Tm7sf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Tm7sf2 0.23 0.11 4.0e-05 0.22 0.2 0.19 0.19 6.9e-06 1.7e-05 3.3e-05 2.7e-05
2 pVTA gene expression Tm7sf2 0.41 0.14 1.0e-14 0.2 0.23 0.21 0.2 4.4e-09 2.5e-10 2.6e-09 3.0e-09
3 BLA gene expression Tm7sf2 0.24 0.1 7.2e-16 0.28 0.27 0.25 0.27 2.2e-15 1.1e-14 1.4e-13 1.2e-14
4 Liver gene expression Tm7sf2 0.19 0.08 0.0e+00 0.12 0.12 0.12 0.12 9.4e-13 4.2e-13 1.1e-12 3.5e-13
5 LHb gene expression Tm7sf2 0.22 0.12 2.6e-04 0.13 0.12 0.12 0.13 5.9e-04 8.0e-04 7.4e-04 6.4e-04
6 Brain gene expression Tm7sf2 0.32 0.16 0.0e+00 0.28 0.28 0.3 0.29 2.9e-26 2.9e-26 6.8e-28 2.8e-27
7 Liver isoform ratio NM_001013071.1 0.03 0.02 3.4e-03 0.01 0.01 0 0.01 8.9e-03 1.7e-02 9.8e-02 2.7e-02
8 Liver isoform ratio XM_039108440.1 0.03 0.02 2.0e-03 0.02 0.01 0.01 0.01 4.8e-03 1.1e-02 4.8e-02 1.6e-02
9 IL gene expression Tm7sf2 0.19 0.11 1.4e-03 0.14 0.12 0.11 0.12 3.4e-04 8.5e-04 1.7e-03 1.0e-03
10 PL gene expression Tm7sf2 0.18 0.1 0.0e+00 0.21 0.18 0.2 0.2 1.0e-22 7.2e-20 2.9e-21 1.9e-21
11 PL mRNA stability Tm7sf2 0.05 0.03 1.1e-05 0.03 0.04 0.05 0.04 2.8e-04 1.1e-05 1.6e-06 1.2e-05
12 Brain mRNA stability Tm7sf2 0.04 0.03 3.1e-04 0.05 0.03 0.03 0.04 3.4e-05 3.9e-04 4.1e-04 1.2e-04
13 NAcc gene expression Tm7sf2 0.1 0.06 3.9e-11 0.1 0.1 0.1 0.1 4.2e-12 2.9e-11 4.1e-11 1.6e-11
14 NAcc mRNA stability Tm7sf2 0.04 0.02 8.2e-05 0.04 0.03 0.03 0.03 5.4e-05 1.3e-04 2.6e-04 1.8e-04
15 Adipose gene expression Tm7sf2 0.18 0.08 2.2e-16 0.08 0.1 0.09 0.1 3.2e-09 1.8e-11 2.7e-10 3.1e-11
16 Adipose mRNA stability Tm7sf2 0.04 0.02 1.5e-03 0.01 0.01 0.01 0.01 2.2e-02 1.0e-02 1.2e-02 1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.30.51.00.7-0.90.7-0.60.60.30.8-0.80.80.70.80.50.50.50.51.0
Area under the delay curve0.10.10.4-0.30.4-0.30.3-0.1-0.0-0.00.0-0.00.1-0.1-0.2-0.20.10.70.5
BMI with tail2.27.09.83.1-3.13.0-2.82.92.22.7-2.72.72.83.02.82.82.60.31.3
BMI without tail1.12.33.91.5-1.51.6-1.41.61.21.5-1.51.51.92.01.71.71.90.00.4
Body weight3.615.218.64.3-4.24.2-4.24.24.04.0-4.04.04.03.94.24.23.9-2.4-1.4
Weight adjusted by age2.32.63.71.6-1.91.7-1.61.71.81.8-1.81.71.61.51.51.51.4-1.5-1.0
Bone surface3.86.712.42.8-3.52.8-2.72.82.62.9-2.92.92.72.22.72.71.9-1.3-0.1
Bone volume1.22.15.21.6-2.31.5-1.51.51.31.6-1.61.71.51.11.41.40.8-0.20.8
Breakpoint value in progressive ratio session3.33.64.72.1-2.22.1-2.11.82.11.9-1.91.92.11.71.91.91.6-1.6-1.0
