Hub : Genes

Hnrnpul2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Hnrnpul2 0.35 0.18 7.2e-04 0.16 0.05 0.14 0.06 1.4e-04 2.4e-02 3.3e-04 1.7e-02
2 Brain gene expression Hnrnpul2 0.16 0.08 3.1e-09 0.12 0.07 0.11 -0 7.7e-11 4.5e-07 2.2e-10 6.8e-01
3 NAcc gene expression Hnrnpul2 0.1 0.06 1.2e-08 0.06 0.05 0.05 0.06 4.5e-09 5.4e-08 1.9e-08 3.2e-09
4 IC gene expression Hnrnpul2 0.15 0.1 4.6e-03 0.05 0.04 0.04 0.04 3.3e-03 1.3e-02 1.2e-02 1.3e-02
5 Liver gene expression Hnrnpul2 0.2 0.1 4.2e-12 0.1 0.09 0.09 0.09 5.1e-11 7.0e-10 3.4e-10 2.0e-10
6 OFC gene expression Hnrnpul2 0.38 0.17 5.0e-04 0.11 0.08 0.08 0 1.6e-03 6.1e-03 6.6e-03 2.7e-01
7 PL gene expression Hnrnpul2 0.16 0.08 3.9e-11 0.11 0.1 0.11 0.1 5.0e-12 1.2e-10 1.4e-11 2.3e-11
8 Adipose gene expression Hnrnpul2 0.2 0.09 1.4e-10 0.09 0.08 0.07 0.07 1.0e-09 5.8e-09 9.8e-09 1.1e-08
9 pVTA gene expression Hnrnpul2 0.14 0.07 6.0e-08 0.04 0.08 0.09 0.09 3.3e-04 4.8e-07 9.9e-08 2.2e-07
10 IL gene expression Hnrnpul2 0.17 0.1 6.3e-04 0.12 0.1 0.07 0.09 9.1e-04 2.8e-03 1.1e-02 4.1e-03
11 LHb mRNA stability Hnrnpul2 0.33 0.15 6.5e-04 0.07 0.02 0.02 0.04 1.2e-02 9.6e-02 1.3e-01 4.9e-02
12 Brain mRNA stability Hnrnpul2 0.08 0.05 1.4e-03 0.01 0.01 0 0 2.5e-02 2.7e-02 2.0e-01 1.5e-01
13 PL mRNA stability Hnrnpul2 0.1 0.06 1.6e-04 0.01 0.02 0.03 0.02 7.4e-03 1.0e-03 7.2e-04 1.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.30.52.0-0.5-0.50.5-0.6-0.7-0.7-0.7-0.30.10.7-0.4-1.4-0.9
Area under the delay curve0.40.61.0-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.40.10.7-1.0-0.2
BMI with tail1.13.920.4-1.6-1.61.6-1.6-1.6-1.6-1.6-1.60.22.80.0-4.5-1.4
BMI without tail0.21.14.0-0.9-0.90.9-1.0-0.9-0.9-0.9-1.0-0.01.11.2-2.00.0
Body weight0.62.514.80.40.4-0.30.30.30.30.30.11.83.80.1-3.70.1
Weight adjusted by age0.10.41.20.50.5-0.50.50.50.50.50.51.01.1-0.8-0.6-0.5
Bone surface0.40.94.30.20.2-0.20.20.10.10.10.41.12.1-1.5-1.8-0.5
Bone volume0.30.62.3-0.2-0.20.2-0.3-0.3-0.3-0.30.00.51.3-1.5-1.5-0.9
Breakpoint value in progressive ratio session2.24.05.52.32.3-2.32.32.32.32.32.22.21.7-1.00.50.0
Number of licking bursts0.00.11.10.10.1-0.0-0.00.10.10.1-0.10.00.2-0.1-0.21.1
Context. condit. distance diff. score1.62.03.8-1.5-1.51.5-1.6-1.6-1.6-1.6-1.3-0.9-0.81.0-0.8-1.9
Locomotion velocity, session 10.50.52.2-0.6-0.60.6-0.7-0.7-0.7-0.7-0.6-0.3-0.11.5-0.4-0.9
Locomotion distance, session 10.60.71.5-0.8-0.80.7-0.8-0.8-0.8-0.8-0.70.20.61.1-1.2-1.2
Locomotion velocity, session 20.50.62.80.50.5-0.50.60.60.60.60.51.21.7-0.1-1.2-0.3
Locomotion distance, session 20.10.10.7-0.1-0.10.1-0.1-0.0-0.0-0.0-0.10.40.30.9-0.4-0.6
Locomotion velocity, session 31.41.74.4-1.3-1.31.3-1.3-1.5-1.5-1.5-1.3-0.60.50.7-2.1-0.9
Locomotion distance, session 30.10.10.6-0.0-0.00.1-0.1-0.2-0.2-0.2-0.00.00.20.8-0.70.7
Stereotopy head waving bouts, day 32.73.34.4-2.0-2.02.0-1.9-2.1-2.1-2.1-1.9-1.3-0.60.3-1.9-2.1
Stereotopy head waving duration, day 31.51.93.9-1.5-1.51.5-1.4-1.6-1.6-1.6-1.5-0.9-0.50.5-0.9-2.0
Locomotion velocity, session 70.60.72.8-0.7-0.70.7-0.7-0.9-0.9-0.9-0.7-0.2-0.2-0.1-0.8-1.7
Locomotion distance, session 70.91.21.6-1.2-1.21.2-1.3-1.2-1.2-1.2-1.2-0.6-0.41.1-1.0-1.1
Stereotopy head waving bouts, day 70.10.21.0-0.2-0.20.2-0.1-0.2-0.2-0.2-0.1-0.00.4-1.0-0.4-0.7
