Hub : Genes

Rap1gap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Rap1gap2 0.07 0.04 1.1e-09 0.06 0.06 0.06 0.06 8.2e-10 2.1e-09 9.2e-10 1.1e-09
2 PL gene expression Rap1gap2 0.38 0.14 0.0e+00 0.4 0.38 0.39 0.4 1.1e-46 1.4e-43 8.8e-46 1.9e-46
3 PL mRNA stability Rap1gap2 0.08 0.05 6.6e-10 0.1 0.09 0.1 0.1 1.1e-10 2.5e-10 1.2e-10 1.2e-10
4 IC intron excision ratio chr10_59855162_59892814 0.15 0.09 3.7e-05 0.1 0.12 0.06 0.11 8.2e-05 7.7e-06 1.6e-03 2.1e-05
5 IC gene expression Rap1gap2 0.59 0.14 0.0e+00 0.55 0.54 0.56 0.55 2.2e-27 1.0e-26 7.9e-28 4.4e-27
6 IC alternative TSS NM_001401654.1 0.08 0.06 6.0e-03 0.03 0.03 0.01 0.03 1.7e-02 1.4e-02 1.3e-01 1.9e-02
7 BLA gene expression Rap1gap2 0.25 0.12 1.9e-11 0.19 0.18 0.19 0.19 1.4e-10 7.1e-10 2.3e-10 1.5e-10
8 PL isoform ratio NM_001401654.1 0.04 0.03 2.2e-05 0.04 0.04 0.03 0.04 9.8e-06 1.2e-05 2.3e-04 2.7e-05
9 PL intron excision ratio chr10_59855162_59892814 0.07 0.05 1.4e-08 0.06 0.06 0.07 0.07 2.0e-07 3.3e-07 6.7e-08 1.0e-07
10 BLA alternative TSS NM_001401654.1 0.09 0.06 5.7e-04 0.06 0.04 0.03 0.03 6.1e-04 5.0e-03 1.4e-02 8.3e-03
11 BLA isoform ratio NM_001401654.1 0.06 0.04 5.0e-03 0.04 0.02 0.01 0.02 5.2e-03 3.8e-02 7.4e-02 3.4e-02
12 PL alternative TSS NM_001401654.1 0.04 0.03 1.7e-04 0.04 0.04 0.03 0.03 5.2e-05 9.3e-05 5.9e-04 1.4e-04
13 OFC gene expression Rap1gap2 0.67 0.15 1.4e-12 0.43 0.46 0.47 0.45 2.1e-11 2.8e-12 1.3e-12 5.8e-12
14 IL gene expression Rap1gap2 0.81 0.07 2.0e-12 0.31 0.32 0.38 0.16 2.9e-08 2.2e-08 5.4e-10 1.3e-04
15 PL alternative TSS XM_063269050.1 0.07 0.06 3.2e-06 0.04 0.05 0.05 0.05 2.4e-05 3.7e-06 4.5e-06 5.6e-06
16 Adipose isoform ratio XM_008767832.4 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 5.6e-03 2.3e-03 7.9e-03 6.0e-03
17 PL isoform ratio XM_017597290.3 0.04 0.04 2.8e-04 0.04 0.03 0.03 0.03 9.7e-05 2.6e-04 2.9e-04 3.8e-04
18 PL intron excision ratio chr10_59855162_59930611 0.02 0.02 1.9e-03 0.02 0.02 0.01 0.02 5.4e-03 2.7e-03 7.3e-03 6.6e-03
19 Liver gene expression Rap1gap2 0.16 0.1 4.5e-13 0.1 0.1 0.1 0.1 1.2e-11 1.6e-11 9.7e-12 1.2e-11
20 IC isoform ratio XM_017597290.3 0.08 0.06 2.5e-03 0.07 0.07 0.07 0.07 5.5e-04 9.2e-04 4.9e-04 9.9e-04
21 IC alternative TSS XM_063269050.1 0.09 0.06 1.6e-03 0.07 0.07 0.06 0.06 8.2e-04 9.0e-04 1.6e-03 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density3.76.39.42.83.03.02.92.9-3.02.8-3.13.0-2.8-2.8-2.81.92.82.0-2.11.3-1.71.71.71.4
Area under the delay curve0.30.41.8-0.6-0.6-0.6-0.7-0.50.7-0.50.8-0.60.60.60.6-0.4-1.3-0.20.5-0.20.4-0.7-0.2-0.5
BMI with tail1.44.87.12.12.72.72.42.3-2.42.4-2.52.1-2.3-2.3-2.32.12.12.2-2.11.7-1.91.51.61.3
BMI without tail0.51.63.61.51.81.81.61.4-1.91.7-1.71.3-1.5-1.5-1.50.41.10.6-0.5-0.2-0.1-0.2-0.1-0.7
Body weight0.41.74.31.31.51.51.51.4-2.11.4-1.51.3-1.5-1.5-1.5-0.40.8-0.30.2-1.51.0-1.2-0.8-1.8
Weight adjusted by age1.72.53.81.71.91.91.61.4-1.51.7-1.81.7-1.6-1.6-1.61.40.71.9-1.71.7-1.61.31.21.3
Bone surface4.17.510.02.83.23.23.13.0-3.03.1-3.22.9-2.8-2.8-2.82.63.02.5-2.62.0-2.32.12.02.0
Bone volume4.37.810.22.83.23.23.13.1-3.13.1-3.23.0-2.8-2.8-2.82.73.02.6-2.72.1-2.32.12.22.0
Breakpoint value in progressive ratio session0.60.71.60.91.01.01.11.1-1.31.2-1.11.0-1.2-1.2-1.20.30.60.4-0.4-0.1-0.1-0.00.1-0.4
Number of licking bursts0.20.30.9-0.2-0.6-0.6-0.7-0.80.8-0.70.6-0.20.50.50.5-0.9-0.9-0.50.5-0.20.4-0.2-0.7-0.3
Context. condit. distance diff. score1.11.42.61.51.31.31.31.4-1.41.2-1.51.6-1.5-1.5-1.50.41.00.8-0.80.2-0.60.60.70.5
Locomotion velocity, session 11.21.33.21.21.31.31.51.5-1.81.5-1.31.2-1.4-1.4-1.40.81.50.4-0.6-0.2-0.10.40.4-0.2
Locomotion distance, session 10.40.51.10.70.80.80.80.8-0.90.6-0.80.7-0.8-0.8-0.80.81.00.5-0.70.2-0.50.80.30.5
Locomotion velocity, session 20.50.61.10.80.80.80.90.9-1.00.8-0.80.8-0.8-0.8-0.80.81.00.4-0.60.2-0.40.60.60.3
Locomotion distance, session 21.52.12.91.61.71.71.61.7-1.61.5-1.71.6-1.7-1.7-1.71.31.61.2-1.30.7-1.11.31.10.8
Locomotion velocity, session 36.27.09.4-3.0-2.8-2.8-2.8-2.92.7-2.82.9-3.12.92.92.9-2.2-2.6-2.62.5-2.22.3-2.1-2.4-1.8
Locomotion distance, session 30.00.10.3-0.30.10.10.10.1-0.00.10.0-0.2-0.0-0.0-0.00.60.10.2-0.30.2-0.30.3-0.10.5
Stereotopy head waving bouts, day 30.40.51.9-0.3-0.2-0.2-0.6-0.60.4-0.60.3-0.50.50.50.5-1.4-0.4-1.00.9-1.10.9-0.6-0.8-1.0
