Hub : Genes

Hnrnpul2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Hnrnpul2 0.15 0.08 8.1e-09 0.07 0.06 0.06 0.07 1.9e-08 3.5e-07 1.2e-07 6.9e-08
2 OFC gene expression Hnrnpul2 0.4 0.16 4.1e-04 0.11 0.08 0.08 -0 1.3e-03 6.8e-03 5.1e-03 4.1e-01
3 LHb gene expression Hnrnpul2 0.32 0.15 5.2e-04 0.15 0.04 0.14 0.02 2.0e-04 4.4e-02 3.5e-04 9.5e-02
4 Brain gene expression Hnrnpul2 0.15 0.08 8.4e-09 0.1 0.06 0.1 0.02 2.9e-09 1.1e-06 1.5e-09 3.3e-03
5 Adipose gene expression Hnrnpul2 0.2 0.09 9.2e-11 0.09 0.08 0.07 0.07 9.7e-10 8.1e-09 4.8e-08 1.6e-08
6 NAcc gene expression Hnrnpul2 0.05 0.03 4.7e-06 0.04 0.04 0.03 0.03 1.9e-05 3.5e-05 7.2e-05 4.0e-04
7 IL gene expression Hnrnpul2 0.18 0.11 7.0e-04 0.1 0.09 0.09 0.07 2.2e-03 3.5e-03 3.2e-03 1.1e-02
8 pVTA gene expression Hnrnpul2 0.14 0.09 1.4e-03 0 0.02 0.01 0.01 2.9e-01 5.9e-02 1.4e-01 7.0e-02
9 LHb mRNA stability Hnrnpul2 0.29 0.14 1.7e-03 0 0.01 0.01 0.03 2.9e-01 1.6e-01 1.8e-01 7.2e-02
10 PL mRNA stability Hnrnpul2 0.1 0.06 1.6e-04 0.02 0.02 0.03 0.02 3.9e-03 1.0e-03 3.1e-04 1.9e-03
11 PL gene expression Hnrnpul2 0.18 0.09 2.6e-12 0.12 0.1 0.14 0.11 1.0e-12 1.9e-11 6.4e-15 2.8e-12
12 Adipose mRNA stability Hnrnpul2 0.05 0.03 6.9e-03 0.01 0.01 0.01 0.01 1.3e-02 4.4e-02 2.5e-02 4.2e-02
13 Brain mRNA stability Hnrnpul2 0.08 0.05 1.2e-03 0.02 0.03 0.02 0.03 3.8e-03 6.4e-04 3.7e-03 7.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.40.62.0-0.7-0.7-0.7-0.4-0.30.50.50.11.1-1.1-0.01.41.1
Area under the delay curve0.60.61.2-0.9-0.9-0.9-0.9-1.10.0-0.00.3-0.0-1.0-0.70.51.1
BMI with tail1.65.217.3-1.3-1.3-1.5-1.3-1.62.82.8-0.52.3-2.9-0.04.23.3
BMI without tail0.40.92.3-0.3-0.3-0.4-0.3-0.41.51.5-0.70.3-1.10.31.51.4
Body weight1.25.018.01.21.21.21.30.94.24.2-2.71.3-0.71.72.91.4
Weight adjusted by age0.80.92.30.50.50.60.70.61.51.5-0.81.3-0.01.11.20.2
Bone surface0.91.55.50.00.00.00.30.31.81.8-0.62.3-0.81.02.30.8
Bone volume0.61.15.0-0.4-0.4-0.3-0.1-0.01.11.10.02.2-1.00.72.00.8
Breakpoint value in progressive ratio session2.83.15.02.22.22.22.22.11.51.6-1.70.51.71.7-0.1-1.5
Number of licking bursts0.00.00.0-0.0-0.0-0.0-0.1-0.20.10.10.10.1-0.10.10.10.1
Context. condit. distance diff. score1.31.53.0-1.6-1.6-1.5-1.3-1.2-0.9-0.90.8-0.4-1.4-1.70.41.3
Locomotion velocity, session 10.50.51.8-0.8-0.8-0.7-0.6-0.6-0.2-0.2-0.1-1.0-0.7-1.30.00.8
Locomotion distance, session 10.40.61.6-0.7-0.7-0.7-0.6-0.70.50.5-0.4-0.2-1.1-0.80.81.3
Locomotion velocity, session 20.81.03.10.60.60.70.70.51.81.8-1.30.6-0.00.91.00.3
Locomotion distance, session 20.10.10.3-0.0-0.0-0.1-0.0-0.10.30.3-0.5-0.6-0.2-0.00.00.4
Locomotion velocity, session 31.51.74.2-1.5-1.5-1.3-1.3-1.50.50.50.40.6-1.8-0.91.72.0
Locomotion distance, session 30.10.10.3-0.2-0.2-0.0-0.1-0.20.30.3-0.2-0.4-0.2-0.6-0.00.4
Stereotopy head waving bouts, day 32.63.05.2-2.1-2.1-2.1-2.0-2.1-0.5-0.51.30.9-2.3-0.91.82.2
Stereotopy head waving duration, day 31.41.72.8-1.7-1.7-1.6-1.5-1.6-0.6-0.60.90.3-1.6-0.81.01.5
Locomotion velocity, session 70.50.61.0-1.0-1.0-0.9-0.8-0.8-0.3-0.30.70.6-0.9-0.40.80.9
Locomotion distance, session 70.91.12.2-1.3-1.3-1.3-1.2-1.2-0.5-0.50.6-0.4-1.3-1.50.51.3
Stereotopy head waving bouts, day 70.30.31.8-0.3-0.3-0.2-0.1-0.10.30.30.31.3-0.40.91.00.3
