Hub : Genes

Fads3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Fads3 0.05 0.03 5.0e-06 0.02 0.03 0.02 0.02 2.8e-03 2.5e-04 4.3e-03 1.7e-03
2 Liver gene expression Fads3 0.04 0.03 1.3e-03 0.01 0.02 0.01 0.01 1.7e-02 6.2e-03 7.1e-03 9.8e-03
3 IL gene expression Fads3 0.22 0.14 2.9e-04 0.08 0.11 0.03 0.08 5.0e-03 1.6e-03 7.1e-02 6.4e-03
4 NAcc gene expression Fads3 0.19 0.08 0.0e+00 0.27 0.27 0.26 0.27 1.5e-40 7.6e-41 5.5e-40 6.6e-41
5 IC gene expression Fads3 0.24 0.12 7.3e-09 0.18 0.16 0.16 0.16 5.8e-08 3.3e-07 3.6e-07 3.0e-07
6 pVTA gene expression Fads3 0.13 0.08 3.5e-09 0.08 0.11 0.1 0.1 2.9e-07 2.0e-09 2.1e-08 1.1e-08
7 Brain gene expression Fads3 0.14 0.07 3.1e-10 0.07 0.08 0.08 0.08 3.4e-07 2.9e-08 5.5e-08 6.1e-08
8 PL gene expression Fads3 0.16 0.08 5.6e-17 0.14 0.16 0.16 0.15 2.2e-15 6.8e-17 2.9e-17 3.9e-16
9 BLA gene expression Fads3 0.13 0.1 3.0e-05 0.1 0.09 0.12 0.09 6.1e-06 2.3e-05 1.2e-06 1.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.51.10.20.2-0.5-0.7-0.3-0.7-0.9-1.0-1.1
Area under the delay curve0.20.30.70.00.2-0.3-0.5-0.6-0.7-0.7-0.9-0.3
BMI with tail3.511.920.12.02.0-3.0-3.6-3.1-3.6-3.9-4.4-4.5
BMI without tail0.92.94.21.11.4-1.5-1.8-1.5-1.9-1.8-2.0-1.9
Body weight4.017.523.23.23.3-4.0-4.6-4.4-4.5-4.6-4.8-3.9
Weight adjusted by age0.81.21.61.31.1-1.3-1.1-1.1-1.0-0.9-1.0-1.1
Bone surface1.62.94.61.21.1-1.6-1.9-1.6-1.8-2.1-2.1-1.7
Bone volume0.61.12.10.50.3-0.8-1.1-0.6-1.0-1.3-1.4-1.4
Breakpoint value in progressive ratio session2.02.44.42.12.0-1.8-1.7-1.6-1.4-1.2-1.10.1
Number of licking bursts0.00.00.0-0.1-0.00.00.00.1-0.0-0.10.1-0.1
Context. condit. distance diff. score0.10.10.3-0.3-0.20.20.00.00.10.1-0.3-0.6
Locomotion velocity, session 10.10.10.20.20.2-0.3-0.2-0.2-0.3-0.2-0.5-0.1
Locomotion distance, session 11.01.22.11.01.0-1.2-1.1-1.0-1.2-1.1-1.5-0.8
Locomotion velocity, session 23.03.54.31.81.8-2.0-1.9-2.1-2.0-2.0-1.9-1.3
Locomotion distance, session 20.60.81.10.91.1-1.0-0.8-1.0-1.0-0.8-0.9-0.2
Locomotion velocity, session 31.21.35.10.10.2-0.6-0.9-0.7-1.1-1.3-1.5-2.3
Locomotion distance, session 30.00.00.1-0.1-0.10.0-0.10.0-0.2-0.2-0.2-0.3
Stereotopy head waving bouts, day 30.50.52.3-0.3-0.1-0.2-0.4-0.4-0.7-0.7-1.1-1.5
Stereotopy head waving duration, day 30.30.41.1-0.00.2-0.3-0.4-0.5-0.7-0.6-0.8-1.0
Locomotion velocity, session 70.10.10.3-0.00.0-0.1-0.3-0.2-0.4-0.4-0.6-0.3
Locomotion distance, session 70.10.10.4-0.20.0-0.0-0.2-0.1-0.3-0.3-0.6-0.3
Stereotopy head waving bouts, day 70.20.20.40.30.2-0.5-0.5-0.4-0.5-0.6-0.6-0.7
Stereotopy head waving duration, day 71.41.72.21.31.2-1.4-1.5-1.3-1.4-1.4-1.4-0.8
Locomotion velocity, session 80.10.10.40.30.5-0.2-0.2-0.3-0.20.0-0.10.6
Locomotion distance, session 80.10.10.3-0.3-0.20.1-0.0-0.1-0.1-0.1-0.6-0.6
