Tm7sf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Tm7sf2 0.24 0.1 8.0e-15 0.24 0.26 0.25 0.26 3.1e-13 3.9e-14 1.0e-13 5.7e-14
2 IL gene expression Tm7sf2 0.18 0.12 1.9e-03 0.11 0.12 0.06 0.09 1.6e-03 9.8e-04 1.9e-02 3.4e-03
3 Liver isoform ratio NM_001013071.1 0.03 0.02 2.5e-03 0.01 0.01 0.01 0.01 8.4e-03 6.7e-03 5.5e-02 1.7e-02
4 Liver isoform ratio XM_039108440.2 0.03 0.02 1.4e-03 0.01 0.02 0.01 0.01 2.0e-02 5.1e-03 3.4e-02 1.3e-02
5 Liver gene expression Tm7sf2 0.2 0.1 1.1e-15 0.1 0.1 0.1 0.11 7.8e-11 2.2e-11 1.1e-10 3.7e-12
6 OFC gene expression Tm7sf2 0.23 0.11 2.7e-05 0.23 0.2 0.21 0.22 4.2e-06 1.3e-05 9.1e-06 7.5e-06
7 Brain gene expression Tm7sf2 0.28 0.11 0.0e+00 0.27 0.26 0.27 0.27 4.4e-25 3.7e-24 6.7e-25 2.7e-25
8 pVTA gene expression Tm7sf2 0.3 0.11 0.0e+00 0.33 0.32 0.33 0.33 6.8e-27 7.9e-26 1.3e-27 1.3e-27
9 NAcc gene expression Tm7sf2 0.12 0.06 0.0e+00 0.16 0.14 0.16 0.16 1.0e-23 2.9e-21 5.9e-23 3.8e-23
10 IC gene expression Tm7sf2 0.27 0.11 3.1e-11 0.17 0.1 0.16 0.17 7.8e-08 4.8e-05 4.2e-07 1.3e-07
11 NAcc mRNA stability Tm7sf2 0.04 0.03 1.0e-07 0.05 0.05 0.06 0.05 2.2e-08 2.3e-08 1.0e-08 1.7e-08
12 Brain mRNA stability Tm7sf2 0.05 0.03 1.1e-04 0.04 0.04 0.03 0.03 1.9e-04 2.5e-04 3.7e-04 3.4e-04
13 PL gene expression Tm7sf2 0.21 0.13 0.0e+00 0.22 0.2 0.21 0.21 1.4e-23 6.2e-21 5.2e-23 1.0e-22
14 Adipose gene expression Tm7sf2 0.17 0.07 2.2e-16 0.07 0.1 0.08 0.1 1.1e-08 1.7e-11 6.5e-09 9.0e-11
15 IC mRNA stability Tm7sf2 0.07 0.05 7.0e-03 0.01 0.01 0.02 0.01 1.3e-01 1.0e-01 4.5e-02 1.7e-01
16 PL mRNA stability Tm7sf2 0.05 0.03 1.1e-05 0.04 0.05 0.05 0.05 9.9e-05 5.1e-06 5.3e-06 3.2e-06
17 LHb gene expression Tm7sf2 0.23 0.13 1.9e-04 0.13 0.15 0.17 0.12 6.9e-04 2.3e-04 8.5e-05 9.0e-04
18 Adipose mRNA stability Tm7sf2 0.04 0.03 3.4e-04 0.02 0.02 0.02 0.02 2.5e-03 2.9e-03 3.4e-03 3.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.50.92.0-1.1-1.3-1.31.4-0.9-0.9-0.8-1.0-0.8-0.9-0.8-0.7-0.90.30.31.0-0.81.2
Area under the delay curve0.10.10.40.0-0.2-0.10.10.20.20.30.10.00.0-0.20.0-0.10.60.50.10.30.0
BMI with tail1.86.213.3-3.0-3.3-3.43.6-2.5-2.5-2.2-2.6-2.3-2.4-2.3-2.3-2.30.60.22.2-2.82.1
BMI without tail0.72.04.1-1.8-1.9-1.92.0-1.4-1.4-1.3-1.6-1.5-1.5-1.7-1.4-1.40.1-0.20.5-1.00.5
Body weight2.711.717.0-4.0-3.8-4.14.1-3.7-3.7-3.6-3.9-3.7-3.7-3.7-3.7-3.6-1.9-2.2-0.1-4.00.0
Weight adjusted by age1.21.92.4-1.5-1.4-1.41.4-1.4-1.4-1.4-1.3-1.5-1.5-1.4-1.5-1.4-1.5-1.4-1.0-1.30.0
Bone surface4.58.213.8-3.4-3.6-3.63.7-3.2-3.2-3.1-3.2-3.0-3.1-2.6-3.0-3.1-1.6-1.30.3-2.80.6
Bone volume1.73.06.4-2.1-2.4-2.42.5-1.8-1.8-1.7-1.9-1.7-1.8-1.3-1.7-1.8-0.4-0.11.0-1.41.1
Breakpoint value in progressive ratio session3.03.65.4-2.2-2.3-2.22.2-2.2-2.2-2.2-2.1-2.0-2.0-1.8-1.9-2.1-1.5-1.2-0.9-1.50.0
Number of licking bursts0.20.40.6-0.7-0.8-0.70.7-0.6-0.6-0.7-0.7-0.6-0.6-0.5-0.7-0.6-0.4-0.3-0.2-0.5-0.1
Context. condit. distance diff. score1.92.32.91.71.61.6-1.61.71.71.71.71.71.61.41.71.51.51.30.91.31.0
Locomotion velocity, session 10.10.10.40.00.40.2-0.30.00.00.00.0-0.1-0.1-0.4-0.1-0.1-0.4-0.6-0.4-0.3-0.5
Locomotion distance, session 10.40.50.9-0.9-0.8-0.90.9-0.7-0.7-0.6-0.7-0.8-0.8-0.9-0.7-0.60.1-0.20.4-1.00.4
Locomotion velocity, session 22.63.04.2-2.0-1.9-2.02.0-1.8-1.8-1.8-1.9-1.9-1.9-2.0-1.8-1.9-1.0-1.1-0.3-1.90.0
Locomotion distance, session 20.60.81.3-1.1-1.0-1.01.1-1.0-1.0-0.8-1.0-1.0-1.0-1.2-0.9-0.8-0.2-0.5-0.1-1.1-0.1
Locomotion velocity, session 30.50.52.50.30.40.2-0.10.30.30.50.40.40.40.50.50.71.10.71.5-0.91.6
Locomotion distance, session 30.00.00.10.20.20.2-0.20.00.00.10.20.20.20.20.20.20.20.10.1-0.20.2
Stereotopy head waving bouts, day 30.81.03.10.70.80.6-0.60.90.91.00.80.80.90.70.81.11.40.91.8-0.61.5
Stereotopy head waving duration, day 30.80.91.90.80.80.7-0.61.01.01.10.90.90.90.90.91.11.21.01.40.31.2
Locomotion velocity, session 70.70.82.80.40.10.2-0.00.70.60.80.60.60.60.80.70.81.61.41.5-0.01.7