Stereotopy head waving duration, day 30.20.20.8-0.2-0.3-0.3-0.6-0.70.6-0.80.3-0.40.50.50.5-0.9-0.4-0.50.4-0.30.30.1-0.2-0.2
Locomotion velocity, session 71.71.83.01.01.41.41.51.5-1.41.7-1.41.0-1.2-1.2-1.21.71.31.6-1.51.4-1.41.11.40.9
Locomotion distance, session 73.54.46.12.32.52.52.22.3-2.12.4-2.21.9-2.1-2.1-2.11.81.62.3-2.11.9-2.01.62.01.4
Stereotopy head waving bouts, day 70.40.41.00.71.01.00.70.7-0.80.6-1.00.8-0.8-0.8-0.8-0.20.8-0.0-0.2-0.3-0.00.40.10.0
Stereotopy head waving duration, day 70.70.91.70.91.31.31.01.1-1.10.9-1.31.1-1.1-1.1-1.10.51.20.4-0.70.2-0.50.80.40.5
Locomotion velocity, session 80.50.60.80.90.90.90.70.8-0.70.6-0.90.9-0.9-0.9-0.90.50.80.4-0.60.3-0.50.70.60.9
Locomotion distance, session 81.92.74.82.12.12.11.92.0-2.01.7-2.22.0-2.1-2.1-2.10.51.41.0-1.10.2-0.70.80.90.4
Degree of sensitization distance1.41.53.11.81.61.61.41.4-1.41.5-1.41.3-1.3-1.3-1.30.41.01.2-0.90.8-0.80.51.20.2
Degree of sensitization stereotypy0.60.71.31.01.11.11.01.1-1.10.9-1.11.1-1.0-1.0-1.00.31.00.2-0.5-0.0-0.20.50.30.2
Conditioned locomotion0.50.61.0-0.9-0.9-0.9-0.9-0.91.0-1.01.0-0.80.70.70.7-0.7-0.7-0.80.6-0.40.4-0.0-0.6-0.2
Cocaine response after cond. corrected0.10.10.70.20.10.1-0.1-0.0-0.0-0.1-0.10.10.00.00.0-0.8-0.1-0.50.5-0.60.6-0.4-0.3-0.5
Cocaine response after cond. not corrected0.10.10.20.40.30.30.30.3-0.40.3-0.30.3-0.2-0.2-0.2-0.40.2-0.30.2-0.30.3-0.2-0.1-0.4
Cocaine response before conditioning0.80.91.80.60.90.91.21.2-1.21.3-1.00.9-0.9-0.9-0.91.31.10.9-1.00.9-0.80.70.70.5
Saline control response1.01.32.11.21.21.21.21.1-1.01.2-1.01.0-0.9-0.9-0.91.41.11.3-1.31.3-1.31.11.21.1
Bone: connectivity density5.68.812.73.13.53.53.43.4-3.53.3-3.63.3-3.2-3.2-3.22.43.52.4-2.61.7-2.22.22.01.9
Bone: cortical apparent density0.10.10.3-0.0-0.2-0.2-0.3-0.30.4-0.30.3-0.10.20.20.20.1-0.30.3-0.20.5-0.40.50.40.4
Bone: cortical area1.21.83.0-1.6-1.4-1.4-1.4-1.61.5-1.31.6-1.71.71.71.7-0.7-1.6-0.71.0-0.40.8-1.3-1.0-0.8
Bone: cortical porosity0.20.20.40.70.60.60.50.5-0.60.5-0.70.6-0.6-0.6-0.60.10.40.3-0.30.0-0.20.10.30.1
Bone: cortical porosity0.00.00.10.20.20.20.10.1-0.10.1-0.30.2-0.1-0.1-0.1-0.1-0.10.00.0-0.10.1-0.20.1-0.2
Bone: cortical thickness6.210.312.8-3.5-3.3-3.3-3.4-3.53.4-3.43.4-3.63.63.63.6-2.9-3.4-2.83.0-2.32.7-3.1-2.7-2.4
Bone: cortical thickness2.22.63.8-1.5-1.3-1.3-1.6-1.61.4-1.61.5-1.71.61.61.6-2.0-1.6-1.61.7-1.71.7-1.9-1.6-1.9
Bone: cortical tissue density0.10.10.30.1-0.1-0.1-0.1-0.20.3-0.20.10.00.00.00.00.1-0.20.3-0.30.5-0.40.60.40.4
Condit. Reinf. active minus inactive responses0.60.61.0-1.0-0.9-0.9-0.7-0.70.6-0.60.8-0.91.01.01.0-0.2-0.7-0.80.8-0.70.8-0.8-0.8-0.9
Condit. Reinf. active-inactive response ratio4.44.75.8-2.4-2.2-2.2-2.0-2.01.8-1.92.1-2.32.42.42.4-1.7-2.1-2.22.3-2.02.2-2.4-2.1-2.4
Condit. Reinf. active responses0.20.30.70.50.50.50.60.6-0.60.6-0.50.5-0.5-0.5-0.50.90.60.6-0.60.4-0.50.50.50.2
Condit. Reinf. inactive responses5.87.18.82.82.62.62.52.5-2.22.4-2.52.8-2.8-2.8-2.82.62.52.9-2.92.6-2.93.02.72.7
Incentive salience index mean0.60.81.4-1.1-0.9-0.9-0.6-0.70.5-0.60.7-1.01.01.01.0-0.3-0.5-1.00.9-1.01.0-1.0-1.0-1.2
Condit. Reinf. lever presses0.20.31.3-0.4-0.1-0.10.10.1-0.30.1-0.1-0.30.20.20.2-0.20.2-0.70.6-1.00.8-0.9-0.8-1.1
Condit. Reinf. active minus inactive responses1.21.62.81.31.31.31.31.4-1.31.5-1.31.3-1.2-1.2-1.21.71.01.4-1.31.2-1.20.91.30.9
Condit. Reinf. active-inactive response ratio0.00.00.20.1-0.0-0.00.00.1-0.10.1-0.00.1-0.0-0.0-0.00.0-0.2-0.10.2-0.20.2-0.40.0-0.3
Condit. Reinf. active responses3.04.27.71.91.91.92.12.1-1.92.2-1.91.9-1.8-1.8-1.82.81.72.4-2.32.4-2.21.82.11.9
Condit. Reinf. inactive responses5.36.811.52.32.42.42.52.4-2.22.5-2.32.2-2.1-2.1-2.13.42.43.1-3.13.3-3.12.92.62.8
Condit. Reinf. lever presses0.50.72.40.20.20.20.40.5-0.10.5-0.40.4-0.4-0.4-0.41.40.41.1-1.01.6-1.31.21.31.4
Condit. Reinf. lever reinforcers received3.24.48.41.91.91.92.12.1-1.82.2-1.91.9-1.8-1.8-1.82.91.72.6-2.42.5-2.31.92.22.0
Conditioned reinforcement - actives1.93.35.32.01.91.92.01.9-1.92.0-1.61.7-1.5-1.5-1.52.32.02.0-1.91.8-1.81.71.71.3
Conditioned reinforcement - inactives0.81.22.01.41.11.11.21.0-1.11.3-1.01.1-1.2-1.2-1.21.30.51.3-1.11.2-1.10.90.90.5
Conditioned locomotion0.10.10.7-0.2-0.0-0.0-0.2-0.40.5-0.20.2-0.30.40.40.40.40.10.4-0.20.8-0.50.20.20.3
Patch foraging indifference point 0 sec0.10.20.50.10.40.40.50.6-0.50.5-0.60.3-0.4-0.4-0.40.40.70.3-0.40.4-0.30.50.20.5
