Hub : Genes

Aldh3b1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Aldh3b1 0.41 0.19 9.3e-06 0.18 0.1 0.2 0.18 4.8e-05 3.0e-03 1.8e-05 3.8e-05
2 Brain gene expression Aldh3b1 0.08 0.06 1.8e-07 0.06 0.04 0.06 0.03 1.5e-06 1.0e-04 5.4e-06 4.7e-04
3 BLA gene expression Aldh3b1 0.1 0.07 2.8e-04 0.05 0.03 0.04 0.03 1.8e-03 8.1e-03 2.7e-03 1.5e-02
4 RMTg mRNA stability Aldh3b1 0.14 0.1 2.9e-03 0.05 0.03 0.01 0.01 2.3e-02 7.1e-02 1.3e-01 1.3e-01
5 pVTA gene expression Aldh3b1 0.15 0.1 2.2e-05 0.11 0.12 0.1 0.11 1.3e-05 1.1e-05 3.8e-05 1.8e-05
6 PL gene expression Aldh3b1 0.06 0.04 8.6e-06 0.03 0.05 0.04 0.03 2.0e-04 3.6e-06 7.2e-05 1.4e-04
7 Adipose gene expression Aldh3b1 0.05 0.04 4.7e-04 0.01 0.01 0.02 0.01 2.4e-02 8.4e-03 2.3e-03 1.1e-02
8 NAcc gene expression Aldh3b1 0.06 0.04 3.5e-07 0.03 0.05 0.05 0.05 4.5e-04 6.4e-07 3.7e-06 1.7e-06
9 Adipose mRNA stability Aldh3b1 0.04 0.03 2.1e-03 0.01 0.02 0.02 0.01 3.8e-02 2.4e-03 2.2e-03 7.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.93.15.60.11.41.41.5-2.0-2.12.0-2.42.1
Area under the delay curve1.11.22.10.30.81.01.0-1.1-1.11.5-1.21.4
BMI with tail0.92.98.3-2.00.30.20.3-1.2-1.42.3-2.22.9
BMI without tail0.40.92.1-1.20.20.10.1-0.7-0.81.2-1.31.5
Body weight0.93.613.8-3.7-2.2-2.3-2.31.31.0-0.20.00.6
Weight adjusted by age0.70.82.5-1.6-1.2-1.2-0.90.70.6-0.40.3-0.1
Bone surface1.22.15.0-1.40.30.30.6-1.3-1.51.8-2.02.2
Bone volume1.32.24.2-0.30.90.91.1-1.6-1.71.8-2.02.0
Breakpoint value in progressive ratio session0.70.72.7-1.6-1.1-1.2-0.80.60.5-0.30.10.0
Number of licking bursts0.00.10.1-0.10.10.10.2-0.3-0.30.2-0.30.3
Context. condit. distance diff. score0.60.71.31.10.91.00.9-0.9-0.90.7-0.60.4
Locomotion velocity, session 10.00.00.00.10.00.0-0.1-0.0-0.10.0-0.10.1
Locomotion distance, session 10.91.22.7-0.40.60.60.6-1.1-1.21.4-1.51.6
Locomotion velocity, session 20.91.13.1-1.8-1.3-1.3-1.30.90.8-0.50.4-0.1
Locomotion distance, session 20.20.31.2-1.1-0.1-0.2-0.2-0.2-0.30.6-0.70.9
Locomotion velocity, session 31.51.72.50.51.21.21.0-1.4-1.41.6-1.61.6
Locomotion distance, session 30.10.10.20.10.30.40.1-0.3-0.30.4-0.40.5
Stereotopy head waving bouts, day 31.82.12.80.91.31.41.7-1.6-1.61.6-1.61.4
Stereotopy head waving duration, day 31.51.82.81.31.41.51.7-1.4-1.41.2-1.21.0
Locomotion velocity, session 71.11.21.80.21.10.90.9-1.2-1.21.3-1.31.3
Locomotion distance, session 70.10.10.3-0.60.0-0.1-0.1-0.1-0.20.3-0.30.4
Stereotopy head waving bouts, day 71.92.22.71.11.51.61.6-1.5-1.51.5-1.51.3
Stereotopy head waving duration, day 71.01.22.4-0.30.70.80.7-1.1-1.21.5-1.51.6
Locomotion velocity, session 80.50.61.7-1.3-1.0-0.9-1.00.60.5-0.30.20.0
Locomotion distance, session 80.40.50.70.50.70.70.6-0.9-0.80.8-0.80.7
