.22.02.11.91.9-2.92.92.91.82.0-2.32.51.7-1.72.01.61.7
Patch foraging water rate 12 sec3.87.913.0-2.73.0-2.9-2.82.82.82.72.72.62.6-3.53.53.52.52.4-2.73.62.3-2.32.82.22.4
Patch foraging water rate 18 sec0.71.03.4-0.91.1-1.0-0.90.90.90.70.80.70.7-1.81.81.80.60.6-0.91.40.4-0.40.80.30.6
Patch foraging water rate 24 sec0.20.31.5-0.50.4-0.3-0.30.20.30.20.20.10.1-1.21.21.20.00.2-0.40.8-0.20.10.3-0.20.1
Patch foraging water rate 6 sec0.71.02.4-1.11.0-0.9-0.90.90.90.80.90.80.8-1.51.51.40.70.9-1.01.30.6-0.60.80.60.7
Seeking ratio, delayed vs. immediate footshock0.30.42.00.30.2-0.10.1-0.1-0.1-0.2-0.3-0.3-0.3-1.41.41.4-0.4-0.70.60.1-0.70.6-0.2-0.8-0.6
Distance traveled before self-admin0.20.31.5-0.70.4-0.3-0.20.20.20.10.10.00.0-1.11.11.2-0.00.10.0-0.1-0.20.2-0.6-0.3-0.3
Distance traveled after self-admin0.10.10.4-0.3-0.30.30.2-0.2-0.2-0.2-0.2-0.2-0.20.6-0.6-0.4-0.20.10.0-0.4-0.20.2-0.2-0.1-0.4
Extensor digitorum longus weight0.62.23.11.7-1.41.51.5-1.5-1.5-1.6-1.6-1.6-1.60.9-0.9-1.0-1.6-1.71.6-1.2-1.71.7-1.6-1.7-1.5
Bone: elastic displacement0.80.91.51.0-1.00.90.9-0.9-0.9-0.8-0.9-0.8-0.81.2-1.2-1.2-0.8-0.91.0-1.1-0.70.7-1.0-0.7-0.8
Bone: elastic work1.62.13.01.6-1.51.51.5-1.4-1.5-1.4-1.4-1.4-1.41.7-1.7-1.7-1.3-1.41.4-1.4-1.31.3-1.3-1.2-1.2
Bone: endosteal estimation1.02.23.0-1.61.5-1.5-1.51.51.51.41.41.41.4-1.71.71.71.41.5-1.51.61.3-1.31.31.31.4
Bone: endosteal perimeter1.32.83.3-1.81.7-1.7-1.71.71.71.71.71.71.7-1.61.61.51.71.8-1.71.71.7-1.71.41.71.7
Epididymis fat weight0.10.20.30.4-0.40.40.4-0.5-0.4-0.5-0.5-0.5-0.50.2-0.2-0.2-0.5-0.50.3-0.5-0.50.5-0.5-0.5-0.4
Delta time in closed arm before/after self-admin0.20.20.4-0.50.5-0.5-0.50.50.50.50.40.40.4-0.60.60.50.40.4-0.40.50.4-0.40.30.40.3
Delta time in open arm before/after self-admin0.90.91.4-0.60.9-1.0-1.01.01.01.01.01.11.1-0.50.50.61.10.8-0.80.81.1-1.21.01.21.2
Diff in mean of infusions in LGA sessions0.10.10.5-0.50.4-0.4-0.40.30.30.30.30.30.3-0.60.60.70.20.3-0.30.40.2-0.20.20.10.0
Delay discount exponential model param1.71.93.0-1.21.4-1.4-1.41.41.41.41.41.41.4-1.21.21.21.31.4-1.41.61.4-1.41.71.31.4
Extinction: sum of active levers before priming0.40.41.00.7-0.50.50.6-0.6-0.6-0.7-0.7-0.7-0.7-0.10.10.1-0.8-0.80.7-0.1-0.80.8-0.4-0.9-1.0
Active lever presses in extinction session 60.30.30.9-0.90.5-0.4-0.40.40.40.30.40.30.3-0.70.70.90.20.6-0.50.60.2-0.20.50.10.2
Bone: final force0.10.20.30.5-0.40.40.4-0.4-0.4-0.4-0.4-0.5-0.50.1-0.1-0.1-0.5-0.50.30.2-0.50.5-0.2-0.5-0.4
Bone: final moment0.10.10.5-0.10.3-0.3-0.20.20.30.20.20.20.2-0.40.40.50.20.2-0.30.70.1-0.10.40.10.3
Food consumed during 24 hour testing period0.20.30.70.3-0.40.50.5-0.5-0.5-0.6-0.6-0.7-0.7-0.30.30.3-0.7-0.60.3-0.1-0.80.9-0.2-0.9-0.8
Glucose1.01.53.4-1.71.0-1.1-1.21.21.21.21.31.31.3-0.20.20.21.31.9-1.60.71.4-1.41.01.51.3
Heart weight1.62.52.81.2-1.71.71.6-1.7-1.6-1.7-1.6-1.6-1.71.5-1.5-1.6-1.6-1.61.4-1.4-1.61.6-1.4-1.6-1.6
Delay discount hyperbolic model param1.61.72.7-1.21.4-1.4-1.41.31.31.31.31.31.3-1.11.11.11.31.3-1.31.51.3-1.31.61.21.3
Intermittent access intake day 1-15 change0.71.32.01.0-1.31.31.2-1.2-1.2-1.1-1.2-1.2-1.11.1-1.1-1.3-1.1-1.11.0-1.4-1.11.1-1.3-0.9-1.0
