Coq7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Eye	intron excision ratio	chr1_172841200_172851026	0.4	0.16	1.1e-03	0.17	0.1	0.12	0.13	1.2e-03	1.1e-02	7.8e-03	4.8e-03
2	NAcc	mRNA stability	Coq7	0.05	0.03	1.4e-05	0.03	0.03	0.03	0.03	3.4e-04	9.0e-05	5.8e-04	5.7e-04
3	pVTA	gene expression	Coq7	0.2	0.1	5.8e-06	0.09	0.1	0.11	0.11	1.5e-04	4.8e-05	1.8e-05	2.1e-05
4	Brain	isoform ratio	XM_006230108.3	0.05	0.03	1.5e-03	0	0.01	0.01	0	1.5e-01	1.5e-02	5.6e-02	1.6e-01
5	PL	mRNA stability	Coq7	0.03	0.02	5.8e-03	0.01	0.01	0.02	0.01	2.8e-02	1.7e-02	6.3e-03	1.4e-02
6	Brain	mRNA stability	Coq7	0.13	0.07	2.0e-07	0.04	0.03	0.04	0.03	3.3e-04	4.7e-04	1.3e-04	4.2e-04
7	Brain	gene expression	Coq7	0.19	0.09	3.8e-11	0.12	0.1	0.1	0.11	1.5e-11	6.5e-10	1.5e-09	4.1e-10
8	PL	gene expression	Coq7	0.08	0.05	2.7e-05	0.04	0.04	0.03	0.03	1.3e-05	2.7e-05	2.1e-04	1.0e-04
9	Liver	gene expression	Coq7	0.05	0.03	4.8e-04	0	0.01	0.01	0	3.2e-01	1.1e-02	2.9e-02	1.2e-01
10	NAcc	gene expression	Coq7	0.05	0.04	7.2e-04	0.02	0.01	0.02	0.02	1.0e-03	1.4e-02	7.1e-04	1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.6	1.1	2.3	-1.5	-1.2	-1.4	-1.2	1.1	0.7	-1.0	-0.9	-0.1	0.4
Area under the delay curve	0.7	0.8	1.3	0.4	0.8	0.9	0.9	-0.9	-1.1	0.8	0.9	1.1	0.9
BMI with tail	3.5	11.5	15.8	-3.3	-3.6	-4.0	-3.8	3.9	3.6	-3.0	-3.0	-2.7	-2.7
BMI without tail	8.9	18.4	24.9	-4.5	-4.7	-5.0	-5.0	4.8	4.4	-4.1	-3.7	-3.2	-3.1
Body weight	2.2	9.2	14.9	-3.6	-3.5	-3.9	-3.5	3.7	2.9	-2.6	-2.5	-1.7	-1.4
Weight adjusted by age	2.0	2.2	4.1	-0.5	-0.9	-1.1	-1.3	1.4	1.9	-1.5	-1.6	-2.0	-2.0
Bone surface	0.7	1.2	2.3	-1.4	-1.5	-1.2	-1.2	1.2	1.2	-0.8	-0.7	-0.7	0.7
Bone volume	1.1	1.8	3.6	-1.9	-1.8	-1.6	-1.5	1.4	1.3	-1.1	-1.0	-0.5	0.8
Breakpoint value in progressive ratio session	0.9	1.0	3.0	1.4	1.7	1.0	0.8	-1.2	-1.0	-0.3	-0.1	0.8	-0.6
Number of licking bursts	6.5	7.7	11.0	2.7	2.6	3.3	3.3	-2.9	-2.6	3.1	3.1	1.3	2.1
Context. condit. distance diff. score	0.1	0.2	0.5	0.7	0.6	0.3	0.3	-0.1	-0.5	-0.0	0.3	-0.2	-0.4
Locomotion velocity, session 1	0.5	0.6	3.0	0.2	0.1	0.6	0.4	-0.6	-0.7	0.8	0.6	0.6	1.7
Locomotion distance, session 1	0.9	1.1	2.2	-0.8	-1.0	-1.1	-1.3	1.1	1.0	-1.5	-1.4	-0.4	-0.3
Locomotion velocity, session 2	0.7	0.8	2.0	0.5	0.6	1.1	0.9	-1.2	-0.6	0.9	0.5	1.0	1.4
Locomotion distance, session 2	0.9	1.3	2.5	-1.5	-1.6	-1.3	-1.4	1.1	0.9	-1.0	-0.9	-0.4	0.7
Locomotion velocity, session 3	0.2	0.2	0.7	-0.3	-0.5	-0.4	-0.5	0.4	0.3	-0.4	-0.3	-0.2	-0.8
Locomotion distance, session 3	0.3	0.3	1.0	-0.3	-0.8	-0.1	-0.2	0.5	0.1	0.7	1.0	-0.9	0.1
Stereotopy head waving bouts, day 3	0.3	0.3	1.0	0.7	1.0	0.4	0.5	-0.5	-0.5	0.1	-0.1	0.6	-0.4
Stereotopy head waving duration, day 3	0.2	0.3	0.7	0.6	0.8	0.3	0.3	-0.4	-0.1	-0.4	-0.7	0.6	-0.4
Locomotion velocity, session 7	0.9	1.0	2.4	-0.9	-1.6	-0.7	-1.0	1.1	1.5	-0.0	0.1	-1.5	-0.1
Locomotion distance, session 7	0.6	0.7	4.4	-0.0	-0.5	0.4	0.2	-0.0	0.4	1.0	1.0	-0.7	2.1
Stereotopy head waving bouts, day 7	0.3	0.3	0.9	-0.3	-0.2	-0.6	-0.5	0.4	0.2	-1.0	-0.9	0.2	-0.7
Stereotopy head waving duration, day 7	2.0	2.4	3.5	-1.1	-1.4	-1.7	-1.7	1.7	1.5	-1.7	-1.8	-0.9	-1.9
Locomotion velocity, session 8	0.1	0.1	0.3	0.1	0.1	0.2	0.1	-0.2	-0.5	0.1	0.1	0.4	0.4
Locomotion distance, session 8	0.1	0.2	0.4	-0.3	-0.5	-0.4	-0.6	0.6	0.2	-0.5	-0.1	-0.4	0.4
Degree of sensitization distance	0.4	0.4	1.2	0.1	0.7	0.2	0.2	-0.6	-0.2	-0.4	-0.6	1.1	0.9
