Hub : Genes

Zdhhc24

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Zdhhc24 0.42 0.17 3.1e-04 -0 0.06 -0 0.02 3.6e-01 4.9e-02 3.5e-01 1.6e-01
2 NAcc gene expression Zdhhc24 0.1 0.06 1.5e-10 0.09 0.09 0.09 0.09 5.1e-10 5.6e-11 1.4e-10 1.2e-10
3 PL gene expression Zdhhc24 0.13 0.07 5.6e-17 0.14 0.16 0.13 0.15 1.8e-15 8.4e-17 5.8e-14 1.5e-16
4 Liver gene expression Zdhhc24 0.06 0.04 4.3e-03 0.02 0.01 0.01 0.01 3.7e-03 2.0e-02 3.7e-02 1.5e-02
5 BLA gene expression Zdhhc24 0.19 0.11 3.2e-08 0.14 0.14 0.13 0.14 9.4e-08 1.1e-07 1.2e-07 7.8e-08
6 Adipose gene expression Zdhhc24 0.32 0.13 6.9e-03 0 0 0.02 0 1.4e-01 1.4e-01 2.3e-03 2.9e-01
7 pVTA gene expression Zdhhc24 0.14 0.08 4.8e-05 0.04 0.06 0.04 0.04 5.1e-03 1.3e-03 4.9e-03 1.0e-02
8 Brain mRNA stability Zdhhc24 0.06 0.04 2.6e-05 0.02 0.05 0.05 0.04 3.5e-03 4.2e-05 2.3e-05 6.7e-05
9 BLA mRNA stability Zdhhc24 0.07 0.05 4.5e-03 0.01 0.03 0 0.01 1.1e-01 1.5e-02 1.7e-01 1.2e-01
10 Brain gene expression Zdhhc24 0.1 0.06 4.1e-09 0.09 0.09 0.1 0.08 9.6e-09 2.3e-08 3.8e-09 3.0e-08
11 OFC gene expression Zdhhc24 0.19 0.14 9.3e-03 0 0.03 0.03 -0.01 3.0e-01 6.1e-02 6.2e-02 5.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density2.44.07.50.5-1.2-1.42.7-1.72.2-2.12.1-2.42.4-2.3
Area under the delay curve1.01.12.10.8-0.9-1.10.7-1.50.5-1.11.0-1.20.9-1.3
BMI with tail1.85.915.8-1.0-0.2-0.73.6-1.84.0-2.22.0-2.92.4-2.8
BMI without tail0.71.54.9-0.60.1-0.31.6-0.72.2-1.01.1-1.41.1-1.5
Body weight0.83.311.4-3.42.52.12.11.12.90.6-0.5-0.1-0.2-0.0
Weight adjusted by age1.11.33.3-1.81.51.50.31.10.81.0-1.20.7-0.70.9
Bone surface1.93.412.2-1.20.1-0.03.5-1.03.1-1.31.3-1.92.0-1.5
Bone volume1.93.29.3-0.2-0.7-0.83.1-1.42.2-1.71.7-2.12.2-1.7
Breakpoint value in progressive ratio session1.01.13.4-1.81.31.41.00.81.50.7-0.60.3-0.30.6
Number of licking bursts0.10.10.9-0.40.20.20.6-0.10.9-0.0-0.1-0.10.20.0
Context. condit. distance diff. score0.60.72.21.5-1.1-1.1-0.7-0.6-0.5-0.60.8-0.30.4-0.5
Locomotion velocity, session 10.40.41.0-0.30.60.5-1.00.6-0.30.7-0.70.7-0.90.6
Locomotion distance, session 11.01.24.4-0.0-0.3-0.61.2-1.02.1-1.11.0-1.31.0-1.3
Locomotion velocity, session 20.50.62.3-1.51.10.90.90.50.90.3-0.4-0.1-0.1-0.0
Locomotion distance, session 20.30.51.7-0.60.3-0.00.9-0.41.3-0.50.5-0.80.4-0.9
Locomotion velocity, session 30.40.40.70.5-0.6-0.70.4-0.80.4-0.80.6-0.80.6-0.8
Locomotion distance, session 30.00.00.00.1-0.1-0.10.0-0.0-0.1-0.1-0.0-0.00.0-0.1
Stereotopy head waving bouts, day 30.70.91.41.1-1.0-1.20.1-1.00.3-1.01.0-0.90.8-1.2
Stereotopy head waving duration, day 30.91.11.91.4-1.3-1.40.1-1.20.1-1.11.1-1.00.9-1.1
Locomotion velocity, session 71.01.01.70.8-1.0-1.10.6-1.10.0-1.21.1-1.21.0-1.3
Locomotion distance, session 70.10.10.40.1-0.0-0.3-0.1-0.10.1-0.30.3-0.40.0-0.7
Stereotopy head waving bouts, day 71.21.32.10.9-1.2-1.11.2-1.20.7-1.21.3-1.11.5-1.0
Stereotopy head waving duration, day 71.31.54.8-0.2-0.5-0.52.2-1.01.6-1.11.0-1.31.6-1.1