Intermittent access intake escalation0.91.72.41.2-1.41.41.4-1.4-1.4-1.3-1.3-1.3-1.31.3-1.3-1.4-1.2-1.31.2-1.6-1.31.2-1.5-1.1-1.2
Intermittent access intake escalation 21.31.52.11.0-1.41.31.3-1.3-1.3-1.2-1.2-1.2-1.21.2-1.2-1.4-1.1-1.11.1-1.4-1.11.1-1.1-1.0-1.1
Intermitt. access day 1 inactive lever presses0.10.40.8-0.70.7-0.7-0.70.70.70.70.70.60.7-0.70.70.90.60.7-0.70.30.6-0.60.40.60.7
Intermitt. access day 15 inactive lever presses0.40.81.10.9-0.91.00.9-1.0-0.9-1.0-1.0-1.0-1.00.8-0.8-0.8-1.0-0.90.7-0.6-1.01.0-0.7-1.0-0.8
Intermitt. access escalation Index0.40.61.1-1.00.6-0.6-0.70.70.70.80.80.80.80.1-0.10.10.91.0-0.90.51.0-1.00.61.00.9
Intermittent access day 1 total infusions0.10.10.20.3-0.40.40.3-0.4-0.3-0.4-0.3-0.4-0.40.3-0.3-0.3-0.5-0.0-0.1-0.2-0.40.5-0.0-0.40.1
Intermittent access day 15 total infusions0.50.71.00.8-1.01.00.9-1.0-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.70.5-1.0-0.90.9-0.8-0.8-0.5
Intermittent access terminal intake (last 3 days)0.40.50.80.8-0.80.90.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.8-0.9-0.8-0.50.4-0.6-0.70.8-0.4-0.7-0.4
Intermittent access total infusions0.30.40.50.7-0.70.70.6-0.7-0.6-0.7-0.6-0.7-0.70.6-0.6-0.6-0.7-0.40.3-0.4-0.70.7-0.2-0.6-0.2
Intermittent access day 1 locomotion0.50.61.4-0.90.7-0.7-0.70.70.80.70.70.70.7-0.70.70.80.61.0-1.20.90.6-0.61.10.61.0
Intermittent access day 15 total locomotion0.10.21.0-0.80.2-0.1-0.30.20.30.30.40.30.30.3-0.3-0.30.30.8-1.00.50.4-0.30.80.50.7
Intermittent access total locomotion0.20.20.7-0.60.4-0.4-0.40.40.50.40.50.40.4-0.40.40.30.40.7-0.80.50.4-0.40.80.40.7
Intermittent access standard deviation0.30.61.10.7-0.90.90.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.8-1.0-0.8-0.60.6-1.1-0.80.7-0.7-0.7-0.5
Left kidney weight0.21.01.60.9-0.90.91.0-1.0-1.0-1.0-1.1-1.1-1.10.5-0.5-0.5-1.1-1.31.2-0.9-1.11.1-1.1-1.2-1.2
Right kidney weight0.20.81.60.9-0.70.80.9-0.9-0.9-1.0-1.0-1.0-1.00.1-0.1-0.1-1.1-1.21.1-0.5-1.11.2-0.9-1.3-1.2
Cocaine induced anxiety0.00.00.10.00.1-0.1-0.10.10.10.20.10.20.20.1-0.1-0.20.30.00.00.00.3-0.30.20.30.1
Post-drug Anxiety0.00.00.1-0.00.2-0.2-0.20.20.20.20.10.20.2-0.40.40.40.20.0-0.00.20.1-0.10.20.10.1
Baseline Anxiety0.00.00.1-0.20.2-0.1-0.10.10.10.10.10.10.1-0.30.30.30.00.2-0.30.20.00.00.1-0.00.2
Tail length0.52.03.51.7-1.51.51.4-1.4-1.4-1.4-1.4-1.3-1.31.7-1.7-1.9-1.3-1.31.4-1.2-1.21.2-1.4-1.1-1.2
Length with tail0.31.31.91.2-1.21.21.2-1.2-1.2-1.1-1.2-1.1-1.11.1-1.1-1.2-1.1-1.21.2-1.2-1.11.1-1.4-1.1-1.1
Length without tail0.00.10.30.2-0.20.30.3-0.3-0.3-0.4-0.4-0.4-0.4-0.30.30.2-0.4-0.40.4-0.2-0.50.5-0.5-0.5-0.5
Times rat made contact with spout0.10.10.2-0.30.3-0.2-0.30.20.30.20.20.20.2-0.40.40.40.20.2-0.40.20.2-0.20.40.20.2
Lifetime Intake0.30.40.60.7-0.70.70.7-0.7-0.6-0.7-0.6-0.7-0.70.8-0.8-0.7-0.7-0.30.2-0.4-0.60.7-0.2-0.6-0.2
Liver weight, left1.93.23.91.9-1.81.81.8-1.9-1.8-1.9-1.9-1.9-1.91.5-1.5-1.4-1.9-2.01.7-1.6-1.91.9-1.6-1.9-1.9
Liver weight, right1.83.24.01.6-1.81.81.8-1.8-1.8-1.8-1.8-1.8-1.81.6-1.6-1.4-1.8-1.71.7-1.9-1.81.8-2.0-1.8-2.0
Locomotor activity0.10.10.4-0.40.3-0.3-0.30.30.30.30.30.30.2-0.40.40.40.30.3-0.40.70.3-0.20.50.20.3
