Hub : Genes

Smyd4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr10_60200371_60201453 0.09 0.06 4.5e-10 0.03 0.08 0.09 0.08 1.5e-04 1.8e-09 3.5e-10 1.0e-09
2 pVTA intron excision ratio chr10_60200371_60201453 0.12 0.08 2.1e-04 0.09 0.09 0.06 0.09 1.3e-04 1.0e-04 1.6e-03 9.2e-05
3 BLA intron excision ratio chr10_60200371_60201453 0.07 0.05 2.3e-03 0.03 0.04 0.03 0.01 8.1e-03 5.6e-03 1.2e-02 6.6e-02
4 Liver intron excision ratio chr10_60200371_60201453 0.03 0.02 6.2e-03 0.01 0.01 0.01 0.01 1.2e-02 1.7e-02 1.5e-02 2.0e-02
5 Liver isoform ratio NM_001105810.1 0.02 0.02 6.6e-03 0.02 0.01 0.01 0.01 5.6e-03 9.5e-03 1.6e-02 9.4e-03
6 Brain isoform ratio XM_006246674.4 0.05 0.04 2.2e-04 0.03 0.04 0.03 0.03 4.0e-04 1.1e-04 1.5e-03 1.6e-03
7 Brain intron excision ratio chr10_60200371_60201453 0.13 0.09 3.7e-10 0.1 0.12 0.11 0.11 1.7e-09 8.1e-11 1.4e-10 1.4e-10
8 Brain intron excision ratio chr10_60201227_60201453 0.06 0.04 1.3e-05 0.03 0.06 0.04 0.06 1.1e-03 3.1e-06 3.2e-04 7.3e-06
9 Brain gene expression Smyd4 0.04 0.03 5.9e-03 0.01 0.01 0.02 0.01 2.4e-02 2.2e-02 2.3e-03 1.7e-02
10 Eye intron excision ratio chr10_60200371_60201453 0.39 0.19 2.3e-04 0.14 0.24 0.23 0.2 3.1e-03 1.1e-04 2.1e-04 5.8e-04
11 RMTg intron excision ratio chr10_60200371_60201004 0.17 0.12 8.1e-04 0.14 0.15 0.13 0.15 1.5e-04 1.0e-04 2.3e-04 9.4e-05
12 Adipose intron excision ratio chr10_60200371_60201453 0.1 0.08 5.1e-09 0.06 0.06 0.06 0.06 3.4e-07 1.8e-07 3.0e-07 3.9e-07
13 PL intron excision ratio chr10_60200371_60201453 0.1 0.07 1.3e-10 0.1 0.1 0.1 0.1 2.1e-11 2.5e-11 1.4e-11 2.2e-11
14 Brain mRNA stability Smyd4 0.05 0.04 2.1e-04 0.04 0.04 0.04 0.03 2.9e-04 3.2e-04 3.2e-04 7.5e-04
15 Eye intron excision ratio chr10_60201227_60201453 0.26 0.16 7.3e-03 0.18 0.13 0.1 0.13 8.7e-04 4.8e-03 1.3e-02 5.4e-03
16 Liver gene expression Smyd4 0.05 0.04 5.3e-05 0.03 0.03 0.03 0.03 3.8e-04 2.0e-04 1.8e-04 6.7e-04
17 Adipose isoform ratio NM_001105810.1 0.03 0.03 5.0e-03 0.02 0.02 0.01 0.02 2.5e-03 5.1e-03 6.9e-03 4.9e-03
18 Adipose isoform ratio XM_006246674.4 0.03 0.03 2.0e-03 0.03 0.02 0.03 0.03 1.0e-04 1.8e-03 4.0e-04 3.3e-04
19 PL gene expression Smyd4 0.05 0.03 2.0e-04 0.02 0.03 0.03 0.02 1.0e-03 3.1e-04 4.0e-04 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density3.25.38.83.0-2.8-2.72.72.72.9-2.92.7-1.5-2.52.2-2.30.81.9-1.81.81.8-1.8-1.3
Area under the delay curve1.31.42.5-1.61.51.5-1.4-1.4-1.51.4-1.31.11.2-1.01.10.0-1.30.7-0.7-0.80.80.5
BMI with tail0.82.54.72.2-2.1-2.12.12.02.1-1.91.8-1.3-1.61.3-1.4-0.10.9-0.91.01.1-1.1-0.5
BMI without tail0.30.61.00.6-0.5-0.40.50.40.7-0.90.90.4-1.00.9-1.00.90.9-0.80.91.0-1.0-0.9
Body weight1.77.010.32.1-1.6-1.31.71.62.5-2.83.01.0-3.23.2-3.22.83.0-3.13.23.1-3.1-3.0
Weight adjusted by age0.60.71.71.3-1.1-1.01.01.11.1-1.00.9-0.6-0.80.8-0.80.10.4-0.60.60.6-0.6-0.3
Bone surface2.54.48.62.9-2.8-2.82.82.82.8-2.62.4-1.9-2.11.8-1.90.01.0-1.31.41.3-1.3-0.7
Bone volume2.74.79.23.0-2.9-2.92.92.92.9-2.72.4-1.9-2.11.9-1.90.21.1-1.31.41.3-1.3-0.7
Breakpoint value in progressive ratio session1.31.52.60.7-0.5-0.40.50.51.0-1.21.30.7-1.51.4-1.51.61.2-1.41.41.6-1.6-1.5
Number of licking bursts0.30.40.6-0.70.60.6-0.8-0.7-0.70.8-0.70.30.7-0.70.7-0.2-0.70.6-0.6-0.60.60.4
Context. condit. distance diff. score1.11.32.01.3-1.2-1.11.21.11.4-1.41.4-0.4-1.41.3-1.30.40.9-1.21.11.1-1.1-0.9
Locomotion velocity, session 13.63.87.01.9-1.6-1.41.71.62.0-2.22.30.1-2.32.2-2.21.72.6-2.12.12.1-2.1-1.8
Locomotion distance, session 10.60.71.61.2-1.2-1.21.31.21.1-1.00.9-0.8-0.80.7-0.70.10.7-0.50.40.4-0.4-0.1
Locomotion velocity, session 20.80.92.31.2-1.0-1.01.21.11.1-1.11.1-0.4-1.01.0-1.00.51.5-0.80.80.8-0.8-0.6
Locomotion distance, session 21.31.83.51.9-1.8-1.81.91.81.8-1.71.5-1.2-1.31.2-1.2-0.21.0-0.90.90.8-0.8-0.4
Locomotion velocity, session 33.33.97.4-2.72.62.6-2.6-2.7-2.62.4-2.21.62.0-1.71.80.1-1.11.3-1.3-1.31.30.7
Locomotion distance, session 30.10.10.30.1-0.2-0.30.20.10.00.1-0.2-0.60.3-0.30.4-0.3-0.50.4-0.4-0.40.40.5
Stereotopy head waving bouts, day 30.20.21.5-0.20.40.5-0.4-0.2-0.20.00.10.9-0.30.3-0.31.20.5-0.50.50.5-0.5-0.6
