Trappc5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Trappc5 0.08 0.04 7.1e-06 0.03 0.04 0.04 0.04 1.8e-04 2.7e-05 9.4e-06 2.5e-05
2 PL mRNA stability Trappc5 0.11 0.05 1.9e-06 0.05 0.05 0.05 0.06 2.2e-06 2.5e-06 6.2e-06 4.1e-07
3 Brain mRNA stability Trappc5 0.07 0.04 3.8e-05 0.06 0.05 0.04 0.05 2.2e-06 2.2e-05 7.5e-05 1.8e-05
4 Adipose mRNA stability Trappc5 0.05 0.03 4.7e-03 0.03 0.01 0.01 0.02 3.2e-04 3.9e-02 3.1e-02 2.2e-03
5 NAcc mRNA stability Trappc5 0.13 0.06 1.4e-10 0.08 0.08 0.08 0.08 2.2e-09 5.4e-10 6.2e-10 6.0e-10
6 BLA intron excision ratio chr12_1739134_1740114 0.06 0.04 6.6e-04 0.08 0.07 0.06 0.07 3.8e-05 1.7e-04 3.6e-04 9.5e-05
7 PL alternative TSS NM_001108850.2 0.1 0.05 1.8e-12 0.12 0.12 0.11 0.11 5.4e-13 6.2e-13 2.7e-12 1.5e-12
8 PL alternative TSS XM_039089624.1 0.1 0.05 6.4e-12 0.11 0.11 0.1 0.11 2.2e-12 3.0e-12 1.9e-11 6.6e-12
9 Adipose alternative TSS NM_001108850.2 0.05 0.03 3.0e-06 0.03 0.04 0.04 0.04 8.0e-04 2.5e-05 7.8e-05 9.0e-06
10 Adipose alternative TSS XM_039089624.1 0.05 0.03 2.9e-06 0.02 0.04 0.04 0.04 9.1e-04 3.2e-05 8.2e-05 1.6e-05
11 BLA alternative TSS NM_001108850.2 0.12 0.06 9.7e-07 0.12 0.13 0.11 0.14 4.1e-07 2.0e-07 1.4e-06 8.7e-08
12 BLA alternative TSS XM_039089624.1 0.11 0.06 3.4e-06 0.12 0.12 0.1 0.12 1.0e-06 5.3e-07 5.6e-06 3.2e-07
13 NAcc alternative TSS NM_001108850.2 0.05 0.03 1.3e-06 0.06 0.05 0.04 0.05 4.6e-07 8.4e-07 6.5e-06 2.7e-06
14 NAcc alternative TSS XM_039089624.1 0.05 0.03 1.2e-06 0.05 0.05 0.04 0.04 8.1e-07 1.4e-06 3.0e-05 6.9e-06
15 PL gene expression Trappc5 0.07 0.04 1.7e-05 0.03 0.04 0.04 0.03 1.5e-04 1.9e-05 3.7e-05 2.1e-04
16 Adipose isoform ratio NM_001108850.2 0.04 0.02 3.0e-04 0.03 0.02 0.01 0.02 2.0e-04 3.1e-03 7.6e-03 1.0e-03
17 Adipose isoform ratio XM_039089624.1 0.04 0.02 3.8e-04 0.03 0.02 0.01 0.02 2.4e-04 3.8e-03 8.2e-03 1.2e-03
18 Liver alternative TSS NM_001108850.2 0.05 0.03 1.4e-04 0.04 0.03 0.03 0.03 1.5e-05 3.4e-04 7.6e-04 1.1e-04
19 Liver alternative TSS XM_039089624.1 0.04 0.03 2.0e-04 0.04 0.03 0.02 0.03 2.0e-05 4.9e-04 9.8e-04 1.5e-04
20 Brain gene expression Trappc5 0.17 0.08 1.1e-15 0.16 0.17 0.17 0.18 6.2e-15 1.5e-15 1.8e-15 1.5e-16
21 BLA gene expression Trappc5 0.14 0.07 1.0e-03 0.04 0.06 0.05 0.04 2.7e-03 4.7e-04 7.1e-04 2.0e-03
22 pVTA gene expression Trappc5 0.11 0.07 2.1e-03 0.08 0.06 0.1 0.04 3.1e-04 1.2e-03 6.7e-05 5.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density2.54.219.44.4-1.31.70.9-0.52.12.1-2.0-1.31.3-2.02.02.0-2.0-2.82.0-2.02.0-2.0-1.2-2.42.2
Area under the delay curve3.73.95.8-1.4-0.90.60.5-1.3-2.4-2.42.42.2-2.12.2-2.2-2.22.22.4-2.12.1-2.12.12.32.1-1.4
BMI with tail0.92.811.43.3-3.43.21.8-2.6-0.8-0.80.81.0-1.00.8-0.8-0.80.80.6-0.90.9-0.90.92.61.20.7
BMI without tail1.32.611.42.6-3.43.22.5-2.8-0.8-0.80.80.7-0.70.8-0.8-0.80.81.0-0.90.9-0.90.91.61.5-0.7
Body weight3.213.585.89.3-8.08.15.8-6.00.10.1-0.1-0.30.3-0.00.00.0-0.0-0.50.0-0.00.0-0.02.91.40.5
Weight adjusted by age1.21.42.41.0-0.10.1-0.10.21.31.3-1.3-1.21.3-1.31.31.3-1.3-1.31.5-1.51.5-1.5-0.8-0.91.4
Bone surface1.52.719.64.4-2.42.61.5-1.41.21.2-1.2-0.70.7-1.21.21.2-1.2-1.81.2-1.21.2-1.20.1-1.21.7
Bone volume1.72.916.64.1-1.31.50.5-0.51.61.6-1.6-0.80.8-1.61.61.6-1.6-2.41.6-1.61.6-1.6-0.4-2.02.2
Breakpoint value in progressive ratio session2.22.43.91.1-1.21.11.3-1.6-1.7-1.71.72.0-1.91.7-1.7-1.71.71.2-1.71.7-1.71.71.40.9-0.9
Number of licking bursts1.11.35.0-0.40.0-0.20.10.41.21.2-1.2-2.22.2-1.21.21.2-1.2-0.31.3-1.31.3-1.3-1.30.4-0.9
Context. condit. distance diff. score1.92.39.23.0-2.42.52.6-2.4-1.0-1.01.01.5-1.51.0-1.0-1.01.00.2-1.11.1-1.11.11.00.1-0.6
Locomotion velocity, session 10.60.71.0-1.00.10.10.2-0.2-1.0-1.01.00.9-0.91.0-1.0-1.01.00.9-0.90.9-0.90.90.60.6-0.6
Locomotion distance, session 10.30.42.2-1.51.1-1.0-0.60.6-0.5-0.50.50.5-0.50.5-0.5-0.50.50.6-0.50.5-0.50.5-0.10.2-0.4
Locomotion velocity, session 20.50.62.5-1.60.00.10.2-0.2-0.8-0.80.80.3-0.30.8-0.8-0.80.81.1-0.90.9-0.90.90.31.1-1.0
Locomotion distance, session 20.40.63.8-1.91.4-1.4-0.60.8-0.4-0.40.40.2-0.30.3-0.3-0.30.30.5-0.60.6-0.60.6-0.9-0.0-0.9
Locomotion velocity, session 30.30.30.80.9-0.70.70.6-0.7-0.5-0.50.50.8-0.80.5-0.5-0.50.50.2-0.40.4-0.40.40.50.0-0.2
Locomotion distance, session 30.50.51.20.40.8-0.9-0.40.60.70.7-0.7-0.40.4-0.70.70.7-0.7-0.90.8-0.80.8-0.8-1.0-1.10.3
Stereotopy head waving bouts, day 30.91.15.62.4-1.21.00.7-0.60.90.9-0.9-0.80.8-1.01.01.0-1.0-1.11.0-1.01.0-1.0-0.5-0.70.9