Stereotopy head waving duration, day 70.81.02.70.60.60.70.80.81.61.6-1.01.10.01.41.10.1
Locomotion velocity, session 80.20.31.9-0.3-0.3-0.2-0.2-0.1-0.4-0.4-0.3-1.40.0-0.6-0.80.1
Locomotion distance, session 81.31.93.2-1.8-1.8-1.7-1.5-1.5-0.8-0.81.10.2-1.7-1.30.91.6
Degree of sensitization distance2.12.13.7-1.7-1.7-1.8-1.7-1.7-0.4-0.41.10.7-1.9-1.11.51.8
Degree of sensitization stereotypy0.70.82.10.60.60.70.80.81.11.1-0.51.40.31.50.8-0.3
Conditioned locomotion0.20.20.60.20.20.40.50.50.80.8-0.70.10.00.70.20.0
Cocaine response after cond. corrected1.31.53.2-1.4-1.4-1.4-1.3-1.2-1.2-1.20.6-1.3-1.0-1.8-0.31.0
Cocaine response after cond. not corrected1.11.23.1-1.2-1.2-1.3-1.1-1.0-1.0-1.00.6-1.0-0.9-1.8-0.20.9
Cocaine response before conditioning0.60.71.11.11.11.00.90.90.80.8-0.40.90.80.60.2-0.8
Saline control response1.21.53.91.21.21.31.31.22.02.0-1.9-0.30.50.40.2-0.2
Bone: connectivity density0.61.03.3-0.3-0.3-0.20.10.01.61.6-0.71.3-1.00.41.81.1
Bone: cortical apparent density0.81.11.81.31.31.11.31.40.70.7-1.2-0.51.10.9-0.7-1.1
Bone: cortical area0.40.61.90.40.40.40.40.31.31.3-0.51.4-0.10.71.20.2
Bone: cortical porosity0.30.30.80.50.50.60.60.6-0.3-0.3-0.2-0.20.80.6-0.8-0.9
Bone: cortical porosity0.50.61.00.80.80.90.90.90.00.0-0.6-0.51.00.7-0.9-1.0
Bone: cortical thickness2.74.47.72.52.52.42.42.32.42.4-2.8-0.71.81.5-0.6-1.3
Bone: cortical thickness0.70.81.81.01.01.01.01.00.70.7-1.3-1.10.90.2-0.8-0.6
Bone: cortical tissue density1.01.42.21.41.41.31.41.50.80.8-1.4-0.51.21.0-0.7-1.2
Condit. Reinf. active minus inactive responses0.40.51.20.60.60.60.70.61.11.1-0.90.40.20.50.6-0.0
Condit. Reinf. active-inactive response ratio0.40.50.90.70.70.80.90.90.60.6-0.9-0.40.60.2-0.3-0.5
Condit. Reinf. active responses0.40.51.90.20.20.20.30.21.11.1-0.41.4-0.30.61.30.3
Condit. Reinf. inactive responses0.60.82.9-0.6-0.6-0.7-0.7-0.80.10.10.91.7-0.90.11.40.8
Incentive salience index mean0.40.51.70.20.20.20.20.11.31.3-0.70.8-0.50.21.30.7
Condit. Reinf. lever presses0.40.62.3-0.2-0.2-0.3-0.3-0.41.11.1-0.30.9-0.9-0.21.51.1
Condit. Reinf. active minus inactive responses0.20.20.8-0.0-0.00.20.10.2-0.5-0.50.70.90.30.5-0.0-0.6
Condit. Reinf. active-inactive response ratio0.91.03.9-0.9-0.9-0.7-0.7-0.7-0.8-0.81.62.0-0.60.61.00.2
Condit. Reinf. active responses0.10.10.20.40.40.40.30.40.20.2-0.00.30.40.2-0.1-0.4
Condit. Reinf. inactive responses0.40.62.20.70.70.50.50.50.40.4-1.0-1.50.6-0.7-0.8-0.2
Condit. Reinf. lever presses0.50.71.60.80.80.70.70.71.31.3-0.61.20.20.90.9-0.1
Condit. Reinf. lever reinforcers received0.20.30.60.70.70.70.70.70.50.5-0.40.50.70.6-0.1-0.6
Conditioned reinforcement - actives0.80.82.3-0.7-0.7-0.7-0.8-0.8-1.5-1.51.50.8-0.00.1-0.5-0.5
Conditioned reinforcement - inactives1.31.42.7-1.5-1.5-1.4-1.4-1.4-0.9-0.91.61.4-1.1-0.10.60.6
Conditioned locomotion2.93.56.0-2.4-2.4-2.3-2.4-2.4-1.5-1.52.20.7-1.8-1.30.61.3
Patch foraging indifference point 0 sec0.20.30.80.30.30.40.50.50.90.9-0.70.30.00.20.50.2
Patch foraging indifference point AUC2.32.65.01.81.81.81.71.61.81.8-1.31.71.12.20.8-1.1
Delay disc. indifference point, 0s delay2.12.33.8-1.9-1.9-2.0-1.9-1.9-0.6-0.70.9-0.3-1.8-1.70.71.9
Delay disc. indifference point, 16s delay0.40.41.0-0.6-0.6-0.6-0.6-0.80.30.30.30.9-0.80.11.00.8