Stereotopy head waving duration, day 70.40.52.00.60.6-0.60.70.60.60.60.60.91.4-0.8-0.40.1
Locomotion velocity, session 80.20.22.0-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.41.40.3-0.5
Locomotion distance, session 81.92.86.3-1.9-1.91.8-1.9-1.8-1.8-1.8-1.7-1.1-0.80.6-1.2-2.5
Degree of sensitization distance2.02.13.1-1.7-1.71.7-1.7-1.5-1.5-1.5-1.7-1.0-0.30.2-1.5-1.7
Degree of sensitization stereotypy0.50.51.90.60.6-0.60.70.60.60.60.70.71.1-1.4-0.2-0.2
Conditioned locomotion0.10.20.60.30.3-0.30.30.30.30.30.40.70.80.1-0.60.2
Cocaine response after cond. corrected1.01.52.9-1.4-1.41.3-1.3-1.2-1.2-1.2-1.2-1.1-1.11.7-0.2-1.3
Cocaine response after cond. not corrected0.60.91.4-1.1-1.11.0-1.1-0.9-0.9-0.9-0.9-0.9-0.81.2-0.2-0.7
Cocaine response before conditioning1.11.32.31.21.2-1.21.21.21.21.21.00.80.9-1.40.41.5
Saline control response1.41.94.01.31.3-1.21.41.41.41.41.21.92.00.7-0.51.6
Bone: connectivity density0.40.63.3-0.1-0.10.0-0.1-0.3-0.3-0.30.10.81.7-0.3-1.8-0.5
Bone: cortical apparent density0.71.11.51.11.1-1.11.21.21.21.21.21.20.5-0.21.00.3
Bone: cortical area0.30.51.70.60.6-0.50.60.50.50.50.40.91.3-1.1-0.80.5
Bone: cortical porosity0.60.71.11.01.0-1.00.80.90.90.91.00.7-0.2-0.41.1-0.4
Bone: cortical porosity0.60.60.90.90.9-1.00.80.90.90.90.90.80.1-0.10.9-0.2
Bone: cortical thickness3.76.18.82.72.7-2.72.72.72.72.72.63.02.40.30.62.6
Bone: cortical thickness0.70.91.90.90.9-0.91.00.90.90.90.91.10.71.10.51.4
Bone: cortical tissue density0.91.41.91.31.3-1.31.41.41.41.41.41.40.6-0.21.10.3
Condit. Reinf. active minus inactive responses0.40.51.50.70.7-0.70.60.60.60.60.70.81.2-0.3-0.40.3
Condit. Reinf. active-inactive response ratio0.50.50.80.90.9-0.90.80.70.70.70.90.90.80.10.50.2
Condit. Reinf. active responses0.30.31.40.30.3-0.30.20.20.20.20.20.51.2-1.0-1.0-0.4
Condit. Reinf. inactive responses0.50.71.6-0.8-0.80.8-0.7-0.7-0.7-0.7-0.8-0.70.1-1.2-1.3-1.0
Incentive salience index mean0.20.31.90.20.2-0.20.20.20.20.20.20.61.4-0.2-1.20.3
Condit. Reinf. lever presses0.20.32.0-0.2-0.20.3-0.2-0.1-0.1-0.1-0.30.31.2-0.3-1.40.3
Condit. Reinf. active minus inactive responses0.10.21.60.30.3-0.20.20.00.00.00.3-0.1-0.3-1.30.40.1
Condit. Reinf. active-inactive response ratio0.60.94.0-0.7-0.70.7-0.8-0.9-0.9-0.9-0.7-0.8-0.7-2.0-0.1-1.5
Condit. Reinf. active responses0.20.20.70.50.5-0.50.60.40.40.40.50.50.3-0.50.10.8
Condit. Reinf. inactive responses0.50.84.00.60.6-0.60.90.70.70.70.70.80.51.30.22.0
Condit. Reinf. lever presses0.40.51.60.50.5-0.50.60.60.60.60.50.71.3-0.9-0.71.1
Condit. Reinf. lever reinforcers received0.40.50.80.80.8-0.80.90.60.60.60.80.80.5-0.70.20.8
Conditioned reinforcement - actives0.10.54.7-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.5-0.4-2.20.1-1.1
Conditioned reinforcement - inactives0.51.33.8-1.0-1.01.1-1.1-1.2-1.2-1.2-1.1-1.0-0.1-1.9-0.9-1.3
Conditioned locomotion3.55.17.3-2.6-2.62.6-2.6-2.7-2.7-2.7-2.6-2.4-1.7-0.3-0.5-1.3
Patch foraging indifference point 0 sec0.10.20.90.30.3-0.40.3-0.1-0.1-0.10.40.60.90.2-0.7-0.3
Patch foraging indifference point AUC1.22.84.51.81.8-1.81.81.91.91.91.81.71.4-2.10.4-0.1
Delay disc. indifference point, 0s delay2.22.53.4-1.9-1.91.9-1.9-1.8-1.8-1.8-1.9-1.5-0.71.1-1.1-0.4
Delay disc. indifference point, 16s delay0.10.20.6-0.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.10.3-0.4-0.8-0.2