Number of licking bursts0.30.30.50.7-0.70.7-0.70.50.70.7-0.70.70.50.40.60.60.3-0.4-0.1
Context. condit. distance diff. score1.92.33.1-1.61.8-1.61.6-1.7-1.8-1.61.6-1.6-1.5-1.1-1.4-1.4-1.21.51.1
Locomotion velocity, session 10.10.10.50.00.20.0-0.00.10.20.3-0.30.30.10.30.20.20.6-0.4-0.7
Locomotion distance, session 10.40.61.40.7-0.50.6-0.60.80.70.9-0.90.90.61.20.70.71.00.10.2
Locomotion velocity, session 22.93.44.81.8-1.91.8-1.82.02.02.0-2.02.01.91.82.22.21.9-1.0-0.6
Locomotion distance, session 20.60.91.90.8-0.60.9-0.81.01.01.1-1.11.10.81.41.01.01.3-0.2-0.1
Locomotion velocity, session 30.30.31.2-0.40.4-0.50.5-0.4-0.6-0.50.5-0.5-0.7-0.1-0.5-0.5-0.21.11.1
Locomotion distance, session 30.00.00.1-0.20.3-0.30.2-0.2-0.2-0.10.1-0.1-0.2-0.0-0.1-0.1-0.10.30.2
Stereotopy head waving bouts, day 30.70.91.8-0.80.8-0.80.9-0.8-1.0-1.01.0-1.0-1.1-0.3-0.9-0.9-0.31.31.1
Stereotopy head waving duration, day 30.81.01.3-1.00.8-1.01.0-0.9-1.1-1.11.1-1.1-1.2-0.6-1.0-1.0-0.71.21.0
Locomotion velocity, session 70.80.93.4-0.80.7-0.80.8-0.7-0.9-0.70.7-0.7-0.9-0.1-0.7-0.7-0.61.81.8
Locomotion distance, session 70.10.20.8-0.20.6-0.20.2-0.3-0.4-0.20.2-0.2-0.50.4-0.4-0.40.20.90.6
Stereotopy head waving bouts, day 70.20.31.1-0.4-0.1-0.40.4-0.4-0.5-0.30.3-0.3-0.3-0.5-0.5-0.5-0.80.71.1
Stereotopy head waving duration, day 70.81.02.01.0-1.41.0-1.01.10.91.2-1.21.21.20.81.01.00.6-0.30.3
Locomotion velocity, session 81.11.32.11.1-0.81.1-1.11.11.11.1-1.11.11.10.91.21.21.5-1.3-1.4
Locomotion distance, session 80.20.31.2-0.50.4-0.50.6-0.5-0.6-0.40.4-0.4-0.5-0.1-0.3-0.3-0.31.11.1
Degree of sensitization distance0.10.10.6-0.00.2-0.00.1-0.1-0.3-0.10.1-0.1-0.40.1-0.2-0.20.20.70.7
Degree of sensitization stereotypy0.40.41.30.7-1.10.7-0.70.70.50.8-0.80.80.80.30.60.60.1-0.20.4
Conditioned locomotion1.72.02.41.5-1.41.6-1.51.51.41.3-1.31.21.41.41.41.41.5-1.3-1.1
Cocaine response after cond. corrected1.61.82.7-1.51.7-1.51.5-1.4-1.4-1.41.4-1.4-1.4-1.0-1.4-1.4-0.71.10.5
Cocaine response after cond. not corrected1.21.31.9-1.31.4-1.31.3-1.2-1.2-1.31.3-1.2-1.2-0.9-1.2-1.2-0.61.00.5
Cocaine response before conditioning0.70.91.41.0-1.21.0-1.00.91.10.9-0.91.11.00.61.11.10.5-0.7-0.3
Saline control response4.35.76.92.6-2.22.6-2.62.52.52.3-2.32.32.52.42.42.42.5-2.1-1.8
Bone: connectivity density1.93.04.41.9-2.11.9-1.81.81.61.9-1.92.01.91.81.81.81.6-0.50.1
Bone: cortical apparent density0.30.40.60.6-0.20.7-0.70.60.80.5-0.50.50.50.80.70.70.6-0.7-0.8