Degree of sensitization stereotypy	0.9	1.0	1.5	-1.0	-1.2	-1.1	-1.2	1.1	0.7	-1.1	-0.8	-0.5	-0.8
Conditioned locomotion	0.3	0.4	0.8	0.9	0.3	0.6	0.6	-0.3	0.4	0.7	0.8	-0.9	0.0
Cocaine response after cond. corrected	0.4	0.4	0.9	0.6	0.6	0.8	0.7	-0.8	-0.6	0.7	0.4	0.4	0.9
Cocaine response after cond. not corrected	0.1	0.1	0.4	-0.3	-0.3	-0.1	-0.0	0.1	-0.0	0.2	0.2	-0.2	0.6
Cocaine response before conditioning	1.6	2.0	4.0	-2.0	-2.0	-1.7	-1.5	1.9	1.1	-0.6	-0.2	-1.1	-0.6
Saline control response	0.1	0.1	0.8	0.2	0.3	-0.2	-0.1	0.2	-0.0	-0.4	-0.5	0.1	-0.9
Bone: connectivity density	0.6	1.0	1.5	-1.0	-1.1	-1.2	-1.1	1.1	1.0	-1.0	-0.8	-0.8	-0.5
Bone: cortical apparent density	0.9	1.1	1.8	0.7	1.0	1.2	1.2	-1.2	-1.3	1.0	1.0	0.8	1.1
Bone: cortical area	2.0	3.0	6.3	-2.5	-2.4	-2.1	-2.0	1.9	1.7	-1.3	-1.1	-0.6	0.6
Bone: cortical porosity	1.5	1.7	2.2	-1.0	-1.1	-1.4	-1.5	1.5	1.4	-1.3	-1.2	-1.1	-1.4
Bone: cortical porosity	1.1	1.2	2.2	-0.5	-0.6	-1.1	-1.2	1.2	1.1	-1.2	-1.1	-1.0	-1.5
Bone: cortical thickness	0.7	1.1	3.2	-1.7	-1.3	-1.0	-0.9	0.7	0.4	-0.4	-0.4	0.7	1.8
Bone: cortical thickness	1.1	1.3	4.5	-0.8	0.1	0.2	0.5	-0.6	-1.3	0.7	0.9	2.0	2.1
Bone: cortical tissue density	0.9	1.1	1.8	0.7	1.0	1.2	1.2	-1.2	-1.3	1.0	1.0	0.8	1.1
Condit. Reinf. active minus inactive responses	0.1	0.1	0.6	0.1	0.3	-0.3	-0.1	0.3	0.0	-0.1	-0.4	-0.2	-0.7
Condit. Reinf. active-inactive response ratio	0.5	0.5	1.5	-0.3	-0.1	-0.8	-0.6	0.9	0.7	-0.3	-0.8	-0.9	-1.2
Condit. Reinf. active responses	0.0	0.0	0.1	0.3	0.4	-0.0	0.0	0.1	-0.1	-0.1	-0.2	0.1	-0.2
Condit. Reinf. inactive responses	0.1	0.1	0.4	0.4	0.2	0.3	0.2	-0.3	-0.3	-0.1	0.2	0.5	0.6
Incentive salience index mean	0.3	0.3	0.9	-0.4	-0.4	-0.5	-0.4	0.7	0.7	0.0	-0.2	-0.9	-0.9
Condit. Reinf. lever presses	0.3	0.4	1.8	0.1	-0.3	0.0	-0.1	0.4	0.9	0.4	0.2	-1.3	-0.7
Condit. Reinf. active minus inactive responses	1.7	2.1	5.1	-0.6	-0.5	-1.4	-1.5	1.3	1.1	-2.0	-2.0	-0.5	-2.3
Condit. Reinf. active-inactive response ratio	1.1	1.1	4.9	-0.1	0.1	-0.9	-0.8	0.6	0.4	-1.4	-1.5	-0.1	-2.2
Condit. Reinf. active responses	1.3	1.7	4.9	-0.6	-0.7	-1.2	-1.3	1.3	1.1	-1.6	-1.6	-0.7	-2.2
Condit. Reinf. inactive responses	0.6	0.8	1.7	-0.9	-1.3	-0.8	-0.9	1.2	1.1	-0.3	-0.2	-1.0	-0.4
Condit. Reinf. lever presses	2.2	2.9	5.0	-1.2	-1.4	-2.0	-1.9	2.2	1.6	-1.8	-1.8	-1.1	-1.7
Condit. Reinf. lever reinforcers received	1.0	1.4	4.4	-0.3	-0.4	-1.0	-1.1	1.2	1.0	-1.5	-1.5	-0.7	-2.1
Conditioned reinforcement - actives	0.5	0.5	2.9	-0.3	0.2	-0.0	0.1	-0.3	-0.7	-0.6	-0.2	1.7	1.1
Conditioned reinforcement - inactives	1.1	1.3	3.1	0.7	1.0	1.1	1.2	-1.3	-1.2	0.2	0.3	1.8	1.5
Conditioned locomotion	0.2	0.2	0.4	0.4	0.5	0.5	0.5	-0.5	-0.3	-0.1	-0.0	0.6	0.3
Patch foraging indifference point 0 sec	0.8	1.2	3.2	-0.7	-0.3	-1.3	-1.2	1.2	0.2	-1.7	-1.8	0.5	-1.0
Patch foraging indifference point AUC	0.3	0.4	1.0	-1.0	-0.8	-0.8	-0.7	0.6	0.2	-0.4	-0.5	0.4	-0.1
Delay disc. indifference point, 0s delay	0.7	0.7	3.0	-0.9	-0.7	0.2	0.3	-0.2	-0.5	1.0	1.2	0.6	1.7
Delay disc. indifference point, 16s delay	4.6	4.7	7.9	2.4	2.8	2.3	2.4	-2.5	-2.6	1.4	1.5	2.0	0.8
Delay disc. indifference point, 2s delay	1.9	2.2	5.7	-2.4	-2.3	-1.7	-1.6	1.6	1.3	-0.6	-0.5	-0.5	0.4
Delay disc. indifference point, 24s delay	4.1	4.0	5.9	2.2	2.3	2.4	2.3	-2.2	-2.2	1.7	1.8	1.3	1.0
Delay disc. indifference point, 4s delay	1.0	1.0	3.0	-0.2	0.4	0.6	0.7	-0.8	-1.3	0.8	1.0	1.7	1.5
