Rap1gap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Rap1gap2 0.07 0.04 1.1e-09 0.06 0.06 0.06 0.06 8.2e-10 2.1e-09 9.1e-10 1.1e-09
2 PL gene expression Rap1gap2 0.38 0.14 0.0e+00 0.4 0.38 0.39 0.4 1.1e-46 1.4e-43 8.8e-46 1.7e-46
3 PL mRNA stability Rap1gap2 0.08 0.05 6.6e-10 0.1 0.09 0.1 0.1 1.1e-10 2.5e-10 1.2e-10 1.1e-10
4 IC intron excision ratio chr10_59855162_59892814 0.15 0.09 3.7e-05 0.1 0.12 0.06 0.11 8.2e-05 7.7e-06 1.6e-03 1.9e-05
5 IC gene expression Rap1gap2 0.59 0.14 0.0e+00 0.55 0.54 0.56 0.55 2.2e-27 1.0e-26 7.9e-28 4.5e-27
6 IC alternative TSS NM_001401654.1 0.08 0.06 6.0e-03 0.03 0.03 0.01 0.03 1.7e-02 1.4e-02 1.4e-01 2.0e-02
7 BLA gene expression Rap1gap2 0.25 0.12 1.9e-11 0.19 0.18 0.19 0.2 1.4e-10 7.1e-10 2.3e-10 1.4e-10
8 PL isoform ratio NM_001401654.1 0.04 0.03 2.2e-05 0.04 0.04 0.03 0.04 9.8e-06 1.2e-05 2.3e-04 2.9e-05
9 PL intron excision ratio chr10_59855162_59892814 0.07 0.05 1.4e-08 0.06 0.06 0.07 0.07 2.0e-07 3.3e-07 6.7e-08 9.4e-08
10 BLA alternative TSS NM_001401654.1 0.09 0.06 5.7e-04 0.06 0.04 0.03 0.03 6.1e-04 5.0e-03 1.4e-02 8.3e-03
11 BLA isoform ratio NM_001401654.1 0.06 0.04 5.0e-03 0.04 0.02 0.01 0.02 5.2e-03 3.8e-02 7.2e-02 3.1e-02
12 PL alternative TSS NM_001401654.1 0.04 0.03 1.7e-04 0.04 0.04 0.03 0.03 5.2e-05 9.3e-05 6.8e-04 1.5e-04
13 OFC gene expression Rap1gap2 0.67 0.15 1.4e-12 0.43 0.46 0.47 0.45 2.1e-11 2.8e-12 1.3e-12 5.8e-12
14 IL gene expression Rap1gap2 0.81 0.07 2.0e-12 0.31 0.32 0.38 0.16 2.9e-08 2.2e-08 5.5e-10 1.3e-04
15 Brain gene expression Rap1gap2 0.38 0.07 0.0e+00 0.52 0.53 0.54 0.54 9.6e-56 7.8e-58 1.1e-58 2.6e-59
16 PL alternative TSS XM_063269050.1 0.07 0.06 3.2e-06 0.04 0.05 0.05 0.05 2.4e-05 3.7e-06 4.5e-06 4.8e-06
17 Brain mRNA stability Rap1gap2 0.14 0.06 6.3e-15 0.12 0.16 0.16 0.16 1.7e-11 8.9e-15 2.3e-14 1.6e-14
18 Adipose isoform ratio XM_008767832.4 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 5.6e-03 2.3e-03 7.9e-03 5.9e-03
19 Brain alternative TSS XM_063269050.1 0.04 0.03 4.1e-04 0.03 0.04 0.03 0.02 6.6e-04 2.4e-04 1.7e-03 4.9e-03
20 PL isoform ratio XM_017597290.3 0.04 0.04 2.8e-04 0.04 0.03 0.03 0.03 9.7e-05 2.6e-04 2.9e-04 3.5e-04
21 PL intron excision ratio chr10_59855162_59930611 0.02 0.02 1.9e-03 0.02 0.02 0.01 0.01 5.4e-03 2.7e-03 7.3e-03 7.1e-03
22 Brain intron excision ratio chr10_59855162_59892814 0.04 0.03 9.3e-04 0.04 0.03 0.02 0.03 2.9e-04 7.7e-04 2.2e-03 4.4e-04
23 Liver gene expression Rap1gap2 0.16 0.1 4.5e-13 0.1 0.1 0.1 0.1 1.2e-11 1.6e-11 9.7e-12 1.3e-11
24 Brain isoform ratio XM_017597290.3 0.05 0.04 1.9e-04 0.05 0.04 0.03 0.03 3.6e-05 1.8e-04 1.8e-03 6.3e-04
25 IC isoform ratio XM_017597290.3 0.08 0.06 2.5e-03 0.07 0.07 0.07 0.06 5.5e-04 9.2e-04 4.6e-04 1.0e-03
26 IC alternative TSS XM_063269050.1 0.09 0.06 1.6e-03 0.07 0.07 0.06 0.06 8.2e-04 9.0e-04 1.6e-03 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density3.25.99.4-2.8-3.0-3.02.9-2.9-3.02.73.1-3.02.82.82.8-1.9-2.82.92.02.3-2.11.8-1.3-1.7-1.4-1.7-1.4-1.5-1.4
Area under the delay curve0.20.41.70.60.60.6-0.70.50.7-0.4-0.80.6-0.6-0.6-0.60.41.3-0.9-0.2-0.60.5-0.40.20.40.20.70.30.10.5
BMI with tail1.34.67.1-2.1-2.7-2.72.4-2.3-2.42.42.5-2.12.32.32.3-2.1-2.12.42.22.2-2.11.9-1.7-1.9-1.8-1.5-1.5-1.4-1.3
BMI without tail0.31.43.6-1.5-1.8-1.81.6-1.4-1.91.61.7-1.31.51.51.5-0.4-1.11.40.60.7-0.50.20.2-0.10.20.20.50.40.7
Body weight0.41.74.3-1.3-1.5-1.51.5-1.4-2.11.21.5-1.31.51.51.50.4-0.81.2-0.30.00.2-0.81.51.01.41.21.61.11.8
Weight adjusted by age0.92.53.8-1.7-1.9-1.91.6-1.4-1.51.81.8-1.71.61.61.6-1.4-0.71.41.91.7-1.71.6-1.7-1.6-1.7-1.3-1.6-1.1-1.3
Bone surface3.77.210.0-2.8-3.2-3.23.1-3.0-3.03.13.2-2.92.82.82.8-2.6-3.03.12.52.7-2.62.4-2.0-2.3-2.1-2.1-2.1-1.8-2.0
Bone volume3.87.510.2-2.8-3.2-3.23.1-3.1-3.13.13.2-3.02.82.82.8-2.7-3.03.22.62.8-2.72.4-2.1-2.3-2.1-2.1-2.0-1.9-2.0
Breakpoint value in progressive ratio session0.30.61.6-0.9-1.0-1.01.1-1.1-1.31.11.1-1.01.21.21.2-0.3-0.60.80.40.5-0.40.20.1-0.10.10.00.00.00.4
Number of licking bursts0.10.30.90.20.60.6-0.70.80.8-0.7-0.60.2-0.5-0.5-0.50.90.9-0.7-0.5-0.60.5-0.40.20.40.40.20.30.60.3
Context. condit. distance diff. score1.01.22.6-1.5-1.3-1.31.3-1.4-1.41.11.5-1.61.51.51.5-0.4-1.01.20.80.9-0.80.7-0.2-0.6-0.5-0.6-0.4-0.6-0.5
Locomotion velocity, session 11.01.13.2-1.2-1.3-1.31.5-1.5-1.81.31.3-1.21.41.41.4-0.7-1.51.40.40.8-0.60.20.2-0.10.2-0.40.1-0.20.2
Locomotion distance, session 10.40.51.1-0.7-0.8-0.80.8-0.8-0.90.60.8-0.70.80.80.8-0.8-1.01.00.50.7-0.70.6-0.2-0.5-0.6-0.8-0.6-0.3-0.5
Locomotion velocity, session 20.40.51.1-0.8-0.8-0.80.9-0.9-1.00.70.8-0.80.80.80.8-0.8-1.00.90.40.7-0.60.4-0.2-0.4-0.3-0.6-0.3-0.5-0.3
Locomotion distance, session 21.52.03.0-1.6-1.7-1.71.6-1.7-1.61.51.7-1.61.71.71.7-1.3-1.61.71.21.4-1.31.2-0.7-1.1-1.1-1.3-1.0-1.0-0.8
Locomotion velocity, session 35.86.69.43.02.82.8-2.82.92.7-2.8-2.93.1-2.9-2.9-2.92.22.6-2.7-2.6-2.62.5-2.42.22.31.82.11.72.21.8
Locomotion distance, session 30.10.10.40.3-0.1-0.10.1-0.1-0.00.2-0.00.20.00.00.0-0.6-0.10.20.20.3-0.30.3-0.2-0.3-0.7-0.3-0.60.1-0.5