Degree of sensitization distance0.20.20.3-0.50.20.10.2-0.3-0.40.5-0.50.6
Degree of sensitization stereotypy0.50.50.9-0.10.40.50.5-0.7-0.80.9-0.90.9
Conditioned locomotion4.14.85.9-2.1-2.4-2.3-2.42.32.2-2.12.0-1.8
Cocaine response after cond. corrected0.10.20.40.60.40.40.4-0.4-0.40.3-0.30.2
Cocaine response after cond. not corrected0.50.60.70.60.80.80.7-0.8-0.80.8-0.80.7
Cocaine response before conditioning0.10.20.4-0.30.30.30.2-0.3-0.40.5-0.50.6
Saline control response0.91.24.0-2.0-1.4-1.4-1.30.80.6-0.30.20.1
Bone: connectivity density1.32.04.6-1.00.50.50.7-1.4-1.61.7-2.22.0
Bone: cortical apparent density0.50.61.1-1.0-0.8-0.9-1.00.80.8-0.60.6-0.4
Bone: cortical area0.91.31.8-1.0-1.3-1.3-1.21.21.1-1.11.0-0.9
Bone: cortical porosity0.10.10.30.30.20.10.2-0.3-0.30.5-0.30.5
Bone: cortical porosity0.10.10.2-0.4-0.4-0.4-0.30.20.20.10.00.3
Bone: cortical thickness5.48.811.5-3.1-3.4-3.4-3.33.02.9-2.72.4-2.2
Bone: cortical thickness2.22.53.8-1.9-1.8-1.8-1.81.61.5-1.51.2-1.2
Bone: cortical tissue density0.60.81.3-1.1-0.9-1.0-1.10.90.8-0.70.6-0.5
Condit. Reinf. active minus inactive responses0.30.40.7-0.10.50.50.3-0.6-0.60.8-0.70.8
Condit. Reinf. active-inactive response ratio0.30.40.50.30.70.60.4-0.6-0.60.7-0.60.7
Condit. Reinf. active responses0.00.10.1-0.00.30.20.1-0.2-0.20.3-0.20.4
Condit. Reinf. inactive responses0.00.00.10.10.0-0.1-0.10.20.2-0.20.3-0.2
Incentive salience index mean0.20.20.5-0.30.20.20.1-0.4-0.40.6-0.60.7
Condit. Reinf. lever presses0.10.10.2-0.5-0.3-0.3-0.40.30.3-0.20.3-0.1
Condit. Reinf. active minus inactive responses2.12.63.11.31.81.71.6-1.7-1.71.7-1.61.5
Condit. Reinf. active-inactive response ratio2.12.23.21.81.71.71.7-1.5-1.41.2-1.21.0
Condit. Reinf. active responses1.92.63.40.71.61.61.5-1.7-1.71.9-1.81.8
Condit. Reinf. inactive responses0.50.61.5-0.70.30.30.2-0.6-0.71.0-1.01.2
Condit. Reinf. lever presses0.40.51.2-0.80.10.10.2-0.6-0.70.9-1.01.1
Condit. Reinf. lever reinforcers received1.72.33.40.41.41.41.3-1.6-1.61.8-1.81.8
Conditioned reinforcement - actives0.20.20.50.40.0-0.2-0.10.40.5-0.50.7-0.7
Conditioned reinforcement - inactives2.32.67.22.72.22.02.0-1.2-1.00.7-0.30.1
Conditioned locomotion1.61.99.43.11.41.51.4-0.3-0.1-0.50.8-1.0
Patch foraging indifference point 0 sec0.30.51.41.20.90.80.8-0.5-0.50.6-0.30.4
Patch foraging indifference point AUC1.51.73.0-1.6-1.7-1.7-1.51.21.2-0.70.9-0.4
Delay disc. indifference point, 0s delay2.12.34.10.41.41.41.3-1.5-1.52.0-1.61.9
Delay disc. indifference point, 16s delay1.11.11.71.31.11.21.3-1.0-0.91.0-0.60.7
Delay disc. indifference point, 2s delay0.91.01.40.60.91.01.2-1.0-1.01.1-0.91.1
Delay disc. indifference point, 24s delay0.30.30.4-0.1-0.6-0.6-0.60.60.6-0.60.6-0.5
