Hub : Genes

Slc29a2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Slc29a2 0.04 0.03 6.7e-05 0.03 0.03 0.03 0.02 4.4e-04 1.9e-04 4.9e-04 8.8e-04
2 IL gene expression Slc29a2 0.16 0.11 4.3e-03 0.11 0.11 0.06 0.06 1.3e-03 1.6e-03 1.2e-02 1.4e-02
3 Brain gene expression Slc29a2 0.05 0.03 4.0e-05 0.02 0.03 0.03 0.02 6.8e-03 1.2e-03 4.4e-04 1.0e-02
4 BLA gene expression Slc29a2 0.46 0.16 1.6e-11 0.22 0.22 0.21 0.23 4.0e-12 4.9e-12 1.5e-11 2.2e-12
5 Liver gene expression Slc29a2 0.32 0.11 0.0e+00 0.14 0.14 0.13 0.13 8.1e-15 8.5e-15 6.1e-14 2.2e-14
6 PL gene expression Slc29a2 0.39 0.13 0.0e+00 0.3 0.28 0.28 0.29 3.3e-33 1.9e-31 3.1e-31 4.9e-32
7 OFC gene expression Slc29a2 0.17 0.11 1.9e-03 0.1 0.05 0.08 0.04 2.2e-03 2.3e-02 6.1e-03 3.2e-02
8 PL isoform ratio NM_031738.1 0.03 0.03 4.9e-03 0.02 0 0.01 0.01 4.5e-03 8.9e-02 2.7e-02 3.7e-02
9 Adipose alternative polyA NM_031738.1 0.04 0.03 1.8e-03 0.01 0.01 0 0.01 7.6e-03 1.3e-02 8.7e-02 1.7e-02
10 Adipose alternative polyA XM_008760174.3 0.04 0.03 2.7e-03 0.01 0.01 0.01 0.01 2.2e-02 1.9e-02 6.6e-02 4.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.42.47.2-0.40.7-0.5-0.30.60.6-1.22.62.72.6
Area under the delay curve0.50.61.60.5-0.5-1.00.10.00.0-1.30.61.11.0
BMI with tail2.89.022.1-2.42.60.8-2.42.92.9-0.53.64.74.3
BMI without tail1.22.56.2-1.21.40.4-1.41.71.7-0.41.72.52.2
Body weight2.711.417.0-4.14.03.3-3.94.04.02.32.22.82.1
Weight adjusted by age2.12.45.3-1.91.81.8-2.31.51.51.90.30.40.1
Bone surface3.05.311.4-2.32.61.3-1.62.02.00.53.43.02.8
Bone volume1.62.78.7-1.11.40.3-0.60.90.9-0.32.92.52.5
Breakpoint value in progressive ratio session2.42.64.4-2.12.11.9-1.61.81.81.71.10.80.5
Number of licking bursts0.20.20.4-0.60.50.4-0.40.60.60.50.60.30.4
Context. condit. distance diff. score1.31.63.01.7-1.7-1.51.4-1.2-1.2-1.4-0.7-0.9-0.3
Locomotion velocity, session 10.30.31.0-0.1-0.40.2-0.50.40.40.3-1.0-0.7-0.7
Locomotion distance, session 10.91.23.9-0.60.4-0.1-0.91.11.1-0.51.22.01.6
Locomotion velocity, session 22.12.53.9-1.91.81.4-1.92.02.01.00.91.31.0
Locomotion distance, session 21.01.44.0-1.00.90.4-1.31.31.3-0.00.92.01.3
Locomotion velocity, session 30.20.30.60.3-0.3-0.60.10.20.2-0.80.40.70.8
Locomotion distance, session 30.00.00.00.1-0.2-0.20.10.10.1-0.20.00.00.0
Stereotopy head waving bouts, day 30.60.82.21.0-1.0-1.20.6-0.5-0.5-1.50.10.80.6
Stereotopy head waving duration, day 30.91.12.21.3-1.2-1.41.0-1.1-1.1-1.50.10.40.5
Locomotion velocity, session 70.60.71.60.6-0.4-1.00.5-0.4-0.4-1.20.61.21.1
Locomotion distance, session 70.20.20.6-0.00.1-0.3-0.40.40.4-0.6-0.10.80.6
Stereotopy head waving bouts, day 70.60.71.50.6-0.4-0.81.1-0.8-0.8-0.91.20.50.8
Stereotopy head waving duration, day 71.01.24.8-0.81.10.2-0.20.60.6-0.32.21.41.7
Locomotion velocity, session 81.01.22.8-1.21.01.2-1.41.71.70.9-0.2-0.0-0.2
