Body weight

Tags: Physiology · Weight

33 loci · 108 genes with independent associations · 1608 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	121178920	122571615	3	1	1.13e-08	1.43e-07	2.65e-01	Fam169b
2	chr1	203336735	204906888	2	1	1.43e-07	7.46e-07	2.03e-01	Rps6ka4
3	chr1	251447420	260518987	143	8	1.03e-40	4.13e-41	NaN	Ablim1 Gfra1 Gpam Grk5 Habp2 Nanos1 Prlhr
4	chr2	117887529	120172627	16	3	4.07e-08	3.10e-08	1.00e+00	Dcun1d1 Qrfpr Zfp267
5	chr2	120803918	122626616	2	1	3.89e-08	8.11e-11	4.18e-04	Fat4
6	chr2	123173249	125075599	3	1	4.46e-11	1.22e-06	9.84e-01	Jade1
7	chr2	127825544	129221363	1	1	1.98e-07	1.31e-08	2.16e-02	LOC120100812
8	chr2	225711801	227971227	2	2	1.29e-07	1.08e-10	2.77e-02	Lamtor3 LOC102547266
9	chr3	106069409	107821611	10	1	7.88e-08	1.32e-07	1.00e+00	Mapkbp1
10	chr3	114120424	117823761	80	1	3.45e-08	2.97e-08	1.00e+00	LOC103691888
11	chr3	126160536	128707024	30	4	6.71e-13	2.20e-12	NaN	Esf1 LOC102548513 Macrod2 Tasp1
12	chr3	129261795	133248752	86	7	8.02e-20	1.31e-17	1.00e+00	Bfsp1 Dtd1 Kif16b LOC102550304 LOC120101719 Slc24a3 Snrpb2
13	chr5	47704986	49968409	31	1	4.35e-09	2.56e-09	1.00e+00	RGD1359108
14	chr5	62111081	63507889	1	1	5.52e-08	5.25e-07	1.72e-15	Tex10
15	chr5	147480249	149238038	4	1	8.71e-08	8.05e-08	1.88e-01	Hmgcl
16	chr6	96850756	98633235	10	1	1.91e-09	2.33e-08	1.00e+00	Atp6v1d
17	chr7	26005811	30904027	68	5	5.54e-21	5.72e-25	1.00e+00	LOC102548848 LOC120093563 Ndufa12 Tmcc3
18	chr7	81443452	82946275	3	1	1.92e-10	8.88e-12	1.00e+00	Trps1
19	chr7	83305298	85354043	6	3	3.77e-10	2.35e-07	1.00e+00	Ext1 Med30
20	chr7	127695356	131793143	155	11	9.69e-11	2.69e-09	1.00e+00	Ccdc65 Faim2 Hdac7 Kcnh3 LOC102548155 Olr1877 Or8s8 Prkag1 Rapgef3 Tuba1b
21	chr8	75743509	77450698	2	1	1.74e-10	3.84e-08	1.32e-01	Hmgcll1
22	chr8	89750909	91141602	1	1	1.29e-07	6.99e-06	5.40e-01	Rasgrf1
23	chr8	94532832	97936197	29	6	1.98e-10	1.70e-08	1.00e+00	Atp1b3 LOC102551788 LOC102552777 Pls1 Rasa2 U2surp
24	chr8	108585012	112100485	164	5	1.23e-20	9.93e-10	1.00e+00	Arih2 Klhdc8b Mlh1 Ngp Setd2
25	chr10	81874092	84877260	65	6	1.02e-08	8.59e-08	1.00e+00	Cacnb1 Cisd3 Fbxl20 Neurod2 Rapgefl1 Smarce1
26	chr10	92588108	96071622	56	5	1.11e-10	1.51e-10	NaN	Abca9 Cep112 Map2k6
27	chr12	22091	6867512	226	8	4.11e-22	7.55e-22	NaN	Brca2 Insr LOC102548389 Pcp2 Pet100 Rxfp2 Stxbp2 Zfp958
28	chr12	36265873	37664019	1	1	4.33e-08	2.73e-09	1.90e-02	LOC108352453
29	chr18	25427994	26946372	31	1	5.85e-11	3.34e-10	1.00e+00	Cdc23
30	chr20	3201	847737	5	1	2.58e-08	4.32e-08	9.69e-54	Clic2
31	chr20	1930218	4798795	242	8	1.14e-10	3.20e-09	1.00e+00	Abcf1 Ddr1 LOC120093125 Prrc2a RT1-CE13 RT1-N2 RT1-S3 RT1-T24-3
32	chr20	5599216	8782719	128	9	2.16e-09	4.11e-09	1.00e+00	Ccdc167 Cpne5 Fkbp5 LOC120098864 Mtch1 Pi16 Rab44 Slc26a8
33	chr20	53722628	54429288	2	1	1.20e-14	1.38e-02	1.00e+00	LOC103694460

Pleiotropic Associations

Trait	Chi² ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	Corr	Corr P	Genes