Stereotopy head waving duration, day 30.10.10.70.4-0.10.2-0.30.20.40.4-0.4-0.40.4-0.40.40.4-0.4-0.30.4-0.40.4-0.4-0.0-0.20.8
Locomotion velocity, session 72.72.94.8-1.0-0.70.91.0-1.2-1.9-1.91.91.5-1.52.0-2.0-2.02.02.2-1.81.8-1.81.81.82.1-1.8
Locomotion distance, session 71.41.73.7-0.6-0.50.41.2-0.9-1.5-1.51.51.3-1.31.5-1.5-1.51.51.5-1.41.4-1.41.40.81.1-1.9
Stereotopy head waving bouts, day 70.10.20.6-0.60.8-0.7-0.50.4-0.3-0.30.30.5-0.50.3-0.3-0.30.30.2-0.30.3-0.30.3-0.2-0.20.1
Stereotopy head waving duration, day 70.10.20.9-1.00.7-0.6-0.60.5-0.3-0.30.30.2-0.20.2-0.2-0.20.20.3-0.20.2-0.20.2-0.00.10.1
Locomotion velocity, session 80.70.91.6-0.2-0.91.00.7-1.0-0.9-0.91.00.6-0.61.0-1.0-1.01.01.1-1.01.0-1.01.01.01.2-0.8
Locomotion distance, session 80.81.12.61.4-1.51.61.6-1.6-0.9-0.90.90.9-1.00.8-0.8-0.80.80.6-1.01.0-1.01.00.80.6-0.7
Degree of sensitization distance1.71.73.2-1.7-0.10.10.4-0.4-1.4-1.41.40.9-0.91.4-1.4-1.41.41.8-1.41.4-1.41.40.91.6-1.6
Degree of sensitization stereotypy0.20.20.4-0.60.4-0.4-0.40.1-0.6-0.60.60.6-0.60.5-0.5-0.50.50.5-0.60.6-0.60.60.30.2-0.0
Conditioned locomotion0.81.02.21.00.5-0.7-0.80.71.01.0-1.0-0.30.3-1.01.01.0-1.0-1.41.0-1.01.0-1.0-0.6-1.51.5
Cocaine response after cond. corrected0.40.42.7-0.3-0.30.3-1.10.20.50.5-0.6-0.70.6-0.60.60.6-0.6-0.20.5-0.50.5-0.50.90.31.6
Cocaine response after cond. not corrected0.20.32.10.2-0.60.5-0.6-0.3-0.2-0.20.10.3-0.40.1-0.1-0.10.10.1-0.10.1-0.10.11.30.31.4
Cocaine response before conditioning1.31.64.41.5-0.60.51.2-1.2-1.4-1.41.42.1-2.01.4-1.4-1.41.40.4-1.21.2-1.21.20.5-0.2-0.7
Saline control response0.60.72.41.3-0.80.81.6-0.60.70.7-0.7-0.80.9-0.70.70.7-0.7-0.80.8-0.80.8-0.8-1.3-0.5-0.8
Bone: connectivity density2.03.120.14.5-2.22.61.9-1.41.41.4-1.4-1.01.0-1.41.41.4-1.4-2.01.3-1.31.3-1.3-0.7-1.41.3
Bone: cortical apparent density0.81.01.8-0.9-0.20.2-0.0-0.4-1.2-1.21.10.9-0.91.1-1.1-1.11.11.3-1.11.1-1.11.11.11.2-0.8
Bone: cortical area1.42.15.92.4-2.42.32.1-2.2-1.1-1.11.11.1-1.11.1-1.1-1.11.10.7-1.01.0-1.01.01.60.9-0.9
Bone: cortical porosity0.10.10.30.50.0-0.1-0.00.10.40.4-0.3-0.30.3-0.30.30.3-0.3-0.40.4-0.40.4-0.4-0.3-0.30.1
Bone: cortical porosity0.00.10.20.10.3-0.40.10.1-0.2-0.20.20.3-0.30.2-0.2-0.20.2-0.0-0.10.1-0.10.1-0.3-0.3-0.4
Bone: cortical thickness1.01.65.42.0-2.32.11.9-2.0-0.8-0.80.90.8-0.80.9-0.9-0.90.90.7-0.80.8-0.80.81.50.9-0.8
Bone: cortical thickness0.50.62.40.9-1.31.21.5-1.2-0.5-0.50.50.2-0.20.5-0.5-0.50.50.4-0.40.4-0.40.40.20.5-1.4
Bone: cortical tissue density0.60.71.4-1.0-0.00.0-0.2-0.2-1.0-1.01.00.8-0.80.9-0.9-0.90.91.2-0.90.9-0.90.91.01.1-0.7
Condit. Reinf. active minus inactive responses0.40.40.9-0.70.2-0.1-0.4-0.0-0.8-0.80.80.9-0.90.7-0.7-0.70.70.7-0.60.6-0.60.60.80.40.1
Condit. Reinf. active-inactive response ratio0.60.71.6-0.0-0.40.40.1-0.5-1.0-1.00.91.1-1.10.9-0.9-0.90.90.9-0.90.9-0.90.91.30.7-0.0
Condit. Reinf. active responses0.30.41.1-0.50.3-0.2-0.1-0.1-0.8-0.80.81.1-1.00.7-0.7-0.70.70.5-0.70.7-0.70.70.30.1-0.2
Condit. Reinf. inactive responses0.30.40.9-0.90.8-0.7-0.10.3-0.6-0.60.60.8-0.80.6-0.6-0.60.60.3-0.60.6-0.60.6-0.5-0.3-0.7
Incentive salience index mean0.30.31.2-0.50.5-0.4-0.30.1-0.7-0.70.71.1-1.00.6-0.6-0.60.60.3-0.50.5-0.50.50.3-0.20.1
Condit. Reinf. lever presses0.20.31.2-0.10.5-0.5-0.10.0-0.5-0.50.51.1-1.10.5-0.5-0.50.5-0.1-0.50.5-0.50.5-0.2-0.70.0
Condit. Reinf. active minus inactive responses2.73.36.00.1-1.92.22.5-2.2-1.9-1.91.91.2-1.21.9-1.9-1.91.91.9-1.81.8-1.81.81.31.9-2.1
Condit. Reinf. active-inactive response ratio3.13.35.7-0.7-1.41.61.9-1.8-1.9-1.91.91.1-1.22.0-2.0-2.02.02.1-1.91.9-1.91.91.22.2-2.4
Condit. Reinf. active responses2.73.77.00.9-2.12.42.6-2.4-2.0-2.01.91.7-1.72.0-2.0-2.02.01.6-1.81.8-1.81.81.31.5-1.9
Condit. Reinf. inactive responses0.20.31.81.3-0.60.80.9-0.7-0.2-0.20.20.7-0.70.2-0.2-0.20.2-0.3-0.20.2-0.20.20.1-0.50.1
Condit. Reinf. lever presses0.50.71.31.1-0.61.01.1-1.0-0.8-0.80.81.1-1.10.8-0.8-0.80.80.2-0.80.8-0.80.80.4-0.1-0.2
Condit. Reinf. lever reinforcers received2.73.76.30.5-1.82.12.5-2.3-2.1-2.12.11.8-1.82.1-2.1-2.12.11.7-1.91.9-1.91.91.31.5-2.1
Conditioned reinforcement - actives0.90.95.11.4-1.71.92.3-1.6-0.2-0.20.2-0.40.40.2-0.2-0.20.20.3-0.20.2-0.20.2-0.10.7-1.3
Conditioned reinforcement - inactives0.70.81.50.50.4-0.4-0.10.51.01.0-1.0-1.21.2-1.01.01.0-1.0-0.81.0-1.01.0-1.0-1.2-0.60.1
Conditioned locomotion0.50.64.21.8-1.31.42.0-1.4-0.2-0.20.20.2-0.20.2-0.2-0.20.2-0.2-0.20.2-0.20.2-0.4-0.2-0.8
Patch foraging indifference point 0 sec2.43.96.30.81.2-1.2-1.21.72.32.3-2.3-1.51.6-2.22.22.2-2.2-2.52.2-2.22.2-2.2-2.0-2.51.7
