Hub : Genes

Slc29a2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Slc29a2 0.34 0.11 0.0e+00 0.13 0.15 0.14 0.14 6.4e-14 5.8e-16 5.0e-15 2.1e-15
2 PL gene expression Slc29a2 0.48 0.16 0.0e+00 0.27 0.3 0.29 0.3 1.3e-29 5.5e-33 1.2e-31 1.6e-32
3 BLA gene expression Slc29a2 0.51 0.15 4.7e-12 0.23 0.22 0.21 0.22 1.5e-12 1.2e-11 2.5e-11 4.5e-12
4 NAcc gene expression Slc29a2 0.06 0.04 3.2e-09 0.06 0.06 0.06 0.06 5.2e-09 1.3e-09 8.5e-10 1.4e-09
5 Brain gene expression Slc29a2 0.05 0.03 9.4e-06 0.03 0.04 0.04 0.03 1.2e-03 5.2e-05 1.5e-04 5.8e-04
6 IL gene expression Slc29a2 0.16 0.12 5.2e-03 0.11 0.09 0.07 0.07 1.2e-03 3.4e-03 1.0e-02 8.9e-03
7 LHb alternative polyA XM_008760174.4 0.13 0.09 6.6e-03 0.12 0.04 0.07 0.01 1.1e-03 4.2e-02 7.9e-03 2.1e-01
8 OFC gene expression Slc29a2 0.19 0.12 1.2e-03 0.04 0.04 0.03 0.01 3.7e-02 4.2e-02 8.0e-02 1.9e-01
9 IC gene expression Slc29a2 0.24 0.17 8.2e-05 0.04 0.08 0.09 0.09 5.9e-03 3.1e-04 1.3e-04 1.4e-04
10 Adipose alternative polyA NM_031738.1 0.03 0.02 4.3e-03 0.01 0.01 0 0.01 1.1e-02 4.1e-02 1.1e-01 6.3e-02
11 Adipose alternative polyA XM_008760174.4 0.03 0.02 3.8e-03 0.01 0.01 0 0.01 9.2e-03 2.8e-02 8.5e-02 5.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.91.73.9-1.1-1.30.61.60.30.80.9-1.01.72.0-2.0
Area under the delay curve0.40.51.5-0.0-0.30.20.40.80.20.5-1.21.20.9-0.9
BMI with tail2.48.316.3-3.3-3.12.23.6-0.52.50.4-1.13.64.0-4.0
BMI without tail0.84.510.6-2.6-2.42.12.6-0.41.7-0.3-1.03.32.4-2.4
Body weight2.410.417.8-4.2-4.03.83.8-2.63.7-2.21.13.82.3-2.3
Weight adjusted by age0.61.72.8-1.5-1.31.71.5-1.71.6-1.51.50.6-0.10.1
Bone surface2.75.39.3-2.7-2.92.13.1-1.72.4-0.40.62.02.8-2.8
Bone volume1.12.14.7-1.5-1.70.92.2-0.61.20.4-0.11.32.1-2.1
Breakpoint value in progressive ratio session1.22.23.9-2.0-1.81.71.7-1.91.7-1.11.50.70.6-0.6
Number of licking bursts0.10.30.6-0.5-0.70.50.7-0.60.7-0.30.70.10.6-0.6
Context. condit. distance diff. score1.41.72.51.41.6-1.5-1.51.5-1.41.2-1.5-0.9-0.70.7
Locomotion velocity, session 10.20.20.9-0.1-0.20.40.7-0.20.0-0.90.10.7-0.30.3
Locomotion distance, session 11.11.33.5-1.1-1.21.01.30.10.70.0-0.81.91.5-1.5
Locomotion velocity, session 22.52.94.7-2.1-2.02.02.2-1.42.0-1.40.82.01.1-1.1
Locomotion distance, session 21.41.95.9-1.5-1.61.41.7-0.41.2-0.7-0.42.41.3-1.3
Locomotion velocity, session 30.30.30.70.10.1-0.20.70.7-0.00.5-0.70.50.8-0.8
Locomotion distance, session 30.10.10.60.1-0.10.10.80.10.2-0.1-0.00.20.4-0.4
Stereotopy head waving bouts, day 30.50.62.20.50.5-0.60.21.4-0.50.9-1.50.60.6-0.6
Stereotopy head waving duration, day 30.81.02.30.90.8-1.1-0.61.5-1.01.4-1.4-0.10.4-0.4
Locomotion velocity, session 70.50.51.9-0.20.2-0.40.50.9-0.30.9-1.40.50.9-0.9
Locomotion distance, session 70.30.41.3-0.7-0.50.50.70.30.6-0.2-0.81.10.3-0.3
Stereotopy head waving bouts, day 70.60.61.60.40.4-0.80.60.6-0.61.1-0.6-0.51.3-1.3
Stereotopy head waving duration, day 70.70.93.3-0.7-0.70.11.4-0.20.20.60.00.31.8-1.8