BMI with tail	11	135	90	83.3	1	0.00e+00	Abca6 Abca9 Abhd18 Ablim1 Acsl5 Adrb1 Afap1l2 Amz2 Ankrd50 Anxa5 Apc Apoh Arsg Atp11b Atp1b3 Atrnl1 Axin2 Bbs7 Brd8 Cacul1 Casp7 Ccdc186 Cd99 Cdc23 Cep112 Ces2c Chst2 Dclre1a Dcun1d1 Dennd10 Dstn Dtd1 Dzank1 Ehd4 Emx2os Eno4 Epb41l4a Ext1 Fam13b Fam204a Fam20a Fat4 Fermt3 Fhip2a Flrt3 Gfra1 Gk5 Gpam Grk5 Gucy2g Habp2 Hdac7 Hmgcll1 Hspa12a Jade1 Kif16b Kif20a Klhdc8b Larp1b LOC100912202 LOC102547573 LOC102548155 LOC102548513 LOC102548590 LOC102550112 LOC102550304 LOC102550729 LOC102551125 LOC102552777 LOC103694460 LOC103694952 LOC120095201 LOC120098271 LOC120100065 LOC120100068 LOC120101717 LOC120101719 Macrod2 Map2k6 Mapkbp1 Mccc1 Med30 Nanos1 Ndufaf5 Nhlrc2 Nme5 Nrap Otor PCOLCE2 Pcsk2 Pfkm Pkd2l2 Pla2g4b Plekhs1 Pls1 Pnlip Polr3f Prdx3 Prkca Prlhr Qrfpr Rab11fip2 Rasa2 Rbbp9 Reep5 RGD1565459 Rgs9 Rnf7 Rpap3 Rps6ka4 Rrbp1 Scg3 Sec23b Sfxn4 Slc16a6 Smim26 Snrpb2 Sptbn5 Srp19 Tasp1 Tcf7l2 Tectb Tfdp2 Tmcc3 Tmem106c Trpc1 Trps1 Trub1 U2surp Vti1a Wipi1 Zdhhc6 Zfp133 Zfp267 Zfp950
BMI without tail	15.75	32	16	14.8	1	4.63e-170	Cacul1 Ces2c Dennd10 Dstn Emx2os Epb41l4a Fam204a Grk5 Hspa12a Kif16b Klhdc8b LOC102548590 LOC102550729 LOC120100068 LOC120101717 LOC120101719 Mir331 Nanos1 Otor Pcsk2 Prdx3 Prlhr Rab11fip2 Rnf7 Rrbp1 Sec23b Sfxn4 Snrpb2 Tfdp2 Trpc1 Trps1 Zfp950
Epididymis fat weight	16.95	77	48	44.4	0.99	0.00e+00	Abca6 Abca9 Ablim1 Acsl5 Add3 Adrb1 Afap1l2 Amz2 Apoh Arsg Atrnl1 Axin2 Cacul1 Casp7 Ccdc186 Cep112 Ces2c Dclre1a Dennd10 Dstn Emx2os Eno4 Fam204a Fam20a Fhip2a Flrt3 Gfra1 Gpam Grk5 Gucy2g Habp2 Hspa12a Ism1 Kif16b LOC100912202 LOC102547573 LOC102548513 LOC102550112 LOC102550729 LOC102551125 LOC120095201 LOC120100064 LOC120100065 LOC120100068 LOC120101717 LOC120101719 Macrod2 Mxi1 Nanos1 Nhlrc2 Nrap Otor Pcsk2 Plekhs1 Pnlip Prdx3 Prkar1a Prlhr Rab11fip2 Rbbp9 RGD1565459 Rgs9 Rrbp1 Sec23b Sfxn4 Shoc2 Slc16a6 Snrpb2 Sptlc3 Tasp1 Tcf7l2 Tectb Trub1 Vti1a Wipi1 Zdhhc6 Zfp950
Heart weight	17.24	1	0	0	0	1.00e+00	Klhdc8b
Left kidney weight	10.37	73	43	39.8	0.98	0.00e+00	Acsl5 Arhgef18 Asap3 Brca2 Cacul1 Camsap3 Casp7 Cd209a Cd99 Cers4 Ces2c Dennd10 Elavl1 Emx2os Fam204a Fry Gpam Grk5 Gucy2g Hmgb1 Hmgcl Hnrnpr Hsph1 Insr Katnal1 Kl Klhdc8b Lnc001 LOC102546827 LOC102548389 LOC102549089 LOC102549494 LOC102550729 LOC102552452 LOC102553253 LOC103690858 LOC103694460 LOC108352411 LOC120095826 LOC120095830 LOC120095870 LOC120095871 LOC120095873 LOC120100064 LOC120100068 Map2k7 Mcemp1 Mcoln1 Medag N4bp2l1 N4bp2l2 Nanos1 Pcp2 Pet100 Pex11g Pi16 Pnpla6 Prdx3 Prlhr Rab11fip2 Rxfp2 Sfxn4 Snapc2 Stard13 Stxbp2 Tcf7l2 Timm44 Trappc5 Vti1a Wdr95 Xab2 Zfp950 Zfp958
Right kidney weight	9.33	80	43	39.8	0.99	0.00e+00	Ablim1 Acsl5 Adrb1 Arhgef18 Atrnl1 B3glct Brca2 Cacul1 Camsap3 Casp7 Cd209a Cers4 Ces2c Dennd10 Elavl1 Emx2os Fam204a Fhip2a Fry Gpam Grk5 Gucy2g Habp2 Hmgb1 Hsph1 Insr Katnal1 Kl Klhdc8b Lnc001 LOC102546827 LOC102547573 LOC102548389 LOC102549089 LOC102549494 LOC102550729 LOC102552777 LOC102553253 LOC102554603 LOC103690858 LOC103694460 LOC108352411 LOC120095826 LOC120095830 LOC120095870 LOC120095871 LOC120095873 LOC120095879 LOC120100064 LOC120100065 LOC120100068 Map2k7 Mcemp1 Mcoln1 Medag N4bp2l1 N4bp2l2 Nanos1 Nhlrc2 Nrap Pcp2 Pet100 Pex11g Plekhs1 Prdx3 Prlhr Rab11fip2 Rxfp2 Sfxn4 Snapc2 Stard13 Stxbp2 Tcf7l2 Trappc5 Uspl1 Vti1a Wdr95 Xab2 Zfp950 Zfp958