Patch foraging indifference point AUC0.30.30.80.9-0.60.70.6-0.40.40.4-0.5-0.50.6-0.60.60.6-0.6-0.50.6-0.60.6-0.6-0.6-0.30.3
Delay disc. indifference point, 0s delay3.43.79.2-0.2-2.01.70.7-1.9-2.1-2.12.01.4-1.41.9-1.9-1.91.92.6-1.91.9-1.91.93.02.9-1.1
Delay disc. indifference point, 16s delay1.21.22.0-1.4-0.40.20.3-0.6-1.3-1.31.31.2-1.11.2-1.2-1.21.21.4-1.11.1-1.11.11.21.2-1.0
Delay disc. indifference point, 2s delay4.24.78.3-1.0-0.70.30.0-1.2-2.7-2.72.62.9-2.82.4-2.4-2.42.42.4-2.32.3-2.32.32.81.8-0.8
Delay disc. indifference point, 24s delay0.90.83.5-1.90.1-0.3-0.2-0.2-1.1-1.11.00.7-0.70.9-0.9-0.90.91.3-0.80.8-0.80.80.81.2-0.8
Delay disc. indifference point, 4s delay2.02.13.8-0.7-0.50.2-0.1-0.9-1.9-1.91.82.0-1.91.5-1.5-1.51.51.7-1.61.6-1.61.61.91.3-0.4
Delay disc. indifference point, 8s delay1.41.42.2-1.1-0.30.10.3-0.6-1.5-1.51.41.4-1.41.3-1.3-1.31.31.3-1.31.3-1.31.31.01.0-1.1
Indifference point function ln k0.20.21.10.00.7-0.70.00.40.40.4-0.4-0.30.3-0.40.40.4-0.4-0.50.2-0.20.2-0.2-1.0-0.6-0.6
Indifference point function log k0.20.21.10.00.7-0.70.00.40.40.4-0.4-0.30.3-0.40.40.4-0.4-0.50.2-0.20.2-0.2-1.0-0.6-0.6
Patch foraging total patch changes 0 sec3.15.18.20.71.6-1.5-1.31.92.52.5-2.6-1.71.8-2.52.52.5-2.5-2.82.5-2.52.5-2.5-2.4-2.91.9
Patch foraging total patch changes 12 sec1.51.93.21.30.2-0.3-0.80.71.51.5-1.6-0.91.0-1.51.51.5-1.5-1.71.6-1.61.6-1.6-0.9-1.61.8
Patch foraging total patch changes 18 sec3.34.35.90.61.2-0.9-1.01.62.42.4-2.4-1.92.0-2.32.32.3-2.3-2.42.4-2.42.4-2.4-2.2-2.21.8
Patch foraging total patch changes 24 sec1.92.36.40.81.4-1.4-0.51.21.51.5-1.5-0.70.7-1.51.51.5-1.5-2.11.6-1.61.6-1.6-2.5-2.50.8
Patch foraging total patch changes 6 sec2.33.35.71.10.8-0.7-0.71.22.02.0-2.1-1.41.5-2.12.12.1-2.1-2.42.1-2.12.1-2.1-1.8-2.31.8
Patch foraging time to switch 0 sec0.91.47.5-1.4-0.2-0.1-1.50.0-1.0-1.01.10.8-0.81.1-1.1-1.11.11.6-1.01.0-1.01.02.71.80.7
Patch foraging water rate 0 sec2.33.710.42.60.1-0.11.30.32.02.0-2.0-1.61.6-1.91.91.9-1.9-2.72.1-2.12.1-2.1-3.2-2.70.1
Patch foraging water rate 12 sec0.30.42.90.80.5-0.50.80.10.30.3-0.3-0.10.2-0.40.40.3-0.3-0.90.6-0.60.6-0.6-1.7-1.3-0.7
Patch foraging water rate 18 sec0.60.83.00.00.2-0.51.0-0.4-1.0-1.01.01.1-1.11.0-1.0-1.01.00.5-0.80.8-0.80.8-0.6-0.2-1.7
Patch foraging water rate 24 sec0.50.73.92.0-0.70.41.6-0.60.50.5-0.4-0.30.3-0.40.40.4-0.4-0.90.3-0.30.3-0.3-1.4-1.0-1.0
Patch foraging water rate 6 sec0.40.63.41.60.3-0.30.70.10.50.5-0.50.1-0.2-0.40.40.4-0.4-1.40.4-0.40.4-0.4-1.6-1.8-0.0
Seeking ratio, delayed vs. immediate footshock1.92.25.3-2.02.3-2.2-2.12.21.31.3-1.3-1.51.5-1.31.31.3-1.3-0.81.2-1.21.2-1.2-1.3-0.70.9
Distance traveled before self-admin1.51.62.4-0.9-0.10.10.4-0.4-1.5-1.51.51.3-1.41.5-1.5-1.51.51.3-1.61.6-1.61.60.70.9-1.3
Distance traveled after self-admin0.30.30.80.2-0.20.40.7-0.4-0.7-0.70.70.6-0.60.7-0.7-0.70.70.6-0.60.6-0.60.60.10.4-0.9
Extensor digitorum longus weight1.24.934.95.9-4.44.34.2-3.7-0.3-0.30.40.7-0.70.4-0.4-0.40.4-0.6-0.30.3-0.30.31.0-0.1-0.4
Bone: elastic displacement0.20.20.80.9-0.40.50.3-0.20.50.5-0.5-0.50.5-0.50.50.5-0.5-0.50.4-0.40.4-0.4-0.3-0.30.2
Bone: elastic work0.91.28.32.9-1.71.71.5-1.10.80.8-0.7-0.70.7-0.70.70.7-0.7-1.10.8-0.80.8-0.8-0.3-0.60.2
Bone: endosteal estimation0.71.42.51.6-0.20.30.50.11.41.4-1.3-1.31.3-1.31.31.3-1.3-1.51.3-1.31.3-1.3-1.4-1.30.3
Bone: endosteal perimeter0.20.54.62.2-0.80.81.3-0.80.20.2-0.10.2-0.2-0.10.10.1-0.1-0.80.2-0.20.2-0.2-0.6-0.9-0.3
Epididymis fat weight0.20.62.51.6-0.70.80.5-0.7-0.6-0.60.61.3-1.30.6-0.6-0.60.6-0.1-0.60.6-0.60.60.8-0.40.8
Delta time in closed arm before/after self-admin0.60.61.1-0.1-0.30.30.8-0.6-0.8-0.80.80.9-0.90.9-0.9-0.90.90.8-0.80.8-0.80.8-0.00.6-1.1
Delta time in open arm before/after self-admin0.50.52.4-1.31.4-1.3-1.61.10.10.1-0.10.3-0.3-0.10.10.1-0.1-0.20.1-0.10.1-0.10.3-0.40.9
Diff in mean of infusions in LGA sessions0.10.20.60.8-0.10.20.5-0.3-0.4-0.40.40.7-0.70.4-0.4-0.40.4-0.1-0.30.3-0.30.30.0-0.40.1
Delay discount exponential model param3.73.96.01.40.8-0.5-0.41.22.52.5-2.4-2.42.3-2.22.22.2-2.2-2.42.2-2.22.2-2.2-2.2-1.91.5
Extinction: sum of active levers before priming0.60.61.4-0.50.4-0.3-0.3-0.0-0.9-0.90.91.2-1.10.9-0.9-0.90.90.7-0.80.8-0.80.80.70.3-0.2
Active lever presses in extinction session 60.10.10.70.8-0.30.30.3-0.3-0.0-0.00.00.1-0.20.0-0.0-0.00.0-0.2-0.10.1-0.10.10.2-0.20.3
Bone: final force0.81.25.61.9-2.42.22.1-1.9-0.3-0.30.4-0.00.10.4-0.4-0.40.40.5-0.30.3-0.30.30.91.1-1.2