Delay disc. indifference point, 4s delay0.40.51.2-0.10.30.40.6-0.6-0.61.0-0.71.1
Delay disc. indifference point, 8s delay0.30.30.70.00.40.50.5-0.5-0.60.8-0.70.8
Indifference point function ln k1.62.27.92.81.91.81.8-1.1-0.90.2-0.3-0.3
Indifference point function log k1.62.27.92.81.91.81.8-1.1-0.90.2-0.3-0.3
Patch foraging total patch changes 0 sec0.10.10.60.80.20.20.20.10.10.00.2-0.2
Patch foraging total patch changes 12 sec0.91.23.4-1.8-1.5-1.5-1.20.90.8-0.20.40.1
Patch foraging total patch changes 18 sec0.10.10.2-0.5-0.2-0.3-0.10.0-0.00.5-0.20.5
Patch foraging total patch changes 24 sec0.91.11.8-1.2-1.3-1.4-1.21.01.0-0.80.8-0.6
Patch foraging total patch changes 6 sec0.20.30.8-0.6-0.0-0.1-0.0-0.3-0.30.8-0.60.9
Patch foraging time to switch 0 sec1.11.73.4-1.30.60.60.6-1.2-1.41.6-1.81.8
Patch foraging water rate 0 sec1.32.14.92.2-0.1-0.1-0.11.01.3-1.72.0-2.1
Patch foraging water rate 12 sec1.62.47.42.70.10.00.20.91.1-1.82.0-2.2
Patch foraging water rate 18 sec0.30.42.11.40.40.40.50.00.1-0.40.5-0.5
Patch foraging water rate 24 sec1.01.42.91.4-0.3-0.3-0.21.01.2-1.51.7-1.7
Patch foraging water rate 6 sec1.11.63.61.0-0.6-0.7-0.41.11.2-1.71.7-1.9
Seeking ratio, delayed vs. immediate footshock0.50.61.00.20.60.60.8-0.9-0.90.9-1.00.8
Distance traveled before self-admin0.00.00.1-0.2-0.2-0.20.1-0.2-0.20.0-0.30.1
Distance traveled after self-admin0.00.10.10.10.30.3-0.1-0.2-0.2-0.3-0.2-0.3
Extensor digitorum longus weight3.312.932.5-5.7-4.4-4.4-4.23.22.9-2.01.8-0.9
Bone: elastic displacement2.32.64.1-0.0-1.3-1.3-1.31.81.8-1.92.0-2.0
Bone: elastic work2.53.34.3-1.5-2.1-2.0-2.01.91.9-1.71.7-1.4
Bone: endosteal estimation2.14.66.02.12.32.32.5-2.2-2.12.1-1.81.9
Bone: endosteal perimeter4.49.111.73.03.23.23.4-3.1-3.02.9-2.62.5
Epididymis fat weight1.33.18.83.02.22.12.2-1.4-1.21.0-0.60.4
Delta time in closed arm before/after self-admin1.11.11.8-1.1-1.3-1.3-1.31.11.0-0.60.8-0.4
Delta time in open arm before/after self-admin0.20.20.50.50.70.50.6-0.5-0.50.3-0.40.3
Diff in mean of infusions in LGA sessions0.50.51.2-0.8-1.0-1.1-0.60.60.6-0.60.4-0.6
Delay discount exponential model param0.80.81.5-0.2-0.6-0.7-0.80.90.9-1.21.0-1.2
Extinction: sum of active levers before priming0.80.83.1-1.8-1.1-1.2-1.00.20.1-0.0-0.40.5
Active lever presses in extinction session 62.42.32.9-1.4-1.6-1.7-1.71.61.6-1.41.4-1.1
Bone: final force0.40.62.8-1.7-1.0-1.0-0.70.30.2-0.1-0.20.2
Bone: final moment0.30.52.3-1.5-1.0-1.0-0.70.30.2-0.1-0.20.2
Food consumed during 24 hour testing period0.10.10.30.4-0.1-0.1-0.00.20.3-0.50.4-0.6
Glucose2.84.25.21.82.32.32.2-2.2-2.12.0-1.91.7
Heart weight1.01.43.11.81.41.41.4-1.1-1.00.9-0.70.5
Delay discount hyperbolic model param0.80.81.6-0.2-0.6-0.7-0.90.90.9-1.31.0-1.3