Locomotion velocity, session 81.01.21.8-1.1-1.31.31.0-1.11.2-1.30.91.20.1-0.1
Locomotion distance, session 80.20.31.20.30.5-0.5-0.40.8-0.50.6-1.10.10.1-0.1
Degree of sensitization distance0.20.30.7-0.6-0.40.30.40.30.20.2-0.80.80.5-0.5
Degree of sensitization stereotypy0.40.41.4-0.4-0.3-0.21.0-0.40.00.40.2-0.41.2-1.2
Conditioned locomotion1.61.83.2-1.8-1.51.81.1-1.61.6-1.70.91.3-0.20.2
Cocaine response after cond. corrected0.60.91.61.01.3-0.9-1.21.0-0.90.5-1.0-0.5-0.80.8
Cocaine response after cond. not corrected0.40.61.21.01.1-0.9-1.00.9-0.80.7-0.7-0.6-0.40.4
Cocaine response before conditioning0.40.51.2-0.5-0.80.50.9-0.80.7-0.11.1-0.10.8-0.8
Saline control response2.94.06.9-2.3-2.62.52.2-1.92.5-1.51.32.01.2-1.2
Bone: connectivity density2.33.66.1-2.2-2.41.72.2-0.81.70.1-0.42.32.5-2.5
Bone: cortical apparent density0.10.20.5-0.4-0.30.50.0-0.7-0.1-0.70.60.0-0.40.4
Bone: cortical area0.50.81.8-0.9-0.80.90.4-1.31.3-1.11.20.0-0.50.5
Bone: cortical porosity0.30.31.0-0.5-0.60.50.70.20.50.2-0.31.00.6-0.6
Bone: cortical porosity0.50.61.8-0.9-1.00.90.9-0.20.9-0.2-0.01.30.4-0.4
Bone: cortical thickness3.25.410.2-2.3-2.22.61.5-3.13.0-3.22.90.8-0.90.9
Bone: cortical thickness1.41.73.8-1.2-1.31.61.1-1.41.6-2.01.41.1-0.30.3
Bone: cortical tissue density0.20.30.8-0.5-0.50.60.2-0.80.1-0.90.80.2-0.40.4
Condit. Reinf. active minus inactive responses0.40.41.3-0.5-0.40.51.1-0.20.3-0.3-0.20.70.9-0.9
Condit. Reinf. active-inactive response ratio0.10.10.3-0.00.10.10.6-0.10.1-0.0-0.20.20.6-0.6
Condit. Reinf. active responses0.10.20.4-0.5-0.20.40.6-0.20.0-0.3-0.40.60.5-0.5
Condit. Reinf. inactive responses0.10.10.4-0.20.1-0.1-0.00.2-0.50.1-0.60.20.1-0.1
Incentive salience index mean0.40.51.0-0.9-0.70.71.0-0.30.5-0.3-0.41.00.8-0.8
Condit. Reinf. lever presses0.20.20.7-0.8-0.50.60.2-0.70.5-0.50.10.30.1-0.1
Condit. Reinf. active minus inactive responses0.40.71.60.80.5-1.00.10.6-0.81.3-0.3-1.01.0-1.0
Condit. Reinf. active-inactive response ratio0.91.52.71.41.3-1.6-0.71.0-1.61.5-0.6-1.60.4-0.4
Condit. Reinf. active responses0.60.93.3-0.0-0.4-0.31.00.40.11.2-0.3-0.01.8-1.8
Condit. Reinf. inactive responses1.11.63.0-1.2-1.40.91.6-0.11.40.3-0.11.61.7-1.7
Condit. Reinf. lever presses1.21.84.2-1.3-1.61.02.0-1.21.3-0.41.00.51.7-1.7
Condit. Reinf. lever reinforcers received0.60.93.3-0.3-0.6-0.01.20.10.40.90.00.01.8-1.8
Conditioned reinforcement - actives0.10.31.30.50.3-0.5-0.2-0.3-0.40.10.8-1.2-0.60.6
Conditioned reinforcement - inactives1.23.26.02.52.3-2.3-1.61.6-2.31.6-0.9-2.0-0.40.4
Conditioned locomotion5.58.214.23.83.5-3.4-3.52.7-3.32.2-1.6-2.8-1.81.8
Patch foraging indifference point 0 sec0.10.20.70.40.2-0.3-0.40.50.10.8-0.4-0.30.4-0.4
Patch foraging indifference point AUC0.71.73.8-1.7-1.51.31.5-2.01.2-1.31.60.20.4-0.4
Delay disc. indifference point, 0s delay0.70.83.30.30.1-0.1-0.31.4-0.20.6-1.81.50.4-0.4
Delay disc. indifference point, 16s delay0.60.81.71.00.8-1.0-0.31.2-0.91.3-1.1-0.50.7-0.7
Delay disc. indifference point, 2s delay0.20.20.50.50.2-0.4-0.30.7-0.10.6-0.70.10.4-0.4