Bone: final moment0.60.94.41.7-2.12.01.8-1.6-0.2-0.20.2-0.20.30.2-0.2-0.20.20.4-0.10.1-0.10.10.70.9-1.0
Food consumed during 24 hour testing period0.60.71.80.10.5-0.4-0.10.51.01.0-0.9-1.41.3-0.80.80.8-0.8-0.81.0-1.01.0-1.0-1.2-0.60.1
Glucose0.50.81.8-1.3-0.10.4-0.2-0.3-0.9-0.90.90.6-0.60.9-0.9-0.90.91.3-0.90.9-0.90.91.21.4-0.5
Heart weight0.91.37.5-1.50.5-0.11.6-0.3-0.9-0.90.90.4-0.51.2-1.2-1.21.20.7-1.21.2-1.21.2-1.20.3-2.7
Delay discount hyperbolic model param3.53.75.71.40.7-0.4-0.31.12.42.4-2.3-2.32.2-2.12.12.1-2.1-2.32.1-2.12.1-2.1-2.2-1.91.3
Intermittent access intake day 1-15 change1.41.42.51.0-0.20.10.20.31.41.4-1.4-1.61.6-1.31.31.3-1.3-1.21.4-1.41.4-1.4-1.2-0.80.6
Intermittent access intake escalation0.80.71.51.2-0.30.30.5-0.10.90.9-0.9-1.01.0-0.90.90.9-0.9-0.91.0-1.01.0-1.0-1.0-0.70.3
Intermittent access intake escalation 20.50.51.00.40.4-0.6-0.20.50.80.8-0.8-0.70.8-0.80.80.8-0.8-0.80.8-0.80.8-0.8-1.0-0.80.4
Intermitt. access day 1 inactive lever presses1.41.53.40.20.8-0.9-0.30.91.31.3-1.3-1.41.4-1.31.31.3-1.3-1.21.4-1.41.4-1.4-1.8-1.1-0.1
Intermitt. access day 15 inactive lever presses1.41.54.10.20.6-0.6-1.61.11.41.4-1.4-1.31.3-1.41.41.4-1.4-1.01.3-1.31.3-1.3-0.1-0.62.0
Intermitt. access escalation Index0.20.20.6-0.30.5-0.20.40.1-0.5-0.50.50.7-0.70.5-0.5-0.50.50.0-0.50.5-0.50.5-0.5-0.4-0.6
Intermittent access day 1 total infusions1.01.21.8-1.20.8-0.50.1-0.1-1.3-1.31.31.3-1.31.2-1.2-1.21.21.0-1.31.3-1.31.30.20.5-0.9
Intermittent access day 15 total infusions0.10.10.60.00.6-0.40.20.10.00.0-0.00.0-0.0-0.00.00.0-0.0-0.30.0-0.00.0-0.0-0.8-0.5-0.1
Intermittent access terminal intake (last 3 days)0.10.10.5-0.50.7-0.6-0.40.3-0.0-0.00.00.0-0.10.0-0.0-0.00.0-0.0-0.00.0-0.00.0-0.3-0.20.2
Intermittent access total infusions0.50.61.0-0.80.5-0.3-0.1-0.1-0.9-0.90.91.0-1.00.9-0.9-0.90.90.7-0.90.9-0.90.90.40.3-0.3
Intermittent access day 1 locomotion1.61.74.0-1.51.1-0.9-0.30.1-1.5-1.51.52.0-2.01.5-1.5-1.51.50.8-1.51.5-1.51.50.4-0.1-0.3
Intermittent access day 15 total locomotion0.80.91.9-0.20.5-0.40.9-0.4-1.0-1.01.01.4-1.41.0-1.0-1.01.00.3-1.01.0-1.01.0-0.7-0.4-1.2
Intermittent access total locomotion1.71.94.0-1.20.9-0.80.3-0.2-1.6-1.61.62.0-2.01.6-1.6-1.61.60.9-1.61.6-1.61.6-0.00.0-1.1
Intermittent access standard deviation2.32.43.40.80.5-0.5-1.11.01.81.8-1.8-1.81.8-1.81.81.8-1.8-1.51.8-1.81.8-1.8-0.8-1.01.7
Left kidney weight1.85.028.35.3-4.74.64.5-3.50.60.6-0.5-0.90.9-0.50.50.5-0.5-0.80.6-0.60.6-0.60.20.3-0.9
Right kidney weight1.54.323.14.8-4.44.43.7-3.10.70.7-0.7-1.01.1-0.60.60.6-0.6-0.80.7-0.70.7-0.70.50.4-0.1
Cocaine induced anxiety0.50.62.00.80.2-0.30.1-0.2-0.8-0.80.81.4-1.40.8-0.8-0.80.80.2-0.90.9-0.90.90.4-0.40.2
Post-drug Anxiety2.42.74.4-1.50.5-0.5-0.5-0.1-1.8-1.81.82.1-2.11.9-1.9-1.91.91.7-2.02.0-2.02.01.61.1-0.5
Baseline Anxiety1.41.57.1-2.70.5-0.4-1.20.4-1.1-1.11.10.7-0.81.1-1.1-1.11.11.7-1.21.2-1.21.21.61.6-0.4
Tail length1.85.525.84.8-5.15.04.6-4.2-0.7-0.70.70.3-0.20.6-0.6-0.60.60.5-0.60.6-0.60.61.31.5-1.4
Length with tail3.312.172.28.5-7.67.56.4-5.8-0.0-0.00.1-0.60.60.0-0.0-0.00.0-0.40.1-0.10.1-0.11.81.3-1.0
Length without tail2.35.036.26.0-4.74.83.5-3.40.10.1-0.1-0.10.1-0.00.00.0-0.0-0.70.2-0.20.2-0.21.90.40.5
Times rat made contact with spout0.50.61.80.7-1.11.11.4-1.1-0.5-0.50.5-0.0-0.00.6-0.6-0.60.60.7-0.50.5-0.50.50.40.9-1.2
Lifetime Intake0.30.40.9-1.00.5-0.2-0.40.0-0.7-0.70.70.7-0.70.7-0.7-0.70.70.7-0.70.7-0.70.70.70.50.2
Liver weight, left2.33.85.41.70.3-0.2-0.50.92.32.3-2.2-2.12.1-2.22.22.2-2.2-2.32.2-2.22.2-2.2-1.7-1.91.7
Liver weight, right0.91.510.73.3-1.71.81.6-1.20.90.9-0.9-0.50.6-0.90.90.9-0.9-1.40.9-0.90.9-0.9-0.5-1.00.8
Locomotor activity1.01.66.51.5-2.01.92.5-2.0-1.0-1.00.91.0-0.90.9-0.9-0.90.90.7-0.90.9-0.90.90.10.6-1.9
Locomotor testing distance0.40.61.31.2-0.40.50.7-0.20.80.8-0.8-0.50.6-0.90.90.9-0.9-1.00.7-0.70.7-0.7-1.0-0.90.2
Locomotor testing rearing0.91.42.70.41.0-0.8-0.81.11.31.3-1.4-0.60.7-1.41.41.4-1.4-1.51.1-1.11.1-1.1-1.2-1.61.4
Locomotion in novel chamber0.10.21.50.30.4-0.20.9-0.00.10.1-0.1-0.30.3-0.10.10.1-0.1-0.20.1-0.10.1-0.1-1.2-0.4-1.0
Locomotion in novel chamber post-restriction0.80.95.21.6-1.31.32.3-1.4-0.5-0.50.50.4-0.40.6-0.6-0.60.60.0-0.40.4-0.40.4-0.5-0.0-2.0
Fecal boli incidents, locomotor time 10.60.63.61.9-1.21.21.7-1.1-0.3-0.30.30.4-0.40.4-0.4-0.40.40.0-0.40.4-0.40.4-0.1-0.0-1.2
Change in fecal boli incidents, locomotor task0.40.41.8-0.90.7-0.5-1.40.80.50.5-0.5-0.70.7-0.50.50.5-0.5-0.10.6-0.60.6-0.60.10.21.0