Locomotion velocity, session 80.70.81.6-1.21.21.1-0.21.00.40.9-1.10.7-0.80.6
Locomotion distance, session 80.30.40.50.7-0.7-0.70.0-0.70.5-0.60.7-0.60.5-0.6
Degree of sensitization distance0.20.20.70.2-0.2-0.50.3-0.50.4-0.60.6-0.70.4-0.8
Degree of sensitization stereotypy0.60.62.5-0.2-0.3-0.21.6-0.51.0-0.60.7-0.81.1-0.5
Conditioned locomotion1.61.93.7-1.91.91.8-0.31.80.41.5-0.81.3-1.21.1
Cocaine response after cond. corrected0.20.20.80.9-0.6-0.7-0.8-0.2-0.2-0.20.30.0-0.0-0.3
Cocaine response after cond. not corrected0.30.31.01.0-0.7-0.8-0.4-0.60.1-0.50.4-0.30.3-0.5
Cocaine response before conditioning0.20.21.2-0.40.00.11.1-0.50.4-0.30.1-0.40.5-0.1
Saline control response0.70.93.5-1.91.41.21.10.61.10.4-0.6-0.1-0.2-0.0
Bone: connectivity density2.43.710.7-0.6-0.4-0.63.1-1.23.3-1.71.7-2.12.1-2.0
Bone: cortical apparent density0.30.40.6-0.80.80.7-0.20.70.60.6-0.50.5-0.50.5
Bone: cortical area0.60.91.7-1.31.21.30.11.2-0.41.0-0.80.8-0.71.0
Bone: cortical porosity0.50.61.00.2-0.5-0.60.9-0.70.6-0.90.8-1.00.8-1.0
Bone: cortical porosity0.20.30.7-0.30.1-0.10.8-0.20.6-0.50.4-0.70.5-0.7
Bone: cortical thickness4.06.510.5-3.23.23.2-0.83.1-0.22.7-2.52.4-2.32.4
Bone: cortical thickness2.63.04.4-1.82.11.9-1.22.1-0.41.9-2.01.8-1.81.5
Bone: cortical tissue density0.40.50.8-0.90.90.8-0.20.80.60.7-0.60.6-0.60.5
Condit. Reinf. active minus inactive responses0.20.20.6-0.1-0.1-0.10.8-0.60.6-0.40.7-0.50.4-0.4
Condit. Reinf. active-inactive response ratio0.20.20.40.1-0.3-0.20.6-0.60.6-0.30.6-0.40.4-0.2
Condit. Reinf. active responses0.10.10.5-0.1-0.0-0.00.6-0.50.3-0.20.7-0.30.2-0.2
Condit. Reinf. inactive responses0.00.10.20.1-0.2-0.20.2-0.3-0.2-0.20.5-0.20.1-0.2
Incentive salience index mean0.20.30.8-0.2-0.0-0.10.9-0.50.7-0.40.7-0.60.4-0.5
Condit. Reinf. lever presses0.10.10.3-0.50.30.40.40.20.20.20.10.1-0.10.3
Condit. Reinf. active minus inactive responses1.01.32.11.0-1.3-1.11.1-1.50.6-1.20.9-1.21.3-0.9
Condit. Reinf. active-inactive response ratio1.01.02.11.3-1.5-1.10.6-1.4-0.2-1.01.0-0.91.0-0.5
Condit. Reinf. active responses1.62.23.30.7-1.2-1.21.8-1.71.6-1.61.2-1.71.8-1.5
Condit. Reinf. inactive responses1.21.53.60.0-0.4-0.71.6-0.91.9-1.20.7-1.51.3-1.6
Condit. Reinf. lever presses0.60.84.0-1.20.50.52.0-0.21.3-0.30.1-0.70.7-0.2
Condit. Reinf. lever reinforcers received1.31.83.70.4-0.9-0.91.9-1.41.6-1.41.0-1.61.6-1.3
Conditioned reinforcement - actives0.10.10.30.3-0.20.0-0.4-0.0-0.60.2-0.10.3-0.20.4
Conditioned reinforcement - inactives1.92.16.42.5-2.1-1.8-0.8-1.4-1.9-0.91.1-0.40.7-0.3
Conditioned locomotion2.12.58.92.6-1.8-1.5-2.3-0.6-3.0-0.20.10.4-0.30.3
Patch foraging indifference point 0 sec0.20.40.70.5-0.7-0.60.5-0.80.7-0.60.6-0.60.7-0.5
Patch foraging indifference point AUC1.41.64.5-2.11.71.60.81.31.80.9-0.80.6-0.50.7
Delay disc. indifference point, 0s delay0.80.92.01.1-0.9-1.30.0-1.00.4-1.10.8-1.00.6-1.4
Delay disc. indifference point, 16s delay1.91.93.41.5-1.6-1.51.2-1.8-0.2-1.41.4-1.21.5-1.1
Delay disc. indifference point, 2s delay0.20.30.60.6-0.6-0.6-0.0-0.70.2-0.60.4-0.50.3-0.5
