Hub : Genes

Rap1gap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Rap1gap2 0.24 0.12 2.5e-11 0.19 0.18 0.18 0.17 1.8e-10 4.8e-10 9.5e-10 1.4e-09
2 NAcc gene expression Rap1gap2 0.06 0.04 2.6e-07 0.05 0.05 0.04 0.04 3.2e-06 1.3e-06 5.0e-06 6.7e-06
3 BLA alternative TSS NM_001401654.1 0.08 0.06 2.0e-03 0.04 0.03 0.01 0.02 4.8e-03 1.5e-02 5.0e-02 2.4e-02
4 Brain mRNA stability Rap1gap2 0.15 0.07 1.2e-15 0.16 0.17 0.18 0.18 6.8e-15 7.0e-16 1.1e-16 7.8e-17
5 OFC gene expression Rap1gap2 0.63 0.15 8.3e-13 0.47 0.48 0.49 0.5 1.0e-12 3.4e-13 2.9e-13 1.4e-13
6 Brain alternative TSS XM_008767832.3 0.03 0.03 7.8e-03 0.03 0.02 0.02 0.03 1.3e-03 4.2e-03 4.0e-03 1.4e-03
7 Brain isoform ratio XM_008767832.3 0.03 0.03 8.7e-03 0.03 0.02 0.02 0.02 1.9e-03 8.5e-03 4.5e-03 2.5e-03
8 PL mRNA stability Rap1gap2 0.09 0.05 2.3e-11 0.11 0.11 0.1 0.11 8.2e-12 8.8e-12 1.5e-11 7.0e-12
9 PL isoform ratio NM_001401654.1 0.04 0.03 3.5e-05 0.05 0.05 0.04 0.04 2.2e-06 4.9e-06 1.6e-05 1.1e-05
10 PL alternative TSS NM_001401654.1 0.04 0.03 3.4e-04 0.04 0.04 0.03 0.03 6.4e-05 8.3e-05 2.1e-04 1.5e-04
11 Brain gene expression Rap1gap2 0.39 0.08 0.0e+00 0.52 0.53 0.53 0.53 7.4e-56 5.8e-58 3.7e-58 3.0e-58
12 PL gene expression Rap1gap2 0.4 0.15 0.0e+00 0.4 0.38 0.4 0.4 4.7e-47 8.0e-45 1.8e-46 3.6e-46
13 PL intron excision ratio chr10_59356749_59394399 0.08 0.05 7.8e-09 0.08 0.08 0.08 0.09 5.6e-09 4.5e-09 8.6e-09 7.0e-10
14 IL gene expression Rap1gap2 0.89 0.05 1.9e-13 0.35 0.28 0.39 0.18 2.2e-09 2.0e-07 1.8e-10 4.4e-05
15 PL isoform ratio XM_008767832.3 0.03 0.02 6.9e-03 0 0.01 0.01 0 2.5e-01 1.8e-02 5.6e-02 9.3e-02
16 PL alternative TSS XM_017597290.2 0.08 0.06 1.8e-06 0.03 0.05 0.05 0.05 1.0e-04 3.3e-06 3.8e-06 7.2e-06
17 PL alternative TSS XM_008767832.3 0.04 0.03 3.4e-04 0 0.02 0.01 0.01 7.9e-02 3.2e-03 1.1e-02 1.7e-02
18 Brain alternative TSS XM_017597290.2 0.05 0.04 9.6e-05 0.02 0.04 0.03 0.03 6.1e-03 1.9e-04 1.2e-03 2.0e-03
19 Brain isoform ratio XM_017597290.2 0.06 0.04 1.0e-05 0.05 0.06 0.05 0.05 2.3e-05 6.9e-06 9.5e-06 1.6e-05
20 PL alternative TSS XM_039086003.1 0.05 0.04 4.3e-05 0.03 0.04 0.03 0.02 2.3e-04 7.3e-05 6.8e-04 2.0e-03
21 PL isoform ratio XM_017597290.2 0.06 0.04 5.1e-06 0.04 0.05 0.05 0.05 4.3e-05 5.6e-06 6.3e-06 6.7e-06
22 PL intron excision ratio chr10_59356749_59432200 0.02 0.02 3.0e-03 0.02 0.01 0.02 0.01 3.7e-03 1.5e-02 3.0e-03 1.0e-02
23 PL isoform ratio XM_039086003.1 0.05 0.04 4.1e-04 0.01 0.03 0.02 0.01 2.0e-02 7.1e-04 1.7e-03 9.7e-03
24 Liver gene expression Rap1gap2 0.14 0.09 2.3e-13 0.1 0.1 0.1 0.1 1.6e-11 9.7e-12 6.6e-11 9.9e-12
25 Brain intron excision ratio chr10_59356749_59394399 0.04 0.04 9.1e-04 0.03 0.02 0.03 0.02 8.3e-04 2.7e-03 1.2e-03 3.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density3.86.48.2-2.72.82.92.52.32.82.82.72.82.82.8-2.82.5-2.8-2.82.0-2.82.12.02.81.82.22.71.8-1.6
Area under the delay curve0.70.82.00.7-1.0-0.9-1.2-0.6-1.2-1.2-0.7-1.0-1.0-1.00.6-0.91.40.8-0.50.8-0.8-0.7-0.7-0.6-0.7-0.6-0.80.6
BMI with tail1.65.26.5-2.42.32.52.22.62.42.42.32.42.42.4-2.42.2-2.1-2.32.4-2.22.32.32.12.22.32.02.0-1.9
BMI without tail0.30.61.6-1.00.90.90.40.90.50.50.80.70.70.8-1.10.5-0.4-1.10.6-1.10.50.51.20.50.51.20.2-0.3
Body weight0.83.29.3-1.92.12.10.81.51.91.91.82.12.11.8-2.01.1-1.7-2.60.8-2.70.70.62.90.40.63.10.10.4
Weight adjusted by age2.32.63.8-1.71.61.91.51.81.31.31.82.02.01.6-1.81.8-1.1-1.71.8-1.61.51.51.71.61.61.61.3-1.3
Bone surface4.27.39.1-2.92.83.02.72.82.92.92.82.92.92.9-3.02.6-2.9-2.82.4-2.72.52.42.62.32.52.52.2-2.1
Bone volume4.57.79.6-3.03.03.12.82.92.92.92.92.92.93.0-3.02.7-3.0-2.92.6-2.82.62.62.72.42.62.62.3-2.2
Breakpoint value in progressive ratio session0.70.72.3-1.00.91.10.20.71.11.10.81.01.00.8-1.00.5-0.5-1.30.4-1.30.20.21.40.20.31.5-0.10.1
Number of licking bursts0.20.30.50.7-0.6-0.6-0.5-0.7-0.6-0.6-0.4-0.6-0.6-0.60.6-0.30.60.7-0.30.7-0.4-0.3-0.7-0.3-0.4-0.7-0.20.2
Context. condit. distance diff. score1.21.42.3-1.21.41.40.90.91.21.21.41.31.31.3-1.41.2-1.3-1.50.9-1.50.90.81.50.70.81.50.7-0.5
Locomotion velocity, session 11.51.64.4-1.51.61.30.91.01.11.11.31.31.31.4-1.50.8-1.5-1.90.5-1.90.50.52.00.30.42.10.20.1
Locomotion distance, session 10.60.81.2-0.81.01.11.10.80.90.90.81.11.11.0-0.80.9-1.0-0.90.6-0.90.70.70.90.60.80.80.7-0.6
Locomotion velocity, session 20.50.61.1-0.91.00.90.80.70.80.80.80.90.90.9-0.80.7-1.0-1.00.4-1.00.50.51.00.40.51.00.4-0.2
Locomotion distance, session 21.82.53.1-1.71.71.71.61.51.71.71.61.71.71.8-1.71.5-1.7-1.71.3-1.71.41.31.61.21.41.61.2-1.1
Locomotion velocity, session 36.27.39.12.8-2.9-2.8-2.5-2.8-3.0-3.0-3.0-2.9-2.9-2.82.9-2.92.82.8-2.62.7-2.5-2.5-2.6-2.4-2.4-2.5-2.32.0
Locomotion distance, session 30.00.00.1-0.10.00.10.40.30.20.2-0.10.10.10.2-0.0-0.1-0.20.00.20.10.30.3-0.10.30.3-0.20.3-0.4
Stereotopy head waving bouts, day 30.40.51.20.7-0.5-0.2-0.6-0.9-0.4-0.4-0.7-0.3-0.3-0.50.7-0.50.40.4-1.10.3-0.9-1.0-0.3-1.1-0.7-0.2-0.91.1
