Hub : Genes

Zdhhc24

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL isoform ratio XM_063286824.1 0.14 0.1 8.0e-03 0.04 0.11 0.04 0.06 4.1e-02 1.4e-03 3.7e-02 1.5e-02
2 PL isoform ratio NM_001039100.1 0.1 0.07 1.7e-05 0.04 0.05 0.03 0.04 1.5e-05 4.7e-06 1.9e-04 1.8e-05
3 OFC alternative polyA NM_001039100.1 0.14 0.11 5.3e-03 0.1 0.1 0.08 0.08 2.2e-03 2.2e-03 7.5e-03 6.0e-03
4 PL isoform ratio XM_063286824.1 0.09 0.07 1.8e-05 0.05 0.05 0.03 0.04 7.9e-06 4.2e-06 2.1e-04 1.2e-05
5 IL alternative polyA XM_063286824.1 0.13 0.09 9.6e-03 0.04 0.04 0.03 0.02 3.7e-02 3.1e-02 6.8e-02 1.1e-01
6 IL alternative polyA NM_001039100.1 0.16 0.1 3.4e-03 0.03 0.05 0.04 0.03 5.5e-02 2.3e-02 3.1e-02 7.2e-02
7 PL alternative polyA XM_063286824.1 0.05 0.03 5.7e-05 0.03 0.04 0.03 0.03 7.0e-04 6.6e-05 2.6e-04 1.4e-04
8 OFC alternative polyA XM_063286824.1 0.13 0.1 8.0e-03 0.09 0.09 0.05 0.07 3.2e-03 3.6e-03 2.6e-02 9.2e-03
9 PL alternative polyA NM_001039100.1 0.05 0.04 2.3e-05 0.03 0.04 0.04 0.03 4.5e-04 6.1e-05 8.0e-05 1.7e-04
10 Liver gene expression Zdhhc24 0.12 0.07 6.5e-08 0.06 0.05 0.06 0.05 7.3e-07 1.5e-06 5.7e-07 1.5e-06
11 Eye gene expression Zdhhc24 0.4 0.16 5.0e-04 0 0.04 0.07 0.03 3.2e-01 8.4e-02 3.2e-02 1.3e-01
12 BLA alternative polyA NM_001039100.1 0.05 0.04 9.3e-03 0.03 0.02 0.01 0.02 1.4e-02 2.9e-02 6.8e-02 2.6e-02
13 BLA alternative polyA XM_063286824.1 0.06 0.04 6.7e-03 0.03 0.02 0.01 0.03 9.5e-03 2.0e-02 5.3e-02 1.3e-02
14 PL gene expression Zdhhc24 0.14 0.08 3.7e-15 0.14 0.14 0.14 0.14 2.9e-15 6.2e-15 1.0e-14 9.5e-15
15 IC gene expression Zdhhc24 0.18 0.14 1.0e-04 0.1 0.1 0.1 0.1 7.2e-05 6.2e-05 5.3e-05 4.4e-05
16 BLA mRNA stability Zdhhc24 0.09 0.06 6.6e-04 0.06 0.05 0.05 0.04 3.4e-04 1.5e-03 1.7e-03 2.7e-03
17 NAcc gene expression Zdhhc24 0.09 0.05 0.0e+00 0.12 0.12 0.11 0.12 3.3e-18 6.8e-18 4.5e-16 1.1e-17
18 Adipose isoform ratio NM_001039100.1 0.05 0.06 9.6e-03 0.03 0.01 0.02 0.03 4.4e-04 1.1e-02 1.2e-03 7.2e-04
19 Adipose isoform ratio XM_063286824.1 0.05 0.06 8.2e-03 0.03 0.01 0.02 0.03 4.0e-04 9.2e-03 9.9e-04 6.6e-04
20 BLA gene expression Zdhhc24 0.18 0.1 1.6e-07 0.07 0.12 0.11 0.11 1.2e-04 9.8e-07 1.5e-06 2.3e-06
21 IC mRNA stability Zdhhc24 0.1 0.07 2.8e-03 0.01 0.05 0.04 0.04 1.8e-01 4.2e-03 8.8e-03 1.3e-02
22 Brain gene expression Zdhhc24 0.2 0.1 8.3e-16 0.14 0.17 0.17 0.18 2.4e-13 6.0e-16 5.4e-16 2.1e-16
23 pVTA gene expression Zdhhc24 0.21 0.1 6.7e-16 0.15 0.19 0.19 0.19 5.0e-12 2.6e-15 6.0e-15 6.3e-15
24 NAcc mRNA stability Zdhhc24 0.02 0.01 5.6e-03 0.01 0.01 0.01 0.01 1.5e-02 2.1e-03 9.2e-03 5.7e-03
25 RMTg gene expression Zdhhc24 0.19 0.14 1.7e-03 0.11 0.08 0.14 0.09 6.9e-04 3.5e-03 1.3e-04 1.8e-03
26 Brain mRNA stability Zdhhc24 0.07 0.04 2.4e-06 0.03 0.07 0.06 0.06 4.4e-04 1.0e-06 1.1e-06 3.3e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density1.52.57.1-1.50.91.0-0.8-0.60.4-0.3-0.70.3-2.10.1-1.51.5-1.5-1.3-1.3-1.3-2.72.7-2.1-2.1-1.9-2.2-2.3-0.9-2.4
Area under the delay curve0.70.81.7-0.0-0.6-0.30.60.4-0.50.60.4-0.7-0.40.9-1.31.3-1.0-1.1-0.8-0.7-1.21.2-1.1-1.1-0.8-1.1-1.11.0-1.1
BMI with tail1.86.220.2-3.32.12.4-2.1-2.01.7-1.5-2.31.4-4.2-0.4-1.21.2-1.3-1.1-1.3-1.1-4.54.5-2.8-2.8-2.6-2.9-3.2-0.5-3.4
BMI without tail0.72.38.7-2.21.11.6-1.1-1.51.3-1.0-1.80.9-2.4-0.7-0.30.3-0.3-0.3-0.3-0.3-2.92.9-1.4-1.5-1.1-1.6-1.80.7-2.0
Body weight1.45.915.7-4.03.23.7-3.2-3.53.4-3.2-3.53.1-3.2-2.61.4-1.41.41.51.51.5-2.72.7-0.2-0.20.0-0.4-0.71.3-1.0
Weight adjusted by age1.11.63.1-1.51.71.4-1.7-1.71.7-1.7-1.71.7-0.9-1.81.2-1.21.21.41.41.3-0.10.10.90.80.70.80.70.00.6
Bone surface2.64.713.4-3.43.23.1-3.1-2.62.4-2.5-2.72.4-3.7-1.5-0.40.4-0.4-0.2-0.2-0.1-2.82.8-1.5-1.5-1.7-1.5-1.8-0.1-2.0
Bone volume1.52.76.7-2.12.01.8-1.9-1.41.2-1.3-1.51.2-2.6-0.6-1.11.1-1.1-0.9-0.9-0.8-2.42.4-1.8-1.7-1.7-1.8-1.9-1.0-2.1
Breakpoint value in progressive ratio session1.92.35.9-2.22.42.2-2.4-2.22.1-2.2-2.22.2-1.7-1.90.8-0.80.90.91.11.1-0.90.90.30.30.00.20.0-0.1-0.1
Number of licking bursts0.20.30.9-0.80.90.8-0.9-0.70.7-0.8-0.50.8-0.8-0.3-0.10.1-0.00.10.40.3-0.30.3-0.1-0.1-0.2-0.1-0.10.7-0.2
Context. condit. distance diff. score1.11.33.21.6-1.7-1.81.71.7-1.61.71.6-1.71.11.2-0.80.8-0.9-0.8-1.1-1.10.4-0.4-0.4-0.4-0.1-0.4-0.3-0.9-0.2
Locomotion velocity, session 10.30.31.10.2-0.3-0.00.3-0.00.1-0.00.30.00.60.00.5-0.50.50.60.70.90.5-0.50.80.80.70.70.71.10.7
Locomotion distance, session 10.70.83.2-1.00.40.8-0.4-0.50.4-0.3-0.30.2-1.20.4-0.70.7-0.7-0.7-0.5-0.3-1.81.8-1.1-1.1-0.8-1.2-1.31.1-1.3
Locomotion velocity, session 21.31.53.9-1.91.62.0-1.6-1.81.7-1.6-1.61.6-1.5-1.30.9-0.90.90.90.81.0-1.31.30.20.20.20.1-0.10.9-0.2
Locomotion distance, session 20.50.62.5-1.30.51.0-0.6-0.90.8-0.6-0.70.5-0.9-0.2-0.10.1-0.0-0.10.10.2-1.61.6-0.6-0.6-0.1-0.7-0.81.5-0.9
Locomotion velocity, session 30.40.40.70.1-0.4-0.30.40.4-0.40.50.4-0.5-0.30.8-0.90.9-0.8-0.7-0.7-0.7-0.80.8-0.8-0.8-0.5-0.8-0.8-0.6-0.8
Locomotion distance, session 30.00.00.20.0-0.1-0.10.10.0-0.00.10.1-0.1-0.00.3-0.10.1-0.10.0-0.10.0-0.20.2-0.1-0.10.2-0.1-0.1-0.5-0.1