Bone: cortical area0.60.92.01.0-1.41.0-1.01.00.91.0-1.01.01.10.71.01.00.6-0.8-0.3
Bone: cortical porosity0.10.10.20.3-0.30.3-0.30.30.00.2-0.20.40.20.40.40.40.30.20.3
Bone: cortical porosity0.60.60.90.9-0.80.9-0.80.80.60.8-0.80.90.80.91.01.00.9-0.4-0.2
Bone: cortical thickness2.94.76.02.2-1.72.1-2.22.22.32.0-2.02.12.22.12.22.22.3-2.4-2.4
Bone: cortical thickness0.70.92.80.8-0.20.7-0.80.80.90.8-0.80.90.80.90.70.71.2-1.3-1.7
Bone: cortical tissue density0.40.50.90.7-0.20.8-0.80.70.90.6-0.60.60.60.90.80.80.8-0.9-0.9
Condit. Reinf. active minus inactive responses0.10.20.40.4-0.20.5-0.40.40.30.5-0.50.50.30.60.40.40.5-0.1-0.0
Condit. Reinf. active-inactive response ratio0.00.00.10.20.10.1-0.20.10.10.1-0.10.10.10.40.10.10.2-0.2-0.2
Condit. Reinf. active responses0.00.10.30.2-0.20.3-0.20.10.00.2-0.20.2-0.00.30.10.10.00.40.6
Condit. Reinf. inactive responses0.20.21.4-0.2-0.1-0.10.2-0.3-0.3-0.10.1-0.1-0.4-0.3-0.3-0.3-0.50.91.2
Incentive salience index mean0.30.30.60.6-0.50.6-0.60.50.40.7-0.70.70.50.80.60.60.60.10.3
Condit. Reinf. lever presses0.30.40.90.7-0.90.7-0.60.60.60.7-0.70.70.60.50.70.70.40.00.4
Condit. Reinf. active minus inactive responses0.20.30.8-0.4-0.0-0.40.4-0.3-0.5-0.40.4-0.5-0.4-0.6-0.5-0.5-0.90.60.9
Condit. Reinf. active-inactive response ratio1.11.13.0-0.90.0-0.90.9-0.8-1.0-0.90.9-1.0-0.9-1.3-1.0-1.0-1.51.31.7
Condit. Reinf. active responses0.00.00.20.2-0.30.1-0.20.20.20.1-0.10.10.10.2-0.0-0.0-0.20.20.5
Condit. Reinf. inactive responses0.30.41.10.6-0.10.6-0.60.70.70.6-0.60.80.61.10.60.60.9-0.4-0.5
Condit. Reinf. lever presses2.02.75.11.8-2.31.8-1.81.81.81.6-1.61.71.71.21.81.80.9-1.2-0.4
Condit. Reinf. lever reinforcers received0.20.20.50.6-0.70.5-0.60.60.60.5-0.50.60.50.40.40.40.1-0.20.2
Conditioned reinforcement - actives0.30.30.9-0.6-0.2-0.60.6-0.6-0.0-0.40.4-0.4-0.5-1.0-0.5-0.5-0.80.10.4
Conditioned reinforcement - inactives6.57.310.6-2.62.3-2.72.6-2.9-2.5-2.82.8-2.8-2.6-3.3-2.9-2.9-3.22.11.9
Conditioned locomotion8.510.214.5-3.43.0-3.33.3-3.4-2.8-3.33.3-3.3-3.5-3.8-3.3-3.3-3.52.21.7
Patch foraging indifference point 0 sec0.00.10.10.00.3-0.10.1-0.3-0.2-0.30.3-0.2-0.3-0.2-0.2-0.2-0.10.30.3
Patch foraging indifference point AUC3.94.55.52.2-2.32.2-2.12.32.32.2-2.22.22.31.52.32.31.6-1.9-1.3
Delay disc. indifference point, 0s delay0.40.41.0-1.00.9-0.80.9-0.5-0.4-0.40.4-0.4-0.2-0.4-0.5-0.50.11.00.7
Delay disc. indifference point, 16s delay1.11.11.8-0.91.0-1.00.9-1.0-1.0-1.01.0-1.0-0.9-1.0-1.1-1.1-1.21.41.3
