Slc29a2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Slc29a2 0.34 0.11 0.0e+00 0.13 0.15 0.14 0.14 6.4e-14 5.8e-16 5.0e-15 2.0e-15
2 PL gene expression Slc29a2 0.48 0.16 0.0e+00 0.27 0.3 0.29 0.3 1.3e-29 5.5e-33 1.2e-31 1.5e-32
3 BLA gene expression Slc29a2 0.51 0.15 4.7e-12 0.23 0.22 0.21 0.22 1.5e-12 1.2e-11 2.3e-11 4.5e-12
4 NAcc gene expression Slc29a2 0.06 0.04 3.2e-09 0.06 0.06 0.06 0.06 5.2e-09 1.3e-09 8.5e-10 1.4e-09
5 Brain gene expression Slc29a2 0.05 0.03 9.4e-06 0.03 0.04 0.04 0.03 1.2e-03 5.2e-05 1.5e-04 6.2e-04
6 IL gene expression Slc29a2 0.16 0.12 5.2e-03 0.11 0.09 0.07 0.07 1.2e-03 3.4e-03 1.0e-02 8.9e-03
7 LHb alternative polyA XM_008760174.4 0.13 0.09 6.6e-03 0.12 0.04 0.07 0.01 1.1e-03 4.2e-02 7.9e-03 2.2e-01
8 OFC gene expression Slc29a2 0.19 0.12 1.2e-03 0.04 0.04 0.03 0.01 3.7e-02 4.2e-02 8.0e-02 1.9e-01
9 IC gene expression Slc29a2 0.24 0.17 8.2e-05 0.04 0.08 0.09 0.09 5.9e-03 3.1e-04 1.3e-04 1.4e-04
10 Adipose alternative polyA NM_031738.1 0.03 0.02 4.3e-03 0.01 0.01 0 0.01 1.1e-02 4.1e-02 1.1e-01 6.3e-02
11 Adipose alternative polyA XM_008760174.4 0.03 0.02 3.8e-03 0.01 0.01 0 0.01 9.2e-03 2.8e-02 8.5e-02 4.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.01.73.9-1.1-1.3-0.6-1.60.3-0.8-0.91.0-1.7-2.02.0
Area under the delay curve0.50.51.5-0.0-0.3-0.2-0.40.8-0.2-0.51.2-1.2-0.90.9
BMI with tail2.48.316.3-3.3-3.1-2.2-3.6-0.5-2.5-0.41.1-3.6-4.04.0
BMI without tail1.54.510.6-2.6-2.4-2.1-2.6-0.4-1.70.31.0-3.3-2.42.4
Body weight2.410.417.8-4.2-4.0-3.8-3.8-2.6-3.72.2-1.1-3.8-2.32.3
Weight adjusted by age1.11.72.8-1.5-1.3-1.7-1.5-1.7-1.61.5-1.5-0.60.1-0.1
Bone surface2.95.39.3-2.7-2.9-2.1-3.1-1.7-2.40.4-0.6-2.0-2.82.8
Bone volume1.22.14.7-1.5-1.7-0.9-2.2-0.6-1.2-0.40.1-1.3-2.12.1
Breakpoint value in progressive ratio session1.82.23.9-2.0-1.8-1.7-1.7-1.9-1.71.1-1.5-0.7-0.60.6
Number of licking bursts0.20.30.6-0.5-0.7-0.5-0.7-0.6-0.70.3-0.7-0.1-0.60.6
Context. condit. distance diff. score1.41.72.51.41.61.51.51.51.4-1.21.50.90.7-0.7
Locomotion velocity, session 10.20.20.9-0.1-0.2-0.4-0.7-0.2-0.00.9-0.1-0.70.3-0.3
Locomotion distance, session 11.11.33.5-1.1-1.2-1.0-1.30.1-0.7-0.00.8-1.9-1.51.5
Locomotion velocity, session 22.52.94.7-2.1-2.0-2.0-2.2-1.4-2.01.4-0.8-2.0-1.11.1
Locomotion distance, session 21.41.95.9-1.5-1.6-1.4-1.7-0.4-1.20.70.4-2.4-1.31.3
Locomotion velocity, session 30.30.30.70.10.10.2-0.70.70.0-0.50.7-0.5-0.80.8
Locomotion distance, session 30.10.10.60.1-0.1-0.1-0.80.1-0.20.10.0-0.2-0.40.4
Stereotopy head waving bouts, day 30.60.62.20.50.50.6-0.21.40.5-0.91.5-0.6-0.60.6
Stereotopy head waving duration, day 30.81.02.30.90.81.10.61.51.0-1.41.40.1-0.40.4
Locomotion velocity, session 70.50.51.9-0.20.20.4-0.50.90.3-0.91.4-0.5-0.90.9
Locomotion distance, session 70.30.41.3-0.7-0.5-0.5-0.70.3-0.60.20.8-1.1-0.30.3
Stereotopy head waving bouts, day 70.60.61.60.40.40.8-0.60.60.6-1.10.60.5-1.31.3
Stereotopy head waving duration, day 70.80.93.3-0.7-0.7-0.1-1.4-0.2-0.2-0.6-0.0-0.3-1.81.8