Stereotopy head waving bouts, day 30.91.12.10.8-1.4-1.11.41.1-1.21.31.1-1.40.31.4-0.90.9-0.9-0.9-1.1-1.1-0.80.8-1.0-1.0-0.4-1.0-0.9-0.6-0.9
Stereotopy head waving duration, day 31.21.42.31.0-1.4-1.31.41.3-1.41.41.2-1.50.31.5-1.31.3-1.2-1.2-1.3-1.4-0.50.5-1.1-1.1-0.9-1.1-1.0-0.8-1.0
Locomotion velocity, session 70.60.71.30.1-0.6-0.50.60.5-0.60.70.3-0.7-0.70.6-0.90.9-0.8-0.8-1.1-1.0-0.90.9-1.1-1.1-0.9-1.1-1.1-0.7-1.1
Locomotion distance, session 70.10.10.4-0.2-0.4-0.10.4-0.0-0.00.2-0.2-0.3-0.3-0.20.0-0.00.10.2-0.2-0.0-0.70.7-0.2-0.3-0.1-0.4-0.4-0.1-0.4
Stereotopy head waving bouts, day 70.91.16.4-0.10.3-0.1-0.20.2-0.30.2-0.0-0.2-1.00.7-1.11.1-1.2-1.1-1.3-1.3-1.01.0-1.2-1.2-1.3-1.2-1.2-2.5-1.2
Stereotopy head waving duration, day 71.11.34.3-1.21.30.9-1.2-0.70.6-0.7-1.00.7-1.9-0.0-0.60.6-0.7-0.6-0.9-0.8-1.61.6-1.2-1.2-1.3-1.2-1.3-2.1-1.3
Locomotion velocity, session 80.70.91.7-1.00.81.1-0.9-1.21.2-1.1-1.11.1-0.3-1.11.1-1.11.10.91.11.2-0.20.20.70.71.00.70.61.30.5
Locomotion distance, session 80.30.40.60.5-0.7-0.60.70.7-0.70.80.8-0.80.30.7-0.70.7-0.8-0.7-0.8-0.7-0.30.3-0.6-0.6-0.1-0.6-0.50.1-0.5
Degree of sensitization distance0.20.20.7-0.3-0.20.00.2-0.0-0.00.2-0.2-0.2-0.6-0.0-0.30.3-0.2-0.3-0.4-0.3-0.80.8-0.6-0.6-0.6-0.7-0.70.2-0.7
Degree of sensitization stereotypy0.80.86.4-0.91.30.8-1.2-0.70.6-0.8-1.00.8-1.4-0.3-0.30.3-0.4-0.3-0.6-0.5-0.80.8-0.6-0.6-1.0-0.6-0.7-2.5-0.7
Conditioned locomotion1.61.83.3-1.31.11.4-1.2-1.61.6-1.5-1.61.5-0.5-1.81.8-1.81.71.61.71.60.1-0.11.21.11.21.10.91.10.8
Cocaine response after cond. corrected0.50.71.81.3-1.3-1.31.31.2-1.21.21.1-1.21.00.7-0.30.3-0.3-0.3-0.4-0.50.5-0.50.0-0.00.10.00.1-0.60.2
Cocaine response after cond. not corrected0.40.51.31.0-1.0-1.11.01.0-1.01.01.1-1.00.70.9-0.60.6-0.6-0.6-0.5-0.60.3-0.3-0.2-0.2-0.2-0.2-0.1-0.3-0.0
Cocaine response before conditioning0.40.51.8-1.01.31.0-1.3-0.90.9-1.0-0.61.0-1.0-0.2-0.30.3-0.3-0.10.00.1-0.40.4-0.3-0.2-0.5-0.2-0.30.6-0.4
Saline control response1.92.56.5-2.52.22.6-2.2-2.32.3-2.2-2.02.1-1.7-1.70.8-0.80.81.01.31.3-1.51.50.20.30.20.1-0.11.4-0.2
Bone: connectivity density2.03.18.9-2.61.92.1-1.9-1.71.5-1.4-1.81.4-2.9-0.9-0.60.6-0.7-0.7-0.7-0.6-3.03.0-1.7-1.7-1.7-1.8-2.0-0.0-2.2
Bone: cortical apparent density0.40.50.9-0.20.30.4-0.3-0.50.5-0.5-0.60.50.2-0.70.9-0.90.90.90.80.90.6-0.60.90.90.80.90.80.60.8
Bone: cortical area0.61.02.0-1.01.41.3-1.4-1.21.3-1.4-1.11.4-0.3-1.40.8-0.80.80.91.00.90.4-0.40.70.80.60.80.70.30.6
Bone: cortical porosity0.30.31.1-0.50.20.3-0.1-0.20.1-0.0-0.20.0-0.60.1-0.50.5-0.5-0.3-0.3-0.4-1.11.1-0.8-0.8-0.5-0.8-0.9-0.6-0.9
Bone: cortical porosity0.20.31.0-0.80.40.6-0.4-0.50.5-0.4-0.50.3-0.7-0.3-0.10.1-0.10.10.0-0.1-1.01.0-0.5-0.5-0.2-0.6-0.6-0.3-0.7
Bone: cortical thickness4.06.710.2-2.12.52.6-2.5-2.82.9-2.9-2.62.9-0.2-3.23.1-3.13.13.13.13.00.9-0.92.62.62.42.52.31.62.2
Bone: cortical thickness1.82.14.1-0.70.51.0-0.6-1.21.3-1.1-1.11.10.3-1.32.0-2.02.01.92.01.90.4-0.41.71.61.81.61.51.81.4
Bone: cortical tissue density0.50.71.2-0.40.40.5-0.5-0.70.7-0.7-0.70.70.1-0.81.1-1.11.11.11.01.00.6-0.61.01.00.91.00.90.70.9
Condit. Reinf. active minus inactive responses0.20.30.9-0.80.70.5-0.7-0.60.5-0.5-0.40.5-0.9-0.1-0.30.3-0.4-0.20.20.0-0.80.8-0.5-0.5-0.4-0.5-0.5-0.1-0.6
Condit. Reinf. active-inactive response ratio0.10.10.5-0.40.50.2-0.5-0.30.2-0.3-0.10.3-0.70.1-0.50.5-0.4-0.30.1-0.1-0.30.3-0.4-0.4-0.6-0.4-0.40.1-0.4
Condit. Reinf. active responses0.10.10.4-0.60.60.4-0.6-0.40.4-0.4-0.30.4-0.6-0.2-0.30.3-0.3-0.10.10.1-0.50.5-0.3-0.3-0.2-0.3-0.40.1-0.4
Condit. Reinf. inactive responses0.00.00.10.0-0.1-0.10.10.1-0.10.1-0.0-0.10.00.0-0.30.3-0.2-0.2-0.3-0.2-0.20.2-0.2-0.20.0-0.2-0.2-0.2-0.2
Incentive salience index mean0.30.41.1-0.90.80.7-0.8-0.70.6-0.6-0.60.6-1.0-0.4-0.20.2-0.3-0.10.10.0-1.01.0-0.5-0.5-0.4-0.5-0.6-0.0-0.7
Condit. Reinf. lever presses0.20.31.0-0.91.00.8-1.0-0.80.8-0.9-0.80.9-0.7-0.90.2-0.20.10.30.30.3-0.30.3-0.00.0-0.00.0-0.1-0.2-0.1
Condit. Reinf. active minus inactive responses0.81.02.40.10.3-0.1-0.20.4-0.50.30.5-0.3-0.61.1-1.51.5-1.5-1.5-1.3-1.3-0.60.6-1.3-1.2-1.4-1.2-1.2-1.1-1.1
Condit. Reinf. active-inactive response ratio1.11.33.10.8-0.2-0.70.31.0-1.10.81.1-0.8-0.01.4-1.81.8-1.7-1.7-1.5-1.4-0.10.1-1.2-1.1-1.3-1.0-0.9-1.3-0.9
Condit. Reinf. active responses1.11.52.9-0.70.70.5-0.6-0.1-0.0-0.0-0.10.0-1.40.9-1.51.5-1.5-1.4-1.3-1.3-1.61.6-1.7-1.6-1.6-1.6-1.7-1.1-1.7
Condit. Reinf. inactive responses0.70.93.5-1.20.50.8-0.5-0.70.5-0.4-0.80.3-1.50.0-0.30.3-0.4-0.3-0.5-0.6-1.91.9-1.1-1.1-0.8-1.2-1.3-0.3-1.4
Condit. Reinf. lever presses1.21.64.8-2.02.22.0-2.1-1.71.6-1.7-1.61.7-1.9-0.8-0.10.1-0.20.10.10.1-1.31.3-0.7-0.6-0.7-0.6-0.7-0.9-0.9
Condit. Reinf. lever reinforcers received0.91.32.4-0.91.00.8-0.9-0.40.3-0.4-0.40.3-1.50.6-1.21.2-1.3-1.2-1.0-1.1-1.61.6-1.5-1.4-1.4-1.4-1.5-1.0-1.5
Conditioned reinforcement - actives0.10.10.50.10.40.1-0.4-0.10.1-0.20.00.30.3-0.2-0.00.00.1-0.1-0.10.10.7-0.70.30.40.20.40.4-0.00.5
Conditioned reinforcement - inactives1.42.03.61.9-1.3-1.91.41.9-1.91.71.7-1.60.81.7-1.51.5-1.7-1.6-1.7-1.61.1-1.1-0.8-0.7-0.8-0.6-0.4-1.5-0.3
Conditioned locomotion4.25.412.43.5-3.0-3.33.03.4-3.33.13.4-3.12.82.6-1.91.9-2.0-2.1-1.9-1.92.1-2.1-0.6-0.4-0.4-0.3-0.0-1.00.2