Time >=10cm from walls, locomotor time 11.21.22.6-0.60.1-0.2-0.5-0.2-1.3-1.31.31.6-1.61.3-1.3-1.31.31.1-1.11.1-1.11.11.60.70.3
Bouts of movement, locomotor time 10.20.31.61.3-0.90.91.2-0.8-0.0-0.00.0-0.10.10.0-0.0-0.00.0-0.10.2-0.20.2-0.2-0.30.0-0.3
Total resting periods, locomotor time 10.20.31.41.1-1.00.91.2-0.9-0.2-0.20.20.1-0.10.2-0.2-0.20.20.00.0-0.00.0-0.0-0.10.1-0.4
Rest time, locomotor task time 10.20.21.21.1-0.90.80.8-0.7-0.0-0.00.10.2-0.20.1-0.1-0.10.1-0.10.1-0.10.1-0.10.30.1-0.0
Distance moved, locomotor task time 10.30.31.6-1.30.3-0.20.10.0-0.6-0.60.50.3-0.40.6-0.6-0.60.60.6-0.60.6-0.60.60.10.4-0.8
Vertical activity count, locomotor time 10.20.20.8-0.3-0.30.20.7-0.4-0.4-0.40.40.1-0.10.4-0.4-0.40.40.4-0.30.3-0.30.3-0.20.3-0.9
Time >=10cm from walls, locomotor time 21.21.23.41.0-1.61.70.7-1.4-1.0-1.01.01.3-1.30.9-0.9-0.90.90.8-1.01.0-1.01.01.90.90.2
Bouts of movement, locomotor time 20.30.32.41.5-0.90.61.1-0.80.00.00.00.2-0.2-0.00.00.0-0.0-0.50.2-0.20.2-0.2-0.3-0.50.2
Total resting periods, locomotor time 20.30.32.41.5-0.80.50.9-0.60.20.2-0.2-0.00.0-0.20.20.2-0.2-0.70.4-0.40.4-0.4-0.3-0.60.5
Rest time, locomotor task time 20.10.10.50.30.4-0.2-0.30.2-0.1-0.10.20.5-0.50.2-0.2-0.20.2-0.2-0.10.1-0.10.10.1-0.40.7
Distance moved, locomotor task time 20.30.31.0-1.00.00.00.10.20.40.4-0.5-0.91.0-0.50.50.5-0.50.10.6-0.60.6-0.6-0.40.4-0.7
Vertical activity count, locomotor time 20.70.81.70.6-0.80.81.1-0.50.70.7-0.8-1.31.3-0.90.90.9-0.9-0.30.9-0.90.9-0.9-1.00.1-0.9
Light reinforcement 11.52.83.9-1.4-0.40.40.4-0.8-1.9-1.91.91.8-1.81.9-1.9-1.91.91.9-2.02.0-2.02.01.61.6-1.2
Light reinforcement 20.20.31.2-1.10.7-0.8-0.80.70.40.4-0.4-0.60.6-0.50.50.5-0.5-0.10.3-0.30.3-0.3-0.5-0.00.0
Bone: marrow area0.71.62.51.5-0.20.20.50.21.41.4-1.4-1.41.3-1.41.41.4-1.4-1.61.4-1.41.4-1.4-1.5-1.30.3
Bone: maximum diameter0.40.75.92.4-1.51.41.3-1.10.30.3-0.2-0.10.1-0.20.20.2-0.2-0.60.4-0.40.4-0.40.2-0.30.0
Bone: maximum force0.50.85.42.3-1.91.81.8-1.50.10.1-0.1-0.20.2-0.10.10.1-0.1-0.30.3-0.30.3-0.30.20.1-0.6
Bone: maximum moment0.40.74.32.1-1.61.51.5-1.20.30.3-0.3-0.40.4-0.30.30.3-0.3-0.40.5-0.50.5-0.50.0-0.1-0.4
Mean time between licks in bursts0.40.62.7-1.31.6-1.6-1.41.40.30.3-0.3-0.10.1-0.30.30.3-0.3-0.40.3-0.30.3-0.3-0.7-0.80.4
Mean num. licks in bursts0.50.61.90.8-0.40.60.4-0.6-0.8-0.80.81.4-1.40.8-0.8-0.80.80.2-0.90.9-0.90.90.8-0.10.4
Cd content in liver1.11.25.1-1.72.3-2.2-1.11.60.50.5-0.6-0.60.5-0.80.80.8-0.8-0.60.4-0.40.4-0.4-2.1-1.1-0.3
Co content in liver2.02.33.70.10.8-0.7-0.51.11.81.8-1.8-1.91.8-1.81.81.8-1.8-1.61.6-1.61.6-1.6-1.9-1.40.7
Cu content in liver0.50.72.20.40.9-0.8-0.50.80.80.8-0.8-0.30.3-0.80.80.8-0.8-1.20.7-0.70.7-0.7-1.2-1.50.8
Fe content in liver0.91.15.62.4-1.31.21.8-1.5-0.6-0.60.61.3-1.30.6-0.6-0.60.6-0.5-0.70.7-0.70.70.0-0.8-0.2
K content in liver0.10.10.20.4-0.30.40.2-0.3-0.1-0.10.10.4-0.40.2-0.2-0.20.2-0.1-0.30.3-0.30.30.3-0.20.3
Mg content in liver0.10.10.50.6-0.70.70.6-0.50.10.1-0.1-0.10.10.0-0.0-0.00.0-0.00.0-0.00.0-0.00.20.2-0.1
Mn content in liver0.40.41.5-1.21.0-0.7-1.01.00.60.6-0.6-1.00.9-0.50.50.5-0.5-0.20.3-0.30.3-0.3-0.6-0.00.4
Na content in liver0.50.60.90.5-0.90.90.7-0.9-0.7-0.70.70.7-0.70.8-0.8-0.80.80.6-0.80.8-0.80.80.90.6-0.4
Rb content in liver0.40.63.0-1.71.4-1.2-1.11.1-0.1-0.10.10.7-0.70.2-0.2-0.20.2-0.3-0.30.3-0.30.3-0.3-0.90.9
Se content in liver2.42.95.21.8-1.82.11.5-2.0-1.7-1.71.72.2-2.31.7-1.7-1.71.70.8-1.81.8-1.81.82.00.50.2
Sr content in liver2.72.54.40.10.6-0.7-0.91.11.81.8-1.8-2.12.1-1.81.81.8-1.8-1.41.9-1.91.9-1.9-1.3-0.90.9
Zn content in liver2.22.45.42.3-0.80.80.5-0.11.81.8-1.8-1.71.7-1.81.81.8-1.8-1.81.7-1.71.7-1.7-1.1-1.21.0
Bone: minimum diameter0.00.00.10.00.1-0.10.10.10.20.2-0.1-0.20.2-0.10.10.1-0.1-0.10.2-0.20.2-0.2-0.3-0.1-0.4
Time in familiar zone, hab. session 11.81.72.5-0.01.0-1.4-1.61.41.41.4-1.4-1.21.3-1.41.41.4-1.4-1.21.5-1.51.5-1.5-0.8-1.01.5
Time in novel zone, hab. session 10.90.91.80.4-1.01.31.2-1.2-0.9-0.90.90.7-0.80.9-0.9-0.90.90.8-1.01.0-1.01.00.80.9-1.0
Total zone transitions, hab. session 10.91.22.6-1.60.8-0.7-0.20.1-1.3-1.31.31.3-1.31.2-1.2-1.21.21.2-1.31.3-1.31.30.30.6-0.9
Total locomotion distance, hab. session 10.60.92.0-0.50.2-0.1-0.1-0.2-1.1-1.11.11.4-1.41.1-1.1-1.11.10.8-1.21.2-1.21.20.70.3-0.0
Locomotion velocity, hab. session 11.01.42.7-1.10.5-0.5-0.3-0.1-1.4-1.41.41.6-1.71.3-1.3-1.31.31.1-1.41.4-1.41.40.80.5-0.3
Time in familiar zone, hab. session 20.10.10.70.0-0.2-0.1-0.40.10.20.2-0.2-0.10.1-0.20.20.2-0.2-0.20.3-0.30.3-0.30.50.00.8