Stereotopy head waving duration, day 30.20.30.4-0.40.40.4-0.4-0.3-0.60.7-0.70.10.7-0.60.60.0-0.10.6-0.6-0.60.60.6
Locomotion velocity, session 70.70.81.71.3-1.3-1.31.21.21.2-1.00.9-1.1-0.70.6-0.6-0.60.6-0.40.30.3-0.3-0.0
Locomotion distance, session 71.21.53.01.7-1.7-1.71.61.71.6-1.51.3-1.3-1.11.0-1.0-0.60.7-0.70.60.6-0.6-0.2
Stereotopy head waving bouts, day 70.81.01.51.2-1.1-1.01.11.11.1-1.11.1-0.2-1.01.0-1.01.11.1-0.90.80.8-0.8-0.6
Stereotopy head waving duration, day 71.11.42.21.5-1.4-1.21.41.41.4-1.31.3-0.5-1.21.2-1.21.01.4-1.00.90.9-0.9-0.7
Locomotion velocity, session 80.40.51.01.0-1.0-1.01.00.90.9-0.80.7-0.7-0.60.5-0.5-0.20.9-0.30.30.3-0.3-0.1
Locomotion distance, session 82.23.24.62.0-1.8-1.71.81.72.1-2.12.1-0.5-2.12.0-2.00.81.8-1.81.71.7-1.7-1.4
Degree of sensitization distance1.21.21.81.1-0.9-0.80.81.01.2-1.31.3-0.0-1.31.2-1.30.31.3-1.11.21.2-1.2-1.0
Degree of sensitization stereotypy1.41.52.41.3-1.2-1.01.21.11.3-1.41.4-0.1-1.41.4-1.41.21.5-1.21.21.2-1.2-1.0
Conditioned locomotion0.70.81.2-0.70.50.4-0.6-0.6-0.80.9-1.0-0.31.1-1.11.1-0.9-1.11.1-1.1-1.01.01.0
Cocaine response after cond. corrected0.20.30.7-0.00.20.2-0.1-0.00.2-0.30.40.7-0.50.6-0.60.30.4-0.70.70.8-0.8-0.8
Cocaine response after cond. not corrected0.60.61.50.4-0.2-0.10.30.30.6-0.80.90.6-1.00.9-1.00.70.5-1.01.01.2-1.2-1.1
Cocaine response before conditioning1.01.21.81.3-1.2-1.21.21.21.4-1.31.3-0.5-1.21.1-1.10.70.7-0.90.91.0-1.0-0.7
Saline control response0.40.61.31.1-1.1-1.11.11.11.0-0.90.7-1.0-0.60.4-0.5-0.40.2-0.20.20.3-0.30.0
Bone: connectivity density4.36.812.23.5-3.3-3.33.33.33.4-3.33.0-2.0-2.72.4-2.50.41.8-1.81.91.8-1.8-1.1
Bone: cortical apparent density0.50.71.8-0.40.20.0-0.2-0.2-0.50.7-0.8-0.70.9-1.01.0-1.3-1.11.0-1.1-1.01.01.1
Bone: cortical area1.52.23.7-1.91.81.6-1.8-1.8-1.81.8-1.70.71.6-1.51.5-0.9-1.11.2-1.2-1.31.30.9
Bone: cortical porosity0.20.20.50.4-0.3-0.30.30.30.4-0.40.50.1-0.50.4-0.50.70.7-0.40.40.4-0.4-0.4
Bone: cortical porosity0.00.00.3-0.00.10.1-0.1-0.10.0-0.10.10.2-0.10.1-0.20.50.5-0.10.20.2-0.2-0.2
Bone: cortical thickness3.96.412.8-3.63.43.3-3.4-3.5-3.33.1-2.82.22.5-2.22.2-0.2-1.31.6-1.5-1.61.60.8
Bone: cortical thickness0.80.92.4-1.51.51.5-1.5-1.5-1.21.0-0.71.50.5-0.30.30.70.2-0.10.0-0.10.1-0.4
Bone: cortical tissue density0.40.51.6-0.20.0-0.1-0.1-0.1-0.30.5-0.6-0.70.7-0.80.8-1.3-1.00.9-0.9-0.90.91.0
Condit. Reinf. active minus inactive responses0.20.20.7-0.50.60.7-0.5-0.6-0.40.3-0.20.90.10.00.00.70.4-0.20.10.1-0.1-0.3
Condit. Reinf. active-inactive response ratio1.61.85.2-1.92.02.1-2.0-2.0-1.61.2-0.92.30.5-0.30.31.40.4-0.20.20.2-0.2-0.8
Condit. Reinf. active responses0.20.20.50.7-0.7-0.60.70.70.6-0.50.5-0.3-0.40.4-0.40.00.2-0.30.20.2-0.2-0.1
Condit. Reinf. inactive responses2.42.97.92.4-2.5-2.72.62.62.0-1.61.1-2.8-0.70.4-0.4-1.9-0.50.2-0.2-0.20.21.0
Incentive salience index mean0.20.31.0-0.40.40.6-0.3-0.4-0.20.00.11.0-0.30.4-0.40.90.9-0.50.50.5-0.5-0.7
Condit. Reinf. lever presses1.01.32.80.4-0.2-0.10.40.20.7-0.91.11.0-1.31.4-1.41.41.7-1.41.41.4-1.4-1.5
Condit. Reinf. active minus inactive responses0.30.40.80.9-0.8-0.80.90.90.8-0.70.7-0.4-0.60.5-0.5-0.30.3-0.40.40.4-0.4-0.2
Condit. Reinf. active-inactive response ratio0.10.10.6-0.30.40.4-0.3-0.3-0.20.1-0.00.8-0.10.1-0.2-0.10.5-0.20.20.3-0.3-0.4
Condit. Reinf. active responses0.71.02.51.6-1.6-1.51.51.61.3-1.10.9-1.3-0.60.5-0.5-0.4-0.1-0.10.10.2-0.20.3
Condit. Reinf. inactive responses1.82.26.92.2-2.3-2.42.22.21.7-1.30.9-2.6-0.50.2-0.2-0.9-0.90.3-0.3-0.40.41.0
Condit. Reinf. lever presses0.60.81.70.0-0.1-0.30.20.2-0.30.6-0.8-1.00.9-1.01.0-1.0-1.31.2-1.2-1.21.21.3
Condit. Reinf. lever reinforcers received0.60.92.31.5-1.5-1.51.51.51.2-0.90.7-1.3-0.50.3-0.3-0.5-0.30.0-0.00.0-0.00.4
Conditioned reinforcement - actives1.51.53.61.9-1.8-1.91.81.81.6-1.41.2-1.6-0.90.9-0.8-0.60.2-0.50.40.4-0.40.1
Conditioned reinforcement - inactives0.40.41.21.0-1.1-1.11.01.00.9-0.70.5-1.0-0.40.1-0.2-0.50.10.1-0.00.0-0.00.3
Conditioned locomotion0.10.20.4-0.20.10.1-0.1-0.1-0.30.4-0.5-0.30.5-0.30.5-0.5-0.60.3-0.4-0.50.50.6