Patch foraging indifference point AUC0.20.31.20.60.40.40.20.10.00.2-0.20.4-0.3-0.3-0.30.7-0.10.8-0.70.9-0.80.70.71.1
Delay disc. indifference point, 0s delay0.40.40.80.30.50.50.70.8-0.70.9-0.50.5-0.6-0.6-0.60.90.70.7-0.70.6-0.60.40.70.7
Delay disc. indifference point, 16s delay0.20.21.8-0.2-0.1-0.1-0.4-0.30.6-0.10.3-0.20.30.30.3-0.2-1.40.30.10.4-0.0-0.50.4-0.4
Delay disc. indifference point, 2s delay0.30.41.6-0.5-0.8-0.8-0.7-0.60.7-0.60.6-0.50.50.50.5-0.6-1.3-0.40.6-0.40.5-0.60.1-0.5
Delay disc. indifference point, 24s delay0.00.00.5-0.10.00.0-0.00.00.10.2-0.00.2-0.1-0.1-0.10.1-0.70.4-0.10.4-0.2-0.20.1-0.2
Delay disc. indifference point, 4s delay0.20.21.3-0.1-0.3-0.3-0.4-0.30.4-0.30.3-0.30.30.30.3-0.5-1.2-0.30.5-0.40.6-0.8-0.2-0.6
Delay disc. indifference point, 8s delay0.30.31.0-0.5-0.6-0.6-0.6-0.50.6-0.40.8-0.60.50.50.5-0.5-1.0-0.40.5-0.40.5-0.7-0.3-0.5
Indifference point function ln k0.20.41.40.50.60.60.80.9-1.00.8-0.60.4-0.6-0.6-0.60.21.20.1-0.4-0.1-0.10.30.10.0
Indifference point function log k0.20.41.40.50.60.60.80.9-1.00.8-0.60.4-0.6-0.6-0.60.21.20.1-0.4-0.1-0.10.30.10.0
Patch foraging total patch changes 0 sec0.20.30.80.20.50.50.60.7-0.60.6-0.60.4-0.5-0.5-0.50.50.90.4-0.50.5-0.50.60.30.7
Patch foraging total patch changes 12 sec0.70.91.2-1.1-1.0-1.0-1.0-1.00.9-1.00.9-1.01.11.11.1-0.7-1.1-1.00.9-0.90.9-0.8-1.0-0.5
Patch foraging total patch changes 18 sec0.20.30.7-0.4-0.5-0.5-0.6-0.60.6-0.70.3-0.30.30.30.3-0.6-0.8-0.40.5-0.40.5-0.8-0.5-0.2
Patch foraging total patch changes 24 sec0.20.40.9-0.9-0.7-0.7-0.7-0.70.8-0.70.6-0.60.60.60.6-0.3-1.0-0.40.5-0.20.3-0.5-0.4-0.2
Patch foraging total patch changes 6 sec0.10.21.1-0.1-0.0-0.0-0.00.00.20.0-0.10.10.00.00.00.60.10.4-0.40.8-0.60.60.31.0
Patch foraging time to switch 0 sec1.63.25.4-1.8-1.7-1.7-1.8-1.71.6-1.81.4-1.31.31.31.3-2.3-1.8-2.12.1-2.02.1-2.1-1.5-2.2
Patch foraging water rate 0 sec0.40.92.90.70.60.60.80.7-0.60.8-0.40.3-0.3-0.3-0.31.71.01.2-1.31.4-1.31.50.81.5
Patch foraging water rate 12 sec0.10.10.50.50.20.20.50.5-0.50.6-0.10.1-0.3-0.3-0.30.70.30.5-0.40.2-0.30.10.10.0
Patch foraging water rate 18 sec2.74.26.12.22.12.12.42.3-2.42.5-1.81.8-1.8-1.8-1.82.52.42.0-2.11.6-1.82.11.51.5
Patch foraging water rate 24 sec0.30.42.00.10.20.20.60.4-0.50.5-0.10.00.00.00.01.40.80.7-0.80.8-0.81.00.30.7
Patch foraging water rate 6 sec0.10.10.2-0.2-0.3-0.3-0.2-0.30.3-0.20.3-0.40.40.40.40.3-0.10.2-0.20.4-0.30.3-0.10.2
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.2-0.2-0.2-0.6-0.40.8-0.60.3-0.30.40.40.4-0.1-0.90.10.00.3-0.20.20.20.7
Distance traveled before self-admin1.41.85.8-1.3-1.5-1.5-1.7-1.31.9-1.51.6-1.51.31.31.3-1.2-2.4-0.81.1-0.30.7-0.90.1-0.6
Distance traveled after self-admin0.10.10.7-0.1-0.2-0.2-0.4-0.30.4-0.20.5-0.50.50.50.5-0.2-0.90.00.20.20.1-0.30.0-0.5
Extensor digitorum longus weight5.421.226.44.95.15.14.94.8-4.84.7-5.04.7-4.7-4.7-4.74.65.14.2-4.63.6-4.24.43.83.8
Bone: elastic displacement0.20.30.6-0.6-0.6-0.6-0.6-0.70.8-0.70.6-0.50.70.70.7-0.0-0.5-0.10.20.0-0.1-0.0-0.20.3
Bone: elastic work6.28.111.2-3.3-2.9-2.9-3.0-3.23.1-3.12.9-3.33.33.33.3-2.3-2.8-2.52.6-2.02.2-2.4-2.8-1.8
Bone: endosteal estimation0.51.02.00.91.01.01.00.8-0.91.1-0.80.9-0.8-0.8-0.81.40.61.2-1.11.4-1.11.11.00.9
Bone: endosteal perimeter2.34.98.62.12.12.12.22.1-1.92.3-1.92.0-1.9-1.9-1.92.91.82.7-2.52.5-2.52.22.12.2
Epididymis fat weight7.023.936.75.95.65.65.75.7-6.15.6-5.85.8-6.0-6.0-6.03.34.83.9-3.92.2-2.92.73.31.6
Delta time in closed arm before/after self-admin0.20.10.70.1-0.3-0.3-0.3-0.20.4-0.2-0.10.3-0.3-0.3-0.3-0.1-0.80.2-0.20.4-0.30.60.20.8
Delta time in open arm before/after self-admin0.60.61.10.61.01.00.90.9-1.00.8-1.00.8-0.8-0.8-0.80.61.00.6-0.60.3-0.50.10.50.2
Diff in mean of infusions in LGA sessions0.40.41.10.80.70.70.90.8-1.10.8-0.90.7-0.8-0.8-0.80.30.90.1-0.2-0.40.10.1-0.3-0.0
Delay discount exponential model param0.30.31.60.60.60.60.60.5-0.70.4-0.70.6-0.6-0.6-0.60.41.30.3-0.50.2-0.40.70.30.5
Extinction: sum of active levers before priming4.65.16.92.42.42.42.52.3-2.42.4-2.62.4-2.6-2.6-2.62.22.02.3-2.21.7-2.01.91.61.4
Active lever presses in extinction session 63.43.44.52.02.12.12.12.1-2.12.1-1.91.8-2.0-2.0-2.01.71.91.7-1.71.2-1.41.51.41.3
Bone: final force1.82.84.7-2.2-1.4-1.4-1.5-1.61.4-1.41.4-2.01.71.71.7-1.6-1.4-1.71.8-1.51.7-2.0-2.1-1.7