Time in novel zone, hab. session 20.30.30.9-0.50.4-0.20.2-0.0-0.6-0.60.60.5-0.50.5-0.5-0.50.50.5-0.60.6-0.60.6-0.20.2-1.0
Total zone transitions, hab. session 20.20.21.0-0.8-0.40.30.5-0.4-0.4-0.40.4-0.10.10.3-0.3-0.30.30.7-0.40.4-0.40.40.00.9-1.0
Total locomotion distance, hab. session 20.20.21.0-1.00.2-0.30.0-0.0-0.5-0.50.50.3-0.30.4-0.4-0.40.40.6-0.50.5-0.50.50.00.4-0.5
Locomotion velocity, hab. session 20.20.21.4-1.20.2-0.30.0-0.0-0.5-0.50.40.2-0.20.4-0.4-0.40.40.6-0.40.4-0.40.4-0.10.5-0.6
Novel to familiar place preference ratio0.20.20.8-0.8-0.00.30.3-0.2-0.4-0.40.4-0.10.10.4-0.4-0.40.40.8-0.40.4-0.40.40.10.9-0.9
Novelty place preference0.30.31.3-1.10.20.10.10.0-0.4-0.40.4-0.0-0.00.4-0.4-0.40.40.8-0.50.5-0.50.50.10.8-0.9
Time in novel zone, NPP test0.20.20.8-0.90.00.20.2-0.1-0.4-0.40.40.0-0.00.4-0.4-0.40.40.8-0.40.4-0.40.40.10.8-0.8
Total zone transitions, NPP test0.30.40.5-0.3-0.40.30.6-0.6-0.7-0.70.70.6-0.60.7-0.7-0.70.70.6-0.70.7-0.70.70.30.5-0.7
Total locomotion distance, NPP test1.21.63.3-0.0-0.60.50.7-1.0-1.5-1.51.51.8-1.81.4-1.4-1.41.41.1-1.51.5-1.51.51.10.6-0.5
Locomotion velocity, NPP test1.11.63.0-0.0-0.60.40.9-1.1-1.5-1.51.51.7-1.71.4-1.4-1.41.41.0-1.51.5-1.51.50.70.5-0.8
Intraocular pressure0.40.65.12.3-1.00.61.2-0.70.40.4-0.40.00.0-0.40.40.4-0.4-1.10.6-0.60.6-0.6-0.5-1.10.1
Delta distance traveled before/after self-admin0.50.50.90.50.1-0.10.10.20.80.8-0.8-0.80.9-0.90.90.9-0.9-0.60.9-0.90.9-0.9-0.7-0.40.2
Delta ambulatory time before/after self-admin0.40.40.80.10.6-0.5-0.40.50.70.7-0.7-0.50.6-0.80.80.8-0.8-0.50.9-0.90.9-0.9-0.6-0.50.5
Parametrial fat weight0.30.51.50.1-0.30.3-0.30.30.90.9-0.8-1.21.2-0.70.70.7-0.7-0.30.8-0.80.8-0.80.10.30.4
Pavlov. Cond. lever latency0.81.03.11.7-1.21.61.1-0.61.01.0-1.0-1.21.2-0.90.90.9-0.9-0.80.9-0.90.9-0.9-0.4-0.20.3
Pavlov. Cond. magazine entry latency0.30.40.70.1-0.70.30.7-0.8-0.7-0.70.60.6-0.50.7-0.7-0.70.70.6-0.60.6-0.60.60.50.5-0.7
Pavlov. Cond. change in total contacts1.61.72.8-0.6-0.50.20.2-0.8-1.5-1.51.51.5-1.51.5-1.5-1.51.51.5-1.51.5-1.51.51.71.3-0.4
Pavlov. Cond. index score0.50.61.2-0.1-0.2-0.10.1-0.5-0.9-0.90.91.1-1.10.9-0.9-0.90.90.7-0.90.9-0.90.90.80.4-0.4
Pavlov. Cond. latency score0.70.91.7-0.5-0.1-0.30.0-0.5-1.2-1.21.11.3-1.31.1-1.1-1.11.10.9-1.11.1-1.11.10.90.6-0.5
Pavlov. Cond. lever contacts0.60.71.4-1.20.8-1.1-0.80.3-0.9-0.90.91.2-1.10.9-0.9-0.90.90.7-0.80.8-0.80.80.60.2-0.1
Pavlov. Cond. magazine entry number0.60.71.3-0.70.9-0.6-1.21.10.90.9-0.8-1.01.0-0.90.90.9-0.9-0.50.8-0.80.8-0.8-0.5-0.30.8
Pavlov. Cond. intertrial magazine entries0.40.52.0-1.21.4-1.3-1.11.20.40.4-0.4-0.30.3-0.40.40.4-0.4-0.30.5-0.50.5-0.5-0.8-0.60.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.0-0.2-0.2-0.0-0.4-0.7-0.70.70.9-0.90.7-0.7-0.70.70.5-0.70.7-0.70.70.70.3-0.1
Pavlov. Cond. response bias0.40.51.00.3-0.50.20.5-0.7-0.8-0.80.81.0-1.00.8-0.8-0.80.80.5-0.80.8-0.80.80.60.2-0.3
Pavlov. Cond. lever latency2.43.24.60.20.7-1.1-1.51.42.02.0-2.1-2.02.1-2.12.12.1-2.1-1.62.1-2.12.1-2.1-1.2-1.11.5
Pavlov. Cond. magazine entry latency2.93.44.7-1.3-0.30.40.5-0.9-2.2-2.22.22.2-2.22.1-2.1-2.12.12.0-2.12.1-2.12.11.81.5-1.3
Pavlov. Cond. change in total contacts1.21.72.4-0.6-0.30.51.2-0.9-1.5-1.51.51.4-1.41.5-1.5-1.51.51.2-1.51.5-1.51.50.50.8-1.6
Pavlov. Cond. index score2.53.24.7-0.8-0.30.51.0-1.0-2.1-2.12.12.1-2.22.1-2.1-2.12.11.7-2.12.1-2.12.11.11.1-1.6
Pavlov. Cond. latency score2.42.94.4-0.8-0.30.40.9-1.0-2.0-2.02.02.1-2.12.0-2.0-2.02.01.7-2.02.0-2.02.01.21.1-1.4
Pavlov. Cond. lever contacts1.92.64.60.2-0.60.91.1-1.2-1.9-1.91.92.1-2.11.9-1.9-1.91.91.3-2.02.0-2.02.01.20.7-1.0
Pavlov. Cond. magazine entry number2.22.73.81.5-0.20.0-0.50.61.91.9-2.0-1.81.9-1.91.91.9-1.9-1.81.9-1.91.9-1.9-1.1-1.21.6
Pavlov. Cond. intertrial magazine entries0.20.20.50.7-0.40.40.6-0.30.40.4-0.4-0.50.5-0.40.40.4-0.4-0.40.4-0.40.4-0.4-0.6-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.2.73.44.9-1.0-0.20.41.0-1.0-2.2-2.22.22.1-2.22.2-2.2-2.22.21.9-2.22.2-2.22.21.21.2-1.8
Pavlov. Cond. response bias2.93.96.9-0.3-0.40.71.2-1.2-2.3-2.32.32.6-2.62.3-2.3-2.32.31.7-2.42.4-2.42.41.30.9-1.5
Time in closed arm before self-admin0.80.92.20.8-0.70.70.8-0.11.01.0-1.0-1.51.4-1.01.01.0-1.0-1.00.9-0.90.9-0.9-1.0-0.6-0.1
Time in closed arm after self-admin0.30.31.80.1-0.30.41.3-0.4-0.0-0.00.0-0.10.10.1-0.1-0.10.1-0.2-0.10.1-0.10.1-1.3-0.4-1.3
Time in open arm before self-admin0.40.51.00.2-0.50.30.7-0.7-0.8-0.80.80.6-0.50.7-0.7-0.70.70.9-0.60.6-0.60.60.30.8-1.0