Locomotion distance, session 70.10.10.50.10.20.1-0.10.00.00.1-0.00.20.20.00.20.40.60.30.5-0.70.6
Stereotopy head waving bouts, day 70.20.20.8-0.1-0.4-0.30.40.20.20.20.10.20.10.30.10.00.60.90.90.20.9
Stereotopy head waving duration, day 70.70.82.2-1.1-1.5-1.31.4-0.8-0.8-0.7-0.8-0.9-1.0-0.7-1.0-1.0-0.10.20.2-0.30.2
Locomotion velocity, session 81.01.23.6-0.9-0.4-0.70.6-1.1-1.1-1.2-1.1-1.1-1.0-1.4-1.0-1.1-1.3-1.6-0.9-1.9-0.7
Locomotion distance, session 80.40.51.90.40.40.3-0.20.60.60.70.50.50.50.50.60.61.10.91.3-0.21.4
Degree of sensitization distance0.20.21.0-0.1-0.0-0.20.20.00.00.0-0.20.0-0.0-0.00.10.30.60.31.0-0.80.8
Degree of sensitization stereotypy0.50.51.5-0.8-1.2-1.11.1-0.7-0.7-0.7-0.6-0.6-0.7-0.4-0.7-0.8-0.10.30.2-0.10.3
Conditioned locomotion1.61.82.6-1.5-1.2-1.41.3-1.4-1.4-1.4-1.4-1.5-1.4-1.4-1.6-1.3-1.3-1.4-0.7-1.6-0.7
Cocaine response after cond. corrected1.31.62.71.41.61.5-1.51.51.51.51.41.31.41.11.31.51.10.60.70.10.6
Cocaine response after cond. not corrected1.01.22.01.21.41.3-1.31.21.21.21.21.11.20.91.21.21.00.60.7-0.20.7
Cocaine response before conditioning0.70.91.5-1.0-1.2-1.11.1-1.1-1.1-1.1-1.0-0.9-1.0-0.8-0.9-1.1-0.7-0.4-0.4-0.6-0.4
Saline control response4.35.79.0-2.4-2.1-2.32.2-2.5-2.5-2.5-2.5-2.5-2.5-2.7-2.6-2.6-2.2-2.4-1.4-3.0-1.4
Bone: connectivity density2.33.66.2-2.3-2.4-2.42.5-2.2-2.2-2.0-2.1-1.9-2.0-1.9-1.9-2.1-0.7-0.70.3-2.00.6
Bone: cortical apparent density0.20.31.7-0.1-0.2-0.10.0-0.4-0.3-0.4-0.2-0.3-0.3-0.2-0.3-0.3-0.6-0.4-1.30.9-1.3
Bone: cortical area0.71.12.1-1.2-1.1-1.21.2-1.1-1.1-1.1-1.1-1.1-1.1-0.9-1.1-1.1-0.9-0.70.1-1.40.3
Bone: cortical porosity0.10.20.4-0.5-0.6-0.60.6-0.3-0.3-0.3-0.5-0.4-0.5-0.4-0.5-0.3-0.1-0.1-0.1-0.00.2
Bone: cortical porosity0.50.60.9-1.0-1.0-1.01.0-0.7-0.7-0.7-0.9-0.8-0.9-0.9-0.9-0.7-0.4-0.5-0.2-0.50.0
Bone: cortical thickness2.94.87.1-2.0-1.6-1.71.5-2.2-2.2-2.3-2.2-2.3-2.3-2.4-2.2-2.3-2.7-2.6-2.4-1.8-2.2
Bone: cortical thickness0.70.82.3-0.4-0.1-0.20.0-0.7-0.7-0.8-0.7-0.7-0.7-1.1-0.7-0.7-1.2-1.5-1.5-0.7-1.4
Bone: cortical tissue density0.30.52.2-0.3-0.4-0.20.1-0.5-0.5-0.6-0.4-0.5-0.5-0.4-0.5-0.4-0.8-0.6-1.40.8-1.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.4-0.5-0.40.5-0.3-0.3-0.3-0.3-0.4-0.4-0.4-0.4-0.3-0.0-0.1-0.20.2-0.2
Condit. Reinf. active-inactive response ratio0.10.10.9-0.1-0.3-0.10.10.00.10.0-0.0-0.2-0.1-0.1-0.2-0.1-0.1-0.1-0.71.0-0.7
Condit. Reinf. active responses0.10.10.4-0.2-0.4-0.30.4-0.1-0.1-0.1-0.1-0.1-0.10.0-0.10.00.50.40.6-0.00.6
Condit. Reinf. inactive responses0.40.52.70.10.0-0.10.20.20.10.20.20.40.30.50.30.41.00.91.5-0.81.6
Incentive salience index mean0.20.30.7-0.7-0.8-0.80.8-0.5-0.5-0.4-0.6-0.5-0.5-0.6-0.5-0.50.20.00.3-0.20.4
Condit. Reinf. lever presses0.50.71.5-1.0-1.1-1.11.2-0.8-0.8-0.8-1.0-0.7-0.7-0.5-0.7-0.70.00.00.9-0.90.9
Condit. Reinf. active minus inactive responses0.10.10.50.1-0.1-0.00.10.10.10.10.10.20.20.60.30.30.40.70.60.20.7
Condit. Reinf. active-inactive response ratio0.91.13.90.60.40.3-0.20.80.80.80.70.90.81.40.90.91.21.51.90.12.0
Condit. Reinf. active responses0.10.20.6-0.5-0.7-0.60.6-0.5-0.5-0.5-0.4-0.3-0.4-0.1-0.3-0.3-0.00.3-0.10.30.0
Condit. Reinf. inactive responses0.60.71.3-0.8-0.9-0.80.7-1.0-1.0-0.9-0.8-0.9-0.8-1.1-0.8-0.9-0.6-0.7-1.10.2-1.1
Condit. Reinf. lever presses1.82.54.2-1.9-2.0-2.02.0-1.8-1.8-1.8-1.9-1.7-1.7-1.2-1.7-1.6-1.1-0.7-0.1-1.1-0.0
Condit. Reinf. lever reinforcers received0.30.51.1-0.8-1.0-0.90.9-0.9-0.9-0.8-0.8-0.7-0.7-0.4-0.7-0.7-0.4-0.1-0.30.1-0.3
Conditioned reinforcement - actives0.00.10.4-0.2-0.3-0.30.40.10.1-0.1-0.10.1-0.00.4-0.1-0.1-0.30.10.6-0.10.0
Conditioned reinforcement - inactives2.43.56.32.01.61.7-1.71.91.91.82.12.12.12.52.11.81.52.01.52.10.8
Conditioned locomotion7.39.513.23.43.13.3-3.23.33.33.23.33.43.33.63.33.32.42.71.83.30.8
Patch foraging indifference point 0 sec0.00.00.10.10.10.1-0.1-0.1-0.1-0.10.10.30.30.10.20.20.30.30.20.00.0
Patch foraging indifference point AUC2.23.24.2-1.9-2.0-1.91.9-2.0-2.0-2.0-2.0-1.9-2.0-1.5-1.8-1.9-1.8-1.4-1.2-0.7-1.5