Bone: final moment1.52.34.2-2.1-1.3-1.3-1.4-1.51.3-1.31.2-1.91.71.71.7-1.4-1.2-1.61.6-1.21.5-1.8-1.9-1.4
Food consumed during 24 hour testing period0.30.40.90.60.70.70.70.8-0.70.7-1.00.8-0.8-0.8-0.80.40.60.4-0.50.1-0.40.30.40.4
Glucose2.43.76.1-2.3-2.4-2.4-2.3-2.32.5-2.22.3-2.12.12.12.1-1.1-2.4-1.31.5-0.81.1-1.4-1.2-0.7
Heart weight0.40.61.40.71.01.00.80.8-1.00.6-1.20.8-1.0-1.0-1.0-0.30.9-0.2-0.0-0.60.3-0.3-0.4-0.3
Delay discount hyperbolic model param0.50.62.00.70.80.80.80.7-0.80.6-0.90.8-0.8-0.8-0.80.61.40.5-0.70.4-0.60.90.50.7
Intermittent access intake day 1-15 change0.40.82.90.20.10.10.20.40.10.3-0.40.7-0.6-0.6-0.61.40.11.3-1.11.7-1.41.11.51.4
Intermittent access intake escalation0.51.03.50.20.20.20.30.50.10.4-0.50.7-0.5-0.5-0.51.60.11.5-1.21.9-1.61.21.61.5
Intermittent access intake escalation 20.40.41.9-0.3-0.4-0.4-0.2-0.00.6-0.20.20.2-0.0-0.0-0.00.9-0.10.8-0.71.3-1.00.91.11.4
Intermitt. access day 1 inactive lever presses0.20.82.1-0.8-0.7-0.7-0.9-0.91.2-0.61.3-1.41.41.41.40.6-0.70.10.00.7-0.30.20.00.7
Intermitt. access day 15 inactive lever presses0.20.31.30.30.20.2-0.2-0.10.50.10.10.2-0.2-0.2-0.20.3-0.90.8-0.51.1-0.80.80.71.0
Intermitt. access escalation Index0.60.82.7-0.4-0.4-0.4-0.4-0.50.1-0.60.1-0.20.10.10.1-1.6-0.3-1.31.2-1.61.4-1.4-1.0-1.6
Intermittent access day 1 total infusions0.20.30.70.80.80.80.60.6-0.50.8-0.50.6-0.5-0.5-0.50.6-0.20.8-0.60.7-0.50.30.90.0
Intermittent access day 15 total infusions1.42.14.31.11.21.21.21.3-0.91.3-1.31.4-1.2-1.2-1.21.90.61.9-1.72.1-1.81.41.91.4
Intermittent access terminal intake (last 3 days)1.72.23.91.41.41.41.41.6-1.21.4-1.31.5-1.4-1.4-1.41.81.21.7-1.61.7-1.61.42.01.4
Intermittent access total infusions1.41.63.41.21.21.21.11.3-0.91.3-1.21.2-1.1-1.1-1.11.50.31.6-1.41.7-1.41.11.81.0
Intermittent access day 1 locomotion0.10.10.40.10.30.30.10.0-0.10.40.1-0.40.30.30.30.3-0.70.20.00.20.1-0.3-0.1-0.6
Intermittent access day 15 total locomotion0.10.21.10.20.30.30.20.10.00.3-0.10.1-0.0-0.0-0.01.0-0.40.9-0.61.1-0.70.40.70.3
Intermittent access total locomotion0.40.51.60.50.70.70.60.6-0.50.9-0.50.5-0.5-0.5-0.51.3-0.21.1-0.91.2-0.90.60.90.4
Intermittent access standard deviation1.53.27.91.41.41.41.31.4-0.81.5-1.21.4-1.2-1.2-1.22.50.92.4-2.22.8-2.52.22.12.5
Left kidney weight2.411.015.5-3.2-3.0-3.0-3.3-3.43.0-3.32.9-3.13.03.03.0-3.9-3.7-3.43.6-3.33.5-3.8-3.2-3.6
Right kidney weight2.19.614.5-2.7-2.6-2.6-2.9-3.02.5-2.92.6-2.82.72.72.7-3.8-3.5-3.43.5-3.53.5-3.8-3.0-3.8
Cocaine induced anxiety0.10.10.3-0.1-0.3-0.3-0.3-0.20.4-0.30.4-0.30.60.60.60.20.1-0.10.00.1-0.10.20.20.5
Post-drug Anxiety0.20.21.0-0.1-0.4-0.4-0.2-0.1-0.0-0.40.4-0.40.50.50.5-0.50.5-0.90.6-1.00.8-0.4-0.0-0.4
Baseline Anxiety0.20.20.60.30.30.30.50.5-0.70.4-0.50.4-0.6-0.6-0.6-0.40.7-0.30.2-0.70.5-0.30.1-0.6
Tail length0.62.49.1-0.3-0.4-0.4-0.2-0.2-0.4-0.20.3-0.30.20.20.2-2.2-0.5-2.22.0-3.02.6-2.5-2.2-2.8
Length with tail0.94.113.6-0.8-1.1-1.1-0.8-0.70.1-0.80.9-0.80.70.70.7-2.9-1.2-2.82.6-3.73.2-3.1-2.6-3.6
Length without tail0.10.52.10.2-0.1-0.10.30.4-0.70.3-0.10.2-0.3-0.3-0.3-0.70.0-0.90.8-1.51.2-1.1-0.7-1.4
Times rat made contact with spout2.22.53.7-1.8-1.5-1.5-1.4-1.51.3-1.31.6-1.91.91.91.9-1.4-1.3-1.51.6-1.51.6-1.8-1.5-1.6
Lifetime Intake1.11.32.41.11.21.21.11.2-0.91.3-1.01.1-0.9-0.9-0.91.50.31.5-1.31.5-1.31.01.50.9
Liver weight, left1.01.68.20.90.70.70.80.8-1.40.7-0.70.6-0.8-0.8-0.8-1.50.0-1.11.1-2.31.8-1.8-1.0-2.9
Liver weight, right1.01.73.61.51.51.51.41.5-1.91.5-1.41.2-1.6-1.6-1.6-0.90.6-0.40.3-1.51.0-1.0-0.4-1.8
Locomotor activity0.40.71.31.11.01.00.80.8-0.70.9-0.80.9-1.0-1.0-1.00.60.11.1-0.70.9-0.70.30.90.2
Locomotor testing distance0.10.20.50.60.50.50.30.3-0.30.3-0.40.5-0.5-0.5-0.50.10.20.5-0.30.5-0.40.20.70.1
Locomotor testing rearing0.91.73.31.41.21.21.21.2-1.01.1-1.21.4-1.2-1.2-1.21.21.11.6-1.51.7-1.61.31.81.3
Locomotion in novel chamber0.60.83.9-0.4-0.3-0.3-0.30.00.7-0.30.2-0.20.30.30.31.0-0.31.0-0.91.6-1.31.32.01.7
Locomotion in novel chamber post-restriction0.40.61.40.40.70.70.60.8-0.50.5-0.90.8-0.9-0.9-0.90.60.90.6-0.80.9-0.81.01.11.2
Fecal boli incidents, locomotor time 10.30.40.8-0.7-0.6-0.6-0.6-0.50.5-0.70.5-0.60.70.70.7-0.7-0.1-0.90.7-0.80.7-0.4-0.5-0.3
Change in fecal boli incidents, locomotor task0.70.70.8-0.8-0.8-0.8-0.8-0.90.8-0.80.7-0.70.80.80.8-0.9-0.8-0.80.9-0.80.8-0.9-0.9-0.7