Patch foraging indifference point 0 sec0.10.20.40.6-0.6-0.60.60.50.6-0.50.4-0.6-0.40.4-0.3-0.40.1-0.30.30.3-0.3-0.0
Patch foraging indifference point AUC0.60.72.6-0.1-0.0-0.1-0.0-0.0-0.40.6-0.8-0.70.9-1.01.0-0.8-1.61.1-1.1-1.01.01.2
Delay disc. indifference point, 0s delay0.00.00.10.3-0.3-0.10.30.40.1-0.10.10.2-0.10.2-0.10.3-0.1-0.20.20.1-0.1-0.0
Delay disc. indifference point, 16s delay0.70.71.3-1.10.90.9-0.9-0.9-1.01.0-1.00.50.9-0.80.9-0.2-0.80.7-0.7-0.80.80.5
Delay disc. indifference point, 2s delay1.01.11.7-1.31.31.3-1.3-1.2-1.31.2-1.20.91.1-0.91.0-0.0-1.10.7-0.7-0.80.80.5
Delay disc. indifference point, 24s delay0.20.20.5-0.70.60.5-0.6-0.6-0.60.5-0.50.20.5-0.40.4-0.3-0.50.3-0.3-0.30.30.2
Delay disc. indifference point, 4s delay0.70.71.8-1.11.21.3-1.1-1.1-1.11.0-0.81.40.6-0.30.50.7-0.70.1-0.1-0.30.3-0.1
Delay disc. indifference point, 8s delay0.60.61.2-1.11.11.1-1.1-1.1-1.01.0-0.90.90.7-0.60.7-0.1-0.90.4-0.4-0.50.50.2
Indifference point function ln k0.60.91.41.0-1.0-0.91.00.91.1-1.11.1-0.5-1.01.1-1.0-0.01.2-1.00.90.7-0.7-0.6
Indifference point function log k0.60.91.41.0-1.0-0.91.00.91.1-1.11.1-0.5-1.01.1-1.0-0.01.2-1.00.90.7-0.7-0.6
Patch foraging total patch changes 0 sec0.10.20.60.6-0.6-0.70.60.60.6-0.50.4-0.8-0.30.3-0.2-0.6-0.0-0.20.20.2-0.20.1
Patch foraging total patch changes 12 sec0.40.51.0-0.90.90.9-1.0-1.0-0.90.8-0.80.60.7-0.70.60.3-0.90.5-0.5-0.50.50.3
Patch foraging total patch changes 18 sec0.50.61.3-1.11.11.1-1.0-1.1-1.01.0-0.80.90.7-0.50.60.5-0.80.3-0.3-0.50.50.1
Patch foraging total patch changes 24 sec0.70.91.2-1.10.90.9-0.9-1.0-1.11.1-1.10.21.1-1.01.0-0.4-0.90.9-0.9-1.01.00.7
Patch foraging total patch changes 6 sec0.40.61.9-0.2-0.0-0.2-0.1-0.1-0.30.5-0.6-0.80.8-0.80.8-1.3-1.40.9-0.9-0.80.81.0
Patch foraging time to switch 0 sec0.81.34.6-1.51.71.8-1.6-1.6-1.20.9-0.62.10.2-0.10.01.60.4-0.40.40.3-0.3-0.9
Patch foraging water rate 0 sec0.40.72.80.8-1.0-1.20.90.90.6-0.40.1-1.70.2-0.20.3-1.4-0.50.5-0.5-0.50.51.0
Patch foraging water rate 12 sec0.00.00.10.1-0.1-0.10.10.10.2-0.20.2-0.2-0.20.3-0.2-0.10.3-0.30.20.1-0.1-0.1
Patch foraging water rate 18 sec2.12.95.32.3-2.2-2.32.32.22.2-2.11.8-1.8-1.61.5-1.4-0.61.4-1.11.10.9-0.9-0.5
Patch foraging water rate 24 sec0.20.31.10.8-0.8-0.80.80.90.5-0.40.2-1.1-0.10.00.0-0.5-0.50.2-0.2-0.30.30.5
Patch foraging water rate 6 sec0.30.41.1-0.30.10.0-0.2-0.2-0.40.6-0.7-0.50.8-0.70.8-1.0-0.50.8-0.8-0.90.90.9
Seeking ratio, delayed vs. immediate footshock1.71.92.9-1.20.90.8-0.9-0.9-1.31.5-1.6-0.31.7-1.71.7-1.1-1.71.7-1.7-1.61.61.5
Distance traveled before self-admin1.71.82.6-1.41.51.3-1.5-1.5-1.61.6-1.60.51.5-1.61.5-0.7-0.31.4-1.4-1.21.21.0
Distance traveled after self-admin0.10.10.4-0.20.30.4-0.4-0.3-0.30.2-0.10.6-0.00.0-0.10.60.5-0.20.20.1-0.1-0.3
Extensor digitorum longus weight3.714.631.05.6-5.5-5.55.45.45.1-4.64.0-4.2-3.42.8-2.9-1.11.8-1.71.81.8-1.8-0.4
Bone: elastic displacement0.60.71.1-0.60.40.3-0.5-0.5-0.70.8-0.9-0.41.0-1.01.0-0.8-0.71.0-1.0-1.11.11.0
Bone: elastic work3.24.17.9-2.82.62.6-2.7-2.8-2.62.5-2.31.62.0-1.91.8-0.1-1.11.4-1.3-1.51.50.8
Bone: endosteal estimation0.10.20.50.6-0.5-0.60.60.70.4-0.30.2-0.7-0.10.1-0.0-0.6-0.60.1-0.1-0.20.20.3
Bone: endosteal perimeter0.61.23.51.5-1.6-1.71.71.81.2-0.90.6-1.9-0.30.2-0.1-1.5-0.60.2-0.2-0.30.30.8
Epididymis fat weight3.37.811.23.1-2.6-2.52.82.73.2-3.33.3-0.5-3.33.2-3.21.62.7-2.82.82.8-2.8-2.3
Delta time in closed arm before/after self-admin0.50.51.3-0.30.10.1-0.2-0.1-0.50.6-0.7-0.50.8-0.90.8-1.1-0.91.0-0.9-0.90.90.9
Delta time in open arm before/after self-admin1.21.22.51.0-0.7-0.60.70.71.0-1.21.20.3-1.31.4-1.30.91.6-1.31.31.2-1.2-1.1
Diff in mean of infusions in LGA sessions0.91.03.10.3-0.10.10.00.20.5-0.70.91.0-1.11.0-1.21.71.0-1.21.21.3-1.3-1.4
Delay discount exponential model param1.21.32.61.6-1.5-1.51.51.51.5-1.41.2-1.2-1.10.8-0.9-0.21.2-0.60.60.7-0.7-0.3
Extinction: sum of active levers before priming1.91.92.81.7-1.6-1.51.61.61.6-1.61.5-0.6-1.41.6-1.40.31.2-1.31.31.1-1.1-0.8
Active lever presses in extinction session 61.21.22.01.4-1.2-1.11.31.31.3-1.31.2-0.4-1.21.2-1.10.41.1-1.01.00.9-0.9-0.6
Bone: final force0.50.92.8-1.31.41.5-1.4-1.4-1.00.7-0.41.70.10.0-0.01.0-0.0-0.40.40.3-0.3-0.8