Stereotopy head waving duration, day 30.30.40.90.9-0.7-0.3-0.3-0.9-0.5-0.5-0.6-0.4-0.4-0.60.8-0.30.40.9-0.70.8-0.5-0.5-0.9-0.5-0.3-0.9-0.30.3
Locomotion velocity, session 72.02.23.4-1.81.51.51.41.81.31.31.51.51.51.5-1.61.4-1.2-1.41.7-1.41.61.61.31.61.51.21.4-1.4
Locomotion distance, session 73.84.86.4-2.52.22.31.92.52.22.22.32.32.32.2-2.42.1-1.8-2.22.5-2.12.22.22.02.32.12.02.0-1.8
Stereotopy head waving bouts, day 70.50.51.4-0.60.81.20.90.40.90.90.61.01.00.8-0.60.8-1.0-0.80.1-0.80.30.20.80.10.60.80.2-0.2
Stereotopy head waving duration, day 70.70.91.9-0.91.01.41.10.71.11.10.81.21.21.1-0.80.9-1.3-1.00.3-1.10.50.41.00.30.81.00.4-0.4
Locomotion velocity, session 80.30.40.8-0.60.80.70.90.50.50.50.60.60.60.7-0.60.7-0.9-0.70.4-0.70.60.50.60.50.60.60.6-0.6
Locomotion distance, session 82.02.94.9-1.82.02.11.41.31.91.91.82.02.01.9-1.91.7-1.8-2.11.1-2.21.11.02.20.91.22.20.8-0.6
Degree of sensitization distance1.71.72.7-1.61.41.40.71.31.31.31.61.41.41.3-1.51.3-1.0-1.61.3-1.61.11.11.61.10.91.70.8-0.6
Degree of sensitization stereotypy0.70.71.4-0.91.01.20.80.60.90.90.81.11.11.0-0.80.8-1.1-1.10.1-1.10.30.21.20.10.51.20.2-0.1
Conditioned locomotion0.70.91.91.2-1.1-1.0-0.4-1.0-0.7-0.7-1.1-0.9-0.9-0.91.2-0.70.61.3-0.91.2-0.7-0.7-1.3-0.7-0.5-1.4-0.40.3
Cocaine response after cond. corrected0.10.10.30.2-0.00.2-0.2-0.40.10.1-0.10.20.2-0.10.20.10.1-0.1-0.4-0.2-0.4-0.50.3-0.5-0.20.3-0.50.4
Cocaine response after cond. not corrected0.10.10.5-0.30.30.50.0-0.00.40.40.20.60.60.3-0.10.3-0.2-0.5-0.2-0.6-0.2-0.20.7-0.30.00.7-0.30.4
Cocaine response before conditioning1.01.21.8-1.31.21.11.01.31.11.11.11.11.11.1-1.20.8-1.2-1.30.9-1.30.90.91.30.80.81.30.7-0.4
Saline control response1.21.61.9-1.31.31.31.41.31.11.11.31.21.21.3-1.31.3-1.1-1.21.4-1.11.31.31.01.31.31.01.3-1.3
Bone: connectivity density6.19.612.5-3.23.33.43.23.03.53.53.23.53.53.4-3.33.1-3.4-3.32.5-3.32.62.53.22.32.93.02.2-2.2
Bone: cortical apparent density0.10.10.50.3-0.2-0.20.2-0.1-0.3-0.3-0.0-0.2-0.2-0.20.30.30.20.50.30.50.20.3-0.60.30.3-0.70.4-0.6
Bone: cortical area1.01.42.91.2-1.4-1.3-1.3-0.9-1.5-1.5-1.1-1.4-1.4-1.31.1-1.11.71.5-0.51.5-0.8-0.7-1.5-0.5-0.8-1.4-0.60.2
Bone: cortical porosity0.20.20.5-0.50.50.50.20.40.40.40.60.40.40.5-0.70.4-0.3-0.60.4-0.60.30.30.60.30.30.60.2-0.1
Bone: cortical porosity0.00.00.1-0.10.10.2-0.20.1-0.0-0.00.20.10.10.1-0.30.00.1-0.20.1-0.20.00.00.20.0-0.00.3-0.00.0
Bone: cortical thickness5.69.111.63.2-3.3-3.2-3.1-3.0-3.3-3.3-3.2-3.2-3.2-3.33.1-3.03.43.2-2.63.2-2.8-2.7-3.1-2.5-2.6-2.9-2.51.9
Bone: cortical thickness1.92.22.91.7-1.5-1.4-1.7-1.7-1.3-1.3-1.5-1.4-1.4-1.51.5-1.61.51.3-1.61.3-1.6-1.6-1.2-1.6-1.5-1.0-1.61.5
Bone: cortical tissue density0.10.10.30.2-0.1-0.10.3-0.1-0.2-0.20.1-0.1-0.1-0.10.20.40.10.30.30.40.30.3-0.50.40.3-0.50.5-0.6
Condit. Reinf. active minus inactive responses0.50.50.90.7-0.7-0.7-0.8-0.8-0.8-0.8-0.7-0.6-0.6-0.60.5-0.90.70.5-0.80.5-0.8-0.8-0.4-0.8-0.9-0.4-0.80.9
Condit. Reinf. active-inactive response ratio3.94.26.22.0-2.0-2.0-2.4-2.1-2.2-2.2-2.1-2.0-2.0-2.01.8-2.52.11.6-2.21.6-2.3-2.3-1.4-2.2-2.3-1.2-2.32.2
Condit. Reinf. active responses0.30.40.6-0.50.60.70.60.50.60.60.70.80.80.7-0.80.6-0.6-0.60.5-0.60.50.50.50.50.60.50.5-0.4
Condit. Reinf. inactive responses5.86.910.1-2.42.52.73.02.52.62.62.82.72.72.7-2.53.2-2.5-2.12.9-2.02.92.91.72.93.01.52.9-2.8
Incentive salience index mean0.50.61.20.8-0.6-0.6-0.8-0.9-0.8-0.8-0.8-0.6-0.6-0.60.5-1.10.50.4-1.00.4-0.9-1.0-0.3-1.0-1.0-0.2-1.01.1
Condit. Reinf. lever presses0.20.31.20.10.10.1-0.4-0.40.00.0-0.20.20.20.1-0.1-0.6-0.2-0.4-0.8-0.5-0.7-0.80.6-0.9-0.70.7-0.91.1
Condit. Reinf. active minus inactive responses1.31.72.3-1.31.31.51.11.31.21.21.51.41.41.3-1.41.4-0.9-1.31.4-1.21.31.31.21.31.31.21.1-1.1
Condit. Reinf. active-inactive response ratio0.00.00.1-0.10.00.2-0.3-0.0-0.0-0.00.10.20.2-0.0-0.10.10.3-0.20.1-0.2-0.1-0.10.2-0.1-0.00.3-0.20.2
Condit. Reinf. active responses3.14.35.8-2.12.02.22.02.31.91.92.22.12.12.0-2.22.2-1.6-1.82.4-1.82.22.31.62.32.31.52.1-2.1
Condit. Reinf. inactive responses5.16.38.9-2.52.32.42.92.92.32.32.52.32.32.5-2.52.6-2.2-1.93.0-1.82.92.91.63.02.91.32.9-3.0
Condit. Reinf. lever presses0.30.41.3-0.30.20.30.80.60.40.40.40.30.30.3-0.30.6-0.30.10.90.20.90.9-0.41.00.9-0.51.1-1.2
Condit. Reinf. lever reinforcers received3.14.46.3-2.22.02.22.02.41.91.92.22.12.12.0-2.22.2-1.6-1.82.5-1.72.32.31.62.42.31.42.2-2.2
Conditioned reinforcement - actives3.63.64.7-2.02.01.82.12.11.91.92.01.71.71.9-1.91.9-1.8-1.82.2-1.82.12.11.62.11.81.51.9-1.9
Conditioned reinforcement - inactives1.92.13.1-1.71.51.31.31.71.21.21.61.41.41.4-1.61.6-1.0-1.41.8-1.31.61.61.31.61.41.21.4-1.5
Conditioned locomotion0.10.10.30.0-0.3-0.40.10.2-0.2-0.2-0.20.10.1-0.10.1-0.10.10.40.20.50.20.2-0.50.20.2-0.60.2-0.4