Locomotion distance, session 80.20.30.60.6-0.8-0.70.3-0.3-0.3-0.70.00.30.4
Degree of sensitization distance0.20.21.0-0.00.2-0.3-0.30.20.2-0.60.31.00.8
Degree of sensitization stereotypy0.50.52.5-0.50.90.30.20.30.30.01.60.61.0
Conditioned locomotion1.72.03.5-1.71.61.9-1.61.51.51.8-0.30.1-0.4
Cocaine response after cond. corrected0.70.71.41.2-1.1-1.00.8-0.8-0.8-1.0-0.8-0.4-0.4
Cocaine response after cond. not corrected0.60.61.21.1-1.0-1.10.7-0.7-0.7-1.1-0.4-0.3-0.1
Cocaine response before conditioning0.30.41.2-0.70.70.5-0.50.50.50.51.10.20.6
Saline control response2.83.76.3-2.31.91.8-2.42.52.51.21.11.41.1
Bone: connectivity density2.64.010.3-1.61.90.5-1.21.61.6-0.42.93.22.9
Bone: cortical apparent density0.20.30.5-0.70.70.7-0.70.50.50.6-0.2-0.1-0.2
Bone: cortical area0.61.02.3-1.21.21.4-0.80.90.91.50.0-0.1-0.4
Bone: cortical porosity0.40.51.8-0.10.1-0.3-0.20.30.3-0.61.01.31.1
Bone: cortical porosity0.60.72.1-0.60.60.3-0.80.80.8-0.20.91.51.0
Bone: cortical thickness3.55.79.8-2.82.73.1-2.62.62.63.1-0.9-0.5-1.2
Bone: cortical thickness1.71.92.6-1.41.31.6-1.61.51.51.6-1.3-0.9-1.1
Bone: cortical tissue density0.30.40.7-0.80.80.8-0.80.60.60.7-0.2-0.1-0.3
Condit. Reinf. active minus inactive responses0.20.20.6-0.40.20.2-0.40.50.50.10.80.70.7
Condit. Reinf. active-inactive response ratio0.10.10.4-0.0-0.0-0.00.00.10.10.00.60.20.3
Condit. Reinf. active responses0.10.10.3-0.30.30.2-0.20.20.20.20.60.60.5
Condit. Reinf. inactive responses0.00.00.20.00.1-0.10.1-0.3-0.3-0.10.20.40.3
Incentive salience index mean0.40.41.0-0.50.40.3-0.60.70.70.20.91.00.9
Condit. Reinf. lever presses0.20.30.6-0.60.60.6-0.50.40.40.80.50.20.3
Condit. Reinf. active minus inactive responses0.60.71.30.6-0.6-0.81.0-1.0-1.0-0.81.10.50.8
Condit. Reinf. active-inactive response ratio1.11.22.41.1-1.0-1.11.5-1.6-1.6-0.70.6-0.00.3
Condit. Reinf. active responses0.70.93.30.1-0.0-0.70.4-0.2-0.2-1.01.81.41.6
Condit. Reinf. inactive responses1.01.23.1-0.50.7-0.2-0.70.90.9-1.01.61.71.8
Condit. Reinf. lever presses1.42.04.0-1.71.81.2-1.11.21.21.02.01.01.3
Condit. Reinf. lever reinforcers received0.60.83.7-0.20.3-0.30.10.10.1-0.61.91.31.6
Conditioned reinforcement - actives0.30.30.80.4-0.4-0.30.9-0.6-0.6-0.1-0.1-0.6-0.5
Conditioned reinforcement - inactives4.95.510.22.8-2.5-2.43.0-3.2-3.2-1.5-0.7-1.5-0.9
Conditioned locomotion6.37.611.13.3-3.3-2.53.3-3.3-3.3-1.4-2.2-2.3-1.9
Patch foraging indifference point 0 sec0.10.10.30.4-0.2-0.40.5-0.2-0.2-0.50.50.10.4
Patch foraging indifference point AUC2.42.85.2-2.32.32.1-1.81.71.71.70.70.60.4
Delay disc. indifference point, 0s delay0.80.92.91.0-1.3-1.30.0-0.1-0.1-1.7-0.21.00.7
Delay disc. indifference point, 16s delay1.21.22.11.2-1.0-1.41.3-1.2-1.2-1.10.90.40.7
Delay disc. indifference point, 2s delay0.20.20.50.5-0.7-0.60.5-0.2-0.2-0.5-0.00.30.3
Delay disc. indifference point, 24s delay0.10.10.30.1-0.2-0.2-0.20.20.2-0.2-0.5-0.2-0.4