Degree of sensitization distance0.30.31.1-0.1-0.0-0.3-0.4-0.4-0.5-0.6-1.0-1.0
Degree of sensitization stereotypy0.80.91.11.00.8-1.0-1.0-1.0-0.9-1.0-0.9-0.8
Conditioned locomotion0.60.60.80.80.9-0.9-0.8-0.9-0.9-0.8-0.70.1
Cocaine response after cond. corrected0.10.20.3-0.5-0.40.40.40.30.30.50.2-0.5
Cocaine response after cond. not corrected0.20.30.4-0.6-0.60.50.60.60.50.50.2-0.6
Cocaine response before conditioning0.00.00.20.3-0.2-0.20.10.40.2-0.10.10.0
Saline control response2.43.14.22.12.0-2.0-1.9-1.8-1.8-1.7-1.70.2
Bone: connectivity density1.62.54.11.21.2-1.5-1.7-1.4-1.7-1.8-2.0-1.5
Bone: cortical apparent density0.20.30.70.90.8-0.6-0.4-0.3-0.3-0.20.10.4
Bone: cortical area0.40.60.90.70.6-0.8-0.9-0.6-0.8-1.0-0.9-0.4
Bone: cortical porosity0.20.20.90.50.6-0.2-0.1-0.40.10.30.51.0
Bone: cortical porosity0.30.30.70.70.8-0.4-0.4-0.6-0.20.00.10.8
Bone: cortical thickness2.23.76.52.52.5-2.2-2.1-2.1-1.8-1.5-1.10.5
Bone: cortical thickness0.20.20.50.70.7-0.5-0.4-0.3-0.4-0.2-0.00.4
Bone: cortical tissue density0.30.41.11.11.0-0.8-0.6-0.5-0.5-0.4-0.10.4
Condit. Reinf. active minus inactive responses0.80.91.31.11.0-1.2-0.9-0.7-0.9-0.9-0.8-0.9
Condit. Reinf. active-inactive response ratio0.30.40.91.00.9-0.8-0.5-0.5-0.5-0.3-0.2-0.2
Condit. Reinf. active responses0.80.91.90.90.7-1.1-0.9-0.6-1.0-1.0-1.1-1.4
Condit. Reinf. inactive responses0.20.31.4-0.4-0.60.10.10.30.0-0.3-0.5-1.2
Incentive salience index mean1.01.22.00.90.8-1.2-1.1-0.9-1.1-1.2-1.3-1.4
Condit. Reinf. lever presses0.70.92.20.40.3-0.8-0.9-0.7-0.9-1.2-1.3-1.5
Condit. Reinf. active minus inactive responses0.20.30.6-0.3-0.50.40.70.80.60.50.70.1
Condit. Reinf. active-inactive response ratio0.30.40.8-0.7-0.90.50.70.70.50.30.4-0.7
Condit. Reinf. active responses0.00.00.10.20.0-0.20.10.20.0-0.10.1-0.1
Condit. Reinf. inactive responses0.00.00.10.30.3-0.2-0.10.1-0.1-0.00.00.3
Condit. Reinf. lever presses0.50.61.40.70.4-0.8-0.7-0.6-0.7-1.0-0.8-1.2
Condit. Reinf. lever reinforcers received0.00.10.20.50.3-0.4-0.10.0-0.1-0.20.1-0.1
Conditioned reinforcement - actives0.20.40.7-0.3-0.50.40.80.90.70.60.7-0.2
Conditioned reinforcement - inactives0.20.31.8-0.4-0.70.20.20.10.2-0.2-0.3-1.4
Conditioned locomotion1.31.73.2-1.7-1.81.41.31.51.00.70.8-1.1
Patch foraging indifference point 0 sec0.50.81.40.90.9-0.9-1.2-1.0-0.9-0.9-1.0-0.2
Patch foraging indifference point AUC0.71.01.81.41.2-1.2-1.0-1.0-0.9-0.9-0.50.4
Delay disc. indifference point, 0s delay0.20.30.9-0.7-0.50.20.10.0-0.3-0.4-0.6-0.9
Delay disc. indifference point, 16s delay0.10.10.30.10.0-0.2-0.3-0.3-0.3-0.4-0.6-0.4
Delay disc. indifference point, 2s delay0.30.30.8-0.9-0.90.50.30.50.1-0.2-0.2-0.8
