Tm7sf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Tm7sf2 0.24 0.1 8.0e-15 0.24 0.26 0.25 0.26 3.1e-13 3.9e-14 1.0e-13 6.7e-14
2 IL gene expression Tm7sf2 0.18 0.12 1.9e-03 0.11 0.12 0.06 0.09 1.6e-03 9.8e-04 1.7e-02 3.6e-03
3 Liver isoform ratio NM_001013071.1 0.03 0.02 2.5e-03 0.01 0.01 0.01 0.01 8.4e-03 6.7e-03 5.5e-02 1.5e-02
4 Liver isoform ratio XM_039108440.2 0.03 0.02 1.4e-03 0.01 0.02 0.01 0.01 2.0e-02 5.1e-03 3.4e-02 1.3e-02
5 Liver gene expression Tm7sf2 0.2 0.1 1.1e-15 0.1 0.1 0.1 0.11 7.8e-11 2.2e-11 1.1e-10 3.8e-12
6 OFC gene expression Tm7sf2 0.23 0.11 2.7e-05 0.23 0.2 0.21 0.22 4.2e-06 1.3e-05 9.1e-06 7.3e-06
7 Brain gene expression Tm7sf2 0.28 0.11 0.0e+00 0.27 0.26 0.27 0.27 4.4e-25 3.7e-24 7.4e-25 2.8e-25
8 pVTA gene expression Tm7sf2 0.3 0.11 0.0e+00 0.33 0.32 0.33 0.33 6.8e-27 7.9e-26 1.3e-27 1.2e-27
9 NAcc gene expression Tm7sf2 0.12 0.06 0.0e+00 0.16 0.14 0.16 0.16 1.0e-23 2.9e-21 5.9e-23 3.7e-23
10 IC gene expression Tm7sf2 0.27 0.11 3.1e-11 0.17 0.1 0.16 0.17 7.8e-08 4.8e-05 4.2e-07 1.3e-07
11 NAcc mRNA stability Tm7sf2 0.04 0.03 1.0e-07 0.05 0.05 0.06 0.05 2.2e-08 2.3e-08 1.0e-08 1.6e-08
12 Brain mRNA stability Tm7sf2 0.05 0.03 1.1e-04 0.04 0.04 0.03 0.03 1.9e-04 2.5e-04 3.7e-04 3.4e-04
13 PL gene expression Tm7sf2 0.21 0.13 0.0e+00 0.22 0.2 0.21 0.21 1.4e-23 6.2e-21 5.2e-23 1.0e-22
14 Adipose gene expression Tm7sf2 0.17 0.07 2.2e-16 0.07 0.1 0.08 0.1 1.1e-08 1.7e-11 5.6e-09 1.0e-10
15 IC mRNA stability Tm7sf2 0.07 0.05 7.0e-03 0.01 0.01 0.02 0.01 1.3e-01 1.0e-01 4.5e-02 1.8e-01
16 PL mRNA stability Tm7sf2 0.05 0.03 1.1e-05 0.04 0.05 0.05 0.05 9.9e-05 5.1e-06 5.3e-06 3.2e-06
17 LHb gene expression Tm7sf2 0.23 0.13 1.9e-04 0.13 0.15 0.17 0.12 6.9e-04 2.3e-04 8.5e-05 9.6e-04
18 Adipose mRNA stability Tm7sf2 0.04 0.03 3.4e-04 0.02 0.02 0.02 0.02 2.5e-03 2.9e-03 3.4e-03 3.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.50.92.0-1.1-1.3-1.31.4-0.90.9-0.8-1.00.80.90.80.70.90.3-0.31.00.8-1.2
Area under the delay curve0.00.10.40.0-0.2-0.10.10.2-0.20.30.1-0.0-0.00.2-0.00.10.6-0.50.1-0.30.0
BMI with tail1.86.213.3-3.0-3.3-3.43.6-2.52.5-2.2-2.62.32.42.32.32.30.6-0.22.22.8-2.1
BMI without tail0.42.04.1-1.8-1.9-1.92.0-1.41.4-1.3-1.61.51.51.71.41.40.10.30.51.0-0.5
Body weight2.711.717.0-4.0-3.8-4.14.1-3.73.7-3.6-3.93.73.73.73.73.6-1.92.2-0.14.0-0.0
Weight adjusted by age0.61.92.4-1.5-1.4-1.41.4-1.41.4-1.5-1.31.51.51.41.51.4-1.51.4-1.01.30.0
Bone surface4.28.213.8-3.4-3.6-3.63.7-3.23.2-3.1-3.23.03.12.63.03.1-1.61.30.32.8-0.6
Bone volume1.53.06.4-2.1-2.4-2.42.5-1.81.8-1.7-1.91.71.81.31.71.8-0.40.11.01.4-1.1
Breakpoint value in progressive ratio session2.03.65.4-2.2-2.3-2.22.2-2.22.2-2.2-2.12.02.01.81.92.1-1.51.2-0.91.50.0
Number of licking bursts0.10.40.6-0.7-0.8-0.70.7-0.60.6-0.7-0.70.60.60.50.70.6-0.40.3-0.20.50.1
Context. condit. distance diff. score1.92.32.91.71.61.6-1.61.7-1.71.71.7-1.7-1.6-1.4-1.7-1.51.5-1.30.9-1.3-1.0
Locomotion velocity, session 10.10.10.40.00.40.2-0.30.0-0.00.00.00.10.10.40.10.1-0.40.6-0.40.30.5
Locomotion distance, session 10.40.50.9-0.9-0.8-0.90.9-0.70.7-0.6-0.70.80.80.90.70.60.10.20.41.0-0.4
Locomotion velocity, session 22.53.04.2-2.0-1.9-2.02.0-1.81.8-1.8-1.91.91.92.01.81.9-1.01.1-0.31.9-0.0
Locomotion distance, session 20.60.81.3-1.1-1.0-1.01.1-1.01.0-0.8-1.01.01.01.20.90.8-0.20.5-0.11.10.1
Locomotion velocity, session 30.50.52.50.30.40.2-0.10.3-0.30.50.4-0.4-0.4-0.5-0.5-0.71.1-0.71.50.9-1.6
Locomotion distance, session 30.00.00.10.20.20.2-0.20.0-0.00.10.2-0.2-0.2-0.2-0.2-0.20.2-0.10.10.2-0.2
Stereotopy head waving bouts, day 30.81.03.10.70.80.6-0.60.9-0.91.00.8-0.8-0.9-0.7-0.8-1.11.4-0.91.80.6-1.5
Stereotopy head waving duration, day 30.70.91.90.80.80.7-0.61.0-1.01.10.9-0.9-0.9-0.9-0.9-1.11.2-1.01.4-0.3-1.2
Locomotion velocity, session 70.70.82.80.40.10.2-0.00.7-0.60.80.6-0.6-0.6-0.8-0.7-0.81.6-1.41.50.0-1.7
Locomotion distance, session 70.10.10.50.10.20.1-0.10.0-0.00.1-0.0-0.2-0.2-0.0-0.2-0.40.6-0.30.50.7-0.6