Patch foraging indifference point 0 sec0.20.41.30.2-0.1-0.30.20.4-0.40.40.5-0.4-0.00.7-1.01.0-1.0-1.1-0.5-0.7-0.40.4-0.7-0.7-0.9-0.7-0.70.8-0.6
Patch foraging indifference point AUC1.62.34.4-1.82.02.0-2.0-2.02.0-2.0-2.12.0-1.3-1.81.7-1.71.71.61.21.3-0.10.10.90.90.80.90.7-0.50.6
Delay disc. indifference point, 0s delay1.11.22.30.7-1.5-1.01.51.1-1.11.41.2-1.40.31.3-1.01.0-1.1-1.1-0.9-0.9-1.11.1-1.1-1.1-0.5-1.2-1.10.2-1.1
Delay disc. indifference point, 16s delay1.11.23.00.7-0.7-0.90.71.0-1.11.00.9-1.0-0.11.3-1.71.7-1.6-1.6-1.3-1.3-0.40.4-1.2-1.2-1.3-1.1-1.1-0.4-1.0
Delay disc. indifference point, 2s delay0.40.41.00.3-0.4-0.30.50.6-0.60.60.7-0.60.00.8-1.01.0-0.9-0.8-0.6-0.6-0.40.4-0.8-0.7-0.6-0.7-0.7-0.2-0.7
Delay disc. indifference point, 24s delay0.20.22.30.3-0.6-0.40.60.2-0.10.30.2-0.30.5-0.10.2-0.20.40.20.50.40.2-0.20.50.40.50.40.41.50.4
Delay disc. indifference point, 4s delay0.50.61.50.2-1.0-0.40.90.5-0.60.80.5-0.80.00.7-0.90.9-0.6-0.7-0.6-0.4-1.01.0-0.7-0.8-0.4-0.8-0.81.2-0.8
Delay disc. indifference point, 8s delay0.40.42.30.1-0.7-0.40.70.4-0.40.60.3-0.6-0.00.5-0.80.8-0.6-0.8-0.5-0.4-0.90.9-0.6-0.7-0.3-0.7-0.71.5-0.7
Indifference point function ln k3.86.615.83.7-3.9-3.73.93.6-3.63.64.0-3.63.43.1-2.02.0-2.0-1.9-1.4-1.61.6-1.6-0.5-0.4-0.1-0.4-0.10.60.2
Indifference point function log k3.86.615.83.7-3.9-3.73.93.6-3.63.64.0-3.63.43.1-2.02.0-2.0-1.9-1.4-1.61.6-1.6-0.5-0.4-0.1-0.4-0.10.60.2
Patch foraging total patch changes 0 sec0.10.11.50.2-0.2-0.20.20.2-0.20.20.4-0.20.40.4-0.40.4-0.3-0.50.2-0.1-0.00.0-0.10.0-0.2-0.00.01.20.0
Patch foraging total patch changes 12 sec2.53.27.5-2.72.52.7-2.5-2.52.5-2.4-2.72.4-2.1-2.01.5-1.51.41.31.01.0-1.61.60.30.30.10.2-0.1-0.1-0.3
Patch foraging total patch changes 18 sec0.30.51.6-1.11.01.1-1.0-0.90.8-0.8-1.10.8-1.3-0.40.2-0.20.30.10.00.0-1.01.0-0.3-0.3-0.5-0.4-0.5-0.2-0.5
Patch foraging total patch changes 24 sec1.01.83.1-1.51.61.7-1.7-1.71.7-1.7-1.51.8-0.8-1.41.5-1.51.51.31.41.5-0.30.30.90.90.80.90.71.10.6
Patch foraging total patch changes 6 sec0.71.12.7-1.61.51.6-1.5-1.41.4-1.3-1.51.3-1.6-0.80.5-0.50.40.40.50.4-1.31.3-0.2-0.2-0.3-0.3-0.4-0.2-0.5
Patch foraging time to switch 0 sec1.22.67.7-2.31.81.6-1.7-1.61.4-1.3-1.91.3-2.8-0.9-0.50.5-0.6-0.5-0.6-0.5-2.62.6-1.5-1.6-1.7-1.6-1.8-0.1-2.0
Patch foraging water rate 0 sec2.04.212.63.3-2.5-2.72.52.5-2.32.22.9-2.13.61.5-0.30.3-0.2-0.20.1-0.03.1-3.11.31.41.41.51.70.51.9
Patch foraging water rate 12 sec3.77.622.34.4-4.3-3.84.23.7-3.53.64.1-3.54.72.5-0.70.7-0.6-0.7-0.4-0.53.0-3.01.01.11.51.21.50.81.8
Patch foraging water rate 18 sec1.52.36.42.4-2.4-2.02.32.0-1.92.02.3-2.02.51.6-0.70.7-0.6-0.6-0.1-0.31.6-1.60.40.50.60.50.70.50.8
Patch foraging water rate 24 sec2.73.810.63.1-2.8-2.82.82.5-2.32.32.7-2.23.21.4-0.30.3-0.1-0.00.00.02.6-2.61.11.11.11.21.40.11.6
Patch foraging water rate 6 sec2.73.913.93.0-2.8-2.52.72.3-2.22.22.8-2.13.71.50.0-0.00.00.00.40.32.4-2.41.21.31.61.41.61.01.8
Seeking ratio, delayed vs. immediate footshock0.70.92.0-0.1-0.3-0.40.30.3-0.40.50.3-0.5-0.40.7-1.41.4-1.3-1.3-0.8-0.9-1.01.0-1.2-1.2-1.0-1.2-1.21.1-1.2
Distance traveled before self-admin0.40.51.5-0.80.90.9-0.9-0.60.5-0.6-0.50.6-1.20.0-0.40.4-0.5-0.5-0.4-0.3-0.90.9-0.7-0.6-0.8-0.7-0.7-0.4-0.8
Distance traveled after self-admin0.10.20.9-0.50.70.5-0.7-0.40.4-0.5-0.50.5-0.8-0.0-0.00.0-0.20.0-0.1-0.1-0.30.3-0.2-0.1-0.3-0.1-0.2-0.9-0.2
Extensor digitorum longus weight4.718.435.9-5.75.65.9-5.6-6.05.9-5.8-6.05.7-3.6-5.54.1-4.14.14.34.24.1-1.61.62.22.12.11.91.41.81.0
Bone: elastic displacement1.41.73.71.2-1.0-0.90.90.5-0.40.40.7-0.41.8-0.21.3-1.31.21.11.21.21.9-1.91.71.71.71.71.81.21.8
Bone: elastic work2.02.64.7-0.90.91.2-1.0-1.51.5-1.4-1.21.50.2-1.62.2-2.22.12.02.12.10.8-0.81.81.81.91.81.72.11.6
Bone: endosteal estimation1.63.66.71.1-1.4-1.41.51.8-1.91.91.8-1.9-0.02.1-2.62.6-2.6-2.4-2.2-2.2-1.01.0-2.2-2.1-2.0-2.1-2.0-0.9-1.9
Bone: endosteal perimeter2.75.711.91.1-1.1-1.51.22.0-2.12.02.1-2.0-0.32.8-3.43.4-3.4-3.3-2.9-3.0-1.01.0-2.9-2.8-2.8-2.7-2.6-1.6-2.5
Epididymis fat weight2.27.615.13.9-3.2-3.73.33.9-3.83.63.8-3.52.53.2-2.82.8-2.8-2.6-2.6-2.72.0-2.0-1.2-1.1-1.2-0.9-0.6-2.4-0.3
Delta time in closed arm before/after self-admin0.60.61.6-0.5-0.10.40.1-0.60.6-0.4-0.80.30.0-1.01.3-1.31.21.21.00.9-0.40.40.80.71.10.60.61.00.5
Delta time in open arm before/after self-admin0.30.34.3-0.40.90.3-0.9-0.40.4-0.6-0.50.6-0.7-0.30.1-0.10.00.2-0.10.00.3-0.3-0.00.0-0.40.10.0-2.10.0
Diff in mean of infusions in LGA sessions0.60.72.0-1.01.11.2-1.1-1.11.1-1.1-1.21.2-0.6-1.40.7-0.71.00.80.80.7-0.10.10.60.60.40.60.50.70.4
Delay discount exponential model param0.50.61.60.10.50.2-0.5-0.30.3-0.5-0.30.50.3-0.71.2-1.20.81.00.50.51.0-1.00.90.90.60.90.9-1.30.9
Extinction: sum of active levers before priming1.51.64.1-2.02.02.0-1.9-1.71.6-1.7-1.91.6-1.7-1.50.2-0.20.30.10.30.3-1.41.4-0.5-0.4-0.7-0.5-0.7-0.0-0.8
Active lever presses in extinction session 62.22.25.3-1.82.31.9-2.3-2.02.0-2.1-2.02.1-1.7-1.61.4-1.41.11.21.31.1-0.20.20.60.60.30.60.5-1.20.3