Delay disc. indifference point, 24s delay0.10.10.30.10.3-0.3-0.4-0.2-0.5-0.5-0.5-0.2
Delay disc. indifference point, 4s delay0.80.91.70.30.6-0.7-1.0-1.1-1.2-1.2-1.3-0.3
Delay disc. indifference point, 8s delay0.10.10.6-0.4-0.20.40.1-0.10.00.10.00.7
Indifference point function ln k1.83.15.8-2.4-2.22.11.81.71.71.51.1-0.7
Indifference point function log k1.83.15.8-2.4-2.22.11.81.71.71.51.1-0.7
Patch foraging total patch changes 0 sec0.40.81.30.91.0-0.9-1.1-1.0-0.9-0.7-0.9-0.0
Patch foraging total patch changes 12 sec5.36.910.23.23.2-3.0-2.9-2.8-2.6-2.4-2.1-0.1
Patch foraging total patch changes 18 sec0.40.51.11.01.0-0.9-0.7-0.7-0.7-0.5-0.20.5
Patch foraging total patch changes 24 sec4.37.49.52.82.8-2.9-3.1-2.9-2.9-2.8-2.8-0.7
Patch foraging total patch changes 6 sec1.01.52.11.21.2-1.2-1.5-1.3-1.3-1.3-1.3-0.4
Patch foraging time to switch 0 sec0.30.61.50.40.3-0.7-0.6-0.4-0.8-1.0-1.0-1.2
Patch foraging water rate 0 sec0.51.01.6-0.8-0.81.01.00.91.11.21.21.0
Patch foraging water rate 12 sec0.92.02.7-1.6-1.41.61.51.21.51.61.30.5
Patch foraging water rate 18 sec0.20.30.8-0.9-0.70.80.40.50.50.60.00.3
Patch foraging water rate 24 sec1.11.52.1-1.3-1.21.41.31.11.41.41.20.8
Patch foraging water rate 6 sec0.81.21.8-1.2-1.01.31.10.81.21.31.10.8
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.0-0.0-0.2-0.2-0.2-0.4-0.5-0.4-0.8
Distance traveled before self-admin1.21.52.31.21.0-1.4-1.2-1.0-1.3-1.5-1.3-0.9
Distance traveled after self-admin0.20.30.60.80.7-0.7-0.3-0.5-0.4-0.4-0.20.2
Extensor digitorum longus weight5.923.427.04.84.7-5.1-5.2-5.2-5.2-5.0-4.9-3.0
Bone: elastic displacement0.40.51.7-0.10.00.50.50.40.60.91.01.3
Bone: elastic work0.91.22.31.31.5-1.2-1.2-1.1-1.0-0.7-0.70.4
Bone: endosteal estimation1.02.35.1-2.2-2.21.61.21.61.00.5-0.1-1.7
Bone: endosteal perimeter1.73.68.3-2.7-2.92.11.72.11.50.80.3-1.4
Epididymis fat weight0.72.65.9-2.3-2.41.71.31.51.20.70.3-1.8
Delta time in closed arm before/after self-admin2.92.74.81.61.9-1.6-1.8-2.2-1.7-1.3-1.7-0.6
Delta time in open arm before/after self-admin1.01.01.71.31.0-1.2-1.0-0.9-0.9-1.0-0.9-0.3
Diff in mean of infusions in LGA sessions2.42.94.22.02.1-1.9-1.9-2.0-1.7-1.5-1.4-0.5
Delay discount exponential model param0.30.30.7-0.0-0.20.30.60.60.70.80.90.3
Extinction: sum of active levers before priming3.23.64.31.91.8-2.0-2.1-2.1-1.9-1.9-2.0-1.0
Active lever presses in extinction session 61.61.62.71.61.3-1.5-1.3-1.2-1.1-1.2-1.2-0.2
Bone: final force1.11.72.61.21.0-1.3-1.4-1.1-1.4-1.5-1.6-1.0
Bone: final moment1.11.72.61.21.1-1.4-1.4-1.1-1.4-1.5-1.6-0.9
Food consumed during 24 hour testing period0.30.40.7-0.5-0.60.60.80.50.80.80.80.0
Glucose1.82.85.9-2.4-2.31.91.81.81.41.20.7-0.5
Heart weight0.40.73.2-1.0-0.70.4-0.10.2-0.3-0.5-0.9-1.8
