Hub : Genes

Pitpnm1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Pitpnm1 0.27 0.09 5.0e-12 0.06 0.1 0.09 0.08 3.9e-07 6.0e-11 2.6e-10 7.9e-09
2 NAcc gene expression Pitpnm1 0.02 0.02 6.9e-03 0.01 0.02 0.01 0.02 1.2e-02 2.0e-03 9.1e-03 3.4e-03
3 Liver mRNA stability Pitpnm1 0.02 0.02 8.9e-03 0 0.01 0 0 8.8e-02 5.0e-02 1.3e-01 1.4e-01
4 Adipose isoform ratio NM_001008369.1 0.03 0.02 7.5e-03 0.01 0.01 0 0 3.5e-02 1.4e-02 2.8e-01 9.3e-02
5 Liver gene expression Pitpnm1 0.24 0.11 0.0e+00 0.18 0.19 0.19 0.19 8.3e-20 5.9e-21 2.2e-20 3.1e-20
6 PL gene expression Pitpnm1 0.03 0.03 1.7e-03 0.01 0.02 0.02 0.02 8.8e-03 9.2e-04 1.9e-03 3.7e-03
7 Brain gene expression Pitpnm1 0.21 0.14 1.3e-10 0.1 0.08 0.14 0.09 5.7e-10 1.2e-07 6.7e-13 5.3e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density1.42.45.30.60.6-1.41.5-1.72.3-1.9
Area under the delay curve0.91.01.50.70.7-1.01.0-1.11.2-0.9
BMI with tail0.62.06.6-1.1-1.1-0.30.4-0.72.1-2.6
BMI without tail0.40.72.4-0.8-0.7-0.10.1-0.31.2-1.6
Body weight1.35.412.1-3.5-3.42.3-2.11.8-0.2-1.1
Weight adjusted by age0.80.91.9-1.4-1.31.0-1.00.9-0.3-0.1
Bone surface0.71.23.7-0.7-0.6-0.50.6-0.81.9-1.7
Bone volume0.81.43.90.30.3-1.11.2-1.32.0-1.3
Breakpoint value in progressive ratio session0.80.92.1-1.5-1.41.0-0.90.8-0.10.0
Number of licking bursts0.00.10.10.20.1-0.20.3-0.30.4-0.0
Context. condit. distance diff. score0.91.01.71.31.3-1.11.1-1.00.70.1
Locomotion velocity, session 10.00.00.00.0-0.0-0.00.0-0.00.10.0
Locomotion distance, session 10.60.82.10.10.1-0.70.8-0.91.4-1.2
Locomotion velocity, session 21.31.52.8-1.7-1.71.3-1.21.1-0.5-0.1
Locomotion distance, session 20.20.30.6-0.6-0.60.1-0.1-0.00.6-0.7
Locomotion velocity, session 31.21.42.40.70.7-1.11.2-1.31.5-1.4
Locomotion distance, session 30.10.10.20.20.1-0.30.3-0.30.4-0.4
Stereotopy head waving bouts, day 31.72.02.51.21.2-1.51.5-1.51.6-1.4
Stereotopy head waving duration, day 31.72.02.41.61.5-1.51.5-1.51.3-0.9
Locomotion velocity, session 70.91.01.70.70.6-1.01.0-1.11.3-1.2
Locomotion distance, session 70.10.10.5-0.4-0.30.1-0.10.00.3-0.7
Stereotopy head waving bouts, day 71.82.12.41.41.3-1.51.6-1.61.5-1.2
Stereotopy head waving duration, day 70.70.92.00.10.1-0.70.8-0.91.4-1.4
Locomotion velocity, session 80.60.81.6-1.2-1.30.9-0.90.8-0.2-0.2
Locomotion distance, session 80.40.60.80.80.8-0.90.9-0.90.8-0.2
Degree of sensitization distance0.20.20.7-0.2-0.2-0.10.1-0.20.5-0.8
Degree of sensitization stereotypy0.30.30.80.20.2-0.50.5-0.60.9-0.7
Conditioned locomotion4.14.85.8-2.3-2.32.4-2.42.4-2.01.4
Cocaine response after cond. corrected0.20.20.30.50.5-0.50.5-0.40.3-0.2
Cocaine response after cond. not corrected0.50.60.70.70.7-0.80.8-0.80.8-0.6
Cocaine response before conditioning0.10.10.30.00.0-0.20.2-0.30.4-0.5