Delay disc. indifference point, 4s delay0.40.51.90.5-0.6-0.80.10.20.2-1.40.10.90.6
Delay disc. indifference point, 8s delay0.30.31.10.3-0.3-0.7-0.30.10.1-1.00.00.90.6
Indifference point function ln k5.37.314.93.6-3.9-3.02.7-2.6-2.6-2.3-2.3-1.7-1.4
Indifference point function log k5.37.314.93.6-3.9-3.02.7-2.6-2.6-2.3-2.3-1.7-1.4
Patch foraging total patch changes 0 sec0.00.00.10.2-0.1-0.10.10.00.0-0.1-0.0-0.3-0.1
Patch foraging total patch changes 12 sec3.54.58.1-2.72.82.2-2.32.32.31.51.61.51.3
Patch foraging total patch changes 18 sec0.50.61.4-0.81.20.6-0.40.50.50.21.11.00.9
Patch foraging total patch changes 24 sec1.72.13.7-1.91.71.8-1.71.61.61.50.30.40.1
Patch foraging total patch changes 6 sec1.11.62.6-1.41.60.9-1.31.41.40.41.31.21.2
Patch foraging time to switch 0 sec1.82.87.3-1.51.80.6-1.21.11.10.12.72.42.4
Patch foraging water rate 0 sec3.65.79.22.5-2.7-1.32.4-2.3-2.3-0.4-3.0-3.0-2.8
Patch foraging water rate 12 sec5.99.116.03.5-4.0-2.42.7-2.7-2.7-1.5-3.8-3.0-3.1
Patch foraging water rate 18 sec2.12.85.72.1-2.4-1.61.4-1.6-1.6-1.1-1.9-1.4-1.4
Patch foraging water rate 24 sec3.54.97.82.4-2.6-1.51.9-2.3-2.3-0.8-2.8-2.4-2.4
Patch foraging water rate 6 sec2.63.87.72.1-2.6-1.21.4-1.6-1.6-0.5-2.8-2.1-2.4
Seeking ratio, delayed vs. immediate footshock0.30.31.00.2-0.0-0.6-0.40.00.0-0.60.90.61.0
Distance traveled before self-admin0.20.20.4-0.60.50.5-0.30.30.30.70.50.20.2
Distance traveled after self-admin0.10.10.5-0.40.40.4-0.1-0.2-0.20.70.30.00.1
Extensor digitorum longus weight5.621.935.7-6.05.95.2-5.55.55.54.31.92.31.5
Bone: elastic displacement1.01.14.70.6-0.8-0.00.2-0.3-0.30.5-2.2-1.2-1.9
Bone: elastic work1.51.92.7-1.41.21.6-1.61.71.71.6-1.3-0.2-1.0
Bone: endosteal estimation1.22.74.81.8-1.8-2.11.7-1.5-1.5-2.21.01.21.3
Bone: endosteal perimeter2.04.26.62.1-2.1-2.62.2-2.0-2.0-2.41.71.31.7
Epididymis fat weight2.25.18.52.9-2.7-2.72.9-2.6-2.6-2.4-0.4-0.4-0.1
Delta time in closed arm before/after self-admin0.40.40.9-0.50.50.5-1.00.80.80.2-0.80.3-0.3
Delta time in open arm before/after self-admin0.10.10.5-0.10.20.20.7-0.4-0.40.30.2-0.5-0.2
Diff in mean of infusions in LGA sessions0.40.41.1-0.81.01.0-0.30.40.41.00.3-0.2-0.4
Delay discount exponential model param0.40.41.3-0.40.40.90.0-0.1-0.11.1-0.4-1.0-0.9
Extinction: sum of active levers before priming3.53.55.7-2.22.41.7-1.92.12.11.11.81.61.4
Active lever presses in extinction session 62.12.05.8-1.71.72.0-1.21.21.22.4-0.1-0.4-0.7
Bone: final force1.72.84.6-2.12.01.9-1.91.91.91.51.01.10.8
Bone: final moment1.52.54.0-2.01.91.7-1.71.81.81.40.91.10.7
Food consumed during 24 hour testing period0.20.20.7-0.10.00.40.1-0.2-0.20.80.1-0.8-0.6
Glucose2.23.36.32.1-1.9-2.51.9-1.8-1.8-2.50.80.91.2
Heart weight2.23.15.32.3-2.0-2.22.2-1.9-1.9-2.1-0.4-0.40.0