Stereotopy head waving bouts, day 30.40.51.90.30.20.2-0.60.60.4-0.7-0.30.5-0.5-0.5-0.51.40.5-0.5-1.0-0.80.9-0.91.10.90.90.60.80.81.0
Stereotopy head waving duration, day 30.20.20.80.20.30.3-0.60.70.6-0.8-0.30.4-0.5-0.5-0.50.90.4-0.4-0.5-0.40.4-0.30.30.30.2-0.10.20.20.2
Locomotion velocity, session 71.71.83.0-1.0-1.4-1.41.5-1.5-1.41.71.4-1.01.21.21.2-1.7-1.31.41.61.5-1.51.4-1.4-1.4-1.3-1.1-1.0-1.3-0.9
Locomotion distance, session 73.34.36.1-2.3-2.5-2.52.2-2.3-2.12.42.2-1.92.12.12.1-1.8-1.72.12.32.1-2.12.0-1.9-2.0-2.0-1.6-1.5-1.8-1.4
Stereotopy head waving bouts, day 70.30.41.0-0.7-1.0-1.00.7-0.7-0.80.51.0-0.80.80.80.80.2-0.70.8-0.00.3-0.20.00.3-0.00.1-0.4-0.00.1-0.0
Stereotopy head waving duration, day 70.70.81.7-0.9-1.3-1.31.0-1.1-1.10.91.3-1.11.11.11.1-0.5-1.21.10.40.8-0.70.5-0.2-0.5-0.3-0.8-0.5-0.3-0.5
Locomotion velocity, session 80.50.50.8-0.9-0.9-0.90.7-0.8-0.70.50.9-0.90.90.90.9-0.5-0.80.80.40.7-0.60.5-0.3-0.5-0.7-0.7-0.9-0.6-0.9
Locomotion distance, session 81.62.44.8-2.1-2.1-2.11.9-2.0-2.01.62.2-2.02.12.12.1-0.5-1.41.91.01.2-1.10.8-0.2-0.7-0.7-0.8-0.4-0.7-0.4
Degree of sensitization distance1.21.33.1-1.8-1.6-1.61.4-1.4-1.41.41.4-1.31.31.31.3-0.4-1.01.21.21.0-0.90.9-0.8-0.8-0.5-0.5-0.2-1.1-0.2
Degree of sensitization stereotypy0.60.61.3-1.0-1.1-1.11.0-1.1-1.10.91.1-1.11.01.01.0-0.2-1.01.00.20.6-0.50.20.0-0.2-0.0-0.5-0.2-0.2-0.2
Conditioned locomotion0.40.50.90.90.90.9-0.90.91.0-0.9-1.00.8-0.7-0.7-0.70.70.7-0.7-0.8-0.60.6-0.50.40.40.30.00.20.50.2
Cocaine response after cond. corrected0.10.10.7-0.2-0.1-0.1-0.10.0-0.0-0.20.1-0.1-0.0-0.0-0.00.80.1-0.2-0.5-0.40.5-0.50.60.60.60.40.60.30.5
Cocaine response after cond. not corrected0.10.10.3-0.4-0.3-0.30.3-0.3-0.40.20.3-0.30.20.20.20.4-0.20.1-0.3-0.10.2-0.30.30.30.50.20.40.20.4
Cocaine response before conditioning0.70.91.8-0.6-0.9-0.91.2-1.2-1.21.31.0-0.90.90.90.9-1.3-1.11.10.91.0-1.00.8-0.9-0.8-0.5-0.7-0.6-0.6-0.5
Saline control response1.01.32.1-1.2-1.2-1.21.2-1.1-1.01.21.0-1.00.90.90.9-1.4-1.11.11.31.3-1.31.3-1.3-1.3-1.3-1.1-1.1-1.2-1.1
Bone: connectivity density5.28.312.7-3.1-3.5-3.53.4-3.4-3.53.23.6-3.33.23.23.2-2.3-3.53.52.42.8-2.62.3-1.7-2.2-1.8-2.2-1.8-1.8-1.9
Bone: cortical apparent density0.10.10.50.00.20.2-0.30.30.4-0.3-0.30.1-0.2-0.2-0.2-0.10.3-0.20.30.2-0.20.4-0.5-0.4-0.7-0.5-0.4-0.5-0.4
Bone: cortical area1.01.63.01.61.41.4-1.41.61.5-1.2-1.61.7-1.7-1.7-1.70.71.6-1.5-0.7-1.11.0-0.80.40.80.41.30.70.80.8
Bone: cortical porosity0.20.20.4-0.7-0.6-0.60.5-0.5-0.60.50.7-0.60.60.60.6-0.1-0.40.60.30.3-0.30.2-0.0-0.2-0.2-0.1-0.2-0.2-0.1
Bone: cortical porosity0.00.00.1-0.2-0.2-0.20.1-0.1-0.10.10.3-0.20.10.10.10.10.10.10.0-0.00.0-0.00.10.10.10.20.1-0.00.2
Bone: cortical thickness5.99.812.83.53.33.3-3.43.53.4-3.3-3.43.6-3.6-3.6-3.62.93.4-3.4-2.8-3.23.0-2.82.32.72.23.12.52.52.4
Bone: cortical thickness2.22.73.81.51.31.3-1.61.61.4-1.6-1.51.7-1.6-1.6-1.62.01.6-1.6-1.6-1.71.7-1.71.71.71.51.91.81.51.9
Bone: cortical tissue density0.10.10.4-0.10.10.1-0.10.20.3-0.2-0.1-0.0-0.0-0.0-0.0-0.10.2-0.10.30.2-0.30.4-0.5-0.4-0.6-0.6-0.4-0.5-0.4
Condit. Reinf. active minus inactive responses0.60.71.01.00.90.9-0.70.70.6-0.6-0.80.9-1.0-1.0-1.00.20.7-0.6-0.8-0.80.8-0.80.70.81.00.80.90.80.9
Condit. Reinf. active-inactive response ratio4.44.85.82.42.22.2-2.02.01.8-1.9-2.12.3-2.4-2.4-2.41.72.1-2.0-2.2-2.32.3-2.32.02.22.32.42.32.02.4
Condit. Reinf. active responses0.20.30.7-0.5-0.5-0.50.6-0.6-0.60.60.5-0.50.50.50.5-0.9-0.60.70.60.6-0.60.5-0.4-0.5-0.3-0.5-0.3-0.4-0.2
Condit. Reinf. inactive responses5.67.28.8-2.8-2.6-2.62.5-2.5-2.22.52.5-2.82.82.82.8-2.6-2.52.62.92.9-2.92.9-2.6-2.9-2.7-3.0-2.6-2.6-2.7
Incentive salience index mean0.60.81.51.10.90.9-0.60.70.5-0.6-0.71.0-1.0-1.0-1.00.30.5-0.6-1.0-0.90.9-1.01.01.01.21.01.11.01.2
Condit. Reinf. lever presses0.20.41.50.40.10.10.1-0.1-0.30.00.10.3-0.2-0.2-0.20.2-0.20.1-0.7-0.50.6-0.81.00.81.20.91.10.91.1
Condit. Reinf. active minus inactive responses1.01.62.8-1.3-1.3-1.31.3-1.4-1.31.51.3-1.31.21.21.2-1.7-1.01.11.41.3-1.31.2-1.2-1.2-1.2-0.9-1.0-1.2-0.9
Condit. Reinf. active-inactive response ratio0.00.00.2-0.10.00.00.0-0.1-0.10.10.0-0.10.00.00.0-0.00.2-0.2-0.1-0.20.2-0.20.20.20.10.40.3-0.00.3
Condit. Reinf. active responses2.94.27.7-1.9-1.9-1.92.1-2.1-1.92.31.9-1.91.81.81.8-2.8-1.71.92.42.2-2.32.2-2.4-2.2-2.1-1.8-1.9-2.0-1.9
Condit. Reinf. inactive responses4.87.211.6-2.3-2.4-2.42.5-2.4-2.22.72.3-2.22.12.12.1-3.4-2.42.63.13.0-3.13.1-3.3-3.1-3.0-2.9-2.9-2.6-2.8
Condit. Reinf. lever presses0.60.82.4-0.2-0.2-0.20.4-0.5-0.10.60.4-0.40.40.40.4-1.4-0.40.41.10.9-1.01.2-1.6-1.3-1.3-1.2-1.4-1.4-1.4
Condit. Reinf. lever reinforcers received3.24.58.4-1.9-1.9-1.92.1-2.1-1.82.31.9-1.91.81.81.8-2.9-1.71.92.62.3-2.42.4-2.5-2.3-2.3-1.9-2.0-2.2-2.0
Conditioned reinforcement - actives0.83.25.3-2.0-1.9-1.92.0-1.9-1.92.01.6-1.71.51.51.5-2.3-2.01.82.01.9-1.91.8-1.8-1.8-1.7-1.7-1.5-1.6-1.3
Conditioned reinforcement - inactives0.41.22.0-1.4-1.1-1.11.2-1.0-1.11.31.0-1.11.21.21.2-1.3-0.51.01.31.1-1.11.1-1.2-1.1-1.1-0.9-0.7-0.8-0.5
Conditioned locomotion0.10.10.70.20.00.0-0.20.40.5-0.1-0.20.3-0.4-0.4-0.4-0.4-0.1-0.10.40.2-0.20.5-0.8-0.5-0.7-0.2-0.5-0.3-0.3