Delay disc. indifference point, 2s delay1.11.22.3-1.4-1.4-1.4-1.4-1.5-0.5-0.51.00.5-1.2-0.80.81.2
Delay disc. indifference point, 24s delay0.20.20.7-0.2-0.2-0.2-0.2-0.20.30.3-0.4-0.7-0.4-0.80.00.5
Delay disc. indifference point, 4s delay0.60.61.6-0.9-0.9-0.9-0.8-0.90.40.3-0.3-0.6-1.0-1.00.51.3
Delay disc. indifference point, 8s delay0.60.61.5-0.8-0.8-0.8-0.8-0.9-0.6-0.70.3-1.0-0.6-1.2-0.40.6
Indifference point function ln k5.06.916.2-2.9-2.9-2.9-2.9-2.8-2.5-2.51.8-2.5-2.1-4.0-0.72.2
Indifference point function log k5.06.916.2-2.9-2.9-2.9-2.9-2.8-2.5-2.51.8-2.5-2.1-4.0-0.72.2
Patch foraging total patch changes 0 sec0.20.41.10.50.50.60.70.70.90.9-1.0-0.30.30.00.0-0.0
Patch foraging total patch changes 12 sec4.25.59.02.52.52.62.72.63.03.0-2.71.21.52.60.8-1.2
Patch foraging total patch changes 18 sec0.81.01.61.31.31.11.21.20.70.7-0.90.61.01.1-0.1-1.0
Patch foraging total patch changes 24 sec2.93.59.61.61.61.71.81.63.13.1-2.51.20.41.71.60.1
Patch foraging total patch changes 6 sec0.30.51.70.30.30.60.70.61.31.3-1.10.4-0.10.20.70.2
Patch foraging time to switch 0 sec0.50.83.1-0.6-0.6-0.6-0.4-0.40.60.60.21.7-0.90.61.60.8
Patch foraging water rate 0 sec0.20.41.5-0.1-0.10.0-0.00.0-0.8-0.80.1-1.20.4-0.8-1.2-0.3
Patch foraging water rate 12 sec1.32.06.7-1.0-1.0-1.0-1.1-1.1-1.5-1.60.7-2.6-0.3-2.6-1.50.5
Patch foraging water rate 18 sec1.62.17.1-1.5-1.5-1.4-1.4-1.4-1.0-1.00.5-2.1-1.1-2.7-0.51.4
Patch foraging water rate 24 sec0.91.33.1-1.0-1.0-0.8-0.9-0.9-1.5-1.50.7-1.6-0.3-1.8-1.20.3
Patch foraging water rate 6 sec1.01.44.7-0.8-0.8-0.8-1.0-1.0-1.3-1.30.5-2.2-0.3-2.0-1.30.5
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.2-0.2-0.2-0.2-0.20.0-0.0-0.0-0.0-0.3-0.30.10.4
Distance traveled before self-admin1.51.63.11.31.31.31.31.31.71.7-1.21.30.61.60.8-0.5
Distance traveled after self-admin0.70.71.41.01.01.11.01.10.70.7-0.60.50.81.2-0.0-0.8
Extensor digitorum longus weight2.49.629.82.52.52.52.62.25.55.5-4.01.60.12.82.90.7
Bone: elastic displacement0.50.62.30.20.20.30.30.4-0.8-0.8-0.1-1.50.7-0.2-1.5-0.7
Bone: elastic work0.50.72.00.70.70.80.90.90.90.9-1.4-1.10.50.2-0.5-0.2
Bone: endosteal estimation3.47.510.8-3.3-3.3-3.2-3.2-3.1-1.6-1.63.02.2-3.1-1.72.52.7
Bone: endosteal perimeter3.87.812.7-3.2-3.2-3.2-3.2-3.2-1.8-1.83.62.9-3.0-1.32.52.4
Epididymis fat weight1.12.64.9-1.8-1.8-2.0-2.1-2.2-0.6-0.61.70.7-1.9-0.91.41.9
Delta time in closed arm before/after self-admin0.70.71.8-0.2-0.2-0.2-0.1-0.31.01.0-1.2-1.3-0.6-1.10.41.2
Delta time in open arm before/after self-admin1.61.54.01.21.21.21.31.31.31.3-0.81.60.72.00.7-0.8
Diff in mean of infusions in LGA sessions2.83.04.92.22.22.22.22.21.41.4-1.9-0.21.81.5-0.6-1.5
Delay discount exponential model param0.50.51.10.90.90.90.91.1-0.00.0-0.20.10.90.8-0.5-1.0
Extinction: sum of active levers before priming2.32.34.51.61.61.61.61.52.12.1-1.70.90.81.60.8-0.5
Active lever presses in extinction session 63.23.14.52.12.12.12.12.01.81.8-1.61.11.42.10.3-1.4
Bone: final force0.71.23.60.30.30.20.40.31.91.9-0.91.5-0.60.71.80.8
Bone: final moment0.71.23.50.30.30.30.40.41.91.9-0.91.5-0.50.71.70.7
Food consumed during 24 hour testing period0.10.10.20.30.30.30.30.4-0.1-0.10.20.40.30.1-0.2-0.5
Glucose2.53.86.7-2.3-2.3-2.3-2.4-2.4-2.0-2.02.60.5-1.7-1.60.51.4
Heart weight1.72.34.0-1.8-1.8-2.0-1.9-1.9-1.2-1.21.3-0.8-1.5-1.60.41.6