Bone: final force1.11.74.7-2.02.02.2-2.0-1.91.9-1.9-1.71.9-1.2-1.50.9-0.90.91.11.01.1-0.70.70.30.40.50.30.10.6-0.0
Bone: final moment1.01.64.3-1.91.92.1-1.9-1.91.8-1.8-1.61.8-1.2-1.50.8-0.80.81.01.01.0-0.70.70.30.30.50.30.10.7-0.0
Food consumed during 24 hour testing period0.20.20.90.10.50.2-0.5-0.20.2-0.4-0.00.40.3-0.30.2-0.20.20.60.40.31.0-1.00.60.60.50.70.7-0.70.7
Glucose3.25.07.71.6-2.1-2.22.22.3-2.42.52.1-2.50.12.7-2.72.7-2.7-2.8-2.6-2.7-1.21.2-2.4-2.4-2.0-2.3-2.2-1.3-2.1
Heart weight2.23.45.40.8-1.8-1.41.91.6-1.71.91.2-2.0-0.41.8-2.12.1-2.1-1.9-2.3-2.1-1.81.8-2.2-2.2-2.0-2.3-2.2-0.7-2.2
Delay discount hyperbolic model param0.60.61.40.00.50.2-0.5-0.30.4-0.5-0.40.60.3-0.71.2-1.20.91.00.60.61.0-1.00.90.90.61.01.0-1.11.0
Intermittent access intake day 1-15 change0.40.82.21.5-0.9-1.40.91.2-1.21.01.3-1.01.10.9-0.40.4-0.6-0.6-0.6-0.61.3-1.30.10.2-0.10.30.4-1.10.5
Intermittent access intake escalation0.30.72.01.3-0.7-1.20.71.0-1.00.81.1-0.71.10.7-0.30.3-0.4-0.4-0.4-0.41.4-1.40.30.3-0.10.40.5-1.00.6
Intermittent access intake escalation 20.70.82.31.4-0.7-1.20.71.1-1.10.91.1-0.81.10.7-0.40.4-0.4-0.4-0.4-0.41.5-1.50.30.4-0.00.50.6-1.20.7
Intermitt. access day 1 inactive lever presses0.00.10.90.3-0.0-0.40.00.3-0.30.20.1-0.2-0.00.2-0.00.0-0.3-0.2-0.2-0.30.5-0.5-0.1-0.1-0.3-0.00.0-1.00.0
Intermitt. access day 15 inactive lever presses0.71.44.21.1-0.7-1.20.81.3-1.31.20.9-1.10.01.5-1.41.4-1.5-1.6-1.5-1.60.4-0.4-1.1-1.1-1.3-1.0-0.9-2.1-0.8
Intermitt. access escalation Index2.13.06.32.1-2.5-2.12.52.4-2.42.52.3-2.51.81.8-1.61.6-1.6-1.7-1.7-1.80.2-0.2-1.1-1.0-0.6-1.0-0.8-0.4-0.7
Intermittent access day 1 total infusions3.55.610.71.1-1.6-1.71.72.0-2.22.21.6-2.3-0.62.3-3.23.2-3.1-3.1-3.3-2.8-1.41.4-2.8-2.8-2.5-2.8-2.7-1.5-2.6
Intermittent access day 15 total infusions3.04.47.12.3-2.0-2.42.02.6-2.62.52.4-2.40.92.4-2.62.6-2.6-2.6-2.7-2.40.6-0.6-1.6-1.6-1.7-1.5-1.3-2.1-1.1
Intermittent access terminal intake (last 3 days)3.54.68.21.9-1.7-2.21.82.4-2.42.32.1-2.30.32.4-2.82.8-2.7-2.7-2.9-2.60.1-0.1-2.0-1.9-2.1-1.8-1.6-2.7-1.5
Intermittent access total infusions3.64.38.01.4-1.5-1.71.62.0-2.12.01.7-2.1-0.12.1-2.82.8-2.7-2.7-2.8-2.6-0.60.6-2.3-2.2-2.1-2.2-2.0-2.0-1.9
Intermittent access day 1 locomotion2.73.56.41.0-1.3-1.41.41.7-1.81.81.2-1.8-0.52.0-2.52.5-2.4-2.4-2.5-2.3-0.90.9-2.2-2.2-2.0-2.2-2.1-1.4-2.0
Intermittent access day 15 total locomotion2.34.27.72.0-1.6-2.11.72.4-2.42.22.1-2.20.62.3-2.62.6-2.7-2.6-2.8-2.50.3-0.3-1.9-1.8-1.9-1.7-1.5-2.2-1.4
Intermittent access total locomotion6.37.613.42.3-2.2-2.62.33.0-3.12.92.6-2.90.43.1-3.63.6-3.7-3.6-3.7-3.5-0.20.2-2.8-2.7-2.7-2.5-2.4-2.6-2.2
Intermittent access standard deviation0.40.81.91.4-1.1-1.31.11.2-1.21.11.2-1.10.91.0-0.50.5-0.6-0.5-0.5-0.51.1-1.10.00.0-0.10.10.2-1.30.3
Left kidney weight0.52.34.92.2-2.2-2.12.22.2-2.22.22.2-2.11.91.5-1.31.3-1.3-1.1-1.5-1.30.7-0.7-0.5-0.5-0.1-0.4-0.3-0.6-0.1
Right kidney weight0.31.34.21.8-1.5-1.51.51.5-1.51.41.6-1.32.10.7-0.50.5-0.5-0.3-0.4-0.31.4-1.40.40.50.60.50.60.50.7
Cocaine induced anxiety0.10.10.7-0.20.50.1-0.4-0.20.2-0.3-0.50.3-0.5-0.0-0.10.1-0.1-0.0-0.1-0.10.2-0.2-0.1-0.1-0.1-0.1-0.1-0.9-0.1
Post-drug Anxiety0.40.41.3-0.81.10.9-1.1-0.90.9-1.0-0.91.0-0.7-0.60.4-0.40.40.50.40.5-0.00.00.20.30.30.30.2-0.20.1
Baseline Anxiety0.30.41.5-0.40.30.6-0.4-0.60.6-0.5-0.20.50.2-0.60.7-0.70.80.70.70.8-0.00.00.60.70.90.60.61.20.5
Tail length0.83.05.5-0.90.81.2-0.9-1.51.6-1.4-1.31.40.6-2.02.3-2.32.32.32.32.20.8-0.82.02.02.21.91.81.91.7
Length with tail1.67.111.1-2.52.63.0-2.7-3.13.2-3.1-2.83.1-0.7-3.33.2-3.23.33.33.33.10.3-0.32.42.32.42.22.02.01.8
Length without tail1.65.38.1-2.32.42.7-2.4-2.82.9-2.8-2.42.8-0.8-2.62.7-2.72.72.82.82.70.0-0.02.02.02.01.91.71.51.5
Times rat made contact with spout0.30.41.1-0.90.50.8-0.5-0.70.7-0.6-0.70.5-1.0-0.50.2-0.20.20.20.40.3-1.01.0-0.3-0.3-0.3-0.4-0.50.9-0.5
Lifetime Intake2.63.26.31.1-1.3-1.41.41.7-1.81.81.4-1.8-0.21.7-2.42.4-2.3-2.3-2.5-2.2-0.80.8-2.0-2.0-1.8-1.9-1.9-1.8-1.8
Liver weight, left0.61.03.01.5-1.7-1.31.71.2-1.11.21.2-1.21.70.40.3-0.30.30.30.10.21.0-1.00.70.70.90.70.80.70.9
Liver weight, right1.11.96.32.1-2.5-2.12.51.9-1.92.12.0-2.12.01.3-0.80.8-0.6-0.6-0.5-0.50.7-0.70.00.00.40.00.20.40.3
Locomotor activity1.11.75.31.9-2.0-1.61.91.5-1.41.51.9-1.52.31.10.1-0.10.00.00.50.51.4-1.40.90.91.10.91.11.41.2
Locomotor testing distance1.32.47.02.2-2.5-1.82.41.8-1.71.82.3-1.82.61.3-0.00.0-0.1-0.00.40.51.5-1.50.90.91.30.91.11.71.2
Locomotor testing rearing0.91.95.91.9-2.4-1.82.42.0-1.92.12.0-2.11.61.8-0.80.8-0.9-0.9-0.8-0.80.4-0.4-0.3-0.40.1-0.4-0.20.2-0.1
Locomotion in novel chamber3.44.38.32.8-2.6-2.82.62.9-2.82.82.9-2.72.02.5-2.22.2-2.1-2.2-1.9-1.91.1-1.1-0.9-0.8-0.8-0.7-0.5-0.7-0.3
Locomotion in novel chamber post-restriction1.52.45.22.1-1.9-2.11.92.2-2.12.02.3-2.01.31.9-1.41.4-1.5-1.6-1.6-1.50.7-0.7-0.8-0.7-0.8-0.6-0.4-1.6-0.3
Fecal boli incidents, locomotor time 10.20.36.3-0.00.60.2-0.5-0.10.1-0.3-0.40.3-0.6-0.10.3-0.30.00.3-0.3-0.30.6-0.60.10.0-0.40.10.1-2.50.1
Change in fecal boli incidents, locomotor task0.40.45.5-0.0-0.5-0.20.50.2-0.20.40.3-0.40.10.3-0.50.5-0.3-0.70.1-0.2-0.90.9-0.4-0.4-0.2-0.5-0.52.4-0.5