Delay disc. indifference point, 0s delay0.30.41.20.40.20.3-0.21.01.01.00.40.40.40.10.40.21.10.80.80.70.0
Delay disc. indifference point, 16s delay0.70.81.80.80.40.6-0.50.70.70.80.90.81.01.10.90.91.21.30.71.30.0
Delay disc. indifference point, 2s delay0.20.20.70.20.10.1-0.00.50.50.50.30.30.30.20.40.10.70.70.8-0.20.0
Delay disc. indifference point, 24s delay0.10.10.30.30.40.4-0.50.20.20.30.30.20.1-0.10.20.1-0.1-0.4-0.60.20.0
Delay disc. indifference point, 4s delay0.10.10.40.30.20.2-0.20.40.40.50.30.20.2-0.20.20.10.60.30.1-0.00.0
Delay disc. indifference point, 8s delay0.00.00.10.10.00.1-0.10.20.20.30.1-0.1-0.0-0.3-0.00.00.30.1-0.20.20.0
Indifference point function ln k6.511.315.33.83.93.8-3.83.63.63.73.83.73.83.23.53.73.02.41.91.82.4
Indifference point function log k6.511.315.33.83.93.8-3.83.63.63.73.83.73.83.23.53.73.02.41.91.82.4
Patch foraging total patch changes 0 sec0.00.00.10.10.20.2-0.2-0.2-0.2-0.2-0.00.20.1-0.10.10.1-0.1-0.2-0.2-0.2-0.4
Patch foraging total patch changes 12 sec4.65.98.0-2.7-2.7-2.62.6-2.8-2.8-2.8-2.8-2.5-2.6-2.5-2.5-2.6-1.9-1.8-1.4-1.3-1.9
Patch foraging total patch changes 18 sec0.50.81.4-1.0-1.2-1.11.2-1.1-1.1-1.0-1.1-1.0-1.0-0.8-0.9-1.0-0.5-0.30.1-0.4-0.3
Patch foraging total patch changes 24 sec1.73.03.7-1.7-1.5-1.51.5-1.9-1.9-1.9-1.9-1.8-1.8-1.8-1.7-1.8-1.9-1.8-1.3-1.6-1.8
Patch foraging total patch changes 6 sec1.01.52.7-1.3-1.1-1.21.1-1.7-1.7-1.5-1.4-1.2-1.2-1.4-1.1-1.2-0.9-1.0-0.5-1.3-0.6
Patch foraging time to switch 0 sec1.32.76.2-2.0-2.4-2.32.5-1.7-1.7-1.5-1.7-1.7-1.7-1.5-1.6-1.7-0.00.10.9-0.90.7
Patch foraging water rate 0 sec2.96.211.33.13.33.3-3.42.72.82.52.72.62.72.62.72.71.00.90.11.60.6
Patch foraging water rate 12 sec6.012.623.04.34.84.6-4.84.04.03.94.13.73.73.33.83.71.71.30.22.20.9
Patch foraging water rate 18 sec2.74.17.82.42.82.6-2.72.42.42.32.32.12.21.82.12.11.20.70.51.00.7
Patch foraging water rate 24 sec4.05.710.22.83.23.0-3.12.82.82.62.72.42.52.32.52.61.20.90.61.11.1
Patch foraging water rate 6 sec4.26.213.23.13.63.4-3.52.72.72.62.82.52.62.22.62.81.10.50.20.80.8
Seeking ratio, delayed vs. immediate footshock0.10.20.70.40.00.2-0.10.10.10.20.30.50.50.40.20.50.90.80.10.20.0
Distance traveled before self-admin0.60.82.1-1.1-1.5-1.31.4-0.9-0.9-0.9-1.0-0.9-0.9-0.7-1.0-1.1-0.20.10.3-0.40.0
Distance traveled after self-admin0.20.30.6-0.6-0.8-0.60.6-0.6-0.6-0.7-0.5-0.5-0.5-0.4-0.5-0.6-0.5-0.2-0.70.20.0
Extensor digitorum longus weight7.328.936.6-6.0-5.7-5.95.8-5.8-5.8-5.7-5.9-5.9-5.9-5.8-5.9-5.8-4.3-4.4-2.4-5.0-2.4
Bone: elastic displacement1.11.23.41.41.81.7-1.81.11.11.01.11.01.00.71.01.1-0.1-0.4-0.60.2-0.6
Bone: elastic work0.91.23.2-0.8-0.3-0.50.4-1.0-1.0-1.1-1.0-1.0-1.0-1.5-1.0-1.0-1.4-1.8-1.3-1.3-1.3
Bone: endosteal estimation1.12.511.00.80.60.5-0.31.11.11.21.01.31.31.31.31.12.22.03.2-0.33.3
Bone: endosteal perimeter1.53.213.10.90.60.5-0.31.41.41.51.21.41.51.81.41.42.42.43.5-0.13.6
Epididymis fat weight3.210.814.93.33.02.9-2.83.63.63.53.43.33.33.93.43.53.13.33.32.13.5
Delta time in closed arm before/after self-admin0.20.21.1-0.20.30.1-0.1-0.4-0.3-0.3-0.3-0.3-0.3-0.9-0.4-0.3-0.5-1.0-0.4-0.70.0
Delta time in open arm before/after self-admin0.30.30.8-0.6-0.9-0.70.8-0.5-0.5-0.5-0.5-0.4-0.4-0.0-0.4-0.6-0.40.1-0.20.50.0
Diff in mean of infusions in LGA sessions0.50.60.9-0.8-0.7-0.70.7-0.9-0.9-0.9-0.7-0.8-0.8-0.9-0.8-0.9-0.9-0.9-0.9-0.70.0
Delay discount exponential model param0.00.00.20.00.20.1-0.2-0.1-0.1-0.2-0.10.00.10.30.00.1-0.4-0.30.1-0.10.0
Extinction: sum of active levers before priming2.32.64.5-1.9-2.1-2.02.1-1.8-1.8-1.8-1.8-1.6-1.6-1.6-1.6-1.8-0.8-0.7-0.3-1.30.0
Active lever presses in extinction session 63.33.24.8-2.1-2.1-2.22.2-1.8-1.8-1.9-1.9-2.0-2.0-1.7-1.9-2.0-1.6-1.3-0.0-1.80.0
Bone: final force2.53.95.3-2.3-2.1-2.32.3-2.2-2.2-2.2-2.2-2.1-2.1-2.0-2.1-2.1-1.4-1.4-0.2-2.20.0
Bone: final moment2.23.64.9-2.2-2.0-2.22.2-2.1-2.1-2.1-2.1-2.1-2.0-1.9-2.0-2.0-1.4-1.4-0.1-2.10.0