Bone: final moment0.40.72.0-1.21.31.3-1.3-1.3-0.90.7-0.51.40.2-0.10.10.7-0.1-0.20.20.1-0.1-0.6
Food consumed during 24 hour testing period0.30.30.90.6-0.6-0.50.60.60.6-0.60.6-0.2-0.60.6-0.60.21.0-0.50.50.3-0.3-0.4
Glucose2.84.26.4-2.52.42.2-2.3-2.3-2.52.5-2.40.92.3-2.22.2-0.7-1.81.8-1.8-1.81.81.3
Heart weight0.10.20.40.2-0.1-0.0-0.00.10.3-0.40.50.4-0.50.4-0.60.40.6-0.50.50.6-0.6-0.6
Delay discount hyperbolic model param1.21.32.31.5-1.5-1.51.41.41.5-1.41.2-1.2-1.10.9-1.0-0.21.3-0.60.60.7-0.7-0.4
Intermittent access intake day 1-15 change1.31.33.80.4-0.5-0.80.50.5-0.00.4-0.7-1.90.9-1.11.1-2.0-1.11.4-1.4-1.41.41.7
Intermittent access intake escalation1.61.63.1-0.40.2-0.0-0.2-0.2-0.71.0-1.2-1.21.4-1.61.5-1.8-1.31.7-1.7-1.61.61.8
Intermittent access intake escalation 22.22.23.6-0.80.60.4-0.6-0.6-1.11.4-1.6-1.01.7-1.81.8-1.7-1.71.9-1.9-1.91.91.8
Intermitt. access day 1 inactive lever presses2.62.84.0-1.91.71.6-1.8-1.8-2.02.0-2.00.71.9-1.81.8-0.6-1.81.6-1.6-1.61.61.2
Intermitt. access day 15 inactive lever presses0.90.92.4-0.70.60.5-0.6-0.6-0.91.0-1.1-0.21.1-1.11.1-0.9-1.51.1-1.0-1.11.11.1
Intermitt. access escalation Index4.23.79.10.40.30.6-0.2-0.20.7-1.21.62.3-2.02.2-2.23.02.0-2.52.42.5-2.5-2.8
Intermittent access day 1 total infusions0.50.51.01.0-1.0-1.01.01.01.0-0.90.8-0.7-0.70.6-0.6-0.10.5-0.40.50.5-0.5-0.2
Intermittent access day 15 total infusions0.91.03.91.1-1.2-1.41.31.30.8-0.40.1-2.00.2-0.40.4-1.6-0.50.8-0.8-0.70.71.1
Intermittent access terminal intake (last 3 days)1.11.22.81.6-1.6-1.71.71.71.4-1.21.0-1.6-0.80.6-0.6-0.80.4-0.20.20.3-0.30.1
Intermittent access total infusions0.50.52.10.9-1.0-1.11.01.00.7-0.50.3-1.4-0.1-0.10.1-1.20.10.4-0.3-0.30.30.6
Intermittent access day 1 locomotion0.20.20.4-0.60.60.6-0.6-0.6-0.50.5-0.40.60.3-0.30.20.20.20.1-0.1-0.10.1-0.1
Intermittent access day 15 total locomotion0.40.50.9-0.30.10.1-0.2-0.2-0.50.6-0.7-0.50.8-0.90.9-0.9-0.61.0-0.9-0.80.81.0
Intermittent access total locomotion0.10.10.2-0.10.10.0-0.1-0.1-0.20.2-0.3-0.20.3-0.40.3-0.40.00.4-0.4-0.30.30.3
Intermittent access standard deviation3.13.29.10.0-0.5-0.80.50.5-0.40.9-1.3-2.51.7-2.01.9-3.0-2.22.4-2.3-2.22.22.6
Left kidney weight1.95.513.7-3.43.63.7-3.6-3.6-2.92.4-1.93.61.4-1.11.02.0-0.30.3-0.3-0.20.2-0.8
Right kidney weight1.64.512.1-3.13.33.4-3.3-3.3-2.62.0-1.53.51.0-0.80.62.10.00.0-0.00.1-0.1-1.0
Cocaine induced anxiety0.50.61.80.1-0.4-0.50.40.4-0.00.3-0.5-1.20.7-0.80.8-1.3-0.91.0-1.0-1.01.01.2
Post-drug Anxiety0.20.20.70.5-0.6-0.60.60.60.4-0.30.1-0.8-0.0-0.00.1-0.60.40.2-0.2-0.20.20.4
Baseline Anxiety0.20.20.4-0.00.20.2-0.2-0.20.1-0.20.30.6-0.40.4-0.40.60.6-0.50.50.5-0.5-0.6
Tail length2.37.023.2-0.51.11.5-1.1-1.10.3-1.11.83.9-2.32.6-2.74.83.2-3.23.13.2-3.2-3.9
Length with tail1.44.913.00.20.30.7-0.2-0.20.8-1.41.82.7-2.22.5-2.53.62.8-2.92.82.8-2.8-3.2
Length without tail1.22.74.01.4-1.2-1.01.21.21.6-1.81.90.3-1.92.0-1.91.41.8-1.92.01.8-1.8-1.7
Times rat made contact with spout0.91.12.9-1.51.61.6-1.6-1.6-1.21.0-0.71.70.4-0.30.31.20.7-0.10.10.1-0.1-0.6
Lifetime Intake0.50.62.30.9-1.0-1.11.01.00.6-0.40.2-1.50.0-0.20.2-1.3-0.20.5-0.5-0.40.40.8
Liver weight, left1.21.95.5-0.50.81.1-0.9-0.9-0.1-0.40.82.2-1.11.2-1.32.31.7-1.61.71.6-1.6-2.1
Liver weight, right0.91.54.50.10.20.4-0.1-0.20.4-0.71.01.5-1.21.3-1.42.11.6-1.51.61.5-1.5-1.7
Locomotor activity0.10.10.30.2-0.3-0.20.10.00.3-0.30.30.0-0.30.5-0.30.5-0.2-0.50.50.3-0.3-0.2
Locomotor testing distance0.00.00.10.1-0.3-0.20.10.00.2-0.20.2-0.1-0.20.3-0.10.30.4-0.30.30.2-0.2-0.1
Locomotor testing rearing0.20.31.10.9-1.0-1.00.80.90.7-0.50.4-1.0-0.20.1-0.1-0.3-0.30.1-0.1-0.10.10.4
Locomotion in novel chamber3.64.48.2-1.00.40.2-0.5-0.5-1.41.8-2.2-1.72.4-2.62.6-2.8-1.82.8-2.8-2.72.72.9
Locomotion in novel chamber post-restriction0.10.20.60.4-0.5-0.60.60.60.3-0.20.1-0.80.1-0.10.1-0.50.10.3-0.3-0.30.30.5
Fecal boli incidents, locomotor time 10.10.10.30.1-0.1-0.20.00.00.3-0.40.4-0.0-0.40.2-0.30.00.6-0.20.20.4-0.4-0.4
Change in fecal boli incidents, locomotor task0.40.41.1-0.80.91.0-0.7-0.7-0.70.6-0.41.10.3-0.10.20.8-0.3-0.10.10.0-0.0-0.3