Delay disc. indifference point, 24s delay0.10.10.3-0.00.30.2-0.10.1-0.60.3-0.00.4-0.30.1
Delay disc. indifference point, 4s delay0.40.51.20.6-0.5-0.80.1-0.90.3-0.80.6-0.80.5-1.1
Delay disc. indifference point, 8s delay0.30.30.90.5-0.4-0.70.1-0.80.2-0.70.5-0.70.4-1.0
Indifference point function ln k2.23.09.13.0-2.1-2.0-2.3-1.1-2.9-0.70.5-0.0-0.1-0.4
Indifference point function log k2.23.09.13.0-2.1-2.0-2.3-1.1-2.9-0.70.5-0.0-0.1-0.4
Patch foraging total patch changes 0 sec0.00.00.10.1-0.1-0.0-0.1-0.20.40.00.00.10.10.1
Patch foraging total patch changes 12 sec1.51.98.1-2.21.61.41.60.82.90.4-0.4-0.10.20.1
Patch foraging total patch changes 18 sec0.50.74.5-0.60.20.11.1-0.12.1-0.30.5-0.50.7-0.5
Patch foraging total patch changes 24 sec1.31.64.5-1.91.61.50.41.12.11.0-0.90.7-0.60.7
Patch foraging total patch changes 6 sec0.60.85.0-1.00.50.41.2-0.02.2-0.20.4-0.50.6-0.5
Patch foraging time to switch 0 sec1.32.07.1-0.7-0.1-0.32.7-1.01.7-1.21.4-1.61.5-1.4
Patch foraging water rate 0 sec1.32.18.61.5-0.6-0.3-2.90.6-1.81.0-1.01.6-1.21.5
Patch foraging water rate 12 sec2.33.515.02.4-1.0-0.9-3.90.4-2.90.8-1.01.5-1.51.0
Patch foraging water rate 18 sec0.71.04.01.5-0.8-0.8-2.0-0.1-1.50.1-0.30.5-0.50.2
Patch foraging water rate 24 sec1.52.18.11.5-0.6-0.4-2.80.6-2.50.8-0.81.3-1.21.0
Patch foraging water rate 6 sec1.21.88.51.2-0.2-0.2-2.90.9-1.51.0-0.91.5-1.41.1
Seeking ratio, delayed vs. immediate footshock0.60.71.10.6-0.7-0.80.6-1.10.4-1.00.6-1.00.8-1.1
Distance traveled before self-admin0.10.10.5-0.40.20.30.50.10.70.10.2-0.00.10.2
Distance traveled after self-admin0.00.00.1-0.20.10.20.3-0.10.30.00.1-0.00.10.2
Extensor digitorum longus weight2.39.229.5-5.44.54.11.93.02.92.3-2.01.2-1.51.4
Bone: elastic displacement1.61.84.1-0.20.80.8-2.01.5-1.31.4-1.21.6-1.61.3
Bone: elastic work2.12.84.4-1.82.01.8-1.22.1-0.21.8-1.71.7-1.71.4
Bone: endosteal estimation1.84.05.72.2-2.3-2.31.0-2.4-0.0-2.22.2-2.01.9-1.9
Bone: endosteal perimeter3.26.610.22.8-3.1-2.91.7-3.20.5-2.82.7-2.62.6-2.3
Epididymis fat weight1.33.07.72.8-2.5-2.3-0.5-1.7-0.9-1.61.6-1.11.3-1.2
Delta time in closed arm before/after self-admin0.50.51.0-0.70.90.6-0.81.0-0.20.7-0.50.6-0.80.3
Delta time in open arm before/after self-admin0.00.00.2-0.1-0.10.20.30.00.20.10.10.20.10.4
Diff in mean of infusions in LGA sessions0.50.51.0-1.00.90.90.30.70.50.8-0.60.7-0.40.8
Delay discount exponential model param0.70.81.7-0.70.70.9-0.61.3-0.41.0-0.81.0-0.81.1
Extinction: sum of active levers before priming1.31.36.0-1.71.11.01.80.32.40.1-0.1-0.30.4-0.1
Active lever presses in extinction session 62.12.03.5-1.91.71.9-0.11.60.21.5-1.41.3-1.21.6
Bone: final force0.50.83.2-1.81.31.31.00.70.80.5-0.20.1-0.20.4
Bone: final moment0.50.72.7-1.71.21.21.00.70.80.5-0.20.1-0.20.3
Food consumed during 24 hour testing period0.30.42.1-0.20.20.40.10.2-1.50.5-0.60.5-0.30.8
Glucose2.74.16.22.4-2.4-2.50.9-2.20.0-2.22.0-2.01.9-2.1
Heart weight1.42.04.72.2-1.9-1.9-0.2-1.1-0.2-1.31.7-0.91.2-1.2