Patch foraging indifference point 0 sec0.10.20.5-0.1-0.4-0.40.5-0.6-0.50.50.6-0.30.40.40.4-0.4-0.70.60.30.4-0.40.3-0.4-0.3-0.3-0.5-0.4-0.1-0.5
Patch foraging indifference point AUC0.20.41.2-0.6-0.4-0.40.2-0.10.00.20.2-0.40.30.30.3-0.70.10.20.80.6-0.70.8-0.9-0.8-1.1-0.7-0.9-0.8-1.1
Delay disc. indifference point, 0s delay0.40.40.8-0.3-0.5-0.50.7-0.8-0.70.90.5-0.50.60.60.6-0.9-0.70.60.70.7-0.70.6-0.6-0.6-0.4-0.4-0.7-0.6-0.7
Delay disc. indifference point, 16s delay0.10.21.80.20.10.1-0.40.30.6-0.1-0.30.2-0.3-0.3-0.30.21.3-0.70.3-0.20.10.0-0.4-0.0-0.40.5-0.2-0.50.4
Delay disc. indifference point, 2s delay0.30.41.60.50.80.8-0.70.60.7-0.6-0.60.5-0.5-0.5-0.50.61.2-0.8-0.4-0.60.6-0.50.40.50.50.60.4-0.10.5
Delay disc. indifference point, 24s delay0.00.10.50.1-0.0-0.0-0.0-0.00.10.20.0-0.20.10.10.1-0.10.7-0.20.40.1-0.10.2-0.4-0.2-0.30.2-0.3-0.10.2
Delay disc. indifference point, 4s delay0.20.21.30.10.30.3-0.40.30.4-0.3-0.30.3-0.3-0.3-0.30.51.1-0.6-0.3-0.50.5-0.50.40.60.40.80.50.30.6
Delay disc. indifference point, 8s delay0.20.30.90.50.60.6-0.60.50.6-0.4-0.80.6-0.5-0.5-0.50.51.0-0.7-0.4-0.60.5-0.50.40.50.40.70.50.30.5
Indifference point function ln k0.10.31.4-0.5-0.6-0.60.8-0.9-1.00.80.6-0.40.60.60.6-0.2-1.20.80.10.5-0.40.10.1-0.10.1-0.3-0.10.1-0.0
Indifference point function log k0.10.31.4-0.5-0.6-0.60.8-0.9-1.00.80.6-0.40.60.60.6-0.2-1.20.80.10.5-0.40.10.1-0.10.1-0.3-0.10.1-0.0
Patch foraging total patch changes 0 sec0.10.30.8-0.2-0.5-0.50.6-0.7-0.60.60.6-0.40.50.50.5-0.5-0.90.70.40.6-0.50.4-0.5-0.5-0.4-0.6-0.6-0.3-0.7
Patch foraging total patch changes 12 sec0.70.91.21.11.01.0-1.01.00.9-1.0-0.91.0-1.1-1.1-1.10.71.1-0.9-1.0-1.00.9-0.90.90.90.90.80.80.90.5
Patch foraging total patch changes 18 sec0.10.30.70.40.50.5-0.60.60.6-0.6-0.30.3-0.3-0.3-0.30.60.8-0.6-0.4-0.60.5-0.50.40.50.30.80.20.40.2
Patch foraging total patch changes 24 sec0.10.30.90.90.70.7-0.70.70.8-0.6-0.60.6-0.6-0.6-0.60.30.9-0.7-0.4-0.50.5-0.40.20.30.30.50.20.40.2
Patch foraging total patch changes 6 sec0.10.21.10.10.00.0-0.0-0.00.20.10.1-0.1-0.0-0.0-0.0-0.6-0.20.20.40.4-0.40.6-0.8-0.6-0.7-0.6-0.8-0.4-1.0
Patch foraging time to switch 0 sec0.93.45.41.81.71.7-1.81.71.6-1.9-1.41.3-1.3-1.3-1.32.31.8-1.8-2.1-2.12.1-2.12.02.12.22.12.21.42.2
Patch foraging water rate 0 sec0.31.12.9-0.7-0.6-0.60.8-0.7-0.60.90.4-0.30.30.30.3-1.7-1.00.91.21.2-1.31.3-1.4-1.3-1.5-1.5-1.4-0.9-1.5
Patch foraging water rate 12 sec0.00.10.5-0.5-0.2-0.20.5-0.5-0.50.60.1-0.10.30.30.3-0.7-0.40.30.50.4-0.40.3-0.2-0.3-0.3-0.1-0.1-0.1-0.0
Patch foraging water rate 18 sec1.84.06.1-2.2-2.1-2.12.4-2.3-2.42.41.8-1.81.81.81.8-2.5-2.42.32.02.2-2.11.9-1.6-1.8-1.5-2.1-1.4-1.3-1.5
Patch foraging water rate 24 sec0.30.42.0-0.1-0.2-0.20.6-0.4-0.50.60.1-0.0-0.0-0.0-0.0-1.4-0.80.70.70.8-0.80.8-0.8-0.8-0.7-1.0-0.5-0.3-0.7
Patch foraging water rate 6 sec0.10.10.20.20.30.3-0.20.30.3-0.1-0.30.4-0.4-0.4-0.4-0.30.1-0.20.20.1-0.20.2-0.4-0.3-0.3-0.3-0.1-0.0-0.2
Seeking ratio, delayed vs. immediate footshock0.10.20.90.20.20.2-0.60.40.8-0.5-0.30.3-0.4-0.4-0.40.10.9-0.50.1-0.10.00.2-0.3-0.2-0.7-0.2-0.8-0.3-0.7
Distance traveled before self-admin0.71.65.81.31.51.5-1.71.31.9-1.4-1.61.5-1.3-1.3-1.31.22.4-1.7-0.8-1.21.1-0.80.30.70.40.90.2-0.20.6
Distance traveled after self-admin0.10.10.70.10.20.2-0.40.30.4-0.1-0.50.5-0.5-0.5-0.50.20.9-0.40.0-0.30.2-0.1-0.20.1-0.10.3-0.1-0.10.5
Extensor digitorum longus weight5.220.726.4-4.9-5.1-5.14.9-4.8-4.84.75.0-4.74.74.74.7-4.6-5.15.14.24.7-4.64.2-3.6-4.2-3.7-4.4-3.7-3.5-3.8
Bone: elastic displacement0.20.20.60.60.60.6-0.60.70.8-0.7-0.60.5-0.7-0.7-0.70.00.5-0.5-0.1-0.20.20.0-0.0-0.1-0.10.0-0.10.1-0.3
Bone: elastic work5.87.611.23.32.92.9-3.03.23.1-3.0-2.93.3-3.3-3.3-3.32.32.8-2.9-2.5-2.72.6-2.32.02.22.02.42.02.61.8
Bone: endosteal estimation0.41.02.1-0.9-1.0-1.01.0-0.8-0.91.10.8-0.90.80.80.8-1.4-0.60.91.21.1-1.11.1-1.4-1.1-1.1-1.1-1.1-1.0-0.9
Bone: endosteal perimeter2.15.08.6-2.1-2.1-2.12.2-2.1-1.92.41.9-2.01.91.91.9-2.9-1.82.12.72.5-2.52.5-2.5-2.5-2.4-2.2-2.4-2.1-2.2
Epididymis fat weight4.321.636.7-5.9-5.6-5.65.7-5.7-6.15.35.8-5.86.06.06.0-3.3-4.85.23.94.2-3.93.2-2.2-2.9-2.2-2.7-2.1-2.7-1.6
Delta time in closed arm before/after self-admin0.20.20.7-0.10.30.3-0.30.20.4-0.20.1-0.30.30.30.30.10.8-0.30.20.1-0.20.3-0.4-0.3-0.4-0.6-0.8-0.3-0.8
Delta time in open arm before/after self-admin0.40.51.1-0.6-1.0-1.00.9-0.9-1.00.91.0-0.80.80.80.8-0.6-1.00.90.60.6-0.60.5-0.3-0.5-0.4-0.1-0.1-0.4-0.2
Diff in mean of infusions in LGA sessions0.20.41.1-0.8-0.7-0.70.9-0.8-1.10.70.9-0.70.80.80.8-0.3-0.90.70.10.3-0.2-0.00.40.10.3-0.1-0.00.40.0
Delay discount exponential model param0.20.31.6-0.6-0.6-0.60.6-0.5-0.70.40.7-0.60.60.60.6-0.4-1.30.80.30.6-0.50.4-0.2-0.4-0.2-0.7-0.3-0.2-0.5
Extinction: sum of active levers before priming3.24.96.9-2.4-2.4-2.42.5-2.3-2.42.42.6-2.42.62.62.6-2.2-2.02.22.32.3-2.22.0-1.7-2.0-1.8-1.9-1.8-1.5-1.4
Active lever presses in extinction session 63.23.24.5-2.0-2.1-2.12.1-2.1-2.12.11.9-1.82.02.02.0-1.7-1.91.91.71.8-1.71.5-1.2-1.4-1.3-1.5-1.4-1.2-1.3