Delay discount hyperbolic model param0.60.61.31.01.01.00.91.1-0.00.0-0.30.01.00.8-0.6-1.1
Intermittent access intake day 1-15 change0.80.82.30.70.70.50.40.5-1.2-1.20.70.51.10.7-1.2-1.5
Intermittent access intake escalation0.60.61.90.70.70.50.40.6-0.9-0.90.50.41.00.6-1.0-1.4
Intermittent access intake escalation 20.80.81.81.21.21.00.91.0-0.1-0.1-0.10.81.10.9-0.5-1.4
Intermitt. access day 1 inactive lever presses1.61.72.9-1.6-1.6-1.5-1.6-1.5-1.5-1.51.70.4-0.9-0.9-0.10.6
Intermitt. access day 15 inactive lever presses1.11.23.4-1.1-1.1-1.1-1.0-1.10.30.30.91.8-1.30.41.51.1
Intermitt. access escalation Index0.90.81.5-1.1-1.1-1.1-1.1-1.1-0.5-0.50.4-0.8-0.9-1.20.11.1
Intermittent access day 1 total infusions7.08.114.2-3.8-3.8-3.6-3.6-3.7-0.9-0.92.41.5-3.4-1.72.23.1
Intermittent access day 15 total infusions3.94.37.3-2.6-2.6-2.6-2.6-2.6-1.9-1.92.71.4-1.8-1.00.61.2
Intermittent access terminal intake (last 3 days)3.13.45.2-2.3-2.3-2.3-2.3-2.3-0.7-0.72.02.2-2.1-0.41.61.5
Intermittent access total infusions3.74.16.7-2.6-2.6-2.6-2.6-2.6-1.0-1.02.11.7-2.3-0.71.51.8
Intermittent access day 1 locomotion6.87.112.2-3.5-3.5-3.4-3.3-3.4-0.4-0.41.71.0-3.4-1.82.33.2
Intermittent access day 15 total locomotion2.22.43.9-2.0-2.0-1.9-1.8-1.9-0.3-0.31.41.5-1.8-0.61.51.5
Intermittent access total locomotion6.47.311.4-3.4-3.4-3.3-3.2-3.3-0.2-0.22.12.6-3.4-1.02.82.9
Intermittent access standard deviation0.40.51.40.10.10.0-0.10.0-1.2-1.20.80.20.60.1-1.0-1.0
Left kidney weight0.20.51.7-0.4-0.4-0.6-0.6-0.60.30.30.51.1-0.90.51.30.8
Right kidney weight0.30.83.3-0.2-0.2-0.5-0.4-0.40.50.50.51.8-0.81.21.60.6
Cocaine induced anxiety0.20.20.80.40.40.40.40.40.50.5-0.30.90.10.50.4-0.2
Post-drug Anxiety0.70.71.20.90.90.90.90.90.90.9-0.61.10.61.10.3-0.7
Baseline Anxiety0.90.91.61.21.21.21.21.21.11.1-1.3-0.30.70.70.0-0.4
Tail length1.23.75.72.22.22.32.32.21.81.7-2.4-1.21.81.8-0.9-1.3
Length with tail1.34.810.52.32.32.42.42.23.23.2-2.90.21.22.10.8-0.6
Length without tail0.81.85.51.31.31.21.10.92.32.3-1.60.90.21.21.30.1
Times rat made contact with spout0.40.51.20.60.60.80.70.70.30.3-0.9-1.10.7-0.1-1.0-0.5
Lifetime Intake3.64.17.1-2.6-2.6-2.7-2.6-2.7-1.0-1.02.01.1-2.3-1.11.32.0
Liver weight, left0.20.20.6-0.3-0.3-0.3-0.3-0.3-0.7-0.70.4-0.60.0-0.8-0.7-0.0
Liver weight, right0.40.61.4-0.8-0.8-0.9-0.9-1.00.00.00.3-0.0-1.0-1.10.71.2
Locomotor activity0.71.15.1-0.5-0.5-0.2-0.4-0.4-1.1-1.10.1-2.30.2-1.7-1.60.0
Locomotor testing distance1.11.86.7-1.1-1.1-0.8-0.9-0.9-1.3-1.30.2-2.6-0.3-2.4-1.50.6
Locomotor testing rearing0.81.24.0-0.8-0.8-0.8-0.9-0.9-1.3-1.30.6-1.7-0.3-2.0-1.20.5
Locomotion in novel chamber1.82.25.0-1.9-1.9-1.6-1.7-1.7-1.5-1.52.21.4-1.2-0.20.50.7
Locomotion in novel chamber post-restriction1.11.33.8-1.1-1.1-1.1-1.1-1.1-1.9-1.91.6-0.1-0.4-0.6-0.7-0.1
Fecal boli incidents, locomotor time 10.30.32.20.00.0-0.0-0.10.0-0.3-0.40.81.50.20.80.3-0.4
Change in fecal boli incidents, locomotor task1.71.63.9-1.4-1.4-1.3-1.4-1.5-0.9-1.00.6-1.5-1.0-2.0-0.41.2
Time >=10cm from walls, locomotor time 12.32.35.3-1.8-1.8-1.7-1.7-1.7-1.3-1.42.31.6-1.3-0.40.80.8
Bouts of movement, locomotor time 13.74.07.22.42.42.52.52.70.50.5-1.3-0.52.61.6-1.8-2.6
Total resting periods, locomotor time 12.73.05.32.12.12.22.12.30.50.5-1.1-0.12.11.6-1.3-2.2