Time >=10cm from walls, locomotor time 10.10.10.50.10.40.40.30.2-0.30.3-0.50.10.00.00.00.50.70.2-0.40.4-0.40.4-0.00.4
Bouts of movement, locomotor time 10.00.00.2-0.10.10.10.20.3-0.30.2-0.2-0.0-0.1-0.1-0.10.20.4-0.1-0.1-0.20.00.2-0.10.1
Total resting periods, locomotor time 10.10.10.20.10.20.20.30.3-0.30.3-0.30.1-0.2-0.2-0.20.30.40.1-0.2-0.0-0.20.4-0.00.4
Rest time, locomotor task time 10.20.20.4-0.5-0.6-0.6-0.5-0.40.6-0.50.6-0.40.60.60.60.0-0.5-0.30.2-0.10.00.2-0.10.2
Distance moved, locomotor task time 10.20.30.50.60.60.60.60.5-0.50.5-0.70.6-0.6-0.6-0.60.50.30.6-0.50.4-0.50.30.40.2
Vertical activity count, locomotor time 10.30.81.30.80.90.91.00.9-1.00.8-1.10.8-0.8-0.8-0.80.81.10.8-0.90.7-0.80.80.80.7
Time >=10cm from walls, locomotor time 20.30.41.0-0.9-0.3-0.3-0.6-0.60.6-0.40.4-1.01.01.01.0-0.4-0.8-0.40.5-0.20.4-0.7-0.8-0.4
Bouts of movement, locomotor time 20.00.00.10.0-0.0-0.00.10.2-0.10.20.2-0.10.10.10.10.2-0.20.1-0.00.00.0-0.20.2-0.2
Total resting periods, locomotor time 20.10.10.30.30.30.30.40.5-0.40.5-0.10.2-0.1-0.1-0.10.50.30.4-0.30.3-0.20.00.2-0.0
Rest time, locomotor task time 20.30.40.91.00.50.50.50.5-0.40.6-0.40.9-0.6-0.6-0.60.70.10.9-0.70.8-0.70.60.80.5
Distance moved, locomotor task time 20.10.10.5-0.1-0.1-0.1-0.0-0.00.1-0.1-0.0-0.00.00.00.00.50.30.2-0.30.3-0.40.50.20.7
Vertical activity count, locomotor time 20.40.51.0-0.9-0.8-0.8-0.7-0.70.7-0.90.6-0.80.80.80.8-0.8-0.1-1.00.8-0.90.7-0.4-0.6-0.2
Light reinforcement 10.00.10.40.10.00.00.20.3-0.10.2-0.30.5-0.4-0.4-0.40.30.20.3-0.30.3-0.30.30.60.2
Light reinforcement 22.43.74.5-1.8-1.9-1.9-2.0-2.02.0-2.02.1-2.02.02.02.0-2.1-2.1-1.82.0-1.51.8-1.8-1.5-1.8
Bone: marrow area0.40.91.90.90.90.90.90.8-0.81.0-0.80.8-0.8-0.8-0.81.40.61.1-1.11.3-1.11.00.90.8
Bone: maximum diameter0.50.82.70.50.70.70.70.6-0.50.8-0.60.5-0.4-0.4-0.41.60.51.4-1.21.6-1.31.00.91.2
Bone: maximum force1.62.84.1-2.0-1.4-1.4-1.6-1.71.5-1.51.4-1.91.81.81.8-1.6-1.6-1.71.7-1.41.6-1.9-1.9-1.6
Bone: maximum moment1.32.33.6-1.9-1.3-1.3-1.5-1.61.4-1.41.3-1.81.71.71.7-1.4-1.4-1.41.5-1.11.4-1.6-1.6-1.3
Mean time between licks in bursts0.10.21.1-0.0-0.1-0.1-0.1-0.1-0.1-0.10.2-0.20.10.10.1-0.7-0.1-0.70.6-1.00.8-0.6-0.5-1.0
Mean num. licks in bursts0.30.51.2-1.0-0.5-0.5-0.3-0.30.2-0.20.5-1.10.80.80.8-0.10.0-0.60.6-0.80.7-1.1-0.5-0.8
Cd content in liver2.93.35.12.31.71.71.61.6-1.41.6-1.62.0-1.8-1.8-1.81.81.12.2-2.02.1-2.01.82.11.7
Co content in liver0.00.10.3-0.20.00.00.0-0.10.10.30.3-0.40.20.20.20.5-0.00.3-0.10.4-0.1-0.20.0-0.2
Cu content in liver0.70.91.5-1.2-1.2-1.2-1.0-1.21.1-0.91.1-1.10.90.90.9-0.3-1.2-0.60.7-0.30.6-0.7-1.2-0.7
Fe content in liver0.30.31.1-0.1-0.2-0.2-0.2-0.30.0-0.30.2-0.20.00.00.0-0.8-0.2-0.80.8-1.10.9-0.8-1.0-1.0
K content in liver1.11.13.9-1.3-0.8-0.8-0.7-0.80.4-0.50.8-1.10.80.80.8-0.6-0.5-1.21.1-1.31.3-1.4-2.0-1.4
Mg content in liver0.30.31.40.20.40.40.60.4-0.50.7-0.40.2-0.3-0.3-0.31.20.70.7-0.70.7-0.70.60.00.6
Mn content in liver0.50.51.10.40.50.50.60.5-0.50.5-0.70.8-1.0-1.0-1.00.60.90.6-0.80.6-0.81.00.21.0
Na content in liver2.72.94.2-1.9-1.8-1.8-1.7-1.81.7-1.51.9-2.01.91.91.9-1.4-1.8-1.41.6-1.21.5-1.7-1.5-1.5
Rb content in liver5.56.48.22.62.72.72.62.6-2.52.6-2.62.6-2.9-2.9-2.92.52.52.5-2.52.2-2.32.31.62.0
Se content in liver0.70.92.0-1.2-1.1-1.1-0.9-1.10.9-0.81.1-1.10.90.90.9-0.3-0.8-0.80.8-0.60.7-0.7-1.4-0.6
Sr content in liver1.61.41.91.21.21.21.21.1-1.11.1-1.21.2-1.4-1.4-1.41.21.31.1-1.21.0-1.11.31.01.2
Zn content in liver0.10.11.1-0.2-0.1-0.10.1-0.1-0.20.20.1-0.10.10.10.10.10.2-0.20.2-0.40.3-0.3-1.1-0.5
Bone: minimum diameter0.50.92.0-0.7-0.7-0.7-0.9-1.00.9-0.81.1-1.01.11.11.1-0.9-1.4-0.60.9-0.60.9-1.2-0.7-1.1
Time in familiar zone, hab. session 11.81.72.81.21.21.21.11.2-0.91.2-1.21.3-1.3-1.3-1.31.40.91.4-1.51.6-1.51.71.31.6
Time in novel zone, hab. session 11.21.22.5-0.8-0.9-0.9-1.0-0.90.8-0.91.0-0.91.01.01.0-1.5-1.1-1.21.3-1.21.3-1.4-0.8-1.6
Total zone transitions, hab. session 13.24.45.82.32.02.02.02.1-1.92.0-2.12.2-2.1-2.1-2.12.01.82.2-2.22.1-2.22.42.32.1
Total locomotion distance, hab. session 10.91.32.11.51.21.21.11.1-1.11.1-1.01.2-1.1-1.1-1.10.91.01.1-1.10.9-1.01.31.21.0
Locomotion velocity, hab. session 10.81.21.81.31.11.11.11.1-1.01.0-1.01.1-1.0-1.0-1.01.01.11.1-1.11.0-1.11.31.11.1
Time in familiar zone, hab. session 22.52.63.41.81.71.71.71.6-1.61.6-1.71.7-1.7-1.7-1.71.51.61.6-1.71.5-1.61.71.41.4