Stereotopy head waving bouts, day 70.20.20.8-0.1-0.4-0.30.40.2-0.20.20.1-0.2-0.1-0.3-0.1-0.00.6-0.90.9-0.2-0.9
Stereotopy head waving duration, day 70.60.82.2-1.1-1.5-1.31.4-0.80.8-0.7-0.80.91.00.71.01.0-0.1-0.20.20.3-0.2
Locomotion velocity, session 81.01.23.6-0.9-0.4-0.70.6-1.11.1-1.2-1.11.11.01.41.01.1-1.31.6-0.91.90.7
Locomotion distance, session 80.40.51.90.40.40.3-0.20.6-0.60.70.5-0.5-0.5-0.5-0.6-0.61.1-0.91.30.2-1.4
Degree of sensitization distance0.10.21.0-0.1-0.0-0.20.20.0-0.00.0-0.2-0.00.00.0-0.1-0.30.6-0.31.00.8-0.8
Degree of sensitization stereotypy0.40.51.5-0.8-1.2-1.11.1-0.70.7-0.7-0.60.60.70.40.70.8-0.1-0.30.20.1-0.3
Conditioned locomotion1.61.82.6-1.5-1.2-1.41.3-1.41.4-1.4-1.41.51.41.41.61.3-1.31.4-0.71.60.7
Cocaine response after cond. corrected1.11.62.71.41.61.5-1.51.5-1.51.51.4-1.3-1.4-1.1-1.3-1.51.1-0.60.7-0.1-0.6
Cocaine response after cond. not corrected0.81.22.01.21.41.3-1.31.2-1.21.21.2-1.1-1.2-0.9-1.2-1.21.0-0.60.70.2-0.7
Cocaine response before conditioning0.70.91.5-1.0-1.2-1.11.1-1.11.1-1.1-1.00.91.00.80.91.1-0.70.4-0.40.60.4
Saline control response4.15.79.0-2.4-2.1-2.32.2-2.52.5-2.5-2.52.52.52.72.62.6-2.22.4-1.43.01.4
Bone: connectivity density2.33.66.2-2.3-2.4-2.42.5-2.22.2-2.0-2.11.92.01.91.92.1-0.70.70.32.0-0.6
Bone: cortical apparent density0.20.31.7-0.1-0.2-0.10.0-0.40.3-0.4-0.20.30.30.20.30.3-0.60.4-1.3-0.91.3
Bone: cortical area0.71.12.1-1.2-1.1-1.21.2-1.11.1-1.1-1.11.11.10.91.11.1-0.90.70.11.4-0.3
Bone: cortical porosity0.10.20.4-0.5-0.6-0.60.6-0.30.3-0.3-0.50.40.50.40.50.3-0.10.1-0.10.0-0.2
Bone: cortical porosity0.50.60.9-1.0-1.0-1.01.0-0.70.7-0.7-0.90.80.90.90.90.7-0.40.5-0.20.5-0.0
Bone: cortical thickness2.94.87.1-2.0-1.6-1.71.5-2.22.2-2.3-2.22.32.32.42.22.3-2.72.6-2.41.82.2
Bone: cortical thickness0.60.82.3-0.4-0.1-0.20.0-0.70.7-0.8-0.70.70.71.10.70.7-1.21.5-1.50.71.4
Bone: cortical tissue density0.30.52.2-0.3-0.4-0.20.1-0.50.5-0.6-0.40.50.50.40.50.4-0.80.6-1.4-0.81.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.4-0.5-0.40.5-0.30.3-0.3-0.30.40.40.40.40.3-0.00.1-0.2-0.20.2
Condit. Reinf. active-inactive response ratio0.10.10.9-0.1-0.3-0.10.10.0-0.10.0-0.00.20.10.10.20.1-0.10.1-0.7-1.00.7
Condit. Reinf. active responses0.10.10.4-0.2-0.4-0.30.4-0.10.1-0.1-0.10.10.1-0.00.1-0.00.5-0.40.60.0-0.6
Condit. Reinf. inactive responses0.40.52.70.10.0-0.10.20.2-0.10.20.2-0.4-0.3-0.5-0.3-0.41.0-0.91.50.8-1.6
Incentive salience index mean0.20.30.7-0.7-0.8-0.80.8-0.50.5-0.4-0.60.50.50.60.50.50.2-0.00.30.2-0.4
Condit. Reinf. lever presses0.50.71.5-1.0-1.1-1.11.2-0.80.8-0.8-1.00.70.70.50.70.70.0-0.00.90.9-0.9
Condit. Reinf. active minus inactive responses0.10.10.50.1-0.1-0.00.10.1-0.10.10.1-0.2-0.2-0.6-0.3-0.30.4-0.70.6-0.2-0.7
Condit. Reinf. active-inactive response ratio0.71.13.90.60.40.3-0.20.8-0.80.80.7-0.9-0.8-1.4-0.9-0.91.2-1.51.9-0.1-2.0
Condit. Reinf. active responses0.10.20.6-0.5-0.7-0.60.6-0.50.5-0.5-0.40.30.40.10.30.3-0.0-0.3-0.1-0.3-0.0
Condit. Reinf. inactive responses0.50.71.3-0.8-0.9-0.80.7-1.01.0-0.9-0.80.90.81.10.80.9-0.60.7-1.1-0.21.1
Condit. Reinf. lever presses1.72.54.2-1.9-2.0-2.02.0-1.81.8-1.8-1.91.71.71.21.71.6-1.10.7-0.11.10.0
Condit. Reinf. lever reinforcers received0.30.51.1-0.8-1.0-0.90.9-0.90.9-0.8-0.80.70.70.40.70.7-0.40.1-0.3-0.10.3
Conditioned reinforcement - actives0.00.10.4-0.2-0.3-0.30.40.1-0.1-0.1-0.1-0.10.0-0.40.10.1-0.3-0.10.60.1-0.0
Conditioned reinforcement - inactives1.33.56.32.01.61.7-1.71.9-1.91.82.1-2.1-2.1-2.5-2.1-1.81.5-2.01.5-2.1-0.8
Conditioned locomotion6.49.513.23.43.13.3-3.23.3-3.33.23.3-3.4-3.3-3.6-3.3-3.32.4-2.71.8-3.3-0.8
Patch foraging indifference point 0 sec0.00.00.10.10.10.1-0.1-0.10.1-0.10.1-0.3-0.3-0.1-0.2-0.20.3-0.30.2-0.0-0.0
Patch foraging indifference point AUC1.33.24.2-1.9-2.0-1.91.9-2.02.0-2.0-2.01.92.01.51.81.9-1.81.4-1.20.71.5
Delay disc. indifference point, 0s delay0.30.41.20.40.20.3-0.21.0-1.01.00.4-0.4-0.4-0.1-0.4-0.21.1-0.80.8-0.70.0