Delay discount hyperbolic model param0.20.20.60.1-0.00.20.40.40.60.70.80.4
Intermittent access intake day 1-15 change1.22.43.4-1.4-1.71.51.81.81.71.41.70.9
Intermittent access intake escalation1.42.94.1-1.6-1.81.72.01.81.91.61.90.8
Intermittent access intake escalation 20.70.81.3-0.8-1.00.81.11.11.00.81.00.5
Intermitt. access day 1 inactive lever presses0.20.81.1-0.9-1.00.91.10.81.00.91.0-0.7
Intermitt. access day 15 inactive lever presses0.81.67.00.3-0.0-0.9-0.8-0.7-1.1-1.6-1.3-2.6
Intermitt. access escalation Index0.40.50.9-0.9-0.80.90.70.60.70.70.70.2
Intermittent access day 1 total infusions0.71.14.6-1.2-1.30.3-0.1-0.0-0.3-0.9-1.0-2.1
Intermittent access day 15 total infusions2.33.47.6-2.5-2.82.01.91.91.61.01.2-0.6
Intermittent access terminal intake (last 3 days)0.81.13.5-1.6-1.90.90.80.90.6-0.0-0.0-1.2
Intermittent access total infusions0.91.03.1-1.6-1.80.90.70.70.4-0.2-0.2-1.3
Intermittent access day 1 locomotion0.60.84.1-0.5-0.6-0.1-0.5-0.3-0.5-0.9-1.0-2.0
Intermittent access day 15 total locomotion0.30.62.8-0.7-1.00.10.00.1-0.1-0.7-0.6-1.7
Intermittent access total locomotion1.31.67.9-1.2-1.50.20.00.2-0.3-1.0-1.0-2.8
Intermittent access standard deviation0.30.71.0-0.7-0.90.80.90.71.00.90.90.5
Left kidney weight0.20.92.9-1.3-1.30.70.20.50.2-0.3-0.5-1.7
Right kidney weight0.10.41.0-1.0-1.00.50.10.20.1-0.2-0.3-1.0
Cocaine induced anxiety0.10.10.40.30.2-0.20.00.00.10.10.20.7
Post-drug Anxiety0.20.20.30.50.4-0.6-0.3-0.2-0.5-0.6-0.5-0.2
Baseline Anxiety0.40.50.80.40.5-0.6-0.7-0.5-0.9-0.9-0.9-0.8
Tail length0.31.22.51.41.6-1.1-1.1-1.3-1.0-0.6-0.40.8
Length with tail1.25.27.42.42.4-2.4-2.5-2.7-2.4-2.3-2.1-0.8
Length without tail2.89.012.82.82.9-3.1-3.4-3.6-3.2-3.1-3.0-1.7
Times rat made contact with spout0.20.20.60.70.8-0.5-0.3-0.4-0.3-0.00.10.5
Lifetime Intake0.50.71.9-1.3-1.40.70.40.40.2-0.2-0.2-1.2
Liver weight, left0.91.51.8-1.2-1.11.31.31.21.31.31.20.9
Liver weight, right1.01.83.4-1.8-1.71.61.41.31.31.20.8-0.1
Locomotor activity0.40.61.1-0.7-0.40.90.60.70.71.00.71.1
Locomotor testing distance0.30.60.9-0.9-0.70.90.70.90.70.90.70.5
Locomotor testing rearing0.51.01.6-1.0-0.91.11.01.11.11.30.90.5
Locomotion in novel chamber1.41.73.2-1.7-1.81.51.41.31.31.01.00.3
Locomotion in novel chamber post-restriction1.22.02.7-1.3-1.31.51.51.41.61.61.60.9
Fecal boli incidents, locomotor time 10.40.50.9-0.5-0.80.60.70.90.80.70.80.5
Change in fecal boli incidents, locomotor task0.70.71.6-1.3-1.01.00.70.80.50.50.5-0.7
Time >=10cm from walls, locomotor time 11.92.03.9-1.7-2.01.51.41.51.51.11.0-0.3
Bouts of movement, locomotor time 10.80.93.91.31.1-0.6-0.3-0.70.10.40.72.0
Total resting periods, locomotor time 10.60.73.21.10.9-0.5-0.3-0.50.10.30.61.8