Patch foraging indifference point 0 sec0.10.20.3-0.50.50.50.40.60.40.40.20.30.30.4-0.40.1-0.6-0.50.2-0.50.30.30.40.20.40.40.3-0.2
Patch foraging indifference point AUC0.30.31.30.10.10.10.50.20.10.10.50.20.20.2-0.20.70.00.20.90.20.80.8-0.30.90.8-0.50.9-1.1
Delay disc. indifference point, 0s delay0.20.20.4-0.60.50.20.50.60.40.40.40.10.10.4-0.50.2-0.3-0.50.5-0.50.40.40.50.50.30.50.4-0.2
Delay disc. indifference point, 16s delay0.10.10.8-0.1-0.20.0-0.50.2-0.5-0.50.20.00.0-0.2-0.10.30.90.20.60.20.10.3-0.20.40.3-0.10.1-0.6
Delay disc. indifference point, 2s delay0.70.81.60.9-1.0-1.0-1.0-0.9-1.2-1.2-0.8-1.0-1.0-1.00.9-0.81.20.9-0.70.9-0.8-0.8-0.9-0.7-0.8-0.8-0.70.7
Delay disc. indifference point, 24s delay0.00.00.3-0.1-0.10.0-0.30.2-0.1-0.10.20.10.1-0.0-0.20.10.6-0.00.30.00.10.10.00.20.20.1-0.0-0.2
Delay disc. indifference point, 4s delay0.30.31.10.4-0.5-0.5-0.9-0.5-0.7-0.7-0.4-0.4-0.4-0.60.3-0.51.10.3-0.40.3-0.6-0.6-0.2-0.5-0.6-0.1-0.70.5
Delay disc. indifference point, 8s delay0.40.41.20.4-0.6-0.6-0.9-0.5-0.8-0.8-0.5-0.8-0.8-0.70.4-0.71.10.5-0.40.5-0.6-0.6-0.4-0.5-0.7-0.3-0.60.6
Indifference point function ln k0.40.51.1-0.90.80.90.70.70.90.90.60.70.70.8-0.70.3-0.9-1.00.1-1.00.30.21.00.10.31.00.10.0
Indifference point function log k0.40.51.1-0.90.80.90.70.70.90.90.60.70.70.8-0.70.3-0.9-1.00.1-1.00.30.21.00.10.31.00.10.0
Patch foraging total patch changes 0 sec0.10.20.4-0.40.50.50.50.60.40.40.20.30.30.4-0.40.2-0.6-0.40.3-0.40.40.40.40.30.40.40.4-0.3
Patch foraging total patch changes 12 sec0.81.11.41.1-1.1-1.2-1.0-1.0-1.1-1.1-1.2-1.0-1.0-1.11.0-1.11.01.0-1.01.0-1.0-1.0-1.0-1.0-0.9-0.9-0.90.8
Patch foraging total patch changes 18 sec0.40.50.91.0-0.8-0.8-0.9-0.8-0.8-0.8-0.7-0.6-0.6-0.90.8-0.50.90.8-0.50.8-0.6-0.6-0.7-0.5-0.5-0.7-0.60.4
Patch foraging total patch changes 24 sec0.50.61.01.0-0.9-0.7-0.7-0.7-0.8-0.8-0.9-0.7-0.7-0.90.8-0.60.91.0-0.41.0-0.5-0.5-1.0-0.4-0.3-1.0-0.40.2
Patch foraging total patch changes 6 sec0.10.10.40.2-0.2-0.20.20.1-0.2-0.2-0.1-0.3-0.3-0.10.10.00.00.40.30.40.30.3-0.60.40.4-0.60.5-0.6
Patch foraging time to switch 0 sec2.13.24.91.8-1.8-1.8-2.1-2.0-1.6-1.6-1.9-1.4-1.4-1.82.0-1.81.61.5-2.11.4-2.1-2.1-1.3-2.1-1.9-1.1-2.12.2
Patch foraging water rate 0 sec0.50.81.8-0.80.80.81.21.00.60.60.80.40.40.9-0.90.8-0.9-0.51.1-0.51.21.20.41.20.90.21.2-1.3
Patch foraging water rate 12 sec0.10.20.5-0.60.50.60.10.50.20.20.60.10.10.4-0.70.3-0.2-0.60.5-0.60.40.40.70.40.00.70.3-0.2
Patch foraging water rate 18 sec3.44.56.1-2.42.42.32.12.32.02.02.41.91.92.3-2.51.9-2.2-2.42.0-2.42.02.02.31.91.72.21.8-1.5
Patch foraging water rate 24 sec0.20.30.7-0.50.60.50.80.60.40.40.50.20.20.6-0.60.3-0.7-0.40.7-0.40.80.70.30.70.40.20.8-0.6
Patch foraging water rate 6 sec0.00.10.20.1-0.1-0.10.00.0-0.4-0.4-0.1-0.3-0.3-0.10.1-0.10.20.30.20.30.20.2-0.40.3-0.0-0.40.3-0.2
Seeking ratio, delayed vs. immediate footshock0.50.61.90.9-1.0-0.7-0.5-0.6-0.5-0.5-0.6-0.9-0.9-0.70.6-0.50.91.2-0.21.2-0.2-0.2-1.3-0.1-0.2-1.40.0-0.3
Distance traveled before self-admin1.11.22.41.1-1.3-1.2-1.0-0.9-1.1-1.1-1.2-1.2-1.2-1.21.2-0.91.61.4-0.71.4-0.8-0.8-1.4-0.6-0.7-1.4-0.60.4
Distance traveled after self-admin0.00.00.2-0.1-0.1-0.0-0.20.1-0.1-0.1-0.1-0.2-0.2-0.1-0.0-0.30.40.0-0.10.0-0.2-0.20.0-0.2-0.20.1-0.30.1
Extensor digitorum longus weight5.822.928.3-4.85.05.25.34.95.15.14.95.15.15.2-5.04.9-5.3-4.64.4-4.64.74.64.34.34.73.94.4-3.8
Bone: elastic displacement0.20.30.90.7-0.6-0.6-0.0-0.5-0.6-0.6-0.4-0.5-0.5-0.50.5-0.10.50.8-0.10.8-0.1-0.0-0.90.00.0-1.00.1-0.4
Bone: elastic work5.77.49.13.0-3.0-2.9-2.5-2.7-3.0-3.0-3.0-3.0-3.0-2.82.8-2.92.82.9-2.52.9-2.5-2.4-2.8-2.3-2.4-2.7-2.21.7
Bone: endosteal estimation0.30.71.2-0.90.80.80.81.00.60.60.90.70.70.8-0.90.8-0.6-0.71.1-0.61.01.00.51.10.90.51.0-1.0
Bone: endosteal perimeter2.14.46.8-2.22.02.12.12.51.81.82.21.91.92.0-2.22.2-1.7-1.72.6-1.62.52.51.52.52.31.32.4-2.4
Epididymis fat weight4.19.515.5-3.43.53.42.32.93.53.53.43.43.43.3-3.52.9-2.8-3.82.5-3.82.32.23.92.12.23.91.7-1.4
Delta time in closed arm before/after self-admin0.00.00.10.0-0.0-0.10.20.1-0.1-0.10.20.10.1-0.0-0.10.30.20.20.20.20.20.2-0.30.30.4-0.30.3-0.4
Delta time in open arm before/after self-admin0.60.61.4-0.80.81.20.40.80.90.90.61.01.00.8-0.70.6-0.8-0.90.6-0.90.50.51.00.50.61.00.3-0.3
Diff in mean of infusions in LGA sessions0.20.20.7-0.20.30.2-0.2-0.20.20.20.00.20.20.1-0.2-0.2-0.1-0.6-0.4-0.6-0.4-0.50.7-0.5-0.40.8-0.70.8
Delay discount exponential model param0.80.92.2-0.71.00.91.30.71.21.20.81.01.01.0-0.71.0-1.5-0.80.7-0.80.90.90.70.70.90.60.9-0.7
Extinction: sum of active levers before priming3.83.85.3-2.22.22.31.51.92.02.02.12.22.22.0-2.21.9-1.7-2.31.8-2.31.61.62.31.51.52.31.3-1.0
Active lever presses in extinction session 62.01.93.0-1.41.51.51.31.41.61.61.31.71.71.4-1.41.2-1.3-1.51.2-1.51.11.11.51.01.31.50.9-0.8
Bone: final force1.32.14.21.2-1.4-1.2-1.8-1.2-1.5-1.5-1.6-1.4-1.4-1.31.1-2.11.31.1-1.61.1-1.6-1.7-0.9-1.6-1.6-0.7-1.71.6