Locomotor testing distance1.52.74.1-1.61.7-1.6-1.61.61.61.61.61.51.5-2.02.01.91.51.5-1.62.01.4-1.41.61.31.5
Locomotor testing rearing0.00.00.1-0.1-0.20.20.2-0.2-0.2-0.2-0.2-0.2-0.20.1-0.1-0.0-0.2-0.10.1-0.2-0.20.3-0.1-0.2-0.3
Locomotion in novel chamber1.11.41.9-1.01.1-1.2-1.21.21.21.21.21.31.3-0.60.60.61.31.3-1.21.31.4-1.41.41.41.2
Locomotion in novel chamber post-restriction0.00.00.3-0.50.2-0.1-0.10.10.10.10.10.00.0-0.30.30.60.00.1-0.10.1-0.00.0-0.1-0.1-0.0
Fecal boli incidents, locomotor time 10.00.00.1-0.1-0.10.1-0.0-0.00.00.00.10.10.10.3-0.3-0.30.10.2-0.20.00.1-0.10.10.20.3
Change in fecal boli incidents, locomotor task0.10.10.30.5-0.20.20.2-0.3-0.3-0.3-0.3-0.3-0.30.1-0.1-0.1-0.4-0.40.30.1-0.30.40.1-0.4-0.3
Time >=10cm from walls, locomotor time 10.00.00.10.00.2-0.2-0.20.20.20.20.20.20.2-0.10.10.10.2-0.10.00.20.2-0.20.10.10.1
Bouts of movement, locomotor time 10.20.20.8-0.50.4-0.4-0.50.40.50.40.50.40.4-0.50.50.60.40.4-0.60.60.4-0.40.90.50.4
Total resting periods, locomotor time 10.20.20.8-0.50.4-0.4-0.40.40.40.40.40.40.4-0.40.40.50.40.4-0.60.70.4-0.40.90.50.4
Rest time, locomotor task time 10.20.20.4-0.40.4-0.4-0.40.40.50.50.50.50.5-0.30.30.40.50.3-0.50.50.5-0.50.60.50.5
Distance moved, locomotor task time 10.10.10.30.3-0.20.20.2-0.2-0.3-0.2-0.2-0.2-0.20.2-0.2-0.3-0.2-0.30.6-0.4-0.20.1-0.3-0.2-0.3
Vertical activity count, locomotor time 10.10.20.3-0.40.5-0.5-0.40.50.40.50.40.40.4-0.60.60.50.40.3-0.20.30.4-0.40.30.40.2
Time >=10cm from walls, locomotor time 21.82.74.32.1-1.61.61.7-1.7-1.7-1.7-1.7-1.7-1.71.2-1.2-1.2-1.7-2.01.9-1.0-1.71.8-1.0-1.8-1.9
Bouts of movement, locomotor time 21.11.82.3-1.51.4-1.3-1.31.31.31.31.31.31.3-1.41.41.41.31.2-1.41.41.2-1.21.51.21.2
Total resting periods, locomotor time 21.11.82.4-1.51.4-1.4-1.41.31.41.31.31.31.3-1.41.41.41.31.3-1.51.41.3-1.21.61.21.3
Rest time, locomotor task time 20.40.50.8-0.60.6-0.6-0.70.70.70.70.80.80.8-0.20.20.20.80.8-0.90.50.8-0.80.80.90.9
Distance moved, locomotor task time 21.21.42.51.3-1.21.11.2-1.2-1.2-1.2-1.2-1.2-1.20.9-0.9-1.0-1.2-1.41.6-1.1-1.21.2-1.0-1.2-1.4
Vertical activity count, locomotor time 20.10.20.40.4-0.30.30.4-0.4-0.4-0.4-0.4-0.4-0.40.1-0.1-0.1-0.4-0.50.6-0.1-0.50.5-0.2-0.5-0.6
Light reinforcement 10.30.71.60.7-1.00.90.9-0.9-0.9-0.9-0.8-0.8-0.81.3-1.3-1.2-0.8-0.60.7-0.7-0.70.7-0.9-0.6-0.5
Light reinforcement 20.20.30.60.2-0.60.60.6-0.5-0.5-0.5-0.5-0.5-0.50.8-0.8-0.8-0.5-0.30.4-0.5-0.40.4-0.5-0.3-0.4
Bone: marrow area0.92.02.9-1.61.4-1.4-1.41.41.41.31.41.31.3-1.71.71.61.31.4-1.41.51.2-1.21.21.21.3
Bone: maximum diameter0.81.62.1-1.41.3-1.2-1.21.21.31.21.21.21.2-1.31.31.31.11.3-1.51.41.1-1.11.31.11.2
Bone: maximum force0.00.00.40.10.2-0.1-0.10.10.10.10.10.10.0-0.40.40.40.0-0.0-0.10.6-0.00.00.3-0.00.2
Bone: maximum moment0.40.71.4-0.60.9-0.8-0.80.80.80.80.80.80.7-1.01.01.10.70.7-0.81.20.7-0.70.80.60.9
Mean time between licks in bursts3.79.211.13.0-3.13.13.1-3.1-3.1-3.1-3.1-3.0-3.02.9-2.9-2.9-3.0-3.03.0-3.3-3.02.9-3.2-2.9-2.8
Mean num. licks in bursts0.10.10.2-0.20.1-0.2-0.20.20.20.20.20.30.30.4-0.4-0.40.30.3-0.2-0.10.4-0.40.40.40.3