Intermittent access intake day 1-15 change0.40.41.61.30.20.30.4-0.00.1-0.50.4-0.9
Intermittent access intake escalation0.40.41.81.30.50.60.7-0.4-0.3-0.10.0-0.4
Intermittent access intake escalation 20.20.20.80.90.30.30.2-0.00.1-0.50.3-0.7
Intermitt. access day 1 inactive lever presses1.01.02.21.51.31.41.3-0.8-0.70.6-0.40.5
Intermitt. access day 15 inactive lever presses1.71.93.21.71.71.81.6-1.3-1.20.8-0.90.5
Intermitt. access escalation Index0.40.42.21.50.50.60.7-0.3-0.20.10.2-0.2
Intermittent access day 1 total infusions7.28.412.42.33.53.43.3-2.9-2.82.7-2.52.3
Intermittent access day 15 total infusions5.36.010.93.33.13.03.1-2.2-2.11.6-1.40.9
Intermittent access terminal intake (last 3 days)5.15.68.92.73.02.93.0-2.3-2.11.8-1.61.2
Intermittent access total infusions4.44.97.42.22.72.72.7-2.1-2.02.0-1.71.5
Intermittent access day 1 locomotion4.64.86.41.32.52.42.5-2.1-2.12.3-2.02.2
Intermittent access day 15 total locomotion2.93.15.42.32.12.22.2-1.6-1.51.3-1.00.9
Intermittent access total locomotion6.67.510.82.73.33.23.3-2.7-2.62.5-2.12.0
Intermittent access standard deviation0.20.30.90.90.60.60.6-0.3-0.30.1-0.0-0.3
Left kidney weight0.20.53.21.80.50.40.40.10.2-0.40.7-0.6
Right kidney weight0.30.71.81.3-0.0-0.1-0.20.70.8-0.91.3-1.1
Cocaine induced anxiety0.00.00.00.10.10.1-0.1-0.0-0.0-0.10.0-0.2
Post-drug Anxiety1.21.42.1-1.1-1.3-1.3-1.51.21.1-1.10.9-1.0
Baseline Anxiety1.71.82.9-1.5-1.6-1.6-1.71.31.2-1.10.9-0.8
Tail length1.44.25.0-1.7-2.1-2.1-2.22.12.1-2.21.8-2.1
Length with tail2.17.610.7-3.3-3.2-3.3-3.22.72.6-2.32.0-1.8
Length without tail1.32.95.9-2.4-2.1-2.1-2.11.71.5-1.01.0-0.5
Times rat made contact with spout0.20.30.7-0.40.00.10.1-0.4-0.50.7-0.70.8
Lifetime Intake3.94.47.02.02.62.52.5-2.0-1.91.9-1.61.5
Liver weight, left0.00.10.20.40.20.20.4-0.2-0.1-0.2-0.0-0.3
Liver weight, right0.20.30.60.3-0.4-0.4-0.30.60.7-0.70.8-0.7
Locomotor activity0.20.41.51.20.30.20.30.20.3-0.60.5-0.8
Locomotor testing distance0.30.52.11.50.40.30.50.10.2-0.60.5-0.9
Locomotor testing rearing0.81.22.21.51.21.21.5-1.1-1.00.7-0.80.5
Locomotion in novel chamber3.44.29.43.12.62.62.6-1.9-1.71.0-1.10.4
Locomotion in novel chamber post-restriction1.11.34.32.11.41.41.4-0.9-0.70.5-0.3-0.0
Fecal boli incidents, locomotor time 10.10.10.10.10.30.30.4-0.2-0.10.4-0.10.4
Change in fecal boli incidents, locomotor task0.00.00.1-0.30.00.1-0.1-0.1-0.10.3-0.30.2
Time >=10cm from walls, locomotor time 14.34.36.01.52.42.52.2-2.1-2.12.1-2.01.7
Bouts of movement, locomotor time 11.21.42.0-1.1-1.4-1.4-1.31.21.2-0.81.0-0.7
Total resting periods, locomotor time 10.80.91.3-0.7-1.1-1.1-1.01.01.0-0.80.9-0.7
Rest time, locomotor task time 10.50.51.31.10.20.20.20.40.5-0.80.9-1.2