Delay disc. indifference point, 8s delay	0.5	0.5	1.1	0.0	0.3	0.6	0.7	-0.6	-0.4	0.7	0.9	0.9	1.0
Indifference point function ln k	0.1	0.2	0.3	-0.5	-0.5	-0.4	-0.6	0.4	0.5	-0.4	-0.3	-0.1	0.3
Indifference point function log k	0.1	0.2	0.3	-0.5	-0.5	-0.4	-0.6	0.4	0.5	-0.4	-0.3	-0.1	0.3
Patch foraging total patch changes 0 sec	1.0	1.6	4.0	-0.7	-0.3	-1.5	-1.3	1.3	0.4	-2.0	-2.0	0.4	-1.2
Patch foraging total patch changes 12 sec	0.5	0.6	1.2	-0.2	-0.5	-1.0	-0.8	1.1	0.5	-0.7	-0.8	-0.5	-1.1
Patch foraging total patch changes 18 sec	0.1	0.2	0.8	0.3	0.4	0.2	0.2	-0.2	-0.6	-0.1	-0.4	0.9	0.1
Patch foraging total patch changes 24 sec	0.8	1.0	1.8	-0.9	-0.5	-1.3	-1.1	1.2	0.3	-1.4	-1.2	0.4	-0.9
Patch foraging total patch changes 6 sec	0.8	1.2	5.0	0.3	1.2	-0.1	0.2	-0.4	-1.7	-0.9	-1.0	2.2	-0.6
Patch foraging time to switch 0 sec	1.3	2.0	4.3	2.1	1.2	1.8	1.5	-1.1	-0.5	1.6	1.6	-1.2	-0.2
Patch foraging water rate 0 sec	0.2	0.4	0.7	-0.7	-0.6	-0.8	-0.7	0.7	0.4	-0.7	-0.6	-0.1	0.6
Patch foraging water rate 12 sec	1.1	1.7	3.3	-1.5	-0.9	-1.8	-1.5	1.2	0.7	-1.7	-1.8	0.7	-0.4
Patch foraging water rate 18 sec	0.5	0.6	1.6	-0.6	-0.3	-1.0	-0.9	0.6	0.5	-1.3	-1.3	0.1	-0.2
Patch foraging water rate 24 sec	0.3	0.4	1.5	-1.2	-0.6	-0.6	-0.4	0.2	0.5	-0.3	-0.4	0.8	0.6
Patch foraging water rate 6 sec	0.3	0.4	2.3	-0.3	0.3	0.0	0.2	-0.4	-0.5	-0.1	-0.5	1.5	0.7
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.3	-0.0	0.1	0.2	-0.0	-0.2	0.5	-0.5	-0.5	0.2	-0.1
Distance traveled before self-admin	0.4	0.4	1.2	-0.1	0.2	0.6	0.5	-0.6	-0.3	0.3	0.5	1.1	1.0
Distance traveled after self-admin	0.7	0.8	2.3	-1.5	-1.5	-0.5	-0.7	0.6	0.8	-0.0	0.0	0.0	1.1
Extensor digitorum longus weight	2.4	9.5	23.0	-4.8	-4.7	-3.3	-3.2	3.4	3.3	-1.1	-0.9	-2.1	0.0
Bone: elastic displacement	0.8	0.9	2.1	0.7	1.2	0.8	0.9	-1.1	-1.3	0.4	0.3	1.5	0.8
Bone: elastic work	0.1	0.2	0.5	-0.7	-0.4	-0.3	-0.3	0.2	0.1	-0.2	-0.1	0.5	0.7
Bone: endosteal estimation	1.9	4.0	6.0	-2.2	-2.4	-2.1	-2.1	2.3	2.4	-1.4	-1.4	-2.0	-1.2
Bone: endosteal perimeter	0.8	1.7	3.5	-1.3	-1.9	-1.1	-1.2	1.5	1.7	-0.4	-0.2	-1.8	0.1
Epididymis fat weight	1.2	2.9	4.2	-1.5	-1.3	-2.0	-1.9	1.7	1.6	-2.0	-1.9	-0.8	-1.9
Delta time in closed arm before/after self-admin	0.4	0.4	1.4	0.4	-0.1	0.4	0.2	0.0	0.0	0.7	1.1	-1.2	-0.2
Delta time in open arm before/after self-admin	1.9	1.9	3.6	-1.9	-1.5	-1.9	-1.6	1.5	0.9	-1.2	-1.3	-0.0	-0.5
Diff in mean of infusions in LGA sessions	0.5	0.5	1.3	0.7	1.2	0.3	0.4	-0.7	-0.7	-0.7	-0.8	1.0	-0.4
Delay discount exponential model param	0.7	0.7	1.0	-0.5	-0.7	-0.9	-0.9	0.9	1.0	-0.7	-0.9	-1.0	-0.7
Extinction: sum of active levers before priming	0.4	0.4	0.6	0.5	0.5	0.8	0.7	-0.6	-0.8	0.7	0.7	0.2	0.3
Active lever presses in extinction session 6	0.2	0.2	0.8	0.2	0.5	-0.1	-0.1	0.0	-0.1	-0.7	-0.6	0.3	-0.9
Bone: final force	3.8	6.1	11.3	-3.4	-3.3	-2.9	-2.9	2.8	2.6	-2.0	-1.8	-1.1	-0.1
Bone: final moment	3.3	5.4	9.5	-3.1	-3.0	-2.7	-2.7	2.6	2.4	-2.1	-1.8	-1.0	-0.3
Food consumed during 24 hour testing period	0.9	1.0	2.4	-1.5	-1.5	-1.1	-1.1	1.0	1.1	-0.5	-0.7	-0.4	0.2
Glucose	0.2	0.3	1.7	0.2	0.5	0.1	0.2	-0.6	-0.7	-0.2	-0.2	1.3	-0.6
Heart weight	0.3	0.4	1.7	0.2	0.5	0.3	0.3	-0.6	-0.6	-0.2	-0.1	1.3	1.0
Delay discount hyperbolic model param	0.5	0.5	0.9	-0.1	-0.4	-0.6	-0.7	0.7	0.9	-0.6	-0.9	-1.0	-0.8
Intermittent access intake day 1-15 change	1.9	1.8	4.3	0.9	0.8	1.5	1.6	-1.2	-0.8	1.9	1.2	0.7	2.1