Food consumed during 24 hour testing period0.10.10.5-0.1-0.1-0.10.0-0.1-0.1-0.2-0.2-0.2-0.30.0-0.3-0.2-0.7-0.4-0.7-0.0-0.6
Glucose2.64.17.51.81.61.6-1.42.12.12.22.02.02.02.02.02.22.72.32.51.02.4
Heart weight1.32.05.51.01.00.9-0.71.51.41.61.21.21.20.81.21.22.21.52.30.22.3
Delay discount hyperbolic model param0.00.00.30.00.20.1-0.2-0.2-0.2-0.3-0.10.00.00.20.00.2-0.5-0.4-0.1-0.10.0
Intermittent access intake day 1-15 change0.71.52.91.31.11.2-1.21.31.31.21.31.41.31.71.41.30.81.20.91.30.2
Intermittent access intake escalation0.61.22.51.21.01.1-1.01.21.21.01.11.31.21.61.21.10.61.00.81.20.1
Intermittent access intake escalation 20.91.02.21.10.91.0-1.01.11.11.01.01.21.11.51.11.10.61.00.71.20.1
Intermitt. access day 1 inactive lever presses0.10.31.90.40.30.4-0.40.30.40.40.50.30.40.50.40.40.20.4-0.31.3-1.4
Intermitt. access day 15 inactive lever presses1.22.55.01.51.11.2-1.11.51.51.61.61.61.72.01.61.61.62.01.82.20.7
Intermitt. access escalation Index2.83.94.92.11.92.0-1.92.22.22.22.02.02.11.92.02.02.01.91.11.62.1
Intermittent access day 1 total infusions2.94.613.41.61.11.1-0.92.12.12.11.71.91.92.21.81.92.92.93.71.83.0
Intermittent access day 15 total infusions5.07.511.42.62.22.2-2.12.92.92.82.72.92.83.32.82.82.83.13.42.62.2
Intermittent access terminal intake (last 3 days)5.06.614.22.21.81.8-1.62.62.62.62.42.62.53.02.52.52.83.13.82.22.8
Intermittent access total infusions4.55.413.71.91.51.5-1.32.32.32.32.02.32.22.62.22.22.82.93.71.92.7
Intermittent access day 1 locomotion2.53.27.51.41.11.1-0.91.91.81.81.51.61.61.91.61.72.32.42.71.71.8
Intermittent access day 15 total locomotion3.36.09.82.21.61.8-1.62.52.42.42.42.62.53.12.52.42.63.13.12.72.0
Intermittent access total locomotion7.69.118.32.61.82.0-1.73.02.93.02.82.92.93.62.92.93.64.04.33.03.3
Intermittent access standard deviation0.91.93.11.51.41.4-1.41.61.61.51.41.41.41.71.41.40.91.11.01.8-0.3
Left kidney weight0.73.15.71.51.11.2-1.12.02.02.01.61.71.61.61.81.42.12.12.11.82.4
Right kidney weight0.31.31.91.11.11.0-1.01.41.41.31.11.21.11.21.21.11.01.01.21.01.3
Cocaine induced anxiety0.00.10.2-0.3-0.4-0.40.4-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.2-0.10.10.00.5-0.5
Post-drug Anxiety0.80.92.0-1.0-1.0-1.01.0-1.2-1.2-1.1-1.0-0.9-0.9-0.8-0.9-0.7-0.7-0.6-0.3-1.4-0.4
Baseline Anxiety0.60.62.9-0.5-0.2-0.30.3-0.8-0.8-0.8-0.8-0.7-0.7-0.9-0.7-0.6-0.8-1.1-0.9-1.7-0.6
Tail length0.62.25.6-1.1-0.7-0.80.6-1.1-1.0-1.2-1.3-1.4-1.4-1.7-1.4-1.4-2.0-2.2-2.3-0.4-2.4
Length with tail1.98.511.8-2.9-2.3-2.62.4-2.9-2.9-3.0-3.1-3.1-3.0-3.3-3.1-3.0-3.2-3.4-2.5-2.9-2.4
Length without tail2.16.912.3-2.5-1.8-2.12.0-2.7-2.7-2.7-2.7-2.6-2.7-3.0-2.8-2.6-2.9-3.3-2.1-3.5-1.6
Times rat made contact with spout0.50.51.2-0.7-0.7-0.60.6-0.6-0.6-0.6-0.6-0.7-0.7-1.0-0.8-0.8-0.6-0.7-1.10.0-0.9
Lifetime Intake3.34.010.71.61.41.3-1.12.02.02.01.71.91.82.21.81.92.42.43.31.52.4
Liver weight, left0.81.32.51.31.61.4-1.41.31.31.31.21.21.21.01.21.20.90.50.9-0.11.1
Liver weight, right2.13.66.52.22.52.3-2.32.12.12.12.12.12.11.62.02.01.51.01.40.60.8
Locomotor activity2.03.17.02.22.62.5-2.51.81.81.82.01.91.91.51.82.00.70.30.10.9-0.0
Locomotor testing distance2.24.09.42.53.12.8-2.92.12.12.12.22.02.11.62.12.30.80.20.00.90.0
Locomotor testing rearing1.83.67.22.32.72.6-2.62.12.12.12.21.92.01.51.91.90.90.50.11.3-0.1
Locomotion in novel chamber4.96.39.02.62.52.5-2.42.82.82.72.62.72.73.02.62.82.32.42.31.80.0
Locomotion in novel chamber post-restriction2.64.36.62.21.82.0-1.92.32.32.22.22.22.22.42.12.01.92.21.62.60.0
Fecal boli incidents, locomotor time 10.10.10.4-0.2-0.6-0.50.5-0.1-0.1-0.1-0.1-0.1-0.10.3-0.0-0.30.00.70.5-0.30.0
Change in fecal boli incidents, locomotor task0.10.10.20.10.50.3-0.3-0.1-0.1-0.00.10.00.1-0.20.00.40.3-0.40.5-0.50.0
Time >=10cm from walls, locomotor time 11.21.27.40.4-0.1-0.00.20.70.70.80.60.80.71.20.80.71.82.12.70.80.0
Bouts of movement, locomotor time 11.82.15.9-1.3-1.6-1.31.2-1.5-1.4-1.5-1.4-1.6-1.4-1.2-1.8-1.2-1.7-1.3-2.4-0.20.0