Cd content in liver1.92.12.4-1.51.5-1.5-1.51.51.51.51.51.41.4-1.41.41.51.51.4-1.51.51.4-1.41.51.41.5
Co content in liver0.10.10.7-0.10.1-0.10.0-0.0-0.0-0.0-0.1-0.1-0.1-0.80.80.8-0.1-0.20.20.1-0.30.20.2-0.3-0.3
Cu content in liver0.60.71.30.8-0.70.80.8-0.8-0.8-0.9-0.8-0.9-0.90.5-0.5-0.3-0.9-0.90.8-0.8-1.00.9-1.1-1.0-0.7
Fe content in liver0.10.10.80.00.3-0.3-0.20.20.20.20.10.10.1-0.90.90.90.1-0.3-0.10.3-0.10.00.2-0.10.1
K content in liver2.42.33.11.8-1.61.51.5-1.5-1.5-1.5-1.5-1.5-1.41.7-1.7-1.6-1.4-1.51.5-1.6-1.41.4-1.6-1.3-1.2
Mg content in liver0.10.10.5-0.10.3-0.4-0.40.40.40.40.40.40.4-0.10.10.20.40.4-0.30.20.5-0.50.00.50.7
Mn content in liver0.00.00.20.2-0.10.10.1-0.0-0.1-0.0-0.1-0.0-0.00.2-0.2-0.30.00.10.3-0.30.0-0.1-0.40.10.0
Na content in liver4.54.85.92.4-2.32.32.2-2.2-2.2-2.2-2.2-2.2-2.12.4-2.4-2.4-2.1-2.22.1-2.1-2.02.0-2.0-1.9-2.0
Rb content in liver0.80.91.21.1-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.01.0-1.0-0.9-0.9-1.01.0-0.8-0.90.9-1.0-0.9-0.7
Se content in liver0.30.41.1-0.30.7-0.7-0.60.60.60.50.50.50.5-1.01.01.00.40.2-0.40.70.4-0.40.30.30.5
Sr content in liver0.90.81.0-0.90.9-0.9-0.90.90.91.00.90.90.9-0.80.80.81.00.9-0.80.60.9-1.00.91.00.7
Zn content in liver1.92.12.6-1.21.5-1.5-1.51.51.51.51.51.51.5-1.31.31.41.41.4-1.61.61.4-1.41.61.41.6
Bone: minimum diameter1.22.22.7-1.31.5-1.6-1.51.61.51.61.51.61.6-1.21.21.21.61.4-1.21.41.6-1.61.31.61.6
Time in familiar zone, hab. session 12.02.03.21.6-1.31.31.4-1.4-1.4-1.5-1.5-1.6-1.60.5-0.5-0.4-1.6-1.71.4-0.5-1.71.7-1.2-1.8-1.7
Time in novel zone, hab. session 15.55.56.6-2.42.4-2.4-2.42.52.42.52.52.52.5-1.91.91.82.52.5-2.21.82.6-2.62.22.62.5
Total zone transitions, hab. session 12.23.14.11.8-1.71.71.8-1.8-1.8-1.8-1.8-1.8-1.81.4-1.4-1.4-1.8-2.01.8-1.5-1.81.8-1.8-1.8-2.0
Total locomotion distance, hab. session 10.20.30.60.5-0.40.50.5-0.5-0.5-0.5-0.5-0.6-0.6-0.10.10.1-0.6-0.70.5-0.0-0.70.7-0.4-0.7-0.8
Locomotion velocity, hab. session 10.30.40.60.5-0.60.60.6-0.6-0.6-0.6-0.7-0.7-0.70.4-0.4-0.4-0.7-0.70.6-0.5-0.70.7-0.8-0.7-0.7
Time in familiar zone, hab. session 20.30.40.60.7-0.50.50.6-0.6-0.6-0.6-0.6-0.7-0.70.2-0.2-0.1-0.7-0.70.6-0.3-0.70.7-0.7-0.8-0.6
Time in novel zone, hab. session 20.70.71.0-0.80.8-0.8-0.90.90.90.90.90.90.9-0.50.50.41.00.8-0.80.71.0-1.01.01.00.7
Total zone transitions, hab. session 25.97.68.12.8-2.82.82.8-2.8-2.8-2.8-2.8-2.8-2.82.5-2.5-2.5-2.8-2.82.7-2.5-2.82.8-2.7-2.8-2.8
Total locomotion distance, hab. session 22.83.74.12.0-1.92.02.0-2.0-2.0-2.0-2.0-2.0-2.01.6-1.6-1.7-2.0-2.01.9-1.5-2.02.0-1.9-2.0-2.0
Locomotion velocity, hab. session 22.53.33.71.8-1.81.91.9-1.9-1.9-1.9-1.9-1.9-1.91.5-1.5-1.6-1.9-1.81.8-1.4-1.91.9-1.8-1.9-1.9
Novel to familiar place preference ratio1.92.02.9-1.61.5-1.4-1.41.41.41.41.41.31.3-1.71.71.61.31.4-1.51.31.2-1.21.61.21.2
Novelty place preference1.31.42.2-1.41.2-1.2-1.21.21.21.21.21.11.1-1.51.51.41.11.2-1.31.01.0-1.01.31.01.0
Time in novel zone, NPP test1.92.03.0-1.61.5-1.4-1.41.41.41.41.41.31.3-1.71.71.61.31.3-1.41.21.2-1.21.51.21.2
Total zone transitions, NPP test1.82.62.91.6-1.71.71.7-1.7-1.7-1.7-1.7-1.7-1.71.5-1.5-1.5-1.7-1.71.5-1.2-1.71.7-1.4-1.7-1.7