Delay discount hyperbolic model param0.60.61.4-0.60.60.8-0.51.2-0.40.9-0.70.9-0.71.1
Intermittent access intake day 1-15 change0.50.51.70.20.00.3-0.70.5-1.30.7-0.40.9-0.51.0
Intermittent access intake escalation0.10.10.60.4-0.20.0-0.40.2-0.80.3-0.10.4-0.20.6
Intermittent access intake escalation 20.60.61.3-0.10.30.6-0.70.6-1.00.8-0.61.0-0.81.1
Intermitt. access day 1 inactive lever presses1.11.22.61.6-1.5-1.3-0.1-1.0-1.5-0.91.2-0.50.9-0.5
Intermitt. access day 15 inactive lever presses0.80.92.11.5-1.4-1.10.1-1.0-1.2-0.70.9-0.40.8-0.3
Intermitt. access escalation Index2.32.04.52.1-1.8-2.0-0.6-1.3-0.5-1.51.3-1.21.0-1.5
Intermittent access day 1 total infusions7.28.412.33.4-3.4-3.51.1-3.30.2-3.23.1-2.92.7-3.0
Intermittent access day 15 total infusions4.04.410.03.2-2.9-2.7-0.0-2.3-1.3-2.02.2-1.51.7-1.5
Intermittent access terminal intake (last 3 days)3.74.17.72.8-2.7-2.50.4-2.3-0.7-2.02.3-1.61.8-1.6
Intermittent access total infusions5.05.58.32.8-2.9-2.81.0-2.6-0.0-2.52.6-2.32.3-2.2
Intermittent access day 1 locomotion5.96.28.62.6-2.8-2.91.2-2.90.4-2.82.7-2.62.4-2.7
Intermittent access day 15 total locomotion2.83.16.42.5-2.4-2.20.2-1.9-0.7-1.71.8-1.41.6-1.3
Intermittent access total locomotion7.18.112.53.5-3.5-3.51.1-3.3-0.1-3.13.0-2.72.8-2.7
Intermittent access standard deviation0.20.21.00.7-0.5-0.3-0.7-0.1-1.00.00.10.3-0.10.3
Left kidney weight0.20.41.30.9-0.6-0.3-1.10.2-1.10.30.30.6-0.30.6
Right kidney weight0.20.62.10.20.00.5-0.60.8-0.50.9-0.61.1-0.61.4
Cocaine induced anxiety0.10.10.2-0.20.20.3-0.10.3-0.40.3-0.30.4-0.30.4
Post-drug Anxiety1.21.42.4-1.51.41.50.11.30.11.3-1.11.1-1.01.3
Baseline Anxiety1.51.63.4-1.81.71.70.21.30.91.2-1.21.0-1.01.1
Tail length1.95.77.2-2.32.72.7-1.82.7-0.62.7-2.42.6-2.62.5
Length with tail1.96.812.9-3.63.43.4-0.33.00.12.7-2.52.3-2.32.4
Length without tail1.02.26.2-2.52.12.00.71.50.71.2-1.50.7-0.91.0
Times rat made contact with spout0.30.41.8-0.40.2-0.00.9-0.31.4-0.40.4-0.50.5-0.6
Lifetime Intake4.75.37.62.6-2.7-2.81.0-2.50.3-2.52.6-2.32.2-2.3
Liver weight, left0.10.20.80.10.10.1-0.80.4-0.90.3-0.40.4-0.40.2
Liver weight, right0.10.20.90.00.20.1-0.90.4-0.60.3-0.50.3-0.60.0
Locomotor activity0.61.04.70.8-0.0-0.0-2.20.4-1.10.8-0.91.1-1.10.8
Locomotor testing distance0.71.26.11.0-0.1-0.2-2.50.4-1.20.7-1.01.1-1.20.6
Locomotor testing rearing0.50.82.41.5-1.1-1.2-1.2-0.7-0.3-0.60.4-0.30.2-0.7
Locomotion in novel chamber1.62.06.12.5-2.0-1.7-1.0-1.5-2.0-0.90.7-0.40.6-0.3
Locomotion in novel chamber post-restriction0.81.03.11.8-1.4-1.2-0.9-0.8-1.1-0.61.0-0.20.3-0.3
Fecal boli incidents, locomotor time 10.10.10.7-0.1-0.10.10.80.30.00.0-0.10.00.60.3
Change in fecal boli incidents, locomotor task0.20.20.60.2-0.1-0.40.0-0.60.3-0.50.2-0.50.2-0.8
Time >=10cm from walls, locomotor time 13.53.65.81.8-2.1-2.01.5-2.40.1-2.11.9-2.02.2-1.8
Bouts of movement, locomotor time 10.40.41.4-1.00.70.81.20.60.50.4-0.30.20.10.4
Total resting periods, locomotor time 10.30.31.8-0.70.40.51.40.30.50.1-0.0-0.10.40.2