Tail length	8.22	125	47	43.5	0.99	0.00e+00	Abcf1 Als2cl Amdhd1 Arhgef18 Arih2 Atrip Bag6 Brca2 Camp Camsap3 Ccdc12 Ccdc38 Ccdc51 Cchcr1 Cd209a Cdc25a Cdk17 Cep83 Cers4 Cspg5 Dclk3 Ddr1 Dhx16 Elavl1 Elk3 Elp6 Epm2aip1 Fam240a Fgd6 Fry Gnl1 Gtf2h4 Insr Kif9 Kl Klhdc8b Klhl18 Lnc001 LOC102548389 LOC102548950 LOC102549089 LOC102552452 LOC102552504 LOC102553539 LOC102554603 LOC102556485 LOC103690858 LOC108351781 LOC120093125 LOC120093556 LOC120093559 LOC120093563 LOC120095826 LOC120095871 LOC120095873 LOC120098967 Lrrc2 Lrrfip2 Lta4h Map2k7 Map4 Mcoln1 Metap2 Mir331 Mlh1 Mrpl42 Mrps18b Myl3 N4bp2l1 N4bp2l2 Nbeal2 Nckipsd Ndufa12 Ngp Nme6 Nr2c1 Nradd Nrm Ntn4 Nudt4 Pcp2 Pet100 Pex11g Pfkfb4 Plxnb1 Plxnc1 Pnpla6 Prr3 Prss50 Pth1r Ptpn23 RT1-CE1 RT1-CE10 RT1-CE11 RT1-CE14 RT1-CE15 RT1-N2 RT1-N3 RT1-S3 RT1-T18 RT1-T24-1 RT1-T24-2 RT1-T24-4 Rtp3 Scap Setd2 Shisa5 Smarcc1 Snapc2 Snrpf Socs2 Stard13 Stxbp2 Tcf19 Timm44 Tmcc3 Tmie Trank1 Trappc5 Trex1 Ube2n Vars2 Vezt Xab2 Zfp958
Length with tail	10.54	177	131	121.3	0.99	0.00e+00	Abcf1 Als2cl Amdhd1 Arhgef18 Arih2 Arl5c Atat1 Atp6v1d Atrip B3glct Bag6 Brca2 Cacnb1 Camp Camsap3 Cb707485 Ccdc12 Ccdc38 Ccdc51 Cchcr1 Cd209a Cdc25a Cdk17 Cdsn Cep83 Cep83os Cers4 Cisd3 Cspg5 Ctxn1 Cwc25 Dclk3 Ddr1 Dhx16 Ebf4 Elavl1 Elk3 Elp6 Epm2aip1 Epop Fam240a Fbxl20 Fgd6 Fkbp5 Flot1 Fry G4 Gnl1 Gtf2h4 Hmgb1 Hsph1 Insr Katnal1 Kif16b Kif9 Kl Klhdc8b Klhl18 Lnc001 LOC102546827 LOC102548260 LOC102548389 LOC102548848 LOC102548950 LOC102549089 LOC102549494 LOC102552452 LOC102552504 LOC102553244 LOC102553253 LOC102553539 LOC102554603 LOC102556485 LOC103690858 LOC108349027 LOC108351781 LOC108352411 LOC120093125 LOC120093556 LOC120093559 LOC120093563 LOC120095826 LOC120095830 LOC120095870 LOC120095871 LOC120095873 LOC120098966 LOC120098967 Lrrc2 Lrrc8e Lrrfip2 Lta4h Map2k7 Map4 Mcemp1 Mcoln1 Medag Metap2 Mir331 Mlh1 Mllt6 Mrpl42 Mrps18b Myl3 N4bp2l1 N4bp2l2 Nbeal2 Nckipsd Ndufa12 Ngp Nme6 Nr2c1 Nradd Nrm Ntn4 Nudt4 Otor Pced1a Pcp2 Pds5b Pdyn Pet100 Pex11g Pfkfb4 Plxnb1 Plxnc1 Pnpla6 Prr3 Prss50 Pth1r Ptpn23 Ptpra Retn Rpl19 RT1-CE10 RT1-CE11 RT1-CE4 RT1-N2 RT1-N3 RT1-O1 RT1-S2 RT1-S3 RT1-T18 RT1-T24-1 RT1-T24-2 RT1-T24-3 RT1-T24-4 Rtp3 Rxfp2 Scap Setd2 Shisa5 Slc26a8 Smarcc1 Snapc2 Snrpb Snrpb2 Snrpf Socs2 Srcin1 Stac2 Stard13 Stxbp2 Tcf19 Timm44 Tma7 Tmcc3 Tmie Trank1 Trappc5 Trex1 Ube2n Vars2 Vezt Wdr95 Xab2 Zfp958
Length without tail	11.8	73	34	31.5	0.99	0.00e+00	Alox5ap Arhgef18 Asb8 Brca2 Cacul1 Camsap3 Cd209a Cers4 Dclk3 Ddx23 Elavl1 Fgd6 Fry Grk5 Hdac7 Hmgb1 Hsph1 Insr Kansl2 Katnal1 Kl Lnc001 LOC102546827 LOC102548155 LOC102548389 LOC102549089 LOC102549494 LOC102552452 LOC102553253 LOC102553539 LOC103690858 LOC108351548 LOC108352411 LOC120093563 LOC120095826 LOC120095830 LOC120095871 LOC120095873 LOC120095879 Lrrc8e Lta4h Map2k7 Mcemp1 Mcoln1 Medag Mir331 Mrpl42 N4bp2l1 N4bp2l2 Ndufa12 Nr2c1 Or8s2 Pcp2 Pet100 Pex11g Pfkm Plxnc1 Prlhr Rapgef3 Rpap3 Rxfp2 Slc48a1 Snapc2 Stard13 Stxbp2 Timm44 Tmem106c Trappc5 Uspl1 Vezt Wdr95 Xab2 Zfp958