Delay disc. indifference point, 2s delay0.10.10.3-0.40.2-0.30.4-0.3-0.5-0.10.1-0.10.0-0.5-0.3-0.3-0.20.60.6
Delay disc. indifference point, 24s delay0.10.10.4-0.30.7-0.40.3-0.30.0-0.20.2-0.2-0.0-0.1-0.3-0.30.2-0.1-0.5
Delay disc. indifference point, 4s delay0.10.20.6-0.50.8-0.50.5-0.3-0.3-0.20.2-0.20.0-0.1-0.4-0.40.30.60.2
Delay disc. indifference point, 8s delay0.10.10.3-0.30.6-0.20.20.00.2-0.00.0-0.00.10.1-0.1-0.10.40.3-0.0
Indifference point function ln k9.212.817.1-3.74.1-3.83.7-3.8-4.0-3.83.8-3.8-3.8-3.1-3.9-3.9-2.63.01.8
Indifference point function log k9.212.817.1-3.74.1-3.83.7-3.8-4.0-3.83.8-3.8-3.8-3.1-3.9-3.9-2.63.01.8
Patch foraging total patch changes 0 sec0.00.00.10.10.3-0.0-0.0-0.2-0.1-0.20.2-0.1-0.3-0.1-0.1-0.10.1-0.1-0.2
Patch foraging total patch changes 12 sec5.16.68.12.8-2.52.8-2.82.62.82.7-2.72.72.62.32.82.82.2-1.9-1.3
Patch foraging total patch changes 18 sec0.60.81.21.0-1.11.0-0.90.91.00.9-0.90.91.00.51.11.10.5-0.40.0
Patch foraging total patch changes 24 sec3.03.65.01.9-1.92.0-1.91.92.21.9-1.91.91.81.52.12.11.7-2.0-1.6
Patch foraging total patch changes 6 sec0.91.42.21.5-1.01.4-1.41.11.21.0-1.01.11.11.11.31.31.3-0.8-0.6
Patch foraging time to switch 0 sec1.62.54.21.8-2.01.7-1.71.61.51.8-1.81.71.61.51.61.61.1-0.10.7
Patch foraging water rate 0 sec3.86.27.8-2.72.7-2.62.6-2.6-2.6-2.82.8-2.7-2.7-2.5-2.6-2.6-2.41.00.2
Patch foraging water rate 12 sec7.912.118.0-4.04.2-3.93.8-3.7-3.9-3.73.7-3.7-3.6-3.1-3.8-3.8-2.71.60.1
Patch foraging water rate 18 sec3.14.26.4-2.32.5-2.22.2-2.2-2.3-2.32.3-2.2-2.1-1.7-2.2-2.2-1.31.30.4
Patch foraging water rate 24 sec4.05.67.5-2.72.6-2.72.6-2.3-2.5-2.62.6-2.6-2.5-2.2-2.4-2.4-2.11.20.3
Patch foraging water rate 6 sec4.05.88.9-2.63.0-2.62.5-2.5-2.5-2.82.8-2.7-2.6-2.1-2.5-2.5-1.81.0-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.40.10.5-0.0-0.0-0.3-0.3-0.30.3-0.4-0.40.4-0.2-0.2-0.20.60.5
Distance traveled before self-admin0.60.71.50.8-1.20.8-0.81.00.90.9-0.90.90.80.60.90.90.5-0.6-0.1
Distance traveled after self-admin0.20.20.50.6-0.60.6-0.60.70.40.4-0.40.40.40.30.50.50.2-0.4-0.2
Extensor digitorum longus weight7.830.834.85.8-5.85.9-5.85.95.95.8-5.85.85.85.45.85.85.4-4.2-2.9
Bone: elastic displacement1.21.32.7-1.21.7-1.21.1-1.1-1.2-1.31.3-1.3-1.1-1.0-1.3-1.3-0.5-0.0-0.8
Bone: elastic work0.71.02.90.8-0.30.9-0.90.90.90.7-0.70.80.91.00.80.81.4-1.3-1.7
Bone: endosteal estimation1.12.36.6-1.30.5-1.31.5-1.3-1.8-1.21.2-1.2-1.3-1.4-1.4-1.4-1.52.32.6