Intermittent access intake escalation	1.6	1.5	4.1	0.8	0.7	1.4	1.5	-1.1	-0.7	1.7	1.0	0.7	2.0
Intermittent access intake escalation 2	2.0	2.0	4.2	1.0	0.8	1.5	1.6	-1.2	-1.0	2.1	1.6	0.6	2.0
Intermitt. access day 1 inactive lever presses	0.4	0.5	1.5	0.2	0.4	0.6	0.7	-0.6	-0.5	0.5	0.3	1.0	1.2
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.7	-0.7	-0.9	-0.4	-0.3	0.5	0.5	0.1	-0.1	-0.2	0.5
Intermitt. access escalation Index	0.8	0.7	1.1	-0.8	-0.9	-0.8	-0.9	0.8	1.0	-0.6	-1.0	-0.7	-0.5
Intermittent access day 1 total infusions	1.8	2.1	5.0	-1.0	-0.8	-1.6	-1.6	1.3	0.9	-2.2	-2.0	-0.2	-1.6
Intermittent access day 15 total infusions	0.1	0.1	0.7	-0.1	0.0	-0.3	-0.1	0.2	0.0	-0.6	-0.8	0.5	0.1
Intermittent access terminal intake (last 3 days)	0.2	0.2	0.8	-0.1	-0.0	-0.6	-0.2	0.4	0.1	-0.7	-0.9	0.4	-0.2
Intermittent access total infusions	1.0	1.2	3.1	-0.7	-0.6	-1.2	-1.1	0.9	0.8	-1.8	-1.6	0.2	-0.8
Intermittent access day 1 locomotion	2.1	2.2	5.7	-1.0	-0.7	-1.5	-1.5	1.2	0.9	-2.4	-2.2	-0.1	-1.6
Intermittent access day 15 total locomotion	1.0	1.1	3.0	1.1	1.6	0.5	0.8	-0.8	-1.3	-0.6	-0.7	1.7	-0.3
Intermittent access total locomotion	1.5	1.7	4.7	-0.5	-0.1	-1.3	-1.2	0.9	0.5	-2.2	-2.2	0.2	-1.8
Intermittent access standard deviation	0.2	0.3	1.8	-0.2	-0.2	0.3	0.3	-0.2	-0.1	0.4	0.1	0.5	1.4
Left kidney weight	2.6	7.3	14.6	-3.8	-3.3	-3.4	-3.0	3.2	2.7	-2.1	-1.9	-1.0	-1.1
Right kidney weight	2.9	8.1	16.8	-4.1	-3.5	-3.6	-3.2	3.3	2.6	-2.2	-1.8	-1.1	-1.4
Cocaine induced anxiety	0.1	0.1	0.1	0.4	0.2	0.2	0.1	-0.1	0.3	-0.2	-0.2	-0.3	-0.3
Post-drug Anxiety	0.4	0.4	1.4	0.4	0.8	0.4	0.5	-0.8	-0.6	-0.0	-0.2	1.2	0.5
Baseline Anxiety	0.4	0.4	2.1	-0.7	-0.2	-0.1	-0.1	-0.3	-0.5	0.0	-0.1	1.4	1.1
Tail length	1.6	4.9	9.4	-3.1	-2.7	-2.8	-2.7	2.4	1.9	-2.2	-1.7	-0.6	-0.5
Length with tail	0.2	0.8	2.1	-1.5	-1.1	-1.2	-0.9	1.0	0.4	-0.5	-0.6	0.4	0.6
Length without tail	1.2	2.5	3.5	1.4	1.4	1.5	1.8	-1.5	-1.6	1.9	1.5	1.4	1.8
Times rat made contact with spout	0.6	0.7	2.4	-1.2	-1.5	-0.4	-0.5	0.6	1.1	0.6	0.4	-0.6	0.4
Lifetime Intake	1.8	2.0	4.7	-1.1	-1.0	-1.7	-1.5	1.3	1.1	-2.2	-2.0	0.0	-1.0
Liver weight, left	0.5	0.8	1.6	-0.3	-0.6	-1.0	-1.0	0.9	1.0	-0.9	-0.8	-0.9	-1.3
Liver weight, right	1.8	3.0	7.6	-0.7	-1.4	-1.4	-1.5	1.8	2.0	-1.1	-1.2	-2.4	-2.8
Locomotor activity	0.4	0.6	1.9	-0.2	-0.3	-0.9	-0.7	1.1	0.4	-0.7	-0.6	-0.7	-1.4
Locomotor testing distance	0.5	0.8	1.5	-0.7	-0.6	-1.2	-1.1	1.1	0.4	-1.1	-0.9	-0.4	-1.1
Locomotor testing rearing	0.7	1.0	4.7	0.1	-0.1	-0.9	-0.8	0.9	0.5	-1.1	-1.1	-0.7	-2.2
Locomotion in novel chamber	1.9	2.4	5.3	-0.8	-0.9	-1.3	-1.6	1.3	1.4	-2.3	-2.1	-0.8	-1.9
Locomotion in novel chamber post-restriction	0.5	0.6	2.1	0.4	0.6	-0.4	-0.4	0.1	-0.2	-1.2	-1.5	0.4	-1.1
Fecal boli incidents, locomotor time 1	0.5	0.6	2.2	1.0	0.3	0.2	-0.1	0.2	0.8	-0.4	-0.3	-1.5	-1.1
Change in fecal boli incidents, locomotor task	0.8	0.8	4.1	-0.6	0.3	-0.3	-0.3	-0.3	-0.6	-1.2	-0.9	2.0	0.6
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.6	-0.6	-0.8	-0.3	-0.4	0.2	0.6	-0.3	-0.4	0.0	0.7
Bouts of movement, locomotor time 1	1.7	1.9	4.8	2.2	1.9	1.8	1.5	-1.5	-1.2	0.9	0.8	0.1	-0.3
Total resting periods, locomotor time 1	2.1	2.3	5.5	2.4	2.0	1.9	1.7	-1.5	-1.4	1.2	1.1	0.1	-0.3
Rest time, locomotor task time 1	2.0	2.2	3.5	1.4	1.1	1.8	1.7	-1.4	-1.5	1.6	1.9	0.6	1.3