Liver weight, left	13.45	1	0	0	0	1.00e+00	Klhdc8b
Liver weight, right	15.14	12	6	5.6	0.98	7.81e-21	Cacul1 Cd99 Dennd10 Fam204a Grk5 LOC103694460 Nanos1 Plekhs1 Prlhr Rab11fip2 Sfxn4 Vti1a
Parametrial fat weight	16.19	55	31	28.7	0.99	0.00e+00	Ablim1 Acsl5 Afap1l2 Atrnl1 Bfsp1 Cacul1 Casp7 Ccdc186 Ces2c Dclre1a Dennd10 Dstn Dtd1 Dzank1 Emx2os Eno4 Fam204a Fhip2a Gfra1 Gpam Grk5 Gucy2g Habp2 Hspa12a Kif16b LOC102547573 LOC102550304 LOC102550729 LOC102551125 LOC120100065 LOC120100068 LOC120101717 LOC120101719 Nanos1 Nhlrc2 Nrap Otor Pcsk2 Plekhs1 Pnlip Polr3f Prdx3 Prlhr Rab11fip2 Rbbp9 Rrbp1 Sec23b Sfxn4 Smim26 Snrpb2 Tcf7l2 Trub1 Zdhhc6 Zfp133 Zfp950
Retroperitoneal fat weight	17.46	85	70	64.8	1	0.00e+00	Ablim1 Acsl5 Add3 Adrb1 Afap1l2 Apoh Arsg Atrnl1 Axin2 Bfsp1 Cacul1 Casp7 Ccdc186 Cd99 Cep112 Ces2c Dclre1a Dennd10 Dstn Dtd1 Dzank1 Emx2os Eno4 Esf1 Fam204a Fhip2a Flrt3 Gfra1 Gpam Grk5 Gucy2g Habp2 Hspa12a Ism1 Kat14 Kif16b Klhdc8b LOC102547573 LOC102548513 LOC102550112 LOC102550304 LOC102550729 LOC102551125 LOC103694460 LOC120095201 LOC120100064 LOC120100065 LOC120100068 LOC120101717 LOC120101719 Macrod2 Mxi1 Nanos1 Ndufaf5 Nhlrc2 Nrap Otor Pcsk2 Pdcd4 Plekhs1 Pnlip Polr3f Prdx3 Prkca Prlhr Rab11fip2 Rbbp9 Rgs9 Rrbp1 Sec23b Sfxn4 Shoc2 Smim26 Snrpb2 Sptbn5 Sptlc3 Tasp1 Tcf7l2 Tectb Tex10 Trub1 Vti1a Zdhhc6 Zfp133 Zfp950
Intraocular pressure	19.47	2	1	0.9	0	1.00e+00	LOC102548155 LOC103694460
Extensor digitorum longus weight	6.19	126	47	43.5	0.98	0.00e+00	Adcy6 Ankrd50 Anxa5 Arf3 Arhgef18 Arl5c Asb8 Atp11b Bbs7 Brca2 C7h12orf54 Cacnb1 Cacnb3 Camsap3 Ccdc65 Ccnt1 Cd209a Cdk12 Cers4 Cfap206 Cisd3 Col2a1 Ctxn1 Cwc25 Dcun1d1 Ddx23 Dnajc22 Elavl1 Endou Epop Fat4 Fbxl20 Fermt3 Fkbp11 Fry Grb7 Hdac7 Igfbp4 Insr Jade1 Kansl2 Kcnh3 Kl Kmt2d Lamtor3 Larp1b Lasp1 Lmbr1l LOC102547266 LOC102548155 LOC102548389 LOC102549089 LOC102549494 LOC102552452 LOC102556302 LOC102557269 LOC103692978 LOC103694460 LOC108351548 LOC108352129 LOC120093728 LOC120093732 LOC120093830 LOC120095826 LOC120095871 LOC120095873 Lrrc8e Map2k7 Mccc1 Mcemp1 Mcoln1 Med1 Med30 Mllt6 Msl1 N4bp2l1 N4bp2l2 Neurod2 Olr1877 Or8s2 Orc3 Ormdl3 Pced1b Pcgf2 Pcp2 Pet100 Pex11g Pfkm Ppp1r1b Prkag1 Qrfpr Rapgef3 Rapgefl1 Rars2 RGD1359108 Rhebl1 Rnd1 Rpap3 Rpl19 Rpl23 Rps6ka4 Rxfp2 Senp1 Slc35a1 Slc48a1 Smarce1 Snapc2 Spmip11 Srcin1 Stac2 Stard13 Stard3 Stxbp2 Timm44 Tmem106c Trappc5 Tuba1a Tuba1b Tuba1c Vdr Wipf2 Xab2 Zfp267 Zfp641 Zfp958 Zpbp2
Soleus weight	7.07	9	0	0	0.99	4.41e-13	Ablim1 Atrnl1 Gpam Grk5 Klhdc8b LOC120100068 Tectb Trub1 Vti1a
Tibialis anterior weight	7.55	65	40	37	0.98	0.00e+00	Ankrd50 Anxa5 Arg2 Arhgef18 Atp11b Atp6v1d Bbs7 Brca2 Camsap3 Cd209a Cers4 Cfap206 Cnr1 Ctxn1 Dcun1d1 Elavl1 Fat4 Fermt3 Fry Insr Jade1 Kl Larp1b LOC102547266 LOC102548389 LOC102549089 LOC102549494 LOC102552452 LOC102557269 LOC103690858 LOC103694460 LOC120095826 LOC120095871 LOC120095873 LOC120102853 Lrrc8e Map2k7 Mccc1 Mcemp1 Mcoln1 Med30 N4bp2l1 N4bp2l2 Orc3 Pals1 Pcp2 Pet100 Pex11g Pigh Pnpla6 Qrfpr Rars2 Retn RGD1359108 Rps6ka4 Rxfp2 Slc35a1 Snapc2 Stard13 Stxbp2 Timm44 Trappc5 Xab2 Zfp267 Zfp958