Rest time, locomotor task time 10.50.51.80.10.1-0.1-0.2-0.0-1.3-1.40.7-0.50.50.1-1.1-0.7
Distance moved, locomotor task time 10.20.20.6-0.4-0.4-0.2-0.3-0.50.60.6-0.10.3-0.6-0.40.80.7
Vertical activity count, locomotor time 10.50.61.2-0.9-0.9-0.8-0.8-0.9-0.8-0.80.8-0.2-0.5-1.1-0.10.4
Time >=10cm from walls, locomotor time 20.30.30.80.50.50.60.60.6-0.1-0.20.30.80.70.8-0.3-0.9
Bouts of movement, locomotor time 21.21.22.01.41.41.21.31.21.31.2-1.40.00.91.1-0.1-0.7
Total resting periods, locomotor time 20.60.61.01.01.00.90.90.90.90.8-0.90.10.70.8-0.1-0.5
Rest time, locomotor task time 21.61.94.5-1.4-1.4-1.4-1.5-1.4-2.1-2.11.8-0.5-0.6-1.2-0.80.3
Distance moved, locomotor task time 21.11.32.21.41.41.51.51.40.90.8-1.1-0.21.20.8-0.5-1.1
Vertical activity count, locomotor time 20.91.02.31.01.01.11.01.1-0.1-0.1-0.9-1.51.2-0.2-1.5-1.1
Light reinforcement 10.20.30.60.80.80.40.30.4-0.3-0.3-0.1-0.60.8-0.2-0.8-0.7
Light reinforcement 20.50.74.7-0.3-0.3-0.5-0.5-0.5-0.3-0.31.22.2-0.40.81.10.0
Bone: marrow area3.57.711.1-3.3-3.3-3.3-3.2-3.2-1.7-1.73.12.1-3.1-1.82.42.7
Bone: maximum diameter0.40.84.2-0.5-0.5-0.6-0.6-0.60.50.50.62.0-0.90.31.70.7
Bone: maximum force1.42.59.4-0.4-0.4-0.4-0.3-0.42.22.2-0.52.6-1.50.63.11.7
Bone: maximum moment1.32.38.3-0.3-0.3-0.3-0.2-0.32.22.2-0.52.5-1.40.62.91.6
Mean time between licks in bursts0.40.63.10.20.20.30.30.20.90.9-1.3-1.8-0.2-0.8-0.30.6
Mean num. licks in bursts0.20.30.90.30.30.40.40.5-0.2-0.2-0.4-0.90.6-0.2-0.9-0.5
Cd content in liver0.70.81.9-0.9-0.9-0.9-0.8-0.6-1.4-1.41.20.2-0.4-1.0-0.20.0
Co content in liver1.72.08.00.30.30.20.20.4-1.6-1.6-0.1-2.81.3-1.5-2.7-1.2
Cu content in liver0.20.31.00.40.40.40.50.50.40.4-0.8-1.00.3-0.1-0.4-0.1
Fe content in liver0.00.00.2-0.2-0.2-0.2-0.1-0.1-0.1-0.10.20.4-0.20.00.40.0
K content in liver0.80.83.2-0.3-0.3-0.2-0.1-0.21.21.2-0.11.4-0.90.41.81.0
Mg content in liver1.11.13.1-1.0-1.0-0.9-0.8-0.80.70.70.41.2-1.4-0.41.81.5
Mn content in liver1.21.43.31.01.01.21.21.11.81.8-1.11.10.31.31.0-0.2
Na content in liver0.40.41.40.40.40.40.40.30.90.9-0.31.2-0.10.71.10.1
Rb content in liver1.41.82.6-1.6-1.6-1.5-1.6-1.5-1.4-1.41.4-0.7-1.2-1.6-0.11.1
Se content in liver0.50.73.90.10.10.20.20.20.60.60.32.0-0.31.31.40.0
Sr content in liver3.43.15.91.91.91.81.81.62.42.4-2.20.81.12.30.4-0.9
Zn content in liver1.81.94.91.11.11.21.21.12.22.2-1.61.40.31.71.3-0.1
Bone: minimum diameter2.75.07.1-2.6-2.6-2.6-2.5-2.5-0.9-0.92.42.3-2.7-1.12.52.3
Time in familiar zone, hab. session 10.20.20.4-0.4-0.4-0.3-0.2-0.20.30.3-0.00.2-0.5-0.60.50.6
Time in novel zone, hab. session 10.60.61.5-0.4-0.4-0.4-0.6-0.5-1.2-1.20.6-1.10.1-0.9-1.1-0.2
Total zone transitions, hab. session 10.10.20.40.50.50.40.40.30.50.5-0.6-0.10.20.40.1-0.2
Total locomotion distance, hab. session 10.60.81.2-1.0-1.0-1.1-1.0-1.1-0.4-0.40.90.9-1.1-0.51.00.9
Locomotion velocity, hab. session 10.20.20.8-0.3-0.3-0.4-0.4-0.50.20.20.20.9-0.60.10.90.5
Time in familiar zone, hab. session 20.60.62.30.40.40.60.50.6-0.3-0.3-0.3-1.50.9-0.6-1.5-0.7
Time in novel zone, hab. session 20.50.51.7-0.5-0.5-0.6-0.4-0.60.60.6-0.01.0-0.90.11.30.9
Total zone transitions, hab. session 20.40.51.7-0.0-0.00.00.10.01.31.3-1.00.0-0.6-0.30.90.9