Delay disc. indifference point, 16s delay0.60.81.80.80.40.6-0.50.7-0.70.80.9-0.8-1.0-1.1-0.9-0.91.2-1.30.7-1.30.0
Delay disc. indifference point, 2s delay0.20.20.70.20.10.1-0.00.5-0.50.50.3-0.3-0.3-0.2-0.4-0.10.7-0.70.80.20.0
Delay disc. indifference point, 24s delay0.10.10.30.30.40.4-0.50.2-0.20.30.3-0.2-0.10.1-0.2-0.1-0.10.4-0.6-0.20.0
Delay disc. indifference point, 4s delay0.10.10.40.30.20.2-0.20.4-0.40.50.3-0.2-0.20.2-0.2-0.10.6-0.30.10.00.0
Delay disc. indifference point, 8s delay0.00.00.10.10.00.1-0.10.2-0.20.30.10.10.00.30.0-0.00.3-0.1-0.2-0.20.0
Indifference point function ln k3.711.315.33.83.93.8-3.83.6-3.63.73.8-3.7-3.8-3.2-3.5-3.73.0-2.41.9-1.8-2.4
Indifference point function log k3.711.315.33.83.93.8-3.83.6-3.63.73.8-3.7-3.8-3.2-3.5-3.73.0-2.41.9-1.8-2.4
Patch foraging total patch changes 0 sec0.00.00.10.10.20.2-0.2-0.20.2-0.2-0.0-0.2-0.10.1-0.1-0.1-0.10.2-0.20.20.4
Patch foraging total patch changes 12 sec4.45.98.0-2.7-2.7-2.62.6-2.82.8-2.8-2.82.52.62.52.52.6-1.91.8-1.41.31.9
Patch foraging total patch changes 18 sec0.30.81.4-1.0-1.2-1.11.2-1.11.1-1.0-1.11.01.00.80.91.0-0.50.30.10.40.3
Patch foraging total patch changes 24 sec0.93.03.7-1.7-1.5-1.51.5-1.91.9-1.9-1.91.81.81.81.71.8-1.91.8-1.31.61.8
Patch foraging total patch changes 6 sec0.91.52.7-1.3-1.1-1.21.1-1.71.7-1.5-1.41.21.21.41.11.2-0.91.0-0.51.30.6
Patch foraging time to switch 0 sec0.72.76.2-2.0-2.4-2.32.5-1.71.7-1.5-1.71.71.71.51.61.7-0.0-0.10.90.9-0.7
Patch foraging water rate 0 sec1.66.211.33.13.33.3-3.42.7-2.82.52.7-2.6-2.7-2.6-2.7-2.71.0-0.90.1-1.6-0.6
Patch foraging water rate 12 sec3.112.623.04.34.84.6-4.84.0-4.03.94.1-3.7-3.7-3.3-3.8-3.71.7-1.30.2-2.2-0.9
Patch foraging water rate 18 sec1.94.17.82.42.82.6-2.72.4-2.42.32.3-2.1-2.2-1.8-2.1-2.11.2-0.70.5-1.0-0.7
Patch foraging water rate 24 sec4.05.710.22.83.23.0-3.12.8-2.82.62.7-2.4-2.5-2.3-2.5-2.61.2-0.90.6-1.1-1.1
Patch foraging water rate 6 sec4.26.213.23.13.63.4-3.52.7-2.72.62.7-2.5-2.6-2.2-2.6-2.81.1-0.50.2-0.8-0.8
Seeking ratio, delayed vs. immediate footshock0.10.20.70.40.00.2-0.10.1-0.10.20.3-0.5-0.5-0.4-0.2-0.50.9-0.80.1-0.20.0
Distance traveled before self-admin0.40.82.1-1.1-1.5-1.31.4-0.90.9-0.9-1.00.90.90.71.01.1-0.2-0.10.30.40.0
Distance traveled after self-admin0.20.30.6-0.6-0.8-0.60.6-0.60.6-0.7-0.50.50.50.40.50.6-0.50.3-0.7-0.20.0
Extensor digitorum longus weight7.228.936.6-6.0-5.7-5.95.8-5.85.8-5.7-5.95.95.95.85.95.8-4.34.4-2.45.02.4
Bone: elastic displacement1.01.23.41.41.81.7-1.81.1-1.11.01.1-1.0-1.0-0.7-1.0-1.1-0.10.4-0.6-0.20.6
Bone: elastic work0.91.23.2-0.8-0.3-0.50.4-1.01.0-1.1-1.01.01.01.51.01.0-1.41.8-1.31.31.3
Bone: endosteal estimation1.02.511.00.80.60.5-0.31.1-1.11.21.0-1.3-1.3-1.3-1.3-1.12.2-2.03.20.3-3.3
Bone: endosteal perimeter1.33.213.10.90.60.5-0.31.4-1.41.51.2-1.4-1.5-1.8-1.4-1.42.4-2.43.50.1-3.6
Epididymis fat weight2.110.814.93.33.02.9-2.83.6-3.63.53.4-3.3-3.3-3.9-3.4-3.53.1-3.33.3-2.1-3.5
Delta time in closed arm before/after self-admin0.20.21.1-0.20.30.1-0.1-0.40.3-0.3-0.30.30.30.90.40.3-0.51.0-0.40.70.0
Delta time in open arm before/after self-admin0.20.30.8-0.6-0.9-0.70.8-0.50.5-0.5-0.50.40.40.00.40.6-0.4-0.1-0.2-0.50.0
Diff in mean of infusions in LGA sessions0.40.60.9-0.8-0.7-0.70.7-0.90.9-0.9-0.70.80.80.90.80.9-0.90.9-0.90.70.0
Delay discount exponential model param0.00.00.20.00.20.1-0.2-0.10.1-0.2-0.1-0.0-0.1-0.3-0.0-0.1-0.40.30.10.10.0
Extinction: sum of active levers before priming1.72.64.5-1.9-2.1-2.02.1-1.81.8-1.8-1.81.61.61.61.61.8-0.80.7-0.31.30.0
Active lever presses in extinction session 63.23.24.8-2.1-2.1-2.22.2-1.81.8-1.9-1.92.02.01.71.92.0-1.61.3-0.01.80.0
Bone: final force2.43.95.3-2.3-2.1-2.32.3-2.22.2-2.2-2.22.12.12.02.12.1-1.41.4-0.22.2-0.0
Bone: final moment2.23.64.9-2.2-2.0-2.22.2-2.12.1-2.1-2.12.12.01.92.02.0-1.41.4-0.12.1-0.0
Food consumed during 24 hour testing period0.10.10.5-0.1-0.1-0.10.0-0.10.1-0.2-0.20.20.3-0.00.30.2-0.70.4-0.70.00.6