Delay discount hyperbolic model param0.40.41.1-0.30.40.80.0-0.2-0.21.0-0.4-1.0-0.8
Intermittent access intake day 1-15 change0.80.81.70.6-0.5-0.00.8-1.2-1.20.7-0.3-1.3-1.2
Intermittent access intake escalation0.50.51.30.6-0.5-0.20.7-1.1-1.10.4-0.3-0.9-0.8
Intermittent access intake escalation 20.60.61.50.3-0.30.30.5-0.9-0.90.8-0.7-1.2-1.2
Intermitt. access day 1 inactive lever presses2.02.15.21.7-1.4-1.52.3-1.9-1.9-1.10.1-0.6-0.2
Intermitt. access day 15 inactive lever presses1.81.94.41.6-1.1-1.31.9-2.1-2.1-0.70.3-0.7-0.4
Intermitt. access escalation Index2.82.55.32.1-2.1-2.21.5-1.2-1.2-2.3-0.60.50.4
Intermittent access day 1 total infusions5.66.513.62.9-2.3-3.62.8-2.4-2.4-3.71.11.11.7
Intermittent access day 15 total infusions6.16.811.13.2-2.8-3.23.3-3.3-3.3-2.60.1-0.60.0
Intermittent access terminal intake (last 3 days)4.75.29.32.7-2.2-2.83.0-2.9-2.9-2.40.6-0.20.4
Intermittent access total infusions4.34.78.62.4-1.9-2.92.6-2.4-2.4-2.81.10.71.2
Intermittent access day 1 locomotion3.94.110.32.1-1.6-2.92.0-1.6-1.6-3.20.91.31.8
Intermittent access day 15 total locomotion3.84.16.82.5-2.1-2.52.4-2.6-2.6-2.10.4-0.30.3
Intermittent access total locomotion6.06.812.63.0-2.4-3.62.9-2.9-2.9-3.31.10.71.4
Intermittent access standard deviation0.80.91.81.0-0.9-0.71.1-1.3-1.3-0.3-0.5-0.8-0.8
Left kidney weight0.61.83.21.4-1.4-0.81.7-1.8-1.8-0.1-1.2-1.1-1.2
Right kidney weight0.41.22.50.6-0.70.21.4-1.3-1.31.0-0.8-1.6-1.5
Cocaine induced anxiety0.10.10.3-0.10.20.2-0.0-0.1-0.10.3-0.2-0.6-0.4
Post-drug Anxiety1.21.33.0-1.41.41.6-1.00.80.81.7-0.0-0.7-0.6
Baseline Anxiety1.81.93.7-1.81.61.9-1.41.51.51.80.10.1-0.2
Tail length1.03.16.0-1.71.22.3-1.81.51.52.5-1.7-1.4-1.9
Length with tail1.97.012.3-3.33.03.5-3.02.82.83.4-0.2-0.3-0.9
Length without tail2.04.47.4-2.72.52.5-2.52.52.52.10.80.80.3
Times rat made contact with spout0.60.71.5-0.70.60.3-0.91.21.20.00.91.00.9
Lifetime Intake3.84.38.42.3-1.8-2.82.4-2.1-2.1-2.91.10.91.3
Liver weight, left0.10.20.60.3-0.5-0.20.1-0.2-0.2-0.1-0.7-0.8-0.5
Liver weight, right0.10.10.60.2-0.5-0.2-0.30.30.3-0.3-0.8-0.1-0.3
Locomotor activity1.21.94.91.4-1.8-0.80.9-1.0-1.0-0.5-2.2-1.4-1.8
Locomotor testing distance1.52.56.41.7-2.3-1.20.9-0.9-0.9-0.9-2.5-1.4-1.9
Locomotor testing rearing1.21.93.51.8-1.9-1.71.2-1.2-1.2-1.9-1.1-0.3-0.5
Locomotion in novel chamber3.84.77.52.7-2.7-2.32.5-2.7-2.7-1.5-1.0-1.4-0.9
Locomotion in novel chamber post-restriction2.32.85.32.0-2.2-1.82.3-1.8-1.8-1.2-0.9-1.0-0.7
Fecal boli incidents, locomotor time 10.20.20.6-0.10.50.40.5-0.6-0.60.40.8-0.3-0.1
Change in fecal boli incidents, locomotor task0.30.30.9-0.0-0.2-0.4-0.90.50.5-0.80.00.80.6
Time >=10cm from walls, locomotor time 11.81.83.01.2-0.7-1.60.9-1.5-1.5-1.71.50.91.5
Bouts of movement, locomotor time 10.90.91.8-1.21.31.2-0.90.60.61.31.20.20.2
Total resting periods, locomotor time 10.60.61.7-1.01.10.9-0.60.40.41.01.30.20.4