Bone: final force1.72.84.72.21.41.4-1.51.61.4-1.3-1.42.0-1.7-1.7-1.71.61.4-1.4-1.7-1.71.8-1.81.51.71.72.01.62.01.7
Bone: final moment1.42.34.22.11.31.3-1.41.51.3-1.2-1.21.9-1.7-1.7-1.71.41.2-1.3-1.6-1.61.6-1.61.21.51.41.81.41.81.4
Food consumed during 24 hour testing period0.20.40.9-0.6-0.7-0.70.7-0.8-0.70.71.0-0.80.80.80.8-0.4-0.60.70.40.6-0.50.4-0.1-0.4-0.3-0.3-0.5-0.4-0.4
Glucose2.13.46.12.32.42.4-2.32.32.5-2.1-2.32.1-2.1-2.1-2.11.12.3-2.3-1.3-1.71.5-1.20.81.10.81.40.60.90.7
Heart weight0.30.51.4-0.7-1.0-1.00.8-0.8-1.00.61.2-0.81.01.01.00.4-0.90.9-0.20.2-0.0-0.20.60.30.50.30.60.60.3
Delay discount hyperbolic model param0.40.62.0-0.7-0.8-0.80.8-0.7-0.80.60.9-0.80.80.80.8-0.6-1.41.00.50.8-0.70.7-0.4-0.6-0.5-0.9-0.6-0.4-0.7
Intermittent access intake day 1-15 change0.21.03.0-0.2-0.1-0.10.2-0.40.10.40.4-0.70.60.60.6-1.4-0.10.31.30.9-1.11.4-1.7-1.4-1.6-1.1-1.7-1.7-1.4
Intermittent access intake escalation0.21.23.5-0.2-0.2-0.20.3-0.50.10.60.5-0.70.50.50.5-1.6-0.10.41.51.1-1.21.5-1.9-1.6-1.7-1.2-1.9-1.7-1.5
Intermittent access intake escalation 20.30.51.90.30.40.4-0.20.00.6-0.0-0.2-0.20.00.00.0-0.90.1-0.10.80.5-0.71.0-1.3-1.0-1.1-0.9-1.4-1.3-1.4
Intermitt. access day 1 inactive lever presses0.10.72.10.80.70.7-0.90.91.2-0.5-1.31.4-1.4-1.4-1.4-0.60.7-0.80.1-0.20.00.2-0.7-0.3-0.6-0.2-0.5-0.2-0.7
Intermitt. access day 15 inactive lever presses0.10.41.4-0.3-0.2-0.2-0.20.10.50.2-0.1-0.20.20.20.2-0.30.9-0.40.80.4-0.50.7-1.1-0.8-1.1-0.8-1.2-0.8-1.0
Intermitt. access escalation Index0.31.02.70.40.40.4-0.40.50.1-0.7-0.10.2-0.1-0.1-0.11.60.4-0.4-1.3-1.11.2-1.31.61.41.61.41.61.11.6
Intermittent access day 1 total infusions0.10.30.6-0.8-0.8-0.80.6-0.6-0.50.70.5-0.60.50.50.5-0.60.20.30.80.5-0.60.5-0.7-0.5-0.6-0.3-0.5-0.8-0.0
Intermittent access day 15 total infusions0.92.34.4-1.1-1.2-1.21.2-1.3-0.91.41.3-1.41.21.21.2-1.9-0.61.11.91.6-1.71.8-2.1-1.8-2.0-1.4-2.1-1.9-1.4
Intermittent access terminal intake (last 3 days)1.32.33.7-1.4-1.4-1.41.4-1.6-1.21.51.3-1.51.41.41.4-1.8-1.21.31.71.6-1.61.6-1.7-1.6-1.6-1.4-1.8-1.9-1.4
Intermittent access total infusions1.41.73.3-1.2-1.2-1.21.1-1.3-0.91.41.2-1.21.11.11.1-1.5-0.30.91.61.3-1.41.4-1.7-1.4-1.5-1.1-1.6-1.8-1.0
Intermittent access day 1 locomotion0.00.10.4-0.1-0.3-0.30.1-0.0-0.10.4-0.10.4-0.3-0.3-0.3-0.30.6-0.20.2-0.00.0-0.1-0.20.10.00.30.20.10.6
Intermittent access day 15 total locomotion0.10.31.1-0.2-0.3-0.30.2-0.10.00.40.1-0.10.00.00.0-1.00.30.10.90.5-0.60.7-1.1-0.7-0.9-0.4-0.8-0.8-0.3
Intermittent access total locomotion0.50.61.6-0.5-0.7-0.70.6-0.6-0.51.00.5-0.50.50.50.5-1.30.20.41.10.8-0.90.9-1.2-0.9-1.0-0.6-0.9-0.9-0.4
Intermittent access standard deviation0.73.67.9-1.4-1.4-1.41.3-1.4-0.81.61.2-1.41.21.21.2-2.5-0.91.22.42.1-2.22.4-2.8-2.5-2.6-2.2-2.7-2.2-2.5
Left kidney weight1.411.115.53.23.03.0-3.33.43.0-3.4-2.93.1-3.0-3.0-3.03.93.7-3.3-3.4-3.63.6-3.53.33.53.33.83.43.03.6
Right kidney weight1.410.014.52.72.62.6-2.93.02.5-3.0-2.62.8-2.7-2.7-2.73.83.5-3.0-3.4-3.53.5-3.53.53.53.53.83.73.03.8
Cocaine induced anxiety0.00.10.30.10.30.3-0.30.20.4-0.4-0.40.3-0.6-0.6-0.6-0.2-0.1-0.2-0.1-0.10.00.1-0.1-0.1-0.1-0.2-0.1-0.3-0.5
Post-drug Anxiety0.30.31.00.10.40.4-0.20.1-0.0-0.5-0.40.4-0.5-0.5-0.50.5-0.5-0.1-0.9-0.60.6-0.81.00.81.00.41.00.10.4
Baseline Anxiety0.10.20.6-0.3-0.3-0.30.5-0.5-0.70.30.5-0.40.60.60.60.4-0.70.4-0.3-0.10.2-0.40.70.50.70.30.70.00.6
Tail length0.63.09.80.30.40.4-0.20.2-0.4-0.5-0.30.3-0.2-0.2-0.22.20.6-0.5-2.2-1.72.0-2.53.02.63.12.52.82.42.8
Length with tail1.15.114.30.81.11.1-0.80.70.1-1.1-0.90.8-0.7-0.7-0.72.91.3-1.1-2.8-2.42.6-3.13.73.23.83.13.52.93.6
Length without tail0.10.62.3-0.20.10.10.3-0.4-0.70.10.1-0.20.30.30.30.70.00.0-0.9-0.60.8-1.11.51.21.51.11.40.91.4
Times rat made contact with spout2.22.53.71.81.51.5-1.41.51.3-1.3-1.61.9-1.9-1.9-1.91.41.3-1.5-1.5-1.61.6-1.61.51.61.51.81.61.41.6
Lifetime Intake1.11.42.4-1.1-1.2-1.21.1-1.2-0.91.31.0-1.10.90.90.9-1.5-0.30.81.51.2-1.31.3-1.5-1.3-1.4-1.0-1.5-1.5-0.9
Liver weight, left1.11.98.2-0.9-0.7-0.70.8-0.8-1.40.40.7-0.60.80.80.81.5-0.00.4-1.1-0.81.1-1.62.31.82.31.82.51.42.9
Liver weight, right1.01.73.6-1.5-1.5-1.51.4-1.5-1.91.21.4-1.21.61.61.60.9-0.60.9-0.4-0.10.3-0.91.51.01.61.01.70.71.8
Locomotor activity0.40.61.3-1.1-1.0-1.00.8-0.8-0.70.90.8-0.91.01.01.0-0.6-0.20.61.10.7-0.70.8-0.9-0.7-0.7-0.3-0.5-0.9-0.2
Locomotor testing distance0.10.20.5-0.6-0.5-0.50.3-0.3-0.30.30.4-0.50.50.50.5-0.1-0.20.20.50.3-0.30.4-0.5-0.4-0.3-0.2-0.3-0.7-0.1
Locomotor testing rearing0.51.83.4-1.4-1.2-1.21.2-1.2-1.01.11.2-1.41.21.21.2-1.2-1.11.11.61.4-1.51.6-1.7-1.6-1.5-1.3-1.5-1.8-1.3
Locomotion in novel chamber0.71.04.50.40.30.3-0.3-0.00.7-0.1-0.20.2-0.3-0.3-0.3-1.00.3-0.21.00.7-0.91.2-1.6-1.3-1.6-1.3-1.9-2.1-1.7
Locomotion in novel chamber post-restriction0.20.61.4-0.4-0.7-0.70.6-0.8-0.50.60.9-0.80.90.90.9-0.6-0.90.70.60.8-0.80.8-0.9-0.8-0.8-1.0-0.9-1.1-1.2
Fecal boli incidents, locomotor time 10.20.40.80.70.60.6-0.60.50.5-0.7-0.50.6-0.7-0.7-0.70.70.1-0.5-0.9-0.70.7-0.70.80.70.90.40.70.50.3
Change in fecal boli incidents, locomotor task0.60.70.80.80.80.8-0.80.90.8-0.9-0.70.7-0.8-0.8-0.80.90.8-0.7-0.8-0.90.9-0.80.80.80.80.90.80.80.7