Bone: endosteal perimeter1.42.98.4-1.50.3-1.51.6-1.5-1.9-1.31.3-1.3-1.5-1.8-1.6-1.6-2.02.42.9
Epididymis fat weight2.96.87.7-2.72.1-2.72.7-2.5-2.7-2.72.7-2.6-2.5-2.8-2.5-2.5-2.72.72.5
Delta time in closed arm before/after self-admin0.10.10.80.10.60.2-0.1-0.10.20.2-0.20.2-0.00.20.00.00.9-0.2-0.8
Delta time in open arm before/after self-admin0.10.10.50.3-0.70.2-0.30.60.30.2-0.20.20.4-0.10.20.2-0.4-0.40.1
Diff in mean of infusions in LGA sessions0.50.61.20.7-0.70.8-0.80.91.10.6-0.60.60.90.50.60.60.5-0.9-0.8
Delay discount exponential model param0.10.10.30.3-0.40.3-0.20.1-0.0-0.00.0-0.0-0.20.00.10.1-0.2-0.5-0.4
Extinction: sum of active levers before priming4.84.86.02.4-2.32.4-2.42.32.22.3-2.32.32.42.42.22.22.1-1.3-0.7
Active lever presses in extinction session 62.92.84.91.5-2.21.6-1.61.72.01.7-1.71.71.81.11.71.71.2-1.9-1.3
Bone: final force3.04.97.02.4-2.62.4-2.42.42.22.3-2.32.42.22.02.42.42.0-1.5-0.8
Bone: final moment2.74.36.22.3-2.52.2-2.22.22.02.2-2.22.32.11.82.22.21.9-1.4-0.8
Food consumed during 24 hour testing period0.10.10.50.2-0.40.2-0.20.20.50.2-0.20.20.2-0.10.30.3-0.2-0.7-0.5
Glucose2.43.75.7-1.81.5-1.81.9-1.7-1.9-2.12.1-2.1-1.9-1.4-1.8-1.8-1.82.42.3
Heart weight3.95.56.6-2.42.6-2.52.4-2.4-2.4-2.52.5-2.5-2.4-2.2-2.3-2.3-1.92.21.6
Delay discount hyperbolic model param0.00.00.20.2-0.30.2-0.20.0-0.0-0.10.1-0.1-0.2-0.00.10.1-0.2-0.4-0.3
Intermittent access intake day 1-15 change0.70.71.7-0.80.4-0.90.7-1.0-0.5-0.90.9-0.9-0.8-1.3-0.8-0.8-1.20.10.2
Intermittent access intake escalation0.70.61.3-0.80.4-0.80.7-1.0-0.6-0.80.8-0.8-0.7-1.2-0.8-0.8-1.10.30.4
Intermittent access intake escalation 20.20.20.6-0.40.0-0.40.3-0.5-0.1-0.40.4-0.4-0.3-0.6-0.4-0.4-0.8-0.3-0.1
Intermitt. access day 1 inactive lever presses2.62.83.9-1.61.6-1.71.6-1.7-1.4-1.71.7-1.7-1.7-2.0-1.8-1.8-1.81.51.3
Intermitt. access day 15 inactive lever presses3.03.35.4-1.71.3-1.81.7-1.8-1.4-1.91.9-1.9-1.9-2.3-1.9-1.9-2.21.51.6
Intermitt. access escalation Index3.73.35.5-1.92.2-1.82.0-1.7-2.3-1.81.8-1.8-1.6-1.4-1.8-1.8-1.32.11.5
Intermittent access day 1 total infusions6.97.912.4-2.82.1-2.72.9-2.7-2.7-2.72.7-2.7-2.8-3.1-2.6-2.6-2.73.53.5
Intermittent access day 15 total infusions9.811.016.5-3.42.5-3.33.4-3.4-3.0-3.33.3-3.3-3.3-4.1-3.3-3.3-3.63.23.1
Intermittent access terminal intake (last 3 days)7.17.712.2-2.81.7-2.72.8-2.8-2.6-2.72.7-2.7-2.7-3.5-2.7-2.7-3.12.93.0
Intermittent access total infusions6.26.89.8-2.61.7-2.52.7-2.5-2.4-2.52.5-2.5-2.6-3.1-2.4-2.4-2.83.03.1