Saline control response1.11.53.2-1.8-1.71.2-1.21.0-0.3-0.2
Bone: connectivity density1.01.65.1-0.5-0.4-0.60.7-1.02.0-2.2
Bone: cortical apparent density0.50.71.1-1.0-1.00.9-0.90.9-0.6-0.3
Bone: cortical area0.91.31.5-1.1-1.11.2-1.21.2-1.11.0
Bone: cortical porosity0.00.10.10.20.2-0.20.3-0.30.3-0.2
Bone: cortical porosity0.10.10.3-0.5-0.50.3-0.30.3-0.1-0.1
Bone: cortical thickness5.69.111.3-3.3-3.43.3-3.33.2-2.61.5
Bone: cortical thickness2.32.73.7-1.9-1.91.8-1.81.7-1.20.7
Bone: cortical tissue density0.70.91.3-1.1-1.21.0-1.01.0-0.7-0.3
Condit. Reinf. active minus inactive responses0.20.30.50.20.2-0.50.5-0.50.7-0.7
Condit. Reinf. active-inactive response ratio0.30.30.40.40.4-0.60.6-0.60.6-0.5
Condit. Reinf. active responses0.00.10.10.10.1-0.20.2-0.20.3-0.3
Condit. Reinf. inactive responses0.00.00.10.00.00.1-0.10.1-0.20.3
Incentive salience index mean0.10.10.30.0-0.0-0.20.3-0.30.6-0.5
Condit. Reinf. lever presses0.10.10.1-0.3-0.30.3-0.30.3-0.30.3
Condit. Reinf. active minus inactive responses2.02.52.91.51.4-1.71.7-1.71.6-1.4
Condit. Reinf. active-inactive response ratio2.32.43.41.81.8-1.71.7-1.61.2-0.7
Condit. Reinf. active responses1.62.23.21.01.0-1.51.5-1.61.8-1.7
Condit. Reinf. inactive responses0.30.41.1-0.4-0.3-0.30.3-0.41.0-1.1
Condit. Reinf. lever presses0.20.30.8-0.4-0.3-0.20.3-0.40.9-0.7
Condit. Reinf. lever reinforcers received1.31.93.10.80.8-1.31.4-1.51.8-1.7
Conditioned reinforcement - actives0.10.10.40.10.10.2-0.20.3-0.60.4
Conditioned reinforcement - inactives2.83.26.62.62.5-1.91.8-1.60.6-0.0
Conditioned locomotion2.22.66.32.52.5-1.31.2-0.9-0.61.3
Patch foraging indifference point 0 sec0.30.40.70.80.8-0.70.7-0.60.3-0.3
Patch foraging indifference point AUC1.51.82.5-1.6-1.61.4-1.41.4-1.00.7
Delay disc. indifference point, 0s delay1.51.62.50.90.9-1.31.3-1.41.6-1.4
Delay disc. indifference point, 16s delay1.31.32.31.51.4-1.21.2-1.20.8-0.2
Delay disc. indifference point, 2s delay0.90.91.10.90.9-1.01.0-1.11.0-0.8
Delay disc. indifference point, 24s delay0.30.30.4-0.5-0.50.6-0.60.6-0.60.6
Delay disc. indifference point, 4s delay0.20.20.50.20.3-0.50.5-0.60.7-0.4
Delay disc. indifference point, 8s delay0.30.30.50.30.2-0.40.5-0.50.7-0.7
Indifference point function ln k1.92.65.42.32.3-1.71.6-1.40.50.0
Indifference point function log k1.92.65.42.32.3-1.71.6-1.40.50.0
Patch foraging total patch changes 0 sec0.00.00.10.30.3-0.10.1-0.0-0.30.2
Patch foraging total patch changes 12 sec1.21.53.1-1.8-1.71.3-1.21.1-0.50.3
Patch foraging total patch changes 18 sec0.00.10.1-0.3-0.40.2-0.10.10.1-0.2
Patch foraging total patch changes 24 sec1.01.21.8-1.3-1.21.2-1.21.1-0.90.8
Patch foraging total patch changes 6 sec0.20.20.8-0.5-0.50.1-0.0-0.10.6-0.9
Patch foraging time to switch 0 sec0.71.03.2-0.2-0.3-0.60.7-0.91.8-1.4