Total locomotion distance, hab. session 20.40.51.3-0.8-0.8-0.7-0.7-0.80.20.20.10.3-1.0-0.90.91.1
Locomotion velocity, hab. session 20.60.81.5-0.9-0.9-1.0-1.0-1.10.10.10.50.6-1.2-0.81.11.2
Novel to familiar place preference ratio1.11.12.60.90.90.70.80.51.61.6-0.91.40.11.61.2-0.0
Novelty place preference0.80.82.10.70.70.60.60.41.31.3-0.61.30.01.51.1-0.0
Time in novel zone, NPP test0.70.71.70.60.60.50.50.41.31.3-0.61.2-0.01.31.10.1
Total zone transitions, NPP test0.30.41.40.30.30.40.60.51.11.1-1.2-0.2-0.00.20.40.3
Total locomotion distance, NPP test0.20.30.5-0.6-0.6-0.6-0.5-0.6-0.0-0.0-0.1-0.2-0.7-0.70.30.7
Locomotion velocity, NPP test0.10.10.2-0.4-0.4-0.4-0.3-0.4-0.1-0.1-0.1-0.2-0.4-0.50.10.4
Intraocular pressure0.40.51.10.80.80.90.70.7-0.2-0.2-0.1-0.11.00.8-0.9-1.1
Delta distance traveled before/after self-admin0.30.31.1-0.4-0.4-0.2-0.3-0.2-0.8-0.80.3-1.00.1-0.6-0.8-0.1
Delta ambulatory time before/after self-admin0.50.52.0-0.3-0.3-0.3-0.3-0.3-1.1-1.00.4-1.40.2-0.9-1.1-0.1
Parametrial fat weight2.14.26.7-2.5-2.5-2.4-2.5-2.6-1.6-1.62.51.1-2.0-1.51.11.6
Pavlov. Cond. lever latency0.60.72.90.10.10.10.10.1-1.3-1.30.4-1.20.8-0.1-1.7-0.9
Pavlov. Cond. magazine entry latency0.60.83.30.10.10.20.30.21.31.3-0.21.8-0.40.51.60.5
Pavlov. Cond. change in total contacts0.40.53.5-0.1-0.10.00.10.10.60.60.31.9-0.30.51.20.1
Pavlov. Cond. index score0.30.41.50.40.40.50.50.51.01.0-0.41.20.00.50.9-0.0
Pavlov. Cond. latency score0.20.31.00.10.10.20.20.20.90.9-0.31.0-0.30.11.00.3
Pavlov. Cond. lever contacts0.20.20.9-0.2-0.2-0.2-0.1-0.20.60.6-0.00.8-0.5-0.20.90.6
Pavlov. Cond. magazine entry number0.70.81.5-0.9-0.9-1.0-1.0-1.1-1.0-1.00.6-1.2-0.7-1.0-0.50.7
Pavlov. Cond. intertrial magazine entries0.60.71.91.01.00.90.90.90.10.1-0.30.41.01.4-0.4-1.2
Pavlov. Cond. lever-magazine prob. diff.0.50.62.00.40.40.60.60.61.11.1-0.41.40.10.71.0-0.1
Pavlov. Cond. response bias0.40.51.90.50.50.60.60.61.01.0-0.41.40.10.71.0-0.1
Pavlov. Cond. lever latency0.20.31.1-0.0-0.00.0-0.0-0.0-0.8-0.80.2-0.90.4-0.1-1.0-0.5
Pavlov. Cond. magazine entry latency2.63.05.61.91.91.91.91.92.42.4-2.10.71.11.40.6-0.8
Pavlov. Cond. change in total contacts1.01.43.11.11.11.11.21.21.61.6-0.81.80.51.11.1-0.5
Pavlov. Cond. index score1.41.84.01.31.31.21.31.32.02.0-1.21.60.41.21.3-0.3
Pavlov. Cond. latency score1.21.43.41.01.01.01.01.01.91.9-1.11.60.21.11.4-0.1
Pavlov. Cond. lever contacts0.30.40.60.70.70.70.70.80.80.8-0.60.60.40.50.3-0.4
Pavlov. Cond. magazine entry number3.94.810.0-2.3-2.3-2.3-2.3-2.3-3.2-3.22.5-1.5-1.1-2.1-1.20.8
Pavlov. Cond. intertrial magazine entries0.50.72.4-0.5-0.5-0.7-0.8-0.7-1.6-1.61.3-0.20.1-0.2-0.8-0.3
Pavlov. Cond. lever-magazine prob. diff.1.62.04.51.41.41.31.41.42.12.1-1.41.40.51.21.2-0.4
Pavlov. Cond. response bias1.01.32.71.31.31.21.21.21.61.6-1.20.90.61.00.6-0.5
Time in closed arm before self-admin0.20.21.40.00.0-0.0-0.00.0-0.10.00.51.2-0.00.90.5-0.1
Time in closed arm after self-admin0.60.61.0-0.9-0.9-0.9-1.0-1.0-0.8-0.80.7-0.7-0.6-1.0-0.20.7
Time in open arm before self-admin1.21.36.5-0.7-0.7-0.7-0.8-0.8-1.0-1.10.1-2.6-0.1-1.9-1.40.4
Time in open arm after self-admin0.70.71.11.01.01.01.01.00.10.1-0.8-0.81.10.4-0.9-1.0
Bone: periosteal estimation1.42.86.2-1.7-1.7-1.7-1.7-1.7-0.1-0.11.62.5-2.1-0.42.41.8