Intermittent access day 1 locomotion4.95.19.3-2.32.0-2.12.3-2.1-2.0-2.22.2-2.2-2.2-2.5-2.1-2.1-1.93.12.8
Intermittent access day 15 total locomotion5.96.39.9-2.51.9-2.52.5-2.6-2.0-2.52.5-2.5-2.5-3.1-2.5-2.5-2.82.52.5
Intermittent access total locomotion7.88.914.0-2.92.1-2.82.9-2.8-2.6-2.92.9-2.9-2.9-3.5-2.8-2.8-3.23.63.7
Intermittent access standard deviation1.31.42.8-1.40.9-1.31.2-1.2-0.7-1.21.2-1.2-1.3-1.7-1.2-1.2-1.40.70.6
Left kidney weight0.71.92.7-1.41.0-1.41.4-1.4-1.5-1.41.4-1.4-1.3-1.4-1.3-1.3-1.61.31.3
Right kidney weight0.10.41.4-0.5-0.1-0.50.5-0.5-0.4-0.60.6-0.6-0.6-1.2-0.3-0.3-1.20.30.6
Cocaine induced anxiety0.00.00.2-0.1-0.50.00.10.0-0.00.1-0.10.10.2-0.20.00.0-0.1-0.10.1
Post-drug Anxiety1.41.63.21.3-1.81.3-1.31.21.61.2-1.21.21.11.11.21.20.9-1.4-0.9
Baseline Anxiety2.72.94.81.9-1.51.8-1.91.62.21.6-1.61.61.51.61.61.61.7-1.7-1.5
Tail length0.92.87.21.2-1.11.4-1.31.51.81.5-1.51.61.81.41.51.51.8-2.5-2.7
Length with tail2.48.810.92.9-2.83.0-3.03.03.33.0-3.03.02.92.53.03.02.9-3.3-2.9
Length without tail2.45.27.32.7-2.42.5-2.72.42.52.3-2.32.31.81.92.32.32.0-2.1-1.6
Times rat made contact with spout0.50.61.30.7-0.30.7-0.70.70.90.7-0.70.70.71.10.70.71.0-0.6-0.7
Lifetime Intake5.36.08.8-2.41.8-2.32.5-2.4-2.3-2.42.4-2.4-2.4-2.9-2.3-2.3-2.53.03.0
Liver weight, left0.00.10.2-0.20.1-0.30.3-0.2-0.4-0.20.2-0.2-0.2-0.1-0.3-0.3-0.20.30.3
Liver weight, right0.00.10.2-0.30.3-0.30.3-0.3-0.4-0.20.2-0.2-0.1-0.2-0.4-0.40.20.2-0.0
Locomotor activity1.72.85.1-1.72.3-1.91.7-1.8-1.5-1.91.9-1.8-1.9-1.6-1.7-1.7-1.20.6-0.3
Locomotor testing distance2.44.18.1-2.22.8-2.42.1-2.1-1.9-2.22.2-2.2-2.3-1.8-2.1-2.1-1.20.7-0.5
Locomotor testing rearing2.13.26.2-2.12.5-2.22.0-1.9-1.7-1.81.8-1.7-2.0-1.6-2.0-2.0-1.10.9-0.1
Locomotion in novel chamber5.26.49.5-2.61.8-2.62.6-2.5-2.4-2.62.6-2.6-2.8-3.1-2.5-2.5-2.92.22.1
Locomotion in novel chamber post-restriction3.34.06.0-2.11.8-2.02.1-2.1-2.1-2.12.1-1.9-1.9-2.4-2.0-2.0-2.21.81.5
Fecal boli incidents, locomotor time 10.10.10.90.2-1.00.0-0.20.20.30.3-0.30.30.5-0.30.20.2-0.5-0.00.6
Change in fecal boli incidents, locomotor task0.10.10.50.00.50.1-0.10.0-0.0-0.20.2-0.2-0.4-0.0-0.1-0.10.70.3-0.2
Time >=10cm from walls, locomotor time 11.21.25.6-0.7-0.1-0.80.8-0.8-0.7-0.70.7-0.8-0.8-1.6-0.8-0.8-1.31.82.4
Bouts of movement, locomotor time 11.71.93.31.4-1.11.4-1.51.51.81.1-1.11.21.21.81.41.40.9-1.5-1.3
Total resting periods, locomotor time 11.11.22.31.2-1.01.2-1.21.31.50.9-0.91.01.01.51.11.10.6-1.2-0.8