Time in novel zone, hab. session 25.75.86.7-2.6-2.4-2.4-2.5-2.42.4-2.42.5-2.62.52.52.5-2.3-2.4-2.42.5-2.12.3-2.5-2.0-2.1
Total zone transitions, hab. session 20.91.22.01.21.21.21.21.2-1.20.9-1.31.3-1.4-1.4-1.40.61.30.7-0.90.3-0.71.00.70.7
Total locomotion distance, hab. session 20.00.10.3-0.1-0.1-0.1-0.1-0.2-0.0-0.30.1-0.00.00.00.0-0.50.2-0.40.3-0.60.4-0.0-0.4-0.3
Locomotion velocity, hab. session 20.10.10.3-0.1-0.2-0.2-0.2-0.30.1-0.40.2-0.10.10.10.1-0.40.1-0.50.3-0.50.4-0.1-0.4-0.3
Novel to familiar place preference ratio0.10.20.7-0.30.00.00.10.10.10.30.2-0.1-0.0-0.0-0.00.80.30.6-0.50.8-0.60.30.50.7
Novelty place preference0.00.00.2-0.30.00.00.00.10.00.20.2-0.20.00.00.00.50.20.3-0.20.4-0.3-0.00.20.3
Time in novel zone, NPP test0.10.10.3-0.00.30.30.30.3-0.20.4-0.00.1-0.2-0.2-0.20.50.40.4-0.40.4-0.40.10.30.3
Total zone transitions, NPP test1.72.53.11.71.71.71.51.5-1.41.3-1.71.8-1.8-1.8-1.81.31.41.5-1.61.3-1.51.71.51.5
Total locomotion distance, NPP test0.50.71.50.90.80.80.70.5-0.50.5-0.70.8-0.6-0.6-0.60.70.71.0-1.01.0-1.01.21.01.1
Locomotion velocity, NPP test0.30.41.30.50.40.40.30.2-0.10.1-0.30.5-0.3-0.3-0.30.60.40.8-0.81.0-1.01.10.81.1
Intraocular pressure1.82.66.51.10.80.81.11.1-0.71.3-1.01.3-1.3-1.3-1.32.10.92.4-2.02.6-2.32.02.12.2
Delta distance traveled before/after self-admin1.21.32.71.31.51.51.51.2-1.61.5-1.31.1-1.1-1.1-1.10.91.60.8-0.90.4-0.60.6-0.00.2
Delta ambulatory time before/after self-admin0.81.02.31.11.31.31.31.1-1.51.3-1.31.1-1.0-1.0-1.00.81.50.6-0.80.3-0.50.60.00.1
Parametrial fat weight4.310.017.83.53.63.63.83.9-4.23.7-3.93.9-4.0-4.0-4.01.73.61.9-2.10.7-1.31.42.00.3
Pavlov. Cond. lever latency0.40.51.20.40.40.40.50.6-0.40.5-0.40.6-0.6-0.6-0.60.80.60.7-0.80.9-0.91.10.71.0
Pavlov. Cond. magazine entry latency0.20.31.0-0.3-0.1-0.1-0.1-0.2-0.1-0.2-0.1-0.20.10.10.1-0.5-0.3-0.70.6-0.90.8-0.8-0.7-1.0
Pavlov. Cond. change in total contacts0.60.61.6-0.7-0.8-0.8-0.9-0.90.9-1.00.7-0.70.80.80.8-0.8-1.3-0.70.8-0.70.7-0.7-0.6-0.8
Pavlov. Cond. index score0.30.41.3-0.3-0.1-0.1-0.2-0.2-0.0-0.2-0.0-0.30.20.20.2-0.8-0.3-0.90.8-1.11.0-1.0-0.9-1.2
Pavlov. Cond. latency score0.50.62.0-0.4-0.2-0.2-0.4-0.40.1-0.40.1-0.50.40.40.4-1.1-0.4-1.11.0-1.41.2-1.3-1.1-1.4
Pavlov. Cond. lever contacts0.30.41.1-0.5-0.4-0.4-0.5-0.50.3-0.40.3-0.60.50.50.5-0.6-0.6-0.70.8-0.80.8-1.1-0.6-0.9
Pavlov. Cond. magazine entry number0.00.00.1-0.0-0.1-0.1-0.00.00.10.10.3-0.10.10.10.10.30.20.3-0.20.4-0.30.20.30.4
Pavlov. Cond. intertrial magazine entries1.21.42.61.10.80.80.91.0-0.70.9-0.81.1-1.0-1.0-1.01.50.81.4-1.41.5-1.51.61.51.6
Pavlov. Cond. lever-magazine prob. diff.0.20.31.1-0.3-0.1-0.1-0.2-0.20.0-0.2-0.0-0.30.20.20.2-0.7-0.3-0.80.7-1.00.9-0.8-0.8-1.0
Pavlov. Cond. response bias0.10.10.4-0.00.10.10.0-0.0-0.2-0.0-0.20.0-0.0-0.0-0.0-0.3-0.1-0.40.4-0.60.5-0.5-0.3-0.7
Pavlov. Cond. lever latency0.30.41.20.60.80.80.90.8-1.10.8-0.80.6-0.6-0.6-0.60.31.10.1-0.3-0.4-0.00.3-0.3-0.2
Pavlov. Cond. magazine entry latency1.31.62.7-1.3-1.3-1.3-1.4-1.21.3-1.21.2-1.21.21.21.2-1.2-1.6-1.31.4-1.11.3-1.4-0.9-1.1
Pavlov. Cond. change in total contacts0.40.71.2-1.1-1.0-1.0-1.0-0.91.1-0.81.0-1.11.01.01.0-0.4-1.0-0.50.6-0.20.4-0.7-0.5-0.3
Pavlov. Cond. index score0.60.81.9-1.0-1.1-1.1-1.2-1.01.3-1.01.1-0.90.90.90.9-0.4-1.4-0.30.60.10.3-0.60.1-0.1
Pavlov. Cond. latency score0.70.92.2-1.1-1.2-1.2-1.3-1.11.5-1.11.2-1.01.01.01.0-0.5-1.5-0.40.60.10.3-0.60.0-0.1
Pavlov. Cond. lever contacts0.20.30.8-0.5-0.7-0.7-0.7-0.60.8-0.60.6-0.50.50.50.5-0.3-0.9-0.20.40.10.2-0.50.2-0.1
Pavlov. Cond. magazine entry number1.31.62.41.51.41.41.41.3-1.41.3-1.31.3-1.2-1.2-1.21.11.61.2-1.31.0-1.21.40.91.0
Pavlov. Cond. intertrial magazine entries2.33.44.42.12.02.02.11.9-2.02.0-1.71.8-1.7-1.7-1.72.12.01.9-1.91.6-1.71.91.61.3
Pavlov. Cond. lever-magazine prob. diff.0.50.71.7-1.0-1.1-1.1-1.1-1.01.3-1.01.0-0.90.80.80.8-0.5-1.3-0.30.60.10.3-0.50.1-0.1
Pavlov. Cond. response bias0.50.61.6-0.8-0.9-0.9-1.0-0.91.1-0.90.9-0.80.70.70.7-0.7-1.3-0.50.7-0.20.5-0.9-0.1-0.4
Time in closed arm before self-admin0.20.31.40.20.30.30.40.5-0.70.3-0.30.2-0.3-0.3-0.3-0.41.2-0.70.3-1.00.6-0.2-0.4-0.7
Time in closed arm after self-admin0.70.81.4-0.7-1.1-1.1-0.9-0.80.8-1.00.8-0.80.70.70.7-1.0-0.9-1.21.0-1.21.0-0.5-0.8-0.6
Time in open arm before self-admin1.21.35.1-1.0-1.1-1.1-1.5-1.41.7-1.21.3-1.21.31.31.3-1.0-2.2-0.30.80.20.4-0.8-0.2-0.4