Rest time, locomotor task time 11.82.23.0-1.3-1.41.51.51.51.61.51.71.2
Distance moved, locomotor task time 10.40.51.30.40.4-0.6-0.5-0.6-0.7-0.8-0.9-1.2
Vertical activity count, locomotor time 10.10.30.6-0.7-0.70.70.60.40.60.60.3-0.1
Time >=10cm from walls, locomotor time 20.30.51.2-0.4-0.60.50.81.10.80.70.80.3
Bouts of movement, locomotor time 20.81.32.41.61.4-1.4-1.2-1.3-0.9-0.8-0.8-0.7
Total resting periods, locomotor time 20.40.81.41.21.0-1.0-0.9-1.1-0.6-0.5-0.5-0.7
Rest time, locomotor task time 21.92.42.9-1.6-1.61.71.61.21.71.71.70.9
Distance moved, locomotor task time 20.20.20.60.80.7-0.6-0.4-0.4-0.4-0.3-0.20.2
Vertical activity count, locomotor time 20.20.21.10.10.30.20.10.00.30.50.51.1
Light reinforcement 10.10.30.8-0.4-0.50.40.60.90.50.40.60.1
Light reinforcement 20.50.71.7-1.0-1.30.80.71.00.60.20.1-1.0
Bone: marrow area1.22.65.6-2.3-2.41.71.41.71.10.60.0-1.6
Bone: maximum diameter0.10.20.8-0.1-0.3-0.2-0.30.0-0.3-0.6-0.7-0.9
Bone: maximum force1.93.35.91.31.1-1.7-1.9-1.5-1.9-2.2-2.4-1.9
Bone: maximum moment1.93.35.61.31.2-1.7-1.9-1.5-1.9-2.2-2.4-1.8
Mean time between licks in bursts0.20.61.50.70.9-0.7-0.8-1.2-0.8-0.5-0.6-0.3
Mean num. licks in bursts0.10.10.40.30.3-0.00.1-0.10.20.50.40.6
Cd content in liver0.70.81.0-0.9-1.00.91.00.90.90.80.80.5
Co content in liver0.91.02.2-0.5-0.40.90.90.71.01.21.31.5
Cu content in liver0.00.00.10.10.20.00.1-0.20.00.10.20.0
Fe content in liver0.00.00.0-0.1-0.00.00.0-0.1-0.1-0.0-0.1-0.1
K content in liver0.40.30.80.30.2-0.5-0.5-0.6-0.6-0.8-0.9-0.5
Mg content in liver0.10.10.5-0.2-0.1-0.1-0.3-0.4-0.3-0.4-0.7-0.3
Mn content in liver2.42.73.31.71.6-1.8-1.7-1.8-1.7-1.8-1.6-0.9
Na content in liver0.10.10.30.30.1-0.4-0.4-0.2-0.3-0.4-0.5-0.1
Rb content in liver2.02.33.0-1.7-1.61.71.61.51.51.61.31.0
Se content in liver0.10.10.70.20.1-0.3-0.2-0.3-0.2-0.4-0.3-0.8
Sr content in liver4.53.95.22.32.3-2.2-2.1-2.2-2.0-1.8-1.6-0.9
Zn content in liver3.13.54.91.92.0-2.0-2.0-2.2-2.0-1.8-1.8-0.4
Bone: minimum diameter0.71.33.4-1.7-1.81.20.91.20.70.2-0.2-1.3
Time in familiar zone, hab. session 10.00.00.20.0-0.1-0.1-0.10.0-0.0-0.1-0.4-0.4
Time in novel zone, hab. session 11.41.41.6-1.1-1.11.21.31.21.21.21.30.9
Total zone transitions, hab. session 10.30.40.70.80.9-0.7-0.7-0.6-0.6-0.4-0.50.6
Total locomotion distance, hab. session 10.00.10.2-0.2-0.2-0.0-0.10.0-0.1-0.2-0.5-0.4
Locomotion velocity, hab. session 10.30.40.70.50.5-0.7-0.7-0.6-0.7-0.7-0.8-0.3
Time in familiar zone, hab. session 20.91.01.4-0.7-0.70.91.00.91.11.11.21.2
Time in novel zone, hab. session 21.01.01.70.70.8-0.9-1.1-0.9-1.1-1.1-1.3-1.1
Total zone transitions, hab. session 21.01.32.21.11.1-1.2-1.3-1.0-1.2-1.2-1.5-0.3
Total locomotion distance, hab. session 20.20.20.80.20.2-0.4-0.5-0.3-0.5-0.5-0.9-0.5