Total locomotion distance, NPP test0.20.30.50.5-0.50.50.5-0.6-0.5-0.6-0.6-0.6-0.60.1-0.1-0.1-0.6-0.70.5-0.0-0.70.7-0.2-0.7-0.6
Locomotion velocity, NPP test0.40.60.90.7-0.80.80.8-0.8-0.8-0.9-0.8-0.9-0.90.4-0.4-0.4-0.9-0.90.7-0.3-0.91.0-0.5-1.0-0.9
Intraocular pressure0.30.41.2-0.70.6-0.6-0.50.50.50.50.50.40.4-1.11.11.00.40.5-0.50.90.3-0.30.70.20.2
Delta distance traveled before/after self-admin0.30.31.4-0.0-0.20.1-0.00.00.10.10.20.20.21.2-1.2-1.20.30.4-0.4-0.00.5-0.40.70.60.5
Delta ambulatory time before/after self-admin0.20.31.70.2-0.40.40.2-0.2-0.2-0.1-0.1-0.1-0.11.3-1.3-1.30.00.1-0.1-0.30.2-0.10.40.30.2
Parametrial fat weight6.816.018.0-4.24.1-4.2-4.14.24.14.14.14.14.1-3.73.73.74.14.0-4.03.64.1-4.13.54.04.1
Pavlov. Cond. lever latency0.70.91.80.9-1.00.90.9-0.9-0.9-0.8-0.8-0.8-0.81.3-1.3-1.2-0.7-0.91.0-1.3-0.60.6-0.9-0.6-0.6
Pavlov. Cond. magazine entry latency0.30.40.70.8-0.70.70.6-0.7-0.7-0.7-0.7-0.6-0.70.8-0.8-0.9-0.7-0.60.5-0.2-0.60.6-0.3-0.6-0.7
Pavlov. Cond. change in total contacts0.50.60.8-0.80.8-0.8-0.80.80.80.80.80.80.8-0.60.60.60.80.9-0.80.70.8-0.80.60.80.8
Pavlov. Cond. index score0.10.10.6-0.20.2-0.2-0.30.20.20.20.20.20.2-0.20.20.20.20.3-0.40.80.2-0.10.50.20.1
Pavlov. Cond. latency score0.20.31.2-0.40.5-0.4-0.50.40.50.40.40.40.4-0.60.60.60.30.5-0.61.10.3-0.30.80.30.2
Pavlov. Cond. lever contacts0.20.20.5-0.50.5-0.4-0.40.40.40.40.40.30.3-0.60.60.60.30.5-0.50.70.3-0.30.40.30.2
Pavlov. Cond. magazine entry number0.50.61.2-0.90.9-0.9-0.80.80.80.80.80.80.8-1.01.01.10.80.6-0.50.40.7-0.80.50.70.8
Pavlov. Cond. intertrial magazine entries1.11.33.20.9-1.21.11.1-1.1-1.1-1.0-1.0-1.0-1.01.6-1.6-1.5-0.9-0.91.0-1.8-0.90.8-1.3-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.7-0.30.3-0.3-0.40.30.40.30.30.30.3-0.20.20.20.30.5-0.50.80.3-0.30.60.30.2
Pavlov. Cond. response bias0.10.20.30.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.40.5-0.5-0.6-0.4-0.20.3-0.2-0.40.4-0.4-0.4-0.5
Pavlov. Cond. lever latency1.41.92.31.2-1.51.51.5-1.5-1.4-1.5-1.5-1.5-1.51.2-1.2-1.2-1.5-1.41.2-1.2-1.51.5-1.1-1.5-1.5
Pavlov. Cond. magazine entry latency1.11.41.9-1.01.1-1.2-1.21.21.21.31.21.31.3-0.80.80.91.41.2-1.00.91.3-1.41.01.41.4
Pavlov. Cond. change in total contacts1.01.62.0-1.01.3-1.3-1.31.31.31.41.31.41.4-1.01.01.01.41.3-1.01.01.4-1.41.01.41.4
Pavlov. Cond. index score0.91.21.6-0.81.1-1.2-1.11.21.11.21.11.21.2-0.80.80.81.21.1-0.80.81.2-1.30.81.21.3
Pavlov. Cond. latency score0.81.11.4-0.81.0-1.1-1.11.11.11.11.11.11.1-0.80.80.91.21.0-0.80.91.1-1.20.81.11.2
Pavlov. Cond. lever contacts1.41.92.4-1.11.5-1.5-1.51.51.41.51.51.51.5-1.21.21.21.51.4-1.21.21.5-1.51.11.51.5
Pavlov. Cond. magazine entry number0.30.40.80.4-0.60.60.6-0.6-0.6-0.7-0.6-0.7-0.70.3-0.3-0.3-0.7-0.60.4-0.4-0.80.8-0.4-0.8-0.9
Pavlov. Cond. intertrial magazine entries1.92.95.31.7-1.81.71.7-1.7-1.7-1.6-1.6-1.5-1.52.3-2.3-2.3-1.5-1.61.7-1.9-1.31.4-1.5-1.3-1.5
Pavlov. Cond. lever-magazine prob. diff.1.01.31.8-0.91.1-1.2-1.21.21.21.31.21.31.3-0.90.90.91.31.1-0.90.81.3-1.30.81.31.3
Pavlov. Cond. response bias0.91.21.8-0.81.1-1.2-1.11.21.11.21.21.31.3-0.70.70.71.31.1-0.80.71.3-1.30.81.31.3