Time in open arm after self-admin0.20.31.5-0.00.40.4-0.0-0.10.30.1-0.50.3-0.2-0.2-0.20.2-0.71.0-0.51.2-0.8-0.00.60.5
Bone: periosteal estimation0.10.20.6-0.6-0.4-0.4-0.4-0.60.5-0.30.6-0.70.70.70.70.2-0.80.00.20.30.1-0.4-0.3-0.3
Bone: periosteal perimeter0.20.31.50.20.30.30.40.3-0.20.6-0.10.1-0.1-0.1-0.11.20.10.9-0.71.0-0.80.40.50.7
Bone: post-yield work0.10.10.40.40.40.40.50.5-0.60.5-0.60.4-0.4-0.4-0.4-0.00.4-0.10.0-0.30.2-0.1-0.1-0.4
Progressive ratio test 1 active lever presses0.81.02.11.11.01.00.91.1-0.71.1-0.80.8-0.8-0.8-0.81.2-0.01.4-1.11.3-1.10.71.40.7
Progressive ratio test 1 breakpoint0.91.12.31.21.11.11.01.1-0.81.2-0.90.9-0.9-0.9-0.91.30.11.4-1.21.4-1.10.81.50.8
Progressive ratio test 1 inactive lever presses0.20.31.5-0.6-0.4-0.4-0.6-0.50.7-0.20.7-0.70.60.60.60.3-1.20.20.00.5-0.10.10.30.4
Progressive ratio test 2 active lever presses4.24.97.22.32.52.52.12.2-1.92.4-2.22.0-2.1-2.1-2.12.60.82.7-2.42.5-2.32.02.51.7
Progressive ratio test 2 breakpoint4.45.07.32.32.52.52.22.2-2.02.4-2.22.0-2.1-2.1-2.12.60.82.7-2.42.5-2.32.02.41.7
Progressive ratio test 2 inactive lever presses1.42.34.21.51.71.71.31.4-1.01.7-1.41.2-1.3-1.3-1.31.9-0.12.1-1.72.0-1.71.42.01.3
Incentive Sensitization - Responses3.54.96.92.52.62.62.22.1-2.12.4-2.12.0-2.2-2.2-2.22.50.92.6-2.42.3-2.22.12.01.5
Incentive Sensitization - Breakpoint3.24.25.92.32.42.42.12.0-1.92.3-2.01.9-2.0-2.0-2.02.30.92.4-2.22.1-2.01.91.91.5
Sum of active levers in priming session hrs 5-62.42.24.11.71.71.71.91.9-2.02.0-1.91.5-1.7-1.7-1.71.21.01.3-1.10.6-0.70.31.1-0.2
Progressive ratio0.10.10.8-0.20.20.2-0.00.20.10.0-0.1-0.2-0.1-0.1-0.10.40.10.1-0.30.3-0.30.50.20.9
Food seeking constrained by brief footshock0.10.10.5-0.3-0.3-0.3-0.3-0.50.3-0.50.3-0.20.20.20.2-0.1-0.0-0.40.2-0.30.20.0-0.7-0.2
Seeking ratio, punishment vs. effort0.81.12.3-0.8-1.1-1.1-1.0-1.21.0-1.11.1-0.81.01.01.0-1.2-1.1-1.01.1-1.01.1-1.1-0.9-1.5
Retroperitoneal fat weight0.41.83.91.91.31.31.31.4-1.31.3-1.52.0-1.8-1.8-1.80.30.51.2-1.00.9-0.90.71.60.4
Reaction time number correct0.00.10.40.10.10.10.40.2-0.40.4-0.00.0-0.0-0.0-0.00.60.40.3-0.30.2-0.20.1-0.0-0.1
Reaction time mean minus median0.00.10.6-0.0-0.3-0.3-0.2-0.10.3-0.40.20.1-0.1-0.1-0.10.00.2-0.0-0.20.2-0.30.70.30.7
Reaction time mean minus median AUC0.51.22.91.00.70.70.91.0-0.80.7-0.71.0-1.0-1.0-1.01.31.51.0-1.21.0-1.31.71.11.5
Reaction time num false alarms0.81.13.30.80.70.70.60.7-0.40.6-0.80.8-0.7-0.7-0.71.10.61.4-1.31.6-1.51.61.31.8
Reaction time num false alarms AUC0.60.92.70.60.60.60.50.6-0.30.5-0.60.5-0.6-0.6-0.61.00.51.2-1.21.5-1.41.51.11.6
Reaction time trials correct on left0.00.10.40.10.10.10.40.2-0.40.4-0.00.0-0.0-0.0-0.00.60.40.3-0.30.2-0.20.1-0.0-0.1
Reaction time trials on left0.00.10.40.10.10.10.40.2-0.40.4-0.00.0-0.0-0.0-0.00.70.40.3-0.30.3-0.20.20.0-0.1
Reaction time mean0.10.10.70.1-0.2-0.2-0.5-0.30.5-0.60.5-0.10.00.00.0-0.8-0.2-0.40.3-0.40.30.0-0.0-0.0
Reaction time mean AUC0.10.20.6-0.1-0.4-0.4-0.6-0.50.7-0.80.6-0.30.20.20.2-0.7-0.2-0.40.3-0.30.10.10.00.2
Median of all reaction times0.10.21.10.0-0.3-0.3-0.6-0.40.5-0.70.5-0.30.20.20.2-1.0-0.4-0.50.5-0.60.5-0.3-0.1-0.3
Reaction time omissions0.00.00.10.00.10.1-0.00.00.0-0.1-0.10.1-0.1-0.1-0.1-0.00.2-0.10.0-0.1-0.00.10.1-0.0
Reaction time false alarm rate0.40.62.20.60.60.60.40.5-0.20.3-0.60.5-0.5-0.5-0.50.60.40.9-1.01.2-1.11.31.01.5
Reaction time premature initiation rate0.81.01.61.21.01.01.11.1-1.11.2-1.21.2-1.3-1.3-1.30.70.90.9-0.90.6-0.80.90.50.8
Reaction time premature initiations0.71.21.91.11.11.11.31.2-1.31.4-1.21.2-1.3-1.3-1.31.11.11.0-1.10.8-0.91.10.60.8
Std. dev. reaction times0.10.10.4-0.2-0.3-0.3-0.3-0.20.4-0.50.5-0.20.10.10.1-0.10.3-0.2-0.0-0.0-0.20.60.00.6
Reaction time trials completed0.00.10.40.10.10.10.40.2-0.40.4-0.00.0-0.0-0.0-0.00.70.40.3-0.30.3-0.20.20.0-0.1
Reaction time trials AUC0.00.10.60.00.10.10.40.2-0.30.4-0.0-0.0-0.0-0.0-0.00.80.50.4-0.30.3-0.30.20.0-0.0
Run reversals in cocaine runway, females0.20.21.60.2-0.1-0.10.20.2-0.10.1-0.00.2-0.2-0.2-0.20.50.30.4-0.50.5-0.61.00.41.2
Run reversals in cocaine runway, males1.51.53.91.01.01.00.91.2-0.71.0-1.11.2-1.1-1.1-1.11.20.81.5-1.41.7-1.51.32.01.4
Latency to leave start box in cocaine runway0.60.61.9-0.8-0.8-0.8-0.7-0.80.6-0.80.8-0.90.80.80.8-0.7-0.3-1.00.8-0.90.8-0.6-1.4-0.5