Tibia length	8.03	123	21	19.4	0.99	0.00e+00	Adcy6 Als2cl Amdhd1 Arf3 Arih2 Asb8 Atrip C7h12orf54 Cacnb3 Camp Ccdc12 Ccdc38 Ccdc51 Ccdc65 Ccnt1 Cdc25a Cep83 Cep83os Col2a1 Cspg5 Dclk3 Ddx23 Dhh Dnajc22 Elk3 Elp6 Epm2aip1 Esf1 Fgd6 Fkbp11 Flrt3 Insr Kansl2 Kif16b Kif9 Klhdc8b Klhl18 Kmt2d Lmbr1l LOC102546778 LOC102548155 LOC102548513 LOC102548848 LOC102548950 LOC102552504 LOC102553539 LOC102556302 LOC102556485 LOC103692978 LOC108351781 LOC120093556 LOC120093559 LOC120093563 LOC120093732 LOC120093830 LOC120095870 LOC120101717 Lrrc2 Lrrfip2 Lta4h Macrod2 Map2k7 Map4 Mcoln1 Mir331 Mlh1 Myl3 N4bp2l1 N4bp2l2 Nbeal2 Nckipsd Ndufa12 Ndufaf5 Ngp Nme6 Nr2c1 Nradd Ntn4 Olr1877 Or8s2 Otor Pcp2 Pet100 Pfkfb4 Pfkm Plxnb1 Plxnc1 Prkag1 Prph Prss50 Pth1r Ptpn23 Rapgef3 Rhebl1 Rnd1 Rpap3 Rtp3 Scap Senp1 Setd2 Shisa5 Slc48a1 Smarcc1 Snapc2 Snrpb2 Snrpf Socs2 Spats2 Spmip11 Sptlc3 Stxbp2 Tasp1 Tmcc3 Tmem106c Trank1 Trex1 Tuba1a Tuba1b Tuba1c Ube2n Vezt Wnt1 Zfp641
Number of licking bursts	24.53	1	1	0.9	0	1.00e+00	Klhdc8b
Patch foraging indifference point 0 sec	12.96	1	0	0	0	1.00e+00	LOC103694460
Indifference point function ln k	36.38	1	1	0.9	0	1.00e+00	Klhdc8b
Indifference point function log k	36.38	1	1	0.9	0	1.00e+00	Klhdc8b
Patch foraging total patch changes 0 sec	12.64	1	0	0	0	1.00e+00	LOC103694460
Locomotor activity	57.78	1	1	0.9	0	1.00e+00	Klhdc8b
Locomotor testing distance	64.52	1	1	0.9	0	1.00e+00	Klhdc8b
Reaction time number correct	18.64	1	1	0.9	0	1.00e+00	Klhdc8b
Reaction time trials correct on left	18.64	1	1	0.9	0	1.00e+00	Klhdc8b
Reaction time trials on left	19.51	1	1	0.9	0	1.00e+00	Klhdc8b
Reaction time omissions	23.75	1	1	0.9	0	1.00e+00	Klhdc8b
Reaction time false alarm rate	20.24	1	1	0.9	0	1.00e+00	Klhdc8b
Std. dev. reaction times	14.2	1	0	0	0	1.00e+00	Jade1
Reaction time trials completed	19.51	1	1	0.9	0	1.00e+00	Klhdc8b
Reaction time trials AUC	20.65	1	1	0.9	0	1.00e+00	Klhdc8b
Conditioned locomotion	28.4	1	1	0.9	0	1.00e+00	Klhdc8b
Cocaine response before conditioning	38.66	1	1	0.9	0	1.00e+00	Klhdc8b
Condit. Reinf. active responses	14.63	2	0	0	0	1.00e+00	Fam13b Reep5
Condit. Reinf. lever reinforcers received	13.94	2	0	0	0	1.00e+00	Fam13b Reep5
Pavlov. Cond. index score	15.43	1	0	0	0	1.00e+00	LOC103694460
Pavlov. Cond. magazine entry number	25.13	2	1	0.9	0	1.00e+00	Klhdc8b LOC103694460
Conditioned reinforcement - inactives	16.77	1	0	0	0	1.00e+00	Klhdc8b
Intermitt. access day 15 inactive lever presses	30.78	1	1	0.9	0	1.00e+00	Klhdc8b
Intermittent access terminal intake (last 3 days)	24.03	1	0	0	0	1.00e+00	Klhdc8b
Short access day 10 total inactive lever presses	101.65	1	1	0.9	0	1.00e+00	Klhdc8b
Locomotion distance, session 1	23.98	1	1	0.9	0	1.00e+00	Klhdc8b
Locomotion distance, session 2	33.15	1	1	0.9	0	1.00e+00	Klhdc8b
Locomotion velocity, session 3	17.14	1	0	0	0	1.00e+00	Klhdc8b
Locomotion distance, session 8	52.78	1	1	0.9	0	1.00e+00	Klhdc8b
Degree of sensitization distance	24.75	1	0	0	0	1.00e+00	Klhdc8b
Condit. Reinf. active minus inactive responses	35.59	1	1	0.9	0	1.00e+00	Klhdc8b