Glucose2.64.17.51.81.61.6-1.42.1-2.12.22.0-2.0-2.0-2.0-2.0-2.22.7-2.32.5-1.0-2.4
Heart weight1.22.05.51.01.00.9-0.71.5-1.41.61.2-1.2-1.2-0.8-1.2-1.22.2-1.52.3-0.2-2.3
Delay discount hyperbolic model param0.00.00.30.00.20.1-0.2-0.20.2-0.3-0.1-0.0-0.0-0.2-0.0-0.2-0.50.4-0.10.10.0
Intermittent access intake day 1-15 change0.31.52.91.31.11.2-1.21.3-1.31.21.3-1.4-1.3-1.7-1.4-1.30.8-1.20.9-1.3-0.2
Intermittent access intake escalation0.21.22.51.21.01.1-1.01.2-1.21.01.1-1.3-1.2-1.6-1.2-1.10.6-1.00.8-1.2-0.1
Intermittent access intake escalation 20.61.02.21.10.91.0-1.01.1-1.11.01.0-1.2-1.1-1.5-1.1-1.10.6-1.00.7-1.2-0.1
Intermitt. access day 1 inactive lever presses0.00.31.90.40.30.4-0.40.3-0.40.40.5-0.3-0.4-0.5-0.4-0.40.2-0.4-0.3-1.31.4
Intermitt. access day 15 inactive lever presses0.52.55.01.51.11.2-1.11.5-1.51.61.6-1.6-1.7-2.0-1.6-1.61.6-2.01.8-2.2-0.7
Intermitt. access escalation Index1.23.94.92.11.92.0-1.92.2-2.22.22.0-2.0-2.1-1.9-2.0-2.02.0-1.91.1-1.6-2.1
Intermittent access day 1 total infusions1.64.613.41.61.11.1-0.92.1-2.12.11.7-1.9-1.9-2.2-1.8-1.92.9-2.93.7-1.8-3.0
Intermittent access day 15 total infusions3.17.511.42.62.22.2-2.12.9-2.92.82.7-2.9-2.8-3.3-2.8-2.82.8-3.13.4-2.6-2.2
Intermittent access terminal intake (last 3 days)3.86.614.22.21.81.8-1.62.6-2.62.52.4-2.6-2.5-3.0-2.5-2.52.8-3.13.8-2.2-2.8
Intermittent access total infusions4.55.413.71.91.51.5-1.32.3-2.32.32.0-2.3-2.2-2.6-2.2-2.22.8-2.93.7-1.9-2.7
Intermittent access day 1 locomotion1.73.27.51.41.11.1-0.91.9-1.81.81.5-1.6-1.6-1.9-1.6-1.72.3-2.32.7-1.7-1.8
Intermittent access day 15 total locomotion1.66.09.82.21.61.8-1.62.5-2.42.42.4-2.6-2.5-3.1-2.5-2.42.6-3.13.1-2.7-2.0
Intermittent access total locomotion7.69.118.32.61.82.0-1.73.0-2.93.02.8-2.9-2.9-3.6-2.9-2.93.6-4.04.3-3.0-3.3
Intermittent access standard deviation0.41.93.11.51.41.4-1.41.6-1.61.51.4-1.4-1.4-1.7-1.4-1.40.9-1.11.0-1.80.3
Left kidney weight0.43.15.71.51.11.2-1.12.0-2.02.01.6-1.7-1.6-1.6-1.8-1.42.1-2.12.1-1.8-2.4
Right kidney weight0.21.31.91.11.11.0-1.01.4-1.41.31.1-1.2-1.1-1.2-1.2-1.11.0-1.01.2-1.0-1.3
Cocaine induced anxiety0.00.10.2-0.3-0.4-0.40.4-0.20.2-0.2-0.10.10.10.10.10.2-0.1-0.10.0-0.50.5
Post-drug Anxiety0.80.92.0-1.0-1.0-1.01.0-1.21.2-1.1-0.90.90.90.80.90.7-0.70.6-0.31.40.4
Baseline Anxiety0.40.62.9-0.5-0.2-0.30.3-0.80.8-0.8-0.80.70.70.90.70.6-0.81.1-0.91.70.6
Tail length0.42.25.6-1.1-0.7-0.80.6-1.11.0-1.2-1.31.41.41.71.41.4-2.02.2-2.30.42.4
Length with tail1.98.511.8-2.9-2.3-2.62.4-2.92.9-3.0-3.13.13.03.33.13.0-3.23.4-2.52.92.4
Length without tail1.36.912.3-2.5-1.8-2.12.0-2.72.7-2.7-2.72.62.73.02.82.6-2.93.3-2.13.51.6
Times rat made contact with spout0.50.51.2-0.7-0.7-0.60.6-0.60.6-0.6-0.70.70.71.00.80.8-0.60.7-1.1-0.00.9
Lifetime Intake3.24.010.71.61.41.3-1.12.0-2.02.01.7-1.9-1.8-2.2-1.8-1.92.4-2.43.3-1.5-2.4
Liver weight, left0.81.32.51.31.61.4-1.41.3-1.31.31.2-1.2-1.2-1.0-1.2-1.20.9-0.50.90.1-1.1
Liver weight, right2.13.66.52.22.52.3-2.32.1-2.12.22.1-2.1-2.1-1.6-2.0-2.01.5-1.01.4-0.6-0.8
Locomotor activity2.03.17.02.22.62.5-2.51.8-1.81.82.0-1.9-1.9-1.5-1.8-2.00.7-0.30.1-0.90.0
Locomotor testing distance1.64.09.42.53.12.8-2.92.1-2.12.12.2-2.0-2.1-1.6-2.1-2.30.8-0.20.0-0.9-0.0
Locomotor testing rearing1.03.67.22.32.72.6-2.62.1-2.12.12.2-1.9-2.0-1.5-1.9-1.90.9-0.50.1-1.30.1
Locomotion in novel chamber4.76.39.02.62.52.5-2.42.8-2.82.72.6-2.7-2.7-3.0-2.6-2.82.3-2.42.3-1.80.0
Locomotion in novel chamber post-restriction1.44.36.62.21.82.0-1.92.3-2.32.22.2-2.2-2.2-2.4-2.1-2.01.9-2.21.6-2.60.0
Fecal boli incidents, locomotor time 10.00.10.5-0.2-0.6-0.50.5-0.10.1-0.1-0.10.10.1-0.30.00.30.0-0.70.50.30.0
Change in fecal boli incidents, locomotor task0.10.10.20.10.50.3-0.3-0.10.1-0.00.1-0.0-0.10.2-0.0-0.40.30.40.50.50.0
Time >=10cm from walls, locomotor time 11.01.27.40.4-0.1-0.00.20.7-0.70.80.6-0.8-0.7-1.2-0.8-0.71.8-2.12.7-0.80.0
Bouts of movement, locomotor time 11.62.15.9-1.3-1.6-1.31.2-1.51.4-1.5-1.41.61.41.21.81.2-1.71.3-2.40.20.0