Latency to leave start box in cocaine runway, F1.41.65.4-1.2-1.2-1.2-1.0-1.20.7-1.21.1-1.21.11.11.1-1.3-0.3-1.71.4-1.81.5-1.0-2.3-1.1
Latency to leave start box in cocaine runway, M0.20.20.70.40.40.40.30.4-0.10.4-0.30.3-0.3-0.3-0.30.40.00.6-0.50.7-0.50.30.80.3
Std. dev. time between licks in bursts0.30.40.60.60.70.70.60.7-0.60.5-0.80.7-0.8-0.8-0.80.30.60.5-0.60.4-0.50.60.70.5
Total sessions with >9 infusions1.31.53.91.11.21.21.21.3-1.01.5-1.01.0-0.7-0.7-0.72.00.31.7-1.51.7-1.41.11.40.8
Short access day 1 total inactive lever presses0.10.20.60.10.40.40.50.4-0.40.7-0.60.3-0.3-0.3-0.30.80.20.5-0.50.6-0.40.20.00.1
Short access day 10 total inactive lever presses0.20.51.3-1.2-0.7-0.7-0.9-1.11.0-0.70.7-1.00.80.80.8-0.4-0.8-0.30.40.00.2-0.5-1.0-0.2
Short access day 1 total infusions0.40.51.90.40.60.60.40.3-0.10.6-0.20.10.10.10.11.3-0.11.1-0.91.4-1.00.70.90.8
Short access day 10 total infusions1.41.84.61.31.11.11.11.1-0.81.3-0.81.1-0.9-0.9-0.92.00.22.0-1.62.1-1.71.21.91.1
Short access total infusions0.40.51.80.50.50.50.40.5-0.20.6-0.30.4-0.2-0.2-0.21.2-0.21.1-0.91.3-1.00.71.10.7
Short access day 1 locomotion0.30.31.1-0.20.00.0-0.1-0.10.40.20.3-0.50.70.70.71.0-1.00.8-0.41.1-0.60.10.70.0
Short access day 10 total locomotion0.10.20.8-0.20.10.1-0.2-0.30.40.10.3-0.50.40.40.40.5-0.70.6-0.40.9-0.50.20.10.2
Short access total locomotion0.30.41.6-0.3-0.1-0.1-0.2-0.30.50.20.4-0.60.70.70.71.1-1.00.8-0.51.3-0.70.40.50.3
One hour access (0.3 mA shock)3.03.44.21.92.02.01.82.0-1.71.9-1.81.9-1.9-1.9-1.91.81.32.0-1.91.9-1.81.62.01.6
Compulsive drug intake0.30.41.6-0.10.10.10.0-0.1-0.3-0.1-0.30.1-0.4-0.4-0.4-1.10.3-1.00.7-1.31.0-0.7-1.1-0.9
One hour access (shock baseline)0.81.33.21.01.01.00.91.1-0.71.1-0.60.8-0.6-0.6-0.61.50.41.6-1.31.7-1.41.11.80.9
Social response proportion0.50.62.20.10.40.40.50.5-0.90.4-0.50.2-0.4-0.4-0.4-0.70.7-0.90.6-1.51.1-0.9-1.1-1.4
Social responses0.50.71.70.80.90.91.01.0-1.30.9-1.10.9-0.9-0.9-0.90.11.30.1-0.3-0.40.10.1-0.0-0.4
Social time0.40.53.00.60.50.50.91.0-1.10.6-0.90.9-0.8-0.8-0.8-0.01.7-0.4-0.1-0.60.20.2-0.2-0.1
Soleus weight1.64.69.72.42.62.62.72.8-3.12.8-2.62.3-2.5-2.5-2.51.52.41.1-1.30.0-0.50.61.1-0.1
Bone: stiffness0.20.30.60.20.60.60.50.5-0.70.6-0.70.3-0.5-0.5-0.5-0.30.4-0.30.2-0.60.5-0.6-0.5-0.8
Tibialis anterior weight8.227.636.05.56.06.05.85.8-5.85.7-5.95.5-5.6-5.6-5.64.96.04.6-5.03.5-4.34.54.03.7
Time to tail flick, vehicle, before self-admin4.85.07.82.42.52.52.62.4-2.82.5-2.42.4-2.5-2.5-2.52.02.81.7-2.01.2-1.61.91.31.3
Time to tail flick, vehicle, after self-admin0.10.20.80.40.20.20.40.4-0.50.3-0.30.4-0.5-0.5-0.50.20.90.0-0.2-0.1-0.10.4-0.00.7
Time to tail flick, test, before self-admin0.70.72.3-0.8-0.5-0.5-0.4-0.40.1-0.70.4-0.70.60.60.6-0.81.0-1.50.9-1.51.1-0.3-1.5-0.3
Time to tail flick, test, after self-admin0.50.61.9-0.8-0.6-0.6-0.7-0.60.6-0.80.6-0.50.50.50.5-1.4-0.5-1.00.9-1.00.9-0.7-0.5-0.7
Delta time to tail flick, vehicle, before/after SA1.21.22.1-1.3-1.4-1.4-1.3-1.21.4-1.41.3-1.21.31.31.3-0.8-0.6-0.80.7-0.30.5-0.4-0.70.2
Delta time to tail flick, test, before/after SA0.60.61.90.60.60.60.40.4-0.20.6-0.60.8-0.7-0.7-0.70.4-0.61.3-0.91.3-1.00.61.40.5
Tibia length1.23.48.1-1.5-1.2-1.2-1.5-1.41.1-1.61.0-1.41.11.11.1-2.4-1.3-2.52.3-2.82.5-2.6-2.3-2.3
Ambulatory time before self-admin2.43.68.7-1.9-2.0-2.0-2.3-1.92.4-2.12.1-2.01.81.81.8-1.9-3.0-1.51.8-1.11.5-1.7-0.4-1.3
Ambulatory time after self-admin0.70.82.2-0.6-0.7-0.7-0.8-0.70.6-0.60.8-0.90.80.80.8-1.1-1.1-0.91.0-0.91.1-1.2-0.6-1.5
Bone: tissue strength2.82.94.7-2.2-1.9-1.9-1.8-1.81.8-1.71.5-1.81.81.81.8-1.6-1.8-1.71.6-1.31.5-1.5-1.5-1.1
Total heroin consumption4.04.78.12.42.72.72.62.5-2.82.6-2.82.5-2.7-2.7-2.71.32.11.4-1.50.5-0.91.00.50.5
Bone: trabecular number4.37.010.43.03.03.03.03.0-3.12.8-3.23.2-3.0-3.0-3.02.03.02.0-2.31.4-1.81.91.81.5
Bone: trabecular spacing0.20.30.7-0.7-0.5-0.5-0.6-0.60.7-0.50.6-0.80.60.60.6-0.1-0.80.10.20.3-0.0-0.3-0.20.0
Bone: trabecular thickness0.20.20.50.50.70.70.50.6-0.60.4-0.60.5-0.5-0.5-0.50.10.70.0-0.2-0.2-0.10.40.10.2
Bone: trabecular tissue density1.82.64.2-1.6-1.7-1.7-1.9-2.02.0-2.01.8-1.61.71.71.7-1.7-2.1-1.31.5-1.11.2-1.1-1.1-1.0
Water consumed over 24 hours1.52.03.1-1.4-1.3-1.3-1.2-1.21.0-1.21.2-1.31.41.41.4-1.7-1.2-1.71.6-1.81.7-1.6-1.5-1.7
Number of responses in last shaping day0.30.31.7-0.5-0.1-0.1-0.3-0.30.7-0.1-0.0-0.20.40.40.40.5-0.80.8-0.51.3-0.80.20.80.4