Time in closed arm before self-admin0.10.10.3-0.1-0.20.30.3-0.3-0.3-0.3-0.3-0.4-0.4-0.20.20.2-0.4-0.10.1-0.3-0.50.4-0.3-0.5-0.0
Time in closed arm after self-admin0.20.21.6-0.40.4-0.3-0.20.20.30.20.20.10.1-1.21.21.20.10.2-0.20.3-0.10.10.1-0.20.2
Time in open arm before self-admin0.10.10.3-0.2-0.20.20.1-0.1-0.1-0.1-0.1-0.1-0.10.6-0.6-0.6-0.00.0-0.0-0.10.10.0-0.30.1-0.4
Time in open arm after self-admin1.51.62.8-1.21.1-1.2-1.31.31.31.41.41.41.4-0.30.30.31.51.3-1.41.21.6-1.61.41.71.4
Bone: periosteal estimation0.81.72.1-1.41.4-1.4-1.31.31.31.31.31.31.3-1.51.51.51.31.2-1.21.41.2-1.21.21.21.3
Bone: periosteal perimeter0.40.81.1-0.90.8-0.8-0.90.90.90.90.90.90.9-0.60.60.61.01.0-0.90.71.0-1.00.81.01.0
Bone: post-yield work1.92.74.2-1.51.8-1.7-1.71.71.71.61.61.61.5-2.02.02.01.41.4-1.52.01.4-1.41.71.31.5
Progressive ratio test 1 active lever presses0.60.81.70.8-1.01.00.9-1.0-0.9-1.0-0.9-0.9-0.91.3-1.3-1.2-1.0-0.50.4-0.5-0.80.9-0.4-0.8-0.4
Progressive ratio test 1 breakpoint0.91.12.01.0-1.21.21.1-1.1-1.1-1.2-1.0-1.1-1.11.4-1.4-1.3-1.1-0.60.5-0.6-1.01.1-0.5-1.0-0.6
Progressive ratio test 1 inactive lever presses1.31.82.61.3-1.51.51.4-1.5-1.4-1.4-1.4-1.4-1.41.6-1.6-1.6-1.4-1.00.9-1.3-1.31.3-1.1-1.2-0.9
Progressive ratio test 2 active lever presses0.10.10.3-0.3-0.00.1-0.10.00.10.00.10.10.10.3-0.3-0.30.10.4-0.60.30.2-0.10.60.20.5
Progressive ratio test 2 breakpoint0.00.10.2-0.1-0.20.20.1-0.1-0.0-0.1-0.0-0.1-0.10.4-0.4-0.4-0.10.2-0.40.20.00.00.40.10.3
Progressive ratio test 2 inactive lever presses0.10.20.70.1-0.60.60.5-0.5-0.4-0.5-0.4-0.4-0.40.8-0.8-0.8-0.40.0-0.2-0.4-0.30.4-0.0-0.20.0
Incentive Sensitization - Responses0.40.61.2-1.00.6-0.6-0.70.70.70.70.80.70.7-0.50.50.40.80.9-1.10.80.8-0.81.10.90.9
Incentive Sensitization - Breakpoint0.50.71.3-1.10.7-0.7-0.80.70.80.80.80.80.8-0.60.60.50.80.9-1.10.80.8-0.81.11.00.9
Sum of active levers in priming session hrs 5-60.70.61.50.6-0.50.60.7-0.7-0.7-0.8-0.8-0.9-0.9-0.30.30.4-1.0-0.90.8-0.3-1.11.1-0.6-1.2-1.1
Progressive ratio1.01.63.11.3-1.31.31.2-1.2-1.2-1.2-1.1-1.1-1.11.7-1.7-1.7-1.1-1.11.1-1.2-1.01.0-1.4-0.9-1.2
Food seeking constrained by brief footshock4.35.25.72.3-2.32.32.4-2.3-2.3-2.3-2.4-2.4-2.42.1-2.1-1.9-2.3-2.32.4-2.3-2.32.3-2.4-2.3-2.1
Seeking ratio, punishment vs. effort0.20.30.60.4-0.50.50.6-0.6-0.6-0.6-0.6-0.7-0.7-0.10.10.1-0.7-0.60.7-0.6-0.80.7-0.4-0.8-0.4
Retroperitoneal fat weight0.31.11.4-1.01.1-1.1-1.11.11.11.01.11.01.0-1.11.11.11.01.0-1.21.11.0-1.01.00.90.9
Reaction time number correct0.00.10.3-0.30.2-0.2-0.20.10.20.10.10.10.1-0.40.40.50.10.0-0.20.4-0.00.00.4-0.0-0.1
Reaction time mean minus median0.00.10.40.2-0.20.20.2-0.1-0.2-0.1-0.1-0.1-0.10.5-0.5-0.6-0.0-0.10.3-0.50.0-0.0-0.30.0-0.0
Reaction time mean minus median AUC0.10.20.40.4-0.50.40.4-0.4-0.4-0.4-0.4-0.4-0.40.5-0.5-0.7-0.4-0.30.5-0.5-0.30.3-0.5-0.3-0.4
Reaction time num false alarms0.10.20.6-0.2-0.1-0.0-0.10.10.10.20.20.30.30.8-0.8-0.80.30.2-0.3-0.30.5-0.50.20.60.4
Reaction time num false alarms AUC0.30.51.2-0.70.4-0.5-0.60.60.60.70.70.80.80.5-0.5-0.50.80.7-0.70.01.0-1.00.51.11.0
Reaction time trials correct on left0.00.10.3-0.30.2-0.2-0.20.10.20.10.10.10.1-0.40.40.50.10.0-0.20.4-0.00.00.4-0.0-0.1