Total resting periods, locomotor time 11.11.33.5-1.1-1.4-1.11.1-1.21.2-1.2-1.11.31.10.91.41.0-1.20.8-1.9-0.10.0
Rest time, locomotor task time 10.91.52.31.41.41.3-1.31.4-1.41.31.3-1.2-1.3-1.5-1.1-1.50.9-1.00.9-0.90.0
Distance moved, locomotor task time 10.10.20.4-0.5-0.6-0.60.6-0.30.3-0.2-0.40.30.30.30.10.50.4-0.20.50.40.0
Vertical activity count, locomotor time 10.11.01.41.21.11.1-1.11.0-1.01.11.1-1.2-1.1-1.1-1.2-1.01.0-0.90.6-0.40.0
Time >=10cm from walls, locomotor time 20.00.10.5-0.4-0.7-0.60.6-0.10.1-0.2-0.30.30.4-0.20.30.2-0.0-0.40.0-0.40.0
Bouts of movement, locomotor time 20.20.61.4-0.8-1.0-0.80.8-0.80.8-0.9-0.70.70.70.70.90.7-0.70.4-1.2-0.00.0
Total resting periods, locomotor time 20.10.20.6-0.5-0.8-0.50.6-0.50.5-0.6-0.40.40.40.30.60.4-0.30.0-0.7-0.40.0
Rest time, locomotor task time 21.72.94.51.71.61.6-1.51.9-1.91.91.8-1.6-1.7-1.8-1.5-2.11.6-1.61.5-2.10.0
Distance moved, locomotor task time 21.11.52.1-1.2-1.1-1.11.0-1.21.2-1.2-1.31.21.31.31.21.3-1.31.3-1.41.30.0
Vertical activity count, locomotor time 20.10.31.50.30.70.6-0.7-0.0-0.0-0.10.1-0.1-0.10.2-0.10.1-0.81.1-1.21.10.0
Light reinforcement 10.00.21.00.40.40.5-0.50.3-0.30.30.3-0.4-0.3-0.1-0.4-0.2-0.10.0-0.5-1.00.5
Light reinforcement 20.41.01.80.90.60.7-0.61.1-1.11.01.0-1.0-1.0-1.3-1.0-0.90.8-1.21.1-0.8-1.2
Bone: marrow area1.12.711.40.90.70.6-0.41.2-1.21.31.1-1.3-1.3-1.4-1.4-1.22.3-2.13.30.3-3.4
Bone: maximum diameter0.30.62.2-0.7-0.8-0.90.9-0.50.5-0.6-0.60.50.50.20.50.6-0.30.01.01.5-1.2
Bone: maximum force2.95.69.7-2.8-2.9-3.03.1-2.62.6-2.5-2.62.52.52.12.52.4-1.11.00.62.6-0.8
Bone: maximum moment2.75.18.8-2.7-2.8-2.93.0-2.52.5-2.4-2.52.42.42.12.32.3-1.01.00.62.4-0.8
Mean time between licks in bursts0.10.51.7-0.40.1-0.10.0-0.60.6-0.6-0.50.50.51.10.60.5-0.81.3-0.91.31.0
Mean num. licks in bursts0.10.30.70.60.60.6-0.70.5-0.50.60.6-0.5-0.5-0.3-0.5-0.50.3-0.1-0.3-0.80.4
Cd content in liver1.21.43.11.10.70.9-0.81.1-1.11.11.2-1.2-1.2-1.5-1.2-0.91.1-1.50.9-1.8-1.0
Co content in liver1.61.84.11.61.81.9-2.01.4-1.41.31.4-1.2-1.2-0.8-1.2-1.0-0.00.2-1.4-1.61.2
Cu content in liver0.10.10.70.1-0.3-0.00.10.1-0.10.20.2-0.2-0.2-0.1-0.2-0.10.5-0.6-0.1-0.80.1
Fe content in liver0.20.32.0-0.3-0.0-0.30.2-0.40.4-0.4-0.40.40.40.40.30.5-0.50.80.11.40.1
K content in liver0.50.51.9-0.7-0.7-0.80.8-0.70.7-0.6-0.70.60.60.80.60.7-0.00.30.31.4-0.7
Mg content in liver0.40.40.90.60.60.6-0.60.6-0.60.70.6-0.7-0.7-0.4-0.6-0.60.8-0.60.50.0-1.0
Mn content in liver3.33.74.8-2.1-2.1-2.22.1-2.12.1-2.2-2.12.12.11.82.12.0-1.61.4-0.62.20.4
Na content in liver0.40.51.1-0.6-0.4-0.50.4-0.60.6-0.7-0.70.70.70.80.60.8-1.11.0-0.50.70.5
Rb content in liver2.02.33.21.71.71.7-1.71.6-1.61.71.7-1.6-1.6-1.5-1.6-1.81.5-1.10.6-1.0-0.9
Se content in liver0.20.20.70.30.10.2-0.10.4-0.40.40.4-0.4-0.4-0.7-0.5-0.20.5-0.70.6-0.2-0.9
Sr content in liver2.92.53.6-1.6-1.5-1.51.4-1.61.6-1.7-1.71.71.71.61.71.7-1.91.6-1.50.81.3
Zn content in liver0.30.30.6-0.6-0.7-0.60.6-0.50.5-0.5-0.50.50.50.80.50.8-0.30.3-0.7-0.10.6
Bone: minimum diameter1.12.18.80.70.30.3-0.11.1-1.11.21.0-1.2-1.2-1.2-1.2-1.12.3-2.22.6-0.4-3.0
Time in familiar zone, hab. session 10.30.30.80.50.30.4-0.30.5-0.50.60.5-0.6-0.5-0.6-0.6-0.60.9-0.80.8-0.2-0.9
Time in novel zone, hab. session 10.20.30.80.60.90.8-0.90.4-0.40.30.5-0.3-0.4-0.1-0.3-0.4-0.40.6-0.60.10.5
Total zone transitions, hab. session 10.60.81.4-1.0-1.2-1.11.1-1.01.0-0.9-1.01.01.00.90.90.9-0.50.4-0.60.10.6
Total locomotion distance, hab. session 10.30.51.20.40.30.3-0.20.6-0.60.70.6-0.6-0.5-0.7-0.6-0.71.1-1.01.1-0.2-1.0
Locomotion velocity, hab. session 10.10.10.4-0.1-0.2-0.20.20.1-0.10.20.1-0.1-0.1-0.2-0.1-0.20.6-0.60.6-0.1-0.5
Time in familiar zone, hab. session 20.20.20.90.30.70.5-0.6-0.00.0-0.00.1-0.2-0.30.4-0.20.1-0.40.8-0.31.00.4
Time in novel zone, hab. session 20.10.20.6-0.4-0.7-0.50.6-0.20.2-0.1-0.20.40.4-0.00.30.10.2-0.40.0-0.8-0.1