Distance moved, locomotor task time 1	2.4	2.6	4.7	-1.8	-1.4	-2.2	-1.9	1.7	1.2	-1.6	-1.9	-0.3	-1.4
Vertical activity count, locomotor time 1	1.7	1.8	5.4	-2.3	-1.6	-1.7	-1.4	1.0	1.0	-1.0	-1.3	0.4	-0.0
Time >=10cm from walls, locomotor time 2	1.0	1.1	2.8	-1.7	-1.7	-1.2	-1.1	1.0	0.9	-0.4	-0.1	-0.3	0.8
Bouts of movement, locomotor time 2	1.9	2.0	7.0	-0.2	-1.1	-0.9	-1.1	1.4	1.6	-0.9	-0.9	-2.6	-2.1
Total resting periods, locomotor time 2	2.1	2.2	6.7	-0.4	-1.2	-1.0	-1.3	1.6	1.7	-1.0	-1.0	-2.6	-2.1
Rest time, locomotor task time 2	0.1	0.1	0.3	0.1	0.2	0.2	0.1	-0.2	-0.1	-0.4	-0.3	0.6	0.0
Distance moved, locomotor task time 2	0.3	0.4	1.1	-1.1	-0.8	-0.2	-0.0	0.2	0.1	0.8	0.7	0.1	0.9
Vertical activity count, locomotor time 2	0.4	0.5	1.5	-1.2	-0.5	-0.1	0.1	-0.3	-0.4	0.3	0.2	1.2	1.2
Light reinforcement 1	0.4	0.7	3.5	0.9	0.6	0.2	-0.3	-0.3	0.3	-1.1	-1.1	-0.1	-1.9
Light reinforcement 2	0.5	0.6	1.9	0.1	0.1	-0.5	-0.6	0.1	0.6	-1.3	-1.4	-0.2	-1.2
Bone: marrow area	1.7	3.6	5.4	-2.1	-2.3	-2.0	-2.0	2.2	2.3	-1.3	-1.3	-2.0	-1.1
Bone: maximum diameter	1.8	3.3	5.3	-2.2	-2.3	-2.0	-2.0	2.0	2.1	-1.5	-1.5	-1.2	-0.6
Bone: maximum force	2.8	4.8	9.8	-3.1	-3.0	-2.5	-2.5	2.6	2.1	-1.6	-1.3	-0.9	0.2
Bone: maximum moment	2.4	4.1	8.1	-2.8	-2.7	-2.4	-2.4	2.3	2.0	-1.7	-1.4	-0.7	-0.0
Mean time between licks in bursts	0.1	0.2	1.2	0.6	-0.1	0.2	-0.0	0.3	0.6	0.0	-0.1	-1.1	-0.2
Mean num. licks in bursts	5.8	7.0	10.1	-3.2	-3.1	-3.1	-3.1	2.8	2.8	-2.4	-2.4	-1.2	-1.5
Cd content in liver	2.7	2.9	7.3	2.1	2.7	1.6	1.7	-1.8	-2.1	0.3	0.4	1.5	-1.5
Co content in liver	1.0	1.2	3.7	0.5	1.2	0.7	0.8	-1.2	-1.6	0.2	0.5	1.9	1.0
Cu content in liver	0.3	0.3	0.7	-0.6	-0.2	-0.6	-0.6	0.4	-0.4	-0.8	-0.6	0.8	-0.6
Fe content in liver	1.8	2.1	3.4	1.0	1.4	1.5	1.5	-1.8	-1.5	1.2	0.9	1.8	1.6
K content in liver	0.3	0.3	0.6	-0.3	-0.3	-0.5	-0.5	0.5	0.5	-0.5	-0.6	-0.5	-0.7
Mg content in liver	0.9	0.9	2.2	0.3	-0.1	-0.5	-0.7	0.7	1.1	-0.9	-1.3	-1.5	-1.3
Mn content in liver	0.3	0.3	0.8	-0.6	-0.7	-0.3	-0.4	0.6	0.8	0.1	0.2	-0.9	-0.2
Na content in liver	3.6	3.8	8.0	-2.1	-2.8	-1.8	-2.0	2.1	2.7	-0.5	-0.8	-2.3	-0.5
Rb content in liver	0.9	1.2	2.2	1.1	1.4	0.2	0.2	-0.8	-0.9	-1.3	-1.1	1.4	-1.5
Se content in liver	0.1	0.1	0.6	-0.1	-0.4	0.2	0.1	-0.1	0.3	0.6	0.2	-0.2	0.8
Sr content in liver	0.9	0.9	2.6	-1.1	-1.0	-0.9	-0.9	0.8	0.7	-0.5	-0.4	-0.7	-1.6
Zn content in liver	3.3	3.6	4.9	-1.7	-2.2	-2.1	-2.2	2.1	2.0	-1.6	-1.9	-1.8	-1.1
Bone: minimum diameter	1.4	2.7	5.1	-2.0	-2.3	-1.8	-1.9	1.9	1.9	-1.0	-0.8	-1.5	-0.1
Time in familiar zone, hab. session 1	1.0	0.9	2.9	0.5	1.1	0.7	1.0	-1.0	-1.4	0.3	0.2	1.7	0.4
Time in novel zone, hab. session 1	0.9	0.9	2.8	-0.5	-1.1	-0.8	-1.0	1.1	1.0	-0.2	0.0	-1.7	-0.6
Total zone transitions, hab. session 1	1.2	1.6	3.7	-1.9	-1.6	-1.6	-1.6	1.2	0.6	-1.3	-1.1	0.4	0.3
Total locomotion distance, hab. session 1	3.8	5.3	10.3	-3.2	-2.6	-2.8	-2.9	2.3	1.5	-2.6	-2.4	-0.0	-0.8
Locomotion velocity, hab. session 1	3.8	5.3	8.1	-2.8	-2.3	-2.7	-2.8	2.2	1.7	-2.8	-2.7	-0.2	-1.1
Time in familiar zone, hab. session 2	0.2	0.2	0.3	-0.6	-0.5	-0.5	-0.4	0.4	0.4	-0.4	-0.5	0.2	0.2
Time in novel zone, hab. session 2	0.1	0.1	0.6	0.2	0.2	-0.1	-0.1	0.0	-0.1	-0.2	-0.2	-0.2	-0.8
Total zone transitions, hab. session 2	1.6	2.0	3.5	-1.8	-1.5	-1.9	-1.8	1.6	0.8	-1.6	-1.4	0.0	-0.5
Total locomotion distance, hab. session 2	1.8	2.4	5.6	-2.4	-1.8	-1.9	-1.9	1.4	0.8	-1.6	-1.5	0.3	-0.3