Reaction time trials on left0.00.10.4-0.40.3-0.2-0.20.20.20.20.20.20.2-0.40.40.60.10.1-0.20.50.1-0.10.40.1-0.0
Reaction time mean0.30.50.6-0.60.7-0.8-0.70.70.70.70.70.80.8-0.60.60.40.80.8-0.40.20.8-0.80.50.70.7
Reaction time mean AUC0.10.10.2-0.30.4-0.4-0.30.40.30.40.30.40.4-0.40.40.20.40.40.0-0.20.4-0.40.20.30.3
Median of all reaction times0.70.91.2-1.01.0-1.1-1.01.01.01.01.01.01.0-1.01.00.81.01.1-0.70.51.0-1.00.91.00.9
Reaction time omissions1.42.03.5-1.91.4-1.4-1.41.41.51.51.51.51.5-0.80.80.81.51.6-1.60.81.6-1.61.31.61.5
Reaction time false alarm rate0.40.61.4-0.60.4-0.5-0.60.70.60.70.80.80.80.5-0.5-0.50.90.8-0.70.11.1-1.10.41.21.1
Reaction time premature initiation rate0.40.51.10.6-0.70.70.7-0.7-0.7-0.7-0.7-0.7-0.70.3-0.3-0.4-0.7-0.80.8-0.9-0.80.7-0.7-0.7-1.1
Reaction time premature initiations0.40.71.60.7-0.80.80.8-0.8-0.8-0.8-0.9-0.9-0.90.3-0.3-0.3-0.9-1.00.9-0.9-1.01.0-0.7-1.0-1.3
Std. dev. reaction times0.40.71.0-0.70.8-0.9-0.90.90.80.90.90.90.9-0.60.60.41.00.9-0.50.41.0-1.00.61.00.9
Reaction time trials completed0.00.10.4-0.40.3-0.2-0.20.20.20.20.20.20.2-0.40.40.60.10.1-0.20.50.1-0.10.40.1-0.0
Reaction time trials AUC0.00.10.3-0.40.3-0.2-0.20.20.20.20.20.10.1-0.40.40.50.10.1-0.20.40.1-0.10.40.0-0.0
Run reversals in cocaine runway, females0.00.00.2-0.3-0.20.20.1-0.1-0.1-0.1-0.0-0.0-0.00.4-0.4-0.5-0.00.2-0.20.10.0-0.00.10.10.0
Run reversals in cocaine runway, males0.20.20.4-0.30.4-0.5-0.50.50.40.50.50.60.60.2-0.20.10.50.5-0.40.40.7-0.60.50.60.6
Latency to leave start box in cocaine runway0.10.10.40.3-0.10.10.2-0.2-0.2-0.2-0.3-0.3-0.3-0.40.40.3-0.3-0.50.40.2-0.40.4-0.2-0.5-0.6
Latency to leave start box in cocaine runway, F0.10.10.4-0.20.4-0.4-0.40.40.40.40.40.40.4-0.40.40.40.40.3-0.20.60.4-0.40.50.30.0
Latency to leave start box in cocaine runway, M0.40.40.90.5-0.50.50.6-0.6-0.6-0.6-0.6-0.7-0.7-0.20.20.0-0.7-0.90.7-0.3-0.80.7-0.6-0.8-0.7
Std. dev. time between licks in bursts0.00.00.2-0.20.0-0.00.00.0-0.00.0-0.0-0.0-0.0-0.20.20.2-0.00.00.0-0.4-0.10.0-0.2-0.0-0.0
Total sessions with >9 infusions1.01.22.10.8-1.21.31.1-1.2-1.1-1.3-1.1-1.2-1.21.4-1.4-1.3-1.3-0.70.6-0.6-1.11.2-0.6-1.1-0.9
Short access day 1 total inactive lever presses0.00.00.1-0.20.0-0.0-0.00.00.10.10.00.00.0-0.40.40.20.10.2-0.2-0.2-0.0-0.0-0.10.10.1
Short access day 10 total inactive lever presses0.71.82.3-1.51.4-1.4-1.41.41.41.41.41.41.4-1.21.21.21.41.2-1.31.31.4-1.41.41.41.2
Short access day 1 total infusions0.10.20.50.4-0.40.40.4-0.4-0.4-0.4-0.3-0.3-0.40.7-0.7-0.7-0.4-0.10.10.0-0.30.3-0.2-0.3-0.1
Short access day 10 total infusions0.30.30.60.6-0.60.70.6-0.7-0.6-0.7-0.6-0.6-0.70.6-0.6-0.6-0.8-0.20.10.0-0.60.70.1-0.7-0.2
Short access total infusions0.20.20.60.5-0.50.50.4-0.5-0.4-0.5-0.4-0.4-0.40.8-0.8-0.7-0.5-0.10.0-0.0-0.40.40.1-0.4-0.0
Short access day 1 locomotion0.10.20.6-0.30.0-0.0-0.20.10.20.10.20.20.20.7-0.7-0.80.20.6-0.60.50.4-0.30.50.40.4
Short access day 10 total locomotion1.01.93.1-1.71.3-1.3-1.41.31.41.31.41.31.3-1.21.21.21.21.6-1.81.51.2-1.21.51.21.5
Short access total locomotion0.10.10.5-0.4-0.00.1-0.1-0.00.1-0.00.10.00.00.4-0.4-0.3-0.10.5-0.70.50.1-0.00.70.10.3