Locomotion velocity, hab. session 20.10.20.70.00.0-0.3-0.3-0.2-0.4-0.5-0.8-0.6
Novel to familiar place preference ratio2.32.63.21.41.6-1.6-1.7-1.8-1.8-1.7-1.7-0.9
Novelty place preference1.51.62.01.11.2-1.2-1.4-1.4-1.4-1.4-1.4-0.8
Time in novel zone, NPP test1.71.82.31.21.3-1.3-1.5-1.5-1.5-1.4-1.5-1.0
Total zone transitions, NPP test1.21.72.51.51.6-1.5-1.4-1.2-1.3-1.1-1.20.3
Total locomotion distance, NPP test0.20.30.50.50.6-0.5-0.6-0.5-0.6-0.5-0.70.3
Locomotion velocity, NPP test0.20.20.60.40.5-0.4-0.4-0.5-0.4-0.3-0.50.7
Intraocular pressure0.20.30.7-0.1-0.10.30.60.30.60.70.80.5
Delta distance traveled before/after self-admin0.30.40.8-0.3-0.10.60.60.20.60.90.70.9
Delta ambulatory time before/after self-admin0.50.61.2-0.5-0.20.70.80.50.81.11.00.8
Parametrial fat weight1.33.27.5-2.7-2.72.01.41.91.30.60.4-1.4
Pavlov. Cond. lever latency0.70.91.5-0.7-0.60.91.00.90.91.11.21.1
Pavlov. Cond. magazine entry latency0.60.81.60.70.4-0.9-0.8-0.7-0.8-1.1-1.1-1.3
Pavlov. Cond. change in total contacts0.20.20.60.40.1-0.5-0.3-0.4-0.3-0.5-0.5-0.8
Pavlov. Cond. index score0.30.40.50.60.4-0.7-0.6-0.7-0.6-0.7-0.7-0.7
Pavlov. Cond. latency score0.30.40.70.50.3-0.6-0.6-0.6-0.5-0.7-0.8-0.8
Pavlov. Cond. lever contacts0.30.40.80.30.2-0.5-0.6-0.5-0.6-0.7-0.9-0.8
Pavlov. Cond. magazine entry number0.40.50.8-0.9-0.60.80.60.80.60.70.50.5
Pavlov. Cond. intertrial magazine entries0.20.31.70.40.4-0.2-0.10.20.00.10.41.3
Pavlov. Cond. lever-magazine prob. diff.0.40.50.60.70.5-0.8-0.7-0.7-0.6-0.8-0.7-0.7
Pavlov. Cond. response bias0.50.60.80.80.6-0.9-0.8-0.8-0.7-0.9-0.8-0.8
Pavlov. Cond. lever latency0.40.51.5-0.5-0.20.70.50.60.60.80.71.2
Pavlov. Cond. magazine entry latency4.04.96.72.52.1-2.6-2.2-2.3-2.1-2.2-1.9-1.8
Pavlov. Cond. change in total contacts0.50.91.71.00.5-1.1-0.8-0.8-0.7-1.1-0.8-1.3
Pavlov. Cond. index score1.92.53.91.71.2-1.8-1.4-1.4-1.4-1.7-1.5-2.0
Pavlov. Cond. latency score1.82.43.81.61.1-1.8-1.4-1.4-1.4-1.7-1.5-1.9
Pavlov. Cond. lever contacts0.30.41.40.50.2-0.6-0.4-0.5-0.4-0.6-0.4-1.2
Pavlov. Cond. magazine entry number6.17.510.2-3.1-2.73.22.72.72.72.82.42.2
Pavlov. Cond. intertrial magazine entries1.42.13.4-1.4-1.31.51.51.81.41.41.51.2
Pavlov. Cond. lever-magazine prob. diff.2.12.84.01.81.3-1.9-1.5-1.5-1.5-1.8-1.5-2.0
Pavlov. Cond. response bias1.52.03.21.41.0-1.6-1.3-1.5-1.3-1.5-1.3-1.8
Time in closed arm before self-admin0.20.30.7-0.6-0.80.40.50.70.40.10.2-0.3
Time in closed arm after self-admin0.30.40.6-0.8-0.70.70.70.60.50.60.4-0.1
Time in open arm before self-admin0.40.41.5-0.6-0.10.70.50.20.40.80.71.2
Time in open arm after self-admin0.50.51.00.91.0-0.7-0.7-0.8-0.5-0.3-0.20.9
Bone: periosteal estimation0.30.51.9-0.9-1.00.40.10.60.1-0.4-0.7-1.4