Time >=10cm from walls, locomotor time 12.62.76.40.5-0.4-0.90.51.1-1.21.10.8-1.1-0.81.6-2.52.5-2.3-2.4-2.5-2.2-0.70.7-2.1-2.1-2.1-2.0-1.9-1.0-1.9
Bouts of movement, locomotor time 10.81.02.5-1.31.61.1-1.6-1.41.4-1.5-1.41.5-1.2-1.10.9-0.90.80.80.60.8-0.00.00.50.40.00.40.30.20.3
Total resting periods, locomotor time 10.50.62.0-1.01.40.9-1.4-1.11.0-1.2-1.11.2-1.2-0.70.5-0.50.30.40.30.4-0.10.10.10.1-0.30.10.0-0.00.0
Rest time, locomotor task time 10.91.12.71.6-1.2-1.31.21.5-1.41.31.6-1.21.41.3-0.90.9-0.9-1.0-0.6-0.71.3-1.3-0.10.0-0.00.10.20.30.4
Distance moved, locomotor task time 10.50.72.3-0.80.40.4-0.4-0.40.3-0.2-0.60.1-1.10.1-0.60.6-0.6-0.7-0.7-0.5-1.51.5-1.0-1.1-0.9-1.1-1.1-0.8-1.2
Vertical activity count, locomotor time 10.20.41.10.8-1.0-1.01.00.9-0.90.90.7-0.90.60.5-0.60.6-0.4-0.5-0.5-0.60.1-0.1-0.2-0.2-0.1-0.2-0.2-0.2-0.1
Time >=10cm from walls, locomotor time 20.10.10.40.00.3-0.1-0.30.0-0.0-0.10.10.1-0.20.2-0.60.6-0.5-0.6-0.3-0.30.1-0.1-0.3-0.2-0.4-0.2-0.20.4-0.2
Bouts of movement, locomotor time 20.20.41.3-0.90.80.6-0.8-0.80.8-0.8-1.00.7-1.1-0.70.4-0.40.40.50.30.3-0.50.5-0.1-0.1-0.3-0.1-0.2-0.5-0.3
Total resting periods, locomotor time 20.10.21.1-0.70.60.3-0.5-0.50.5-0.4-0.70.4-1.0-0.30.1-0.10.10.2-0.1-0.1-0.50.5-0.3-0.4-0.5-0.4-0.4-1.0-0.5
Rest time, locomotor task time 21.31.73.51.8-1.9-1.81.91.8-1.81.81.7-1.81.31.5-1.01.0-0.9-1.0-1.4-1.10.8-0.8-0.4-0.4-0.2-0.4-0.2-0.6-0.1
Distance moved, locomotor task time 20.81.02.1-1.31.51.3-1.5-1.41.4-1.4-1.21.4-0.7-1.20.7-0.70.70.51.01.0-0.40.40.50.50.40.50.41.30.3
Vertical activity count, locomotor time 21.01.33.10.20.0-0.0-0.1-0.40.5-0.5-0.20.51.1-1.01.2-1.21.41.21.61.41.1-1.11.61.61.71.61.61.81.6
Light reinforcement 10.10.21.80.5-0.6-0.20.60.5-0.40.50.6-0.50.70.4-0.30.3-0.2-0.3-0.10.00.1-0.10.00.10.30.00.11.30.1
Light reinforcement 20.50.71.71.2-0.6-0.90.61.1-1.10.91.3-0.80.81.1-1.01.0-0.9-0.9-0.5-0.81.0-1.0-0.3-0.2-0.5-0.2-0.1-0.80.0
Bone: marrow area1.73.87.01.2-1.5-1.51.61.8-2.02.01.8-2.0-0.02.2-2.62.6-2.6-2.4-2.3-2.3-1.01.0-2.3-2.2-2.0-2.2-2.1-0.9-2.0
Bone: maximum diameter0.10.10.8-0.20.90.4-0.8-0.30.3-0.5-0.00.5-0.1-0.2-0.40.4-0.4-0.3-0.0-0.20.5-0.5-0.2-0.0-0.40.0-0.0-0.1-0.0
Bone: maximum force1.52.77.5-2.72.72.7-2.7-2.32.1-2.2-2.12.2-2.7-1.20.0-0.0-0.00.10.40.4-1.61.6-0.8-0.7-0.9-0.8-1.00.1-1.1
Bone: maximum moment1.42.56.7-2.62.62.5-2.5-2.12.0-2.1-2.02.1-2.5-1.10.0-0.0-0.00.10.40.4-1.61.6-0.7-0.7-0.8-0.7-0.90.3-1.1
Mean time between licks in bursts0.20.42.8-0.50.10.6-0.2-0.60.6-0.4-0.40.40.1-0.50.6-0.60.60.81.00.9-0.20.20.50.50.80.50.41.70.4
Mean num. licks in bursts0.10.20.80.5-0.9-0.60.90.6-0.60.70.4-0.70.20.3-0.10.1-0.1-0.2-0.5-0.4-0.30.3-0.3-0.3-0.2-0.3-0.3-0.4-0.3
Cd content in liver0.91.02.01.2-1.0-1.11.01.3-1.31.21.4-1.20.51.4-1.21.2-1.2-1.2-1.1-1.00.2-0.2-0.7-0.7-0.9-0.6-0.5-0.7-0.4
Co content in liver1.82.16.21.7-1.7-1.41.61.1-0.91.01.3-1.02.50.31.1-1.11.10.90.91.01.8-1.81.61.62.01.61.81.21.9
Cu content in liver0.20.20.6-0.20.00.10.00.0-0.10.10.1-0.1-0.30.5-0.40.4-0.4-0.4-0.4-0.5-0.80.8-0.6-0.5-0.4-0.6-0.6-0.6-0.6
Fe content in liver0.30.40.7-0.30.30.5-0.4-0.50.6-0.5-0.40.50.1-0.50.8-0.80.80.80.90.80.3-0.30.70.70.70.70.70.10.7
K content in liver0.30.30.9-0.90.60.7-0.6-0.70.6-0.5-0.80.5-0.9-0.3-0.00.00.00.00.10.1-1.01.0-0.4-0.4-0.3-0.4-0.50.1-0.6
Mg content in liver0.50.51.10.4-0.7-0.60.70.6-0.70.80.6-0.8-0.11.1-0.90.9-0.9-0.8-0.6-0.8-0.50.5-0.8-0.8-0.6-0.8-0.8-0.5-0.7
Mn content in liver2.32.57.0-2.22.72.2-2.6-2.22.2-2.3-2.52.3-2.1-1.71.0-1.01.01.11.00.9-0.40.40.30.3-0.10.30.1-1.2-0.0
Na content in liver0.80.81.5-0.20.80.7-0.8-0.60.7-0.9-0.20.90.5-0.60.8-0.80.80.71.21.11.1-1.11.11.20.91.21.11.21.1
Rb content in liver1.51.73.21.3-1.8-1.51.81.6-1.61.81.4-1.80.51.7-1.31.3-1.3-1.4-1.3-1.4-0.50.5-1.1-1.1-0.9-1.1-1.0-0.7-0.9
Se content in liver0.30.42.80.20.1-0.2-0.00.3-0.40.20.3-0.2-0.30.5-0.80.8-0.8-0.7-0.8-0.8-0.10.1-0.7-0.6-0.8-0.6-0.6-1.7-0.5
Sr content in liver2.32.03.4-1.31.71.6-1.7-1.71.7-1.8-1.71.8-0.6-1.91.6-1.61.61.61.61.60.5-0.51.31.21.01.21.10.81.0
Zn content in liver0.10.20.3-0.60.30.5-0.3-0.50.5-0.4-0.50.4-0.2-0.60.5-0.50.50.50.40.3-0.50.50.10.10.10.10.00.2-0.0
Bone: minimum diameter2.34.17.80.6-0.9-1.11.01.4-1.61.61.2-1.6-0.92.2-2.72.7-2.8-2.7-2.4-2.5-1.61.6-2.6-2.6-2.6-2.6-2.5-1.2-2.5
Time in familiar zone, hab. session 10.50.51.20.3-0.2-0.30.20.5-0.60.50.5-0.5-0.40.9-1.11.1-1.1-1.0-0.8-0.8-0.40.4-0.9-0.9-0.9-0.8-0.8-0.5-0.8
Time in novel zone, hab. session 10.40.41.10.6-0.8-0.60.70.4-0.30.40.4-0.41.0-0.20.7-0.70.60.60.60.50.7-0.70.80.70.90.70.80.60.8
Total zone transitions, hab. session 10.40.61.4-1.21.11.1-1.1-1.11.0-1.0-1.01.0-0.9-0.80.2-0.20.20.30.40.5-0.80.8-0.1-0.1-0.1-0.1-0.20.4-0.3
Total locomotion distance, hab. session 10.30.40.80.6-0.6-0.80.70.7-0.80.80.8-0.80.20.8-0.80.8-0.8-0.9-0.7-0.6-0.10.1-0.6-0.5-0.5-0.5-0.50.4-0.4
Locomotion velocity, hab. session 10.10.10.30.1-0.2-0.20.20.2-0.20.20.2-0.2-0.00.3-0.40.4-0.4-0.5-0.3-0.2-0.30.3-0.4-0.4-0.3-0.4-0.40.5-0.3
Time in familiar zone, hab. session 20.30.30.90.0-0.2-0.00.2-0.20.2-0.1-0.20.10.3-0.40.9-0.90.90.80.80.70.4-0.40.80.70.80.70.70.40.7