Bone: final moment1.11.83.61.1-1.3-1.2-1.6-1.0-1.5-1.5-1.5-1.3-1.3-1.21.0-1.91.21.0-1.51.0-1.5-1.5-0.9-1.5-1.5-0.7-1.51.4
Food consumed during 24 hour testing period0.30.40.7-0.80.70.70.50.80.80.80.60.60.60.7-0.70.4-0.7-0.70.5-0.70.50.50.70.40.40.70.4-0.3
Glucose2.13.25.22.0-2.1-2.0-1.7-1.6-2.1-2.1-1.8-2.1-2.1-2.12.0-1.52.32.2-1.02.2-1.2-1.1-2.2-0.9-1.2-2.2-0.90.5
Heart weight0.10.20.5-0.40.40.7-0.00.50.40.40.40.50.50.4-0.60.2-0.1-0.60.2-0.50.10.10.70.00.20.7-0.10.1
Delay discount hyperbolic model param0.70.82.0-0.70.90.91.20.71.21.20.70.90.91.0-0.60.9-1.4-0.80.6-0.80.80.80.70.70.80.60.8-0.7
Intermittent access intake day 1-15 change1.01.02.9-0.60.50.41.41.00.80.80.50.50.50.6-0.30.9-0.6-0.01.40.01.41.5-0.31.61.4-0.51.6-1.7
Intermittent access intake escalation0.50.51.9-0.0-0.1-0.10.80.50.30.30.10.10.10.10.20.60.10.51.10.61.01.1-0.81.21.1-1.01.2-1.4
Intermittent access intake escalation 20.70.73.00.9-0.9-1.00.2-0.4-0.4-0.4-0.7-0.8-0.8-0.71.1-0.20.61.30.11.40.20.3-1.60.40.2-1.70.6-0.6
Intermitt. access day 1 inactive lever presses1.11.23.00.8-1.2-1.0-1.0-0.6-1.4-1.4-0.9-1.7-1.7-1.20.8-1.31.71.2-0.21.3-0.6-0.5-1.2-0.3-0.8-1.2-0.40.0
Intermitt. access day 15 inactive lever presses0.10.20.5-0.50.10.50.10.4-0.4-0.40.60.00.00.0-0.40.50.6-0.10.7-0.00.30.40.00.60.30.10.4-0.6
Intermitt. access escalation Index1.21.14.60.6-0.4-0.7-1.0-1.1-0.1-0.1-0.7-0.4-0.4-0.50.6-1.00.1-0.1-1.6-0.2-1.5-1.60.5-1.7-1.50.7-1.82.2
Intermittent access day 1 total infusions1.51.72.5-1.61.41.31.11.51.21.21.41.41.41.3-1.41.4-1.0-1.41.4-1.41.31.31.31.31.21.31.1-1.1
Intermittent access day 15 total infusions2.73.05.3-1.61.41.41.92.01.71.71.61.61.61.6-1.41.9-1.3-1.02.3-0.92.22.20.72.32.20.52.2-2.3
Intermittent access terminal intake (last 3 days)2.73.03.9-1.81.71.51.91.92.02.01.71.61.61.7-1.51.8-1.7-1.51.9-1.51.91.91.31.91.71.21.8-1.7
Intermittent access total infusions1.92.13.3-1.61.31.21.51.71.41.41.41.41.41.3-1.31.5-1.0-1.11.8-1.11.71.70.91.81.60.81.6-1.7
Intermittent access day 1 locomotion0.10.10.4-0.4-0.1-0.2-0.60.3-0.6-0.6-0.1-0.3-0.3-0.2-0.2-0.40.7-0.10.1-0.0-0.1-0.10.1-0.0-0.40.2-0.30.1
Intermittent access day 15 total locomotion0.20.21.0-0.40.0-0.20.40.60.00.00.3-0.1-0.10.1-0.20.40.20.20.90.20.70.8-0.30.90.6-0.40.8-1.0
Intermittent access total locomotion0.10.10.4-0.60.20.10.20.70.00.00.30.20.20.2-0.40.20.1-0.20.6-0.20.40.50.20.60.30.20.4-0.5
Intermittent access standard deviation1.92.06.6-1.10.70.81.61.60.90.91.00.90.90.9-0.71.6-0.5-0.12.2-0.02.02.1-0.32.32.0-0.52.3-2.6
Left kidney weight3.59.914.63.1-3.3-2.7-3.8-3.1-3.4-3.4-3.2-3.2-3.2-3.22.9-3.43.62.8-3.12.8-3.4-3.3-2.4-3.2-3.3-2.2-3.33.1
Right kidney weight2.98.213.12.8-2.9-2.5-3.6-2.9-3.1-3.1-2.8-2.8-2.8-2.92.6-3.13.32.4-2.92.4-3.2-3.1-2.0-3.0-3.1-1.7-3.23.0
Cocaine induced anxiety0.30.41.3-0.30.30.20.70.60.40.40.50.30.30.4-0.30.6-0.4-0.00.90.00.90.9-0.21.00.8-0.31.1-1.1
Post-drug Anxiety0.20.20.4-0.40.50.30.50.40.30.30.50.40.40.4-0.40.5-0.6-0.30.5-0.30.60.60.20.50.40.20.6-0.5
Baseline Anxiety0.10.10.20.1-0.10.0-0.3-0.2-0.3-0.3-0.10.10.1-0.20.1-0.10.2-0.1-0.3-0.1-0.3-0.40.2-0.4-0.30.2-0.40.5
Tail length1.23.611.90.9-0.7-0.9-2.5-1.7-1.2-1.2-1.2-1.1-1.1-1.10.7-2.11.0-0.3-2.7-0.4-2.7-2.80.9-3.0-2.81.3-3.23.5
Length with tail0.51.77.70.3-0.1-0.3-1.5-1.1-0.4-0.4-0.5-0.4-0.4-0.50.3-1.20.2-0.7-1.9-0.8-1.8-1.91.1-2.1-2.01.4-2.22.8
Length without tail0.41.02.6-0.91.21.10.50.61.21.20.91.21.21.0-0.90.6-1.2-1.40.1-1.50.20.11.6-0.00.01.6-0.10.7
Times rat made contact with spout1.82.13.21.3-1.4-1.3-1.7-1.3-1.6-1.6-1.5-1.4-1.4-1.41.3-1.81.61.1-1.51.1-1.6-1.6-0.9-1.6-1.6-0.8-1.71.5
Lifetime Intake1.92.13.4-1.71.31.31.51.81.31.31.51.41.41.4-1.41.5-1.0-1.11.9-1.11.71.80.91.81.60.81.7-1.7
Liver weight, left0.71.03.10.6-0.5-0.4-1.6-1.1-0.5-0.5-0.6-0.6-0.6-0.60.4-1.10.90.0-1.4-0.1-1.5-1.50.3-1.6-1.40.6-1.81.7
Liver weight, right0.20.31.3-0.30.30.6-0.7-0.20.40.40.20.40.40.2-0.3-0.10.0-0.7-0.5-0.7-0.6-0.71.0-0.8-0.51.1-0.90.9
Locomotor activity0.30.61.1-1.00.70.90.31.00.50.50.80.70.70.6-0.90.8-0.1-0.71.1-0.70.80.80.80.90.70.80.6-0.6
Locomotor testing distance0.00.10.2-0.20.10.20.20.30.20.20.10.30.30.2-0.20.3-0.1-0.10.4-0.10.30.30.10.40.30.10.3-0.2
Locomotor testing rearing0.81.32.2-1.00.90.91.31.21.21.21.11.01.01.0-0.91.3-0.9-0.71.5-0.71.41.40.51.51.40.41.4-1.4
Locomotion in novel chamber0.70.82.90.4-0.6-0.40.60.3-0.4-0.4-0.2-0.3-0.3-0.30.50.50.51.11.01.20.91.0-1.51.21.1-1.71.3-1.7
Locomotion in novel chamber post-restriction0.20.20.4-0.30.30.30.50.50.50.50.30.60.60.4-0.20.5-0.6-0.20.4-0.20.50.50.10.50.6-0.00.6-0.4
Fecal boli incidents, locomotor time 10.10.10.30.5-0.2-0.2-0.3-0.5-0.1-0.1-0.4-0.3-0.3-0.20.3-0.4-0.00.2-0.60.2-0.4-0.5-0.2-0.5-0.5-0.1-0.40.6
Change in fecal boli incidents, locomotor task0.60.50.70.8-0.8-0.8-0.7-0.8-0.8-0.8-0.7-0.6-0.6-0.70.7-0.80.80.7-0.80.7-0.8-0.8-0.6-0.8-0.7-0.5-0.80.8