Delay disc. indifference point, 2s delay1.31.52.0-1.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.2-0.6-0.1-1.0-0.4
Delay disc. indifference point, 24s delay0.10.10.8-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.10.30.9-0.5-0.0
Delay disc. indifference point, 4s delay0.60.72.0-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.00.41.4-1.2-0.1
Delay disc. indifference point, 8s delay0.30.51.4-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.5-0.61.2-0.1-0.4
Indifference point function ln k2.36.910.4-2.9-2.92.8-2.9-2.9-2.9-2.9-2.8-2.8-2.43.2-0.4-0.3
Indifference point function log k2.36.910.4-2.9-2.92.8-2.9-2.9-2.9-2.9-2.8-2.8-2.43.2-0.4-0.3
Patch foraging total patch changes 0 sec0.10.30.90.60.6-0.60.60.20.20.20.70.81.00.7-0.40.2
Patch foraging total patch changes 12 sec4.15.49.82.62.6-2.62.62.42.42.42.63.12.9-1.1-0.4-0.2
Patch foraging total patch changes 18 sec0.41.11.91.11.1-1.11.21.01.01.01.31.40.9-0.90.2-0.0
Patch foraging total patch changes 24 sec0.82.89.01.61.6-1.61.61.41.41.41.72.43.0-0.4-1.50.5
Patch foraging total patch changes 6 sec0.30.52.00.60.6-0.60.50.30.30.30.71.11.40.2-1.00.0
Patch foraging time to switch 0 sec0.20.61.8-0.6-0.60.6-0.5-0.6-0.6-0.6-0.50.00.6-1.1-1.4-1.2
Patch foraging water rate 0 sec0.10.30.90.00.0-0.0-0.2-0.2-0.2-0.20.0-0.4-0.81.00.80.8
Patch foraging water rate 12 sec0.41.86.0-1.1-1.11.1-1.1-1.1-1.1-1.1-1.3-1.6-1.72.50.71.1
Patch foraging water rate 18 sec0.81.97.4-1.3-1.31.3-1.4-1.3-1.3-1.3-1.3-1.2-0.82.7-0.50.8
Patch foraging water rate 24 sec0.71.02.4-0.9-0.90.9-1.1-0.9-0.9-0.9-0.9-1.2-1.51.60.60.2
Patch foraging water rate 6 sec0.91.35.3-1.0-1.01.0-0.9-0.9-0.9-0.9-1.1-1.0-1.52.30.61.2
Seeking ratio, delayed vs. immediate footshock0.10.10.4-0.2-0.20.2-0.2-0.3-0.3-0.3-0.2-0.30.20.3-0.60.6
Distance traveled before self-admin0.51.13.10.90.9-0.90.90.90.90.90.81.31.8-1.5-1.0-0.1
Distance traveled after self-admin0.81.31.91.41.4-1.41.41.31.31.31.41.10.9-0.70.40.2
Extensor digitorum longus weight2.07.829.12.62.6-2.52.42.42.42.42.43.75.4-0.2-2.51.8
Bone: elastic displacement0.20.31.10.30.3-0.30.30.30.30.30.40.1-0.71.10.80.6
Bone: elastic work0.60.81.80.80.8-0.80.80.70.70.70.91.31.01.4-0.31.0
Bone: endosteal estimation3.48.210.9-3.2-3.23.2-3.2-3.3-3.3-3.3-3.2-2.8-1.4-0.7-2.5-2.5
Bone: endosteal perimeter3.58.610.8-3.2-3.23.2-3.2-3.2-3.2-3.2-3.3-3.1-1.7-1.7-2.1-2.8
Epididymis fat weight1.05.27.4-2.7-2.72.7-2.6-2.4-2.4-2.4-2.5-2.5-1.4-1.4-1.5-1.2
Delta time in closed arm before/after self-admin0.60.55.0-0.1-0.10.1-0.1-0.1-0.1-0.1-0.20.80.82.2-0.80.1
Delta time in open arm before/after self-admin1.31.54.21.21.2-1.21.21.11.11.11.31.31.5-2.1-0.4-0.7
Diff in mean of infusions in LGA sessions1.42.53.61.81.8-1.81.81.81.81.81.81.91.70.1-0.10.1
Delay discount exponential model param0.40.50.90.80.8-0.80.80.80.80.80.80.3-0.1-0.71.00.2
Extinction: sum of active levers before priming1.01.54.71.21.2-1.11.21.11.11.11.11.72.2-0.6-1.00.2
Active lever presses in extinction session 62.42.43.31.71.7-1.71.71.71.71.71.61.71.8-1.7-0.3-0.1
Bone: final force0.30.52.90.30.3-0.20.20.20.20.20.20.91.7-0.7-1.30.1
Bone: final moment0.30.53.10.30.3-0.30.30.30.30.30.31.01.8-0.6-1.40.2
Food consumed during 24 hour testing period0.10.21.10.30.3-0.30.20.20.20.20.4-0.0-0.1-0.50.21.1
