Hub : Traits : Tibialis anterior weight : ← : →

chr2:225,664,331-228,461,478

Trait: Tibialis anterior weight

Best TWAS P=1.44e-10 · Best GWAS P=1.67e-10 conditioned to 4.63e-02

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dnajb14	gene expression	Dnajb14	0.28	52	0.27	7.2e-30	5.57	2.53e-08	0.35	FALSE
Adipose	Trmt10a	gene expression	Trmt10a	0.17	3694	0.12	3.4e-13	5.4	6.60e-08	0.17	FALSE
Adipose	Trmt10a	isoform ratio	XM_039102109.1	0.07	3694	0.03	1.2e-04	5.31	1.12e-07	0.05	FALSE
Adipose	Dnajb14	mRNA stability	Dnajb14	0.04	1	0.04	8.2e-05	5.22	1.80e-07	0.28	FALSE
Adipose	Rap1gds1	mRNA stability	Rap1gds1	0.12	107	0.1	1.3e-11	-5.86	4.59e-09	0.52	FALSE
BLA	Tspan5	gene expression	Tspan5	0.51	16	0.28	2.8e-15	5.37	7.86e-08	0.79	FALSE
Brain	Dnajb14	gene expression	Dnajb14	0.07	3439	0.04	1.7e-04	-5.72	1.08e-08	0.4	FALSE
Brain	Rap1gds1	gene expression	Rap1gds1	0.42	163	0.5	1.8e-52	-5.62	1.96e-08	0.81	FALSE
Brain	Tspan5	gene expression	Tspan5	0.7	478	0.48	1.7e-50	-5.32	1.06e-07	0.76	FALSE
IL	Tspan5	gene expression	Tspan5	0.52	1	0.2	1.7e-05	-6.01	1.80e-09	0.71	FALSE
LHb	Tspan5	alternative polyA	NM_001004090.2	0.32	1	0.16	1.5e-04	5.22	1.80e-07	0.05	FALSE
LHb	Tspan5	alternative polyA	XM_039102726.1	0.39	1	0.17	7.3e-05	-5.22	1.80e-07	0.05	FALSE
LHb	Stpg2	gene expression	Stpg2	0.2	2595	0.14	3.5e-04	5.89	3.77e-09	0.43	FALSE
LHb	Tspan5	gene expression	Tspan5	0.38	3	0.26	6.2e-07	5.48	4.20e-08	0.64	FALSE
LHb	Tspan5	isoform ratio	NM_001004090.2	0.69	1	0.24	2.0e-06	5.22	1.80e-07	0.06	FALSE
LHb	Tspan5	isoform ratio	XM_039102726.1	0.64	111	0.22	6.9e-06	-5.54	3.11e-08	0.33	FALSE
Liver	Dnajb14	gene expression	Dnajb14	0.1	144	0.09	1.5e-10	5.73	1.00e-08	0.01	FALSE
Liver	Mttp	gene expression	Mttp	0.31	26	0.25	6.2e-28	5.34	9.51e-08	0.4	FALSE
Liver	Rap1gds1	gene expression	Rap1gds1	0.25	12	0.24	7.3e-27	5.66	1.48e-08	0.34	FALSE
Liver	Trmt10a	gene expression	Trmt10a	0.08	3694	0.05	4.8e-06	5.61	2.02e-08	0.47	FALSE
Liver	Tspan5	gene expression	Tspan5	0.04	4	0.01	1.8e-02	6.11	9.83e-10	0.7	FALSE
Liver	Trmt10a	mRNA stability	Trmt10a	0.04	16	0.01	1.2e-02	-5.42	5.89e-08	0.52	FALSE
NAcc	Tspan5	alternative polyA	NM_001004090.2	0.1	1	0.11	3.2e-12	6.15	7.61e-10	0.97	FALSE
NAcc	Tspan5	alternative polyA	XM_039102726.1	0.1	1	0.1	1.9e-11	-6.09	1.12e-09	0.96	FALSE
NAcc	Rap1gds1	gene expression	Rap1gds1	0.07	6	0.09	3.1e-10	5.35	8.70e-08	0.62	FALSE
NAcc	RGD1309170	gene expression	RGD1309170	0.07	3682	0.04	4.5e-05	-5.33	9.56e-08	0.4	FALSE
NAcc	Trmt10a	gene expression	Trmt10a	0.19	3697	0.13	2.6e-14	5.18	2.23e-07	0.04	FALSE
NAcc	Tspan5	isoform ratio	NM_001004090.2	0.07	1	0.07	1.3e-08	6.09	1.12e-09	0.96	FALSE
NAcc	Tspan5	isoform ratio	XM_039102726.1	0.07	1	0.08	1.3e-09	-6.09	1.12e-09	0.96	FALSE
OFC	LOC102555623	alternative TSS	XR_005501334.1	0.24	3815	0.06	1.5e-02	-6.41	1.44e-10	0.51	TRUE
OFC	Rap1gds1	gene expression	Rap1gds1	0.19	1	0.12	7.9e-04	-5.89	3.89e-09	0.06	FALSE
OFC	Tspan5	gene expression	Tspan5	0.46	111	0.26	7.1e-07	-5.71	1.10e-08	0.76	FALSE
OFC	Rap1gds1	mRNA stability	Rap1gds1	0.17	1	0.08	5.8e-03	-5.47	4.47e-08	0.05	FALSE
PL	Tspan5	alternative polyA	NM_001004090.2	0.08	1	0.04	5.9e-05	5.6	2.20e-08	0.54	FALSE
PL	Tspan5	alternative polyA	XM_039102726.1	0.08	1	0.03	3.7e-04	-5.6	2.20e-08	0.39	FALSE
PL	Rap1gds1	gene expression	Rap1gds1	0.18	37	0.24	4.3e-26	-6.09	1.13e-09	0.71	FALSE
PL	Tspan5	gene expression	Tspan5	0.55	87	0.31	3.5e-35	-5.25	1.54e-07	0.79	FALSE
PL	Tspan5	isoform ratio	NM_001004090.2	0.1	1	0.07	6.9e-08	6.15	7.61e-10	0.97	FALSE
PL	Tspan5	isoform ratio	XM_039102726.1	0.1	1	0.08	6.5e-09	-6.15	7.61e-10	0.97	FALSE
PL	Rap1gds1	mRNA stability	Rap1gds1	0.07	18	0.06	1.4e-07	-6.03	1.68e-09	0.77	FALSE
pVTA	Tspan5	alternative polyA	NM_001004090.2	0.13	1	0.11	1.6e-05	5.72	1.08e-08	0.22	FALSE
pVTA	Tspan5	alternative polyA	XM_039102726.1	0.13	1	0.1	6.9e-05	-5.69	1.26e-08	0.19	FALSE
pVTA	Rap1gds1	gene expression	Rap1gds1	0.11	1	0.11	1.3e-05	-6.15	7.52e-10	0.79	FALSE
pVTA	Tspan5	isoform ratio	XM_039102726.1	0.13	10	0.07	4.8e-04	5.73	1.00e-08	0.79	FALSE
pVTA	LOC102547266	intron excision ratio	chr2_227257635_227259114	0.11	1	0.06	1.3e-03	-6.06	1.40e-09	0.4	FALSE