Rest time, locomotor task time 11.31.42.2-1.31.0-1.31.3-1.1-0.9-1.41.4-1.3-1.4-1.5-1.2-1.2-1.30.60.4
Distance moved, locomotor task time 10.10.10.30.3-0.20.3-0.20.2-0.10.4-0.40.40.40.50.20.20.30.40.6
Vertical activity count, locomotor time 11.51.51.9-1.21.3-1.21.2-1.3-1.4-1.21.2-1.3-1.3-1.2-1.4-1.4-1.21.10.8
Time >=10cm from walls, locomotor time 20.10.10.40.1-0.60.1-0.10.30.40.4-0.40.30.1-0.00.30.3-0.20.00.4
Bouts of movement, locomotor time 20.50.50.90.8-0.50.9-0.90.70.90.6-0.60.60.81.00.70.70.6-0.7-0.6
Total resting periods, locomotor time 20.20.20.50.6-0.30.6-0.60.50.70.3-0.30.30.50.60.50.50.3-0.3-0.2
Rest time, locomotor task time 22.73.14.7-1.91.6-1.91.9-1.6-1.4-1.81.8-1.8-2.0-2.2-1.6-1.6-1.61.61.4
Distance moved, locomotor task time 21.31.52.51.2-1.11.3-1.21.21.11.3-1.31.31.21.61.21.21.1-1.2-1.0
Vertical activity count, locomotor time 20.20.21.60.00.50.1-0.1-0.2-0.2-0.00.0-0.1-0.10.3-0.2-0.20.2-0.8-1.3
Light reinforcement 10.10.10.4-0.50.7-0.40.5-0.5-0.2-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.1-0.3
Light reinforcement 20.91.22.6-1.30.3-1.21.3-1.0-1.0-0.90.9-1.0-1.0-1.4-1.0-1.0-1.60.81.1
Bone: marrow area1.12.46.7-1.40.6-1.41.5-1.4-1.8-1.31.3-1.2-1.3-1.4-1.4-1.4-1.52.32.6
Bone: maximum diameter0.20.32.00.5-1.40.5-0.40.60.30.6-0.60.60.6-0.20.50.5-0.2-0.30.3
Bone: maximum force3.15.39.42.6-3.12.6-2.52.52.32.4-2.42.52.32.12.52.51.8-1.00.1
Bone: maximum moment2.64.58.02.4-2.82.3-2.32.32.12.2-2.22.32.21.92.32.31.7-0.90.1
Mean time between licks in bursts0.60.92.31.0-0.21.0-1.00.71.00.5-0.50.60.71.00.80.81.5-1.1-1.5
Mean num. licks in bursts0.20.20.7-0.60.8-0.60.5-0.4-0.4-0.50.5-0.6-0.40.0-0.5-0.5-0.00.3-0.1
Cd content in liver1.21.32.8-1.20.7-1.21.2-1.2-1.2-1.11.1-1.1-0.9-1.7-1.1-1.1-1.60.60.6
Co content in liver1.21.44.4-1.32.1-1.31.2-1.3-1.1-1.31.3-1.2-1.2-0.8-1.1-1.1-0.60.0-0.9
Cu content in liver0.30.30.70.5-0.40.5-0.50.60.60.7-0.70.80.60.80.50.50.6-0.2-0.0
Fe content in liver0.10.20.50.3-0.70.3-0.30.40.50.5-0.50.50.60.10.30.30.1-0.3-0.1
K content in liver1.41.41.91.3-1.41.3-1.21.31.11.3-1.31.21.31.41.31.31.3-0.20.2
Mg content in liver0.20.21.30.3-0.20.2-0.20.30.10.2-0.20.20.10.70.20.20.30.91.2
Mn content in liver2.63.04.91.8-2.21.8-1.81.81.91.8-1.81.81.91.31.81.81.2-1.4-0.7
Na content in liver1.31.32.21.2-1.51.2-1.11.21.21.3-1.31.21.10.81.21.21.0-1.2-0.8
Rb content in liver1.82.33.0-1.51.6-1.51.5-1.5-1.6-1.61.6-1.6-1.5-0.9-1.6-1.6-1.21.71.4