Delay disc. indifference point, 24s delay0.10.20.4-0.0-0.20.4-0.20.10.5-0.5-0.20.6-0.50.5
Delay disc. indifference point, 4s delay0.50.52.3-0.1-0.30.3-0.00.80.30.3-1.31.50.4-0.4
Delay disc. indifference point, 8s delay0.20.41.6-0.1-0.40.30.20.60.10.2-1.01.30.5-0.5
Indifference point function ln k2.16.311.03.33.3-2.7-3.03.1-2.31.8-2.2-1.3-1.81.8
Indifference point function log k2.16.311.03.33.3-2.7-3.03.1-2.31.8-2.2-1.3-1.81.8
Patch foraging total patch changes 0 sec0.00.00.10.20.10.0-0.30.10.30.2-0.0-0.2-0.10.1
Patch foraging total patch changes 12 sec2.83.77.4-2.7-2.62.22.2-2.12.1-1.21.31.31.3-1.3
Patch foraging total patch changes 18 sec0.30.61.1-1.0-0.90.71.1-0.60.8-0.00.40.51.0-1.0
Patch foraging total patch changes 24 sec0.51.63.0-1.6-1.61.61.3-1.71.4-1.31.40.40.2-0.2
Patch foraging total patch changes 6 sec1.01.63.5-1.5-1.51.31.9-1.01.4-0.50.51.01.3-1.3
Patch foraging time to switch 0 sec0.72.55.2-2.0-1.91.41.7-0.70.90.1-0.21.92.3-2.3
Patch foraging water rate 0 sec1.66.110.03.13.1-2.4-3.21.5-2.10.6-0.4-2.8-2.92.9
Patch foraging water rate 12 sec2.28.816.83.93.6-2.8-4.12.6-2.61.0-1.4-2.1-3.43.4
Patch foraging water rate 18 sec1.12.34.52.12.0-1.4-1.91.6-1.30.6-0.9-1.0-1.71.7
Patch foraging water rate 24 sec3.54.98.12.72.8-2.0-2.91.6-2.20.5-0.8-1.9-2.72.7
Patch foraging water rate 6 sec2.84.18.02.62.5-1.6-2.81.5-1.3-0.1-0.6-1.2-2.82.8
Seeking ratio, delayed vs. immediate footshock0.30.51.10.1-0.10.3-0.10.7-0.10.6-1.11.01.0-1.0
Distance traveled before self-admin0.20.41.5-0.5-0.70.10.7-0.30.50.40.00.01.2-1.2
Distance traveled after self-admin0.10.20.7-0.2-0.3-0.10.7-0.4-0.30.00.2-0.40.9-0.9
Extensor digitorum longus weight5.722.837.4-6.1-5.65.85.4-5.45.6-4.93.73.91.6-1.6
Bone: elastic displacement0.70.92.80.70.8-0.2-1.1-0.1-0.5-1.00.2-0.6-1.71.7
Bone: elastic work1.41.84.5-1.4-1.31.70.7-1.71.6-2.11.20.9-0.40.4
Bone: endosteal estimation0.92.25.71.21.2-1.5-0.82.1-1.42.1-2.40.00.8-0.8
Bone: endosteal perimeter1.53.67.91.81.7-2.3-0.52.4-1.92.8-2.4-0.91.5-1.5
Epididymis fat weight2.311.517.44.14.1-4.2-4.13.3-3.83.2-2.4-3.5-1.61.6
Delta time in closed arm before/after self-admin0.90.82.1-1.1-1.01.30.8-0.51.1-1.1-0.01.5-0.20.2
Delta time in open arm before/after self-admin0.20.31.00.10.1-0.50.6-0.5-0.50.20.7-1.00.2-0.2
Diff in mean of infusions in LGA sessions0.20.41.2-0.9-0.80.50.1-1.10.5-0.50.9-0.1-0.40.4
Delay discount exponential model param0.30.41.40.10.4-0.3-0.4-0.6-0.2-0.31.0-1.2-0.80.8
Extinction: sum of active levers before priming1.01.63.5-1.9-1.71.41.4-1.21.6-0.40.71.00.8-0.8
Active lever presses in extinction session 61.81.83.6-1.5-1.31.41.6-1.91.3-1.21.90.00.7-0.7
Bone: final force1.52.43.7-1.9-1.91.81.9-1.71.8-1.41.01.40.8-0.8
Bone: final moment1.42.33.5-1.9-1.91.81.7-1.61.8-1.41.01.40.7-0.7
Food consumed during 24 hour testing period0.20.41.40.50.3-0.3-0.3-0.5-0.1-0.21.1-1.2-0.60.6
Glucose2.13.47.91.71.6-2.0-1.02.7-1.82.4-2.80.31.1-1.1
Heart weight1.22.07.70.50.4-0.7-0.42.2-0.81.8-2.81.31.2-1.2