Glucose3.45.37.5-2.6-2.62.6-2.5-2.7-2.7-2.7-2.5-2.6-2.00.5-1.1-1.4
Heart weight2.64.25.8-2.4-2.42.4-2.3-2.4-2.4-2.4-2.3-1.8-0.61.7-1.8-0.6
Delay discount hyperbolic model param0.50.61.00.90.9-0.90.90.90.90.90.90.5-0.0-0.61.00.2
Intermittent access intake day 1-15 change0.10.73.4-0.4-0.40.4-0.4-0.2-0.2-0.2-0.4-1.2-1.5-1.81.1-0.1
Intermittent access intake escalation0.20.84.2-0.4-0.40.4-0.4-0.2-0.2-0.2-0.4-1.3-1.7-2.01.3-0.2
Intermittent access intake escalation 20.30.54.2-0.2-0.20.2-0.20.10.10.1-0.2-0.7-0.8-2.00.7-0.3
Intermitt. access day 1 inactive lever presses0.00.41.5-0.2-0.20.2-0.2-0.2-0.2-0.2-0.3-0.7-1.2-1.01.0-0.7
Intermitt. access day 15 inactive lever presses0.20.94.3-0.7-0.70.7-0.6-0.6-0.6-0.6-0.8-0.50.9-2.1-1.5-0.3
Intermitt. access escalation Index0.10.41.0-0.6-0.60.6-0.6-0.7-0.7-0.7-0.5-0.8-1.01.00.50.3
Intermittent access day 1 total infusions3.510.615.5-3.8-3.83.8-3.8-3.9-3.9-3.9-3.9-2.7-0.6-0.4-2.8-1.1
Intermittent access day 15 total infusions3.27.710.6-3.2-3.23.2-3.2-3.1-3.1-3.1-3.2-3.3-2.1-1.8-0.8-0.9
Intermittent access terminal intake (last 3 days)4.57.810.6-3.2-3.23.3-3.3-3.2-3.2-3.2-3.3-2.7-1.1-2.1-1.9-1.3
Intermittent access total infusions7.18.411.8-3.4-3.43.4-3.4-3.4-3.4-3.4-3.4-2.7-1.1-1.2-2.1-1.1
Intermittent access day 1 locomotion3.15.78.3-2.8-2.82.8-2.8-2.9-2.9-2.9-2.9-1.6-0.2-0.1-2.3-1.2
Intermittent access day 15 total locomotion1.14.15.5-2.2-2.22.2-2.3-2.3-2.3-2.3-2.3-1.7-0.4-1.9-1.5-1.7
Intermittent access total locomotion8.510.214.0-3.7-3.73.7-3.7-3.7-3.7-3.7-3.7-2.5-0.4-2.1-2.7-2.2
Intermittent access standard deviation0.10.71.2-0.8-0.80.9-0.8-0.7-0.7-0.7-0.9-1.1-1.1-1.10.3-0.3
Left kidney weight0.43.14.3-2.1-2.12.0-2.0-2.0-2.0-2.0-1.9-1.6-0.6-0.7-1.5-1.8
Right kidney weight0.21.32.0-1.4-1.41.4-1.3-1.2-1.2-1.2-1.3-1.1-0.4-0.8-1.0-0.7
Cocaine induced anxiety0.20.41.10.70.7-0.70.70.70.70.70.70.50.1-1.10.5-0.6
Post-drug Anxiety0.30.40.50.70.7-0.70.70.70.70.70.70.50.6-0.70.1-0.2
Baseline Anxiety0.10.21.60.10.1-0.10.10.10.10.10.20.30.61.3-0.40.9
Tail length0.52.54.71.81.8-1.71.61.61.61.61.61.61.10.90.62.2
Length with tail0.94.26.82.22.2-2.22.12.22.22.22.02.42.60.2-0.52.0
Length without tail0.84.410.42.12.1-2.12.12.22.22.21.92.73.20.4-1.31.4
Times rat made contact with spout0.50.61.80.80.8-0.80.70.70.70.70.70.80.30.90.41.4
Lifetime Intake5.77.110.4-3.2-3.23.2-3.2-3.1-3.1-3.1-3.2-2.4-1.0-0.4-1.9-0.6
Liver weight, left0.30.51.7-0.7-0.70.7-0.6-0.5-0.5-0.5-0.6-1.1-1.30.40.40.1
Liver weight, right1.83.14.1-2.0-2.02.0-2.0-1.9-1.9-1.9-1.9-1.9-1.61.6-0.90.0
Locomotor activity0.40.64.8-0.2-0.20.3-0.3-0.5-0.5-0.5-0.4-0.6-1.02.20.70.6
Locomotor testing distance0.51.36.7-0.8-0.80.8-0.9-1.1-1.1-1.1-0.9-0.9-1.22.60.30.6
Locomotor testing rearing0.31.04.0-0.8-0.80.8-0.9-1.0-1.0-1.0-0.9-1.0-1.42.00.20.7
Locomotion in novel chamber2.02.63.5-1.8-1.81.8-1.8-1.9-1.9-1.9-1.8-1.8-1.6-0.7-0.1-1.3
Locomotion in novel chamber post-restriction0.41.33.5-1.0-1.01.0-1.0-0.9-0.9-0.9-1.1-1.3-1.9-0.90.7-1.4
Fecal boli incidents, locomotor time 10.10.33.00.10.1-0.10.10.00.00.00.1-0.5-0.4-1.70.3-0.1
Change in fecal boli incidents, locomotor task1.41.52.7-1.3-1.31.3-1.3-1.4-1.4-1.4-1.3-1.2-1.21.60.0-0.3
Time >=10cm from walls, locomotor time 11.92.43.7-1.6-1.61.6-1.6-1.7-1.7-1.7-1.5-1.9-1.2-1.8-0.3-1.4