Rest time, locomotor task time 10.50.52.81.0-0.7-0.4-0.9-0.2-1.70.1-0.10.4-0.20.5
Distance moved, locomotor task time 10.50.61.20.1-0.4-0.60.6-0.81.1-0.90.7-1.00.7-1.0
Vertical activity count, locomotor time 10.20.20.70.9-0.6-0.6-0.4-0.4-0.7-0.30.2-0.10.2-0.2
Time >=10cm from walls, locomotor time 20.10.10.30.3-0.4-0.20.4-0.5-0.0-0.30.3-0.30.4-0.1
Bouts of movement, locomotor time 20.20.20.6-0.70.50.40.80.20.60.1-0.1-0.10.2-0.1
Total resting periods, locomotor time 20.10.10.6-0.40.20.10.8-0.10.6-0.20.2-0.30.4-0.3
Rest time, locomotor task time 20.81.02.61.6-1.3-1.2-0.9-0.8-1.6-0.60.5-0.30.3-0.5
Distance moved, locomotor task time 20.40.51.3-1.21.01.00.10.60.60.6-0.70.4-0.50.6
Vertical activity count, locomotor time 21.71.92.6-0.91.31.3-1.41.5-1.01.5-1.61.6-1.51.4
Light reinforcement 10.00.10.20.4-0.2-0.2-0.5-0.1-0.20.0-0.20.1-0.10.0
Light reinforcement 20.30.41.31.1-1.0-0.6-0.0-0.5-1.1-0.20.20.10.30.4
Bone: marrow area1.94.05.82.3-2.4-2.40.9-2.4-0.0-2.22.3-2.01.9-2.0
Bone: maximum diameter0.00.10.3-0.20.00.30.50.0-0.50.2-0.10.10.00.5
Bone: maximum force0.91.66.3-1.40.50.52.5-0.52.2-0.60.9-1.11.1-0.7
Bone: maximum moment0.81.45.3-1.20.50.42.3-0.52.1-0.60.8-1.01.0-0.7
Mean time between licks in bursts0.30.51.1-0.80.90.7-0.50.60.40.6-1.10.5-0.80.3
Mean num. licks in bursts0.10.20.30.5-0.4-0.5-0.0-0.3-0.1-0.40.5-0.40.3-0.6
Cd content in liver0.40.42.10.9-0.7-0.4-0.9-0.1-1.50.1-0.00.4-0.30.5
Co content in liver1.72.06.70.30.50.3-2.60.9-2.51.1-1.31.4-1.70.9
Cu content in liver0.00.10.2-0.40.20.20.40.0-0.2-0.1-0.0-0.30.2-0.2
Fe content in liver0.20.20.3-0.50.50.5-0.10.50.10.5-0.60.4-0.30.5
K content in liver0.90.93.2-0.70.1-0.01.8-0.51.3-0.70.9-1.10.9-1.0
Mg content in liver3.33.45.10.8-1.3-1.52.1-1.91.4-2.11.9-2.32.0-2.2
Mn content in liver0.91.04.0-1.50.91.01.70.42.00.2-0.1-0.10.30.2
Na content in liver1.01.01.7-1.11.11.3-0.21.0-0.11.1-1.31.0-0.91.2
Rb content in liver2.12.64.01.8-1.9-2.00.4-1.7-0.3-1.81.6-1.71.4-1.8
Se content in liver1.01.22.40.5-0.9-0.81.6-1.10.9-1.11.2-1.21.4-0.9
Sr content in liver2.42.23.9-2.01.81.9-0.11.5-0.01.6-1.41.4-1.31.5
Zn content in liver0.20.31.0-1.00.70.61.00.20.10.1-0.0-0.10.1-0.0
Bone: minimum diameter2.64.97.32.0-2.4-2.41.6-2.50.4-2.42.7-2.42.4-2.3
Time in familiar zone, hab. session 10.70.61.30.8-0.9-0.90.6-1.20.2-0.90.5-0.90.8-0.8
Time in novel zone, hab. session 10.60.61.7-0.10.50.4-1.30.9-0.80.7-0.70.8-1.00.6
Total zone transitions, hab. session 10.30.42.6-0.80.60.50.60.11.60.10.0-0.1-0.0-0.1
Total locomotion distance, hab. session 10.20.30.70.8-0.7-0.7-0.0-0.60.1-0.50.8-0.40.3-0.4
Locomotion velocity, hab. session 10.10.10.50.3-0.3-0.30.2-0.30.4-0.30.7-0.30.2-0.3
Time in familiar zone, hab. session 20.60.71.1-0.50.80.6-1.00.9-0.70.8-1.00.8-1.00.5
Time in novel zone, hab. session 20.90.91.30.4-0.8-0.71.1-0.91.0-1.01.1-1.11.1-0.9
Total zone transitions, hab. session 23.44.413.90.1-0.8-1.12.6-1.73.7-2.01.7-2.42.2-2.4