Time >=10cm from walls, locomotor time 10.10.10.2-0.30.10.40.50.50.20.20.10.40.40.3-0.20.1-0.3-0.10.2-0.10.30.30.00.30.4-0.00.3-0.4
Bouts of movement, locomotor time 10.20.20.8-0.40.50.50.40.30.90.90.30.40.40.5-0.40.2-0.5-0.40.1-0.40.30.20.40.20.30.40.30.0
Total resting periods, locomotor time 10.20.20.8-0.40.50.60.50.40.90.90.40.50.50.6-0.40.4-0.5-0.40.3-0.40.40.40.40.30.40.30.4-0.1
Rest time, locomotor task time 10.10.10.3-0.10.10.20.50.20.50.50.20.10.10.20.00.3-0.30.20.30.20.40.4-0.30.40.4-0.40.6-0.4
Distance moved, locomotor task time 10.20.20.4-0.50.50.30.40.60.40.40.50.50.50.4-0.60.5-0.3-0.50.6-0.50.50.60.40.60.50.40.5-0.5
Vertical activity count, locomotor time 10.70.71.0-0.80.90.70.90.90.90.90.80.80.80.9-0.90.8-1.0-0.80.8-0.80.90.90.80.80.80.70.8-0.8
Time >=10cm from walls, locomotor time 20.40.41.10.5-0.9-0.3-0.8-0.3-0.9-0.9-0.8-0.4-0.4-0.70.5-0.91.00.8-0.50.8-0.6-0.6-0.7-0.5-0.4-0.7-0.60.4
Bouts of movement, locomotor time 20.00.00.2-0.0-0.1-0.3-0.4-0.10.00.0-0.1-0.4-0.4-0.10.0-0.20.4-0.00.0-0.0-0.1-0.10.1-0.1-0.30.1-0.20.2
Total resting periods, locomotor time 20.00.10.2-0.30.2-0.00.00.20.30.30.2-0.1-0.10.2-0.3-0.00.0-0.30.2-0.30.10.10.40.1-0.00.40.00.0
Rest time, locomotor task time 20.40.40.9-0.70.60.50.50.60.60.60.90.50.50.6-0.60.9-0.3-0.50.9-0.50.80.80.40.90.60.40.8-0.6
Distance moved, locomotor task time 20.10.10.30.1-0.0-0.10.50.2-0.0-0.00.10.00.00.1-0.10.2-0.30.20.30.30.40.4-0.40.40.3-0.50.6-0.5
Vertical activity count, locomotor time 20.70.71.01.0-0.8-0.9-0.6-0.9-0.7-0.7-0.9-1.0-1.0-0.80.8-1.00.40.8-1.00.8-0.8-0.8-0.8-0.9-0.9-0.8-0.70.8
Light reinforcement 10.10.10.3-0.20.30.20.30.30.50.50.40.40.40.3-0.30.5-0.3-0.20.4-0.20.40.40.20.40.40.20.3-0.3
Light reinforcement 23.04.04.72.0-2.1-2.0-2.1-2.0-2.1-2.1-2.0-2.2-2.2-2.11.9-2.22.12.0-2.02.0-2.0-2.0-1.9-1.9-2.0-1.7-1.81.8
Bone: marrow area0.30.61.1-0.90.70.80.71.00.60.60.90.60.60.8-0.90.8-0.6-0.61.1-0.61.01.00.51.00.80.50.9-0.9
Bone: maximum diameter0.51.02.7-0.80.60.91.01.20.70.70.90.80.80.8-0.91.1-0.5-0.31.5-0.21.31.40.11.51.4-0.01.4-1.6
Bone: maximum force1.32.33.91.3-1.5-1.4-1.8-1.3-1.6-1.6-1.7-1.6-1.6-1.51.3-2.01.51.3-1.61.3-1.6-1.6-1.1-1.6-1.6-1.0-1.61.5
Bone: maximum moment1.11.93.21.2-1.4-1.3-1.6-1.2-1.5-1.5-1.5-1.5-1.5-1.41.2-1.81.41.2-1.41.2-1.4-1.4-1.1-1.4-1.4-1.0-1.41.2
Mean time between licks in bursts0.30.41.20.4-0.2-0.4-0.8-0.7-0.5-0.5-0.4-0.4-0.4-0.40.4-0.70.3-0.0-0.8-0.1-0.8-0.90.2-0.9-0.90.3-1.01.1
Mean num. licks in bursts0.30.41.00.2-0.4-0.4-0.8-0.3-0.6-0.6-0.7-0.4-0.4-0.40.3-1.00.50.1-0.80.1-0.8-0.80.0-0.8-0.70.1-1.00.9
Cd content in liver1.82.03.2-1.51.61.41.31.21.31.31.81.31.31.5-1.61.7-1.3-1.51.5-1.51.41.41.41.41.21.31.3-1.1
Co content in liver0.00.00.2-0.1-0.2-0.2-0.30.2-0.2-0.2-0.0-0.2-0.2-0.1-0.1-0.10.40.10.20.10.00.1-0.10.20.0-0.1-0.0-0.1
Cu content in liver1.21.52.30.9-1.1-1.4-1.4-1.0-1.5-1.5-1.2-1.4-1.4-1.31.1-1.41.40.9-1.00.9-1.2-1.1-0.8-1.1-1.4-0.7-1.21.2
Fe content in liver0.30.41.20.3-0.2-0.3-0.7-0.6-0.4-0.4-0.3-0.4-0.4-0.40.3-0.60.3-0.1-0.9-0.1-0.9-0.90.3-0.9-0.90.4-1.01.1
K content in liver1.61.63.31.0-1.0-1.1-1.5-1.2-1.0-1.0-1.3-1.0-1.0-1.00.8-1.70.90.6-1.70.5-1.6-1.7-0.3-1.8-1.6-0.2-1.81.8
Mg content in liver0.00.00.1-0.1-0.1-0.00.20.3-0.0-0.0-0.0-0.0-0.00.1-0.1-0.1-0.10.10.20.10.20.2-0.20.20.2-0.20.2-0.3
Mn content in liver0.00.10.4-0.10.20.10.40.20.30.30.10.20.20.3-0.10.0-0.6-0.2-0.0-0.20.20.20.10.10.10.10.20.1
Na content in liver3.43.64.91.9-2.0-1.9-2.0-1.8-2.2-2.2-2.0-2.0-2.0-2.01.9-2.02.01.8-1.81.8-1.8-1.8-1.7-1.7-1.8-1.6-1.71.5
Rb content in liver2.53.13.7-1.81.71.71.91.91.81.81.81.81.81.8-1.91.8-1.7-1.51.9-1.51.91.91.31.81.91.21.8-1.8
Se content in liver1.51.82.51.3-1.4-1.5-1.4-1.3-1.6-1.6-1.3-1.5-1.5-1.41.3-1.41.31.3-1.31.2-1.3-1.3-1.2-1.2-1.4-1.1-1.21.2
Sr content in liver0.50.50.8-0.70.80.80.80.60.80.80.70.80.80.8-0.70.7-0.9-0.80.5-0.80.60.50.80.50.60.70.5-0.4
Zn content in liver0.70.81.1-0.90.80.81.01.10.90.90.80.80.80.9-0.80.9-0.9-0.71.0-0.61.01.00.51.11.00.41.0-0.9
Bone: minimum diameter0.61.12.30.8-1.0-1.0-1.5-0.9-1.3-1.3-0.8-1.3-1.3-1.10.8-1.11.50.8-0.70.9-1.0-0.9-0.7-0.8-1.1-0.6-1.00.8
Time in familiar zone, hab. session 11.71.62.5-1.21.11.21.51.41.21.21.21.11.11.2-1.11.4-1.3-0.81.4-0.81.51.50.61.51.50.41.6-1.6
Time in novel zone, hab. session 11.11.11.90.9-0.9-1.0-1.4-1.2-1.0-1.0-0.9-1.0-1.0-1.10.9-1.01.20.7-1.10.6-1.3-1.2-0.5-1.2-1.3-0.3-1.31.2
Total zone transitions, hab. session 13.24.45.9-2.12.12.12.42.12.12.12.22.12.12.1-2.02.4-2.1-1.82.2-1.72.32.31.52.22.31.32.3-2.2
Total locomotion distance, hab. session 10.91.21.7-1.11.21.11.31.11.11.11.31.11.11.1-1.11.3-1.1-1.01.1-1.01.11.10.91.11.00.91.1-0.9
Locomotion velocity, hab. session 10.81.11.8-1.01.11.11.31.01.01.01.21.01.01.1-1.01.2-1.2-0.91.0-0.91.11.10.81.01.00.71.1-0.9
Time in familiar zone, hab. session 22.42.43.0-1.61.61.61.71.61.61.61.71.61.61.6-1.61.7-1.7-1.51.6-1.41.61.61.31.51.51.21.6-1.2