Delay discount hyperbolic model param0.30.41.30.00.3-0.2-0.4-0.7-0.2-0.41.0-1.1-0.80.8
Intermittent access intake day 1-15 change0.42.03.61.81.8-1.5-1.60.8-1.90.8-0.3-1.9-0.90.9
Intermittent access intake escalation0.31.84.01.71.7-1.5-1.40.6-1.80.6-0.1-2.0-0.90.9
Intermittent access intake escalation 21.22.04.51.71.8-1.7-1.50.6-1.80.7-0.1-2.1-1.01.0
Intermitt. access day 1 inactive lever presses0.00.30.70.60.7-0.8-0.20.2-0.80.3-0.1-0.80.1-0.1
Intermitt. access day 15 inactive lever presses0.41.93.91.71.7-1.9-0.71.3-2.01.4-1.0-1.50.6-0.6
Intermitt. access escalation Index0.92.85.31.91.7-1.8-1.82.3-1.51.7-2.2-0.4-1.11.1
Intermittent access day 1 total infusions1.13.48.11.61.3-2.0-0.82.7-1.72.8-2.8-0.01.2-1.2
Intermittent access day 15 total infusions2.25.58.92.92.7-3.0-2.12.5-3.02.6-2.0-2.2-0.30.3
Intermittent access terminal intake (last 3 days)2.84.98.92.62.4-3.0-1.52.5-2.82.7-2.1-1.90.4-0.4
Intermittent access total infusions2.83.36.42.01.7-2.2-1.02.4-2.02.5-2.3-0.90.7-0.7
Intermittent access day 1 locomotion1.22.24.51.31.2-1.6-0.52.1-1.52.1-2.1-0.11.2-1.2
Intermittent access day 15 total locomotion1.24.67.42.72.5-2.6-1.72.4-2.72.6-1.9-1.90.2-0.2
Intermittent access total locomotion5.76.811.03.12.9-3.2-1.93.2-3.23.3-2.8-1.80.7-0.7
Intermittent access standard deviation0.21.32.61.61.6-1.4-1.11.0-1.60.6-0.5-1.3-0.40.4
Left kidney weight0.43.46.81.92.1-1.9-2.62.0-2.21.5-2.0-1.1-1.31.3
Right kidney weight0.42.67.51.71.7-1.4-2.71.0-1.50.7-0.5-1.4-1.91.9
Cocaine induced anxiety0.00.10.4-0.00.0-0.10.5-0.2-0.4-0.00.3-0.30.6-0.6
Post-drug Anxiety0.40.40.8-0.7-0.80.50.8-0.90.4-0.40.9-0.10.6-0.6
Baseline Anxiety0.20.30.7-0.6-0.80.5-0.0-0.70.9-0.50.70.2-0.40.4
Tail length0.42.25.8-1.4-1.31.90.6-1.81.2-2.41.41.3-1.21.2
Length with tail1.56.912.1-3.0-2.83.32.0-3.33.1-3.52.62.0-0.50.5
Length without tail1.15.910.1-2.6-2.62.92.3-2.93.2-3.02.71.7-0.10.1
Times rat made contact with spout0.70.91.9-1.0-1.11.11.0-0.41.2-0.4-0.01.40.8-0.8
Lifetime Intake1.82.24.61.51.3-1.8-0.82.1-1.52.1-2.1-0.40.6-0.6
Liver weight, left0.61.02.20.91.0-0.7-1.50.8-1.0-0.0-0.7-0.1-1.51.5
Liver weight, right0.91.62.91.61.5-1.1-1.71.7-1.00.5-1.30.1-1.21.2
Locomotor activity0.91.42.81.61.3-0.8-1.51.0-1.1-0.2-0.4-0.6-1.71.7
Locomotor testing distance0.71.63.21.81.4-0.9-1.51.2-1.1-0.2-0.7-0.3-1.81.8
Locomotor testing rearing0.41.43.21.71.2-1.3-1.21.8-1.20.8-1.40.1-0.50.5
Locomotion in novel chamber4.15.59.43.12.8-2.9-2.72.5-2.92.1-1.8-1.9-0.90.9
Locomotion in novel chamber post-restriction1.13.45.92.32.1-2.4-1.91.9-2.31.8-1.4-1.7-0.70.7
Fecal boli incidents, locomotor time 10.10.42.30.30.5-0.70.5-0.2-0.40.40.6-1.50.3-0.3
Change in fecal boli incidents, locomotor task0.30.31.7-0.3-0.50.7-0.20.40.30.0-0.71.30.1-0.1
Time >=10cm from walls, locomotor time 11.31.63.51.11.0-1.00.11.5-1.41.9-1.5-0.51.4-1.4
Bouts of movement, locomotor time 10.60.81.8-1.0-0.91.11.2-1.30.3-0.81.20.10.4-0.4
Total resting periods, locomotor time 10.40.51.1-0.7-0.60.71.1-1.00.2-0.40.9-0.20.6-0.6