Time >=10cm from walls, locomotor time 10.10.10.20.4-0.5-0.50.30.30.3-0.20.1-0.4-0.1-0.20.00.2-0.40.3-0.2-0.10.10.2
Bouts of movement, locomotor time 10.10.10.30.4-0.4-0.40.60.60.4-0.30.3-0.4-0.20.3-0.2-0.00.1-0.10.20.1-0.1-0.0
Total resting periods, locomotor time 10.10.10.30.4-0.5-0.50.50.50.3-0.30.2-0.6-0.10.1-0.1-0.2-0.20.1-0.0-0.00.00.2
Rest time, locomotor task time 10.30.30.70.1-0.3-0.30.30.3-0.10.2-0.4-0.80.5-0.60.6-0.6-0.80.8-0.8-0.70.70.8
Distance moved, locomotor task time 10.00.00.10.3-0.3-0.30.30.30.3-0.20.2-0.3-0.10.1-0.1-0.2-0.0-0.10.10.0-0.00.1
Vertical activity count, locomotor time 10.50.51.11.0-1.1-1.01.01.00.9-0.90.8-0.7-0.60.6-0.5-0.30.6-0.50.40.4-0.4-0.1
Time >=10cm from walls, locomotor time 20.70.81.2-1.11.01.1-1.0-1.0-1.11.0-0.90.90.8-0.90.80.6-1.10.7-0.7-0.60.60.3
Bouts of movement, locomotor time 20.10.10.3-0.50.50.5-0.4-0.4-0.50.4-0.30.40.3-0.10.20.1-0.3-0.00.0-0.10.1-0.0
Total resting periods, locomotor time 20.00.00.1-0.10.10.2-0.1-0.1-0.10.00.00.1-0.00.2-0.1-0.0-0.0-0.30.20.1-0.1-0.2
Rest time, locomotor task time 20.10.10.40.3-0.5-0.60.30.30.4-0.40.3-0.6-0.2-0.1-0.1-0.3-0.20.2-0.20.1-0.10.1
Distance moved, locomotor task time 20.40.41.00.1-0.1-0.10.30.3-0.30.5-0.7-0.30.7-0.70.8-0.5-0.80.8-0.8-0.90.91.0
Vertical activity count, locomotor time 20.20.30.5-0.50.60.6-0.5-0.5-0.70.7-0.70.50.6-0.40.6-0.0-0.10.3-0.4-0.50.50.3
Light reinforcement 10.00.00.20.3-0.3-0.20.20.20.2-0.10.1-0.1-0.10.0-0.1-0.10.4-0.00.0-0.10.10.1
Light reinforcement 21.62.14.8-2.12.02.1-2.2-2.0-1.91.7-1.51.71.3-1.21.10.5-0.00.8-0.8-0.80.80.2
Bone: marrow area0.10.20.50.6-0.5-0.60.60.70.4-0.30.2-0.7-0.10.1-0.0-0.6-0.60.1-0.1-0.20.20.3
Bone: maximum diameter0.40.73.60.2-0.4-0.50.40.40.00.2-0.4-1.10.6-0.70.7-1.9-0.90.9-0.9-1.01.01.1
Bone: maximum force0.50.92.4-1.51.51.5-1.5-1.5-1.20.9-0.71.50.5-0.30.30.6-0.1-0.00.0-0.00.0-0.5
Bone: maximum moment0.40.82.0-1.41.41.4-1.4-1.4-1.10.9-0.81.20.6-0.50.40.3-0.20.2-0.2-0.20.2-0.2
Mean time between licks in bursts0.40.61.9-0.10.30.4-0.3-0.30.1-0.30.51.0-0.70.8-0.81.40.7-0.90.91.0-1.0-1.1
Mean num. licks in bursts0.40.41.5-0.40.50.6-0.4-0.5-0.1-0.10.31.0-0.40.5-0.51.01.2-0.70.70.7-0.7-0.9
Cd content in liver0.80.82.01.3-1.2-1.21.41.21.2-1.11.0-0.8-0.80.8-0.7-0.4-0.2-0.50.50.5-0.5-0.2
Co content in liver0.10.20.5-0.50.50.5-0.5-0.5-0.50.4-0.40.30.4-0.30.30.1-0.70.2-0.3-0.20.20.1
Cu content in liver0.60.71.9-1.31.31.4-1.3-1.3-1.10.9-0.71.30.5-0.40.40.5-0.20.1-0.1-0.10.1-0.2
Fe content in liver0.50.61.4-0.20.30.5-0.3-0.30.1-0.30.51.2-0.70.8-0.81.20.9-1.01.01.0-1.0-1.1
K content in liver1.11.14.9-0.71.01.2-1.0-1.0-0.50.10.21.9-0.50.6-0.72.20.8-1.01.01.0-1.0-1.4
Mg content in liver0.10.10.3-0.0-0.0-0.00.00.0-0.10.2-0.2-0.20.2-0.30.2-0.0-0.60.3-0.3-0.30.30.3
Mn content in liver0.20.20.50.7-0.7-0.70.70.70.6-0.60.5-0.6-0.40.4-0.4-0.1-0.1-0.20.20.2-0.2-0.1
Na content in liver2.12.24.6-2.12.12.1-2.1-2.1-2.01.8-1.61.71.3-1.11.10.8-0.40.7-0.7-0.70.70.2
Rb content in liver0.81.12.61.5-1.6-1.61.61.61.3-1.10.9-1.5-0.60.5-0.5-0.70.3-0.10.10.1-0.10.3
Se content in liver0.70.91.8-1.31.31.3-1.3-1.3-1.21.1-1.01.00.8-0.60.70.2-1.20.3-0.4-0.50.50.1
Sr content in liver0.60.61.11.0-1.0-1.00.91.01.0-0.90.9-0.7-0.80.6-0.7-0.30.7-0.50.50.5-0.5-0.3
Zn content in liver0.40.41.30.8-0.9-1.00.80.90.7-0.50.4-1.1-0.20.0-0.1-1.1-0.40.2-0.2-0.10.10.4
Bone: minimum diameter0.51.02.4-1.51.51.5-1.5-1.4-1.31.1-0.91.30.7-0.60.60.3-0.30.2-0.2-0.30.3-0.1
Time in familiar zone, hab. session 11.11.03.81.2-1.4-1.51.21.31.0-0.70.4-1.9-0.1-0.10.1-1.8-0.50.4-0.5-0.50.50.9
Time in novel zone, hab. session 10.90.93.3-1.21.31.5-1.4-1.2-1.00.7-0.41.80.10.0-0.01.50.4-0.40.40.4-0.4-0.8
Total zone transitions, hab. session 11.41.95.12.1-2.1-2.22.12.21.7-1.31.0-2.3-0.70.5-0.4-1.10.10.0-0.1-0.10.10.7
Total locomotion distance, hab. session 10.50.61.51.2-1.2-1.21.21.21.0-0.90.7-1.1-0.60.5-0.5-0.30.1-0.20.20.2-0.20.1
Locomotion velocity, hab. session 10.50.71.91.3-1.3-1.41.31.31.1-0.90.7-1.3-0.50.4-0.4-0.60.0-0.10.10.1-0.10.3
Time in familiar zone, hab. session 21.31.33.21.7-1.7-1.81.61.71.5-1.31.1-1.6-0.90.7-0.7-0.30.2-0.30.30.3-0.30.1