Total resting periods, locomotor time 11.21.33.5-1.1-1.4-1.11.1-1.2-1.2-1.2-1.1-1.3-1.1-0.9-1.4-1.0-1.2-0.8-1.90.10.0
Rest time, locomotor task time 11.21.52.31.41.41.3-1.31.41.41.41.31.21.31.51.11.50.91.00.90.90.0
Distance moved, locomotor task time 10.10.20.4-0.5-0.6-0.60.6-0.3-0.3-0.2-0.4-0.3-0.3-0.3-0.1-0.50.40.30.5-0.40.0
Vertical activity count, locomotor time 10.41.01.41.21.11.1-1.11.01.01.11.11.21.11.11.21.01.00.80.60.40.0
Time >=10cm from walls, locomotor time 20.10.10.5-0.4-0.7-0.60.6-0.1-0.1-0.2-0.3-0.3-0.40.2-0.3-0.2-0.00.40.00.40.0
Bouts of movement, locomotor time 20.40.61.4-0.8-1.0-0.80.8-0.8-0.8-0.9-0.7-0.7-0.7-0.7-0.9-0.7-0.7-0.4-1.20.00.0
Total resting periods, locomotor time 20.10.20.6-0.5-0.8-0.50.6-0.5-0.5-0.6-0.4-0.4-0.4-0.3-0.6-0.4-0.3-0.0-0.70.40.0
Rest time, locomotor task time 22.32.94.51.71.61.6-1.51.91.91.91.81.61.71.81.52.11.61.61.52.10.0
Distance moved, locomotor task time 21.21.52.1-1.2-1.1-1.11.0-1.2-1.2-1.2-1.3-1.2-1.3-1.3-1.2-1.3-1.3-1.3-1.4-1.30.0
Vertical activity count, locomotor time 20.30.31.50.30.70.6-0.7-0.00.0-0.10.10.10.1-0.20.1-0.1-0.8-1.1-1.2-1.10.0
Light reinforcement 10.10.21.00.40.40.5-0.50.30.30.30.30.40.30.10.40.2-0.1-0.0-0.51.0-0.5
Light reinforcement 20.61.01.80.90.60.7-0.61.11.11.01.01.01.01.31.00.90.81.21.10.81.2
Bone: marrow area1.22.711.40.90.70.6-0.41.21.21.31.11.31.31.41.41.22.32.13.3-0.33.4
Bone: maximum diameter0.30.62.2-0.7-0.8-0.90.9-0.5-0.5-0.6-0.6-0.5-0.5-0.2-0.5-0.6-0.3-0.01.0-1.51.2
Bone: maximum force3.25.69.7-2.8-2.9-3.03.1-2.6-2.6-2.5-2.6-2.5-2.5-2.1-2.5-2.4-1.1-1.00.6-2.60.8
Bone: maximum moment2.95.18.8-2.7-2.8-2.93.0-2.5-2.5-2.4-2.5-2.4-2.4-2.1-2.3-2.3-1.0-1.00.6-2.40.8
Mean time between licks in bursts0.20.51.7-0.40.1-0.10.0-0.6-0.6-0.6-0.5-0.5-0.5-1.1-0.6-0.5-0.8-1.3-0.9-1.3-1.0
Mean num. licks in bursts0.20.30.70.60.60.6-0.70.50.50.60.60.50.50.30.50.50.30.1-0.30.8-0.4
Cd content in liver1.21.43.11.10.70.9-0.81.11.11.11.21.21.21.51.20.91.11.50.91.81.0
Co content in liver1.61.84.11.61.81.9-2.01.41.41.31.41.21.20.81.21.0-0.0-0.2-1.41.6-1.2
Cu content in liver0.10.10.70.1-0.3-0.00.10.10.10.20.20.20.20.10.20.10.50.6-0.10.8-0.1
Fe content in liver0.20.32.0-0.3-0.0-0.30.2-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.5-0.5-0.80.1-1.4-0.1
K content in liver0.50.51.9-0.7-0.7-0.80.8-0.7-0.7-0.6-0.7-0.6-0.6-0.8-0.6-0.7-0.0-0.30.3-1.40.7
Mg content in liver0.40.40.90.60.60.6-0.60.60.60.70.60.70.70.40.60.60.80.60.5-0.01.0
Mn content in liver3.43.74.8-2.1-2.1-2.22.1-2.1-2.1-2.2-2.1-2.1-2.1-1.8-2.1-2.0-1.6-1.4-0.6-2.2-0.4
Na content in liver0.40.51.1-0.6-0.4-0.50.4-0.6-0.6-0.7-0.7-0.7-0.7-0.8-0.6-0.8-1.1-1.0-0.5-0.7-0.5
Rb content in liver2.02.33.21.71.71.7-1.71.61.61.71.71.61.61.51.61.81.51.10.61.00.9
Se content in liver0.20.20.70.30.10.2-0.10.40.40.40.40.40.40.70.50.20.50.70.60.20.9
Sr content in liver2.92.53.6-1.6-1.5-1.51.4-1.6-1.6-1.7-1.7-1.7-1.7-1.6-1.7-1.7-1.9-1.6-1.5-0.8-1.3
Zn content in liver0.30.30.6-0.6-0.7-0.60.6-0.5-0.5-0.5-0.5-0.5-0.5-0.8-0.5-0.8-0.3-0.3-0.70.1-0.6
Bone: minimum diameter1.22.18.80.70.30.3-0.11.11.11.21.01.21.21.21.21.12.32.22.60.43.0
Time in familiar zone, hab. session 10.40.30.80.50.30.4-0.30.50.50.60.40.60.50.60.60.60.90.80.80.20.9
Time in novel zone, hab. session 10.30.30.80.60.90.8-0.90.40.40.30.50.30.40.10.30.4-0.4-0.6-0.6-0.1-0.5
Total zone transitions, hab. session 10.60.81.4-1.0-1.2-1.11.1-1.0-1.0-0.9-1.0-1.0-1.0-0.9-0.9-0.9-0.5-0.4-0.6-0.1-0.6
Total locomotion distance, hab. session 10.30.51.20.40.30.3-0.20.60.60.70.50.60.50.70.60.71.11.01.10.21.0
Locomotion velocity, hab. session 10.10.10.4-0.1-0.2-0.20.20.10.10.20.10.10.10.20.10.20.60.60.60.10.5
Time in familiar zone, hab. session 20.20.20.90.30.70.5-0.6-0.0-0.0-0.00.10.20.3-0.40.2-0.1-0.4-0.8-0.3-1.0-0.4
Time in novel zone, hab. session 20.10.20.6-0.4-0.7-0.50.6-0.2-0.2-0.1-0.2-0.4-0.40.0-0.3-0.10.20.40.00.80.1