Rest time, locomotor task time 11.11.83.61.91.7-1.7-1.31.1-1.70.8-0.3-1.5-0.80.8
Distance moved, locomotor task time 10.20.71.5-0.7-0.70.50.90.20.60.3-0.71.21.2-1.2
Vertical activity count, locomotor time 10.10.40.80.70.7-0.5-0.90.8-0.50.5-0.6-0.1-0.50.5
Time >=10cm from walls, locomotor time 20.00.10.50.30.3-0.3-0.00.0-0.40.30.1-0.70.2-0.2
Bouts of movement, locomotor time 20.20.61.5-0.9-0.90.71.2-0.60.6-0.30.40.60.8-0.8
Total resting periods, locomotor time 20.10.31.0-0.6-0.60.31.0-0.30.20.00.00.40.9-0.9
Rest time, locomotor task time 21.22.04.21.81.7-1.7-1.21.6-2.01.2-1.3-0.9-0.50.5
Distance moved, locomotor task time 20.70.91.8-1.1-1.01.30.6-1.31.2-1.01.20.50.0-0.0
Vertical activity count, locomotor time 20.40.92.6-0.1-0.10.7-0.8-0.80.3-1.21.3-0.2-1.61.6
Light reinforcement 10.00.10.30.40.2-0.1-0.60.4-0.10.20.1-0.1-0.40.4
Light reinforcement 20.61.33.21.61.5-1.5-1.00.8-1.00.9-0.2-1.8-0.40.4
Bone: marrow area0.92.36.21.31.2-1.6-0.92.2-1.42.2-2.50.10.8-0.8
Bone: maximum diameter0.10.21.20.30.2-0.4-0.3-0.40.10.20.6-1.1-0.30.3
Bone: maximum force1.83.66.9-2.2-2.21.82.6-1.62.0-0.80.71.42.3-2.3
Bone: maximum moment1.83.46.3-2.2-2.11.82.5-1.52.0-0.80.61.52.1-2.1
Mean time between licks in bursts0.10.71.5-0.7-0.91.10.5-0.61.2-0.90.61.1-0.20.2
Mean num. licks in bursts0.10.20.90.10.2-0.2-0.30.7-0.40.3-0.90.6-0.10.1
Cd content in liver1.41.53.11.51.3-1.4-1.41.2-1.81.5-0.7-1.3-0.20.2
Co content in liver1.01.13.81.11.1-0.6-0.80.4-0.7-0.70.1-0.6-2.02.0
Cu content in liver0.10.10.3-0.2-0.20.10.40.30.50.4-0.20.20.6-0.6
Fe content in liver0.20.30.5-0.4-0.50.50.6-0.70.5-0.60.7-0.0-0.20.2
K content in liver0.80.81.7-1.0-0.90.81.3-0.31.1-0.3-0.41.10.9-0.9
Mg content in liver0.30.41.00.40.3-0.40.70.90.10.6-1.00.40.7-0.7
Mn content in liver2.12.45.0-1.8-1.71.42.2-2.01.6-1.11.40.31.2-1.2
Na content in liver0.50.62.1-0.1-0.10.4-0.1-1.00.6-0.81.4-0.9-0.80.8
Rb content in liver1.01.23.11.21.0-1.2-0.01.8-0.91.3-1.70.20.6-0.6
Se content in liver0.30.30.70.60.5-0.8-0.30.4-0.50.8-0.3-0.80.4-0.4
Sr content in liver1.71.43.3-1.3-1.21.40.5-1.81.4-1.41.70.1-0.40.4
Zn content in liver0.30.30.8-0.8-0.70.70.2-0.40.9-0.40.00.70.0-0.0
Bone: minimum diameter1.22.46.30.90.9-1.3-0.12.0-1.12.2-2.50.41.7-1.7
Time in familiar zone, hab. session 10.30.40.70.50.5-0.60.30.7-0.70.8-0.6-0.30.7-0.7
Time in novel zone, hab. session 10.30.31.10.30.20.0-0.80.10.3-0.40.30.0-1.01.0
Total zone transitions, hab. session 10.60.81.3-1.2-1.01.11.0-0.80.8-0.80.41.10.6-0.6
Total locomotion distance, hab. session 10.30.41.20.50.8-0.7-0.50.8-1.10.6-1.0-0.20.0-0.0
Locomotion velocity, hab. session 10.10.10.4-0.10.2-0.1-0.00.3-0.60.2-0.70.20.2-0.2
Time in familiar zone, hab. session 20.20.20.5-0.3-0.20.50.6-0.30.5-0.70.50.4-0.30.3
Time in novel zone, hab. session 20.20.20.4-0.1-0.2-0.1-0.20.3-0.10.6-0.70.30.7-0.7
Total zone transitions, hab. session 22.83.69.1-1.7-1.91.22.40.10.70.6-0.82.63.0-3.0
Total locomotion distance, hab. session 20.91.23.1-0.3-0.30.11.11.0-0.31.0-1.31.31.8-1.8