Time >=10cm from walls, locomotor time 10.10.10.5-0.1-0.4-0.40.3-0.2-0.30.40.5-0.1-0.0-0.0-0.0-0.5-0.70.50.20.4-0.40.3-0.4-0.4-0.4-0.4-0.30.0-0.4
Bouts of movement, locomotor time 10.00.00.20.1-0.1-0.10.2-0.3-0.30.20.20.00.10.10.1-0.2-0.40.2-0.10.1-0.1-0.00.20.00.4-0.2-0.10.2-0.1
Total resting periods, locomotor time 10.00.10.2-0.1-0.2-0.20.3-0.3-0.30.30.3-0.10.20.20.2-0.3-0.40.30.10.2-0.20.20.0-0.20.1-0.4-0.30.1-0.4
Rest time, locomotor task time 10.10.20.40.50.60.6-0.50.40.6-0.5-0.60.4-0.6-0.6-0.6-0.00.5-0.4-0.3-0.20.2-0.10.10.00.2-0.2-0.20.0-0.2
Distance moved, locomotor task time 10.10.30.5-0.6-0.6-0.60.6-0.5-0.50.50.7-0.60.60.60.6-0.5-0.30.50.60.5-0.50.5-0.4-0.5-0.5-0.3-0.4-0.3-0.2
Vertical activity count, locomotor time 10.10.71.3-0.8-0.9-0.91.0-0.9-1.00.91.1-0.80.80.80.8-0.8-1.11.00.80.9-0.90.8-0.7-0.8-0.8-0.8-0.6-0.7-0.7
Time >=10cm from walls, locomotor time 20.10.41.00.90.30.3-0.60.60.6-0.3-0.41.0-1.0-1.0-1.00.40.8-0.5-0.4-0.50.5-0.50.20.40.30.70.60.70.4
Bouts of movement, locomotor time 20.00.00.1-0.00.00.00.1-0.2-0.10.2-0.20.1-0.1-0.1-0.1-0.20.1-0.10.10.0-0.0-0.0-0.00.00.00.2-0.1-0.20.2
Total resting periods, locomotor time 20.00.10.3-0.3-0.3-0.30.4-0.5-0.40.50.1-0.20.10.10.1-0.5-0.30.20.40.3-0.30.2-0.3-0.2-0.1-0.0-0.3-0.20.0
Rest time, locomotor task time 20.20.40.9-1.0-0.5-0.50.5-0.5-0.40.60.4-0.90.60.60.6-0.7-0.10.40.90.6-0.70.8-0.8-0.7-0.5-0.6-0.9-0.8-0.5
Distance moved, locomotor task time 20.10.10.50.10.10.1-0.00.00.1-0.00.00.0-0.0-0.0-0.0-0.5-0.30.10.20.3-0.30.4-0.3-0.4-0.4-0.5-0.2-0.2-0.7
Vertical activity count, locomotor time 20.20.61.00.90.80.8-0.70.70.7-0.9-0.60.8-0.8-0.8-0.80.80.1-0.6-1.0-0.70.8-0.80.90.70.70.40.90.60.2
Light reinforcement 10.00.10.4-0.1-0.0-0.00.2-0.3-0.10.20.3-0.50.40.40.4-0.3-0.20.20.30.3-0.30.3-0.3-0.3-0.1-0.3-0.1-0.7-0.2
Light reinforcement 21.63.64.51.81.91.9-2.02.02.0-2.0-2.12.0-2.0-2.0-2.02.12.1-2.0-1.8-2.02.0-1.81.51.81.81.81.81.41.8
Bone: marrow area0.40.91.9-0.9-0.9-0.90.9-0.8-0.81.10.8-0.80.80.80.8-1.4-0.60.91.11.1-1.11.1-1.3-1.1-1.1-1.0-1.0-0.9-0.8
Bone: maximum diameter0.51.02.7-0.5-0.7-0.70.7-0.6-0.51.00.6-0.50.40.40.4-1.7-0.50.71.41.1-1.21.3-1.6-1.3-1.4-1.0-1.3-0.9-1.2
Bone: maximum force1.42.74.12.01.41.4-1.61.71.5-1.4-1.41.9-1.8-1.8-1.81.61.6-1.5-1.7-1.71.7-1.71.41.61.51.91.51.81.6
Bone: maximum moment1.12.23.61.91.31.3-1.51.61.4-1.3-1.31.8-1.7-1.7-1.71.41.4-1.4-1.4-1.51.5-1.41.11.41.21.61.21.61.3
Mean time between licks in bursts0.10.31.10.00.10.1-0.10.1-0.1-0.2-0.20.2-0.1-0.1-0.10.70.1-0.2-0.7-0.60.6-0.81.00.80.90.61.00.61.0
Mean num. licks in bursts0.20.51.21.00.50.5-0.30.30.2-0.2-0.51.1-0.8-0.8-0.80.1-0.0-0.4-0.6-0.60.6-0.70.80.70.71.10.80.60.8
Cd content in liver3.03.45.1-2.3-1.7-1.71.6-1.6-1.41.71.6-2.01.81.81.8-1.8-1.21.52.21.9-2.02.1-2.1-2.0-2.2-1.8-2.0-2.1-1.7
Co content in liver0.00.00.30.2-0.0-0.00.00.10.10.3-0.30.4-0.2-0.2-0.2-0.50.0-0.20.30.1-0.10.1-0.4-0.1-0.10.2-0.0-0.00.2
Cu content in liver0.70.81.51.21.21.2-1.01.21.1-0.8-1.11.1-0.9-0.9-0.90.31.2-1.1-0.6-0.80.7-0.60.30.60.50.70.51.10.7
Fe content in liver0.30.41.10.10.20.2-0.20.30.0-0.4-0.20.2-0.0-0.0-0.00.80.2-0.2-0.8-0.70.8-0.91.10.91.00.81.01.01.0
K content in liver1.21.24.11.30.80.8-0.70.80.4-0.6-0.81.1-0.8-0.8-0.80.60.6-0.8-1.2-1.11.1-1.31.31.31.61.41.42.01.4
Mg content in liver0.30.31.4-0.2-0.4-0.40.6-0.4-0.50.80.4-0.20.30.30.3-1.2-0.70.50.70.7-0.70.7-0.7-0.7-0.5-0.6-0.6-0.0-0.6
Mn content in liver0.50.51.1-0.4-0.5-0.50.6-0.5-0.50.50.7-0.81.01.01.0-0.6-0.90.70.60.8-0.80.7-0.6-0.8-0.6-1.0-0.8-0.2-1.0
Na content in liver2.52.84.21.91.81.8-1.71.81.7-1.5-1.92.0-1.9-1.9-1.91.41.8-1.9-1.4-1.61.6-1.51.21.51.31.71.41.41.5
Rb content in liver5.36.28.2-2.6-2.7-2.72.6-2.6-2.52.72.6-2.62.92.92.9-2.5-2.52.72.52.6-2.52.4-2.2-2.3-2.0-2.3-2.0-1.5-2.0
Se content in liver0.70.81.71.21.11.1-0.91.10.9-0.8-1.11.1-0.9-0.9-0.90.30.8-0.9-0.8-0.80.8-0.80.60.70.80.70.71.30.6
Sr content in liver1.61.41.9-1.2-1.2-1.21.2-1.1-1.11.11.2-1.21.41.41.4-1.1-1.31.21.11.2-1.21.1-1.0-1.1-1.1-1.3-1.1-0.9-1.2
Zn content in liver0.10.11.20.20.10.10.10.1-0.20.1-0.10.1-0.1-0.1-0.1-0.1-0.2-0.0-0.2-0.20.2-0.30.40.30.50.30.41.10.5
Bone: minimum diameter0.50.91.90.70.70.7-0.91.00.9-0.8-1.11.0-1.1-1.1-1.10.91.4-1.1-0.6-1.00.9-0.90.60.90.71.20.90.61.1
Time in familiar zone, hab. session 11.61.82.8-1.2-1.2-1.21.1-1.2-0.91.21.2-1.31.31.31.3-1.4-0.91.31.41.4-1.51.5-1.6-1.5-1.4-1.7-1.4-1.3-1.6
Time in novel zone, hab. session 11.21.32.50.80.90.9-1.00.90.8-1.0-1.00.9-1.0-1.0-1.01.51.1-1.1-1.2-1.31.3-1.31.21.31.41.41.40.81.6
Total zone transitions, hab. session 13.24.55.8-2.3-2.0-2.02.0-2.1-1.92.02.1-2.22.12.12.1-2.0-1.82.22.22.2-2.22.2-2.1-2.2-2.2-2.4-2.1-2.2-2.1
Total locomotion distance, hab. session 10.91.22.1-1.5-1.2-1.21.1-1.1-1.11.11.0-1.21.11.11.1-0.9-1.01.21.11.1-1.11.1-0.9-1.0-1.0-1.3-0.9-1.1-1.0
Locomotion velocity, hab. session 10.81.21.8-1.3-1.1-1.11.1-1.1-1.01.01.0-1.11.01.01.0-1.0-1.11.21.11.2-1.11.1-1.0-1.1-1.0-1.3-1.0-1.0-1.1