Rest time, locomotor task time 11.21.32.21.3-1.5-0.91.4-1.2-1.2-0.1-0.9-1.3-1.0
Distance moved, locomotor task time 10.40.51.5-0.30.5-0.2-0.60.50.5-0.60.61.21.2
Vertical activity count, locomotor time 10.70.71.11.1-0.9-0.90.8-1.1-1.1-0.9-0.4-0.4-0.4
Time >=10cm from walls, locomotor time 20.10.10.20.1-0.1-0.20.2-0.4-0.4-0.10.30.00.2
Bouts of movement, locomotor time 20.40.41.0-0.81.00.7-0.80.60.60.40.60.50.5
Total resting periods, locomotor time 20.20.20.5-0.60.70.3-0.40.30.30.20.70.60.6
Rest time, locomotor task time 21.82.13.51.8-1.8-1.61.6-1.9-1.9-1.1-0.6-0.5-0.5
Distance moved, locomotor task time 21.01.22.0-1.31.21.2-1.41.41.41.10.10.20.1
Vertical activity count, locomotor time 20.70.82.2-0.40.00.8-0.70.40.40.9-1.4-1.2-1.5
Light reinforcement 10.10.20.40.6-0.6-0.40.4-0.2-0.2-0.4-0.5-0.5-0.4
Light reinforcement 21.01.32.81.3-1.4-0.91.7-1.3-1.3-0.0-0.1-1.3-0.8
Bone: marrow area1.32.85.11.8-1.8-2.21.7-1.5-1.5-2.20.91.21.3
Bone: maximum diameter0.10.10.5-0.30.10.40.2-0.2-0.20.70.4-0.1-0.2
Bone: maximum force2.23.86.0-2.22.21.5-1.61.91.90.92.42.32.1
Bone: maximum moment1.93.35.1-2.02.01.3-1.51.91.90.82.22.21.9
Mean time between licks in bursts0.60.92.3-0.80.30.7-1.41.51.50.4-0.50.4-0.1
Mean num. licks in bursts0.10.20.60.5-0.4-0.60.2-0.2-0.2-0.8-0.00.20.2
Cd content in liver1.41.63.41.3-1.2-0.81.5-1.8-1.8-0.4-0.8-0.9-1.1
Co content in liver1.31.66.21.0-1.2-0.40.3-0.7-0.7-0.4-2.5-1.6-1.8
Cu content in liver0.20.30.4-0.60.60.3-0.60.70.70.20.50.30.6
Fe content in liver0.10.20.4-0.40.40.6-0.20.40.40.7-0.2-0.4-0.3
K content in liver1.81.73.4-1.31.40.6-1.21.41.40.21.81.51.7
Mg content in liver1.81.85.7-0.00.2-0.9-0.10.40.4-1.42.22.12.4
Mn content in liver1.82.14.3-1.82.11.5-1.01.41.41.31.60.80.8
Na content in liver0.91.02.8-1.10.71.3-0.81.01.01.7-0.2-0.7-0.6
Rb content in liver1.51.95.31.5-1.3-2.01.1-1.1-1.1-2.30.61.01.1
Se content in liver0.60.72.00.10.1-0.50.8-0.7-0.7-0.41.41.31.0
Sr content in liver2.52.24.4-1.81.92.1-1.41.41.42.1-0.2-0.7-0.7
Zn content in liver0.91.01.9-1.21.40.9-1.11.11.10.70.91.10.7
Bone: minimum diameter1.42.75.01.4-1.2-2.01.6-1.1-1.1-2.21.61.71.9
Time in familiar zone, hab. session 10.30.30.60.6-0.6-0.80.5-0.3-0.3-0.70.60.10.6
Time in novel zone, hab. session 10.30.31.70.3-0.50.1-0.1-0.2-0.20.0-1.3-0.5-1.0
Total zone transitions, hab. session 10.60.81.2-1.10.90.8-1.11.01.00.70.60.80.6
Total locomotion distance, hab. session 10.30.40.70.7-0.8-0.70.5-0.8-0.8-0.6-0.00.20.2
Locomotion velocity, hab. session 10.10.10.20.2-0.3-0.30.1-0.3-0.3-0.20.20.50.3
Time in familiar zone, hab. session 20.30.31.0-0.20.10.4-0.70.60.60.1-1.0-0.5-0.7
Time in novel zone, hab. session 20.40.41.30.00.1-0.40.3-0.1-0.1-0.41.10.91.0
Total zone transitions, hab. session 22.63.310.7-0.90.9-0.2-1.11.31.3-1.12.63.32.9
Total locomotion distance, hab. session 20.81.13.40.4-0.3-0.90.1-0.1-0.1-1.41.31.91.7