Locomotion velocity, hab. session 20.91.12.9-0.00.0-0.20.81.2-0.61.2-1.41.01.7-1.7
Novel to familiar place preference ratio0.20.30.8-0.6-0.50.00.2-0.70.30.40.4-0.50.9-0.9
Novelty place preference0.20.20.7-0.2-0.2-0.3-0.1-0.3-0.00.70.1-0.60.8-0.8
Time in novel zone, NPP test0.20.20.6-0.2-0.2-0.3-0.2-0.2-0.10.7-0.0-0.50.8-0.8
Total zone transitions, NPP test1.82.64.6-2.0-2.01.82.2-1.01.4-0.80.22.01.6-1.6
Total locomotion distance, NPP test0.30.41.3-0.5-0.40.40.70.3-0.1-0.1-0.81.20.6-0.6
Locomotion velocity, NPP test0.20.31.0-0.5-0.40.40.60.1-0.0-0.1-0.71.00.6-0.6
Intraocular pressure1.32.14.81.61.7-1.8-1.60.5-2.20.70.2-2.2-1.11.1
Delta distance traveled before/after self-admin0.10.10.40.20.2-0.1-0.2-0.1-0.5-0.30.1-0.2-0.70.7
Delta ambulatory time before/after self-admin0.00.10.2-0.0-0.00.10.1-0.2-0.1-0.40.3-0.1-0.40.4
Parametrial fat weight3.07.011.62.93.0-3.3-2.83.1-3.42.8-2.8-1.7-0.60.6
Pavlov. Cond. lever latency0.20.30.70.70.6-0.5-0.80.4-0.60.3-0.1-0.6-0.50.5
Pavlov. Cond. magazine entry latency0.30.41.5-0.4-0.30.10.70.20.00.5-0.40.41.2-1.2
Pavlov. Cond. change in total contacts0.20.20.60.10.3-0.50.0-0.0-0.40.60.1-0.80.6-0.6
Pavlov. Cond. index score0.00.10.1-0.3-0.10.10.3-0.30.1-0.10.4-0.10.3-0.3
Pavlov. Cond. latency score0.00.10.2-0.3-0.10.00.4-0.10.20.00.10.10.4-0.4
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.30.20.5-0.10.4-0.1-0.10.40.4-0.4
Pavlov. Cond. magazine entry number0.10.10.60.20.1-0.1-0.30.6-0.10.3-0.70.4-0.20.2
Pavlov. Cond. intertrial magazine entries0.40.51.00.70.6-0.6-1.00.1-1.00.2-0.1-1.0-0.80.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.4-0.30.20.3-0.40.3-0.10.40.10.4-0.4
Pavlov. Cond. response bias0.10.10.4-0.2-0.10.20.1-0.50.1-0.30.6-0.30.0-0.0
Pavlov. Cond. lever latency0.30.41.00.50.7-0.4-0.80.9-0.60.6-1.00.1-0.20.2
Pavlov. Cond. magazine entry latency3.24.69.1-2.5-2.52.13.0-1.82.2-1.11.31.82.2-2.2
Pavlov. Cond. change in total contacts0.61.33.4-1.1-1.20.61.8-1.10.7-0.01.0-0.01.7-1.7
Pavlov. Cond. index score1.42.24.9-1.7-1.71.32.2-1.51.4-0.81.20.81.6-1.6
Pavlov. Cond. latency score1.11.84.1-1.5-1.51.22.0-1.51.3-0.81.20.71.4-1.4
Pavlov. Cond. lever contacts0.30.41.0-0.6-0.70.50.9-0.90.6-0.51.0-0.00.5-0.5
Pavlov. Cond. magazine entry number4.86.312.22.93.0-2.6-3.52.5-2.61.4-1.9-1.7-2.42.4
Pavlov. Cond. intertrial magazine entries0.61.32.01.41.4-1.3-1.41.1-1.40.9-0.7-1.1-0.70.7
Pavlov. Cond. lever-magazine prob. diff.1.82.75.9-1.9-1.91.52.4-1.71.6-0.91.31.01.7-1.7
Pavlov. Cond. response bias1.31.94.2-1.5-1.61.22.0-1.41.3-0.71.30.71.4-1.4
Time in closed arm before self-admin0.40.61.20.90.7-1.1-0.30.9-0.51.1-0.6-0.60.8-0.8
Time in closed arm after self-admin0.10.10.40.20.3-0.10.10.40.20.1-0.60.30.0-0.0
Time in open arm before self-admin0.40.51.8-0.3-0.30.8-0.70.20.4-0.9-0.51.3-0.90.9
Time in open arm after self-admin0.10.10.2-0.3-0.40.20.1-0.3-0.1-0.40.40.20.0-0.0
Bone: periosteal estimation0.00.10.30.20.3-0.4-0.30.4-0.10.6-0.6-0.20.2-0.2