Time in open arm after self-admin0.10.10.70.4-0.0-0.2-0.60.10.00.0-0.00.2-0.1-0.10.10.1-0.10.00.2-0.20.2-0.20.80.10.9
Bone: periosteal estimation0.40.75.62.4-1.61.61.6-1.30.20.2-0.2-0.20.2-0.10.10.1-0.1-0.50.3-0.30.3-0.3-0.0-0.2-0.5
Bone: periosteal perimeter0.81.33.81.9-1.41.41.8-1.5-0.9-0.91.01.4-1.41.0-1.0-1.01.00.2-0.90.9-0.90.90.6-0.1-1.0
Bone: post-yield work0.20.31.51.2-0.20.30.2-0.10.40.4-0.40.2-0.2-0.40.40.4-0.4-1.00.4-0.40.4-0.4-0.3-1.10.8
Progressive ratio test 1 active lever presses0.10.10.40.1-0.20.50.6-0.4-0.1-0.10.1-0.20.20.1-0.1-0.10.10.3-0.20.2-0.20.2-0.10.4-0.6
Progressive ratio test 1 breakpoint0.10.10.50.0-0.40.70.6-0.6-0.2-0.20.2-0.20.20.2-0.2-0.20.20.4-0.20.2-0.20.20.10.7-0.7
Progressive ratio test 1 inactive lever presses0.30.41.70.50.10.10.7-0.10.50.5-0.5-0.80.7-0.50.50.5-0.5-0.50.5-0.50.5-0.5-1.3-0.4-1.0
Progressive ratio test 2 active lever presses0.60.62.40.3-0.60.81.5-1.0-0.7-0.70.70.3-0.40.7-0.7-0.70.70.6-0.80.8-0.80.8-0.30.5-1.5
Progressive ratio test 2 breakpoint0.80.93.6-0.4-0.40.61.4-0.9-1.0-1.01.00.5-0.61.0-1.0-1.01.00.9-1.11.1-1.11.1-0.30.8-1.9
Progressive ratio test 2 inactive lever presses1.21.45.11.80.1-0.01.00.01.11.1-1.1-1.11.1-1.11.11.1-1.1-1.51.1-1.11.1-1.1-2.2-1.5-0.5
Incentive Sensitization - Responses0.30.31.1-0.20.2-0.10.7-0.2-0.6-0.60.60.6-0.60.6-0.6-0.60.60.3-0.70.7-0.70.7-0.5-0.0-1.0
Incentive Sensitization - Breakpoint0.30.41.1-0.30.3-0.10.7-0.2-0.6-0.60.60.6-0.60.6-0.6-0.60.60.3-0.70.7-0.70.7-0.5-0.1-1.1
Sum of active levers in priming session hrs 5-60.40.42.1-0.1-0.30.2-0.6-0.2-0.6-0.60.50.8-0.80.6-0.6-0.60.60.5-0.50.5-0.50.51.50.40.9
Progressive ratio0.50.61.6-1.21.1-1.2-1.31.10.60.6-0.6-0.60.6-0.70.70.7-0.7-0.20.6-0.60.6-0.6-0.6-0.30.7
Food seeking constrained by brief footshock3.44.15.4-0.31.9-2.3-2.32.32.12.1-2.1-1.51.6-2.12.12.1-2.1-2.02.1-2.12.1-2.1-1.9-2.12.3
Seeking ratio, punishment vs. effort0.30.31.71.3-0.40.30.3-0.10.70.7-0.7-0.40.4-0.50.50.5-0.5-0.90.6-0.60.6-0.6-0.4-0.70.4
Retroperitoneal fat weight0.92.99.4-0.2-0.50.6-0.6-0.6-1.8-1.81.82.3-2.41.9-1.9-1.91.91.4-1.91.9-1.91.93.11.11.0
Reaction time number correct0.81.13.10.50.50.00.50.41.11.1-1.1-1.21.2-1.11.11.1-1.1-1.31.3-1.31.3-1.3-1.8-1.20.2
Reaction time mean minus median5.87.711.30.5-2.22.02.2-2.7-3.2-3.23.23.4-3.33.2-3.2-3.23.22.5-2.92.9-2.92.92.51.9-1.8
Reaction time mean minus median AUC2.12.85.2-0.7-0.50.31.0-1.1-2.1-2.12.12.3-2.22.0-2.0-2.02.01.5-1.81.8-1.81.81.00.8-1.3
Reaction time num false alarms1.92.64.0-0.5-0.40.31.1-1.1-1.8-1.81.82.0-2.01.9-1.9-1.91.91.5-1.91.9-1.91.90.70.9-1.8
Reaction time num false alarms AUC1.11.63.50.1-0.40.20.9-1.0-1.5-1.51.41.9-1.81.5-1.5-1.51.50.9-1.41.4-1.41.40.50.3-1.1
Reaction time trials correct on left0.81.13.10.50.50.00.50.41.11.1-1.1-1.21.2-1.11.11.1-1.1-1.31.3-1.31.3-1.3-1.8-1.20.2
Reaction time trials on left0.71.02.80.50.40.00.60.41.01.0-1.0-1.11.1-1.01.01.0-1.0-1.21.2-1.21.2-1.2-1.7-1.20.1
Reaction time mean3.04.26.7-2.4-0.0-0.3-0.4-0.6-2.4-2.42.42.1-2.12.3-2.3-2.32.32.6-2.32.3-2.32.32.22.1-1.3
Reaction time mean AUC2.93.95.7-2.30.1-0.4-0.5-0.5-2.3-2.32.32.2-2.22.2-2.2-2.22.22.4-2.12.1-2.12.12.01.9-1.2
Median of all reaction times2.23.09.1-3.00.8-1.0-1.30.3-1.8-1.81.81.5-1.51.8-1.8-1.81.82.3-1.81.8-1.81.81.81.9-0.9
Reaction time omissions1.31.73.3-1.4-0.1-0.10.3-0.6-1.8-1.81.71.8-1.71.5-1.5-1.51.51.5-1.21.2-1.21.21.21.0-0.7
Reaction time false alarm rate2.02.75.4-0.0-0.70.30.8-1.2-1.9-1.91.92.3-2.32.0-2.0-2.02.01.5-1.91.9-1.91.91.30.9-1.2
Reaction time premature initiation rate0.81.01.80.1-0.70.50.7-0.9-1.3-1.31.31.0-1.01.2-1.2-1.21.21.2-1.11.1-1.11.10.81.0-1.0
Reaction time premature initiations0.20.30.70.3-0.40.40.8-0.6-0.7-0.70.70.5-0.40.6-0.6-0.60.60.5-0.40.4-0.40.40.00.3-0.7
Std. dev. reaction times3.54.97.4-0.9-1.10.81.0-1.6-2.7-2.72.72.7-2.72.6-2.6-2.62.62.3-2.42.4-2.42.42.21.8-1.3
Reaction time trials completed0.71.02.80.50.40.00.60.41.01.0-1.0-1.11.1-1.01.01.0-1.0-1.21.2-1.21.2-1.2-1.7-1.20.1
Reaction time trials AUC0.71.03.10.40.6-0.10.40.51.01.0-1.0-1.01.0-1.01.01.0-1.0-1.31.2-1.21.2-1.2-1.8-1.30.2
Run reversals in cocaine runway, females0.20.20.6-0.70.8-0.5-0.70.70.20.2-0.2-0.20.1-0.10.10.1-0.1-0.40.2-0.20.2-0.2-0.4-0.50.6
Run reversals in cocaine runway, males0.60.62.7-0.61.0-1.1-0.20.70.60.6-0.7-0.70.7-0.70.70.7-0.7-0.70.6-0.60.6-0.6-1.6-0.8-0.3
Latency to leave start box in cocaine runway0.50.51.7-0.9-0.60.50.2-0.4-0.5-0.50.50.3-0.30.7-0.7-0.70.71.1-0.80.8-0.80.81.01.3-0.7