Locomotion velocity, hab. session 2	2.2	3.0	6.6	-2.6	-2.1	-2.2	-2.1	1.7	1.1	-1.7	-1.7	0.0	-0.4
Novel to familiar place preference ratio	1.1	1.2	1.9	0.8	1.0	0.9	1.1	-1.0	-1.4	1.1	1.1	1.0	1.4
Novelty place preference	1.7	1.7	2.9	0.9	1.1	1.2	1.3	-1.3	-1.5	1.3	1.3	1.2	1.7
Time in novel zone, NPP test	1.2	1.3	2.2	0.8	1.1	1.0	1.1	-1.1	-1.4	1.0	0.9	1.1	1.5
Total zone transitions, NPP test	0.9	1.3	2.5	-1.6	-1.4	-1.3	-1.4	1.0	0.8	-1.3	-1.1	-0.0	-0.1
Total locomotion distance, NPP test	0.9	1.2	3.2	-1.8	-1.4	-1.1	-1.2	0.7	0.6	-1.1	-1.1	0.4	0.7
Locomotion velocity, NPP test	0.6	0.9	2.7	-1.6	-1.2	-0.9	-1.0	0.5	0.6	-0.9	-0.8	0.5	0.7
Intraocular pressure	0.3	0.5	0.7	-0.6	-0.7	-0.7	-0.8	0.8	0.8	-0.3	-0.4	-0.8	0.7
Delta distance traveled before/after self-admin	1.3	1.4	2.3	-1.3	-1.5	-1.3	-1.4	1.3	1.3	-0.7	-0.9	-1.2	-0.4
Delta ambulatory time before/after self-admin	0.8	0.9	1.8	-1.3	-1.4	-1.0	-1.1	1.0	1.0	-0.4	-0.7	-0.8	-0.0
Parametrial fat weight	2.2	4.4	7.2	-2.6	-2.0	-2.7	-2.4	2.2	1.7	-2.3	-2.0	-0.3	-1.6
Pavlov. Cond. lever latency	2.8	3.6	10.7	0.7	1.8	1.4	1.6	-1.9	-2.8	0.9	1.2	3.3	1.9
Pavlov. Cond. magazine entry latency	5.6	7.2	14.1	-1.6	-2.6	-2.4	-2.7	2.7	3.8	-1.7	-1.8	-3.7	-2.9
Pavlov. Cond. change in total contacts	2.8	3.0	10.8	-0.7	-1.9	-0.9	-1.2	1.7	2.8	0.0	-0.3	-3.3	-1.5
Pavlov. Cond. index score	4.4	5.6	14.8	-1.0	-2.2	-1.8	-2.1	2.4	3.4	-1.2	-1.4	-3.9	-2.9
Pavlov. Cond. latency score	4.0	5.1	12.7	-1.0	-2.0	-1.8	-2.0	2.3	3.2	-1.2	-1.4	-3.6	-2.8
Pavlov. Cond. lever contacts	4.3	5.0	14.0	-1.0	-2.2	-1.6	-1.9	2.3	3.3	-1.0	-1.3	-3.7	-2.2
Pavlov. Cond. magazine entry number	3.4	4.3	12.7	0.9	2.1	1.5	1.8	-2.1	-3.1	0.7	0.8	3.6	2.1
Pavlov. Cond. intertrial magazine entries	1.5	1.8	4.8	1.0	1.7	1.0	1.1	-1.4	-2.0	0.2	0.1	2.2	1.3
Pavlov. Cond. lever-magazine prob. diff.	5.4	6.7	16.5	-1.1	-2.4	-2.0	-2.3	2.6	3.6	-1.4	-1.6	-4.1	-3.1
Pavlov. Cond. response bias	3.8	4.7	15.1	-0.8	-2.2	-1.4	-1.8	2.1	3.3	-0.6	-0.8	-3.9	-2.2
Pavlov. Cond. lever latency	1.2	1.6	2.5	1.1	1.2	1.5	1.4	-1.6	-1.3	1.4	1.4	0.6	0.4
Pavlov. Cond. magazine entry latency	0.8	1.0	2.1	1.4	0.8	1.3	1.2	-0.6	-0.3	1.3	1.1	-0.6	0.5
Pavlov. Cond. change in total contacts	0.4	0.5	1.8	0.1	0.5	-0.6	-0.4	0.5	0.0	-1.3	-1.2	0.5	-0.5
Pavlov. Cond. index score	0.1	0.1	0.3	0.3	0.0	-0.2	-0.2	0.6	0.4	-0.2	-0.4	-0.5	-0.2
Pavlov. Cond. latency score	0.1	0.1	0.3	0.2	-0.1	-0.2	-0.2	0.6	0.5	-0.1	-0.4	-0.6	-0.1
Pavlov. Cond. lever contacts	1.7	2.4	4.0	-1.1	-1.3	-1.9	-1.7	2.0	1.7	-1.6	-1.6	-1.1	-1.0
Pavlov. Cond. magazine entry number	1.1	1.4	3.1	-1.8	-1.6	-1.4	-1.4	1.0	1.0	-1.0	-0.9	-0.3	-0.3
Pavlov. Cond. intertrial magazine entries	3.4	4.4	5.6	-2.1	-2.2	-2.4	-2.4	2.3	2.1	-2.0	-2.0	-1.5	-2.0
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	0.5	0.2	-0.0	0.0	0.5	0.4	-0.0	-0.2	-0.6	-0.2
Pavlov. Cond. response bias	0.4	0.6	1.2	-0.1	-0.4	-0.8	-0.7	1.1	0.9	-0.8	-0.8	-0.7	-0.8
Time in closed arm before self-admin	0.6	0.7	2.4	-0.8	-0.7	-0.8	-0.8	0.6	0.8	-1.1	-1.5	0.3	0.1
Time in closed arm after self-admin	0.9	0.9	1.8	0.9	1.3	0.9	0.9	-1.1	-1.3	-0.0	0.1	1.3	0.2
Time in open arm before self-admin	1.5	1.6	2.7	1.6	1.4	1.6	1.4	-1.4	-1.0	1.2	1.4	0.0	0.2
Time in open arm after self-admin	1.0	1.1	2.8	-1.4	-1.7	-1.1	-1.0	1.2	1.1	0.1	-0.0	-1.0	0.2
Bone: periosteal estimation	2.5	5.2	9.1	-2.9	-3.0	-2.6	-2.6	2.6	2.6	-1.7	-1.5	-1.7	-0.3