Time in novel zone, hab. session 20.40.41.0-0.30.10.1-0.10.1-0.10.10.0-0.1-0.50.3-0.80.8-0.8-0.8-0.7-0.7-1.01.0-1.0-0.9-0.8-0.9-1.0-0.1-1.0
Total zone transitions, hab. session 22.43.111.2-1.91.01.3-0.9-0.90.7-0.5-0.90.4-2.60.5-1.21.2-1.3-1.4-1.2-1.0-3.33.3-2.2-2.2-2.1-2.3-2.40.1-2.6
Total locomotion distance, hab. session 21.31.64.1-0.3-0.4-0.20.40.4-0.50.60.5-0.7-1.11.3-1.41.4-1.4-1.6-1.3-1.1-2.02.0-1.7-1.7-1.6-1.8-1.80.3-1.8
Locomotion velocity, hab. session 21.41.93.5-0.1-0.5-0.40.50.6-0.70.80.7-0.8-1.01.5-1.61.6-1.6-1.8-1.5-1.3-1.91.9-1.8-1.8-1.7-1.8-1.80.3-1.8
Novel to familiar place preference ratio0.60.72.2-1.11.51.1-1.4-0.90.8-1.0-1.11.0-1.3-0.6-0.30.3-0.2-0.4-0.3-0.5-0.70.7-0.6-0.5-1.0-0.5-0.6-0.7-0.7
Novelty place preference0.50.51.3-0.71.00.7-1.0-0.50.4-0.6-0.70.6-1.1-0.2-0.50.5-0.5-0.7-0.6-0.7-0.60.6-0.7-0.7-1.1-0.7-0.7-0.6-0.7
Time in novel zone, NPP test0.40.41.0-0.60.80.6-0.8-0.40.3-0.4-0.60.4-1.0-0.1-0.50.5-0.5-0.6-0.6-0.7-0.70.7-0.7-0.7-1.0-0.7-0.7-0.5-0.7
Total zone transitions, NPP test1.01.43.8-2.01.51.8-1.5-1.61.5-1.4-1.31.3-1.7-0.70.2-0.20.10.10.30.5-1.91.9-0.6-0.5-0.3-0.6-0.81.0-0.9
Total locomotion distance, NPP test0.20.21.1-0.3-0.10.10.1-0.0-0.00.10.3-0.2-0.20.4-0.40.4-0.5-0.5-0.2-0.1-1.01.0-0.6-0.6-0.2-0.6-0.61.0-0.7
Locomotion velocity, NPP test0.10.21.0-0.30.00.2-0.0-0.10.10.00.2-0.0-0.30.3-0.40.4-0.4-0.5-0.2-0.0-0.90.9-0.5-0.5-0.2-0.5-0.61.0-0.6
Intraocular pressure0.50.83.11.3-0.7-1.40.71.0-0.90.70.5-0.71.10.20.1-0.10.1-0.0-0.4-0.31.8-1.80.60.50.40.60.8-1.20.9
Delta distance traveled before/after self-admin0.20.20.60.4-0.4-0.30.30.2-0.10.10.1-0.10.7-0.30.5-0.50.50.60.40.40.6-0.60.60.60.80.60.60.30.7
Delta ambulatory time before/after self-admin0.20.20.70.2-0.2-0.10.2-0.00.1-0.0-0.10.00.5-0.30.7-0.70.60.60.50.50.5-0.50.70.60.80.60.60.70.7
Parametrial fat weight2.55.911.63.0-3.1-3.43.13.3-3.33.22.8-3.21.72.6-2.42.4-2.2-2.4-2.9-2.70.6-0.6-1.5-1.5-1.3-1.4-1.1-2.3-0.9
Pavlov. Cond. lever latency0.10.20.40.6-0.5-0.50.50.5-0.50.50.5-0.40.60.4-0.40.4-0.3-0.3-0.0-0.20.6-0.60.00.10.10.10.10.30.2
Pavlov. Cond. magazine entry latency0.60.81.5-0.70.60.4-0.6-0.20.1-0.2-0.30.2-1.20.3-0.90.9-1.0-0.8-0.7-0.7-1.21.2-1.2-1.1-1.2-1.1-1.2-1.2-1.2
Pavlov. Cond. change in total contacts0.40.41.8-0.40.80.3-0.8-0.20.1-0.3-0.10.4-0.90.2-0.70.7-0.8-0.6-0.7-0.6-0.40.4-0.7-0.6-1.0-0.6-0.6-1.3-0.6
Pavlov. Cond. index score0.10.10.6-0.40.60.4-0.6-0.40.3-0.4-0.30.4-0.5-0.20.0-0.0-0.10.0-0.1-0.0-0.20.2-0.2-0.1-0.3-0.1-0.1-0.8-0.2
Pavlov. Cond. latency score0.10.10.5-0.30.40.3-0.4-0.20.2-0.2-0.20.2-0.5-0.0-0.10.1-0.2-0.1-0.3-0.2-0.40.4-0.3-0.3-0.4-0.3-0.3-0.7-0.3
Pavlov. Cond. lever contacts0.10.10.6-0.30.20.2-0.2-0.20.2-0.1-0.20.1-0.4-0.10.0-0.0-0.00.1-0.2-0.1-0.60.6-0.2-0.2-0.1-0.2-0.3-0.8-0.3
Pavlov. Cond. magazine entry number0.20.20.90.5-0.9-0.60.90.5-0.50.70.5-0.70.50.4-0.10.10.0-0.1-0.2-0.2-0.10.1-0.0-0.10.1-0.1-0.10.8-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.70.6-0.3-0.40.30.4-0.30.30.6-0.20.80.20.1-0.10.10.2-0.0-0.00.6-0.60.40.40.30.40.5-0.10.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.7-0.60.80.6-0.8-0.50.5-0.6-0.50.6-0.7-0.3-0.10.1-0.2-0.0-0.1-0.0-0.40.4-0.3-0.2-0.3-0.2-0.3-0.7-0.3
Pavlov. Cond. response bias0.10.10.6-0.40.80.5-0.7-0.50.5-0.6-0.40.6-0.3-0.40.2-0.20.00.20.20.30.0-0.00.10.20.10.20.1-0.60.1
Pavlov. Cond. lever latency0.30.51.40.9-1.2-1.01.20.9-0.91.00.8-1.00.40.7-0.40.4-0.4-0.6-0.4-0.4-0.00.0-0.3-0.3-0.3-0.3-0.30.6-0.2
Pavlov. Cond. magazine entry latency2.63.18.4-2.92.82.7-2.7-2.52.4-2.4-2.42.3-2.9-1.40.5-0.50.40.50.70.6-1.91.9-0.6-0.6-0.5-0.6-0.8-0.1-1.0
Pavlov. Cond. change in total contacts1.01.65.1-1.82.31.8-2.2-1.51.4-1.6-1.41.6-2.0-0.5-0.30.3-0.4-0.3-0.3-0.3-1.21.2-0.8-0.7-0.9-0.7-0.9-1.4-1.0
Pavlov. Cond. index score1.41.95.7-2.22.42.2-2.3-1.91.8-1.9-1.81.9-2.0-1.10.3-0.30.20.40.40.4-1.21.2-0.4-0.3-0.4-0.4-0.5-0.6-0.7
Pavlov. Cond. latency score1.21.65.1-2.02.22.0-2.2-1.81.7-1.8-1.71.8-1.9-1.10.3-0.30.20.40.40.4-0.90.9-0.3-0.2-0.3-0.3-0.4-0.4-0.5
Pavlov. Cond. lever contacts0.30.41.5-0.91.21.1-1.2-0.90.9-1.0-0.91.0-0.6-0.70.3-0.30.20.50.20.3-0.20.20.10.10.10.10.1-0.7-0.0
Pavlov. Cond. magazine entry number3.94.812.93.5-3.6-3.43.53.1-3.03.13.0-3.13.31.9-0.80.8-0.7-0.8-1.0-0.92.0-2.00.40.30.40.40.70.10.9
Pavlov. Cond. intertrial magazine entries0.60.92.11.4-1.3-1.41.31.4-1.31.31.4-1.31.11.2-0.70.7-0.7-0.8-0.6-0.60.8-0.8-0.2-0.2-0.3-0.1-0.0-0.30.1
Pavlov. Cond. lever-magazine prob. diff.1.72.36.7-2.42.62.4-2.5-2.12.0-2.1-2.02.1-2.3-1.30.4-0.40.30.40.50.4-1.31.3-0.4-0.3-0.3-0.4-0.6-0.5-0.7
Pavlov. Cond. response bias1.11.54.5-2.02.11.9-2.1-1.71.7-1.7-1.71.7-1.8-1.00.3-0.30.20.40.30.3-1.11.1-0.3-0.3-0.3-0.3-0.5-0.9-0.6
Time in closed arm before self-admin0.70.92.30.5-0.3-0.80.30.8-0.80.70.8-0.7-0.31.3-1.41.4-1.5-1.4-1.2-1.1-0.20.2-1.1-1.1-1.3-1.0-1.0-0.7-0.9
Time in closed arm after self-admin0.10.10.30.3-0.4-0.60.40.4-0.40.40.3-0.40.10.3-0.20.2-0.3-0.3-0.2-0.20.0-0.0-0.2-0.2-0.1-0.2-0.20.0-0.2
Time in open arm before self-admin0.70.74.80.4-1.1-0.21.10.2-0.20.40.3-0.51.3-0.30.8-0.80.90.71.00.70.1-0.10.90.81.30.70.82.20.8