Patch foraging water rate 0 sec0.91.54.21.11.10.2-0.30.6-1.92.0
Patch foraging water rate 12 sec1.21.95.01.61.5-0.1-0.00.4-1.82.2
Patch foraging water rate 18 sec0.30.41.00.91.0-0.40.4-0.2-0.40.7
Patch foraging water rate 24 sec0.71.02.70.50.50.4-0.50.7-1.61.6
Patch foraging water rate 6 sec0.71.03.00.30.30.5-0.60.8-1.61.7
Seeking ratio, delayed vs. immediate footshock0.50.51.00.30.4-0.70.7-0.81.0-0.9
Distance traveled before self-admin0.00.00.1-0.1-0.1-0.00.0-0.10.20.1
Distance traveled after self-admin0.00.00.20.10.1-0.10.2-0.20.2-0.4
Extensor digitorum longus weight4.015.728.7-5.4-5.34.3-4.13.8-2.00.4
Bone: elastic displacement2.02.24.2-0.8-0.71.4-1.51.6-2.01.9
Bone: elastic work2.73.54.3-2.0-2.02.1-2.12.0-1.81.0
Bone: endosteal estimation2.14.55.62.32.4-2.42.3-2.31.9-0.8
Bone: endosteal perimeter4.49.111.33.33.3-3.43.3-3.32.7-1.0
Epididymis fat weight1.84.28.42.92.8-2.22.1-1.90.80.3
Delta time in closed arm before/after self-admin1.31.21.6-1.3-1.21.2-1.21.2-0.90.6
Delta time in open arm before/after self-admin0.20.20.30.50.6-0.50.5-0.50.4-0.1
Diff in mean of infusions in LGA sessions0.50.50.6-0.7-0.80.7-0.70.7-0.50.8
Delay discount exponential model param0.60.61.1-0.5-0.50.8-0.80.9-1.00.7
Extinction: sum of active levers before priming1.11.12.6-1.6-1.50.9-0.80.60.3-0.9
Active lever presses in extinction session 62.52.42.9-1.7-1.61.6-1.71.6-1.41.1
Bone: final force0.40.71.7-1.3-1.30.8-0.70.60.1-0.1
Bone: final moment0.40.61.5-1.2-1.20.8-0.70.60.1-0.0
Food consumed during 24 hour testing period0.20.21.10.40.30.0-0.00.1-0.41.1
Glucose3.04.65.52.32.2-2.32.3-2.32.0-1.1
Heart weight1.21.72.81.71.6-1.41.3-1.20.7-0.7
Delay discount hyperbolic model param0.60.61.1-0.5-0.50.8-0.80.9-1.00.7
Intermittent access intake day 1-15 change0.50.51.01.01.0-0.50.4-0.3-0.30.9
Intermittent access intake escalation0.70.71.61.31.1-0.80.7-0.60.10.5
Intermittent access intake escalation 20.20.20.50.70.6-0.30.2-0.1-0.30.3
Intermitt. access day 1 inactive lever presses1.01.11.91.31.4-1.11.1-1.00.5-0.4
Intermitt. access day 15 inactive lever presses2.02.23.51.91.7-1.61.5-1.51.0-0.9
Intermitt. access escalation Index1.00.91.81.41.3-0.80.7-0.6-0.21.2
Intermittent access day 1 total infusions7.38.59.73.02.9-3.13.1-3.12.8-2.4
Intermittent access day 15 total infusions6.57.312.43.53.3-2.92.9-2.71.7-1.0
Intermittent access terminal intake (last 3 days)5.96.59.73.13.0-2.72.7-2.61.9-1.3
Intermittent access total infusions4.95.47.22.72.5-2.52.5-2.41.9-1.5
Intermittent access day 1 locomotion4.24.45.11.91.9-2.22.2-2.32.2-2.1
Intermittent access day 15 total locomotion3.63.96.62.62.4-2.12.1-2.01.2-0.5
Intermittent access total locomotion7.38.311.53.43.2-3.13.1-3.02.3-1.4
Intermittent access standard deviation0.40.41.01.00.9-0.60.6-0.50.10.3