Bouts of movement, locomotor time 13.84.97.12.72.7-2.72.72.52.52.52.71.80.6-0.92.2-0.2
Total resting periods, locomotor time 13.23.65.22.32.3-2.32.32.22.22.22.31.50.5-1.21.8-0.2
Rest time, locomotor task time 10.30.42.4-0.3-0.30.3-0.3-0.1-0.1-0.1-0.3-0.9-1.5-0.41.10.6
Distance moved, locomotor task time 10.10.20.8-0.3-0.30.3-0.3-0.4-0.4-0.4-0.3-0.00.60.2-0.90.1
Vertical activity count, locomotor time 10.10.50.8-0.8-0.80.8-0.8-0.9-0.9-0.9-0.8-0.9-0.70.4-0.1-0.5
Time >=10cm from walls, locomotor time 20.20.52.70.70.7-0.60.70.60.60.60.60.10.0-1.60.8-0.3
Bouts of movement, locomotor time 20.41.31.81.31.3-1.31.31.31.31.31.31.41.3-0.30.00.8
Total resting periods, locomotor time 20.20.70.90.90.9-0.90.91.01.01.00.91.00.8-0.40.10.5
Rest time, locomotor task time 21.01.84.3-1.4-1.41.4-1.4-1.3-1.3-1.3-1.4-1.7-2.10.20.6-0.4
Distance moved, locomotor task time 21.11.52.11.41.4-1.41.41.41.41.41.41.20.9-0.20.60.6
Vertical activity count, locomotor time 20.30.71.01.01.0-1.01.00.90.90.91.00.7-0.00.90.90.5
Light reinforcement 10.10.42.10.40.4-0.40.70.50.50.50.4-0.1-0.1-0.00.81.5
Light reinforcement 20.30.75.4-0.6-0.60.6-0.5-0.4-0.4-0.4-0.6-0.9-0.3-2.3-0.2-0.5
Bone: marrow area3.58.711.5-3.3-3.33.3-3.3-3.4-3.4-3.4-3.2-3.0-1.6-0.6-2.4-2.5
Bone: maximum diameter0.30.62.5-0.5-0.50.6-0.5-0.5-0.5-0.5-0.7-0.20.5-1.6-1.1-0.9
Bone: maximum force0.51.16.0-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.82.2-1.3-2.4-0.4
Bone: maximum moment0.51.05.9-0.1-0.10.1-0.1-0.2-0.2-0.2-0.10.92.2-1.2-2.4-0.2
Mean time between licks in bursts0.10.54.60.10.1-0.10.10.30.30.3-0.00.40.72.1-0.51.0
Mean num. licks in bursts0.10.10.40.30.3-0.40.30.20.20.20.50.3-0.30.70.6-0.3
Cd content in liver0.70.82.8-0.8-0.80.7-0.9-0.9-0.9-0.9-0.6-0.8-0.9-1.00.4-1.7
Co content in liver0.60.72.50.40.4-0.40.50.50.50.50.5-0.0-1.01.61.60.9
Cu content in liver0.10.10.20.40.4-0.40.30.30.30.30.40.3-0.10.40.4-0.1
Fe content in liver0.10.10.2-0.4-0.40.4-0.3-0.3-0.3-0.3-0.3-0.2-0.20.2-0.2-0.5
K content in liver0.20.21.3-0.2-0.20.2-0.1-0.1-0.1-0.1-0.30.20.60.2-1.10.9
Mg content in liver0.60.71.7-0.8-0.80.9-0.9-0.9-0.9-0.9-0.9-0.50.01.0-1.30.1
Mn content in liver1.51.74.21.31.3-1.31.31.21.21.21.21.72.1-1.1-0.80.9
Na content in liver0.10.10.60.20.2-0.20.30.20.20.20.00.30.6-0.3-0.60.7
Rb content in liver1.41.73.8-1.3-1.31.3-1.2-1.2-1.2-1.2-1.4-1.8-1.91.40.10.2
Se content in liver0.10.21.60.10.1-0.0-0.1-0.0-0.0-0.0-0.00.10.3-1.3-0.5-0.5
Sr content in liver2.52.24.21.51.5-1.51.61.61.61.61.52.02.0-0.8-0.10.8
Zn content in liver0.70.93.30.80.8-0.80.80.70.70.70.81.51.8-0.1-1.0-0.4
Bone: minimum diameter2.75.16.6-2.5-2.52.5-2.5-2.6-2.6-2.6-2.5-2.2-0.8-1.0-2.3-1.8
Time in familiar zone, hab. session 10.10.10.7-0.3-0.30.3-0.3-0.4-0.4-0.4-0.2-0.10.30.2-0.80.0
Time in novel zone, hab. session 10.40.41.6-0.4-0.40.4-0.5-0.4-0.4-0.4-0.4-0.8-1.30.90.80.3
Total zone transitions, hab. session 10.10.10.30.30.3-0.30.40.50.50.50.30.50.50.10.2-0.1
Total locomotion distance, hab. session 10.71.02.9-1.1-1.11.1-1.1-1.0-1.0-1.0-1.1-0.7-0.3-0.5-0.9-1.7
Locomotion velocity, hab. session 10.20.31.7-0.5-0.50.5-0.4-0.3-0.3-0.3-0.50.00.3-0.6-0.7-1.3
Time in familiar zone, hab. session 20.50.52.70.60.6-0.60.60.50.50.50.7-0.0-0.41.10.51.6
Time in novel zone, hab. session 20.30.30.9-0.5-0.50.5-0.5-0.5-0.5-0.5-0.60.10.6-0.3-0.8-0.9