Latency to leave start box in cocaine runway, F0.20.20.9-0.2-0.70.80.0-0.20.30.3-0.2-0.70.7-0.10.10.1-0.10.40.0-0.00.0-0.00.61.0-0.1
Latency to leave start box in cocaine runway, M0.80.81.6-0.90.5-0.40.3-0.1-0.8-0.80.91.2-1.30.9-0.9-0.90.90.7-1.21.2-1.21.2-0.10.0-1.0
Std. dev. time between licks in bursts0.10.10.40.6-0.30.20.6-0.4-0.3-0.30.30.6-0.60.3-0.3-0.30.3-0.1-0.20.2-0.20.2-0.2-0.4-0.6
Total sessions with >9 infusions0.20.20.3-0.1-0.20.40.3-0.5-0.6-0.60.60.5-0.50.5-0.5-0.50.50.5-0.50.5-0.50.50.50.5-0.3
Short access day 1 total inactive lever presses0.30.40.6-0.10.5-0.6-0.40.50.70.7-0.7-0.80.8-0.70.70.7-0.7-0.50.7-0.70.7-0.7-0.7-0.30.1
Short access day 10 total inactive lever presses2.42.74.72.2-0.30.1-0.20.41.91.9-1.9-1.81.8-1.91.91.9-1.9-1.81.9-1.91.9-1.9-1.2-1.41.4
Short access day 1 total infusions0.90.93.4-1.31.3-1.0-1.91.30.80.8-0.8-0.70.7-0.80.80.8-0.8-0.50.8-0.80.8-0.80.2-0.41.7
Short access day 10 total infusions0.20.21.0-0.71.0-0.7-0.80.5-0.2-0.20.20.4-0.40.2-0.2-0.20.20.1-0.20.2-0.20.20.2-0.20.5
Short access total infusions0.30.31.4-1.20.4-0.1-1.00.3-0.2-0.20.20.0-0.00.2-0.2-0.20.20.6-0.20.2-0.20.21.20.80.8
Short access day 1 locomotion1.92.13.4-1.80.4-0.40.1-0.4-1.7-1.71.71.5-1.51.7-1.7-1.71.71.7-1.61.6-1.61.60.91.3-1.4
Short access day 10 total locomotion0.40.41.6-0.51.2-1.1-1.00.90.40.4-0.40.1-0.1-0.40.40.4-0.4-0.70.4-0.40.4-0.4-0.6-1.10.9
Short access total locomotion0.60.71.8-1.30.6-0.5-0.60.1-0.9-0.90.91.0-1.00.9-0.9-0.90.90.8-0.90.9-0.90.90.90.40.1
One hour access (0.3 mA shock)0.40.53.6-0.71.2-0.90.30.60.40.4-0.4-0.50.5-0.40.40.4-0.4-0.50.3-0.30.3-0.3-1.9-0.8-1.0
Compulsive drug intake0.90.96.0-2.52.0-1.8-1.41.60.20.2-0.2-0.30.3-0.20.20.2-0.20.00.1-0.10.1-0.1-0.8-0.3-0.3
One hour access (shock baseline)0.40.52.81.2-0.70.91.7-1.1-0.5-0.50.50.5-0.50.5-0.5-0.50.50.0-0.50.5-0.50.5-0.5-0.1-1.0
Social response proportion4.24.510.41.2-3.23.03.2-3.0-1.9-1.91.81.1-1.11.8-1.8-1.81.82.1-1.71.7-1.71.71.82.6-2.7
Social responses0.81.05.01.7-1.61.42.2-1.6-0.7-0.70.60.8-0.70.7-0.7-0.70.70.3-0.50.5-0.50.50.00.2-1.5
Social time1.21.66.1-2.50.9-1.3-0.40.3-1.4-1.41.41.2-1.11.4-1.4-1.41.41.6-0.90.9-0.90.90.71.2-1.5
Soleus weight0.41.110.13.2-1.41.21.6-1.10.60.6-0.6-0.00.0-0.50.50.5-0.5-1.40.5-0.50.5-0.5-0.5-1.30.1
Bone: stiffness0.71.03.01.2-1.31.11.7-1.4-0.9-0.91.00.9-0.81.0-1.0-1.01.00.7-0.70.7-0.70.70.50.6-1.5
Tibialis anterior weight1.96.437.46.1-5.25.04.5-4.4-0.8-0.80.91.0-1.00.8-0.8-0.80.8-0.0-0.60.6-0.60.61.90.7-0.5
Time to tail flick, vehicle, before self-admin2.42.54.7-1.6-0.60.70.1-0.8-1.7-1.71.71.2-1.31.7-1.7-1.71.72.2-1.81.8-1.81.81.92.1-1.1
Time to tail flick, vehicle, after self-admin0.80.91.4-1.1-0.20.40.4-0.4-1.1-1.11.10.9-1.01.0-1.0-1.01.01.1-1.21.2-1.21.20.60.8-0.9
Time to tail flick, test, before self-admin0.30.31.61.3-0.70.90.8-0.50.40.4-0.4-0.50.5-0.30.30.3-0.3-0.20.4-0.40.4-0.4-0.10.2-0.1
Time to tail flick, test, after self-admin0.30.31.30.1-0.80.80.1-0.5-0.4-0.40.30.4-0.40.4-0.4-0.40.40.5-0.40.4-0.40.41.20.70.4
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.30.9-0.7-0.40.70.40.4-0.5-0.10.1-0.50.50.5-0.5-0.80.4-0.40.4-0.4-0.9-1.00.4
Delta time to tail flick, test, before/after SA0.10.10.9-0.40.3-0.5-0.80.40.00.0-0.00.3-0.30.0-0.0-0.00.0-0.20.1-0.10.1-0.10.4-0.41.0
Tibia length0.82.311.42.3-3.43.11.9-2.10.70.7-0.7-1.61.6-0.80.80.8-0.80.10.9-0.90.9-0.91.21.50.0
Ambulatory time before self-admin2.42.54.1-0.5-0.50.40.9-0.9-1.9-1.91.92.0-2.01.9-1.9-1.91.91.3-1.91.9-1.91.91.00.7-1.3
Ambulatory time after self-admin0.50.51.10.3-0.20.40.5-0.5-0.9-0.90.91.0-1.00.8-0.8-0.80.80.6-0.80.8-0.80.80.40.2-0.5
Bone: tissue strength2.52.43.20.11.0-1.0-1.21.41.81.8-1.8-1.71.7-1.71.71.7-1.7-1.61.8-1.81.8-1.8-1.3-1.31.5
Total heroin consumption2.12.45.3-1.11.0-1.0-0.4-0.0-1.8-1.81.82.3-2.31.8-1.8-1.81.81.3-1.81.8-1.81.80.80.4-0.6
Bone: trabecular number1.42.215.33.9-1.82.11.4-1.11.21.2-1.2-0.80.8-1.21.21.2-1.2-1.71.2-1.21.2-1.2-0.4-1.21.2
Bone: trabecular spacing0.70.96.5-2.51.8-2.0-1.71.4-0.2-0.20.20.3-0.30.2-0.2-0.20.20.4-0.10.1-0.10.1-0.2-0.10.2
Bone: trabecular thickness1.41.715.53.9-1.92.21.5-1.40.70.7-0.7-0.10.1-0.60.60.6-0.6-1.50.6-0.60.6-0.60.0-1.21.1
Bone: trabecular tissue density6.49.011.6-0.3-2.11.82.1-2.6-3.4-3.43.43.0-3.03.4-3.4-3.43.43.3-3.43.4-3.43.42.92.9-2.8
Water consumed over 24 hours0.60.82.01.4-0.80.91.2-0.60.80.8-0.8-1.41.3-0.70.70.7-0.7-0.60.8-0.80.8-0.8-0.9-0.1-0.6
Number of responses in last shaping day0.10.10.3-0.30.4-0.3-0.00.30.30.3-0.3-0.40.3-0.30.30.3-0.3-0.30.3-0.30.3-0.3-0.5-0.30.0