Total zone transitions, hab. session 21.31.63.3-1.6-1.8-1.71.8-1.3-1.3-1.1-1.4-1.4-1.4-1.4-1.3-1.2-0.0-0.20.2-1.00.4
Total locomotion distance, hab. session 20.20.31.5-0.2-0.3-0.40.50.10.10.2-0.0-0.0-0.0-0.10.00.11.00.71.2-0.31.2
Locomotion velocity, hab. session 20.40.52.4-0.1-0.2-0.30.40.30.30.40.20.20.20.20.20.31.31.01.6-0.11.6
Novel to familiar place preference ratio1.11.22.9-1.3-1.7-1.51.6-1.1-1.1-1.2-1.2-1.2-1.2-0.6-1.2-1.2-0.6-0.1-0.10.0-0.3
Novelty place preference0.50.61.7-0.9-1.3-1.11.2-0.7-0.7-0.8-0.8-0.8-0.8-0.2-0.7-0.8-0.30.20.00.5-0.2
Time in novel zone, NPP test0.40.41.2-0.8-1.1-0.91.0-0.6-0.6-0.6-0.6-0.7-0.7-0.2-0.6-0.7-0.20.10.00.4-0.1
Total zone transitions, NPP test2.13.14.8-2.1-2.2-2.22.2-1.9-1.9-1.8-2.0-2.0-2.0-1.9-1.9-1.9-1.0-1.0-0.5-1.1-0.3
Total locomotion distance, NPP test0.10.10.4-0.4-0.5-0.50.5-0.2-0.2-0.1-0.3-0.3-0.3-0.2-0.2-0.10.50.30.5-0.20.6
Locomotion velocity, NPP test0.10.20.4-0.5-0.6-0.60.6-0.3-0.3-0.2-0.4-0.4-0.4-0.2-0.3-0.20.40.30.40.10.4
Intraocular pressure0.81.22.71.21.01.2-1.21.21.21.11.21.11.11.61.31.10.30.90.31.5-0.3
Delta distance traveled before/after self-admin0.30.31.10.60.90.8-0.90.20.30.20.50.40.40.10.40.5-0.3-0.5-1.10.40.0
Delta ambulatory time before/after self-admin0.20.21.20.40.70.6-0.70.10.1-0.00.30.20.2-0.10.20.3-0.5-0.7-1.10.10.0
Parametrial fat weight3.58.311.22.72.22.3-2.13.03.03.02.83.03.03.23.02.83.33.33.22.43.0
Pavlov. Cond. lever latency0.30.30.70.70.80.8-0.80.60.60.50.70.50.60.60.60.60.00.1-0.30.4-0.3
Pavlov. Cond. magazine entry latency0.40.51.5-0.8-1.2-1.11.1-0.5-0.5-0.4-0.6-0.5-0.6-0.5-0.6-0.70.30.40.50.40.5
Pavlov. Cond. change in total contacts0.30.31.1-0.5-1.1-0.80.9-0.3-0.3-0.3-0.3-0.2-0.3-0.0-0.4-0.40.30.80.41.00.4
Pavlov. Cond. index score0.20.30.8-0.7-0.9-0.80.8-0.5-0.5-0.5-0.6-0.5-0.5-0.5-0.6-0.6-0.20.0-0.00.30.1
Pavlov. Cond. latency score0.20.20.6-0.6-0.7-0.70.7-0.3-0.3-0.4-0.5-0.4-0.4-0.4-0.5-0.50.10.10.20.20.3
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.5-0.50.6-0.3-0.3-0.2-0.4-0.2-0.3-0.4-0.3-0.30.20.10.5-0.20.6
Pavlov. Cond. magazine entry number0.40.41.10.71.00.9-0.90.70.60.70.70.60.60.50.70.80.50.10.4-0.70.4
Pavlov. Cond. intertrial magazine entries0.60.71.41.00.80.9-0.90.80.80.70.80.91.01.10.90.80.40.7-0.01.20.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.4-0.9-1.2-1.11.1-0.7-0.7-0.7-0.8-0.7-0.7-0.7-0.8-0.8-0.20.00.00.30.1
Pavlov. Cond. response bias0.20.30.7-0.6-0.9-0.70.7-0.5-0.5-0.6-0.6-0.5-0.5-0.4-0.6-0.6-0.3-0.0-0.20.5-0.2
Pavlov. Cond. lever latency0.60.81.31.01.11.1-1.10.90.91.01.01.01.00.61.00.90.70.4-0.21.0-0.3
Pavlov. Cond. magazine entry latency4.25.18.1-2.6-2.9-2.72.8-2.4-2.4-2.4-2.5-2.4-2.4-2.4-2.4-2.6-1.6-1.3-1.0-1.2-0.9
Pavlov. Cond. change in total contacts1.52.35.5-1.8-2.3-2.12.2-1.6-1.6-1.7-1.7-1.6-1.6-1.0-1.6-1.6-0.8-0.1-0.1-0.5-0.1
Pavlov. Cond. index score2.43.25.9-2.2-2.4-2.32.4-1.9-1.9-1.9-2.1-2.0-2.0-1.5-2.0-2.0-1.1-0.7-0.3-1.2-0.2
Pavlov. Cond. latency score2.02.75.0-2.0-2.2-2.22.2-1.7-1.7-1.8-1.9-1.8-1.8-1.4-1.8-1.8-0.9-0.6-0.1-1.20.1
Pavlov. Cond. lever contacts0.60.81.3-1.1-1.1-1.11.2-0.9-0.9-1.0-1.0-1.0-1.0-0.6-1.0-0.9-0.7-0.40.1-0.90.2
Pavlov. Cond. magazine entry number7.08.613.33.43.63.5-3.53.23.23.23.33.23.22.83.23.22.21.81.51.61.4
Pavlov. Cond. intertrial magazine entries0.91.41.81.31.31.3-1.21.21.21.21.31.31.31.31.41.31.00.90.80.70.9
Pavlov. Cond. lever-magazine prob. diff.2.93.97.0-2.4-2.6-2.52.6-2.1-2.1-2.1-2.3-2.2-2.2-1.7-2.1-2.2-1.3-0.9-0.5-1.3-0.4
Pavlov. Cond. response bias2.02.84.7-2.0-2.2-2.12.1-1.7-1.7-1.8-1.9-1.9-1.9-1.5-1.9-1.9-1.2-0.8-0.4-1.2-0.2
Time in closed arm before self-admin0.30.31.20.40.10.2-0.10.50.50.50.40.50.50.90.60.60.91.10.90.30.0
Time in closed arm after self-admin0.30.30.60.70.80.7-0.70.40.40.40.60.60.60.50.70.70.70.50.50.10.0
Time in open arm before self-admin0.40.41.30.71.11.0-1.10.60.60.60.50.40.4-0.30.30.4-0.0-0.6-1.0-0.10.0
Time in open arm after self-admin0.10.21.0-0.2-0.1-0.10.0-0.1-0.1-0.1-0.3-0.3-0.3-0.5-0.4-0.4-0.6-0.7-1.00.30.0