Bone: periosteal perimeter0.20.31.00.00.0-0.30.60.10.30.7-0.3-0.41.0-1.0
Bone: post-yield work2.13.612.5-0.8-0.6-0.31.31.1-0.22.5-2.00.93.5-3.5
Progressive ratio test 1 active lever presses0.10.20.50.40.2-0.6-0.10.5-0.50.7-0.4-0.3-0.10.1
Progressive ratio test 1 breakpoint0.10.10.40.30.2-0.5-0.00.4-0.40.7-0.3-0.3-0.10.1
Progressive ratio test 1 inactive lever presses0.00.10.20.30.3-0.2-0.00.2-0.40.4-0.1-0.40.4-0.4
Progressive ratio test 2 active lever presses1.52.13.61.81.6-1.9-1.11.6-1.71.8-1.2-1.30.4-0.4
Progressive ratio test 2 breakpoint1.62.03.51.81.6-1.9-1.11.5-1.71.7-1.1-1.40.3-0.3
Progressive ratio test 2 inactive lever presses2.57.812.63.63.2-3.4-2.73.2-3.53.1-2.5-2.2-0.10.1
Incentive Sensitization - Responses0.20.41.80.10.0-0.20.50.40.10.7-0.4-0.01.3-1.3
Incentive Sensitization - Breakpoint0.20.51.60.30.3-0.40.30.5-0.10.8-0.5-0.31.3-1.3
Sum of active levers in priming session hrs 5-62.11.97.0-0.10.00.50.1-2.10.1-1.32.7-2.1-1.31.3
Progressive ratio0.72.24.9-1.4-1.41.11.80.20.60.7-1.12.02.2-2.2
Food seeking constrained by brief footshock0.20.30.7-0.6-0.50.90.3-0.40.6-0.60.20.70.5-0.5
Seeking ratio, punishment vs. effort0.61.33.01.21.2-0.7-1.70.3-0.5-0.60.3-1.0-1.71.7
Retroperitoneal fat weight6.729.946.26.86.6-6.6-6.36.4-6.35.0-5.0-3.9-2.42.4
Reaction time number correct0.10.51.3-0.2-0.20.60.2-0.90.9-1.01.1-0.3-0.70.7
Reaction time mean minus median0.42.44.1-2.0-1.91.61.7-2.01.2-1.11.80.71.1-1.1
Reaction time mean minus median AUC0.21.63.3-1.5-1.41.51.1-1.81.1-1.41.80.50.2-0.2
Reaction time num false alarms0.20.41.50.10.30.2-0.40.0-0.0-0.8-0.10.3-1.21.2
Reaction time num false alarms AUC0.20.61.8-0.6-0.40.90.4-0.60.6-1.30.30.9-0.80.8
Reaction time trials correct on left0.10.51.3-0.2-0.20.60.2-0.90.9-1.01.1-0.3-0.70.7
Reaction time trials on left0.20.61.6-0.3-0.30.70.3-1.11.0-1.11.3-0.3-0.70.7
Reaction time mean0.00.10.7-0.0-0.2-0.0-0.1-0.1-0.80.10.5-0.00.2-0.2
Reaction time mean AUC0.00.10.80.1-0.0-0.2-0.2-0.0-0.90.30.4-0.20.3-0.3
Median of all reaction times0.20.31.80.50.4-0.6-0.40.5-1.30.6-0.1-0.20.2-0.2
Reaction time omissions1.11.83.3-1.8-1.71.41.4-1.81.2-1.31.60.80.6-0.6
Reaction time false alarm rate0.10.20.6-0.20.00.20.00.1-0.1-0.6-0.50.8-0.60.6
Reaction time premature initiation rate2.23.56.3-2.2-2.42.52.0-1.82.0-2.01.51.90.4-0.4
Reaction time premature initiations1.75.08.7-2.4-2.63.02.1-2.62.7-2.72.41.6-0.10.1
Std. dev. reaction times0.20.71.4-1.0-1.10.80.7-1.10.2-0.61.20.40.6-0.6
Reaction time trials completed0.20.61.6-0.3-0.30.70.3-1.11.0-1.11.3-0.3-0.70.7
Reaction time trials AUC0.10.51.2-0.2-0.20.60.2-0.90.9-1.01.1-0.3-0.70.7
Run reversals in cocaine runway, females1.31.54.2-1.2-1.01.41.3-0.01.4-0.5-0.72.11.2-1.2
Run reversals in cocaine runway, males0.70.81.80.60.7-0.3-0.7-0.5-0.2-1.11.0-1.0-1.41.4
Latency to leave start box in cocaine runway0.50.71.90.10.1-0.80.50.7-0.61.1-0.90.11.4-1.4
Latency to leave start box in cocaine runway, F0.30.30.9-0.0-0.0-0.50.10.5-0.30.7-0.70.30.9-0.9