Locomotion velocity, session 81.01.21.8-1.1-1.3-1.3-1.0-1.1-1.21.3-0.9-1.2-0.10.1
Locomotion distance, session 80.20.31.20.30.50.50.40.80.5-0.61.1-0.1-0.10.1
Degree of sensitization distance0.30.30.7-0.6-0.4-0.3-0.40.3-0.2-0.20.8-0.8-0.50.5
Degree of sensitization stereotypy0.40.41.4-0.4-0.30.2-1.0-0.4-0.0-0.4-0.20.4-1.21.2
Conditioned locomotion1.61.83.2-1.8-1.5-1.8-1.1-1.6-1.61.7-0.9-1.30.2-0.2
Cocaine response after cond. corrected0.70.91.61.01.30.91.21.00.9-0.51.00.50.8-0.8
Cocaine response after cond. not corrected0.50.61.21.01.10.91.00.90.8-0.70.70.60.4-0.4
Cocaine response before conditioning0.40.51.2-0.5-0.8-0.5-0.9-0.8-0.70.1-1.10.1-0.80.8
Saline control response3.04.06.9-2.3-2.6-2.5-2.2-1.9-2.51.5-1.3-2.0-1.21.2
Bone: connectivity density2.33.66.1-2.2-2.4-1.7-2.2-0.8-1.7-0.10.4-2.3-2.52.5
Bone: cortical apparent density0.10.20.5-0.4-0.3-0.5-0.0-0.70.10.7-0.6-0.00.4-0.4
Bone: cortical area0.50.81.8-0.9-0.8-0.9-0.4-1.3-1.31.1-1.2-0.00.5-0.5
Bone: cortical porosity0.30.31.0-0.5-0.6-0.5-0.70.2-0.5-0.20.3-1.0-0.60.6
Bone: cortical porosity0.50.61.8-0.9-1.0-0.9-0.9-0.2-0.90.20.0-1.3-0.40.4
Bone: cortical thickness3.35.410.2-2.3-2.2-2.6-1.5-3.1-3.03.2-2.9-0.80.9-0.9
Bone: cortical thickness1.41.73.8-1.2-1.3-1.6-1.1-1.4-1.62.0-1.4-1.10.3-0.3
Bone: cortical tissue density0.20.30.8-0.5-0.5-0.6-0.2-0.8-0.10.9-0.8-0.20.4-0.4
Condit. Reinf. active minus inactive responses0.40.41.3-0.5-0.4-0.5-1.1-0.2-0.30.30.2-0.7-0.90.9
Condit. Reinf. active-inactive response ratio0.10.10.3-0.00.1-0.1-0.6-0.1-0.10.00.2-0.2-0.60.6
Condit. Reinf. active responses0.10.20.4-0.5-0.2-0.4-0.6-0.2-0.00.30.4-0.6-0.50.5
Condit. Reinf. inactive responses0.10.10.4-0.20.10.10.00.20.5-0.10.6-0.2-0.10.1
Incentive salience index mean0.40.51.0-0.9-0.7-0.7-1.0-0.3-0.50.30.4-1.0-0.80.8
Condit. Reinf. lever presses0.20.20.7-0.8-0.5-0.6-0.2-0.7-0.50.5-0.1-0.3-0.10.1
Condit. Reinf. active minus inactive responses0.50.71.60.80.51.0-0.10.60.8-1.30.31.0-1.01.0
Condit. Reinf. active-inactive response ratio1.31.52.71.41.31.60.71.01.6-1.50.61.6-0.40.4
Condit. Reinf. active responses0.60.93.3-0.0-0.40.3-1.00.4-0.1-1.20.30.0-1.81.8
Condit. Reinf. inactive responses1.21.63.0-1.2-1.4-0.9-1.6-0.1-1.4-0.30.1-1.6-1.71.7
Condit. Reinf. lever presses1.31.84.2-1.3-1.6-1.0-2.0-1.2-1.30.4-1.0-0.5-1.71.7
Condit. Reinf. lever reinforcers received0.60.93.3-0.3-0.60.0-1.20.1-0.4-0.9-0.0-0.0-1.81.8
Conditioned reinforcement - actives0.20.31.30.50.30.50.2-0.30.4-0.1-0.81.20.6-0.6
Conditioned reinforcement - inactives2.23.26.02.52.32.31.61.62.3-1.60.92.00.4-0.4
Conditioned locomotion6.38.214.23.83.53.43.52.73.3-2.21.62.81.8-1.8
Patch foraging indifference point 0 sec0.10.20.70.40.20.30.40.5-0.1-0.80.40.3-0.40.4
Patch foraging indifference point AUC1.21.73.8-1.7-1.5-1.3-1.5-2.0-1.21.3-1.6-0.2-0.40.4
Delay disc. indifference point, 0s delay0.70.83.30.30.10.10.31.40.2-0.61.8-1.5-0.40.4
Delay disc. indifference point, 16s delay0.70.81.71.00.81.00.31.20.9-1.31.10.5-0.70.7