Bone: periosteal estimation0.30.75.2-0.3-0.4-0.60.7-0.1-0.1-0.0-0.10.00.10.20.1-0.00.80.82.1-1.12.3
Bone: periosteal perimeter0.30.62.6-0.7-0.7-0.90.9-0.4-0.4-0.4-0.5-0.4-0.4-0.1-0.4-0.40.30.41.4-1.31.6
Bone: post-yield work2.02.911.0-1.5-2.3-2.22.5-0.9-0.9-0.7-1.0-0.8-0.8-0.1-0.8-0.61.82.03.0-0.73.3
Progressive ratio test 1 active lever presses0.40.51.30.50.40.4-0.30.80.80.70.50.60.60.80.60.60.70.81.10.90.7
Progressive ratio test 1 breakpoint0.30.41.20.40.30.3-0.20.70.70.60.50.50.50.80.50.50.60.71.10.80.7
Progressive ratio test 1 inactive lever presses0.10.21.40.30.10.2-0.20.30.40.30.30.30.30.50.30.20.20.40.01.2-0.8
Progressive ratio test 2 active lever presses2.73.15.11.61.31.3-1.21.91.91.81.61.91.82.21.81.81.72.12.31.91.4
Progressive ratio test 2 breakpoint2.73.04.91.61.31.4-1.21.91.91.81.61.81.72.21.81.81.72.02.21.81.3
Progressive ratio test 2 inactive lever presses6.310.214.83.22.62.8-2.73.33.33.33.23.43.33.83.33.33.13.63.03.52.0
Incentive Sensitization - Responses0.20.21.7-0.1-0.3-0.30.40.10.10.1-0.10.20.10.40.10.10.60.81.3-0.01.0
Incentive Sensitization - Breakpoint0.30.32.00.2-0.0-0.00.10.40.30.30.10.50.30.60.40.40.80.91.40.21.0
Sum of active levers in priming session hrs 5-61.21.13.1-1.0-1.0-1.01.0-1.2-1.2-1.4-1.0-1.0-1.0-0.5-0.9-1.0-1.8-1.1-0.7-1.10.0
Progressive ratio1.01.64.2-1.6-1.9-1.92.0-1.1-1.1-0.9-1.3-1.2-1.2-1.1-1.4-1.30.40.31.1-0.80.0
Food seeking constrained by brief footshock0.10.10.3-0.10.0-0.00.0-0.4-0.4-0.4-0.1-0.2-0.2-0.4-0.2-0.2-0.2-0.4-0.3-0.50.0
Seeking ratio, punishment vs. effort1.42.05.31.92.22.2-2.31.31.31.21.61.41.41.11.61.50.1-0.2-0.80.70.0
Retroperitoneal fat weight9.339.747.36.86.66.5-6.36.96.96.96.86.76.76.76.76.85.95.44.74.94.4
Reaction time number correct0.20.41.3-0.5-0.2-0.40.3-0.4-0.4-0.5-0.6-0.8-0.8-0.5-0.6-0.5-1.0-1.2-0.6-0.9-0.7
Reaction time mean minus median1.94.78.0-2.6-2.8-2.72.7-2.4-2.4-2.3-2.3-2.3-2.2-1.8-2.5-2.3-1.6-1.1-0.7-1.7-1.1
Reaction time mean minus median AUC1.02.43.4-1.8-1.8-1.81.8-1.7-1.7-1.7-1.6-1.7-1.6-1.3-1.8-1.6-1.4-1.1-0.7-1.3-1.3
Reaction time num false alarms0.40.61.81.01.31.2-1.30.60.60.60.60.80.80.30.80.90.3-0.3-0.4-0.1-0.3
Reaction time num false alarms AUC0.10.20.60.30.70.5-0.6-0.0-0.0-0.0-0.00.10.1-0.30.10.2-0.2-0.7-0.8-0.5-0.8
Reaction time trials correct on left0.20.41.3-0.5-0.2-0.40.3-0.4-0.4-0.5-0.6-0.8-0.8-0.5-0.6-0.5-1.0-1.2-0.6-0.9-0.7
Reaction time trials on left0.30.61.6-0.6-0.2-0.40.3-0.5-0.5-0.6-0.7-0.9-0.9-0.6-0.7-0.5-1.1-1.3-0.7-1.0-0.8
Reaction time mean0.10.20.6-0.4-0.8-0.50.6-0.3-0.3-0.4-0.4-0.4-0.20.2-0.4-0.1-0.10.3-0.30.3-0.4
Reaction time mean AUC0.10.10.6-0.3-0.8-0.50.6-0.3-0.3-0.3-0.3-0.3-0.10.3-0.3-0.00.10.5-0.20.4-0.4
Median of all reaction times0.10.20.70.2-0.20.1-0.00.30.30.30.20.20.40.70.30.50.50.8-0.10.8-0.0
Reaction time omissions1.72.53.4-1.8-1.8-1.81.8-1.8-1.8-1.7-1.6-1.8-1.7-1.3-1.8-1.4-1.3-1.1-1.1-1.3-1.5
Reaction time false alarm rate0.30.41.00.81.00.9-1.00.50.50.50.60.80.80.20.70.70.50.1-0.1-0.0-0.0
Reaction time premature initiation rate2.73.76.5-1.8-1.2-1.41.3-2.0-1.9-1.9-2.0-1.9-1.9-2.4-2.1-1.9-2.1-2.6-1.9-2.4-1.4
Reaction time premature initiations3.46.011.0-2.2-1.6-1.81.6-2.4-2.4-2.4-2.5-2.5-2.6-2.8-2.6-2.3-2.9-3.3-2.6-2.7-2.3
Std. dev. reaction times0.81.52.8-1.4-1.7-1.51.6-1.4-1.4-1.3-1.3-1.3-1.3-0.8-1.4-1.1-0.9-0.5-0.6-0.8-1.0
Reaction time trials completed0.30.61.6-0.6-0.2-0.40.3-0.5-0.5-0.6-0.7-0.9-0.9-0.6-0.7-0.5-1.1-1.3-0.7-1.0-0.8
Reaction time trials AUC0.20.31.2-0.4-0.0-0.20.2-0.4-0.4-0.5-0.5-0.7-0.7-0.5-0.5-0.4-0.9-1.1-0.5-0.9-0.6
Run reversals in cocaine runway, females0.30.30.9-0.5-0.5-0.60.6-0.5-0.5-0.3-0.6-0.6-0.6-0.9-0.4-0.60.4-0.00.7-0.70.0
Run reversals in cocaine runway, males0.40.41.30.81.21.0-1.10.50.60.50.70.60.60.60.60.4-0.4-0.4-0.30.40.0
Latency to leave start box in cocaine runway0.20.31.40.1-0.2-0.10.20.20.20.30.30.40.40.30.40.21.11.11.20.40.0