Left kidney weight0.20.61.51.21.1-0.40.4-0.2-0.60.7
Right kidney weight0.20.61.90.60.60.1-0.20.4-1.21.4
Cocaine induced anxiety0.00.00.10.20.1-0.00.00.0-0.0-0.2
Post-drug Anxiety1.41.51.9-1.4-1.41.4-1.31.3-1.00.5
Baseline Anxiety2.02.23.4-1.8-1.71.6-1.61.5-1.10.7
Tail length1.44.25.2-2.3-2.12.3-2.32.2-1.90.9
Length with tail2.48.713.1-3.6-3.53.2-3.23.0-2.10.7
Length without tail1.73.86.4-2.5-2.52.1-2.11.9-1.1-0.1
Times rat made contact with spout0.10.10.4-0.3-0.3-0.10.2-0.30.7-0.3
Lifetime Intake4.14.65.92.42.3-2.32.3-2.21.8-1.5
Liver weight, left0.10.10.30.40.4-0.30.3-0.20.10.5
Liver weight, right0.20.30.7-0.2-0.20.4-0.50.5-0.80.9
Locomotor activity0.10.20.40.50.6-0.10.10.0-0.50.6
Locomotor testing distance0.20.30.70.60.8-0.30.2-0.1-0.50.8
Locomotor testing rearing0.81.31.91.31.4-1.31.2-1.20.9-0.3
Locomotion in novel chamber4.45.49.93.23.0-2.52.4-2.21.3-0.2
Locomotion in novel chamber post-restriction1.51.83.82.01.9-1.31.3-1.10.30.4
Fecal boli incidents, locomotor time 10.00.00.10.10.2-0.20.2-0.20.10.0
Change in fecal boli incidents, locomotor task0.10.10.3-0.3-0.30.1-0.0-0.00.3-0.6
Time >=10cm from walls, locomotor time 14.34.45.02.11.9-2.22.2-2.22.1-1.8
Bouts of movement, locomotor time 11.41.51.8-1.2-1.31.3-1.31.3-1.11.2
Total resting periods, locomotor time 11.01.01.4-0.9-1.01.1-1.11.1-1.01.2
Rest time, locomotor task time 10.50.62.30.70.6-0.0-0.00.2-0.81.5
Distance moved, locomotor task time 10.80.91.80.40.5-0.80.9-1.01.2-1.3
Vertical activity count, locomotor time 11.51.62.01.41.4-1.41.3-1.31.0-1.0
Time >=10cm from walls, locomotor time 20.00.00.10.20.10.0-0.10.1-0.3-0.3
Bouts of movement, locomotor time 20.40.50.8-0.9-0.90.8-0.70.7-0.4-0.1
Total resting periods, locomotor time 20.10.10.2-0.4-0.50.4-0.30.3-0.1-0.3
Rest time, locomotor task time 22.32.74.42.11.9-1.81.8-1.71.2-0.1
Distance moved, locomotor task time 21.11.31.9-1.4-1.21.2-1.21.2-1.00.5
Vertical activity count, locomotor time 22.02.23.5-1.3-1.11.5-1.61.7-1.91.2
Light reinforcement 10.20.51.40.90.8-0.40.3-0.2-0.31.2
Light reinforcement 20.81.12.41.51.5-0.90.8-0.6-0.21.0
Bone: marrow area2.14.55.62.32.4-2.42.3-2.31.9-0.8
Bone: maximum diameter0.00.10.40.30.3-0.10.0-0.0-0.20.6
Bone: maximum force0.40.82.3-0.6-0.5-0.30.4-0.61.5-1.3
Bone: maximum moment0.40.61.8-0.6-0.5-0.30.3-0.51.3-1.2
Mean time between licks in bursts0.60.91.5-1.2-1.21.0-1.00.9-0.5-0.6
Mean num. licks in bursts0.00.00.1-0.10.0-0.10.1-0.20.2-0.2
Cd content in liver0.50.51.21.11.1-0.60.6-0.4-0.20.6
Co content in liver0.50.61.6-0.2-0.20.7-0.70.8-1.11.2
Cu content in liver0.20.20.3-0.5-0.50.5-0.50.5-0.40.1
Fe content in liver0.00.00.1-0.3-0.20.2-0.20.2-0.1-0.2
K content in liver0.40.41.1-0.4-0.4-0.20.3-0.41.1-0.9
Mg content in liver2.42.54.31.01.0-1.61.7-1.82.1-1.5
Mn content in liver0.50.51.2-1.1-1.10.7-0.70.6-0.1-0.1