Delay disc. indifference point, 2s delay0.20.20.50.50.20.40.30.70.1-0.60.7-0.1-0.40.4
Delay disc. indifference point, 24s delay0.10.20.4-0.0-0.2-0.40.20.1-0.50.50.2-0.60.5-0.5
Delay disc. indifference point, 4s delay0.50.52.3-0.1-0.3-0.30.00.8-0.3-0.31.3-1.5-0.40.4
Delay disc. indifference point, 8s delay0.30.41.6-0.1-0.4-0.3-0.20.6-0.1-0.21.0-1.3-0.50.5
Indifference point function ln k3.66.311.03.33.32.73.03.12.3-1.82.21.31.8-1.8
Indifference point function log k3.66.311.03.33.32.73.03.12.3-1.82.21.31.8-1.8
Patch foraging total patch changes 0 sec0.00.00.10.20.1-0.00.30.1-0.3-0.20.00.20.1-0.1
Patch foraging total patch changes 12 sec2.93.77.4-2.7-2.6-2.2-2.2-2.1-2.11.2-1.3-1.3-1.31.3
Patch foraging total patch changes 18 sec0.40.61.1-1.0-0.9-0.7-1.1-0.6-0.80.0-0.4-0.5-1.01.0
Patch foraging total patch changes 24 sec1.01.63.0-1.6-1.6-1.6-1.3-1.7-1.41.3-1.4-0.4-0.20.2
Patch foraging total patch changes 6 sec1.11.63.5-1.5-1.5-1.3-1.9-1.0-1.40.5-0.5-1.0-1.31.3
Patch foraging time to switch 0 sec1.22.55.2-2.0-1.9-1.4-1.7-0.7-0.9-0.10.2-1.9-2.32.3
Patch foraging water rate 0 sec2.96.110.03.13.12.43.21.52.1-0.60.42.82.9-2.9
Patch foraging water rate 12 sec4.28.816.83.93.62.84.12.62.6-1.01.42.13.4-3.4
Patch foraging water rate 18 sec1.52.34.52.12.01.41.91.61.3-0.60.91.01.7-1.7
Patch foraging water rate 24 sec3.54.98.12.72.82.02.91.62.2-0.50.81.92.7-2.7
Patch foraging water rate 6 sec2.84.18.02.62.51.62.81.51.30.10.61.22.8-2.8
Seeking ratio, delayed vs. immediate footshock0.40.51.10.1-0.1-0.30.10.70.1-0.61.1-1.0-1.01.0
Distance traveled before self-admin0.30.41.5-0.5-0.7-0.1-0.7-0.3-0.5-0.4-0.0-0.0-1.21.2
Distance traveled after self-admin0.20.20.7-0.2-0.30.1-0.7-0.40.3-0.0-0.20.4-0.90.9
Extensor digitorum longus weight5.822.837.4-6.1-5.6-5.8-5.4-5.4-5.64.9-3.7-3.9-1.61.6
Bone: elastic displacement0.80.92.80.70.80.21.1-0.10.51.0-0.20.61.7-1.7
Bone: elastic work1.41.84.5-1.4-1.3-1.7-0.7-1.7-1.62.1-1.2-0.90.4-0.4
Bone: endosteal estimation1.02.25.71.21.21.50.82.11.4-2.12.4-0.0-0.80.8
Bone: endosteal perimeter1.73.67.91.81.72.30.52.41.9-2.82.40.9-1.51.5
Epididymis fat weight3.411.517.44.14.14.24.13.33.8-3.22.43.51.6-1.6
Delta time in closed arm before/after self-admin0.90.82.1-1.1-1.0-1.3-0.8-0.5-1.11.10.0-1.50.2-0.2
Delta time in open arm before/after self-admin0.30.31.00.10.10.5-0.6-0.50.5-0.2-0.71.0-0.20.2
Diff in mean of infusions in LGA sessions0.30.41.2-0.9-0.8-0.5-0.1-1.1-0.50.5-0.90.10.4-0.4
Delay discount exponential model param0.40.41.40.10.40.30.4-0.60.20.3-1.01.20.8-0.8
Extinction: sum of active levers before priming1.41.63.5-1.9-1.7-1.4-1.4-1.2-1.60.4-0.7-1.0-0.80.8
Active lever presses in extinction session 61.81.83.6-1.5-1.3-1.4-1.6-1.9-1.31.2-1.9-0.0-0.70.7
Bone: final force1.52.43.7-1.9-1.9-1.8-1.9-1.7-1.81.4-1.0-1.4-0.80.8
Bone: final moment1.42.33.5-1.9-1.9-1.8-1.7-1.6-1.81.4-1.0-1.4-0.70.7
Food consumed during 24 hour testing period0.30.41.40.50.30.30.3-0.50.10.2-1.11.20.6-0.6
Glucose2.13.47.91.71.62.01.02.71.8-2.42.8-0.3-1.11.1