Total locomotion distance, hab. session 21.82.34.40.9-1.1-1.41.3-1.52.1-1.61.5-1.71.6-1.8
Locomotion velocity, hab. session 21.92.54.01.1-1.3-1.51.3-1.62.0-1.71.6-1.71.7-1.8
Novel to familiar place preference ratio0.50.52.4-0.4-0.2-0.01.5-0.51.0-0.50.6-0.70.9-0.3
Novelty place preference0.60.62.00.0-0.5-0.31.4-0.70.7-0.70.7-0.81.0-0.5
Time in novel zone, NPP test0.50.51.60.1-0.5-0.41.3-0.70.5-0.70.7-0.80.9-0.5
Total zone transitions, NPP test0.60.95.4-1.00.50.41.4-0.22.3-0.40.4-0.70.5-0.6
Total locomotion distance, NPP test0.20.31.00.2-0.3-0.40.4-0.51.0-0.50.7-0.60.4-0.6
Locomotion velocity, NPP test0.20.21.20.1-0.2-0.20.4-0.41.1-0.40.6-0.50.3-0.4
Intraocular pressure0.20.31.00.5-0.30.1-0.60.5-0.30.6-0.20.9-0.21.0
Delta distance traveled before/after self-admin0.00.00.1-0.00.10.1-0.20.1-0.10.1-0.30.2-0.20.2
Delta ambulatory time before/after self-admin0.10.10.2-0.20.20.2-0.40.2-0.20.3-0.50.3-0.40.2
Parametrial fat weight1.93.76.62.6-2.5-2.50.3-1.70.4-1.92.3-1.62.0-1.8
Pavlov. Cond. lever latency0.10.10.60.3-0.1-0.1-0.5-0.0-0.70.1-0.30.2-0.20.2
Pavlov. Cond. magazine entry latency1.21.63.40.5-0.9-0.91.5-1.21.8-1.31.2-1.31.5-1.2
Pavlov. Cond. change in total contacts0.60.61.30.4-0.7-0.51.2-0.81.0-0.70.7-0.71.0-0.3
Pavlov. Cond. index score0.10.10.6-0.0-0.2-0.00.5-0.10.8-0.10.1-0.20.30.0
Pavlov. Cond. latency score0.10.10.60.1-0.3-0.20.5-0.20.7-0.30.3-0.30.4-0.2
Pavlov. Cond. lever contacts0.00.00.30.0-0.0-0.00.10.00.5-0.10.1-0.10.1-0.1
Pavlov. Cond. magazine entry number0.10.10.60.2-0.1-0.3-0.5-0.1-0.7-0.10.1-0.1-0.2-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.40.2-0.00.1-0.50.2-0.60.40.00.5-0.30.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.8-0.2-0.00.10.7-0.10.9-0.10.1-0.20.3-0.0
Pavlov. Cond. response bias0.10.10.4-0.1-0.00.10.40.10.60.0-0.10.00.20.2
Pavlov. Cond. lever latency0.10.21.00.6-0.2-0.3-1.0-0.10.10.10.00.2-0.3-0.0
Pavlov. Cond. magazine entry latency0.91.14.3-1.50.80.72.1-0.21.7-0.30.0-0.80.6-0.5
Pavlov. Cond. change in total contacts0.71.05.9-0.8-0.00.22.4-0.61.0-0.70.5-1.01.2-0.4
Pavlov. Cond. index score0.50.74.0-1.20.50.62.0-0.20.7-0.20.1-0.60.6-0.2
Pavlov. Cond. latency score0.40.53.2-1.10.50.61.8-0.10.5-0.20.1-0.50.5-0.1
Pavlov. Cond. lever contacts0.20.20.5-0.70.50.60.60.4-0.50.3-0.50.2-0.10.5
Pavlov. Cond. magazine entry number1.41.77.12.1-1.1-1.1-2.70.1-2.00.20.10.7-0.70.3
Pavlov. Cond. intertrial magazine entries0.30.31.21.1-0.8-0.7-0.8-0.3-0.7-0.20.30.00.1-0.0
Pavlov. Cond. lever-magazine prob. diff.0.60.84.3-1.40.60.72.1-0.10.8-0.20.1-0.60.6-0.2
Pavlov. Cond. response bias0.30.52.3-1.10.60.71.50.10.6-0.0-0.3-0.30.30.1
Time in closed arm before self-admin0.20.30.50.4-0.5-0.40.7-0.70.5-0.50.5-0.50.6-0.3
Time in closed arm after self-admin0.00.00.10.00.0-0.10.10.10.2-0.10.2-0.10.0-0.2
Time in open arm before self-admin0.20.21.10.30.1-0.2-1.10.2-0.80.1-0.10.2-0.5-0.2
Time in open arm after self-admin0.30.30.90.00.20.2-0.90.4-0.90.5-0.40.6-0.60.5
Bone: periosteal estimation0.10.30.60.4-0.6-0.40.6-0.6-0.4-0.50.8-0.50.6-0.3