Time in novel zone, hab. session 25.75.76.72.4-2.5-2.5-2.6-2.4-2.5-2.5-2.6-2.5-2.5-2.52.4-2.52.62.2-2.32.2-2.4-2.4-2.0-2.3-2.3-1.9-2.31.8
Total zone transitions, hab. session 21.11.42.2-1.01.31.51.30.91.41.41.21.51.51.3-1.21.3-1.4-1.30.9-1.31.00.91.20.81.11.20.9-0.7
Total locomotion distance, hab. session 20.00.00.20.3-0.00.00.0-0.3-0.1-0.1-0.1-0.1-0.1-0.00.1-0.1-0.2-0.0-0.4-0.1-0.3-0.30.1-0.4-0.30.1-0.30.5
Locomotion velocity, hab. session 20.00.10.20.3-0.1-0.1-0.0-0.4-0.2-0.2-0.2-0.2-0.2-0.10.2-0.2-0.10.1-0.50.0-0.3-0.4-0.0-0.4-0.4-0.0-0.30.5
Novel to familiar place preference ratio0.20.20.6-0.40.00.00.40.70.20.20.20.20.20.1-0.20.20.10.10.70.10.60.6-0.20.70.6-0.20.6-0.7
Novelty place preference0.00.00.3-0.30.0-0.00.10.50.10.10.10.10.10.0-0.1-0.00.10.00.40.00.30.3-0.10.40.3-0.10.2-0.4
Time in novel zone, NPP test0.10.10.5-0.50.30.20.30.70.30.30.30.30.30.3-0.40.2-0.1-0.30.5-0.20.40.40.20.50.40.20.3-0.4
Total zone transitions, NPP test1.92.73.6-1.51.61.91.81.61.71.71.71.71.71.7-1.61.9-1.6-1.41.6-1.41.71.61.21.61.81.11.6-1.6
Total locomotion distance, NPP test0.50.71.3-0.60.70.81.10.80.60.60.90.70.70.8-0.71.1-0.7-0.41.0-0.41.01.00.31.11.00.11.1-1.1
Locomotion velocity, NPP test0.30.41.2-0.20.30.40.90.40.30.30.50.30.30.4-0.30.8-0.40.00.80.10.80.9-0.20.90.8-0.41.0-1.1
Intraocular pressure1.82.56.1-1.31.21.31.61.61.01.01.71.11.11.3-1.52.0-0.9-0.72.3-0.62.12.20.42.32.10.22.2-2.5
Delta distance traveled before/after self-admin0.80.92.4-1.01.11.10.60.71.01.00.90.90.91.0-1.10.4-1.1-1.40.3-1.40.40.31.50.20.21.60.10.1
Delta ambulatory time before/after self-admin0.50.51.5-0.70.90.80.50.40.90.90.70.70.70.8-0.80.2-1.0-1.10.1-1.10.20.11.2-0.00.11.2-0.00.3
Parametrial fat weight3.87.416.6-2.93.23.01.92.23.33.32.63.23.23.0-3.01.9-3.3-3.71.1-3.81.31.14.00.81.24.10.60.2
Pavlov. Cond. lever latency0.40.51.3-0.60.60.51.00.70.60.60.80.60.60.6-0.60.9-0.6-0.30.9-0.30.90.90.20.91.00.11.0-1.1
Pavlov. Cond. magazine entry latency0.20.21.00.00.0-0.0-0.4-0.3-0.1-0.1-0.3-0.2-0.2-0.10.1-0.5-0.1-0.3-0.7-0.3-0.6-0.60.5-0.7-0.70.6-0.81.0
Pavlov. Cond. change in total contacts0.80.81.21.0-0.9-0.9-1.0-1.1-0.9-0.9-1.0-1.0-1.0-1.01.0-0.90.90.9-0.90.9-0.9-0.9-0.8-0.8-0.9-0.8-0.80.8
Pavlov. Cond. index score0.30.41.80.3-0.2-0.2-0.8-0.5-0.3-0.3-0.5-0.3-0.3-0.30.3-0.80.1-0.1-1.0-0.2-0.9-0.90.3-1.0-1.00.4-1.01.3
Pavlov. Cond. latency score0.50.62.40.4-0.3-0.4-1.0-0.7-0.5-0.5-0.7-0.5-0.5-0.50.5-1.00.3-0.1-1.2-0.1-1.1-1.20.3-1.3-1.20.5-1.31.6
Pavlov. Cond. lever contacts0.40.41.00.5-0.4-0.5-0.9-0.7-0.6-0.6-0.7-0.6-0.6-0.50.5-0.80.50.2-0.80.2-0.8-0.8-0.1-0.9-0.90.0-0.91.0
Pavlov. Cond. magazine entry number0.10.10.4-0.20.00.10.20.30.10.10.20.20.20.1-0.20.30.10.10.40.10.30.4-0.20.50.5-0.20.4-0.7
Pavlov. Cond. intertrial magazine entries1.11.32.5-0.90.91.01.31.10.90.91.31.11.11.1-1.11.4-0.9-0.61.5-0.61.51.50.41.51.40.21.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.20.31.40.2-0.1-0.2-0.6-0.4-0.3-0.3-0.5-0.3-0.3-0.20.3-0.70.0-0.1-0.8-0.2-0.7-0.80.3-0.9-0.80.4-0.91.2
Pavlov. Cond. response bias0.10.10.70.2-0.0-0.1-0.4-0.3-0.1-0.1-0.3-0.1-0.1-0.10.1-0.4-0.0-0.1-0.5-0.2-0.5-0.50.3-0.6-0.60.3-0.60.8
Pavlov. Cond. lever latency0.30.41.2-0.60.80.60.50.40.60.60.40.50.50.6-0.50.2-1.0-1.0-0.1-1.00.10.01.1-0.1-0.01.1-0.10.3
Pavlov. Cond. magazine entry latency1.21.32.21.2-1.3-1.1-1.5-1.2-1.2-1.2-1.1-1.0-1.0-1.31.1-1.11.41.1-1.11.1-1.3-1.2-1.0-1.2-1.1-0.9-1.21.1
Pavlov. Cond. change in total contacts0.50.61.20.7-1.0-0.9-0.9-0.5-0.9-0.9-0.8-0.8-0.8-0.90.7-0.81.10.9-0.51.0-0.6-0.6-0.9-0.5-0.6-0.9-0.50.4
Pavlov. Cond. index score0.60.71.71.0-1.1-0.9-0.8-0.7-0.9-0.9-0.7-0.8-0.8-1.00.8-0.51.21.3-0.31.3-0.5-0.4-1.3-0.2-0.3-1.3-0.30.1
Pavlov. Cond. latency score0.80.92.31.1-1.3-1.0-0.9-0.8-1.0-1.0-0.8-0.9-0.9-1.11.0-0.61.31.4-0.41.5-0.5-0.4-1.5-0.3-0.4-1.5-0.30.1
Pavlov. Cond. lever contacts0.30.51.00.8-0.9-0.7-0.7-0.7-0.7-0.7-0.5-0.7-0.7-0.70.6-0.51.00.9-0.41.0-0.5-0.4-0.9-0.3-0.4-0.9-0.40.2
Pavlov. Cond. magazine entry number1.21.42.2-1.21.41.21.51.11.21.21.21.21.21.3-1.11.2-1.4-1.31.1-1.31.21.21.21.11.11.11.1-1.0
Pavlov. Cond. intertrial magazine entries2.53.24.0-1.92.01.91.91.81.71.71.91.81.81.9-1.91.8-1.9-1.91.8-1.91.81.81.81.71.61.71.6-1.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.71.0-1.1-0.8-0.8-0.7-0.8-0.8-0.7-0.7-0.7-0.90.8-0.51.11.2-0.31.2-0.4-0.4-1.3-0.2-0.3-1.3-0.20.0
Pavlov. Cond. response bias0.60.81.71.0-1.1-0.9-1.1-0.9-0.9-0.9-0.7-0.9-0.9-1.00.8-0.71.31.1-0.61.1-0.7-0.7-1.1-0.6-0.6-1.0-0.60.5
Time in closed arm before self-admin0.40.41.4-0.60.70.50.30.20.70.70.20.30.30.6-0.4-0.1-1.1-1.0-0.5-1.1-0.2-0.31.1-0.5-0.41.2-0.40.8
Time in closed arm after self-admin0.30.30.70.4-0.3-0.8-0.5-0.6-0.5-0.5-0.5-0.8-0.8-0.50.5-0.70.30.3-0.80.3-0.7-0.7-0.3-0.7-0.8-0.2-0.50.7
Time in open arm before self-admin2.22.35.81.6-1.9-1.6-1.5-1.3-2.1-2.1-1.2-1.4-1.4-1.71.4-1.02.42.0-0.62.1-1.0-0.8-2.0-0.5-0.7-2.0-0.70.2