Distance moved, locomotor task time 10.80.91.50.00.80.70.8-1.0-1.11.1-1.21.2
Vertical activity count, locomotor time 11.21.21.91.21.31.21.4-1.2-1.10.9-0.90.6
Time >=10cm from walls, locomotor time 20.00.00.10.30.00.0-0.10.20.2-0.20.3-0.1
Bouts of movement, locomotor time 20.30.30.6-0.8-0.7-0.6-0.80.60.6-0.20.40.1
Total resting periods, locomotor time 20.10.10.2-0.4-0.3-0.3-0.40.30.20.10.10.4
Rest time, locomotor task time 22.22.54.01.82.02.01.9-1.5-1.51.3-1.20.8
Distance moved, locomotor task time 21.11.32.0-1.1-1.4-1.4-1.21.11.1-1.10.9-0.8
Vertical activity count, locomotor time 22.52.73.7-0.5-1.6-1.7-1.51.71.8-1.91.8-1.8
Light reinforcement 10.10.10.70.80.10.10.3-0.00.1-0.30.4-0.5
Light reinforcement 20.50.63.41.80.80.80.8-0.3-0.2-0.10.4-0.3
Bone: marrow area2.14.66.02.12.32.32.5-2.2-2.12.1-1.81.9
Bone: maximum diameter0.00.00.20.4-0.0-0.00.10.10.1-0.10.2-0.1
Bone: maximum force0.81.43.5-1.20.10.10.4-1.0-1.11.5-1.61.9
Bone: maximum moment0.61.13.0-1.10.10.00.3-0.9-1.01.4-1.41.7
Mean time between licks in bursts0.40.61.0-1.0-0.8-0.9-1.00.70.7-0.60.4-0.3
Mean num. licks in bursts0.10.10.10.20.20.20.2-0.2-0.30.4-0.30.4
Cd content in liver0.30.31.51.20.60.60.6-0.3-0.2-0.00.2-0.2
Co content in liver0.70.81.40.1-0.6-0.6-0.70.91.0-1.11.2-1.2
Cu content in liver0.10.20.3-0.5-0.4-0.4-0.50.50.4-0.30.4-0.2
Fe content in liver0.00.00.1-0.1-0.2-0.3-0.20.10.1-0.10.1-0.0
K content in liver0.80.82.1-0.90.10.10.2-0.7-0.81.2-1.21.4
Mg content in liver3.33.45.50.41.51.51.6-1.9-2.02.3-2.12.4
Mn content in liver0.40.52.3-1.5-0.7-0.7-0.70.40.30.1-0.00.4
Na content in liver0.50.50.7-0.3-0.8-0.8-0.70.70.7-0.90.7-0.9
Rb content in liver3.94.85.91.72.42.42.3-2.2-2.22.3-2.02.1
Se content in liver0.91.11.40.61.01.01.1-1.2-1.21.0-1.20.9
Sr content in liver2.82.63.4-1.8-1.8-1.8-1.81.61.6-1.51.3-1.2
Zn content in liver0.40.51.4-1.2-0.8-0.8-0.80.60.5-0.40.3-0.2
Bone: minimum diameter2.75.05.71.82.22.22.3-2.4-2.32.4-2.22.2
Time in familiar zone, hab. session 10.70.61.00.81.00.90.9-0.8-0.80.7-0.70.6
Time in novel zone, hab. session 10.10.10.1-0.1-0.4-0.3-0.40.30.3-0.30.3-0.3
Total zone transitions, hab. session 10.10.10.8-0.9-0.3-0.2-0.20.0-0.00.2-0.20.5
Total locomotion distance, hab. session 10.40.51.00.70.90.91.0-0.7-0.70.6-0.50.5
Locomotion velocity, hab. session 10.10.10.30.20.40.40.6-0.4-0.30.3-0.30.3
Time in familiar zone, hab. session 21.21.31.7-0.9-1.2-1.3-1.31.21.1-1.11.0-1.0
Time in novel zone, hab. session 21.51.51.80.61.21.21.2-1.3-1.31.3-1.31.3
Total zone transitions, hab. session 22.12.76.1-0.90.91.00.9-1.6-1.82.1-2.22.5
Total locomotion distance, hab. session 21.31.82.60.11.11.21.2-1.4-1.51.5-1.61.6