Condit. Reinf. active-inactive response ratio	25.6	1	1	0.9	0	1.00e+00	Klhdc8b
Condit. Reinf. active responses	18.23	1	0	0	0	1.00e+00	Klhdc8b
Incentive salience index mean	26.23	1	1	0.9	0	1.00e+00	Klhdc8b
Time in familiar zone, hab. session 1	63.49	1	1	0.9	0	1.00e+00	Klhdc8b
Total zone transitions, hab. session 1	37.38	1	1	0.9	0	1.00e+00	Klhdc8b
Time in familiar zone, hab. session 2	27.1	1	1	0.9	0	1.00e+00	Klhdc8b
Total zone transitions, hab. session 2	69.58	1	1	0.9	0	1.00e+00	Klhdc8b
Total locomotion distance, hab. session 2	19.2	1	0	0	0	1.00e+00	Klhdc8b
Locomotion velocity, hab. session 2	21.15	1	1	0.9	0	1.00e+00	Klhdc8b
Novel to familiar place preference ratio	22.33	1	0	0	0	1.00e+00	Klhdc8b
Novelty place preference	20.99	1	0	0	0	1.00e+00	Klhdc8b
Total zone transitions, NPP test	59.86	2	1	0.9	0	1.00e+00	Klhdc8b Trpc1
Total locomotion distance, NPP test	47.64	1	1	0.9	0	1.00e+00	Klhdc8b
Locomotion velocity, NPP test	51.12	1	1	0.9	0	1.00e+00	Klhdc8b
Pavlov. Cond. change in total contacts	69.48	1	1	0.9	0	1.00e+00	Klhdc8b
Pavlov. Cond. magazine entry number	15.14	1	0	0	0	1.00e+00	Fbxl20
Bone: apparent density	12.38	17	0	0	0.99	3.78e-52	Adcy6 Ddx23 Fry Hmgb1 Hsph1 Kansl2 LOC102546827 LOC102548389 LOC102549494 LOC102553253 LOC120095871 LOC120095873 Mcemp1 Rnd1 Rxfp2 Trappc5 Zfp958
Bone surface	11.81	55	0	0	0.99	1.76e-227	Adcy6 Arf3 Asb8 C7h12orf54 Cacnb3 Ccdc65 Ccnt1 Col2a1 Ddx23 Dhh Dnajc22 Faim2 Fkbp11 Fry Hdac7 Hsph1 Kansl2 Kcnh3 Kmt2d Lmbr1l LOC100362820 LOC102546778 LOC102546827 LOC102548155 LOC102548389 LOC102549494 LOC102556302 LOC103692978 LOC108351548 LOC120093732 LOC120093830 LOC120095871 LOC120095873 Olr1877 Or8s2 Pfkm Prkag1 Prph Rapgef3 Rhebl1 Rnd1 Rxfp2 Senp1 Slc48a1 Snapc2 Spats2 Spmip11 Tmem106c Trappc5 Tuba1a Tuba1b Tuba1c Wnt1 Zfp641 Zfp958
Bone volume	12.31	11	0	0	1	2.90e-42	Fry Hsph1 Lnc001 LOC102546827 LOC102548389 LOC102549494 LOC120095871 LOC120095873 Mcemp1 Rxfp2 Zfp958
Bone: connectivity density	13.37	12	1	0.9	1	4.35e-43	Fry Hsph1 LOC102546827 LOC102548389 LOC102549494 LOC120095871 LOC120095873 Mcemp1 Rxfp2 Snapc2 Trappc5 Zfp958
Bone: cortical area	13.91	23	0	0	0.98	5.88e-50	Ablim1 Acsl5 Afap1l2 Cacul1 Casp7 Ces2c Dclre1a Dennd10 Emx2os Fam204a Fhip2a Grk5 Habp2 LOC102547573 LOC102550729 LOC120100065 LOC120100068 Nhlrc2 Plekhs1 Prlhr Rab11fip2 Sfxn4 Zfp950
Bone: cortical thickness	16.47	10	5	4.6	0.94	5.17e-14	Emx2os Esf1 Ism1 LOC120100068 Macrod2 Ndufaf5 Prlhr Rab11fip2 Sptlc3 Tasp1
Bone: endosteal estimation	8.88	2	0	0	0	1.00e+00	LOC102546778 Slc26a8
Bone: endosteal perimeter	18.12	2	1	0.9	0	1.00e+00	Cd99 LOC103694460
Bone: final force	12.04	5	0	0	0.93	2.19e-02	Faim2 LOC100362820 LOC102546778 Spats2 Zfp950
Bone: final moment	12.41	13	0	0	0.92	5.81e-08	Adcy6 Cacul1 Ddx23 Faim2 Grk5 Kansl2 Kcnh3 LOC100362820 LOC102546778 Prlhr Sfxn4 Spats2 Zfp950
Bone: marrow area	8.76	2	0	0	0	1.00e+00	LOC102546778 Slc26a8
Bone: maximum diameter	11.7	14	1	0.9	0.99	2.80e-26	Ablim1 Acsl5 Afap1l2 Casp7 Ccdc186 Cd99 Dclre1a Fhip2a Habp2 LOC102547573 LOC103694460 LOC120100065 Nhlrc2 Plekhs1