Heart weight1.32.07.70.50.40.70.42.20.8-1.82.8-1.3-1.21.2
Delay discount hyperbolic model param0.40.41.30.00.30.20.4-0.70.20.4-1.01.10.8-0.8
Intermittent access intake day 1-15 change1.02.03.61.81.81.51.60.81.9-0.80.31.90.9-0.9
Intermittent access intake escalation0.91.84.01.71.71.51.40.61.8-0.60.12.00.9-0.9
Intermittent access intake escalation 21.82.04.51.71.81.71.50.61.8-0.70.12.11.0-1.0
Intermitt. access day 1 inactive lever presses0.10.30.70.60.70.80.20.20.8-0.30.10.8-0.10.1
Intermitt. access day 15 inactive lever presses0.91.93.91.71.71.90.71.32.0-1.41.01.5-0.60.6
Intermitt. access escalation Index2.02.85.31.91.71.81.82.31.5-1.72.20.41.1-1.1
Intermittent access day 1 total infusions2.13.48.11.61.32.00.82.71.7-2.82.80.0-1.21.2
Intermittent access day 15 total infusions3.75.58.92.92.73.02.12.53.0-2.62.02.20.3-0.3
Intermittent access terminal intake (last 3 days)3.74.98.92.62.43.01.52.52.8-2.72.11.9-0.40.4
Intermittent access total infusions2.83.36.42.01.72.21.02.42.0-2.52.30.9-0.70.7
Intermittent access day 1 locomotion1.72.24.51.31.21.60.52.11.5-2.12.10.1-1.21.2
Intermittent access day 15 total locomotion2.54.67.42.72.52.61.72.42.7-2.61.91.9-0.20.2
Intermittent access total locomotion5.76.811.03.12.93.21.93.23.2-3.32.81.8-0.70.7
Intermittent access standard deviation0.61.32.61.61.61.41.11.01.6-0.60.51.30.4-0.4
Left kidney weight0.73.46.81.92.11.92.62.02.2-1.52.01.11.3-1.3
Right kidney weight0.62.67.51.71.71.42.71.01.5-0.70.51.41.9-1.9
Cocaine induced anxiety0.10.10.4-0.00.00.1-0.5-0.20.40.0-0.30.3-0.60.6
Post-drug Anxiety0.40.40.8-0.7-0.8-0.5-0.8-0.9-0.40.4-0.90.1-0.60.6
Baseline Anxiety0.30.30.7-0.6-0.8-0.50.0-0.7-0.90.5-0.7-0.20.4-0.4
Tail length0.62.25.8-1.4-1.3-1.9-0.6-1.8-1.22.4-1.4-1.31.2-1.2
Length with tail1.66.912.1-3.0-2.8-3.3-2.0-3.3-3.13.5-2.6-2.00.5-0.5
Length without tail1.85.910.1-2.6-2.6-2.9-2.3-2.9-3.23.0-2.7-1.70.1-0.1
Times rat made contact with spout0.70.91.9-1.0-1.1-1.1-1.0-0.4-1.20.40.0-1.4-0.80.8
Lifetime Intake1.82.24.61.51.31.80.82.11.5-2.12.10.4-0.60.6
Liver weight, left0.61.02.20.91.00.71.50.81.00.00.70.11.5-1.5
Liver weight, right0.91.62.91.61.51.11.71.71.0-0.51.3-0.11.2-1.2
Locomotor activity0.91.42.81.61.30.81.51.01.10.20.40.61.7-1.7
Locomotor testing distance0.91.63.21.81.40.91.51.21.10.20.70.31.8-1.8
Locomotor testing rearing0.71.43.21.71.21.31.21.81.2-0.81.4-0.10.5-0.5
Locomotion in novel chamber4.35.59.43.12.82.92.72.52.9-2.11.81.90.9-0.9
Locomotion in novel chamber post-restriction2.13.45.92.32.12.41.91.92.3-1.81.41.70.7-0.7
Fecal boli incidents, locomotor time 10.30.42.30.30.50.7-0.5-0.20.4-0.4-0.61.5-0.30.3
Change in fecal boli incidents, locomotor task0.30.31.7-0.3-0.5-0.70.20.4-0.3-0.00.7-1.3-0.10.1
Time >=10cm from walls, locomotor time 11.51.63.51.11.01.0-0.11.51.4-1.91.50.5-1.41.4
Bouts of movement, locomotor time 10.70.81.8-1.0-0.9-1.1-1.2-1.3-0.30.8-1.2-0.1-0.40.4
Total resting periods, locomotor time 10.40.51.1-0.7-0.6-0.7-1.1-1.0-0.20.4-0.90.2-0.60.6