Locomotion velocity, hab. session 21.52.02.50.51.31.41.4-1.5-1.51.6-1.61.6
Novel to familiar place preference ratio0.30.40.6-0.30.50.50.4-0.6-0.60.7-0.70.8
Novelty place preference0.50.60.80.00.80.70.6-0.8-0.80.9-0.90.8
Time in novel zone, NPP test0.50.60.80.00.80.70.6-0.8-0.80.9-0.90.9
Total zone transitions, NPP test0.50.71.7-1.2-0.1-0.00.1-0.6-0.71.0-1.01.3
Total locomotion distance, NPP test0.40.50.80.00.60.60.7-0.8-0.80.8-0.80.9
Locomotion velocity, NPP test0.20.30.50.00.40.50.6-0.6-0.60.6-0.60.7
Intraocular pressure0.50.81.60.4-0.5-0.6-0.50.90.9-1.11.2-1.3
Delta distance traveled before/after self-admin0.00.00.10.10.20.2-0.20.10.1-0.30.1-0.3
Delta ambulatory time before/after self-admin0.10.10.3-0.2-0.10.0-0.50.30.3-0.60.3-0.5
Parametrial fat weight1.83.64.72.22.02.02.0-2.0-1.91.8-1.51.5
Pavlov. Cond. lever latency0.10.10.60.70.40.20.10.10.2-0.30.3-0.4
Pavlov. Cond. magazine entry latency1.21.62.30.41.11.11.1-1.4-1.41.5-1.41.5
Pavlov. Cond. change in total contacts0.80.91.10.71.01.01.0-1.0-1.01.1-0.90.9
Pavlov. Cond. index score0.00.10.10.00.10.20.2-0.3-0.30.3-0.20.3
Pavlov. Cond. latency score0.10.20.3-0.00.20.30.4-0.5-0.50.5-0.40.5
Pavlov. Cond. lever contacts0.10.10.2-0.5-0.2-0.00.1-0.2-0.30.4-0.30.4
Pavlov. Cond. magazine entry number0.00.00.0-0.1-0.0-0.0-0.10.10.1-0.1-0.00.0
Pavlov. Cond. intertrial magazine entries0.40.51.00.3-0.4-0.4-0.40.70.7-0.90.9-1.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.10.10.10.1-0.2-0.20.3-0.20.3
Pavlov. Cond. response bias0.00.00.10.00.10.10.2-0.3-0.30.3-0.20.2
Pavlov. Cond. lever latency0.00.00.10.2-0.0-0.0-0.10.10.1-0.20.2-0.2
Pavlov. Cond. magazine entry latency0.70.82.6-1.6-0.4-0.4-0.3-0.3-0.50.9-1.01.3
Pavlov. Cond. change in total contacts0.40.61.1-0.30.30.40.5-0.8-0.81.0-1.01.1
Pavlov. Cond. index score0.20.30.9-1.0-0.2-0.20.0-0.3-0.40.6-0.70.8
Pavlov. Cond. latency score0.20.20.7-0.8-0.2-0.20.0-0.3-0.40.6-0.60.7
Pavlov. Cond. lever contacts0.10.10.1-0.3-0.3-0.3-0.30.30.3-0.30.3-0.3
Pavlov. Cond. magazine entry number0.81.03.92.00.40.40.40.30.5-1.01.1-1.4
Pavlov. Cond. intertrial magazine entries0.40.52.21.50.70.80.7-0.3-0.2-0.20.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.3-1.2-0.3-0.3-0.1-0.3-0.40.6-0.70.8
Pavlov. Cond. response bias0.10.20.8-0.9-0.3-0.2-0.2-0.1-0.10.3-0.40.6
Time in closed arm before self-admin0.40.40.80.40.80.90.7-0.6-0.60.5-0.50.5
Time in closed arm after self-admin0.20.20.3-0.4-0.5-0.3-0.40.50.5-0.20.5-0.1
Time in open arm before self-admin0.50.51.0-0.6-0.9-1.0-0.70.60.6-0.70.5-0.6
Time in open arm after self-admin0.10.10.3-0.1-0.2-0.4-0.40.30.3-0.50.3-0.5
Bone: periosteal estimation0.10.30.50.60.50.50.7-0.5-0.50.6-0.40.5