Bone: maximum force	13.37	51	5	4.6	0.99	0.00e+00	Adcy6 Arf3 Asb8 C7h12orf54 Cacnb3 Cacul1 Ccdc65 Ccnt1 Col2a1 Ddx23 Dhh Dnajc22 Endou Faim2 Fkbp11 Hdac7 Kansl2 Kcnh3 Kmt2d Lmbr1l LOC100362820 LOC102546778 LOC102548155 LOC102556302 LOC103692978 LOC108351548 LOC120093728 LOC120093732 LOC120093830 Olr1877 Or8s2 Pced1b Pfkm Prkag1 Prlhr Prph Rapgef3 Rhebl1 Rnd1 Rpap3 Senp1 Slc48a1 Spats2 Spmip11 Tmem106c Tuba1a Tuba1b Tuba1c Vdr Wnt1 Zfp641
Bone: maximum moment	13.37	54	7	6.5	0.98	2.27e-278	Adcy6 Arf3 Asb8 C7h12orf54 Cacnb3 Cacul1 Ccdc65 Ccnt1 Col2a1 Ddx23 Dhh Dnajc22 Endou Faim2 Fkbp11 Grk5 Hdac7 Kansl2 Kcnh3 Kmt2d Lmbr1l LOC100362820 LOC102546778 LOC102548155 LOC102556302 LOC103692978 LOC108351548 LOC120093728 LOC120093732 LOC120093830 Olr1877 Or8s2 Pced1b Pfkm Prkag1 Prlhr Prph Rapgef3 Rhebl1 Rnd1 Rpap3 Senp1 Sfxn4 Slc48a1 Spats2 Spmip11 Tmem106c Tuba1a Tuba1b Tuba1c Vdr Wnt1 Zfp641 Zfp950
Bone: minimum diameter	10.22	1	0	0	0	1.00e+00	LOC102546778
Bone: periosteal estimation	12.03	59	7	6.5	0.97	1.04e-239	Acsl5 Adcy6 Arf3 Asb8 C7h12orf54 Cacnb3 Cacul1 Ccdc65 Ccnt1 Col2a1 Ddx23 Dennd10 Dhh Dnajc22 Endou Faim2 Fam204a Fkbp11 Grk5 Hdac7 Kansl2 Kcnh3 Kmt2d Lmbr1l LOC100362820 LOC102546778 LOC102548155 LOC102556302 LOC103692978 LOC108351548 LOC120093728 LOC120093732 LOC120093830 Olr1877 Or8s2 Pced1b Pfkm Plekhs1 Prkag1 Prlhr Prph Rab11fip2 Rapgef3 Rhebl1 Rnd1 Rpap3 Senp1 Sfxn4 Slc48a1 Spats2 Spmip11 Tmem106c Tuba1a Tuba1b Tuba1c Vdr Wnt1 Zfp641 Zfp950
Bone: periosteal perimeter	12.91	43	3	2.8	0.96	1.07e-107	Ablim1 Acsl5 Afap1l2 Asb8 Atrnl1 Cacnb3 Cacul1 Casp7 Ccdc186 Ces2c Dclre1a Dennd10 Fam204a Fhip2a Gfra1 Grk5 Habp2 Hdac7 Kansl2 Lmbr1l LOC102547573 LOC102548155 LOC102550729 LOC102551125 LOC103694460 LOC120093830 LOC120100065 Nhlrc2 Nrap Olr1877 Pfkm Plekhs1 Rapgef3 Rnd1 Rpap3 Senp1 Sfxn4 Slc48a1 Tmem106c Trub1 Tuba1c Zfp641 Zfp950
Bone: stiffness	16.25	50	32	29.6	0.99	0.00e+00	Adcy6 Arf3 Asb8 C7h12orf54 Cacnb3 Ccdc65 Ccnt1 Col2a1 Ddx23 Dhh Dnajc22 Endou Faim2 Fkbp11 Hdac7 Kansl2 Kcnh3 Klhdc8b Kmt2d Lmbr1l LOC100362820 LOC102546778 LOC102548155 LOC102556302 LOC103692978 LOC108351548 LOC120093728 LOC120093732 LOC120093830 Olr1877 Or8s2 Pced1b Pfkm Prkag1 Prph Rapgef3 Rhebl1 Rnd1 Rpap3 Senp1 Slc48a1 Spats2 Spmip11 Tmem106c Tuba1a Tuba1b Tuba1c Vdr Wnt1 Zfp641
Bone: trabecular number	13.03	4	0	0	1	5.26e-10	Hsph1 LOC102546827 LOC102549494 Rxfp2
Bone: trabecular thickness	16.33	3	0	0	1	1.03e-06	Cacul1 Prlhr Sfxn4
Time to tail flick, vehicle, after self-admin	37.57	1	1	0.9	0	1.00e+00	Klhdc8b
Total heroin consumption	18.89	1	0	0	0	1.00e+00	Klhdc8b
Delay disc. indifference point, 0s delay	28.7	1	1	0.9	0	1.00e+00	Klhdc8b
Delay disc. indifference point, 4s delay	41.82	1	1	0.9	0	1.00e+00	Klhdc8b
Rest time, locomotor task time 1	22.55	1	0	0	0	1.00e+00	Klhdc8b
Distance moved, locomotor task time 1	31.01	1	1	0.9	0	1.00e+00	Klhdc8b
Vertical activity count, locomotor time 1	49.01	1	1	0.9	0	1.00e+00	Klhdc8b
Bouts of movement, locomotor time 2	19.85	1	0	0	0	1.00e+00	Klhdc8b
Total resting periods, locomotor time 2	20.22	1	0	0	0	1.00e+00	Klhdc8b
Rest time, locomotor task time 2	25.34	1	1	0.9	0	1.00e+00	Klhdc8b