Latency to leave start box in cocaine runway, F0.10.11.00.0-0.3-0.10.20.20.20.30.20.10.10.00.2-0.00.70.80.41.00.0
Latency to leave start box in cocaine runway, M0.20.21.3-0.1-0.0-0.20.3-0.2-0.2-0.2-0.00.10.10.10.10.10.40.31.2-1.10.0
Std. dev. time between licks in bursts0.20.20.80.40.90.6-0.70.20.20.10.20.20.2-0.30.10.2-0.4-0.9-0.5-0.9-0.3
Total sessions with >9 infusions0.30.32.3-0.1-0.2-0.30.40.20.20.2-0.10.10.00.20.00.20.80.71.5-0.21.5
Short access day 1 total inactive lever presses2.22.93.81.91.81.8-1.71.61.61.71.71.71.82.01.81.91.81.71.71.40.5
Short access day 10 total inactive lever presses0.30.81.91.01.01.1-1.10.70.80.80.90.80.90.70.90.80.60.5-0.01.1-1.4
Short access day 1 total infusions1.82.45.81.31.11.1-0.91.51.51.61.31.41.51.51.41.52.01.92.41.21.8
Short access day 10 total infusions1.31.68.70.40.00.00.20.90.90.90.60.70.71.00.70.82.12.03.00.92.2
Short access total infusions0.91.26.60.60.50.3-0.20.90.90.90.60.80.70.90.70.91.71.52.60.31.8
Short access day 1 locomotion1.82.23.41.41.21.2-1.11.51.51.51.41.61.51.61.51.51.81.81.81.41.4
Short access day 10 total locomotion0.91.74.40.90.50.6-0.51.31.31.31.11.01.11.41.21.11.71.92.11.41.3
Short access total locomotion1.82.24.81.20.90.9-0.81.51.51.51.21.31.41.61.41.41.92.02.21.41.7
One hour access (0.3 mA shock)7.08.110.43.02.72.7-2.63.13.13.02.93.03.03.23.02.92.62.72.72.71.8
Compulsive drug intake2.42.88.2-1.2-0.6-0.70.5-1.5-1.5-1.5-1.4-1.6-1.5-2.1-1.5-1.6-2.1-2.5-2.9-1.9-1.6
One hour access (shock baseline)6.49.814.13.02.52.6-2.43.33.33.33.13.33.23.83.23.23.13.53.53.32.2
Social response proportion0.70.81.3-1.0-1.1-1.01.0-1.1-1.1-1.1-1.0-0.8-0.9-0.8-0.9-0.9-0.8-0.5-0.4-0.9-0.5
Social responses0.30.40.9-0.5-0.3-0.40.3-0.6-0.6-0.6-0.5-0.5-0.5-0.6-0.6-0.6-0.8-0.8-0.8-0.7-0.9
Social time0.40.61.5-0.6-0.3-0.40.4-0.6-0.6-0.6-0.5-0.9-0.9-0.7-0.8-0.6-1.1-1.2-0.9-0.6-1.2
Soleus weight4.112.014.73.83.73.7-3.63.83.83.83.83.73.73.63.83.83.02.82.12.72.4
Bone: stiffness2.44.07.5-2.4-2.7-2.72.7-2.2-2.2-2.1-2.2-2.1-2.1-1.7-2.1-2.0-0.9-0.60.3-1.80.6
Tibialis anterior weight10.134.341.5-6.3-5.6-6.05.8-6.3-6.3-6.3-6.3-6.4-6.4-6.1-6.4-6.3-5.7-5.5-3.3-5.5-3.6
Time to tail flick, vehicle, before self-admin0.20.30.7-0.6-0.7-0.70.8-0.3-0.3-0.3-0.5-0.5-0.5-0.4-0.5-0.40.10.10.6-0.80.0
Time to tail flick, vehicle, after self-admin0.50.71.6-1.0-1.1-1.21.3-0.6-0.6-0.4-0.8-0.8-0.8-1.1-0.8-1.00.4-0.01.0-0.80.0
Time to tail flick, test, before self-admin2.12.24.51.41.31.3-1.21.61.51.61.41.51.51.41.51.52.11.82.00.90.0
Time to tail flick, test, after self-admin0.10.10.1-0.3-0.3-0.40.4-0.2-0.2-0.3-0.2-0.3-0.3-0.0-0.2-0.3-0.3-0.10.2-0.30.0
Delta time to tail flick, vehicle, before/after SA0.30.30.6-0.7-0.6-0.70.7-0.6-0.6-0.5-0.5-0.6-0.6-0.8-0.6-0.7-0.0-0.30.2-0.40.0
Delta time to tail flick, test, before/after SA2.22.26.3-1.3-1.1-1.11.0-1.4-1.4-1.6-1.3-1.5-1.5-1.2-1.5-1.5-2.5-2.0-2.3-0.80.0
Tibia length1.02.74.2-1.9-2.0-2.12.0-1.8-1.8-1.9-1.8-1.7-1.8-1.1-1.6-1.8-1.6-0.8-0.2-1.30.2
Ambulatory time before self-admin0.40.61.8-0.9-1.4-1.21.3-0.7-0.8-0.7-0.8-0.7-0.7-0.3-0.7-0.9-0.00.40.5-0.30.0
Ambulatory time after self-admin0.20.31.20.3-0.10.1-0.10.30.30.30.40.40.40.70.40.40.71.00.31.10.0
Bone: tissue strength0.00.00.1-0.1-0.2-0.10.2-0.2-0.2-0.1-0.1-0.0-0.00.2-0.00.10.20.20.20.10.1
Total heroin consumption5.36.27.8-2.8-2.8-2.72.7-2.7-2.7-2.7-2.7-2.7-2.7-2.7-2.7-2.8-2.2-2.0-1.7-2.20.0
Bone: trabecular number0.81.33.0-1.4-1.7-1.61.7-1.2-1.2-1.1-1.2-1.0-1.1-0.8-1.0-1.10.00.20.8-0.91.1
Bone: trabecular spacing0.50.71.30.91.11.1-1.10.91.00.90.80.70.70.50.70.90.3-0.0-0.51.0-0.8
Bone: trabecular thickness0.40.61.30.50.30.4-0.30.50.50.60.60.70.60.80.70.71.11.11.10.61.1
Bone: trabecular tissue density3.85.67.22.72.52.6-2.62.62.62.62.72.62.72.62.62.41.81.91.12.11.0
Water consumed over 24 hours1.11.53.2-1.1-1.1-1.00.9-1.1-1.1-1.2-1.2-1.3-1.3-1.4-1.3-1.3-1.4-1.3-1.8-0.2-1.5
Number of responses in last shaping day0.10.10.70.20.40.3-0.40.20.20.10.10.10.1-0.10.00.1-0.3-0.4-0.60.4-0.8