Rest time, locomotor task time 11.41.83.61.91.71.71.31.11.7-0.80.31.50.8-0.8
Distance moved, locomotor task time 10.50.71.5-0.7-0.7-0.5-0.90.2-0.6-0.30.7-1.2-1.21.2
Vertical activity count, locomotor time 10.20.40.80.70.70.50.90.80.5-0.50.60.10.5-0.5
Time >=10cm from walls, locomotor time 20.10.10.50.30.30.30.00.00.4-0.3-0.10.7-0.20.2
Bouts of movement, locomotor time 20.40.61.5-0.9-0.9-0.7-1.2-0.6-0.60.3-0.4-0.6-0.80.8
Total resting periods, locomotor time 20.20.31.0-0.6-0.6-0.3-1.0-0.3-0.2-0.0-0.0-0.4-0.90.9
Rest time, locomotor task time 21.62.04.21.81.71.71.21.62.0-1.21.30.90.5-0.5
Distance moved, locomotor task time 20.80.91.8-1.1-1.0-1.3-0.6-1.3-1.21.0-1.2-0.5-0.00.0
Vertical activity count, locomotor time 20.70.92.6-0.1-0.1-0.70.8-0.8-0.31.2-1.30.21.6-1.6
Light reinforcement 10.00.10.30.40.20.10.60.40.1-0.2-0.10.10.4-0.4
Light reinforcement 20.81.33.21.61.51.51.00.81.0-0.90.21.80.4-0.4
Bone: marrow area1.12.36.21.31.21.60.92.21.4-2.22.5-0.1-0.80.8
Bone: maximum diameter0.10.21.20.30.20.40.3-0.4-0.1-0.2-0.61.10.3-0.3
Bone: maximum force2.13.66.9-2.2-2.2-1.8-2.6-1.6-2.00.8-0.7-1.4-2.32.3
Bone: maximum moment1.93.46.3-2.2-2.1-1.8-2.5-1.5-2.00.8-0.6-1.5-2.12.1
Mean time between licks in bursts0.30.71.5-0.7-0.9-1.1-0.5-0.6-1.20.9-0.6-1.10.2-0.2
Mean num. licks in bursts0.10.20.90.10.20.20.30.70.4-0.30.9-0.60.1-0.1
Cd content in liver1.41.53.11.51.31.41.41.21.8-1.50.71.30.2-0.2
Co content in liver1.01.13.81.11.10.60.80.40.70.7-0.10.62.0-2.0
Cu content in liver0.10.10.3-0.2-0.2-0.1-0.40.3-0.5-0.40.2-0.2-0.60.6
Fe content in liver0.20.30.5-0.4-0.5-0.5-0.6-0.7-0.50.6-0.70.00.2-0.2
K content in liver0.80.81.7-1.0-0.9-0.8-1.3-0.3-1.10.30.4-1.1-0.90.9
Mg content in liver0.40.41.00.40.30.4-0.70.9-0.1-0.61.0-0.4-0.70.7
Mn content in liver2.12.45.0-1.8-1.7-1.4-2.2-2.0-1.61.1-1.4-0.3-1.21.2
Na content in liver0.50.62.1-0.1-0.1-0.40.1-1.0-0.60.8-1.40.90.8-0.8
Rb content in liver1.01.23.11.21.01.20.01.80.9-1.31.7-0.2-0.60.6
Se content in liver0.30.30.70.60.50.80.30.40.5-0.80.30.8-0.40.4
Sr content in liver1.71.43.3-1.3-1.2-1.4-0.5-1.8-1.41.4-1.7-0.10.4-0.4
Zn content in liver0.30.30.8-0.8-0.7-0.7-0.2-0.4-0.90.4-0.0-0.7-0.00.0
Bone: minimum diameter1.32.46.30.90.91.30.12.01.1-2.22.5-0.4-1.71.7
Time in familiar zone, hab. session 10.40.40.70.50.50.6-0.30.70.7-0.80.60.3-0.70.7
Time in novel zone, hab. session 10.30.31.10.30.2-0.00.80.1-0.30.4-0.3-0.01.0-1.0
Total zone transitions, hab. session 10.60.81.3-1.2-1.0-1.1-1.0-0.8-0.80.8-0.4-1.1-0.60.6
Total locomotion distance, hab. session 10.30.41.20.50.80.70.50.81.1-0.61.00.2-0.00.0
Locomotion velocity, hab. session 10.10.10.4-0.10.20.10.00.30.6-0.20.7-0.2-0.20.2
Time in familiar zone, hab. session 20.20.20.5-0.3-0.2-0.5-0.6-0.3-0.50.7-0.5-0.40.3-0.3
Time in novel zone, hab. session 20.20.20.4-0.1-0.20.10.20.30.1-0.60.7-0.3-0.70.7
Total zone transitions, hab. session 22.83.69.1-1.7-1.9-1.2-2.40.1-0.7-0.60.8-2.6-3.03.0
Total locomotion distance, hab. session 20.91.23.1-0.3-0.3-0.1-1.11.00.3-1.01.3-1.3-1.81.8