Time in novel zone, hab. session 23.13.17.1-2.62.62.7-2.5-2.6-2.42.1-1.82.31.4-1.11.20.4-0.50.6-0.6-0.60.6-0.0
Total zone transitions, hab. session 20.91.12.21.5-1.4-1.41.51.41.4-1.31.2-0.8-1.11.0-1.00.30.7-0.70.70.7-0.7-0.4
Total locomotion distance, hab. session 20.10.10.20.4-0.3-0.30.40.30.4-0.50.5-0.0-0.50.5-0.40.40.1-0.40.40.4-0.4-0.3
Locomotion velocity, hab. session 20.10.10.10.3-0.3-0.20.30.20.3-0.30.40.0-0.40.4-0.40.30.1-0.30.30.3-0.3-0.3
Novel to familiar place preference ratio0.40.42.1-0.30.0-0.0-0.1-0.1-0.30.5-0.6-0.60.7-0.70.7-1.4-0.80.8-0.8-0.80.80.8
Novelty place preference0.10.11.0-0.30.10.1-0.2-0.2-0.20.3-0.3-0.30.3-0.40.4-1.0-0.30.4-0.4-0.40.40.4
Time in novel zone, NPP test0.00.00.60.0-0.1-0.20.10.10.1-0.0-0.0-0.30.1-0.10.1-0.8-0.10.1-0.1-0.10.10.2
Total zone transitions, NPP test0.81.23.01.6-1.6-1.71.71.71.4-1.20.9-1.6-0.70.6-0.5-0.20.3-0.20.20.1-0.10.3
Total locomotion distance, NPP test0.30.41.60.8-0.8-0.90.90.80.5-0.30.1-1.20.1-0.20.2-0.5-0.50.4-0.5-0.50.50.7
Locomotion velocity, NPP test0.40.61.60.3-0.5-0.60.60.50.00.2-0.4-1.20.6-0.70.7-0.9-0.90.9-0.9-0.90.91.2
Intraocular pressure1.01.43.60.5-0.8-1.00.80.70.10.3-0.6-1.90.9-1.21.1-1.9-1.21.5-1.5-1.41.41.7
Delta distance traveled before/after self-admin1.92.13.21.2-1.1-0.81.11.11.4-1.51.60.3-1.71.8-1.71.51.2-1.71.71.6-1.6-1.5
Delta ambulatory time before/after self-admin1.51.62.41.1-1.0-0.81.01.01.2-1.41.50.2-1.51.6-1.51.41.2-1.51.51.4-1.4-1.3
Parametrial fat weight8.316.222.53.9-3.3-2.83.33.24.2-4.54.70.5-4.74.7-4.73.84.3-4.44.34.4-4.4-3.9
Pavlov. Cond. lever latency0.30.41.60.6-0.7-0.80.50.70.4-0.2-0.0-1.30.2-0.40.3-0.9-1.00.5-0.5-0.50.50.8
Pavlov. Cond. magazine entry latency0.60.71.40.3-0.1-0.00.20.10.5-0.70.90.8-1.01.1-1.00.90.8-1.21.11.1-1.1-1.2
Pavlov. Cond. change in total contacts0.40.40.9-0.90.91.0-0.8-0.9-0.90.8-0.70.80.6-0.40.50.2-0.30.3-0.3-0.30.30.1
Pavlov. Cond. index score0.70.91.80.10.10.30.0-0.10.3-0.60.81.2-0.91.1-1.01.31.3-1.21.21.2-1.2-1.3
Pavlov. Cond. latency score0.91.12.7-0.10.30.5-0.2-0.30.2-0.50.71.5-1.01.1-1.11.61.4-1.31.31.3-1.3-1.5
Pavlov. Cond. lever contacts0.30.41.3-0.40.50.7-0.3-0.6-0.20.00.11.1-0.30.5-0.40.91.0-0.60.60.6-0.6-0.8
Pavlov. Cond. magazine entry number0.20.20.4-0.20.10.0-0.2-0.1-0.30.4-0.5-0.40.5-0.60.5-0.4-0.30.6-0.6-0.60.60.6
Pavlov. Cond. intertrial magazine entries0.60.72.50.9-1.0-1.11.01.00.5-0.2-0.0-1.60.3-0.40.4-1.1-0.80.8-0.8-0.70.71.1
Pavlov. Cond. lever-magazine prob. diff.0.50.61.20.2-0.00.10.10.00.4-0.60.70.9-0.91.0-0.91.11.1-1.11.01.0-1.0-1.1
Pavlov. Cond. response bias0.30.40.70.2-0.10.00.20.10.3-0.50.60.6-0.70.8-0.70.60.6-0.80.80.8-0.8-0.9
Pavlov. Cond. lever latency1.11.52.11.3-1.1-1.01.21.11.4-1.41.5-0.2-1.41.4-1.40.31.0-1.31.31.4-1.4-1.1
Pavlov. Cond. magazine entry latency0.80.92.3-1.51.51.5-1.5-1.5-1.21.0-0.81.30.7-0.60.50.7-0.10.3-0.3-0.10.1-0.2
Pavlov. Cond. change in total contacts0.60.91.4-1.21.21.1-1.2-1.1-1.21.1-1.10.71.0-0.90.90.3-0.60.7-0.7-0.70.70.4
Pavlov. Cond. index score1.41.82.5-1.51.41.3-1.4-1.4-1.61.6-1.60.41.5-1.51.5-0.2-1.11.3-1.3-1.31.31.0
Pavlov. Cond. latency score1.72.13.1-1.61.51.3-1.5-1.5-1.71.7-1.70.31.7-1.71.7-0.4-1.21.5-1.5-1.51.51.2
Pavlov. Cond. lever contacts0.60.81.3-1.11.11.0-1.1-1.1-1.11.1-1.00.51.0-0.90.90.2-0.50.8-0.8-0.80.80.5
Pavlov. Cond. magazine entry number1.01.22.71.6-1.6-1.51.61.61.4-1.31.1-1.1-1.00.9-0.8-0.70.6-0.60.60.5-0.5-0.2
Pavlov. Cond. intertrial magazine entries1.62.04.32.1-2.1-2.02.12.01.9-1.71.5-1.3-1.31.2-1.2-0.40.5-0.80.80.8-0.8-0.3
Pavlov. Cond. lever-magazine prob. diff.1.21.62.2-1.41.31.2-1.3-1.3-1.51.5-1.50.41.4-1.41.4-0.2-1.01.3-1.3-1.21.21.0
Pavlov. Cond. response bias0.91.22.2-1.51.41.4-1.5-1.4-1.41.3-1.20.81.1-1.01.00.4-0.70.8-0.8-0.80.80.4
Time in closed arm before self-admin2.32.75.11.4-1.1-1.01.11.21.6-1.81.90.3-1.91.8-1.91.52.3-1.71.71.9-1.9-1.7
Time in closed arm after self-admin0.10.10.2-0.30.30.3-0.3-0.2-0.30.3-0.30.10.2-0.40.2-0.10.40.3-0.3-0.20.20.1
Time in open arm before self-admin5.05.48.2-2.82.42.3-2.4-2.4-2.82.9-2.80.82.7-2.42.5-0.8-2.52.1-2.1-2.22.21.7