Total zone transitions, hab. session 20.30.42.0-0.0-0.00.0-0.0-0.1-0.1-0.10.00.61.30.8-1.40.1
Total locomotion distance, hab. session 20.50.62.2-0.8-0.80.8-0.7-0.8-0.8-0.8-0.8-0.20.30.5-1.5-0.8
Locomotion velocity, hab. session 20.70.92.2-1.0-1.01.0-1.0-1.0-1.0-1.0-1.0-0.50.10.1-1.5-1.2
Novel to familiar place preference ratio0.60.82.60.70.7-0.70.80.80.80.80.71.11.6-1.2-0.50.0
Novelty place preference0.40.51.60.60.6-0.60.60.60.60.60.50.81.3-1.1-0.3-0.0
Time in novel zone, NPP test0.40.41.70.50.5-0.50.50.60.60.60.50.81.3-0.9-0.5-0.0
Total zone transitions, NPP test0.20.31.30.30.3-0.30.40.30.30.30.41.11.10.6-0.6-0.5
Total locomotion distance, NPP test0.30.51.4-0.6-0.60.6-0.6-0.7-0.7-0.7-0.6-0.00.00.7-0.9-1.2
Locomotion velocity, NPP test0.20.31.4-0.5-0.50.5-0.4-0.5-0.5-0.5-0.40.0-0.10.5-0.5-1.2
Intraocular pressure0.40.61.90.90.9-0.80.70.70.70.70.80.2-0.3-0.51.40.5
Delta distance traveled before/after self-admin0.30.32.20.30.3-0.30.20.20.20.20.3-0.2-0.61.50.90.4
Delta ambulatory time before/after self-admin0.20.42.20.20.2-0.20.20.20.20.20.2-0.4-0.91.51.10.6
Parametrial fat weight3.07.09.0-3.0-3.03.0-3.0-2.9-2.9-2.9-2.9-2.9-1.7-1.4-1.5-2.3
Pavlov. Cond. lever latency0.30.32.30.10.1-0.10.1-0.1-0.1-0.10.1-0.5-1.20.41.5-0.2
Pavlov. Cond. magazine entry latency0.40.52.40.00.0-0.00.00.10.10.10.10.51.3-1.4-1.5-0.0
Pavlov. Cond. change in total contacts0.30.43.10.10.1-0.10.10.10.10.10.10.40.7-1.8-0.9-0.3
Pavlov. Cond. index score0.30.41.20.40.4-0.40.40.50.50.50.40.71.1-1.1-0.90.5
Pavlov. Cond. latency score0.20.31.20.10.1-0.10.10.20.20.20.10.51.0-0.7-1.10.4
Pavlov. Cond. lever contacts0.20.32.3-0.3-0.30.3-0.3-0.2-0.2-0.2-0.30.20.8-0.3-1.50.3
Pavlov. Cond. magazine entry number0.70.91.9-0.9-0.90.9-0.9-1.0-1.0-1.0-1.0-1.1-1.21.40.3-0.5
Pavlov. Cond. intertrial magazine entries0.70.91.21.11.1-1.11.01.01.01.01.10.80.2-1.10.9-0.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.70.40.4-0.40.40.50.50.50.50.71.1-1.3-1.00.3
Pavlov. Cond. response bias0.40.61.60.50.5-0.50.50.60.60.60.50.81.2-1.3-0.90.4
Pavlov. Cond. lever latency0.20.20.9-0.3-0.30.3-0.3-0.4-0.4-0.4-0.3-0.4-1.00.60.7-0.6
Pavlov. Cond. magazine entry latency2.53.57.21.91.9-2.01.92.02.02.02.02.42.7-1.0-0.60.8
Pavlov. Cond. change in total contacts0.51.22.91.01.0-1.01.01.01.01.01.01.11.6-1.7-0.60.6
Pavlov. Cond. index score1.11.74.41.21.2-1.21.21.31.31.31.31.52.1-1.5-0.80.7
Pavlov. Cond. latency score0.91.43.81.01.0-1.01.01.11.11.11.11.42.0-1.6-0.90.4
Pavlov. Cond. lever contacts0.20.30.80.50.5-0.50.50.60.60.60.50.50.9-0.7-0.40.7
Pavlov. Cond. magazine entry number4.05.210.9-2.3-2.32.4-2.3-2.4-2.4-2.4-2.4-2.9-3.31.50.8-0.9
Pavlov. Cond. intertrial magazine entries0.30.62.7-0.7-0.70.7-0.5-0.5-0.5-0.5-0.6-1.0-1.6-0.31.1-0.5
Pavlov. Cond. lever-magazine prob. diff.1.42.15.01.41.4-1.41.41.51.51.51.41.72.2-1.5-0.80.8
Pavlov. Cond. response bias0.91.23.51.01.0-1.01.01.11.11.11.01.21.9-0.8-0.81.0
Time in closed arm before self-admin0.10.21.8-0.4-0.40.4-0.4-0.3-0.3-0.3-0.3-0.6-0.1-1.4-0.30.2
Time in closed arm after self-admin0.70.81.2-1.0-1.01.0-1.0-0.9-0.9-0.9-1.0-1.1-1.00.9-0.00.6
Time in open arm before self-admin1.01.39.7-0.7-0.70.8-0.7-0.8-0.8-0.8-0.9-0.5-1.13.10.50.5
Time in open arm after self-admin0.50.61.60.80.8-0.80.80.70.70.70.81.30.70.60.3-0.6