Bone: periosteal perimeter0.50.81.00.70.80.81.0-1.0-1.01.0-0.91.0
Bone: post-yield work8.611.816.21.43.13.13.2-3.7-3.74.0-3.84.0
Progressive ratio test 1 active lever presses0.70.71.91.41.31.11.0-0.4-0.30.4-0.00.1
Progressive ratio test 1 breakpoint0.50.51.51.21.10.90.9-0.3-0.20.20.1-0.1
Progressive ratio test 1 inactive lever presses0.50.51.20.81.10.90.8-0.5-0.50.7-0.30.6
Progressive ratio test 2 active lever presses1.61.74.12.01.91.71.6-1.0-0.90.8-0.40.3
Progressive ratio test 2 breakpoint1.21.44.72.21.71.51.4-0.7-0.50.3-0.0-0.2
Progressive ratio test 2 inactive lever presses5.15.910.73.23.33.03.0-2.1-1.91.7-1.31.1
Incentive Sensitization - Responses0.30.30.60.70.70.70.5-0.4-0.40.4-0.30.2
Incentive Sensitization - Breakpoint0.30.40.70.80.80.90.6-0.5-0.40.4-0.30.1
Sum of active levers in priming session hrs 5-63.53.44.9-0.7-1.7-1.7-1.91.92.0-2.22.0-2.1
Progressive ratio1.71.94.1-1.00.60.60.9-1.4-1.51.7-2.01.9
Food seeking constrained by brief footshock0.10.10.4-0.6-0.4-0.3-0.20.10.1-0.3-0.1-0.2
Seeking ratio, punishment vs. effort1.11.32.80.8-0.6-0.5-0.61.11.2-1.51.6-1.7
Retroperitoneal fat weight2.17.020.54.53.23.23.3-2.2-1.91.2-0.90.4
Reaction time number correct1.01.42.3-0.8-1.4-1.5-1.41.21.2-1.11.1-0.8
Reaction time mean minus median0.30.42.2-1.5-0.0-0.0-0.50.1-0.00.5-0.50.9
Reaction time mean minus median AUC0.40.62.2-1.5-0.6-0.6-1.10.70.6-0.30.30.0
Reaction time num false alarms0.81.21.8-0.2-0.9-0.9-1.11.11.2-1.31.2-1.3
Reaction time num false alarms AUC1.11.52.1-0.9-1.2-1.3-1.51.31.2-1.21.1-1.1
Reaction time trials correct on left1.01.42.3-0.8-1.4-1.5-1.41.21.2-1.11.1-0.8
Reaction time trials on left1.21.72.7-0.9-1.5-1.7-1.51.31.3-1.21.2-0.9
Reaction time mean0.40.61.0-0.11.01.00.7-0.7-0.70.7-0.80.7
Reaction time mean AUC0.60.81.30.11.11.10.8-0.8-0.90.8-0.90.8
Median of all reaction times0.71.01.50.31.21.21.0-1.0-1.01.0-1.00.9
Reaction time omissions0.71.02.8-1.7-1.0-1.1-1.40.90.8-0.40.4-0.0
Reaction time false alarm rate0.30.40.7-0.3-0.5-0.5-0.70.70.7-0.70.6-0.8
Reaction time premature initiation rate1.11.53.6-1.9-1.4-1.5-1.61.11.0-0.80.5-0.4
Reaction time premature initiations2.94.16.4-2.5-2.3-2.5-2.52.01.8-1.61.3-1.0
Std. dev. reaction times0.10.20.6-0.80.50.4-0.1-0.1-0.20.5-0.40.6
Reaction time trials completed1.21.72.7-0.9-1.5-1.7-1.51.31.3-1.21.2-0.9
Reaction time trials AUC0.91.32.1-0.8-1.3-1.4-1.31.11.1-1.01.0-0.8
Run reversals in cocaine runway, females0.90.92.4-0.80.40.40.3-0.8-0.91.2-1.21.5
Run reversals in cocaine runway, males1.31.32.1-0.5-1.0-1.0-1.11.21.2-1.51.1-1.3
Latency to leave start box in cocaine runway1.21.31.80.51.01.11.1-1.3-1.31.3-1.31.2
Latency to leave start box in cocaine runway, F0.70.81.10.20.70.80.7-1.0-1.01.0-1.11.0