Time in open arm after self-admin0.80.91.5-1.21.01.0-0.9-1.0-1.21.2-1.20.41.1-0.81.0-0.3-1.10.7-0.7-1.01.00.7
Bone: periosteal estimation0.30.50.8-0.90.80.7-0.8-0.7-0.90.9-0.80.30.8-0.70.7-0.7-0.90.6-0.6-0.70.70.5
Bone: periosteal perimeter0.30.41.8-0.20.1-0.10.00.0-0.30.4-0.6-0.60.7-0.60.7-1.3-1.00.7-0.8-0.90.90.9
Bone: post-yield work0.30.50.80.4-0.3-0.20.30.30.6-0.70.80.4-0.80.8-0.80.50.9-0.80.80.9-0.9-0.8
Progressive ratio test 1 active lever presses0.30.30.70.8-0.6-0.70.80.80.7-0.70.6-0.6-0.50.4-0.4-0.30.8-0.30.30.4-0.4-0.2
Progressive ratio test 1 breakpoint0.70.71.51.2-1.0-1.01.11.11.1-1.01.0-0.7-0.90.8-0.8-0.10.7-0.50.60.7-0.7-0.4
Progressive ratio test 1 inactive lever presses0.60.61.3-0.70.50.5-0.6-0.6-0.80.9-0.9-0.10.9-1.00.9-0.6-1.10.9-0.9-0.90.90.8
Progressive ratio test 2 active lever presses0.30.41.50.7-0.8-0.90.90.90.6-0.40.2-1.2-0.0-0.10.1-1.0-0.00.3-0.3-0.30.30.6
Progressive ratio test 2 breakpoint0.40.41.80.7-0.8-0.90.80.80.5-0.30.1-1.30.1-0.20.2-1.1-0.30.5-0.4-0.40.40.7
Progressive ratio test 2 inactive lever presses0.40.51.90.2-0.4-0.50.40.40.00.2-0.4-1.20.6-0.60.7-1.4-0.20.8-0.8-0.80.81.0
Incentive Sensitization - Responses0.20.20.50.2-0.5-0.50.40.40.2-0.1-0.0-0.70.1-0.30.2-0.5-0.50.4-0.5-0.30.30.5
Incentive Sensitization - Breakpoint0.10.10.40.1-0.3-0.40.30.30.1-0.0-0.1-0.60.2-0.30.3-0.5-0.50.5-0.5-0.30.30.5
Sum of active levers in priming session hrs 5-62.42.33.81.3-1.0-0.81.01.01.4-1.61.70.5-1.81.7-1.81.51.9-1.71.71.8-1.8-1.6
Progressive ratio0.50.51.90.7-0.9-1.00.80.90.5-0.30.1-1.40.2-0.40.3-1.1-0.60.7-0.6-0.60.60.9
Food seeking constrained by brief footshock0.10.10.2-0.40.40.3-0.4-0.4-0.40.4-0.40.10.4-0.40.4-0.3-0.00.4-0.4-0.40.40.3
Seeking ratio, punishment vs. effort0.50.72.0-1.11.31.3-1.2-1.3-1.00.8-0.61.40.4-0.10.20.80.4-0.20.10.1-0.1-0.4
Retroperitoneal fat weight0.00.00.2-0.10.10.1-0.2-0.2-0.10.1-0.00.3-0.0-0.0-0.00.5-0.0-0.0-0.00.0-0.0-0.1
Reaction time number correct0.10.10.20.3-0.3-0.10.20.30.3-0.30.30.2-0.30.4-0.40.3-0.2-0.40.40.3-0.3-0.3
Reaction time mean minus median0.30.41.50.1-0.2-0.30.10.1-0.10.3-0.4-0.70.6-0.70.6-1.0-1.20.8-0.8-0.80.80.9
Reaction time mean minus median AUC0.70.92.61.3-1.4-1.51.31.41.0-0.70.5-1.6-0.2-0.1-0.0-1.1-0.50.4-0.4-0.40.40.8
Reaction time num false alarms0.91.23.80.6-1.0-1.10.70.80.30.1-0.4-1.90.7-0.90.9-1.8-1.01.2-1.2-1.11.11.5
Reaction time num false alarms AUC0.81.23.90.5-0.9-1.00.60.70.20.1-0.4-1.90.7-1.00.9-2.0-1.01.2-1.3-1.21.21.5
Reaction time trials correct on left0.10.10.20.3-0.3-0.10.20.30.3-0.30.30.2-0.30.4-0.40.3-0.2-0.40.40.3-0.3-0.3
Reaction time trials on left0.10.10.10.3-0.3-0.20.20.30.3-0.30.30.1-0.30.4-0.30.3-0.3-0.40.30.3-0.3-0.3
Reaction time mean0.10.20.7-0.40.30.3-0.4-0.4-0.40.4-0.40.00.4-0.50.4-0.5-0.80.5-0.5-0.50.50.3
Reaction time mean AUC0.40.61.3-0.60.40.3-0.5-0.5-0.60.7-0.8-0.20.8-0.90.8-0.9-1.20.9-0.9-0.90.90.8
Median of all reaction times0.20.30.5-0.70.70.6-0.7-0.7-0.60.6-0.60.40.5-0.50.5-0.3-0.60.4-0.4-0.50.50.2
Reaction time omissions0.00.00.2-0.20.10.2-0.3-0.3-0.10.1-0.10.20.1-0.10.1-0.0-0.50.1-0.1-0.00.0-0.0
Reaction time false alarm rate0.70.93.10.5-0.8-1.00.60.70.20.1-0.4-1.80.6-0.90.8-1.8-0.61.2-1.2-1.01.01.4
Reaction time premature initiation rate0.40.50.90.9-0.9-1.00.90.90.9-0.80.7-0.9-0.60.5-0.5-0.50.9-0.40.30.0-0.0-0.1
Reaction time premature initiations0.40.61.21.1-1.1-1.11.11.11.0-0.90.8-0.8-0.70.7-0.6-0.40.7-0.50.50.2-0.2-0.1
Std. dev. reaction times0.30.51.60.1-0.2-0.30.00.1-0.10.3-0.4-0.80.5-0.70.6-1.1-1.30.8-0.8-0.90.90.9
Reaction time trials completed0.10.10.10.3-0.3-0.20.20.30.3-0.30.30.1-0.30.4-0.30.3-0.3-0.40.30.3-0.3-0.3
Reaction time trials AUC0.10.10.10.3-0.3-0.20.20.30.2-0.20.30.1-0.30.4-0.30.2-0.3-0.30.30.3-0.3-0.2
Run reversals in cocaine runway, females0.80.83.1-0.0-0.1-0.20.10.1-0.30.5-0.7-0.90.8-0.90.9-1.2-1.81.1-1.1-1.01.01.2
Run reversals in cocaine runway, males0.50.51.60.6-0.7-0.80.70.70.3-0.1-0.1-1.30.3-0.40.4-1.30.10.7-0.7-0.70.70.9
Latency to leave start box in cocaine runway0.10.10.3-0.40.50.5-0.5-0.4-0.40.3-0.20.60.2-0.10.10.4-0.3-0.00.0-0.10.1-0.1