Bone: periosteal perimeter	1.6	2.7	4.1	-1.6	-2.0	-1.8	-1.9	2.0	1.9	-1.4	-1.2	-1.6	-0.5
Bone: post-yield work	4.8	6.6	12.4	-2.2	-2.0	-2.8	-2.7	2.6	2.3	-2.8	-2.6	-1.6	-3.5
Progressive ratio test 1 active lever presses	1.2	1.3	3.5	-0.4	-0.5	-0.9	-1.0	0.8	0.9	-1.7	-1.9	-0.4	-1.5
Progressive ratio test 1 breakpoint	1.2	1.2	3.3	-0.5	-0.4	-1.0	-1.0	0.9	0.9	-1.7	-1.8	-0.4	-1.5
Progressive ratio test 1 inactive lever presses	0.8	0.8	2.3	-0.6	-0.7	-0.9	-0.8	0.8	0.9	-1.3	-1.5	-0.3	-0.7
Progressive ratio test 2 active lever presses	0.8	0.8	2.7	-0.3	-0.2	-0.8	-0.8	0.6	0.7	-1.6	-1.5	0.1	-1.0
Progressive ratio test 2 breakpoint	0.8	0.8	2.8	-0.2	-0.1	-0.8	-0.8	0.6	0.7	-1.7	-1.5	-0.0	-1.1
Progressive ratio test 2 inactive lever presses	0.4	0.5	1.8	-0.0	0.1	-0.6	-0.5	0.4	0.3	-1.3	-1.3	0.1	-0.9
Incentive Sensitization - Responses	0.2	0.2	0.7	0.1	-0.0	-0.2	-0.4	0.3	0.5	-0.8	-0.4	-0.5	-0.8
Incentive Sensitization - Breakpoint	0.2	0.2	0.8	0.1	-0.0	-0.3	-0.4	0.3	0.5	-0.9	-0.5	-0.5	-0.8
Sum of active levers in priming session hrs 5-6	0.5	0.5	1.9	0.2	0.0	-0.3	-0.5	0.4	0.7	-0.9	-0.9	-0.8	-1.4
Progressive ratio	0.3	0.4	1.0	-0.0	0.6	-0.2	-0.1	-0.3	-0.6	-0.7	-0.8	1.0	-0.8
Food seeking constrained by brief footshock	1.8	2.2	2.6	1.3	1.5	1.5	1.6	-1.5	-1.5	1.6	1.5	1.3	1.5
Seeking ratio, punishment vs. effort	0.3	0.3	0.9	0.1	-0.5	0.2	-0.0	0.4	0.7	0.7	0.7	-1.0	0.7
Retroperitoneal fat weight	0.8	2.7	6.2	-0.8	-0.3	-1.9	-1.7	1.2	1.0	-2.5	-2.2	-0.1	-2.5
Reaction time number correct	0.3	0.5	1.4	1.2	1.0	0.6	0.6	-0.4	-1.0	0.2	0.4	-0.2	-0.7
Reaction time mean minus median	0.1	0.1	0.3	-0.5	-0.3	-0.3	-0.2	0.2	-0.0	-0.3	-0.0	0.1	-0.4
Reaction time mean minus median AUC	0.2	0.2	0.9	-0.0	0.5	-0.2	-0.0	-0.0	-0.5	-0.6	-0.4	0.4	-1.0
Reaction time num false alarms	1.8	2.4	5.2	0.6	0.9	1.6	1.6	-1.6	-1.4	2.1	1.5	0.9	2.3
Reaction time num false alarms AUC	1.0	1.3	2.9	0.6	0.7	1.3	1.2	-1.2	-0.9	1.7	1.2	0.3	1.7
Reaction time trials correct on left	0.3	0.5	1.4	1.2	1.0	0.6	0.6	-0.4	-1.0	0.2	0.4	-0.2	-0.7
Reaction time trials on left	0.3	0.5	1.3	1.2	0.9	0.5	0.5	-0.3	-0.9	0.2	0.4	-0.2	-0.8
Reaction time mean	0.6	0.8	1.3	-1.1	-0.6	-1.1	-0.9	0.9	0.9	-1.1	-1.0	-0.4	-0.8
Reaction time mean AUC	0.4	0.6	0.9	-0.7	-0.4	-0.9	-0.7	0.8	0.8	-1.0	-0.7	-0.6	-0.8
Median of all reaction times	0.7	1.0	1.5	-1.0	-0.7	-1.2	-1.0	1.0	1.2	-1.2	-1.2	-0.6	-0.8
Reaction time omissions	0.4	0.5	2.7	0.5	0.2	-0.2	-0.1	0.4	0.4	-0.1	-0.2	-1.3	-1.6
Reaction time false alarm rate	0.8	1.1	4.5	-0.1	0.1	1.0	0.9	-1.0	-0.4	1.6	1.1	0.4	2.1
Reaction time premature initiation rate	0.6	0.8	2.4	-1.5	-1.5	-0.7	-0.8	0.9	0.7	0.3	0.6	-0.6	-0.2
Reaction time premature initiations	0.2	0.3	1.0	-0.6	-0.8	-0.2	-0.3	0.5	0.1	0.6	1.0	-0.7	-0.4
Std. dev. reaction times	0.3	0.5	0.8	-0.9	-0.4	-0.9	-0.7	0.7	0.3	-0.9	-0.6	-0.0	-0.7
Reaction time trials completed	0.3	0.5	1.3	1.2	0.9	0.5	0.5	-0.3	-0.9	0.2	0.4	-0.2	-0.8
Reaction time trials AUC	0.2	0.3	0.9	1.0	0.8	0.4	0.4	-0.2	-0.8	0.1	0.3	-0.2	-0.7
Run reversals in cocaine runway, females	3.0	2.9	7.6	-2.8	-2.6	-1.9	-1.8	1.8	1.8	-0.7	-0.7	-0.4	0.4
Run reversals in cocaine runway, males	0.7	0.7	1.1	0.7	0.7	1.0	1.0	-1.0	-0.9	0.8	0.7	0.7	0.8
Latency to leave start box in cocaine runway	0.3	0.3	0.9	0.3	0.7	-0.2	0.1	-0.1	-0.9	-0.5	-0.7	0.9	-0.1
Latency to leave start box in cocaine runway, F	0.1	0.1	0.4	0.6	0.4	-0.0	0.0	0.3	-0.2	-0.2	-0.3	-0.4	-0.4