Total zone transitions, hab. session 21.31.63.3-1.6-1.8-1.71.8-1.31.3-1.1-1.41.41.41.41.31.2-0.00.20.21.0-0.4
Total locomotion distance, hab. session 20.20.31.5-0.2-0.3-0.40.50.1-0.10.2-0.00.00.00.1-0.0-0.11.0-0.71.20.3-1.2
Locomotion velocity, hab. session 20.40.52.4-0.1-0.2-0.30.40.3-0.30.40.2-0.2-0.2-0.2-0.2-0.31.3-1.01.60.1-1.6
Novel to familiar place preference ratio0.91.22.9-1.3-1.7-1.51.6-1.11.1-1.2-1.21.21.20.61.21.2-0.60.1-0.1-0.00.3
Novelty place preference0.40.61.7-0.9-1.3-1.11.2-0.70.7-0.8-0.80.80.80.20.70.8-0.3-0.20.0-0.50.2
Time in novel zone, NPP test0.30.41.2-0.8-1.1-0.91.0-0.60.6-0.6-0.60.70.70.20.60.7-0.2-0.10.0-0.40.1
Total zone transitions, NPP test2.13.14.8-2.1-2.2-2.22.2-1.91.9-1.8-2.02.02.01.91.91.9-1.01.0-0.51.10.3
Total locomotion distance, NPP test0.10.10.4-0.4-0.5-0.50.5-0.20.2-0.1-0.30.30.30.20.20.10.5-0.30.50.2-0.6
Locomotion velocity, NPP test0.10.20.4-0.5-0.6-0.60.6-0.30.3-0.2-0.40.40.40.20.30.20.4-0.30.4-0.1-0.4
Intraocular pressure0.71.22.71.21.01.2-1.21.2-1.21.01.2-1.1-1.1-1.6-1.3-1.10.3-0.90.3-1.50.3
Delta distance traveled before/after self-admin0.30.31.10.60.90.8-0.90.2-0.30.20.5-0.4-0.4-0.1-0.4-0.5-0.30.5-1.1-0.40.0
Delta ambulatory time before/after self-admin0.10.21.20.40.70.6-0.70.1-0.10.00.3-0.2-0.20.1-0.2-0.3-0.50.7-1.1-0.10.0
Parametrial fat weight3.58.311.22.72.22.3-2.13.0-3.03.02.8-3.0-3.0-3.2-3.0-2.83.3-3.33.2-2.4-3.0
Pavlov. Cond. lever latency0.20.30.70.70.80.8-0.80.6-0.60.50.7-0.5-0.6-0.6-0.6-0.60.0-0.1-0.3-0.40.3
Pavlov. Cond. magazine entry latency0.40.51.5-0.8-1.2-1.11.1-0.50.5-0.4-0.60.50.60.50.60.70.3-0.40.5-0.4-0.5
Pavlov. Cond. change in total contacts0.30.31.1-0.5-1.1-0.80.9-0.30.3-0.3-0.30.20.30.00.40.40.3-0.80.4-1.0-0.4
Pavlov. Cond. index score0.20.30.8-0.7-0.9-0.80.8-0.50.5-0.5-0.60.50.50.50.60.6-0.2-0.0-0.0-0.3-0.1
Pavlov. Cond. latency score0.20.20.6-0.6-0.7-0.70.7-0.30.3-0.4-0.50.40.40.40.50.50.1-0.10.2-0.2-0.3
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.5-0.50.6-0.30.3-0.2-0.40.20.30.40.30.30.2-0.10.50.2-0.6
Pavlov. Cond. magazine entry number0.40.41.10.71.00.9-0.90.7-0.60.70.7-0.6-0.6-0.5-0.7-0.80.5-0.10.40.7-0.4
Pavlov. Cond. intertrial magazine entries0.60.71.41.00.80.9-0.90.8-0.80.70.8-0.9-1.0-1.1-0.9-0.80.4-0.7-0.0-1.2-0.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.4-0.9-1.2-1.11.1-0.70.7-0.7-0.80.70.70.70.80.8-0.2-0.00.0-0.3-0.1
Pavlov. Cond. response bias0.20.30.7-0.6-0.9-0.70.7-0.50.5-0.6-0.60.50.50.40.60.6-0.30.0-0.2-0.50.2
Pavlov. Cond. lever latency0.60.81.31.01.11.1-1.10.9-0.91.01.0-1.0-1.0-0.6-1.0-0.90.7-0.4-0.2-1.00.3
Pavlov. Cond. magazine entry latency3.65.18.1-2.6-2.9-2.72.8-2.42.4-2.4-2.52.42.42.42.42.6-1.61.3-1.01.20.9
Pavlov. Cond. change in total contacts1.02.35.5-1.8-2.3-2.12.2-1.61.6-1.7-1.71.61.61.01.61.6-0.80.1-0.10.50.1
Pavlov. Cond. index score2.03.25.9-2.2-2.4-2.32.4-1.91.9-1.9-2.12.02.01.52.02.0-1.10.7-0.31.20.2
Pavlov. Cond. latency score1.72.75.0-2.0-2.2-2.22.2-1.71.7-1.8-1.91.81.81.41.81.8-0.90.6-0.11.2-0.1
Pavlov. Cond. lever contacts0.50.81.3-1.1-1.1-1.11.2-0.90.9-1.0-1.01.01.00.61.00.9-0.70.40.10.9-0.2
Pavlov. Cond. magazine entry number6.68.613.33.43.63.5-3.53.2-3.23.23.3-3.2-3.2-2.8-3.2-3.22.2-1.81.5-1.6-1.4
Pavlov. Cond. intertrial magazine entries0.61.41.81.31.31.3-1.21.2-1.21.21.3-1.3-1.3-1.3-1.4-1.31.0-0.90.8-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.2.53.97.0-2.4-2.6-2.52.6-2.12.1-2.1-2.32.22.21.72.12.2-1.30.9-0.51.30.4
Pavlov. Cond. response bias2.02.84.7-2.0-2.2-2.12.1-1.71.7-1.8-1.91.91.91.51.91.9-1.20.8-0.41.20.2
Time in closed arm before self-admin0.20.31.20.40.10.2-0.10.5-0.50.50.4-0.5-0.5-0.9-0.6-0.60.9-1.10.9-0.30.0
Time in closed arm after self-admin0.30.30.60.70.80.7-0.70.4-0.40.40.6-0.6-0.6-0.5-0.7-0.70.7-0.50.5-0.10.0
Time in open arm before self-admin0.40.41.30.71.11.0-1.10.6-0.60.60.5-0.4-0.40.3-0.3-0.4-0.00.6-1.00.10.0
Time in open arm after self-admin0.10.21.0-0.2-0.1-0.10.0-0.10.1-0.1-0.30.30.30.50.40.4-0.60.7-1.0-0.30.0