Time in open arm after self-admin0.20.20.80.3-0.60.2-0.40.0-0.5-0.5-0.20.20.2-0.40.20.30.90.70.50.70.20.3-0.70.50.6-0.70.2-0.8
Bone: periosteal estimation0.10.20.50.3-0.5-0.3-0.5-0.1-0.6-0.6-0.2-0.5-0.5-0.40.2-0.30.70.50.20.5-0.00.0-0.50.1-0.1-0.5-0.0-0.2
Bone: periosteal perimeter0.30.51.5-0.70.40.60.51.00.30.30.60.30.30.4-0.60.7-0.1-0.21.1-0.20.91.00.11.10.90.00.9-1.2
Bone: post-yield work0.10.10.4-0.30.30.3-0.10.10.20.20.30.30.30.3-0.40.0-0.2-0.5-0.1-0.5-0.2-0.20.6-0.2-0.10.6-0.30.4
Progressive ratio test 1 active lever presses2.12.23.7-1.91.61.41.21.81.31.31.71.21.21.5-1.81.3-0.8-1.71.7-1.61.41.51.61.51.21.71.2-1.3
Progressive ratio test 1 breakpoint3.13.25.4-2.32.01.81.52.11.61.62.01.51.51.8-2.21.5-1.1-2.11.9-2.11.61.72.11.71.32.11.3-1.4
Progressive ratio test 1 inactive lever presses0.10.10.3-0.50.10.10.00.5-0.1-0.10.2-0.2-0.20.1-0.4-0.10.6-0.10.5-0.00.30.30.00.50.20.10.3-0.6
Progressive ratio test 2 active lever presses2.62.84.6-2.11.71.71.22.11.21.21.91.51.51.5-2.01.7-0.8-1.72.1-1.61.81.91.61.91.61.51.6-1.8
Progressive ratio test 2 breakpoint2.52.94.8-2.11.71.71.32.11.21.21.91.51.51.5-2.01.7-0.8-1.62.2-1.61.81.91.52.01.61.51.7-1.9
Progressive ratio test 2 inactive lever presses1.72.03.7-1.71.31.41.11.80.70.71.61.31.31.2-1.61.5-0.4-1.21.9-1.11.51.61.11.81.51.11.5-1.7
Incentive Sensitization - Responses1.61.73.1-1.61.31.50.61.60.60.61.51.31.31.1-1.61.4-0.3-1.31.8-1.21.31.41.21.51.31.21.2-1.4
Incentive Sensitization - Breakpoint1.21.22.4-1.41.11.30.51.30.50.51.31.11.10.9-1.41.2-0.2-1.11.6-1.11.21.21.11.41.11.11.0-1.3
Sum of active levers in priming session hrs 5-62.42.35.1-1.91.71.80.91.61.71.71.61.71.71.5-1.81.2-1.0-2.01.2-2.01.00.92.20.90.92.30.5-0.5
Progressive ratio0.40.51.0-0.60.60.81.00.80.80.80.40.60.60.8-0.60.5-0.8-0.40.6-0.40.80.80.30.70.80.20.9-0.8
Food seeking constrained by brief footshock0.30.30.50.6-0.5-0.6-0.4-0.6-0.6-0.6-0.5-0.7-0.7-0.50.5-0.60.40.6-0.60.6-0.5-0.5-0.6-0.5-0.6-0.6-0.40.5
Seeking ratio, punishment vs. effort1.21.51.91.2-1.2-1.3-1.3-1.4-1.4-1.4-1.0-1.2-1.2-1.31.2-1.11.21.0-1.21.0-1.3-1.3-0.9-1.2-1.3-0.8-1.21.3
Retroperitoneal fat weight0.00.10.3-0.0-0.00.20.10.10.40.40.30.30.30.1-0.10.50.20.00.30.10.20.2-0.00.30.4-0.00.1-0.4
Reaction time number correct0.00.10.2-0.30.30.20.10.3-0.1-0.10.30.20.20.3-0.40.0-0.2-0.30.3-0.30.20.20.30.20.10.40.1-0.1
Reaction time mean minus median0.10.10.60.3-0.3-0.50.3-0.20.20.2-0.2-0.4-0.4-0.20.50.0-0.10.6-0.10.50.10.1-0.70.10.1-0.80.3-0.3
Reaction time mean minus median AUC0.81.02.2-0.90.90.61.50.91.31.30.90.70.71.0-0.71.1-1.3-0.51.0-0.51.21.20.31.11.10.11.4-1.2
Reaction time num false alarms0.81.13.3-0.70.60.71.31.10.90.90.90.70.70.8-0.71.2-0.8-0.21.4-0.11.41.5-0.11.51.5-0.31.6-1.8
Reaction time num false alarms AUC0.70.92.9-0.60.50.71.31.00.70.70.70.60.60.7-0.71.1-0.7-0.11.3-0.11.31.3-0.11.41.4-0.31.5-1.7
Reaction time trials correct on left0.00.10.2-0.30.30.20.10.3-0.1-0.10.30.20.20.3-0.40.0-0.2-0.30.3-0.30.20.20.30.20.10.40.1-0.1
Reaction time trials on left0.00.10.1-0.30.20.20.20.3-0.0-0.00.30.20.20.3-0.40.0-0.2-0.30.3-0.30.20.20.30.20.10.30.1-0.2
Reaction time mean0.20.30.60.7-0.6-0.6-0.5-0.7-0.2-0.2-0.5-0.7-0.7-0.60.7-0.30.40.7-0.60.7-0.5-0.5-0.7-0.5-0.4-0.8-0.30.3
Reaction time mean AUC0.30.41.20.8-0.8-0.7-0.4-0.8-0.3-0.3-0.6-0.8-0.8-0.70.8-0.30.51.0-0.50.9-0.4-0.4-1.0-0.4-0.3-1.1-0.20.1
Median of all reaction times0.40.50.80.8-0.8-0.7-0.8-0.9-0.4-0.4-0.7-0.8-0.8-0.70.8-0.50.70.8-0.70.8-0.7-0.7-0.8-0.7-0.6-0.8-0.60.4
Reaction time omissions0.10.10.30.4-0.5-0.5-0.2-0.4-0.1-0.1-0.5-0.2-0.2-0.40.6-0.30.20.5-0.40.5-0.3-0.3-0.5-0.3-0.2-0.5-0.30.3
Reaction time false alarm rate0.50.72.1-0.50.40.61.10.80.80.80.50.50.50.6-0.51.0-0.6-0.11.0-0.01.11.1-0.21.11.2-0.31.3-1.4
Reaction time premature initiation rate0.70.91.4-1.11.11.00.91.01.11.10.91.01.01.1-1.20.8-0.9-1.10.7-1.10.70.71.10.60.71.10.6-0.4
Reaction time premature initiations0.81.21.9-1.31.21.21.01.21.11.11.21.11.11.2-1.40.9-1.1-1.20.9-1.20.90.91.20.80.81.20.7-0.6
Std. dev. reaction times0.20.20.90.5-0.5-0.60.2-0.40.10.1-0.4-0.6-0.6-0.30.6-0.2-0.00.7-0.30.7-0.1-0.1-0.9-0.1-0.1-1.00.1-0.1
Reaction time trials completed0.00.10.1-0.30.20.20.20.3-0.0-0.00.30.20.20.3-0.40.0-0.2-0.30.3-0.30.20.20.30.20.10.30.1-0.2
Reaction time trials AUC0.00.10.2-0.30.30.20.20.4-0.1-0.10.30.20.20.3-0.40.0-0.2-0.30.3-0.30.30.30.30.30.10.30.2-0.2
Run reversals in cocaine runway, females0.10.10.2-0.10.0-0.20.40.1-0.1-0.10.1-0.1-0.10.00.00.3-0.10.20.20.20.30.3-0.30.30.3-0.40.5-0.5
Run reversals in cocaine runway, males0.80.82.0-0.80.60.61.11.00.90.90.70.70.70.6-0.41.1-0.6-0.21.3-0.21.21.30.01.31.2-0.11.3-1.4
Latency to leave start box in cocaine runway0.50.61.00.7-0.6-0.8-0.6-0.8-0.6-0.6-0.8-0.8-0.8-0.70.7-1.00.50.6-0.90.5-0.8-0.8-0.5-0.9-1.0-0.4-0.81.0
