chr2:136,722,168-138,377,419

Trait: Tibialis anterior weight

Best TWAS P = 1.85e-08 · Best GWAS P= 2.43e-08 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ndufc1 alternative TSS NM_001399603.1 0.09 1 0.04 9.1e-06 -5.34 9.53e-08 0.66 FALSE
Adipose Ndufc1 alternative TSS XM_063282586.1 0.09 1 0.04 8.5e-06 5.34 9.53e-08 0.64 FALSE
Adipose Ndufc1 intron excision ratio chr2_137598220_137600156 0.07 1 0.06 2.1e-07 5.32 1.05e-07 0.76 FALSE
Adipose Ndufc1 intron excision ratio chr2_137599544_137600156 0.05 1 0.03 4.9e-04 -5.32 1.05e-07 0.11 FALSE
BLA Ndufc1 intron excision ratio chr2_137598220_137599505 0.14 2 0.11 3.3e-06 -5.43 5.68e-08 0.68 FALSE
BLA Ndufc1 intron excision ratio chr2_137598220_137600156 0.19 13 0.19 3.6e-10 5.34 9.22e-08 0.69 FALSE
Brain Rab33b gene expression Rab33b 0.08 14 0.11 8.0e-11 5.54 2.94e-08 0.69 FALSE
Brain Ndufc1 intron excision ratio chr2_137598220_137599505 0.08 1 0.08 2.9e-08 -5.58 2.43e-08 0.93 FALSE
IC Ndufc1 gene expression Ndufc1 0.32 1 0.27 1.5e-11 5.38 7.61e-08 0.81 FALSE
IL Ndufc1 isoform ratio XR_351688.4 0.2 1 0.11 1.6e-03 -5.24 1.61e-07 0.05 FALSE
LHb Noct gene expression Noct 0.17 1 0.09 3.9e-03 5.24 1.61e-07 0.06 FALSE
Liver LOC134485908 gene expression LOC134485908 0.03 1 0.01 4.9e-02 -5.49 3.98e-08 0.05 TRUE
NAcc Ndufc1 isoform ratio NM_001399603.1 0.23 48 0.26 5.3e-39 5.33 9.85e-08 0.65 FALSE
NAcc Ndufc1 intron excision ratio chr2_137598220_137599505 0.15 95 0.21 7.1e-32 -5.26 1.45e-07 0.68 TRUE
NAcc Ndufc1 intron excision ratio chr2_137598220_137600156 0.24 64 0.29 4.4e-45 5.34 9.16e-08 0.68 FALSE
NAcc Ndufc1 intron excision ratio chr2_137599544_137600156 0.13 32 0.17 3.0e-24 -5.26 1.42e-07 0.67 FALSE
OFC Ndufc1 intron excision ratio chr2_137599544_137600156 0.18 1981 0.06 1.6e-02 -5.21 1.85e-07 0.46 FALSE
PL Ndufc1 isoform ratio NM_001399603.1 0.21 27 0.28 1.7e-30 5.63 1.85e-08 0.69 TRUE
PL Ndufc1 isoform ratio XR_351688.4 0.18 10 0.24 2.0e-25 -5.51 3.49e-08 0.63 FALSE
PL Ndufc1 intron excision ratio chr2_137598220_137600156 0.33 17 0.38 4.5e-43 5.62 1.93e-08 0.72 FALSE
PL Ndufc1 intron excision ratio chr2_137599544_137600156 0.21 36 0.24 1.0e-25 -5.56 2.77e-08 0.72 FALSE
pVTA Ndufc1 gene expression Ndufc1 0.17 1 0.2 6.5e-16 5.41 6.47e-08 0.84 FALSE
pVTA Ndufc1 isoform ratio NM_001399603.1 0.21 18 0.27 1.5e-21 5.42 5.82e-08 0.66 TRUE
pVTA Ndufc1 isoform ratio XR_351688.4 0.16 1 0.21 3.5e-17 -5.33 9.62e-08 0.78 FALSE