Latency to leave start box in cocaine runway, M	0.9	0.9	4.0	0.1	0.9	0.2	0.4	-0.9	-1.5	-0.2	-0.3	2.0	0.5
Std. dev. time between licks in bursts	0.6	0.7	2.1	-0.1	-0.6	-0.6	-0.8	0.8	1.2	-0.8	-0.9	-1.4	-0.7
Total sessions with >9 infusions	3.2	3.5	5.1	-2.3	-2.2	-2.2	-2.1	2.1	2.0	-2.1	-1.8	-0.3	-0.3
Short access day 1 total inactive lever presses	0.2	0.2	1.0	-0.1	0.2	-0.1	-0.1	-0.1	-0.0	-0.8	-1.0	0.8	0.2
Short access day 10 total inactive lever presses	1.5	1.6	2.8	0.9	1.1	1.4	1.5	-1.4	-1.2	1.1	0.8	1.4	1.7
Short access day 1 total infusions	1.4	1.5	3.8	-1.1	-0.9	-1.6	-1.3	1.2	0.7	-1.9	-1.7	0.6	-0.4
Short access day 10 total infusions	1.3	1.5	2.6	-1.2	-1.3	-1.4	-1.4	1.3	1.2	-1.6	-1.4	-0.3	-0.6
Short access total infusions	2.7	3.0	6.2	-1.7	-1.4	-2.1	-2.0	1.7	1.3	-2.5	-2.2	0.0	-1.1
Short access day 1 locomotion	0.3	0.3	0.7	-0.5	-0.2	-0.6	-0.3	0.4	0.2	-0.8	-0.8	0.8	0.1
Short access day 10 total locomotion	3.1	3.5	5.5	-1.5	-1.6	-1.8	-2.0	1.7	1.9	-2.3	-2.3	-1.3	-1.8
Short access total locomotion	3.3	3.4	7.9	-1.5	-0.9	-2.1	-2.0	1.6	1.1	-2.8	-2.8	0.2	-1.8
One hour access (0.3 mA shock)	2.7	3.1	5.8	-1.5	-1.4	-1.8	-2.1	1.6	1.7	-2.4	-2.1	-1.0	-1.6
Compulsive drug intake	1.1	1.1	3.6	-0.6	-0.5	-1.2	-1.2	1.1	0.6	-0.9	-0.5	-1.2	-1.9
One hour access (shock baseline)	0.2	0.3	0.8	0.4	0.5	0.5	0.4	-0.6	-0.5	-0.2	-0.3	0.9	0.6
Social response proportion	0.3	0.3	0.8	0.4	0.5	-0.5	-0.3	0.4	-0.3	-0.8	-0.9	-0.1	-0.6
Social responses	0.2	0.3	1.3	1.1	0.8	0.2	0.3	0.0	-0.3	-0.3	-0.4	-0.5	-0.7
Social time	0.9	1.1	2.4	1.4	1.6	0.9	1.1	-1.1	-1.3	0.6	0.4	0.9	0.7
Soleus weight	1.1	3.2	10.8	-3.3	-2.2	-2.1	-1.9	1.6	1.1	-1.4	-1.0	0.6	1.2
Bone: stiffness	1.7	2.7	6.9	-2.6	-2.5	-1.9	-1.8	1.9	1.5	-0.8	-0.7	-0.4	0.7
Tibialis anterior weight	3.7	12.7	27.6	-5.3	-4.9	-4.2	-4.2	3.8	3.6	-2.5	-2.3	-1.2	0.0
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.5	-0.5	-0.7	-0.4	-0.3	0.4	0.1	0.7	0.7	-0.5	0.3
Time to tail flick, vehicle, after self-admin	0.5	0.6	2.2	1.5	1.1	0.9	0.8	-0.6	-0.1	0.2	0.2	-0.5	-0.3
Time to tail flick, test, before self-admin	0.3	0.3	1.1	-0.1	-0.4	0.2	0.3	0.0	-0.1	0.9	1.0	-0.3	1.0
Time to tail flick, test, after self-admin	1.1	1.1	2.7	1.2	0.4	1.2	1.1	-0.6	-0.1	1.6	1.5	-1.1	0.4
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.9	0.6	0.4	0.0	-0.1	0.1	0.6	-0.9	-0.9	-0.5	-1.0
Delta time to tail flick, test, before/after SA	0.2	0.2	0.7	0.4	0.0	0.1	0.0	0.2	0.6	0.0	-0.2	-0.9	-0.8
Tibia length	0.1	0.3	1.4	0.0	0.4	0.1	0.3	-0.3	-0.7	0.0	-0.2	1.2	0.4
Ambulatory time before self-admin	0.7	0.8	2.8	0.1	0.5	0.9	0.8	-0.9	-0.5	0.1	0.7	1.7	1.2
Ambulatory time after self-admin	0.7	0.8	2.5	-1.6	-1.4	-0.4	-0.6	0.5	0.7	0.1	0.3	0.2	1.4
Bone: tissue strength	0.1	0.1	0.6	-0.1	-0.1	0.2	0.2	-0.1	0.1	0.4	0.4	0.1	0.8
Total heroin consumption	0.6	0.7	1.9	1.0	1.0	0.1	0.0	-0.3	0.2	-1.4	-1.0	-0.1	-1.4
Bone: trabecular number	0.3	0.5	1.4	-1.2	-0.9	-0.9	-0.7	0.6	0.4	-0.6	-0.4	0.2	0.5
Bone: trabecular spacing	0.3	0.4	2.0	1.1	0.4	0.3	0.2	0.2	0.4	0.2	-0.0	-1.4	-0.3
Bone: trabecular thickness	1.6	1.9	4.0	-2.0	-0.9	-1.7	-1.5	0.8	0.4	-2.0	-1.7	1.3	0.0
Bone: trabecular tissue density	0.1	0.2	1.2	0.0	0.1	0.3	0.3	-0.3	-0.2	0.1	-0.2	0.6	1.1
Water consumed over 24 hours	2.0	2.4	7.0	0.9	0.5	1.7	1.7	-1.1	-1.0	2.6	2.6	0.1	1.4
Number of responses in last shaping day	0.6	0.6	1.3	-0.8	-0.8	-0.9	-0.8	0.8	0.8	-1.0	-1.1	-0.2	-0.3