Time in familiar zone, hab. session 22.32.63.4-1.8-1.7-1.71.7-1.6-1.61.61.7-1.71.71.71.7-1.5-1.61.71.61.7-1.71.6-1.5-1.6-1.4-1.7-1.3-1.3-1.4
Time in novel zone, hab. session 25.25.66.72.62.42.4-2.52.42.4-2.4-2.52.6-2.5-2.5-2.52.32.4-2.6-2.4-2.52.5-2.32.12.31.92.51.91.92.1
Total zone transitions, hab. session 20.91.12.0-1.2-1.2-1.21.2-1.2-1.20.91.3-1.31.41.41.4-0.6-1.31.30.71.0-0.90.8-0.3-0.7-0.7-1.0-0.7-0.7-0.7
Total locomotion distance, hab. session 20.10.10.30.10.10.1-0.10.2-0.0-0.4-0.10.0-0.0-0.0-0.00.5-0.20.0-0.4-0.20.3-0.30.60.40.40.00.40.40.3
Locomotion velocity, hab. session 20.10.10.30.10.20.2-0.20.30.1-0.4-0.20.1-0.1-0.1-0.10.4-0.1-0.0-0.5-0.30.3-0.40.50.40.40.10.40.40.3
Novel to familiar place preference ratio0.10.20.70.3-0.0-0.00.1-0.10.10.3-0.20.10.00.00.0-0.8-0.30.00.60.4-0.50.6-0.8-0.6-0.6-0.3-0.7-0.5-0.7
Novelty place preference0.00.00.20.3-0.0-0.00.0-0.10.00.2-0.20.2-0.0-0.0-0.0-0.5-0.2-0.10.30.2-0.20.2-0.4-0.3-0.30.0-0.3-0.2-0.3
Time in novel zone, NPP test0.10.10.30.0-0.3-0.30.3-0.3-0.20.40.0-0.10.20.20.2-0.5-0.40.20.40.3-0.40.3-0.4-0.4-0.3-0.1-0.4-0.3-0.3
Total zone transitions, NPP test1.72.53.1-1.7-1.7-1.71.5-1.5-1.41.31.7-1.81.81.81.8-1.3-1.41.71.51.6-1.61.5-1.3-1.5-1.6-1.7-1.4-1.4-1.5
Total locomotion distance, NPP test0.50.81.5-0.9-0.8-0.80.7-0.5-0.50.50.7-0.80.60.60.6-0.7-0.70.81.00.9-1.01.1-1.0-1.0-1.2-1.2-1.1-1.0-1.1
Locomotion velocity, NPP test0.30.51.4-0.5-0.4-0.40.3-0.2-0.10.20.3-0.50.30.30.3-0.6-0.40.50.80.7-0.80.9-1.0-1.0-1.2-1.1-1.1-0.9-1.1
Intraocular pressure1.82.96.5-1.1-0.8-0.81.1-1.1-0.71.41.0-1.31.31.31.3-2.1-0.91.12.41.9-2.02.3-2.6-2.3-2.3-2.0-2.3-2.2-2.2
Delta distance traveled before/after self-admin1.11.22.7-1.3-1.5-1.51.5-1.2-1.61.41.3-1.11.11.11.1-0.9-1.61.40.81.0-0.90.6-0.4-0.6-0.4-0.6-0.20.2-0.2
Delta ambulatory time before/after self-admin0.50.92.2-1.1-1.3-1.31.3-1.1-1.51.21.3-1.11.01.01.0-0.8-1.51.30.60.9-0.80.6-0.3-0.5-0.3-0.6-0.20.1-0.1
Parametrial fat weight3.78.817.8-3.5-3.6-3.63.8-3.9-4.23.53.9-3.94.04.04.0-1.7-3.63.61.92.5-2.11.5-0.7-1.3-0.4-1.4-0.5-1.6-0.3
Pavlov. Cond. lever latency0.40.51.2-0.4-0.4-0.40.5-0.5-0.40.50.4-0.60.60.60.6-0.9-0.60.60.70.8-0.80.9-0.9-0.9-0.7-1.1-0.7-0.8-1.0
Pavlov. Cond. magazine entry latency0.20.31.00.30.10.1-0.10.2-0.1-0.20.10.2-0.1-0.1-0.10.50.3-0.2-0.7-0.60.6-0.80.90.81.00.80.70.81.0
Pavlov. Cond. change in total contacts0.60.61.60.70.80.8-0.90.90.9-1.0-0.70.7-0.8-0.8-0.80.81.3-0.9-0.7-0.80.8-0.70.70.70.60.70.50.60.8
Pavlov. Cond. index score0.30.41.30.30.10.1-0.20.2-0.0-0.30.00.3-0.2-0.2-0.20.80.3-0.3-0.9-0.70.8-0.91.11.01.01.00.81.01.2
Pavlov. Cond. latency score0.60.72.00.40.20.2-0.40.40.1-0.5-0.10.5-0.4-0.4-0.41.10.5-0.5-1.1-0.91.0-1.21.41.21.21.31.11.21.4
Pavlov. Cond. lever contacts0.40.41.10.50.40.4-0.50.50.3-0.5-0.30.6-0.5-0.5-0.50.60.6-0.6-0.7-0.70.8-0.80.80.80.71.10.70.70.9
Pavlov. Cond. magazine entry number0.00.00.20.00.10.1-0.0-0.00.10.1-0.30.1-0.1-0.1-0.1-0.3-0.2-0.10.30.2-0.20.3-0.4-0.3-0.4-0.2-0.1-0.3-0.4
Pavlov. Cond. intertrial magazine entries1.21.52.6-1.1-0.8-0.80.9-1.0-0.70.90.8-1.11.01.01.0-1.5-0.91.01.41.3-1.41.5-1.5-1.5-1.4-1.6-1.4-1.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.30.31.10.30.10.1-0.20.20.0-0.30.00.3-0.2-0.2-0.20.70.3-0.2-0.8-0.60.7-0.81.00.90.90.80.70.91.0
Pavlov. Cond. response bias0.10.10.40.0-0.1-0.10.00.0-0.2-0.10.2-0.00.00.00.00.30.1-0.0-0.4-0.30.4-0.40.60.50.70.50.40.40.7
Pavlov. Cond. lever latency0.30.41.1-0.6-0.8-0.80.9-0.8-1.10.70.8-0.60.60.60.6-0.3-1.10.90.10.4-0.30.10.4-0.00.2-0.30.20.40.2
Pavlov. Cond. magazine entry latency1.11.62.61.31.31.3-1.41.21.3-1.3-1.21.2-1.2-1.2-1.21.21.6-1.4-1.3-1.41.4-1.31.11.31.31.41.10.81.1
Pavlov. Cond. change in total contacts0.30.61.21.11.01.0-1.00.91.1-0.8-1.01.1-1.0-1.0-1.00.41.0-1.0-0.5-0.70.6-0.50.20.40.20.70.30.40.3
Pavlov. Cond. index score0.40.71.81.01.11.1-1.21.01.3-1.0-1.10.9-0.9-0.9-0.90.41.4-1.1-0.3-0.70.6-0.3-0.10.30.10.60.0-0.20.1
Pavlov. Cond. latency score0.50.82.21.11.21.2-1.31.11.5-1.1-1.21.0-1.0-1.0-1.00.51.5-1.2-0.4-0.80.6-0.4-0.10.30.10.60.0-0.20.1
Pavlov. Cond. lever contacts0.20.20.80.50.70.7-0.70.60.8-0.6-0.60.5-0.5-0.5-0.50.30.9-0.7-0.2-0.40.4-0.2-0.10.20.00.50.1-0.30.1
Pavlov. Cond. magazine entry number1.21.62.4-1.5-1.4-1.41.4-1.3-1.41.31.3-1.31.21.21.2-1.1-1.61.41.21.4-1.31.2-1.0-1.2-1.1-1.4-1.0-0.8-1.0
Pavlov. Cond. intertrial magazine entries1.53.44.4-2.1-2.0-2.02.1-1.9-2.02.01.7-1.81.71.71.7-2.1-2.01.91.92.0-1.91.8-1.6-1.7-1.6-1.9-1.4-1.5-1.3
Pavlov. Cond. lever-magazine prob. diff.0.40.61.71.01.11.1-1.11.01.3-0.9-1.00.9-0.8-0.8-0.80.51.3-1.1-0.3-0.70.6-0.3-0.10.30.10.50.0-0.20.1
Pavlov. Cond. response bias0.40.61.60.80.90.9-1.00.91.1-0.9-0.90.8-0.7-0.7-0.70.71.3-1.0-0.5-0.80.7-0.50.20.50.40.90.40.10.4
Time in closed arm before self-admin0.20.31.4-0.2-0.3-0.30.4-0.5-0.70.20.3-0.20.30.30.30.4-1.10.5-0.7-0.20.3-0.61.00.60.90.21.20.50.7
Time in closed arm after self-admin0.70.81.40.71.11.1-0.90.80.8-1.0-0.80.8-0.7-0.7-0.71.00.9-0.9-1.2-1.01.0-1.11.21.01.00.51.00.80.6
Time in open arm before self-admin1.01.25.01.01.11.1-1.51.41.7-1.1-1.31.2-1.3-1.3-1.31.02.2-1.5-0.3-0.90.8-0.4-0.20.40.00.8-0.3-0.00.4