Bone: periosteal perimeter0.20.30.7-0.6-0.80.30.10.50.2-0.2-0.4-0.8
Bone: post-yield work0.60.93.1-1.2-1.40.60.20.60.1-0.6-0.9-1.8
Progressive ratio test 1 active lever presses0.10.10.4-0.5-0.60.30.30.20.2-0.00.1-0.3
Progressive ratio test 1 breakpoint0.10.10.4-0.5-0.60.30.30.20.20.00.1-0.3
Progressive ratio test 1 inactive lever presses1.21.72.90.90.7-1.2-1.3-1.5-1.3-1.5-1.4-1.7
Progressive ratio test 2 active lever presses0.60.72.0-1.2-1.40.80.80.80.60.20.2-0.9
Progressive ratio test 2 breakpoint0.60.72.0-1.2-1.40.80.80.70.50.10.2-1.0
Progressive ratio test 2 inactive lever presses0.50.72.8-1.0-1.30.60.50.60.3-0.1-0.1-1.7
Incentive Sensitization - Responses0.60.82.60.20.0-0.6-0.6-0.6-0.8-1.1-1.2-1.6
Incentive Sensitization - Breakpoint0.50.72.70.0-0.2-0.5-0.5-0.5-0.7-1.1-1.1-1.7
Sum of active levers in priming session hrs 5-60.30.31.11.00.7-0.7-0.4-0.5-0.2-0.20.10.0
Progressive ratio0.10.10.4-0.5-0.60.1-0.0-0.2-0.0-0.3-0.4-0.3
Food seeking constrained by brief footshock0.10.10.4-0.2-0.20.20.20.60.10.1-0.0-0.4
Seeking ratio, punishment vs. effort0.10.10.30.20.5-0.2-0.10.3-0.30.0-0.1-0.5
Retroperitoneal fat weight2.510.520.1-4.5-4.33.93.23.23.12.52.0-0.5
Reaction time number correct0.10.30.40.60.7-0.5-0.6-0.6-0.4-0.3-0.40.2
Reaction time mean minus median0.10.31.01.00.8-0.7-0.5-0.6-0.3-0.3-0.1-0.0
Reaction time mean minus median AUC0.10.20.60.80.7-0.4-0.1-0.10.20.30.50.7
Reaction time num false alarms0.20.31.5-0.20.10.30.30.00.20.50.51.2
Reaction time num false alarms AUC0.20.31.50.40.8-0.2-0.3-0.5-0.30.10.21.2
Reaction time trials correct on left0.10.30.40.60.7-0.5-0.6-0.6-0.4-0.3-0.40.2
Reaction time trials on left0.20.30.50.70.7-0.6-0.6-0.7-0.4-0.3-0.40.3
Reaction time mean0.10.10.30.2-0.10.00.30.10.50.40.50.0
Reaction time mean AUC0.20.20.5-0.1-0.40.30.60.40.70.60.7-0.1
Median of all reaction times0.00.00.10.1-0.20.00.20.10.40.20.3-0.3
Reaction time omissions0.20.30.80.90.8-0.6-0.5-0.7-0.3-0.2-0.00.3
Reaction time false alarm rate0.10.10.6-0.10.10.20.1-0.00.00.20.30.8
Reaction time premature initiation rate4.15.77.81.91.9-2.3-2.5-2.3-2.7-2.8-2.7-2.1
Reaction time premature initiations3.56.27.52.42.4-2.6-2.7-2.6-2.7-2.7-2.6-1.5
Std. dev. reaction times0.10.20.70.30.20.10.30.10.60.70.80.7
Reaction time trials completed0.20.30.50.70.7-0.6-0.6-0.7-0.4-0.3-0.40.3
Reaction time trials AUC0.10.20.30.60.6-0.5-0.6-0.6-0.4-0.2-0.40.2
Run reversals in cocaine runway, females0.80.81.70.20.3-0.6-1.0-0.7-1.0-1.1-1.3-1.2
Run reversals in cocaine runway, males0.60.61.5-0.7-0.60.80.60.60.70.80.81.2
Latency to leave start box in cocaine runway0.50.51.4-1.2-1.20.70.40.60.3-0.0-0.1-0.9
Latency to leave start box in cocaine runway, F0.10.20.6-0.2-0.2-0.1-0.4-0.1-0.4-0.5-0.5-0.8