Latency to leave start box in cocaine runway, M0.00.00.10.20.20.20.3-0.2-0.20.2-0.20.1
Std. dev. time between licks in bursts1.92.22.7-1.0-1.5-1.5-1.61.61.6-1.61.5-1.4
Total sessions with >9 infusions0.80.91.40.91.21.11.1-0.8-0.80.9-0.60.7
Short access day 1 total inactive lever presses1.71.93.71.91.91.81.7-1.1-1.00.8-0.60.6
Short access day 10 total inactive lever presses0.80.91.81.31.21.21.2-0.9-0.80.3-0.50.3
Short access day 1 total infusions3.03.25.21.82.32.22.1-1.7-1.61.5-1.31.2
Short access day 10 total infusions4.75.36.41.12.52.52.4-2.3-2.32.5-2.32.3
Short access total infusions2.22.54.01.02.01.81.7-1.5-1.51.7-1.41.5
Short access day 1 locomotion2.52.73.71.41.91.81.9-1.6-1.51.6-1.31.4
Short access day 10 total locomotion1.51.62.20.81.41.51.5-1.2-1.21.4-1.11.3
Short access total locomotion1.51.62.10.71.51.41.4-1.1-1.11.4-1.11.4
One hour access (0.3 mA shock)4.04.711.53.42.82.82.7-1.8-1.61.1-0.90.5
Compulsive drug intake3.33.44.9-2.1-2.2-2.2-2.21.91.8-1.41.3-1.0
One hour access (shock baseline)4.45.112.33.52.92.92.8-1.9-1.61.2-0.90.5
Social response proportion0.30.31.2-0.70.10.0-0.2-0.3-0.40.7-0.61.1
Social responses0.40.61.1-0.8-0.9-1.0-1.10.80.7-0.30.6-0.1
Social time0.20.30.8-0.9-0.7-0.7-0.70.40.30.00.10.3
Soleus weight0.72.210.73.31.41.41.6-0.4-0.1-0.50.8-1.1
Bone: stiffness1.11.73.9-0.80.50.50.7-1.3-1.41.7-1.82.0
Tibialis anterior weight7.425.139.4-6.3-5.9-5.9-5.75.04.8-3.83.7-2.7
Time to tail flick, vehicle, before self-admin1.51.52.8-0.30.80.91.4-1.3-1.41.4-1.71.3
Time to tail flick, vehicle, after self-admin0.60.72.6-1.6-0.9-1.0-0.90.30.20.3-0.20.8
Time to tail flick, test, before self-admin2.22.13.20.21.41.31.4-1.5-1.51.7-1.61.8
Time to tail flick, test, after self-admin0.10.10.3-0.6-0.4-0.2-0.40.20.2-0.30.1-0.4
Delta time to tail flick, vehicle, before/after SA0.80.81.8-1.1-1.0-1.1-1.30.80.7-0.00.50.4
Delta time to tail flick, test, before/after SA4.74.25.8-1.2-2.1-1.8-2.12.12.1-2.32.1-2.4
Tibia length0.82.32.8-0.8-1.4-1.5-1.51.71.7-1.71.7-1.5
Ambulatory time before self-admin0.10.10.30.0-0.00.00.3-0.5-0.50.4-0.60.4
Ambulatory time after self-admin1.31.42.10.91.41.41.2-1.4-1.40.9-1.30.8
Bone: tissue strength0.40.40.60.50.40.40.6-0.6-0.60.8-0.50.8
Total heroin consumption1.61.95.8-2.4-1.7-1.6-1.71.21.0-0.50.5-0.2
Bone: trabecular number1.52.44.4-0.11.11.11.2-1.7-1.81.8-2.11.9
Bone: trabecular spacing0.40.51.1-0.1-0.6-0.6-0.50.80.9-0.61.1-0.7
Bone: trabecular thickness2.22.73.31.41.81.81.6-1.8-1.81.4-1.71.2
Bone: trabecular tissue density0.91.25.82.41.11.11.0-0.20.0-0.50.8-1.0
Water consumed over 24 hours0.10.20.5-0.7-0.3-0.3-0.2-0.1-0.20.4-0.50.5
Number of responses in last shaping day0.10.10.50.70.70.40.3-0.1-0.00.00.20.0