Na content in liver0.40.51.0-0.5-0.50.6-0.70.7-0.71.0
Rb content in liver3.54.35.12.02.0-2.22.3-2.32.1-1.7
Se content in liver0.91.11.41.00.9-1.11.1-1.21.2-0.6
Sr content in liver2.82.63.4-1.8-1.81.8-1.81.7-1.30.8
Zn content in liver0.60.61.2-1.1-1.00.8-0.80.8-0.40.1
Bone: minimum diameter2.44.45.52.02.1-2.32.3-2.32.2-1.2
Time in familiar zone, hab. session 10.70.70.90.90.9-0.90.9-0.90.7-0.6
Time in novel zone, hab. session 10.10.10.1-0.3-0.30.3-0.30.3-0.30.3
Total zone transitions, hab. session 10.10.10.3-0.6-0.50.3-0.20.10.2-0.3
Total locomotion distance, hab. session 10.50.60.91.00.9-0.90.9-0.80.6-0.4
Locomotion velocity, hab. session 10.10.20.20.50.5-0.40.4-0.40.3-0.2
Time in familiar zone, hab. session 21.21.31.6-1.2-1.21.2-1.21.2-1.10.7
Time in novel zone, hab. session 21.31.31.80.90.9-1.21.2-1.21.3-1.1
Total zone transitions, hab. session 21.41.84.50.00.0-1.01.1-1.32.1-2.0
Total locomotion distance, hab. session 21.11.52.50.80.8-1.21.2-1.31.6-1.4
Locomotion velocity, hab. session 21.31.82.51.11.0-1.41.4-1.51.6-1.3
Novel to familiar place preference ratio0.30.30.60.10.2-0.40.5-0.50.8-0.8
Novelty place preference0.50.50.80.40.4-0.70.7-0.70.9-0.8
Time in novel zone, NPP test0.50.50.80.40.4-0.70.7-0.70.9-0.8
Total zone transitions, NPP test0.30.41.2-0.6-0.5-0.10.1-0.30.9-1.1
Total locomotion distance, NPP test0.40.50.70.50.5-0.70.7-0.70.9-0.8
Locomotion velocity, NPP test0.20.30.40.50.4-0.60.6-0.60.7-0.6
Intraocular pressure0.50.72.10.00.00.5-0.60.7-1.21.4
Delta distance traveled before/after self-admin0.00.00.2-0.0-0.00.0-0.10.1-0.1-0.4
Delta ambulatory time before/after self-admin0.10.10.2-0.3-0.30.3-0.30.3-0.3-0.4
Parametrial fat weight2.03.95.62.42.3-2.22.2-2.11.6-0.7
Pavlov. Cond. lever latency0.00.00.10.30.2-0.00.00.0-0.3-0.0
Pavlov. Cond. magazine entry latency1.01.32.10.90.9-1.21.3-1.31.4-0.8
Pavlov. Cond. change in total contacts0.80.91.11.01.0-1.11.1-1.10.9-0.4
Pavlov. Cond. index score0.10.10.10.30.3-0.30.3-0.30.20.3
Pavlov. Cond. latency score0.10.10.20.40.3-0.40.4-0.40.50.1
Pavlov. Cond. lever contacts0.00.00.10.00.0-0.10.2-0.20.30.2
Pavlov. Cond. magazine entry number0.00.10.2-0.3-0.30.2-0.10.10.0-0.4
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.0-0.10.4-0.50.5-0.80.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.20.2-0.20.2-0.20.20.1
Pavlov. Cond. response bias0.10.10.10.30.3-0.30.3-0.30.20.2
Pavlov. Cond. lever latency0.00.00.10.10.10.0-0.00.1-0.2-0.2
Pavlov. Cond. magazine entry latency0.50.61.3-1.2-1.10.3-0.20.00.9-0.8
Pavlov. Cond. change in total contacts0.20.30.90.10.1-0.50.5-0.61.0-0.5
Pavlov. Cond. index score0.10.10.4-0.5-0.50.00.0-0.10.6-0.3
Pavlov. Cond. latency score0.10.10.3-0.4-0.4-0.00.0-0.10.6-0.1
Pavlov. Cond. lever contacts0.10.10.3-0.3-0.30.3-0.30.3-0.30.6