Latency to leave start box in cocaine runway, M0.30.30.9-0.2-0.1-0.20.9-0.1-0.20.20.0-0.11.0-1.0
Std. dev. time between licks in bursts0.30.61.4-0.3-0.40.7-0.3-0.30.5-1.10.40.9-1.21.2
Total sessions with >9 infusions0.30.40.8-0.4-0.40.20.70.50.20.7-0.90.80.8-0.8
Short access day 1 total inactive lever presses1.02.02.91.71.5-1.7-1.71.7-1.51.5-1.4-1.0-0.40.4
Short access day 10 total inactive lever presses0.00.20.40.50.6-0.5-0.20.5-0.50.1-0.6-0.10.4-0.4
Short access day 1 total infusions0.81.53.81.11.1-1.5-0.91.8-0.81.7-1.9-0.30.4-0.4
Short access day 10 total infusions1.01.74.50.1-0.0-0.60.61.5-0.31.9-2.10.81.8-1.8
Short access total infusions0.50.72.70.10.1-0.40.11.2-0.11.3-1.60.70.9-0.9
Short access day 1 locomotion0.71.12.21.11.0-1.3-0.11.5-0.91.4-1.5-0.30.8-0.8
Short access day 10 total locomotion0.31.32.51.01.1-1.0-0.21.5-1.11.4-1.6-0.41.2-1.2
Short access total locomotion0.91.42.61.11.1-1.3-0.31.6-1.21.6-1.6-0.40.9-0.9
One hour access (0.3 mA shock)4.25.08.42.92.7-2.8-2.22.7-2.82.2-2.2-1.5-0.30.3
Compulsive drug intake2.02.95.6-1.8-1.82.21.4-1.81.9-2.41.61.8-0.60.6
One hour access (shock baseline)2.97.612.73.43.3-3.6-2.73.0-3.33.0-2.4-2.5-0.20.2
Social response proportion0.50.61.5-0.7-0.80.61.2-0.60.70.00.40.31.2-1.2
Social responses0.20.30.5-0.5-0.60.60.7-0.60.7-0.50.60.40.3-0.3
Social time0.30.40.8-0.6-0.70.80.1-0.80.7-0.80.90.6-0.20.2
Soleus weight3.08.813.73.63.7-3.2-3.73.1-3.41.9-2.5-2.0-2.32.3
Bone: stiffness1.42.55.0-1.8-1.81.22.2-1.11.6-0.10.51.12.2-2.2
Tibialis anterior weight7.325.343.9-5.9-5.76.05.0-6.65.7-6.05.52.80.1-0.1
Time to tail flick, vehicle, before self-admin0.40.51.7-0.6-0.50.51.3-0.00.6-0.0-0.40.71.0-1.0
Time to tail flick, vehicle, after self-admin0.71.34.0-1.3-1.21.01.00.10.90.1-1.12.01.3-1.3
Time to tail flick, test, before self-admin1.41.66.10.90.8-0.8-0.31.9-0.91.4-2.50.71.1-1.1
Time to tail flick, test, after self-admin0.10.10.40.20.2-0.20.3-0.2-0.40.10.3-0.6-0.10.1
Delta time to tail flick, vehicle, before/after SA0.60.61.3-0.9-0.90.70.6-0.10.5-0.0-0.41.21.1-1.1
Delta time to tail flick, test, before/after SA1.92.38.0-0.6-0.60.80.2-2.20.5-1.82.8-1.2-1.91.9
Tibia length0.61.65.4-1.0-1.01.10.1-2.10.5-1.32.3-0.5-1.21.2
Ambulatory time before self-admin0.20.52.2-0.3-0.4-0.20.8-0.20.00.60.0-0.21.5-1.5
Ambulatory time after self-admin0.61.01.70.70.6-1.20.10.8-1.31.3-0.8-0.81.2-1.2
Bone: tissue strength0.10.10.30.10.0-0.1-0.00.2-0.10.4-0.3-0.20.5-0.5
Total heroin consumption2.63.15.9-2.4-2.32.01.6-2.32.1-1.31.90.80.5-0.5
Bone: trabecular number0.81.64.1-1.2-1.40.61.6-0.10.70.8-0.51.22.0-2.0
Bone: trabecular spacing0.20.30.90.50.5-0.2-0.90.4-0.5-0.3-0.10.1-0.70.7
Bone: trabecular thickness0.40.62.10.50.4-0.70.31.1-0.31.4-1.10.00.7-0.7
Bone: trabecular tissue density3.15.59.22.93.0-2.6-2.71.8-2.81.1-1.0-2.3-2.22.2
Water consumed over 24 hours0.61.12.3-1.1-1.41.31.1-1.01.5-0.81.01.10.6-0.6
Number of responses in last shaping day0.00.00.2-0.1-0.2-0.20.1-0.10.4-0.30.30.10.0-0.0