Bone: periosteal perimeter0.30.61.40.3-0.6-0.51.2-0.80.5-0.80.8-0.90.9-0.6
Bone: post-yield work8.812.018.81.6-2.8-2.74.3-3.83.4-3.73.7-3.94.0-3.4
Progressive ratio test 1 active lever presses1.31.33.11.7-1.6-1.5-0.1-1.3-0.4-1.11.1-0.90.8-0.9
Progressive ratio test 1 breakpoint0.91.02.41.6-1.4-1.3-0.3-1.1-0.5-0.90.9-0.60.6-0.7
Progressive ratio test 1 inactive lever presses0.80.91.71.3-1.2-1.20.1-1.2-0.4-1.01.0-0.80.8-0.9
Progressive ratio test 2 active lever presses2.22.45.02.2-2.1-1.90.1-1.9-0.7-1.51.7-1.11.3-1.1
Progressive ratio test 2 breakpoint1.71.95.32.3-2.0-1.8-0.6-1.6-1.3-1.11.3-0.70.8-0.7
Progressive ratio test 2 inactive lever presses5.05.812.63.5-3.3-3.1-0.0-2.9-1.2-2.32.4-1.81.9-1.8
Incentive Sensitization - Responses0.60.61.20.8-0.9-0.80.7-0.90.3-0.81.1-0.80.9-0.6
Incentive Sensitization - Breakpoint0.60.61.20.9-1.0-0.80.6-0.90.0-0.81.1-0.70.8-0.5
Sum of active levers in priming session hrs 5-62.92.85.3-1.71.62.1-0.51.6-0.31.9-2.01.8-1.42.3
Progressive ratio2.22.56.8-0.4-0.4-0.62.3-1.02.6-1.51.5-1.81.7-1.7
Food seeking constrained by brief footshock0.30.30.7-0.80.80.6-0.40.60.20.6-0.80.4-0.50.3
Seeking ratio, punishment vs. effort1.62.05.40.30.40.5-2.30.9-2.21.3-1.51.6-1.61.3
Retroperitoneal fat weight2.17.019.54.4-3.8-3.6-1.0-2.6-1.5-2.32.3-1.61.9-1.8
Reaction time number correct0.71.01.4-1.01.11.2-0.51.10.61.2-1.01.1-0.91.1
Reaction time mean minus median0.70.92.8-1.71.11.11.60.51.10.3-0.4-0.00.20.3
Reaction time mean minus median AUC0.91.22.9-1.71.41.50.51.20.71.0-0.90.8-0.50.9
Reaction time num false alarms0.81.12.7-0.40.90.7-1.61.1-0.61.1-1.11.2-1.40.9
Reaction time num false alarms AUC1.01.42.0-1.01.31.1-1.21.3-0.21.3-1.31.2-1.41.0
Reaction time trials correct on left0.71.01.4-1.01.11.2-0.51.10.61.2-1.01.1-0.91.1
Reaction time trials on left0.91.31.8-1.21.21.3-0.61.30.61.3-1.21.2-1.01.3
Reaction time mean0.00.10.30.0-0.1-0.00.3-0.2-0.5-0.1-0.1-0.10.20.0
Reaction time mean AUC0.10.10.20.2-0.3-0.20.5-0.4-0.4-0.30.1-0.30.4-0.1
Median of all reaction times0.10.20.50.5-0.5-0.40.2-0.5-0.7-0.40.2-0.30.3-0.2
Reaction time omissions0.71.02.6-1.61.41.30.41.00.70.9-1.00.6-0.50.7
Reaction time false alarm rate0.30.41.0-0.20.60.4-1.00.7-0.70.6-0.70.7-0.90.4
Reaction time premature initiation rate1.41.93.8-1.91.91.7-0.31.41.11.3-1.60.9-1.30.8
Reaction time premature initiations2.94.17.5-2.72.72.5-0.52.11.32.0-2.31.7-1.91.6
Std. dev. reaction times0.20.20.8-0.90.50.60.90.20.20.2-0.40.10.10.3
Reaction time trials completed0.91.31.8-1.21.21.3-0.61.30.61.3-1.21.2-1.01.3
Reaction time trials AUC0.71.01.2-1.01.11.1-0.61.10.61.1-1.01.1-0.91.1
Run reversals in cocaine runway, females0.60.61.5-0.2-0.0-0.40.8-0.41.1-0.80.6-1.00.6-1.2
Run reversals in cocaine runway, males3.02.94.1-0.71.21.4-2.01.7-1.91.8-1.72.0-1.91.9
Latency to leave start box in cocaine runway1.11.21.80.6-0.9-0.91.2-1.30.8-1.11.4-1.21.3-1.1
Latency to leave start box in cocaine runway, F0.50.50.80.4-0.6-0.60.8-0.80.7-0.80.9-0.80.9-0.8