Locomotion velocity, hab. session 20.91.12.9-0.00.00.2-0.81.20.6-1.21.4-1.0-1.71.7
Novel to familiar place preference ratio0.30.30.8-0.6-0.5-0.0-0.2-0.7-0.3-0.4-0.40.5-0.90.9
Novelty place preference0.20.20.7-0.2-0.20.30.1-0.30.0-0.7-0.10.6-0.80.8
Time in novel zone, NPP test0.20.20.6-0.2-0.20.30.2-0.20.1-0.70.00.5-0.80.8
Total zone transitions, NPP test1.82.64.6-2.0-2.0-1.8-2.2-1.0-1.40.8-0.2-2.0-1.61.6
Total locomotion distance, NPP test0.30.41.3-0.5-0.4-0.4-0.70.30.10.10.8-1.2-0.60.6
Locomotion velocity, NPP test0.20.31.0-0.5-0.4-0.4-0.60.10.00.10.7-1.0-0.60.6
Intraocular pressure1.52.14.81.61.71.81.60.52.2-0.7-0.22.21.1-1.1
Delta distance traveled before/after self-admin0.10.10.40.20.20.10.2-0.10.50.3-0.10.20.7-0.7
Delta ambulatory time before/after self-admin0.00.10.2-0.0-0.0-0.1-0.1-0.20.10.4-0.30.10.4-0.4
Parametrial fat weight3.07.011.62.93.03.32.83.13.4-2.82.81.70.6-0.6
Pavlov. Cond. lever latency0.20.30.70.70.60.50.80.40.6-0.30.10.60.5-0.5
Pavlov. Cond. magazine entry latency0.30.41.5-0.4-0.3-0.1-0.70.2-0.0-0.50.4-0.4-1.21.2
Pavlov. Cond. change in total contacts0.20.20.60.10.30.5-0.0-0.00.4-0.6-0.10.8-0.60.6
Pavlov. Cond. index score0.00.10.1-0.3-0.1-0.1-0.3-0.3-0.10.1-0.40.1-0.30.3
Pavlov. Cond. latency score0.00.10.2-0.3-0.1-0.0-0.4-0.1-0.2-0.0-0.1-0.1-0.40.4
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.3-0.2-0.5-0.1-0.40.10.1-0.4-0.40.4
Pavlov. Cond. magazine entry number0.10.10.60.20.10.10.30.60.1-0.30.7-0.40.2-0.2
Pavlov. Cond. intertrial magazine entries0.40.51.00.70.60.61.00.11.0-0.20.11.00.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.4-0.3-0.2-0.3-0.4-0.30.1-0.4-0.1-0.40.4
Pavlov. Cond. response bias0.10.10.4-0.2-0.1-0.2-0.1-0.5-0.10.3-0.60.3-0.00.0
Pavlov. Cond. lever latency0.30.41.00.50.70.40.80.90.6-0.61.0-0.10.2-0.2
Pavlov. Cond. magazine entry latency3.84.69.1-2.5-2.5-2.1-3.0-1.8-2.21.1-1.3-1.8-2.22.2
Pavlov. Cond. change in total contacts0.81.33.4-1.1-1.2-0.6-1.8-1.1-0.70.0-1.00.0-1.71.7
Pavlov. Cond. index score1.62.24.9-1.7-1.7-1.3-2.2-1.5-1.40.8-1.2-0.8-1.61.6
Pavlov. Cond. latency score1.41.84.1-1.5-1.5-1.2-2.0-1.5-1.30.8-1.2-0.7-1.41.4
Pavlov. Cond. lever contacts0.30.41.0-0.6-0.7-0.5-0.9-0.9-0.60.5-1.00.0-0.50.5
Pavlov. Cond. magazine entry number5.16.312.22.93.02.63.52.52.6-1.41.91.72.4-2.4
Pavlov. Cond. intertrial magazine entries0.91.32.01.41.41.31.41.11.4-0.90.71.10.7-0.7
Pavlov. Cond. lever-magazine prob. diff.2.02.75.9-1.9-1.9-1.5-2.4-1.7-1.60.9-1.3-1.0-1.71.7
Pavlov. Cond. response bias1.41.94.2-1.5-1.6-1.2-2.0-1.4-1.30.7-1.3-0.7-1.41.4
Time in closed arm before self-admin0.50.61.20.90.71.10.30.90.5-1.10.60.6-0.80.8
Time in closed arm after self-admin0.10.10.40.20.30.1-0.10.4-0.2-0.10.6-0.3-0.00.0
Time in open arm before self-admin0.50.51.8-0.3-0.3-0.80.70.2-0.40.90.5-1.30.9-0.9
Time in open arm after self-admin0.10.10.2-0.3-0.4-0.2-0.1-0.30.10.4-0.4-0.2-0.00.0
Bone: periosteal estimation0.10.10.30.20.30.40.30.40.1-0.60.60.2-0.20.2