Time in open arm after self-admin0.20.20.5-0.20.00.2-0.1-0.30.3-0.3-0.40.3-0.1-0.40.5-0.50.70.70.60.50.1-0.10.50.50.50.40.4-0.50.4
Bone: periosteal estimation0.20.31.00.00.1-0.0-0.10.3-0.30.20.3-0.2-0.20.3-1.01.0-1.0-0.8-0.6-0.7-0.20.2-0.8-0.7-0.8-0.7-0.7-0.4-0.7
Bone: periosteal perimeter0.40.71.5-0.50.80.4-0.7-0.10.0-0.2-0.00.2-0.80.5-1.21.2-1.2-1.1-0.8-0.9-0.70.7-1.2-1.0-1.2-1.0-1.1-0.7-1.1
Bone: post-yield work5.17.517.7-1.61.30.9-1.1-0.2-0.1-0.0-0.4-0.0-3.51.3-3.23.2-3.2-3.2-2.8-2.8-3.43.4-3.8-3.8-4.2-3.8-3.9-1.4-4.0
Progressive ratio test 1 active lever presses0.20.20.80.1-0.1-0.20.10.3-0.30.30.1-0.3-0.20.1-0.80.8-0.7-0.8-0.9-0.4-0.40.4-0.6-0.6-0.5-0.6-0.6-0.1-0.6
Progressive ratio test 1 breakpoint0.20.20.7-0.00.0-0.20.00.2-0.20.20.1-0.2-0.30.1-0.70.7-0.6-0.7-0.9-0.4-0.40.4-0.6-0.6-0.5-0.6-0.6-0.1-0.6
Progressive ratio test 1 inactive lever presses0.10.10.30.00.0-0.2-0.00.1-0.20.1-0.0-0.1-0.40.3-0.50.5-0.4-0.5-0.5-0.5-0.10.1-0.4-0.4-0.5-0.4-0.4-0.2-0.4
Progressive ratio test 2 active lever presses1.72.03.81.2-1.0-1.41.11.5-1.61.41.3-1.40.21.6-1.91.9-1.9-1.9-1.9-1.70.1-0.1-1.3-1.3-1.3-1.2-1.1-1.3-1.0
Progressive ratio test 2 breakpoint1.51.83.41.2-1.0-1.41.01.5-1.51.41.3-1.40.21.5-1.81.8-1.8-1.8-1.8-1.60.1-0.1-1.2-1.2-1.2-1.1-1.0-1.3-0.9
Progressive ratio test 2 inactive lever presses4.37.011.32.9-2.7-3.12.83.3-3.43.23.0-3.21.23.2-3.23.2-3.2-3.2-3.2-3.10.7-0.7-2.0-1.9-1.9-1.8-1.6-1.8-1.3
Incentive Sensitization - Responses0.50.61.5-0.30.30.1-0.30.0-0.10.1-0.1-0.1-1.00.6-0.90.9-1.0-1.0-0.9-0.9-0.70.7-1.1-1.1-1.2-1.1-1.1-1.2-1.1
Incentive Sensitization - Breakpoint0.50.71.8-0.10.2-0.1-0.10.2-0.30.20.1-0.3-0.80.8-1.01.0-1.1-1.1-0.9-1.0-0.60.6-1.1-1.1-1.2-1.1-1.1-1.4-1.0
Sum of active levers in priming session hrs 5-62.92.74.2-0.72.01.5-2.0-1.41.6-1.9-1.32.00.1-1.81.5-1.51.71.61.61.62.0-2.01.81.91.42.01.9-0.21.9
Progressive ratio1.52.37.5-1.60.90.9-0.8-0.70.6-0.4-1.00.4-2.30.0-1.01.0-1.1-1.1-1.2-1.2-2.72.7-1.9-2.0-2.0-2.0-2.2-1.0-2.3
Food seeking constrained by brief footshock0.10.20.4-0.50.30.4-0.3-0.50.5-0.4-0.50.4-0.2-0.20.6-0.60.60.40.50.5-0.40.40.30.30.30.20.20.50.1
Seeking ratio, punishment vs. effort1.31.85.11.6-1.4-1.11.31.0-0.80.81.3-0.82.30.50.7-0.70.80.70.90.92.0-2.01.51.51.71.51.71.81.8
Retroperitoneal fat weight5.925.250.06.9-6.8-6.96.97.1-7.06.96.9-6.94.95.9-4.84.8-4.7-4.5-4.4-4.62.4-2.4-2.2-2.1-1.8-1.9-1.4-2.9-0.9
Reaction time number correct0.40.81.3-0.20.60.7-0.6-0.60.7-0.7-0.40.80.3-0.71.1-1.11.01.01.11.10.9-0.91.11.11.01.11.10.41.1
Reaction time mean minus median1.12.67.1-2.42.72.1-2.6-2.32.3-2.4-2.52.4-2.2-1.91.0-1.00.90.91.00.9-1.01.00.20.2-0.20.2-0.0-0.1-0.2
Reaction time mean minus median AUC0.71.93.6-1.61.91.6-1.9-1.81.9-1.9-1.91.9-1.1-1.71.4-1.41.41.31.31.2-0.10.10.90.80.50.80.70.40.6
Reaction time num false alarms0.60.93.20.7-0.9-0.50.80.3-0.20.40.4-0.41.4-0.30.8-0.80.90.71.01.01.0-1.01.11.11.51.11.11.81.1
Reaction time num false alarms AUC0.61.04.9-0.0-0.20.20.1-0.40.5-0.3-0.40.30.7-0.81.1-1.11.31.11.41.40.7-0.71.21.21.61.11.12.21.1
Reaction time trials correct on left0.40.81.3-0.20.60.7-0.6-0.60.7-0.7-0.40.80.3-0.71.1-1.11.01.01.11.10.9-0.91.11.11.01.11.10.41.1
Reaction time trials on left0.51.01.6-0.30.70.8-0.7-0.70.8-0.9-0.50.90.3-0.81.2-1.21.11.21.31.20.9-0.91.21.21.21.21.20.51.2
Reaction time mean0.00.10.3-0.20.3-0.0-0.3-0.20.2-0.2-0.40.2-0.4-0.1-0.10.1-0.2-0.1-0.2-0.1-0.30.3-0.2-0.2-0.3-0.2-0.2-0.5-0.2
Reaction time mean AUC0.10.10.3-0.20.3-0.1-0.3-0.10.1-0.1-0.20.1-0.50.1-0.30.3-0.4-0.3-0.3-0.3-0.30.3-0.3-0.4-0.5-0.3-0.3-0.5-0.3
Median of all reaction times0.20.20.60.3-0.3-0.60.40.5-0.50.50.3-0.5-0.10.6-0.60.6-0.7-0.6-0.7-0.6-0.30.3-0.5-0.5-0.5-0.5-0.4-0.8-0.4
Reaction time omissions1.31.94.7-1.81.91.6-1.9-1.91.9-1.9-2.21.9-1.3-1.91.3-1.31.41.21.01.0-0.50.50.70.60.60.60.40.20.3
Reaction time false alarm rate0.30.42.70.4-0.7-0.50.70.2-0.10.30.1-0.30.8-0.30.4-0.40.60.40.70.70.4-0.40.60.50.90.50.51.70.6
Reaction time premature initiation rate1.72.34.0-1.81.31.8-1.4-2.02.0-1.8-1.51.8-0.7-1.61.7-1.71.71.82.01.9-0.90.91.11.11.21.00.81.90.7
Reaction time premature initiations2.54.47.7-2.12.02.5-2.0-2.52.6-2.5-2.02.5-0.6-2.22.5-2.52.42.52.82.7-0.30.31.91.81.91.71.52.21.4
Std. dev. reaction times0.40.72.3-1.31.40.9-1.4-1.21.2-1.3-1.51.3-1.2-1.10.5-0.50.40.50.40.4-0.60.60.10.1-0.10.1-0.0-0.2-0.1
Reaction time trials completed0.51.01.6-0.30.70.8-0.7-0.70.8-0.9-0.50.90.3-0.81.2-1.21.11.21.31.20.9-0.91.21.21.21.21.20.51.2
Reaction time trials AUC0.40.71.2-0.20.50.6-0.5-0.50.6-0.7-0.30.70.4-0.61.0-1.01.01.01.11.10.8-0.81.11.11.11.11.10.51.0
Run reversals in cocaine runway, females0.30.31.5-0.80.10.5-0.1-0.50.4-0.2-0.60.1-1.0-0.00.1-0.10.00.10.0-0.2-1.21.2-0.5-0.6-0.3-0.7-0.8-0.6-0.8
Run reversals in cocaine runway, males1.71.74.10.8-0.4-0.40.40.10.0-0.10.10.11.5-0.51.4-1.41.41.31.31.32.0-2.01.91.81.81.91.90.52.0
Latency to leave start box in cocaine runway0.80.92.1-0.20.0-0.20.00.3-0.40.30.2-0.4-1.00.9-1.21.2-1.2-1.2-1.1-1.2-1.01.0-1.3-1.3-1.4-1.3-1.3-0.9-1.3