Bone: periosteal estimation1.12.54.5-1.6-1.61.7-1.7-1.8-1.8-1.8-1.7-1.20.0-1.4-2.1-1.4
Bone: periosteal perimeter0.51.02.2-1.0-1.01.0-0.9-0.9-0.9-0.9-1.1-0.80.1-1.5-1.3-0.7
Bone: post-yield work2.95.07.0-2.4-2.42.4-2.4-2.4-2.4-2.4-2.3-1.7-0.1-1.8-2.5-2.7
Progressive ratio test 1 active lever presses0.91.52.1-1.4-1.41.4-1.4-1.5-1.5-1.5-1.4-1.1-0.6-0.4-0.5-1.1
Progressive ratio test 1 breakpoint0.81.52.0-1.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.1-0.6-0.6-0.5-1.1
Progressive ratio test 1 inactive lever presses0.10.21.2-0.3-0.30.3-0.2-0.2-0.2-0.2-0.40.20.9-0.5-1.1-0.2
Progressive ratio test 2 active lever presses2.33.24.2-2.0-2.02.0-2.0-2.0-2.0-2.0-2.1-1.8-0.9-1.6-0.8-1.3
Progressive ratio test 2 breakpoint2.53.24.2-2.0-2.02.0-2.0-2.0-2.0-2.0-2.1-1.8-0.9-1.6-0.9-1.3
Progressive ratio test 2 inactive lever presses1.03.24.2-2.0-2.02.0-2.0-2.0-2.0-2.0-2.0-1.8-0.7-1.9-1.1-1.3
Incentive Sensitization - Responses0.30.82.4-0.8-0.80.8-0.8-0.7-0.7-0.7-0.8-0.30.8-1.5-1.5-0.7
Incentive Sensitization - Breakpoint0.41.02.6-0.9-0.90.9-0.9-0.8-0.8-0.8-1.0-0.50.7-1.6-1.5-0.8
Sum of active levers in priming session hrs 5-64.74.57.32.42.4-2.42.42.42.42.42.31.61.1-2.71.2-0.1
Progressive ratio0.41.11.6-1.2-1.21.2-1.2-1.1-1.1-1.1-1.2-0.90.1-0.8-1.30.1
Food seeking constrained by brief footshock0.10.20.3-0.3-0.30.3-0.4-0.4-0.4-0.4-0.4-0.6-0.20.6-0.30.6
Seeking ratio, punishment vs. effort0.10.33.00.20.2-0.20.20.10.10.10.20.1-0.31.70.40.1
Retroperitoneal fat weight3.515.622.4-4.6-4.64.6-4.5-4.3-4.3-4.3-4.3-4.7-4.20.6-0.7-2.0
Reaction time number correct0.31.14.91.11.1-1.00.90.90.90.90.80.80.90.70.12.2
Reaction time mean minus median0.42.36.01.61.6-1.61.71.71.71.71.51.20.8-2.40.9-0.6
Reaction time mean minus median AUC0.42.43.51.81.8-1.81.91.81.81.81.61.20.4-1.51.40.1
Reaction time num false alarms0.30.44.7-0.0-0.00.0-0.1-0.1-0.1-0.10.10.1-0.72.20.7-0.1
Reaction time num false alarms AUC0.30.64.80.60.6-0.60.50.40.40.40.70.7-0.12.20.80.1
Reaction time trials correct on left0.31.14.91.11.1-1.00.90.90.90.90.80.80.90.70.12.2
Reaction time trials on left0.41.25.01.11.1-1.11.01.01.01.00.90.80.90.70.12.2
Reaction time mean0.30.62.30.60.6-0.60.70.60.60.60.70.3-0.2-1.50.9-1.1
Reaction time mean AUC0.20.52.30.50.5-0.60.60.50.50.50.60.1-0.2-1.50.9-0.6
Median of all reaction times0.10.21.00.10.1-0.20.20.20.20.20.30.1-0.2-1.00.5-1.0
Reaction time omissions1.01.72.61.51.5-1.51.61.51.51.51.51.20.5-0.81.10.1
Reaction time false alarm rate0.30.42.5-0.4-0.40.3-0.3-0.4-0.4-0.4-0.1-0.0-0.71.60.4-1.2
Reaction time premature initiation rate1.01.66.00.60.6-0.60.70.80.80.80.51.62.51.6-1.81.7
Reaction time premature initiations1.23.68.51.61.6-1.61.61.71.71.71.42.32.91.7-1.12.9
Std. dev. reaction times0.51.63.11.31.3-1.31.41.31.31.31.30.8-0.2-1.81.6-1.0
Reaction time trials completed0.41.25.01.11.1-1.11.01.01.01.00.90.80.90.70.12.2
Reaction time trials AUC0.30.94.80.90.9-0.90.80.70.70.70.70.70.80.80.02.2
Run reversals in cocaine runway, females1.51.63.7-1.3-1.31.3-1.3-1.3-1.3-1.3-1.3-0.40.61.9-1.70.2
Run reversals in cocaine runway, males0.10.10.60.10.1-0.10.1-0.0-0.0-0.00.0-0.3-0.70.30.7-0.2
Latency to leave start box in cocaine runway1.41.93.0-1.7-1.71.7-1.7-1.5-1.5-1.5-1.6-1.6-0.6-0.2-0.8-0.6
Latency to leave start box in cocaine runway, F0.10.20.3-0.6-0.60.6-0.6-0.3-0.3-0.3-0.6-0.40.2-0.1-0.5-0.1