Bone: periosteal perimeter0.20.31.00.00.00.3-0.60.1-0.3-0.70.30.4-1.01.0
Bone: post-yield work2.53.612.5-0.8-0.60.3-1.31.10.2-2.52.0-0.9-3.53.5
Progressive ratio test 1 active lever presses0.10.20.50.40.20.60.10.50.5-0.70.40.30.1-0.1
Progressive ratio test 1 breakpoint0.10.10.40.30.20.50.00.40.4-0.70.30.30.1-0.1
Progressive ratio test 1 inactive lever presses0.10.10.20.30.30.20.00.20.4-0.40.10.4-0.40.4
Progressive ratio test 2 active lever presses1.82.13.61.81.61.91.11.61.7-1.81.21.3-0.40.4
Progressive ratio test 2 breakpoint1.72.03.51.81.61.91.11.51.7-1.71.11.4-0.30.3
Progressive ratio test 2 inactive lever presses4.87.812.63.63.23.42.73.23.5-3.12.52.20.1-0.1
Incentive Sensitization - Responses0.30.41.80.10.00.2-0.50.4-0.1-0.70.40.0-1.31.3
Incentive Sensitization - Breakpoint0.30.51.60.30.30.4-0.30.50.1-0.80.50.3-1.31.3
Sum of active levers in priming session hrs 5-62.11.97.0-0.10.0-0.5-0.1-2.1-0.11.3-2.72.11.3-1.3
Progressive ratio1.42.24.9-1.4-1.4-1.1-1.80.2-0.6-0.71.1-2.0-2.22.2
Food seeking constrained by brief footshock0.30.30.7-0.6-0.5-0.9-0.3-0.4-0.60.6-0.2-0.7-0.50.5
Seeking ratio, punishment vs. effort0.91.33.01.21.20.71.70.30.50.6-0.31.01.7-1.7
Retroperitoneal fat weight7.029.946.26.86.66.66.36.46.3-5.05.03.92.4-2.4
Reaction time number correct0.30.51.3-0.2-0.2-0.6-0.2-0.9-0.91.0-1.10.30.7-0.7
Reaction time mean minus median1.02.44.1-2.0-1.9-1.6-1.7-2.0-1.21.1-1.8-0.7-1.11.1
Reaction time mean minus median AUC0.61.63.3-1.5-1.4-1.5-1.1-1.8-1.11.4-1.8-0.5-0.20.2
Reaction time num false alarms0.30.41.50.10.3-0.20.40.00.00.80.1-0.31.2-1.2
Reaction time num false alarms AUC0.40.61.8-0.6-0.4-0.9-0.4-0.6-0.61.3-0.3-0.90.8-0.8
Reaction time trials correct on left0.30.51.3-0.2-0.2-0.6-0.2-0.9-0.91.0-1.10.30.7-0.7
Reaction time trials on left0.30.61.6-0.3-0.3-0.7-0.3-1.1-1.01.1-1.30.30.7-0.7
Reaction time mean0.10.10.7-0.0-0.20.00.1-0.10.8-0.1-0.50.0-0.20.2
Reaction time mean AUC0.10.10.80.1-0.00.20.2-0.00.9-0.3-0.40.2-0.30.3
Median of all reaction times0.20.31.80.50.40.60.40.51.3-0.60.10.2-0.20.2
Reaction time omissions1.31.83.3-1.8-1.7-1.4-1.4-1.8-1.21.3-1.6-0.8-0.60.6
Reaction time false alarm rate0.10.20.6-0.20.0-0.2-0.00.10.10.60.5-0.80.6-0.6
Reaction time premature initiation rate2.53.56.3-2.2-2.4-2.5-2.0-1.8-2.02.0-1.5-1.9-0.40.4
Reaction time premature initiations2.85.08.7-2.4-2.6-3.0-2.1-2.6-2.72.7-2.4-1.60.1-0.1
Std. dev. reaction times0.40.71.4-1.0-1.1-0.8-0.7-1.1-0.20.6-1.2-0.4-0.60.6
Reaction time trials completed0.30.61.6-0.3-0.3-0.7-0.3-1.1-1.01.1-1.30.30.7-0.7
Reaction time trials AUC0.20.51.2-0.2-0.2-0.6-0.2-0.9-0.91.0-1.10.30.7-0.7
Run reversals in cocaine runway, females1.51.54.2-1.2-1.0-1.4-1.3-0.0-1.40.50.7-2.1-1.21.2
Run reversals in cocaine runway, males0.80.81.80.60.70.30.7-0.50.21.1-1.01.01.4-1.4
Latency to leave start box in cocaine runway0.60.71.90.10.10.8-0.50.70.6-1.10.9-0.1-1.41.4
Latency to leave start box in cocaine runway, F0.30.30.9-0.0-0.00.5-0.10.50.3-0.70.7-0.3-0.90.9