Latency to leave start box in cocaine runway, F1.31.42.81.1-0.9-1.2-1.0-1.3-1.0-1.0-1.3-1.2-1.2-1.01.1-1.50.60.7-1.70.7-1.4-1.5-0.6-1.6-1.5-0.5-1.41.6
Latency to leave start box in cocaine runway, M0.00.00.1-0.20.00.10.10.20.10.1-0.10.00.00.0-0.1-0.1-0.0-0.10.1-0.10.10.10.20.1-0.00.2-0.10.1
Std. dev. time between licks in bursts0.30.30.7-0.50.60.60.70.50.80.80.50.70.70.6-0.50.6-0.7-0.50.5-0.50.60.60.50.50.60.40.5-0.5
Total sessions with >9 infusions0.50.51.1-1.00.70.60.71.00.80.80.70.60.60.7-0.80.4-0.5-0.80.8-0.70.70.70.70.70.50.70.6-0.5
Short access day 1 total inactive lever presses0.20.20.3-0.50.50.40.40.50.60.60.30.60.60.5-0.50.1-0.5-0.50.3-0.50.30.30.50.30.20.50.2-0.1
Short access day 10 total inactive lever presses0.40.40.80.4-0.5-0.4-0.9-0.5-0.8-0.8-0.6-0.5-0.5-0.60.4-0.90.70.3-0.60.3-0.8-0.7-0.2-0.7-0.8-0.0-0.80.8
Short access day 1 total infusions0.60.72.1-0.90.60.41.01.20.30.30.70.30.30.6-0.70.7-0.3-0.31.3-0.21.21.20.01.30.9-0.11.3-1.4
Short access day 10 total infusions3.33.66.0-2.21.81.61.72.41.61.62.01.81.81.8-2.02.0-1.2-1.72.4-1.62.22.21.52.32.01.42.0-2.2
Short access total infusions1.41.52.9-1.41.10.91.41.61.01.01.20.90.91.1-1.11.2-0.9-0.81.7-0.71.61.60.61.71.30.41.6-1.7
Short access day 1 locomotion0.20.20.8-0.50.20.00.50.80.00.00.2-0.0-0.00.1-0.30.10.1-0.00.90.00.70.8-0.10.90.4-0.10.7-0.9
Short access day 10 total locomotion0.10.20.6-0.0-0.4-0.3-0.50.2-0.8-0.8-0.4-0.5-0.5-0.50.2-0.50.80.40.10.4-0.1-0.1-0.40.0-0.3-0.3-0.1-0.0
Short access total locomotion0.20.20.7-0.60.1-0.00.30.8-0.1-0.10.2-0.2-0.20.1-0.4-0.10.2-0.10.80.00.60.6-0.00.70.2-0.10.6-0.7
One hour access (0.3 mA shock)3.33.95.3-2.11.92.02.12.31.71.72.01.91.91.9-1.92.2-1.6-1.72.3-1.62.22.21.52.22.11.32.1-2.1
Compulsive drug intake1.01.02.51.0-0.8-0.5-1.0-1.2-0.8-0.8-0.9-0.5-0.5-0.80.8-0.90.40.5-1.60.4-1.4-1.4-0.3-1.6-1.2-0.2-1.41.6
One hour access (shock baseline)3.54.07.2-2.21.91.82.02.41.71.72.11.61.61.9-2.02.1-1.3-1.62.7-1.52.42.51.42.62.21.22.3-2.4
Social response proportion0.60.72.6-0.60.60.4-0.30.10.40.40.10.50.50.4-0.5-0.5-0.6-1.1-0.8-1.2-0.7-0.81.4-1.0-0.81.6-1.11.4
Social responses0.70.82.4-1.01.10.90.60.71.01.00.71.01.01.0-1.00.4-1.2-1.40.1-1.40.30.21.50.00.21.6-0.10.3
Social time0.81.03.4-0.81.10.81.10.51.71.70.61.21.21.2-0.70.5-1.8-1.2-0.2-1.30.20.11.3-0.20.21.30.00.6
Soleus weight2.16.314.1-3.13.02.81.72.42.62.62.62.72.72.8-3.01.9-2.7-3.51.4-3.51.41.33.71.01.23.80.7-0.3
Bone: stiffness0.30.41.6-0.80.60.7-0.20.50.50.50.40.50.50.6-0.8-0.2-0.6-1.0-0.2-1.0-0.1-0.21.1-0.3-0.31.3-0.50.7
Tibialis anterior weight8.830.137.2-5.85.96.05.65.66.16.15.66.06.06.0-5.95.2-6.1-5.84.7-5.85.04.85.54.54.95.34.4-3.6
Time to tail flick, vehicle, before self-admin4.74.87.0-2.32.52.42.12.02.22.22.32.52.52.4-2.42.0-2.5-2.61.7-2.61.81.72.61.51.72.61.4-1.0
Time to tail flick, vehicle, after self-admin1.01.12.4-0.81.10.81.60.91.01.01.11.21.21.1-0.91.2-1.4-0.81.0-0.81.21.10.61.11.20.41.3-1.0
Time to tail flick, test, before self-admin0.20.20.80.40.1-0.20.3-0.60.20.2-0.3-0.1-0.10.10.2-0.4-0.80.0-0.9-0.1-0.4-0.50.0-0.7-0.5-0.0-0.30.8
Time to tail flick, test, after self-admin0.10.10.30.3-0.0-0.1-0.0-0.50.10.1-0.10.10.1-0.00.2-0.0-0.2-0.1-0.6-0.1-0.4-0.50.2-0.6-0.20.2-0.50.5
Delta time to tail flick, vehicle, before/after SA0.70.72.81.1-1.0-1.10.0-0.8-0.5-0.5-0.8-0.9-0.9-0.71.0-0.50.41.3-0.51.3-0.2-0.2-1.5-0.2-0.2-1.70.2-0.2
Delta time to tail flick, test, before/after SA0.70.71.4-0.90.60.80.71.00.40.40.80.80.80.6-0.71.1-0.2-0.61.2-0.50.91.00.51.11.10.50.8-1.2
Tibia length1.43.98.11.8-1.6-1.5-2.4-2.2-1.4-1.4-1.9-1.5-1.5-1.71.7-2.31.51.1-2.71.0-2.6-2.7-0.7-2.8-2.4-0.5-2.72.8
Ambulatory time before self-admin2.22.23.81.5-1.8-1.6-1.6-1.4-1.5-1.5-1.6-1.5-1.5-1.71.6-1.41.91.7-1.31.7-1.4-1.4-1.6-1.2-1.2-1.5-1.31.0
Ambulatory time after self-admin0.50.61.80.3-0.4-0.5-1.0-0.6-0.2-0.2-0.6-0.6-0.6-0.50.4-1.00.60.1-1.00.0-1.1-1.10.2-1.2-1.10.3-1.31.3
Bone: tissue strength3.23.14.21.6-1.9-1.8-1.8-1.6-2.1-2.1-2.0-1.9-1.9-1.81.8-2.01.81.7-1.71.7-1.7-1.7-1.6-1.6-1.6-1.5-1.61.3
Total heroin consumption3.33.98.9-2.22.32.41.41.82.22.21.92.42.42.1-2.21.5-1.8-2.71.0-2.71.00.92.90.71.13.00.4-0.2
Bone: trabecular number4.36.78.7-2.72.82.92.72.32.82.82.82.92.92.8-2.72.8-2.9-2.82.1-2.82.22.12.71.92.32.61.9-1.9
Bone: trabecular spacing0.30.40.90.6-0.8-0.7-0.7-0.3-0.8-0.8-0.6-0.7-0.7-0.70.5-0.80.90.8-0.10.8-0.3-0.2-0.8-0.1-0.4-0.8-0.20.2
Bone: trabecular thickness0.10.10.5-0.20.30.40.40.20.70.70.20.30.30.4-0.20.3-0.7-0.3-0.1-0.30.10.10.3-0.00.20.30.1-0.1
Bone: trabecular tissue density2.23.14.32.0-1.9-2.1-1.6-1.9-1.7-1.7-1.8-1.8-1.8-1.92.1-1.51.82.0-1.42.0-1.4-1.4-2.0-1.3-1.4-2.0-1.11.1
Water consumed over 24 hours1.01.32.70.8-0.8-1.0-1.3-1.1-1.0-1.0-1.0-1.1-1.1-1.00.8-1.40.80.5-1.50.5-1.4-1.5-0.3-1.5-1.5-0.2-1.51.6
Number of responses in last shaping day0.30.30.80.2-0.6-0.4-0.20.2-0.6-0.6-0.4-0.5-0.5-0.40.3-0.20.70.70.40.80.30.3-0.90.50.2-0.90.4-0.7