Locomotion velocity, hab. session 20.91.23.00.6-0.5-1.10.4-0.5-0.5-1.41.31.71.6
Novel to familiar place preference ratio0.60.62.4-0.81.00.5-0.10.30.30.51.50.51.0
Novelty place preference0.40.42.0-0.40.60.10.20.00.00.21.40.40.9
Time in novel zone, NPP test0.30.31.6-0.30.50.00.20.00.00.11.30.40.9
Total zone transitions, NPP test1.52.13.3-1.61.31.0-1.61.61.60.51.41.81.5
Total locomotion distance, NPP test0.10.21.1-0.1-0.2-0.1-0.30.10.1-0.30.41.10.7
Locomotion velocity, NPP test0.10.20.9-0.1-0.1-0.0-0.30.10.1-0.10.40.90.6
Intraocular pressure1.31.83.91.0-0.4-0.31.8-2.0-2.00.3-0.7-1.9-1.4
Delta distance traveled before/after self-admin0.00.00.10.00.10.00.1-0.2-0.20.1-0.3-0.2-0.2
Delta ambulatory time before/after self-admin0.00.00.2-0.10.10.2-0.20.10.10.2-0.4-0.1-0.2
Parametrial fat weight2.34.47.22.5-2.2-2.52.7-2.5-2.5-2.50.50.60.7
Pavlov. Cond. lever latency0.10.20.30.4-0.5-0.30.3-0.5-0.5-0.1-0.5-0.5-0.5
Pavlov. Cond. magazine entry latency0.50.72.50.00.1-0.50.2-0.1-0.1-0.61.61.21.4
Pavlov. Cond. change in total contacts0.20.31.40.1-0.0-0.20.6-0.4-0.4-0.01.20.20.6
Pavlov. Cond. index score0.00.10.3-0.20.20.10.10.00.00.20.60.00.3
Pavlov. Cond. latency score0.00.10.3-0.00.1-0.10.10.00.0-0.10.50.20.4
Pavlov. Cond. lever contacts0.00.00.0-0.00.1-0.0-0.10.20.2-0.00.20.10.2
Pavlov. Cond. magazine entry number0.10.10.40.3-0.4-0.4-0.10.10.1-0.6-0.60.4-0.0
Pavlov. Cond. intertrial magazine entries0.20.30.60.4-0.5-0.10.7-0.6-0.60.1-0.5-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.40.40.3-0.10.20.20.30.70.20.4
Pavlov. Cond. response bias0.00.10.2-0.20.20.20.1-0.0-0.00.40.4-0.30.0
Pavlov. Cond. lever latency0.30.41.00.8-0.9-0.60.3-0.3-0.3-0.7-1.0-0.3-0.5
Pavlov. Cond. magazine entry latency2.93.34.5-2.12.11.4-1.91.91.91.02.11.71.6
Pavlov. Cond. change in total contacts1.21.75.9-1.41.50.9-0.60.60.60.92.41.31.5
Pavlov. Cond. index score1.62.04.0-1.71.81.3-1.21.21.21.22.01.21.3
Pavlov. Cond. latency score1.31.63.2-1.61.61.1-1.11.01.01.21.81.01.1
Pavlov. Cond. lever contacts0.30.41.0-0.80.80.8-0.40.30.31.00.6-0.20.0
Pavlov. Cond. magazine entry number4.55.58.12.8-2.8-2.12.4-2.4-2.4-1.6-2.7-2.0-1.9
Pavlov. Cond. intertrial magazine entries1.01.31.91.4-1.3-1.11.4-1.4-1.4-0.8-0.8-0.8-0.7
Pavlov. Cond. lever-magazine prob. diff.2.02.54.3-1.92.01.4-1.41.41.41.32.11.31.4
Pavlov. Cond. response bias1.11.42.5-1.61.61.2-1.11.01.01.11.50.70.9
Time in closed arm before self-admin0.10.10.50.1-0.2-0.20.5-0.1-0.1-0.20.70.10.4
Time in closed arm after self-admin0.00.00.1-0.0-0.0-0.1-0.20.30.3-0.00.00.20.2
Time in open arm before self-admin0.20.31.00.5-0.6-0.5-0.4-0.0-0.0-0.6-1.00.1-0.3
Time in open arm after self-admin0.30.30.80.3-0.3-0.10.6-0.4-0.40.0-0.9-0.8-0.8
Bone: periosteal estimation0.10.20.30.2-0.2-0.30.5-0.4-0.4-0.20.50.50.4