Pavlov. Cond. magazine entry number0.70.91.81.41.3-0.40.3-0.0-1.01.2
Pavlov. Cond. intertrial magazine entries0.40.61.51.21.1-0.70.6-0.5-0.10.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.7-0.70.1-0.1-0.00.6-0.3
Pavlov. Cond. response bias0.10.20.4-0.6-0.60.2-0.20.10.3-0.3
Time in closed arm before self-admin0.30.40.50.70.7-0.70.7-0.70.6-0.2
Time in closed arm after self-admin0.20.20.2-0.4-0.40.5-0.50.5-0.50.5
Time in open arm before self-admin0.40.40.6-0.7-0.80.7-0.70.7-0.50.2
Time in open arm after self-admin0.00.10.1-0.1-0.20.3-0.30.3-0.30.1
Bone: periosteal estimation0.10.30.40.60.7-0.60.6-0.60.40.3
Bone: periosteal perimeter0.40.70.90.80.8-0.90.9-0.90.9-0.3
Bone: post-yield work7.09.514.62.32.3-3.23.3-3.53.8-2.8
Progressive ratio test 1 active lever presses0.70.71.41.21.2-0.80.8-0.70.2-0.4
Progressive ratio test 1 breakpoint0.40.51.11.01.0-0.70.6-0.50.0-0.2
Progressive ratio test 1 inactive lever presses0.40.50.60.70.8-0.70.7-0.70.4-0.7
Progressive ratio test 2 active lever presses1.82.03.81.91.9-1.51.4-1.30.6-0.3
Progressive ratio test 2 breakpoint1.51.63.71.91.8-1.31.2-1.10.20.2
Progressive ratio test 2 inactive lever presses6.06.911.83.43.3-2.82.8-2.61.6-1.0
Incentive Sensitization - Responses0.30.30.50.70.6-0.50.5-0.50.3-0.3
Incentive Sensitization - Breakpoint0.40.40.80.90.8-0.70.6-0.60.3-0.3
Sum of active levers in priming session hrs 5-62.92.84.2-1.4-1.31.7-1.81.9-2.01.4
Progressive ratio1.31.54.5-0.4-0.2-0.70.8-1.01.9-2.1
Food seeking constrained by brief footshock0.10.10.4-0.6-0.40.3-0.30.20.1-0.5
Seeking ratio, punishment vs. effort0.70.92.40.20.20.5-0.60.8-1.51.5
Retroperitoneal fat weight2.89.318.04.24.2-3.23.1-2.81.20.1
Reaction time number correct1.01.51.7-1.2-1.21.3-1.31.3-1.21.0
Reaction time mean minus median0.60.81.7-1.2-1.20.6-0.50.40.4-1.3
Reaction time mean minus median AUC0.91.12.2-1.5-1.51.1-1.00.9-0.3-0.6
Reaction time num false alarms0.70.91.5-0.7-0.71.0-1.11.1-1.20.5
Reaction time num false alarms AUC1.11.51.9-1.3-1.31.4-1.41.4-1.20.1
Reaction time trials correct on left1.01.51.7-1.2-1.21.3-1.31.3-1.21.0
Reaction time trials on left1.31.82.1-1.3-1.41.5-1.51.4-1.31.0
Reaction time mean0.30.40.70.50.4-0.60.7-0.70.8-0.8
Reaction time mean AUC0.50.60.90.60.5-0.80.8-0.80.9-1.0
Median of all reaction times0.71.01.21.00.8-1.01.1-1.11.1-0.9
Reaction time omissions1.21.62.9-1.7-1.71.3-1.31.2-0.6-0.4
Reaction time false alarm rate0.20.30.5-0.5-0.50.6-0.70.7-0.7-0.0
Reaction time premature initiation rate1.62.24.2-2.0-2.01.5-1.51.4-0.6-0.4
Reaction time premature initiations3.65.18.3-2.9-2.82.5-2.42.3-1.50.2
Std. dev. reaction times0.20.21.0-0.5-0.50.1-0.10.00.4-1.0
Reaction time trials completed1.31.82.1-1.3-1.41.5-1.51.4-1.31.0
Reaction time trials AUC0.91.31.5-1.1-1.11.2-1.21.2-1.10.9