Latency to leave start box in cocaine runway, F0.20.20.7-0.50.50.6-0.5-0.5-0.30.2-0.00.8-0.10.2-0.20.7-0.0-0.30.30.2-0.2-0.5
Latency to leave start box in cocaine runway, M0.10.10.30.10.10.2-0.0-0.00.0-0.10.10.4-0.20.2-0.20.50.5-0.30.30.3-0.3-0.3
Std. dev. time between licks in bursts0.20.30.70.8-0.8-0.80.80.70.7-0.60.5-0.7-0.40.4-0.4-0.40.3-0.20.20.2-0.20.0
Total sessions with >9 infusions0.10.10.30.6-0.4-0.40.50.50.4-0.40.3-0.4-0.30.2-0.2-0.30.2-0.10.20.2-0.2-0.1
Short access day 1 total inactive lever presses0.20.20.30.5-0.4-0.40.50.50.5-0.60.6-0.1-0.60.5-0.60.10.1-0.40.50.5-0.5-0.4
Short access day 10 total inactive lever presses0.30.31.1-0.80.80.8-0.8-0.8-0.60.4-0.31.00.1-0.10.00.8-0.6-0.10.10.1-0.1-0.4
Short access day 1 total infusions1.01.13.60.2-0.3-0.50.40.4-0.20.5-0.7-1.50.9-1.01.0-1.9-1.31.2-1.2-1.21.21.5
Short access day 10 total infusions0.60.72.11.1-1.2-1.31.21.20.9-0.70.5-1.4-0.30.1-0.2-1.0-0.20.2-0.1-0.10.10.5
Short access total infusions0.70.82.80.8-0.8-1.00.90.90.4-0.1-0.1-1.70.4-0.50.5-1.6-1.00.8-0.8-0.70.71.1
Short access day 1 locomotion0.40.51.5-0.10.1-0.0-0.1-0.1-0.40.5-0.6-0.70.7-0.70.8-1.2-1.00.8-0.7-0.90.90.9
Short access day 10 total locomotion0.50.50.8-0.70.70.7-0.8-0.8-0.90.9-0.90.10.8-0.80.8-0.5-0.70.7-0.7-0.80.80.6
Short access total locomotion0.40.41.1-0.20.20.1-0.2-0.2-0.40.6-0.7-0.50.7-0.80.8-0.9-1.10.8-0.8-0.80.80.9
One hour access (0.3 mA shock)1.11.24.01.6-1.6-1.71.71.71.2-0.90.6-2.0-0.40.2-0.2-1.4-0.00.2-0.2-0.20.20.7
Compulsive drug intake0.60.63.1-0.20.40.6-0.4-0.4-0.1-0.20.41.1-0.50.8-0.61.11.8-1.00.90.8-0.8-1.0
One hour access (shock baseline)0.81.03.41.2-1.3-1.41.31.30.9-0.60.3-1.80.0-0.30.2-1.4-0.90.6-0.6-0.50.51.0
Social response proportion3.13.45.80.9-0.6-0.40.70.71.3-1.71.91.2-2.12.3-2.22.12.2-2.42.42.4-2.4-2.4
Social responses2.02.64.01.4-1.1-0.91.21.21.5-1.71.80.4-1.82.0-1.81.71.8-1.91.91.9-1.9-1.6
Social time2.73.65.02.1-1.8-1.61.91.92.1-2.22.2-0.3-2.22.2-2.11.31.7-2.02.01.9-1.9-1.6
Soleus weight3.710.815.53.2-2.6-2.42.72.73.5-3.73.90.2-3.93.8-3.82.73.9-3.53.53.6-3.6-3.1
Bone: stiffness1.01.62.60.8-0.5-0.40.50.61.1-1.31.40.7-1.51.6-1.61.51.3-1.61.61.6-1.6-1.6
Tibialis anterior weight6.622.442.96.5-6.3-6.26.26.26.2-5.95.4-3.9-4.84.2-4.30.02.8-3.13.13.2-3.2-1.7
Time to tail flick, vehicle, before self-admin5.25.48.22.9-2.6-2.52.52.62.9-2.92.8-1.0-2.62.5-2.50.61.5-2.12.12.1-2.1-1.6
Time to tail flick, vehicle, after self-admin0.70.82.41.1-1.4-1.41.31.41.0-0.70.5-1.5-0.30.3-0.2-1.0-0.30.1-0.0-0.20.20.6
Time to tail flick, test, before self-admin0.40.40.80.9-0.8-0.80.80.80.8-0.80.7-0.5-0.70.7-0.60.20.4-0.60.60.4-0.4-0.3
Time to tail flick, test, after self-admin0.40.41.30.2-0.1-0.00.20.20.4-0.50.60.5-0.60.8-0.70.71.2-0.80.90.7-0.7-0.7
Delta time to tail flick, vehicle, before/after SA1.41.42.6-0.80.40.3-0.4-0.3-0.91.2-1.3-0.81.4-1.41.5-1.4-1.11.4-1.4-1.61.61.6
Delta time to tail flick, test, before/after SA0.00.00.10.1-0.2-0.20.20.20.1-0.0-0.0-0.20.0-0.00.1-0.30.10.1-0.1-0.10.10.2
Tibia length0.82.27.8-1.31.61.8-1.6-1.6-0.80.30.22.8-0.60.8-0.92.50.5-1.31.41.4-1.4-2.0
Ambulatory time before self-admin1.91.94.0-2.01.81.8-1.9-1.9-1.81.7-1.51.11.4-1.41.3-0.1-0.41.0-1.1-0.90.90.5
Ambulatory time after self-admin1.01.13.6-0.30.50.7-0.5-0.5-0.0-0.30.51.6-0.80.9-0.91.91.7-1.21.21.2-1.2-1.5
Bone: tissue strength1.61.63.2-1.81.71.7-1.8-1.7-1.61.5-1.31.31.1-1.11.00.4-1.10.7-0.7-0.60.60.2
Total heroin consumption4.04.66.72.2-1.7-1.51.81.82.2-2.42.50.1-2.52.6-2.51.72.3-2.42.42.3-2.3-2.0
Bone: trabecular number3.25.19.23.0-2.9-2.82.82.82.9-2.82.6-1.7-2.42.1-2.20.51.5-1.61.61.6-1.6-1.0
Bone: trabecular spacing0.50.71.2-1.00.91.0-0.9-0.9-1.11.1-1.00.51.0-0.80.90.0-0.70.7-0.7-0.70.70.5
Bone: trabecular thickness0.20.30.50.7-0.6-0.70.70.70.7-0.70.6-0.5-0.50.5-0.5-0.20.4-0.40.30.3-0.3-0.2
Bone: trabecular tissue density1.92.74.2-2.01.91.8-1.8-1.8-2.02.0-1.90.81.8-1.71.7-0.8-1.61.4-1.4-1.51.51.0
Water consumed over 24 hours0.60.72.1-0.70.81.0-0.9-0.8-0.40.10.11.5-0.40.5-0.51.51.2-0.80.80.6-0.6-1.1
Number of responses in last shaping day1.01.01.6-0.90.80.7-0.7-0.7-1.01.1-1.2-0.21.2-1.21.2-1.0-1.31.2-1.2-1.11.11.0