Bone: periosteal perimeter0.20.31.3-0.10.1-0.20.2-0.0-0.0-0.21.10.90.9
Bone: post-yield work3.85.218.30.20.2-1.50.8-0.5-0.5-1.94.33.44.0
Progressive ratio test 1 active lever presses2.12.23.71.8-1.6-1.91.9-1.8-1.8-1.5-0.2-0.40.0
Progressive ratio test 1 breakpoint1.81.93.31.7-1.5-1.71.8-1.7-1.7-1.3-0.3-0.5-0.1
Progressive ratio test 1 inactive lever presses0.91.01.91.2-1.0-1.41.1-1.1-1.1-1.20.10.00.3
Progressive ratio test 2 active lever presses3.33.56.02.2-1.9-2.42.4-2.4-2.4-1.90.3-0.40.1
Progressive ratio test 2 breakpoint3.84.37.22.5-2.3-2.42.7-2.6-2.6-1.8-0.3-0.9-0.5
Progressive ratio test 2 inactive lever presses7.08.112.93.5-3.1-3.63.3-3.5-3.5-3.10.1-0.40.2
Incentive Sensitization - Responses0.50.51.00.6-0.4-0.81.0-0.8-0.8-0.80.80.30.4
Incentive Sensitization - Breakpoint0.60.61.40.8-0.6-0.91.2-1.0-1.0-0.80.70.10.2
Sum of active levers in priming session hrs 5-62.01.96.6-1.41.42.0-0.70.40.42.6-0.3-1.4-1.4
Progressive ratio2.32.76.1-1.21.50.2-1.11.41.4-0.52.42.42.5
Food seeking constrained by brief footshock0.40.51.4-0.70.80.6-1.20.80.80.8-0.20.1-0.1
Seeking ratio, punishment vs. effort1.51.85.31.1-1.4-0.30.4-0.9-0.90.3-2.3-1.8-2.1
Retroperitoneal fat weight4.113.321.54.6-4.5-4.34.5-4.3-4.3-3.6-0.9-1.0-0.4
Reaction time number correct0.50.71.5-0.80.71.0-0.60.90.91.2-0.5-0.4-0.8
Reaction time mean minus median1.82.45.4-2.12.31.8-1.31.21.21.61.70.70.9
Reaction time mean minus median AUC1.21.63.1-1.71.81.7-1.21.11.11.70.6-0.1-0.1
Reaction time num false alarms0.50.63.10.1-0.40.2-0.40.50.50.3-1.8-0.9-1.1
Reaction time num false alarms AUC0.60.91.9-0.60.40.8-1.11.11.10.8-1.4-0.6-0.9
Reaction time trials correct on left0.50.71.5-0.80.71.0-0.60.90.91.2-0.5-0.4-0.8
Reaction time trials on left0.60.91.9-0.90.81.2-0.71.01.01.4-0.6-0.4-0.9
Reaction time mean0.10.10.2-0.10.20.00.1-0.5-0.50.20.4-0.40.1
Reaction time mean AUC0.10.10.30.00.1-0.10.3-0.6-0.60.10.6-0.40.2
Median of all reaction times0.20.20.70.4-0.3-0.50.5-0.8-0.8-0.30.2-0.40.1
Reaction time omissions1.11.52.9-1.61.71.5-1.31.21.21.50.40.10.1
Reaction time false alarm rate0.20.31.40.1-0.30.1-0.40.30.30.1-1.2-0.6-0.6
Reaction time premature initiation rate2.02.75.5-1.91.51.8-2.32.32.31.4-0.3-0.0-0.1
Reaction time premature initiations3.54.98.8-2.62.12.6-2.83.03.02.3-0.5-0.3-0.6
Std. dev. reaction times0.40.61.8-1.11.31.0-0.50.30.30.91.00.00.3
Reaction time trials completed0.60.91.9-0.90.81.2-0.71.01.01.4-0.6-0.4-0.9
Reaction time trials AUC0.40.61.2-0.70.60.9-0.60.90.91.1-0.6-0.4-0.8
Run reversals in cocaine runway, females1.21.22.7-0.60.60.0-1.51.11.1-0.91.01.61.5
Run reversals in cocaine runway, males1.51.54.50.0-0.00.70.0-0.3-0.31.1-2.1-1.9-2.1
Latency to leave start box in cocaine runway0.50.51.40.2-0.2-0.60.7-0.2-0.2-0.71.10.91.2
Latency to leave start box in cocaine runway, F0.20.20.70.0-0.2-0.30.4-0.0-0.0-0.50.80.70.8