Latency to leave start box in cocaine runway, F0.50.51.1-0.1-0.1-0.10.10.2-0.30.30.2-0.3-0.70.7-0.90.9-0.8-0.8-0.8-1.0-0.90.9-1.0-0.9-1.1-1.0-1.0-0.5-1.0
Latency to leave start box in cocaine runway, M0.20.10.5-0.40.50.2-0.5-0.20.2-0.3-0.30.3-0.70.1-0.40.4-0.3-0.4-0.3-0.3-0.30.3-0.4-0.4-0.5-0.4-0.4-0.3-0.5
Std. dev. time between licks in bursts0.71.04.90.3-0.7-0.20.7-0.00.10.10.0-0.11.2-0.71.1-1.11.11.11.21.20.6-0.61.21.21.81.11.12.21.1
Total sessions with >9 infusions0.70.82.0-0.60.20.3-0.1-0.1-0.10.1-0.2-0.2-1.00.1-1.01.0-0.9-1.0-1.1-0.8-1.41.4-1.3-1.3-1.1-1.3-1.4-0.6-1.4
Short access day 1 total inactive lever presses1.41.83.41.7-1.8-1.51.81.8-1.81.81.8-1.81.11.6-1.31.3-1.4-1.2-1.5-1.40.3-0.3-0.8-0.7-0.6-0.7-0.5-1.4-0.4
Short access day 10 total inactive lever presses0.10.20.80.5-0.6-0.70.60.5-0.50.50.3-0.50.20.60.0-0.0-0.1-0.0-0.1-0.20.4-0.4-0.0-0.1-0.0-0.00.0-0.90.0
Short access day 1 total infusions1.72.34.41.0-1.4-1.21.41.5-1.61.61.3-1.60.11.5-1.91.9-1.9-1.7-2.0-1.9-0.60.6-1.6-1.6-1.3-1.5-1.5-2.1-1.4
Short access day 10 total infusions2.83.67.2-0.4-0.2-0.10.30.6-0.80.80.2-0.9-1.71.1-2.32.3-2.3-2.3-2.5-2.2-2.22.2-2.6-2.6-2.4-2.6-2.7-1.5-2.7
Short access total infusions1.31.63.1-0.1-0.5-0.30.50.6-0.70.80.3-0.8-0.80.7-1.61.6-1.5-1.5-1.8-1.4-1.51.5-1.7-1.7-1.4-1.8-1.8-1.2-1.8
Short access day 1 locomotion1.31.73.00.7-0.9-1.01.01.2-1.21.20.9-1.3-0.21.3-1.71.7-1.5-1.7-1.7-1.7-0.50.5-1.4-1.5-1.4-1.4-1.4-1.5-1.3
Short access day 10 total locomotion1.01.83.20.6-0.7-0.90.81.1-1.21.20.8-1.2-0.51.5-1.71.7-1.8-1.8-1.6-1.8-0.60.6-1.6-1.6-1.7-1.6-1.5-1.7-1.4
Short access total locomotion1.72.03.70.8-0.9-0.91.01.3-1.31.31.0-1.3-0.31.5-1.91.9-1.8-1.9-1.8-1.8-0.60.6-1.6-1.6-1.6-1.6-1.5-1.4-1.5
One hour access (0.3 mA shock)3.84.48.02.5-2.5-2.82.52.8-2.82.72.5-2.71.22.5-2.22.2-2.3-2.3-2.3-2.10.8-0.8-1.4-1.4-1.3-1.3-1.1-1.7-0.9
Compulsive drug intake2.53.05.8-1.10.71.4-0.8-1.61.7-1.5-1.21.40.5-1.82.4-2.42.42.32.42.30.1-0.11.91.92.21.81.72.41.6
One hour access (shock baseline)4.06.19.72.7-2.3-3.02.43.1-3.12.92.7-2.90.92.9-2.92.9-3.0-3.0-3.0-2.90.9-0.9-1.9-1.9-2.0-1.7-1.5-2.6-1.3
Social response proportion0.40.52.1-1.01.10.8-1.1-0.80.8-0.8-0.80.8-1.40.0-0.20.2-0.1-0.40.10.0-0.80.8-0.5-0.5-0.7-0.5-0.60.7-0.6
Social responses0.20.30.9-0.60.50.6-0.5-0.60.6-0.6-0.60.6-0.3-0.30.5-0.50.60.40.60.5-0.20.20.30.30.20.30.31.00.2
Social time0.30.40.8-0.60.50.7-0.5-0.70.7-0.7-0.70.7-0.0-0.70.8-0.80.90.70.90.80.0-0.00.60.60.50.60.50.80.5
Soleus weight2.36.816.54.1-4.1-3.84.03.8-3.73.74.0-3.73.52.8-1.51.5-1.4-1.4-1.4-1.42.2-2.2-0.1-0.00.20.00.4-0.60.6
Bone: stiffness1.42.26.6-2.32.32.1-2.2-1.71.6-1.6-1.71.6-2.6-0.7-0.40.4-0.4-0.3-0.3-0.3-1.91.9-1.2-1.1-1.3-1.2-1.4-0.7-1.5
Tibialis anterior weight7.726.144.5-5.76.26.4-6.3-6.66.7-6.7-6.36.7-2.8-6.55.5-5.55.55.65.55.5-0.10.13.83.83.63.63.12.52.7
Time to tail flick, vehicle, before self-admin0.20.20.7-0.60.30.3-0.3-0.30.3-0.2-0.40.2-0.90.1-0.20.2-0.3-0.2-0.2-0.2-0.80.8-0.6-0.6-0.6-0.6-0.6-0.3-0.7
Time to tail flick, vehicle, after self-admin0.70.93.7-1.10.30.5-0.3-0.60.4-0.3-0.90.2-1.5-0.3-0.40.4-0.5-0.5-0.4-0.4-1.91.9-1.1-1.2-1.0-1.2-1.3-0.3-1.4
Time to tail flick, test, before self-admin2.22.33.80.9-1.6-1.41.71.5-1.61.71.4-1.8-0.11.9-1.91.9-1.8-1.9-1.7-1.5-1.11.1-1.6-1.6-1.1-1.6-1.60.3-1.5
Time to tail flick, test, after self-admin0.10.10.5-0.10.40.0-0.4-0.10.1-0.2-0.20.3-0.3-0.2-0.10.1-0.2-0.1-0.20.00.3-0.3-0.0-0.0-0.10.00.0-0.70.0
Delta time to tail flick, vehicle, before/after SA0.40.41.4-0.90.50.5-0.4-0.60.5-0.4-0.80.3-1.1-0.2-0.20.2-0.2-0.3-0.1-0.1-1.21.2-0.6-0.6-0.5-0.7-0.7-0.1-0.8
Delta time to tail flick, test, before/after SA3.43.55.6-0.81.71.2-1.7-1.51.7-1.9-1.51.90.4-2.42.2-2.22.22.32.12.01.9-1.92.22.21.72.22.2-0.02.1
Tibia length0.82.34.7-1.42.21.9-2.2-1.81.8-2.1-1.42.1-0.3-2.01.2-1.21.21.31.41.50.9-0.91.21.31.01.31.21.31.1
Ambulatory time before self-admin0.50.82.5-0.81.10.7-1.0-0.50.4-0.6-0.60.6-1.60.2-0.70.7-0.8-0.7-0.7-0.6-0.90.9-1.0-0.9-1.3-0.9-1.0-1.4-1.0
Ambulatory time after self-admin0.91.03.10.3-0.0-0.50.10.6-0.70.60.3-0.6-0.81.0-1.31.3-1.5-1.3-1.4-1.4-0.40.4-1.2-1.2-1.4-1.1-1.1-1.8-1.1
Bone: tissue strength0.10.10.3-0.20.20.1-0.20.0-0.10.00.1-0.0-0.40.3-0.50.5-0.6-0.4-0.5-0.4-0.40.4-0.5-0.5-0.5-0.5-0.5-0.3-0.5
Total heroin consumption2.83.37.6-2.52.62.8-2.6-2.62.5-2.6-2.52.6-1.6-2.31.4-1.41.51.21.61.5-1.01.00.70.70.50.60.41.10.2
Bone: trabecular number1.52.56.3-1.71.41.3-1.3-0.90.7-0.7-1.20.7-2.4-0.3-1.21.2-1.3-1.2-1.2-1.3-2.52.5-2.0-2.0-1.9-2.0-2.1-1.5-2.2
Bone: trabecular spacing0.40.51.41.0-1.2-0.81.10.7-0.60.70.8-0.71.20.50.4-0.40.40.40.30.40.7-0.70.70.60.80.60.70.70.8
Bone: trabecular thickness1.31.62.90.1-0.3-0.50.40.7-0.80.80.7-0.8-0.61.0-1.71.7-1.7-1.4-1.4-1.6-1.31.3-1.7-1.7-1.6-1.7-1.6-1.5-1.6
Bone: trabecular tissue density2.23.28.52.9-2.3-2.62.32.5-2.42.22.6-2.22.71.5-1.01.0-1.0-0.9-0.7-0.82.4-2.40.30.40.60.50.7-0.71.0
Water consumed over 24 hours0.50.71.6-1.21.11.3-1.1-1.21.2-1.1-1.11.1-0.9-0.80.5-0.50.50.70.80.6-0.70.70.20.20.10.10.01.1-0.1
Number of responses in last shaping day0.10.10.40.1-0.3-0.10.2-0.00.00.0-0.1-0.00.2-0.10.5-0.50.50.40.20.40.1-0.10.40.40.60.30.4-0.10.4