Bone: periosteal estimation0.30.75.2-0.3-0.4-0.60.7-0.10.1-0.0-0.1-0.0-0.1-0.2-0.10.00.8-0.82.11.1-2.3
Bone: periosteal perimeter0.30.62.6-0.7-0.7-0.90.9-0.40.4-0.4-0.50.40.40.10.40.40.3-0.41.41.3-1.6
Bone: post-yield work1.72.911.0-1.5-2.3-2.22.5-0.90.9-0.7-1.00.80.80.10.80.61.8-2.03.00.7-3.3
Progressive ratio test 1 active lever presses0.30.51.30.50.40.4-0.30.8-0.80.70.5-0.6-0.6-0.8-0.6-0.60.7-0.81.1-0.9-0.7
Progressive ratio test 1 breakpoint0.20.41.20.40.30.3-0.20.7-0.70.60.5-0.5-0.5-0.8-0.5-0.50.6-0.71.1-0.8-0.7
Progressive ratio test 1 inactive lever presses0.10.21.40.30.10.2-0.20.3-0.40.30.3-0.3-0.3-0.5-0.3-0.20.2-0.40.0-1.20.8
Progressive ratio test 2 active lever presses2.23.15.11.61.31.3-1.21.9-1.91.81.6-1.9-1.8-2.2-1.8-1.81.7-2.12.3-1.9-1.4
Progressive ratio test 2 breakpoint2.43.04.91.61.31.4-1.21.9-1.91.81.6-1.8-1.7-2.2-1.8-1.81.7-2.02.2-1.8-1.3
Progressive ratio test 2 inactive lever presses3.210.214.83.22.62.8-2.73.3-3.33.33.2-3.4-3.3-3.8-3.3-3.33.1-3.63.0-3.5-2.0
Incentive Sensitization - Responses0.10.21.7-0.1-0.3-0.30.40.1-0.10.1-0.1-0.2-0.1-0.4-0.1-0.10.6-0.71.30.0-1.0
Incentive Sensitization - Breakpoint0.10.32.00.2-0.0-0.00.10.4-0.30.30.1-0.5-0.3-0.6-0.4-0.40.8-0.91.4-0.2-1.0
Sum of active levers in priming session hrs 5-61.21.13.1-1.0-1.0-1.01.0-1.21.2-1.4-1.01.01.00.50.91.0-1.81.0-0.71.10.0
Progressive ratio0.51.64.2-1.6-1.9-1.92.0-1.11.1-0.9-1.31.21.21.11.41.30.4-0.31.10.80.0
Food seeking constrained by brief footshock0.10.10.3-0.10.0-0.00.0-0.40.4-0.3-0.10.20.20.40.20.2-0.20.4-0.30.50.0
Seeking ratio, punishment vs. effort0.92.05.31.92.22.2-2.31.3-1.31.21.6-1.4-1.4-1.1-1.6-1.50.10.1-0.8-0.70.0
Retroperitoneal fat weight8.939.747.36.86.66.5-6.36.9-6.96.96.8-6.7-6.7-6.7-6.7-6.85.9-5.44.7-4.9-4.4
Reaction time number correct0.10.41.3-0.5-0.2-0.40.3-0.40.4-0.5-0.60.80.80.50.60.5-1.01.1-0.60.90.7
Reaction time mean minus median0.74.78.0-2.6-2.8-2.72.7-2.42.4-2.3-2.32.32.21.82.52.3-1.61.1-0.71.71.1
Reaction time mean minus median AUC0.42.43.4-1.8-1.8-1.81.8-1.71.7-1.7-1.61.71.61.31.81.6-1.41.1-0.71.31.3
Reaction time num false alarms0.30.61.81.01.31.2-1.30.6-0.60.60.6-0.8-0.8-0.3-0.8-0.90.30.3-0.40.10.3
Reaction time num false alarms AUC0.10.20.60.30.70.5-0.6-0.00.0-0.0-0.0-0.1-0.10.3-0.1-0.2-0.20.7-0.80.50.8
Reaction time trials correct on left0.10.41.3-0.5-0.2-0.40.3-0.40.4-0.5-0.60.80.80.50.60.5-1.01.1-0.60.90.7
Reaction time trials on left0.20.61.6-0.6-0.2-0.40.3-0.50.5-0.6-0.70.90.90.60.70.5-1.11.3-0.71.00.8
Reaction time mean0.10.20.6-0.4-0.8-0.50.6-0.30.3-0.4-0.40.40.2-0.20.40.1-0.1-0.3-0.3-0.30.4
Reaction time mean AUC0.10.10.6-0.3-0.8-0.50.6-0.30.3-0.3-0.30.30.1-0.30.30.00.1-0.5-0.2-0.40.4
Median of all reaction times0.10.20.70.2-0.20.1-0.00.3-0.30.30.2-0.2-0.4-0.7-0.3-0.50.5-0.8-0.1-0.80.0
Reaction time omissions1.62.53.4-1.8-1.8-1.81.8-1.81.8-1.7-1.61.81.71.31.81.4-1.31.1-1.11.31.5
Reaction time false alarm rate0.30.41.00.81.00.9-1.00.5-0.50.50.6-0.8-0.8-0.2-0.7-0.70.5-0.1-0.10.00.0
Reaction time premature initiation rate2.43.76.5-1.8-1.2-1.41.3-2.01.9-1.9-2.01.91.92.42.11.9-2.12.6-1.92.41.4
Reaction time premature initiations2.06.011.0-2.2-1.6-1.81.6-2.42.4-2.4-2.52.52.62.82.62.3-2.93.3-2.62.72.3
Std. dev. reaction times0.41.52.8-1.4-1.7-1.51.6-1.41.4-1.3-1.31.31.30.81.41.1-0.90.5-0.60.81.0
Reaction time trials completed0.20.61.6-0.6-0.2-0.40.3-0.50.5-0.6-0.70.90.90.60.70.5-1.11.3-0.71.00.8
Reaction time trials AUC0.10.31.2-0.4-0.0-0.20.2-0.40.4-0.5-0.50.70.70.50.50.4-0.91.1-0.50.90.6
Run reversals in cocaine runway, females0.30.30.9-0.5-0.5-0.60.6-0.50.5-0.3-0.60.60.60.90.40.60.40.10.70.70.0
Run reversals in cocaine runway, males0.40.41.30.81.21.0-1.10.6-0.60.50.7-0.6-0.6-0.6-0.6-0.4-0.40.4-0.3-0.40.0
Latency to leave start box in cocaine runway0.20.31.40.1-0.2-0.10.20.2-0.20.30.3-0.4-0.4-0.3-0.4-0.21.1-1.11.2-0.40.0
Latency to leave start box in cocaine runway, F0.10.11.00.0-0.3-0.10.20.2-0.20.30.2-0.1-0.1-0.0-0.20.00.7-0.80.4-1.00.0