Latency to leave start box in cocaine runway, M2.52.43.4-1.8-1.81.8-1.8-1.7-1.7-1.7-1.7-1.8-1.50.0-0.3-0.9
Std. dev. time between licks in bursts0.20.43.4-0.4-0.40.4-0.3-0.2-0.2-0.2-0.4-0.4-0.21.8-0.00.9
Total sessions with >9 infusions1.82.23.2-1.8-1.81.8-1.8-1.7-1.7-1.7-1.8-1.5-1.00.1-0.7-0.4
Short access day 1 total inactive lever presses0.91.83.0-1.5-1.51.5-1.5-1.7-1.7-1.7-1.6-0.8-0.10.4-1.0-0.8
Short access day 10 total inactive lever presses0.00.10.7-0.2-0.20.2-0.2-0.3-0.3-0.3-0.3-0.4-0.80.50.6-0.1
Short access day 1 total infusions1.93.75.4-2.3-2.32.3-2.3-2.2-2.2-2.2-2.3-2.0-1.40.4-0.90.2
Short access day 10 total infusions3.65.99.0-2.9-2.92.9-2.9-2.9-2.9-2.9-3.0-2.1-0.5-0.2-2.1-0.5
Short access total infusions3.95.58.3-2.8-2.82.9-2.9-2.7-2.7-2.7-2.9-2.1-0.90.7-1.7-0.0
Short access day 1 locomotion1.01.72.5-1.6-1.61.6-1.6-1.6-1.6-1.6-1.6-1.0-0.6-0.3-0.9-0.5
Short access day 10 total locomotion0.72.74.0-1.9-1.91.9-1.9-1.8-1.8-1.8-2.0-1.10.1-0.8-1.7-1.0
Short access total locomotion2.03.04.3-2.1-2.12.1-2.1-2.0-2.0-2.0-2.1-1.3-0.3-0.6-1.5-1.0
One hour access (0.3 mA shock)4.04.76.9-2.6-2.62.6-2.6-2.5-2.5-2.5-2.6-2.2-1.2-1.0-1.3-0.7
Compulsive drug intake2.13.14.12.02.0-2.02.02.02.02.01.91.90.91.60.61.4
One hour access (shock baseline)3.07.810.5-3.2-3.23.2-3.2-3.1-3.1-3.1-3.2-3.1-2.1-1.9-0.7-1.4
Social response proportion0.20.32.80.10.1-0.10.20.30.30.30.00.00.20.4-0.01.7
Social responses0.91.13.91.11.1-1.11.21.01.01.01.10.90.20.50.72.0
Social time0.50.81.40.90.9-0.91.01.01.01.00.70.5-0.20.70.91.2
Soleus weight1.23.69.1-1.8-1.81.8-2.0-1.9-1.9-1.9-1.8-2.7-3.00.80.9-0.9
Bone: stiffness0.20.42.90.30.3-0.30.20.20.20.20.20.41.2-1.7-0.90.2
Tibialis anterior weight4.214.634.14.04.0-4.03.93.83.83.83.95.15.8-1.3-1.51.6
Time to tail flick, vehicle, before self-admin0.80.92.0-1.0-1.01.0-1.1-1.0-1.0-1.0-1.1-0.40.3-0.5-1.4-1.0
Time to tail flick, vehicle, after self-admin0.20.51.4-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.30.50.7-1.20.3
Time to tail flick, test, before self-admin2.12.44.4-1.7-1.71.7-1.7-1.8-1.8-1.8-1.7-0.60.51.0-2.1-0.9
Time to tail flick, test, after self-admin0.10.20.80.30.3-0.30.30.40.40.40.30.40.2-0.90.1-0.0
Delta time to tail flick, vehicle, before/after SA0.10.10.60.20.2-0.20.30.20.20.20.30.30.40.8-0.10.7
Delta time to tail flick, test, before/after SA2.93.54.92.22.2-2.22.12.22.22.22.11.20.1-1.62.00.6
Tibia length0.82.18.11.31.3-1.31.31.11.11.11.11.62.2-2.9-0.7-0.7
Ambulatory time before self-admin0.41.33.61.01.0-1.01.11.01.01.01.01.21.6-1.9-0.7-0.3
Ambulatory time after self-admin0.20.30.80.60.6-0.60.60.50.50.50.60.30.6-0.9-0.1-0.0
Bone: tissue strength0.20.22.0-0.1-0.10.2-0.1-0.0-0.0-0.0-0.3-0.5-0.50.60.41.4
Total heroin consumption6.98.111.93.33.3-3.33.33.33.33.33.13.42.7-0.80.40.4
Bone: trabecular number0.30.63.1-0.3-0.30.3-0.4-0.6-0.6-0.6-0.20.41.4-0.5-1.8-0.6
Bone: trabecular spacing0.50.72.80.40.4-0.40.50.70.70.70.3-0.1-0.91.21.21.7
Bone: trabecular thickness0.20.31.1-0.4-0.40.4-0.5-0.5-0.5-0.5-0.3-0.5-0.3-1.0-0.2-1.0
Bone: trabecular tissue density1.01.88.9-0.9-0.90.9-0.8-0.5-0.5-0.5-1.0-1.8-3.00.32.4-0.7
Water consumed over 24 hours0.61.23.71.21.2-1.11.01.11.11.11.01.11.00.50.21.9
Number of responses in last shaping day0.10.11.10.20.2-0.20.20.20.20.20.10.60.31.0-0.30.2