Distance moved, locomotor task time 2	42.39	1	1	0.9	0	1.00e+00	Klhdc8b
Vertical activity count, locomotor time 2	54.92	1	1	0.9	0	1.00e+00	Klhdc8b
Weight adjusted by age	30.32	1	1	0.9	0	1.00e+00	Klhdc8b
Food seeking constrained by brief footshock	21.42	2	2	1.9	1	6.39e-30	LOC102557269 RGD1359108
Cd content in liver	20.17	1	0	0	0	1.00e+00	Klhdc8b
Cu content in liver	31.36	2	1	0.9	0	1.00e+00	Cd99 LOC103694460
Fe content in liver	33.68	2	2	1.9	0	1.00e+00	Klhdc8b LOC103694460
K content in liver	34.63	2	1	0.9	0	1.00e+00	Cd99 LOC103694460
Rb content in liver	54.46	3	3	2.8	0	1.00e+00	Cd99 Klhdc8b LOC103694460
Sr content in liver	22.32	2	0	0	0	1.00e+00	Klhdc8b LOC103694460

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	76	2.1	4.2
Adipose	alternative TSS	53	1.6	3.98
Adipose	gene expression	137	1.5	3.99
Adipose	isoform ratio	68	1.5	3.83
Adipose	intron excision ratio	32	1	3.68
Adipose	mRNA stability	73	1.6	3.98
BLA	alternative polyA	59	2.7	4.46
BLA	alternative TSS	23	1.2	4.18
BLA	gene expression	119	1.8	4.29
BLA	isoform ratio	51	1.7	4.36
BLA	intron excision ratio	59	1.8	4.26
BLA	mRNA stability	44	1.8	4.43
Brain	alternative polyA	73	2	4.25
Brain	alternative TSS	76	1.9	4.37
Brain	gene expression	155	1.5	4.1
Brain	isoform ratio	90	1.6	4.28
Brain	intron excision ratio	84	1.4	4.06
Brain	mRNA stability	83	1.5	4.03
Eye	alternative polyA	8	2.7	4.77
Eye	alternative TSS	3	0.8	3.5
Eye	gene expression	15	1.2	4
Eye	isoform ratio	10	1.7	4.38
Eye	intron excision ratio	10	1.1	3.91
Eye	mRNA stability	8	2.2	4.12
IL	alternative polyA	22	2	4.82
IL	alternative TSS	10	1.5	4.4
IL	gene expression	61	1.5	4.17
IL	isoform ratio	22	1.8	4.4
IL	intron excision ratio	13	1.2	4.69
IL	mRNA stability	20	1.4	4.43
LHb	alternative polyA	33	3	4.84
LHb	alternative TSS	3	0.5	4.61
LHb	gene expression	65	1.8	4.17
LHb	isoform ratio	22	1.7	4.26
LHb	intron excision ratio	14	1.2	4.25
LHb	mRNA stability	14	1.1	4.01
Liver	alternative polyA	52	2	4.2
Liver	alternative TSS	42	1.6	4.17
Liver	gene expression	92	1.2	3.9
Liver	isoform ratio	63	1.7	4.3
Liver	intron excision ratio	53	1.1	3.62
Liver	mRNA stability	48	1.6	4.1
NAcc	alternative polyA	72	2.3	4.47
NAcc	alternative TSS	45	1.6	4.3
NAcc	gene expression	135	1.6	4.19
NAcc	isoform ratio	72	1.7	4.41
NAcc	intron excision ratio	71	1.4	4.3
NAcc	mRNA stability	45	1.4	4.25
OFC	alternative polyA	29	2.6	4.66
OFC	alternative TSS	12	1.7	5.03
OFC	gene expression	57	1.4	4.18
OFC	isoform ratio	20	1.5	4.4
OFC	intron excision ratio	20	1.7	5.2
OFC	mRNA stability	24	1.8	4.37
PL	alternative polyA	68	2.1	4.33
PL	alternative TSS	53	1.6	4.23
PL	gene expression	145	1.6	4.12
PL	isoform ratio	88	1.9	4.34
PL	intron excision ratio	88	1.6	4.49
PL	mRNA stability	54	1.4	4.1
pVTA	alternative polyA	34	2	4.38
pVTA	alternative TSS	25	1.9	4.29
pVTA	gene expression	91	1.7	4.32
pVTA	isoform ratio	33	1.5	4.17
pVTA	intron excision ratio	45	1.5	4.37
pVTA	mRNA stability	23	1.6	4.26
RMTg	alternative polyA	15	2.6	4.15
RMTg	alternative TSS	12	2.5	4.49
RMTg	gene expression	26	1.4	4.18
RMTg	isoform ratio	10	1.5	4.6
RMTg	intron excision ratio	18	2.2	4.72
RMTg	mRNA stability	7	1.1	4.17