Bone: periosteal perimeter0.71.14.1-0.8-0.8-1.0-1.0-1.00.00.01.12.0-1.10.01.60.9
Bone: post-yield work3.85.210.2-2.4-2.4-2.5-2.3-2.3-0.5-0.52.33.2-2.8-0.83.12.3
Progressive ratio test 1 active lever presses1.41.52.5-1.5-1.5-1.4-1.5-1.5-1.5-1.51.60.2-0.8-0.6-0.20.4
Progressive ratio test 1 breakpoint1.41.52.7-1.4-1.4-1.4-1.5-1.5-1.6-1.61.60.1-0.7-0.6-0.30.3
Progressive ratio test 1 inactive lever presses0.40.41.0-0.8-0.8-0.8-0.8-0.80.10.10.1-0.0-0.9-0.50.61.0
Progressive ratio test 2 active lever presses2.22.43.9-1.9-1.9-1.9-2.0-2.0-1.3-1.32.01.2-1.4-0.40.60.9
Progressive ratio test 2 breakpoint2.02.34.6-1.8-1.8-1.8-1.9-1.8-1.8-1.82.10.9-1.1-0.50.00.5
Progressive ratio test 2 inactive lever presses2.32.74.4-2.1-2.1-2.0-2.0-2.1-0.8-0.81.81.6-1.8-0.41.21.3
Incentive Sensitization - Responses0.60.62.0-0.7-0.7-0.7-0.7-0.70.30.30.51.4-0.90.41.10.7
Incentive Sensitization - Breakpoint0.70.72.1-0.8-0.8-0.9-0.8-0.80.20.20.71.5-1.00.31.20.8
Sum of active levers in priming session hrs 5-63.83.76.32.42.42.32.32.31.11.2-1.11.52.02.5-0.2-2.1
Progressive ratio0.30.31.0-0.4-0.4-0.4-0.4-0.40.30.30.51.0-0.60.30.90.6
Food seeking constrained by brief footshock0.10.20.7-0.3-0.3-0.2-0.2-0.2-0.3-0.40.0-0.9-0.1-0.6-0.50.2
Seeking ratio, punishment vs. effort0.30.42.6-0.1-0.1-0.0-0.0-0.1-0.5-0.5-0.4-1.60.2-1.0-1.0-0.1
Retroperitoneal fat weight2.78.813.9-3.6-3.6-3.6-3.7-3.7-2.8-2.83.50.0-2.7-2.60.72.4
Reaction time number correct0.50.71.30.80.81.10.90.81.11.1-1.2-0.70.60.1-0.3-0.2
Reaction time mean minus median1.41.95.41.51.51.51.51.50.60.7-0.51.51.42.3-0.1-1.6
Reaction time mean minus median AUC1.62.03.81.71.71.71.61.70.30.4-0.70.31.81.9-0.9-1.9
Reaction time num false alarms0.60.85.00.20.2-0.00.00.1-0.7-0.7-0.5-2.20.4-1.3-1.5-0.2
Reaction time num false alarms AUC0.71.05.50.70.70.50.60.6-0.2-0.2-1.1-2.30.8-0.9-1.5-0.5
Reaction time trials correct on left0.50.71.30.80.81.10.90.81.11.1-1.2-0.70.60.1-0.3-0.2
Reaction time trials on left0.50.81.50.90.91.21.00.91.11.1-1.2-0.70.70.2-0.4-0.3
Reaction time mean0.40.51.40.70.70.60.70.8-0.3-0.30.10.80.91.1-0.4-1.2
Reaction time mean AUC0.30.51.30.60.60.50.60.7-0.4-0.30.20.80.81.0-0.4-1.1
Median of all reaction times0.10.20.50.30.30.20.30.5-0.1-0.10.00.70.40.70.1-0.6
Reaction time omissions1.01.42.51.41.41.31.41.40.00.1-1.0-0.61.50.9-1.3-1.6
Reaction time false alarm rate0.30.52.6-0.1-0.1-0.4-0.3-0.2-0.8-0.8-0.1-1.60.0-1.0-1.0-0.0
Reaction time premature initiation rate1.21.75.90.90.90.70.70.62.42.4-2.1-0.5-0.3-0.01.10.9
Reaction time premature initiations2.23.18.51.81.81.71.61.42.92.9-2.9-1.00.60.30.50.2
Std. dev. reaction times1.11.53.91.31.31.31.31.4-0.3-0.3-0.20.51.61.7-1.0-2.0
Reaction time trials completed0.50.81.50.90.91.21.00.91.11.1-1.2-0.70.70.2-0.4-0.3
Reaction time trials AUC0.40.51.10.70.70.90.80.71.01.0-1.1-0.70.5-0.1-0.3-0.1
Run reversals in cocaine runway, females1.41.43.9-1.2-1.2-1.1-1.0-1.10.80.8-0.4-0.6-1.6-1.31.22.0
Run reversals in cocaine runway, males0.20.20.7-0.2-0.20.0-0.00.0-0.8-0.80.4-0.60.4-0.2-0.8-0.4
Latency to leave start box in cocaine runway1.41.62.7-1.4-1.4-1.6-1.6-1.6-0.6-0.61.20.7-1.5-1.01.01.3
Latency to leave start box in cocaine runway, F0.10.10.3-0.4-0.4-0.3-0.4-0.40.10.10.20.5-0.5-0.20.50.4