Latency to leave start box in cocaine runway, M0.00.00.10.1-0.2-0.10.3-0.40.0-0.20.3-0.20.3-0.1
Std. dev. time between licks in bursts1.11.43.4-0.51.00.8-1.91.3-1.01.1-1.31.2-1.50.8
Total sessions with >9 infusions1.61.82.81.6-1.6-1.70.4-1.40.0-1.51.5-1.31.2-1.5
Short access day 1 total inactive lever presses1.92.15.22.3-2.0-1.9-0.4-1.5-0.6-1.31.5-1.01.0-1.1
Short access day 10 total inactive lever presses0.91.03.11.6-1.2-1.2-0.9-0.6-1.8-0.50.9-0.10.2-0.3
Short access day 1 total infusions4.44.76.82.5-2.5-2.60.8-2.40.2-2.42.5-2.22.1-2.2
Short access day 10 total infusions6.47.29.22.1-2.6-2.82.1-2.81.7-3.03.0-3.02.8-3.0
Short access total infusions3.13.54.61.8-1.9-2.11.1-2.01.0-2.12.1-2.01.8-2.2
Short access day 1 locomotion3.84.15.52.1-2.3-2.31.0-2.30.1-2.32.2-2.12.1-2.2
Short access day 10 total locomotion3.13.54.71.9-2.0-2.21.1-2.10.4-2.12.0-2.01.9-2.1
Short access total locomotion3.13.24.41.7-1.9-2.01.0-2.10.6-2.01.9-2.01.8-2.0
One hour access (0.3 mA shock)3.74.411.33.4-2.9-2.7-0.6-2.1-2.2-1.72.0-1.21.3-1.2
Compulsive drug intake2.42.44.6-2.12.11.8-0.51.80.71.5-1.71.2-1.61.0
One hour access (shock baseline)4.14.711.53.4-3.1-2.7-0.1-2.3-2.0-1.92.2-1.31.8-1.1
Social response proportion0.50.62.2-0.40.00.01.5-0.61.4-0.50.5-0.70.7-0.5
Social responses0.10.10.4-0.60.60.50.20.30.20.3-0.30.2-0.20.1
Social time0.20.30.6-0.80.80.7-0.00.50.10.5-0.50.4-0.50.4
Soleus weight1.23.513.43.0-2.1-1.9-2.4-0.9-3.7-0.50.80.2-0.2-0.1
Bone: stiffness1.21.96.6-0.90.00.02.6-1.02.2-1.01.2-1.41.4-1.0
Tibialis anterior weight5.318.245.2-6.76.05.80.74.71.64.1-3.63.1-3.13.4
Time to tail flick, vehicle, before self-admin0.30.31.1-0.30.0-0.10.8-0.31.1-0.40.5-0.60.6-0.6
Time to tail flick, vehicle, after self-admin0.40.51.9-0.90.60.30.90.21.4-0.20.7-0.50.3-0.7
Time to tail flick, test, before self-admin1.51.52.71.1-1.1-1.40.4-1.40.3-1.41.6-1.31.0-1.6
Time to tail flick, test, after self-admin0.00.00.1-0.10.10.2-0.10.1-0.40.2-0.30.2-0.10.2
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.50.30.10.7-0.10.5-0.20.5-0.30.2-0.4
Delta time to tail flick, test, before/after SA3.32.94.3-1.71.72.0-0.72.0-0.81.9-2.11.9-1.52.0
Tibia length0.72.03.6-1.81.51.90.21.4-0.61.5-1.51.3-1.11.8
Ambulatory time before self-admin0.20.20.9-0.3-0.10.10.9-0.30.8-0.10.3-0.20.50.1
Ambulatory time after self-admin0.91.01.60.8-1.1-0.91.0-1.30.4-1.01.1-1.01.2-0.7
Bone: tissue strength0.30.30.60.3-0.5-0.40.8-0.60.7-0.60.6-0.60.6-0.4
Total heroin consumption1.82.26.1-2.51.91.91.11.22.21.0-1.00.6-0.50.8
Bone: trabecular number2.23.57.80.2-1.0-1.12.8-1.42.4-1.91.9-2.12.3-1.9
Bone: trabecular spacing0.30.41.50.20.20.2-1.20.5-0.70.6-0.70.7-0.80.5
Bone: trabecular thickness1.92.33.01.3-1.5-1.61.5-1.60.6-1.71.4-1.71.7-1.7
Bone: trabecular tissue density1.01.46.11.8-1.2-0.9-1.5-0.5-2.50.00.30.5-0.40.5
Water consumed over 24 hours0.20.30.8-0.80.60.50.70.20.90.1-0.4-0.10.1-0.1
Number of responses in last shaping day0.30.31.10.8-0.4-0.4-1.0-0.3-1.1-0.00.20.2-0.3-0.0