Latency to leave start box in cocaine runway, M0.30.30.9-0.2-0.10.2-0.9-0.10.2-0.2-0.00.1-1.01.0
Std. dev. time between licks in bursts0.40.61.4-0.3-0.4-0.70.3-0.3-0.51.1-0.4-0.91.2-1.2
Total sessions with >9 infusions0.30.40.8-0.4-0.4-0.2-0.70.5-0.2-0.70.9-0.8-0.80.8
Short access day 1 total inactive lever presses1.52.02.91.71.51.71.71.71.5-1.51.41.00.4-0.4
Short access day 10 total inactive lever presses0.10.20.40.50.60.50.20.50.5-0.10.60.1-0.40.4
Short access day 1 total infusions1.11.53.81.11.11.50.91.80.8-1.71.90.3-0.40.4
Short access day 10 total infusions1.31.74.50.1-0.00.6-0.61.50.3-1.92.1-0.8-1.81.8
Short access total infusions0.60.72.70.10.10.4-0.11.20.1-1.31.6-0.7-0.90.9
Short access day 1 locomotion0.91.12.21.11.01.30.11.50.9-1.41.50.3-0.80.8
Short access day 10 total locomotion0.71.32.51.01.11.00.21.51.1-1.41.60.4-1.21.2
Short access total locomotion1.11.42.61.11.11.30.31.61.2-1.61.60.4-0.90.9
One hour access (0.3 mA shock)4.45.08.42.92.72.82.22.72.8-2.22.21.50.3-0.3
Compulsive drug intake2.52.95.6-1.8-1.8-2.2-1.4-1.8-1.92.4-1.6-1.80.6-0.6
One hour access (shock baseline)5.07.612.73.43.33.62.73.03.3-3.02.42.50.2-0.2
Social response proportion0.60.61.5-0.7-0.8-0.6-1.2-0.6-0.7-0.0-0.4-0.3-1.21.2
Social responses0.20.30.5-0.5-0.6-0.6-0.7-0.6-0.70.5-0.6-0.4-0.30.3
Social time0.30.40.8-0.6-0.7-0.8-0.1-0.8-0.70.8-0.9-0.60.2-0.2
Soleus weight3.08.813.73.63.73.23.73.13.4-1.92.52.02.3-2.3
Bone: stiffness1.62.55.0-1.8-1.8-1.2-2.2-1.1-1.60.1-0.5-1.1-2.22.2
Tibialis anterior weight7.525.343.9-5.9-5.7-6.0-5.0-6.6-5.76.0-5.5-2.8-0.10.1
Time to tail flick, vehicle, before self-admin0.50.51.7-0.6-0.5-0.5-1.3-0.0-0.60.00.4-0.7-1.01.0
Time to tail flick, vehicle, after self-admin1.01.34.0-1.3-1.2-1.0-1.00.1-0.9-0.11.1-2.0-1.31.3
Time to tail flick, test, before self-admin1.61.66.10.90.80.80.31.90.9-1.42.5-0.7-1.11.1
Time to tail flick, test, after self-admin0.10.10.40.20.20.2-0.3-0.20.4-0.1-0.30.60.1-0.1
Delta time to tail flick, vehicle, before/after SA0.60.61.3-0.9-0.9-0.7-0.6-0.1-0.50.00.4-1.2-1.11.1
Delta time to tail flick, test, before/after SA2.32.38.0-0.6-0.6-0.8-0.2-2.2-0.51.8-2.81.21.9-1.9
Tibia length0.61.65.4-1.0-1.0-1.1-0.1-2.1-0.51.3-2.30.51.2-1.2
Ambulatory time before self-admin0.40.52.2-0.3-0.40.2-0.8-0.2-0.0-0.6-0.00.2-1.51.5
Ambulatory time after self-admin0.81.01.70.70.61.2-0.10.81.3-1.30.80.8-1.21.2
Bone: tissue strength0.10.10.30.10.00.10.00.20.1-0.40.30.2-0.50.5
Total heroin consumption2.73.15.9-2.4-2.3-2.0-1.6-2.3-2.11.3-1.9-0.8-0.50.5
Bone: trabecular number0.91.64.1-1.2-1.4-0.6-1.6-0.1-0.7-0.80.5-1.2-2.02.0
Bone: trabecular spacing0.20.30.90.50.50.20.90.40.50.30.1-0.10.7-0.7
Bone: trabecular thickness0.50.62.10.50.40.7-0.31.10.3-1.41.1-0.0-0.70.7
Bone: trabecular tissue density3.75.59.22.93.02.62.71.82.8-1.11.02.32.2-2.2
Water consumed over 24 hours0.81.12.3-1.1-1.4-1.3-1.1-1.0-1.50.8-1.0-1.1-0.60.6
Number of responses in last shaping day0.00.00.2-0.1-0.20.2-0.1-0.1-0.40.3-0.3-0.1-0.00.0