One hour access (0.3 mA shock)0.20.20.80.5-0.50.50.4-0.4-0.4-0.4-0.4-0.3-0.30.9-0.9-0.8-0.3-0.20.2-0.2-0.20.30.1-0.20.1
Compulsive drug intake3.94.65.7-2.12.2-2.3-2.22.32.22.32.32.32.3-1.71.71.92.42.0-1.81.92.3-2.41.92.32.1
One hour access (shock baseline)1.72.63.41.7-1.81.81.7-1.8-1.7-1.8-1.7-1.7-1.71.8-1.8-1.8-1.8-1.41.2-1.3-1.61.7-1.0-1.6-1.1
Social response proportion1.21.42.3-1.51.0-1.1-1.21.21.21.21.21.31.3-0.40.40.51.31.5-1.20.71.4-1.40.91.51.4
Social responses0.30.41.80.2-0.70.60.5-0.5-0.5-0.5-0.4-0.4-0.41.3-1.3-1.3-0.3-0.10.4-0.8-0.20.2-0.6-0.1-0.1
Social time0.30.41.0-0.90.3-0.4-0.40.50.50.50.60.60.60.5-0.5-0.40.71.0-0.7-0.20.8-0.80.20.90.8
Soleus weight0.30.81.71.2-0.80.80.9-0.8-0.9-0.8-0.9-0.8-0.80.7-0.7-0.7-0.8-1.01.2-0.7-0.80.8-1.3-0.8-0.8
Bone: stiffness0.00.10.3-0.20.2-0.1-0.20.10.20.10.10.10.0-0.50.50.50.00.0-0.30.5-0.00.10.4-0.1-0.0
Tibialis anterior weight8.629.131.0-5.65.6-5.6-5.55.55.55.55.55.45.4-5.25.25.35.45.4-5.35.45.3-5.35.25.25.5
Time to tail flick, vehicle, before self-admin1.11.21.8-1.11.1-1.1-1.11.11.11.11.11.11.1-1.21.21.11.01.0-1.01.31.0-1.01.11.01.0
Time to tail flick, vehicle, after self-admin0.91.11.6-1.21.1-1.1-1.11.11.11.11.11.11.1-1.11.11.11.11.1-1.00.91.0-1.11.01.01.0
Time to tail flick, test, before self-admin0.00.00.2-0.00.1-0.1-0.10.10.10.10.10.10.1-0.00.0-0.10.1-0.0-0.2-0.00.2-0.10.20.20.4
Time to tail flick, test, after self-admin0.10.20.30.3-0.40.40.4-0.4-0.4-0.4-0.4-0.5-0.50.1-0.1-0.1-0.4-0.40.3-0.6-0.50.5-0.2-0.5-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.20.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.30.1-0.1-0.1-0.3-0.30.4-0.3-0.40.3-0.2-0.4-0.4
Delta time to tail flick, test, before/after SA0.10.10.2-0.30.3-0.3-0.30.30.30.30.30.30.3-0.20.20.40.30.4-0.30.30.2-0.30.50.20.3
Tibia length2.05.47.42.1-2.32.42.4-2.5-2.4-2.5-2.5-2.6-2.61.6-1.6-1.4-2.6-2.32.1-1.6-2.72.7-1.9-2.7-2.6
Ambulatory time before self-admin0.20.31.7-0.40.2-0.10.0-0.0-0.1-0.1-0.2-0.2-0.2-1.21.21.3-0.3-0.20.4-0.3-0.60.5-0.9-0.6-0.6
Ambulatory time after self-admin0.10.10.3-0.3-0.10.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.00.00.1-0.2-0.00.2-0.5-0.30.2-0.5-0.2-0.4
Bone: tissue strength0.10.10.2-0.20.1-0.1-0.10.20.10.20.20.20.20.2-0.2-0.20.30.3-0.0-0.20.3-0.3-0.10.30.4
Total heroin consumption0.50.61.20.7-0.70.70.8-0.8-0.8-0.8-0.8-0.9-0.90.3-0.3-0.2-0.9-0.90.9-0.7-1.01.0-0.8-1.0-1.1
Bone: trabecular number0.50.92.11.1-1.00.90.9-0.8-0.9-0.8-0.8-0.7-0.71.4-1.4-1.4-0.7-0.91.1-1.0-0.60.6-1.0-0.6-0.6
Bone: trabecular spacing0.10.10.8-0.20.3-0.3-0.20.20.20.20.20.10.1-0.90.90.90.10.0-0.20.3-0.10.00.2-0.10.2
Bone: trabecular thickness0.00.00.1-0.2-0.10.10.0-0.1-0.0-0.1-0.0-0.1-0.00.2-0.2-0.2-0.10.2-0.3-0.0-0.00.00.10.0-0.0
Bone: trabecular tissue density13.319.721.74.5-4.64.74.6-4.6-4.5-4.5-4.5-4.5-4.54.5-4.5-4.5-4.4-4.34.1-4.4-4.44.4-4.1-4.2-4.3
Water consumed over 24 hours0.10.10.8-0.10.3-0.2-0.20.20.20.10.10.00.0-0.90.90.9-0.0-0.1-0.20.4-0.20.20.2-0.2-0.2
Number of responses in last shaping day0.10.10.1-0.1-0.20.30.2-0.3-0.2-0.3-0.2-0.2-0.20.3-0.3-0.3-0.30.2-0.30.1-0.20.30.2-0.20.1