Latency to leave start box in cocaine runway, M0.20.21.3-0.1-0.0-0.20.3-0.20.2-0.2-0.0-0.1-0.1-0.1-0.1-0.10.4-0.31.21.10.0
Std. dev. time between licks in bursts0.10.20.80.40.90.6-0.70.2-0.20.10.2-0.2-0.20.3-0.1-0.2-0.40.9-0.50.90.3
Total sessions with >9 infusions0.30.32.3-0.1-0.2-0.30.40.2-0.20.2-0.1-0.1-0.0-0.2-0.0-0.20.8-0.71.50.2-1.5
Short access day 1 total inactive lever presses1.52.93.81.91.81.8-1.71.6-1.61.71.7-1.7-1.8-2.0-1.8-1.91.8-1.71.7-1.4-0.5
Short access day 10 total inactive lever presses0.10.81.91.01.01.1-1.10.7-0.80.80.9-0.8-0.9-0.7-0.9-0.80.6-0.5-0.0-1.11.4
Short access day 1 total infusions1.22.45.81.31.11.1-0.91.5-1.51.61.3-1.4-1.5-1.5-1.4-1.52.0-1.92.4-1.2-1.8
Short access day 10 total infusions1.01.68.70.40.00.00.20.9-0.90.90.6-0.7-0.7-1.0-0.7-0.82.1-2.03.0-0.9-2.2
Short access total infusions0.81.26.60.60.50.3-0.20.9-0.90.90.6-0.8-0.7-0.9-0.7-0.91.7-1.52.6-0.3-1.8
Short access day 1 locomotion1.32.23.41.41.21.2-1.11.5-1.51.51.4-1.6-1.5-1.6-1.5-1.51.8-1.81.8-1.4-1.4
Short access day 10 total locomotion0.41.74.40.90.50.6-0.51.3-1.31.31.1-1.0-1.1-1.4-1.2-1.11.7-1.92.1-1.4-1.3
Short access total locomotion1.42.24.81.20.90.9-0.81.5-1.51.51.3-1.3-1.4-1.6-1.4-1.41.9-2.02.2-1.4-1.7
One hour access (0.3 mA shock)6.88.110.43.02.72.7-2.63.1-3.13.02.9-3.0-3.0-3.2-3.0-2.92.6-2.72.7-2.7-1.8
Compulsive drug intake1.92.88.2-1.2-0.6-0.70.5-1.51.5-1.5-1.41.61.52.11.51.6-2.12.5-2.91.91.6
One hour access (shock baseline)3.79.814.13.02.52.6-2.43.3-3.33.33.1-3.3-3.2-3.8-3.2-3.23.1-3.53.5-3.3-2.2
Social response proportion0.60.81.3-1.0-1.1-1.01.0-1.11.1-1.1-1.00.80.90.80.90.9-0.80.5-0.40.90.5
Social responses0.30.40.9-0.5-0.3-0.40.3-0.60.6-0.6-0.50.50.50.60.60.6-0.80.8-0.80.70.9
Social time0.40.61.5-0.6-0.3-0.40.4-0.60.6-0.6-0.60.90.90.70.80.6-1.11.2-0.90.61.2
Soleus weight4.112.014.73.83.73.7-3.63.8-3.83.83.8-3.7-3.7-3.6-3.8-3.83.0-2.82.1-2.7-2.4
Bone: stiffness2.24.07.5-2.4-2.7-2.72.7-2.22.2-2.1-2.22.12.11.72.12.0-0.90.60.31.8-0.6
Tibialis anterior weight10.034.341.5-6.3-5.6-6.05.8-6.36.3-6.3-6.36.46.46.16.46.3-5.75.5-3.35.53.6
Time to tail flick, vehicle, before self-admin0.20.30.7-0.6-0.7-0.70.8-0.30.3-0.3-0.50.50.50.40.50.40.1-0.10.60.80.0
Time to tail flick, vehicle, after self-admin0.30.71.6-1.0-1.1-1.21.3-0.60.6-0.4-0.80.80.81.10.81.00.40.01.00.80.0
Time to tail flick, test, before self-admin1.92.24.51.41.31.3-1.21.6-1.51.61.4-1.5-1.5-1.4-1.5-1.52.1-1.82.0-0.90.0
Time to tail flick, test, after self-admin0.10.10.1-0.3-0.3-0.40.4-0.20.2-0.3-0.20.30.30.00.20.3-0.30.10.20.30.0
Delta time to tail flick, vehicle, before/after SA0.30.30.6-0.7-0.6-0.70.7-0.60.6-0.5-0.50.60.60.80.60.7-0.00.30.20.40.0
Delta time to tail flick, test, before/after SA1.82.26.3-1.3-1.1-1.11.0-1.41.4-1.6-1.31.51.51.21.51.5-2.52.0-2.30.80.0
Tibia length1.02.74.2-1.9-2.0-2.12.0-1.81.8-1.9-1.81.71.81.11.61.8-1.60.8-0.21.3-0.2
Ambulatory time before self-admin0.20.61.8-0.9-1.4-1.21.3-0.70.8-0.7-0.80.70.70.30.70.9-0.0-0.40.50.30.0
Ambulatory time after self-admin0.20.31.20.3-0.10.1-0.10.3-0.30.30.4-0.4-0.4-0.7-0.4-0.40.7-1.00.3-1.10.0
Bone: tissue strength0.00.00.0-0.1-0.2-0.10.2-0.20.2-0.1-0.10.00.0-0.20.0-0.10.2-0.20.2-0.1-0.1
Total heroin consumption5.36.27.8-2.8-2.8-2.72.7-2.72.7-2.7-2.72.72.72.72.72.8-2.22.0-1.72.20.0
Bone: trabecular number0.71.33.0-1.4-1.7-1.61.7-1.21.2-1.1-1.21.01.10.81.01.10.0-0.20.80.9-1.1
Bone: trabecular spacing0.50.71.30.91.11.1-1.10.9-1.00.90.8-0.7-0.7-0.5-0.7-0.90.30.0-0.5-1.00.8
Bone: trabecular thickness0.40.61.30.50.30.4-0.30.5-0.50.60.6-0.7-0.6-0.8-0.7-0.71.1-1.11.1-0.6-1.1
Bone: trabecular tissue density3.25.67.22.72.52.6-2.62.6-2.62.62.7-2.6-2.7-2.6-2.6-2.41.8-1.91.1-2.1-1.0
Water consumed over 24 hours0.81.53.2-1.1-1.1-1.00.9-1.11.1-1.2-1.21.31.31.41.31.3-1.41.3-1.80.21.5
Number of responses in last shaping day0.10.10.70.20.40.3-0.40.2-0.20.10.1-0.1-0.10.1-0.0-0.1-0.30.4-0.6-0.40.8