Run reversals in cocaine runway, females1.00.94.3-0.3-0.3-0.30.4-0.51.2-2.1
Run reversals in cocaine runway, males1.01.01.3-0.9-0.91.1-1.11.1-1.10.8
Latency to leave start box in cocaine runway1.11.21.80.90.8-1.11.2-1.21.3-1.0
Latency to leave start box in cocaine runway, F0.60.71.10.60.5-0.80.9-0.91.1-0.8
Latency to leave start box in cocaine runway, M0.10.10.10.20.2-0.20.2-0.30.2-0.2
Std. dev. time between licks in bursts1.72.12.7-1.4-1.41.6-1.61.6-1.60.5
Total sessions with >9 infusions0.80.91.21.01.1-1.01.0-1.00.8-0.5
Short access day 1 total inactive lever presses1.82.03.51.71.9-1.61.5-1.40.8-0.8
Short access day 10 total inactive lever presses1.01.11.81.31.3-1.11.1-1.00.6-0.6
Short access day 1 total infusions3.13.34.02.02.0-1.91.9-1.91.5-1.3
Short access day 10 total infusions4.24.75.91.91.8-2.22.3-2.32.4-2.2
Short access total infusions2.02.22.61.41.3-1.61.6-1.61.5-1.4
Short access day 1 locomotion2.42.63.21.71.7-1.81.8-1.81.5-0.8
Short access day 10 total locomotion1.31.51.81.21.2-1.31.3-1.31.2-0.9
Short access total locomotion1.21.21.50.91.1-1.21.2-1.21.1-0.8
One hour access (0.3 mA shock)4.85.610.43.23.1-2.52.4-2.21.1-0.7
Compulsive drug intake4.24.37.3-2.7-2.42.2-2.22.1-1.50.4
One hour access (shock baseline)5.66.512.83.63.4-2.72.6-2.41.2-0.3
Social response proportion0.30.31.0-0.7-0.60.1-0.1-0.00.5-1.0
Social responses0.60.81.2-1.1-1.00.9-0.90.9-0.60.3
Social time0.30.40.9-1.0-0.90.6-0.60.5-0.1-0.1
Soleus weight1.03.07.12.72.6-1.41.3-1.0-0.61.4
Bone: stiffness0.71.03.0-0.1-0.1-0.70.8-1.01.7-1.5
Tibialis anterior weight8.228.140.3-6.3-6.35.8-5.75.5-3.92.0
Time to tail flick, vehicle, before self-admin1.01.02.70.40.4-1.01.0-1.11.6-0.8
Time to tail flick, vehicle, after self-admin0.80.82.0-1.4-1.30.8-0.70.60.1-0.7
Time to tail flick, test, before self-admin1.61.52.60.90.9-1.31.3-1.41.6-1.1
Time to tail flick, test, after self-admin0.20.21.0-0.3-0.30.3-0.30.3-0.21.0
Delta time to tail flick, vehicle, before/after SA0.80.81.4-1.2-1.21.0-1.00.9-0.6-0.2
Delta time to tail flick, test, before/after SA4.23.84.4-1.7-1.62.0-2.02.1-2.12.1
Tibia length0.82.13.0-1.2-1.21.5-1.61.6-1.71.3
Ambulatory time before self-admin0.10.10.20.20.1-0.30.3-0.40.50.3
Ambulatory time after self-admin1.51.61.91.31.2-1.41.4-1.41.3-1.0
Bone: tissue strength0.30.30.40.50.6-0.60.6-0.60.5-0.2
Total heroin consumption2.22.65.3-2.3-2.21.7-1.71.5-0.60.1
Bone: trabecular number1.11.74.10.50.5-1.21.3-1.42.0-1.5
Bone: trabecular spacing0.40.51.5-0.2-0.20.5-0.60.7-1.01.2
Bone: trabecular thickness2.22.63.11.51.4-1.71.7-1.71.7-1.5
Bone: trabecular tissue density1.21.74.22.02.0-1.00.9-0.6-0.61.2
Water consumed over 24 hours0.10.10.3-0.5-0.50.2-0.10.00.4-0.2
Number of responses in last shaping day0.10.10.30.60.5-0.30.3-0.2-0.1-0.2