Time in open arm after self-admin0.30.31.50.0-0.4-0.4-0.00.10.30.30.5-0.30.20.20.2-0.30.7-0.11.00.4-0.50.8-1.2-0.8-1.20.0-1.2-0.7-0.5
Bone: periosteal estimation0.10.20.60.60.40.4-0.40.60.5-0.2-0.60.7-0.7-0.7-0.7-0.20.8-0.50.0-0.30.2-0.1-0.30.1-0.10.40.20.20.3
Bone: periosteal perimeter0.20.31.5-0.2-0.3-0.30.4-0.3-0.20.70.1-0.10.10.10.1-1.2-0.10.30.90.7-0.70.8-1.0-0.8-0.9-0.4-0.8-0.5-0.7
Bone: post-yield work0.10.10.4-0.4-0.4-0.40.5-0.5-0.60.40.6-0.40.40.40.40.0-0.40.5-0.10.10.0-0.20.30.20.30.10.20.20.4
Progressive ratio test 1 active lever presses0.61.01.9-1.1-1.0-1.00.9-1.1-0.71.20.8-0.80.80.80.8-1.20.00.61.41.0-1.11.1-1.3-1.1-1.2-0.7-1.4-1.4-0.7
Progressive ratio test 1 breakpoint0.71.22.2-1.2-1.1-1.11.0-1.1-0.81.30.9-0.90.90.90.9-1.3-0.10.71.41.1-1.21.2-1.4-1.1-1.3-0.8-1.5-1.5-0.8
Progressive ratio test 1 inactive lever presses0.10.31.50.60.40.4-0.60.50.7-0.2-0.70.7-0.6-0.6-0.6-0.31.2-0.70.2-0.10.00.1-0.5-0.1-0.5-0.1-0.4-0.3-0.4
Progressive ratio test 2 active lever presses3.55.07.2-2.3-2.5-2.52.1-2.2-1.92.52.2-2.02.12.12.1-2.6-0.81.72.72.3-2.42.3-2.5-2.3-2.4-2.0-2.5-2.4-1.7
Progressive ratio test 2 breakpoint3.95.07.3-2.3-2.5-2.52.2-2.2-2.02.52.2-2.02.12.12.1-2.6-0.81.72.72.4-2.42.3-2.5-2.3-2.4-2.0-2.5-2.3-1.7
Progressive ratio test 2 inactive lever presses0.82.44.2-1.5-1.7-1.71.3-1.4-1.01.81.4-1.21.31.31.3-1.90.00.92.11.6-1.71.7-2.0-1.7-2.0-1.4-2.0-2.0-1.3
Incentive Sensitization - Responses1.84.96.9-2.5-2.6-2.62.2-2.1-2.12.52.1-2.02.22.22.2-2.5-0.91.72.62.3-2.42.3-2.3-2.2-2.3-2.1-2.1-1.9-1.5
Incentive Sensitization - Breakpoint1.84.25.9-2.3-2.4-2.42.1-2.0-1.92.32.0-1.92.02.02.0-2.3-0.91.62.42.2-2.22.1-2.1-2.0-2.1-1.9-2.0-1.7-1.5
Sum of active levers in priming session hrs 5-62.12.03.9-1.7-1.7-1.71.9-1.9-2.01.91.9-1.51.71.71.7-1.2-1.01.51.31.2-1.10.9-0.6-0.7-0.6-0.3-0.9-0.90.2
Progressive ratio0.00.10.80.2-0.2-0.2-0.0-0.20.10.10.10.20.10.10.1-0.4-0.10.10.10.3-0.30.3-0.3-0.3-0.5-0.5-0.6-0.2-0.9
Food seeking constrained by brief footshock0.10.10.40.30.30.3-0.30.50.3-0.5-0.30.2-0.2-0.2-0.20.10.1-0.2-0.4-0.20.2-0.20.30.20.3-0.00.30.70.2
Seeking ratio, punishment vs. effort0.51.22.30.81.11.1-1.01.21.0-1.1-1.10.8-1.0-1.0-1.01.21.1-1.1-1.0-1.11.1-1.01.01.11.21.11.20.91.5
Retroperitoneal fat weight0.41.63.9-1.9-1.3-1.31.3-1.4-1.31.21.5-2.01.81.81.8-0.3-0.51.11.21.0-1.01.0-0.9-0.9-0.7-0.7-0.7-1.5-0.4
Reaction time number correct0.00.10.4-0.1-0.1-0.10.4-0.2-0.40.50.0-0.00.00.00.0-0.6-0.40.30.30.3-0.30.2-0.2-0.2-0.2-0.1-0.10.00.1
Reaction time mean minus median0.00.10.60.00.30.3-0.20.10.3-0.4-0.2-0.10.10.10.1-0.0-0.20.0-0.00.1-0.20.3-0.2-0.3-0.3-0.7-0.5-0.4-0.7
Reaction time mean minus median AUC0.21.32.9-1.0-0.7-0.70.9-1.0-0.80.80.7-1.01.01.01.0-1.3-1.51.21.01.2-1.21.3-1.0-1.3-1.1-1.7-1.3-1.2-1.5
Reaction time num false alarms0.81.33.6-0.8-0.7-0.70.6-0.7-0.40.70.8-0.80.70.70.7-1.1-0.60.81.41.2-1.31.5-1.6-1.5-1.7-1.6-1.9-1.4-1.8
Reaction time num false alarms AUC0.51.13.1-0.6-0.6-0.60.5-0.6-0.30.60.6-0.50.60.60.6-1.0-0.50.71.21.1-1.21.3-1.5-1.4-1.6-1.5-1.8-1.2-1.6
Reaction time trials correct on left0.00.10.4-0.1-0.1-0.10.4-0.2-0.40.50.0-0.00.00.00.0-0.6-0.40.30.30.3-0.30.2-0.2-0.2-0.2-0.1-0.10.00.1
Reaction time trials on left0.00.10.4-0.1-0.1-0.10.4-0.2-0.40.50.0-0.00.00.00.0-0.7-0.40.30.30.3-0.30.3-0.3-0.2-0.2-0.2-0.20.00.1
Reaction time mean0.00.10.7-0.10.20.2-0.50.30.5-0.6-0.50.1-0.0-0.0-0.00.80.2-0.3-0.4-0.40.3-0.20.40.30.2-0.00.2-0.00.0
Reaction time mean AUC0.10.10.60.10.40.4-0.60.50.7-0.8-0.60.3-0.2-0.2-0.20.70.2-0.4-0.4-0.30.3-0.20.30.10.0-0.10.0-0.1-0.2
Median of all reaction times0.10.21.1-0.00.30.3-0.60.40.5-0.7-0.50.3-0.2-0.2-0.21.00.4-0.5-0.5-0.50.5-0.40.60.50.40.30.50.10.3
Reaction time omissions0.00.00.1-0.0-0.1-0.1-0.0-0.00.0-0.10.1-0.10.10.10.10.0-0.20.2-0.10.00.00.00.1-0.00.2-0.10.1-0.10.0
Reaction time false alarm rate0.50.72.2-0.6-0.6-0.60.4-0.5-0.20.40.6-0.50.50.50.5-0.6-0.40.50.90.9-1.01.1-1.2-1.1-1.3-1.3-1.5-1.1-1.5
Reaction time premature initiation rate0.61.01.6-1.2-1.0-1.01.1-1.1-1.11.21.2-1.21.31.31.3-0.7-0.91.10.91.0-0.90.8-0.6-0.8-0.6-0.9-0.7-0.4-0.8
Reaction time premature initiations0.41.21.8-1.1-1.1-1.11.3-1.2-1.31.41.2-1.21.31.31.3-1.1-1.11.31.01.2-1.10.9-0.8-0.9-0.8-1.1-0.8-0.5-0.8
Std. dev. reaction times0.00.10.40.20.30.3-0.30.20.4-0.5-0.50.2-0.1-0.1-0.10.1-0.2-0.1-0.2-0.0-0.00.10.0-0.2-0.1-0.6-0.3-0.1-0.6
Reaction time trials completed0.00.10.4-0.1-0.1-0.10.4-0.2-0.40.50.0-0.00.00.00.0-0.7-0.40.30.30.3-0.30.3-0.3-0.2-0.2-0.2-0.20.00.1
Reaction time trials AUC0.00.10.6-0.0-0.1-0.10.4-0.2-0.30.50.00.00.00.00.0-0.8-0.50.30.40.3-0.30.3-0.3-0.3-0.3-0.2-0.2-0.00.0
Run reversals in cocaine runway, females0.20.21.6-0.20.10.10.2-0.2-0.10.20.0-0.20.20.20.2-0.5-0.30.20.40.5-0.50.5-0.5-0.6-0.6-1.0-0.8-0.4-1.2
Run reversals in cocaine runway, males1.51.64.0-1.0-1.0-1.00.9-1.2-0.71.01.1-1.21.11.11.1-1.2-0.90.91.51.3-1.41.5-1.7-1.5-1.6-1.3-1.7-2.0-1.4
Latency to leave start box in cocaine runway0.50.61.80.80.80.8-0.70.80.6-0.8-0.80.9-0.8-0.8-0.80.70.3-0.6-1.0-0.80.8-0.80.90.80.90.60.71.30.5