Latency to leave start box in cocaine runway, M2.01.93.1-1.8-1.71.61.41.51.31.10.90.0
Std. dev. time between licks in bursts0.10.10.2-0.4-0.30.40.2-0.20.20.30.1-0.4
Total sessions with >9 infusions0.30.30.8-0.7-0.80.60.50.30.50.40.3-0.9
Short access day 1 total inactive lever presses0.10.10.4-0.3-0.20.1-0.2-0.2-0.2-0.3-0.4-0.6
Short access day 10 total inactive lever presses0.20.41.0-0.5-0.40.70.70.30.81.00.80.3
Short access day 1 total infusions0.60.71.4-1.2-1.21.00.80.70.80.70.6-0.3
Short access day 10 total infusions0.40.51.5-0.9-1.00.2-0.0-0.0-0.2-0.6-0.7-1.2
Short access total infusions0.30.41.2-0.9-0.90.40.20.00.0-0.2-0.3-1.1
Short access day 1 locomotion0.10.10.5-0.4-0.40.30.20.10.30.20.1-0.7
Short access day 10 total locomotion0.50.85.4-0.4-0.5-0.2-0.3-0.2-0.5-0.8-0.9-2.3
Short access total locomotion0.50.63.8-0.5-0.60.0-0.1-0.1-0.2-0.5-0.5-2.0
One hour access (0.3 mA shock)0.91.02.6-1.4-1.61.00.90.90.70.20.3-1.0
Compulsive drug intake0.60.72.11.21.4-0.9-0.7-0.9-0.6-0.2-0.20.1
One hour access (shock baseline)2.03.17.0-2.4-2.61.91.81.91.61.01.1-0.1
Social response proportion0.00.00.2-0.00.00.0-0.0-0.1-0.1-0.2-0.10.5
Social responses0.20.31.90.30.4-0.00.1-0.20.10.30.51.4
Social time0.30.42.20.50.6-0.10.1-0.20.20.50.51.5
Soleus weight2.88.210.2-2.9-2.93.13.13.23.02.92.71.5
Bone: stiffness0.20.30.60.40.2-0.5-0.6-0.4-0.5-0.8-0.8-0.8
Tibialis anterior weight8.428.535.05.95.9-5.9-5.8-5.9-5.6-5.2-4.8-1.7
Time to tail flick, vehicle, before self-admin0.60.62.60.00.0-0.4-0.5-0.5-0.6-0.8-0.9-1.6
Time to tail flick, vehicle, after self-admin0.70.91.60.50.6-0.8-0.9-1.0-1.0-1.0-1.1-1.2
Time to tail flick, test, before self-admin0.60.61.5-0.00.2-0.4-0.8-0.6-0.9-1.0-1.2-0.7
Time to tail flick, test, after self-admin0.10.10.30.1-0.10.10.30.40.20.20.40.6
Delta time to tail flick, vehicle, before/after SA0.30.30.50.70.7-0.6-0.6-0.6-0.6-0.4-0.50.1
Delta time to tail flick, test, before/after SA0.50.51.70.50.20.00.60.40.70.81.21.3
Tibia length1.02.83.81.71.4-1.8-1.8-1.7-1.7-1.9-1.7-1.1
Ambulatory time before self-admin0.71.01.61.10.7-1.2-1.0-0.7-1.0-1.3-1.1-0.6
Ambulatory time after self-admin0.10.10.20.20.0-0.3-0.00.0-0.2-0.4-0.2-0.5
Bone: tissue strength0.70.70.9-0.9-0.80.90.91.00.90.90.80.3
Total heroin consumption4.85.710.03.23.1-2.7-2.5-2.6-2.2-1.8-1.70.2
Bone: trabecular number1.01.62.80.80.7-1.1-1.3-0.9-1.3-1.5-1.7-1.6
Bone: trabecular spacing0.81.02.3-0.4-0.30.70.90.91.01.31.31.5
Bone: trabecular thickness0.30.40.8-0.7-0.80.70.50.90.60.40.4-0.2
Bone: trabecular tissue density4.36.48.0-2.4-2.32.72.82.72.72.72.81.5
Water consumed over 24 hours0.30.40.80.90.9-0.7-0.6-0.7-0.6-0.5-0.3-0.3
Number of responses in last shaping day0.70.81.61.01.2-0.9-0.9-1.2-0.8-0.6-0.7-0.1