Latency to leave start box in cocaine runway, M0.00.00.1-0.00.1-0.10.20.00.00.00.20.10.2
Std. dev. time between licks in bursts0.50.63.4-0.1-0.20.4-0.60.50.50.2-1.9-0.7-1.1
Total sessions with >9 infusions1.41.53.41.4-1.2-1.71.4-1.1-1.1-1.80.40.40.8
Short access day 1 total inactive lever presses3.13.56.02.3-2.2-2.22.5-2.1-2.1-2.2-0.5-0.20.0
Short access day 10 total inactive lever presses2.12.33.81.9-1.8-1.61.9-1.7-1.7-1.3-0.8-0.8-0.7
Short access day 1 total infusions3.43.68.12.1-1.8-2.62.3-1.6-1.6-2.80.81.01.3
Short access day 10 total infusions3.13.58.31.4-0.9-2.41.3-0.9-0.9-2.92.02.22.5
Short access total infusions1.92.15.81.3-1.0-2.01.4-0.9-0.9-2.41.01.31.5
Short access day 1 locomotion2.52.76.41.7-1.2-2.31.5-1.5-1.5-2.51.21.11.4
Short access day 10 total locomotion1.71.94.61.4-1.0-2.01.0-1.0-1.0-2.10.91.31.5
Short access total locomotion1.71.84.91.3-0.9-1.91.1-0.8-0.8-2.20.91.11.5
One hour access (0.3 mA shock)7.28.413.53.6-3.2-3.43.5-3.7-3.7-2.8-0.4-1.1-0.5
Compulsive drug intake2.62.75.4-1.91.61.9-2.32.02.01.5-0.80.3-0.3
One hour access (shock baseline)7.18.214.83.5-3.0-3.23.9-3.7-3.7-2.50.2-1.1-0.3
Social response proportion0.60.72.0-0.80.80.5-0.60.70.70.31.40.91.0
Social responses0.20.30.5-0.70.70.6-0.60.50.50.40.30.10.1
Social time0.30.40.9-0.70.60.7-1.00.60.60.5-0.1-0.0-0.2
Soleus weight3.19.015.73.7-4.0-3.03.2-3.6-3.6-2.0-2.3-1.8-1.7
Bone: stiffness1.82.86.5-1.71.81.0-1.11.51.50.42.52.02.1
Tibialis anterior weight8.127.846.0-6.86.56.7-6.16.06.06.10.70.6-0.2
Time to tail flick, vehicle, before self-admin0.50.50.8-0.60.70.2-0.90.80.80.00.80.90.9
Time to tail flick, vehicle, after self-admin1.41.52.5-1.21.40.7-1.61.51.50.00.91.41.2
Time to tail flick, test, before self-admin1.00.92.90.8-0.8-1.30.2-0.3-0.3-1.70.31.41.1
Time to tail flick, test, after self-admin0.00.00.2-0.10.10.1-0.4-0.0-0.00.0-0.1-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.50.50.8-0.70.80.4-0.70.70.7-0.00.70.90.7
Delta time to tail flick, test, before/after SA2.01.84.2-1.21.31.8-1.00.70.72.0-0.7-1.7-1.5
Tibia length0.71.96.6-1.81.62.1-0.90.70.72.60.1-0.3-0.7
Ambulatory time before self-admin0.20.20.8-0.50.60.40.0-0.0-0.00.70.90.00.3
Ambulatory time after self-admin0.50.51.00.5-0.1-0.70.8-1.0-1.0-0.21.00.30.8
Bone: tissue strength0.20.10.60.0-0.1-0.10.2-0.2-0.2-0.10.80.60.5
Total heroin consumption3.74.47.4-2.72.72.4-2.02.52.52.11.11.20.6
Bone: trabecular number1.32.17.3-0.61.0-0.2-0.20.30.3-0.82.72.42.4
Bone: trabecular spacing0.30.41.40.5-0.7-0.30.1-0.0-0.0-0.0-1.2-0.8-0.8
Bone: trabecular thickness1.01.22.30.8-0.7-1.30.8-0.7-0.7-1.51.41.31.4
Bone: trabecular tissue density2.83.96.12.4-2.5-1.62.4-2.4-2.4-0.9-1.5-1.2-1.6
Water consumed over 24 hours0.60.81.5-1.01.00.8-1.01.21.20.40.70.50.5
Number of responses in last shaping day0.70.81.51.1-1.0-1.01.2-0.7-0.7-0.8-0.8-0.6-0.6