Latency to leave start box in cocaine runway, F1.41.75.41.21.21.2-1.01.20.7-1.2-1.11.2-1.1-1.1-1.11.30.3-0.8-1.7-1.31.4-1.51.81.51.71.01.52.31.1
Latency to leave start box in cocaine runway, M0.20.20.7-0.4-0.4-0.40.3-0.4-0.10.50.3-0.30.30.30.3-0.4-0.00.20.60.4-0.50.5-0.7-0.5-0.6-0.3-0.6-0.9-0.3
Std. dev. time between licks in bursts0.20.40.6-0.6-0.7-0.70.6-0.7-0.60.50.8-0.70.80.80.8-0.3-0.60.60.50.6-0.60.5-0.4-0.5-0.6-0.6-0.5-0.6-0.5
Total sessions with >9 infusions1.31.63.9-1.1-1.2-1.21.2-1.3-1.01.51.0-1.00.70.70.7-2.0-0.40.91.71.4-1.51.5-1.7-1.4-1.5-1.1-1.6-1.4-0.8
Short access day 1 total inactive lever presses0.10.20.6-0.1-0.4-0.40.5-0.4-0.40.70.6-0.30.30.30.3-0.8-0.20.40.50.5-0.50.4-0.6-0.4-0.4-0.2-0.5-0.0-0.1
Short access day 10 total inactive lever presses0.10.51.31.20.70.7-0.91.11.0-0.6-0.71.0-0.8-0.8-0.80.40.8-0.8-0.3-0.50.4-0.3-0.00.2-0.00.50.10.90.2
Short access day 1 total infusions0.30.61.9-0.4-0.6-0.60.4-0.3-0.10.70.2-0.1-0.1-0.1-0.1-1.30.00.21.10.8-0.91.0-1.4-1.0-1.2-0.7-1.3-0.9-0.8
Short access day 10 total infusions1.22.04.6-1.3-1.1-1.11.1-1.1-0.81.40.8-1.10.90.90.9-2.0-0.20.82.01.5-1.61.7-2.1-1.7-2.0-1.2-1.8-1.9-1.1
Short access total infusions0.40.61.8-0.5-0.5-0.50.4-0.5-0.20.70.3-0.40.20.20.2-1.20.20.21.10.8-0.91.0-1.3-1.0-1.2-0.7-1.2-1.1-0.7
Short access day 1 locomotion0.20.31.10.2-0.0-0.0-0.10.10.40.3-0.30.5-0.7-0.7-0.7-1.01.0-0.40.80.3-0.40.6-1.1-0.6-0.9-0.1-0.8-0.7-0.0
Short access day 10 total locomotion0.00.20.80.2-0.1-0.1-0.20.30.40.2-0.30.5-0.4-0.4-0.4-0.60.7-0.20.60.2-0.40.5-0.9-0.5-0.7-0.2-0.5-0.1-0.2
Short access total locomotion0.30.41.60.30.10.1-0.20.30.50.3-0.40.6-0.7-0.7-0.7-1.11.0-0.40.80.4-0.50.7-1.3-0.7-1.0-0.4-0.9-0.6-0.3
One hour access (0.3 mA shock)2.93.44.2-1.9-2.0-2.01.8-2.0-1.71.91.8-1.91.91.91.9-1.8-1.31.62.01.9-1.91.9-1.9-1.8-1.8-1.6-1.9-1.9-1.6
Compulsive drug intake0.30.51.80.1-0.1-0.10.00.1-0.3-0.20.3-0.10.40.40.41.1-0.30.1-1.0-0.60.7-0.91.31.01.30.71.31.20.9
One hour access (shock baseline)0.51.43.2-1.0-1.0-1.00.9-1.1-0.71.20.6-0.80.60.60.6-1.5-0.40.81.61.3-1.31.4-1.7-1.4-1.6-1.1-1.6-1.8-0.9
Social response proportion0.60.72.3-0.1-0.4-0.40.5-0.5-0.90.30.5-0.20.40.40.40.7-0.60.4-0.9-0.40.6-1.01.51.11.50.91.41.41.4
Social responses0.40.61.6-0.8-0.9-0.91.0-1.0-1.30.81.1-0.90.90.90.9-0.1-1.31.10.10.4-0.30.00.40.10.3-0.10.30.20.4
Social time0.30.53.0-0.6-0.5-0.50.9-1.0-1.10.50.9-0.90.80.80.80.0-1.71.1-0.40.3-0.1-0.20.60.20.8-0.20.40.40.1
Soleus weight1.34.09.7-2.4-2.6-2.62.7-2.8-3.12.62.6-2.32.52.52.5-1.5-2.42.51.11.5-1.30.7-0.0-0.50.2-0.60.2-0.70.1
Bone: stiffness0.20.30.7-0.2-0.6-0.60.5-0.5-0.70.50.7-0.30.50.50.50.3-0.40.5-0.3-0.10.2-0.50.60.50.80.60.60.60.8
Tibialis anterior weight7.626.335.9-5.5-6.0-6.05.8-5.8-5.85.65.9-5.55.65.65.6-4.9-6.05.94.65.2-5.04.4-3.5-4.3-3.6-4.5-3.5-3.6-3.7
Time to tail flick, vehicle, before self-admin3.84.67.8-2.4-2.5-2.52.6-2.4-2.82.42.4-2.42.52.52.5-2.0-2.82.61.72.1-2.01.7-1.2-1.6-1.2-1.9-1.1-1.0-1.3
Time to tail flick, vehicle, after self-admin0.10.10.8-0.4-0.2-0.20.4-0.4-0.50.30.3-0.40.50.50.5-0.2-0.90.50.00.3-0.20.10.1-0.10.0-0.4-0.30.1-0.7
Time to tail flick, test, before self-admin0.70.82.40.80.50.5-0.40.40.1-0.8-0.40.7-0.6-0.6-0.60.8-1.00.0-1.5-0.80.9-1.11.51.11.50.31.51.50.3
Time to tail flick, test, after self-admin0.50.61.90.80.60.6-0.70.60.6-0.9-0.60.5-0.5-0.5-0.51.40.5-0.7-1.0-0.90.9-0.91.00.90.80.70.60.50.7
Delta time to tail flick, vehicle, before/after SA0.91.02.11.31.41.4-1.31.21.4-1.3-1.31.2-1.3-1.3-1.30.80.6-1.1-0.8-0.80.7-0.50.30.50.30.40.00.5-0.2
Delta time to tail flick, test, before/after SA0.60.72.7-0.6-0.6-0.60.4-0.4-0.20.60.6-0.80.70.70.7-0.40.50.11.30.7-0.91.0-1.3-1.0-1.4-0.6-1.6-1.4-0.5
Tibia length1.33.78.11.51.21.2-1.51.41.1-1.7-1.01.4-1.1-1.1-1.12.41.4-1.5-2.5-2.22.3-2.52.82.52.62.62.32.32.3
Ambulatory time before self-admin1.13.48.71.92.02.0-2.31.92.4-2.0-2.12.0-1.8-1.8-1.81.92.9-2.3-1.5-1.91.8-1.51.11.51.11.71.00.31.3
Ambulatory time after self-admin0.50.82.20.60.70.7-0.80.70.6-0.6-0.80.9-0.8-0.8-0.81.11.1-0.8-0.9-1.01.0-1.10.91.11.11.21.00.71.5
Bone: tissue strength2.62.74.72.21.91.9-1.81.81.8-1.7-1.51.8-1.8-1.8-1.81.51.8-1.7-1.7-1.71.6-1.51.31.51.31.51.11.41.1
Total heroin consumption3.54.18.1-2.4-2.7-2.72.6-2.5-2.82.52.8-2.52.72.72.7-1.3-2.12.31.41.7-1.51.1-0.5-0.9-0.6-1.0-0.9-0.2-0.5
Bone: trabecular number3.56.510.4-3.0-3.0-3.03.0-3.0-3.12.73.2-3.23.03.03.0-1.9-3.03.02.02.4-2.31.9-1.4-1.8-1.5-1.9-1.6-1.6-1.5
Bone: trabecular spacing0.20.20.70.70.50.5-0.60.60.7-0.4-0.60.8-0.6-0.6-0.60.10.8-0.70.1-0.30.2-0.0-0.3-0.0-0.20.3-0.00.1-0.0
Bone: trabecular thickness0.10.20.5-0.5-0.7-0.70.5-0.6-0.60.40.6-0.50.50.50.5-0.1-0.70.60.00.3-0.20.10.2-0.1-0.1-0.4-0.1-0.1-0.2
Bone: trabecular tissue density1.42.54.21.61.71.7-1.92.02.0-2.0-1.81.6-1.7-1.7-1.71.72.1-1.9-1.3-1.61.5-1.21.11.20.81.10.81.01.0
Water consumed over 24 hours1.12.13.51.41.31.3-1.21.21.0-1.3-1.21.3-1.4-1.4-1.41.71.2-1.2-1.7-1.61.6-1.71.81.71.91.61.71.51.7
Number of responses in last shaping day0.30.41.70.50.10.1-0.30.30.70.00.00.2-0.4-0.4-0.4-0.50.8-0.40.80.3-0.50.8-1.3-0.8-1.1-0.2-1.2-0.9-0.4