Latency to leave start box in cocaine runway, M2.42.33.6-1.6-1.6-1.8-1.9-1.8-1.9-1.91.9-0.1-1.2-1.5-0.10.8
Std. dev. time between licks in bursts0.40.52.8-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.2-1.7-0.3-1.4-0.80.5
Total sessions with >9 infusions4.04.47.6-2.6-2.6-2.8-2.7-2.8-1.5-1.52.00.0-2.2-1.70.72.0
Short access day 1 total inactive lever presses2.93.26.0-2.5-2.5-2.3-2.2-2.3-1.0-1.01.60.1-1.9-1.40.81.8
Short access day 10 total inactive lever presses1.92.13.5-1.7-1.7-1.6-1.6-1.5-1.7-1.71.3-1.3-0.8-1.9-0.70.8
Short access day 1 total infusions2.62.85.1-2.1-2.1-2.2-2.2-2.3-1.1-1.11.50.1-1.8-1.20.61.6
Short access day 10 total infusions4.85.49.1-2.9-2.9-3.0-2.9-3.0-0.5-0.51.71.1-2.9-1.32.02.7
Short access total infusions3.53.96.8-2.5-2.5-2.6-2.6-2.6-0.8-0.81.50.3-2.3-1.41.32.2
Short access day 1 locomotion2.83.05.4-2.2-2.2-2.2-2.1-2.20.10.10.90.7-2.3-1.01.72.3
Short access day 10 total locomotion2.02.33.9-1.8-1.8-1.9-1.8-1.90.00.00.90.9-2.0-0.91.61.9
Short access total locomotion3.13.25.9-2.1-2.1-2.2-2.1-2.20.30.30.80.9-2.4-1.12.02.4
One hour access (0.3 mA shock)4.04.67.5-2.7-2.7-2.7-2.7-2.7-2.2-2.22.70.8-1.8-1.10.21.2
Compulsive drug intake2.52.54.31.81.81.91.91.91.01.0-2.1-2.01.50.4-1.0-0.8
One hour access (shock baseline)3.84.59.7-2.4-2.4-2.5-2.6-2.5-2.5-2.53.11.7-1.5-0.70.20.5
Social response proportion0.10.10.20.30.30.20.0-0.00.50.5-0.4-0.20.0-0.20.10.2
Social responses0.70.91.51.21.21.11.01.00.30.3-0.9-0.91.20.3-1.2-1.0
Social time0.50.61.31.01.00.80.70.6-0.1-0.1-0.6-1.11.00.3-1.1-0.8
Soleus weight1.44.29.2-2.1-2.1-2.1-2.1-2.0-3.0-3.02.5-0.9-1.1-2.3-0.80.7
Bone: stiffness0.50.93.90.10.10.10.1-0.01.31.3-0.12.0-0.50.81.70.5
Tibialis anterior weight4.716.037.73.93.93.94.13.76.16.1-5.11.91.54.52.3-0.8
Time to tail flick, vehicle, before self-admin1.11.13.0-1.0-1.0-1.0-0.9-1.00.60.70.31.4-1.40.11.71.4
Time to tail flick, vehicle, after self-admin0.30.41.1-0.5-0.5-0.6-0.5-0.50.60.6-0.3-0.2-0.8-0.50.71.1
Time to tail flick, test, before self-admin2.01.94.5-1.7-1.7-1.6-1.5-1.60.40.40.30.2-1.9-0.91.52.1
Time to tail flick, test, after self-admin0.00.00.10.10.10.0-0.0-0.0-0.4-0.30.2-0.10.20.2-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.70.10.10.10.10.10.0-0.0-0.3-0.80.1-0.5-0.40.0
Delta time to tail flick, test, before/after SA2.52.34.61.91.91.81.71.8-0.1-0.1-0.6-0.22.01.2-1.4-2.1
Tibia length1.02.89.01.11.11.31.21.12.32.3-0.93.00.32.31.9-0.4
Ambulatory time before self-admin2.02.15.41.51.51.51.51.51.61.6-1.11.60.82.30.8-0.8
Ambulatory time after self-admin0.30.31.40.30.30.40.40.40.60.6-0.01.20.10.80.6-0.2
Bone: tissue strength0.10.10.20.10.1-0.0-0.2-0.2-0.2-0.20.3-0.30.1-0.4-0.30.0
Total heroin consumption4.65.48.82.92.93.02.92.82.22.2-2.6-0.02.21.9-0.5-1.9
Bone: trabecular number0.50.93.1-0.6-0.6-0.4-0.2-0.21.01.0-0.11.5-1.10.31.71.1
Bone: trabecular spacing0.60.83.20.80.80.60.40.4-0.5-0.5-0.3-1.81.0-0.7-1.6-0.8
Bone: trabecular thickness0.30.31.2-0.7-0.7-0.6-0.4-0.3-0.6-0.60.91.1-0.40.40.40.1
Bone: trabecular tissue density1.62.37.4-0.7-0.7-1.0-1.2-1.1-2.7-2.71.7-1.40.3-1.4-1.8-0.7
Water consumed over 24 hours0.60.81.21.11.11.11.01.00.80.8-1.1-0.60.80.5-0.5-0.6
Number of responses in last shaping day0.10.20.8-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.8-0.1-0.9-0.20.3