Hub : Traits : TA weight in grams : ← →

chr2:122,912,439-125,075,599

Best TWAS P=2.660023e-08 · Best GWAS P=2.655895e-07 conditioned to 0.5381636

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	RGD1359508	alternative polyA	ENSRNOT00000058366	0.76	0.16	lasso	6	0.18	8.3e-20	4.7	-5.1	2.9e-07	-0.88	0.01	0.99	FALSE
2	Adipose	RGD1359508	alternative polyA	ENSRNOT00000114451	0.76	0.16	lasso	15	0.18	4.4e-20	4.7	5.1	3.2e-07	0.88	0.01	0.99	FALSE
3	Brain	Jade1	alternative polyA	ENSRNOT00000018872	0.20	0.06	enet	116	0.09	1.3e-08	4.6	5.4	6.2e-08	0.95	0.09	0.91	FALSE
4	Brain	Jade1	alternative polyA	ENSRNOT00000100298	0.20	0.06	enet	115	0.09	1.5e-08	4.6	-5.4	6.2e-08	-0.96	0.09	0.91	FALSE
5	Brain	Larp1b	alternative TSS	ENSRNOT00000044804	0.06	0.03	enet	31	0.03	3.7e-04	4.7	5.4	5.2e-08	0.85	0.31	0.61	FALSE
6	Brain	NEWGENE_1309446	gene expression	ENSRNOG00000010556	0.07	0.05	lasso	26	0.06	2.9e-06	5.1	5.3	1.3e-07	0.96	0.42	0.58	FALSE
7	Brain	Jade1	isoform ratio	ENSRNOT00000018872	0.08	0.00	enet	39	0.01	3.0e-02	4.7	5.2	1.7e-07	0.93	0.12	0.27	FALSE
8	Brain	Jade1	isoform ratio	ENSRNOT00000100298	0.22	0.07	enet	107	0.09	9.3e-09	4.6	-5.3	1.1e-07	-0.92	0.09	0.91	FALSE
9	Brain	Larp1b	isoform ratio	ENSRNOT00000044804	0.09	0.05	enet	36	0.05	1.2e-05	4.7	5.6	2.7e-08	0.87	0.32	0.68	TRUE
10	Liver	RGD1359508	alternative polyA	ENSRNOT00000114451	0.79	0.05	enet	12	0.07	1.9e-08	4.7	5.1	3.3e-07	0.89	0.01	0.99	FALSE
11	Liver	RGD1565989	gene expression	ENSRNOG00000013940	0.09	0.02	enet	37	0.02	1.1e-03	4.4	-5.3	1.2e-07	-0.93	0.36	0.56	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.