Se content in liver0.10.20.9-0.1-0.7-0.10.1-0.00.00.0-0.00.00.1-0.5-0.1-0.1-0.80.40.9
Sr content in liver4.03.75.01.9-1.91.9-2.01.92.02.0-2.01.82.01.51.91.91.6-2.2-1.9
Zn content in liver1.31.42.21.3-1.11.2-1.21.21.21.5-1.51.51.21.41.21.21.0-0.7-0.4
Bone: minimum diameter1.12.06.6-1.20.6-1.21.3-1.2-1.7-1.11.1-1.0-1.2-0.9-1.3-1.3-1.32.32.6
Time in familiar zone, hab. session 10.40.40.7-0.50.4-0.50.5-0.6-0.6-0.50.5-0.5-0.5-0.6-0.7-0.7-0.50.80.8
Time in novel zone, hab. session 10.20.20.6-0.40.7-0.40.3-0.3-0.1-0.50.5-0.5-0.4-0.1-0.2-0.20.1-0.3-0.8
Total zone transitions, hab. session 10.70.91.51.0-0.91.0-1.01.01.01.2-1.21.20.91.10.90.90.9-0.5-0.3
Total locomotion distance, hab. session 10.30.51.3-0.60.5-0.70.7-0.6-0.6-0.40.4-0.4-0.7-0.4-0.7-0.7-0.51.11.2
Locomotion velocity, hab. session 10.10.10.6-0.10.0-0.20.2-0.1-0.20.1-0.10.1-0.20.1-0.2-0.2-0.10.60.7
Time in familiar zone, hab. session 20.10.10.80.00.5-0.00.0-0.2-0.2-0.10.1-0.10.1-0.1-0.2-0.20.5-0.4-0.9
Time in novel zone, hab. session 20.10.10.30.2-0.40.2-0.20.40.30.2-0.20.20.10.40.30.3-0.00.20.5
Total zone transitions, hab. session 21.41.83.11.3-1.21.3-1.31.41.31.6-1.61.61.21.81.41.41.4-0.00.3
Total locomotion distance, hab. session 20.10.21.3-0.10.1-0.10.10.0-0.20.2-0.20.2-0.20.4-0.0-0.00.21.11.1
Locomotion velocity, hab. session 20.20.32.1-0.30.1-0.30.4-0.2-0.4-0.10.1-0.1-0.40.1-0.2-0.2-0.11.31.5
Novel to familiar place preference ratio1.11.12.61.1-1.61.2-1.11.21.21.2-1.21.21.20.81.01.00.3-0.60.2
Novelty place preference0.50.51.30.7-1.10.7-0.70.80.80.8-0.80.80.80.50.60.60.0-0.30.3
Time in novel zone, NPP test0.40.40.90.6-1.00.6-0.60.70.70.7-0.70.70.70.50.50.50.0-0.20.3
Total zone transitions, NPP test2.53.54.81.9-1.91.9-1.92.02.02.2-2.22.21.81.92.02.01.8-1.0-0.5
Total locomotion distance, NPP test0.10.10.40.2-0.20.2-0.20.30.20.4-0.40.40.00.50.30.30.40.50.6
Locomotion velocity, NPP test0.10.10.30.3-0.30.3-0.30.40.30.4-0.40.40.10.60.30.30.40.40.6
Intraocular pressure0.91.23.4-1.10.5-1.11.0-1.0-0.5-1.41.4-1.4-1.1-1.5-1.0-1.0-1.80.20.4
Delta distance traveled before/after self-admin0.10.10.3-0.10.5-0.00.1-0.1-0.3-0.30.3-0.3-0.3-0.2-0.2-0.2-0.0-0.1-0.3
Delta ambulatory time before/after self-admin0.10.10.40.00.50.1-0.0-0.1-0.1-0.20.2-0.2-0.2-0.0-0.1-0.10.2-0.2-0.6
Parametrial fat weight2.65.08.4-2.11.7-2.12.2-2.2-2.5-2.12.1-2.1-2.0-2.0-2.2-2.2-2.32.92.9
Pavlov. Cond. lever latency0.30.30.6-0.60.8-0.60.5-0.6-0.5-0.60.6-0.6-0.6-0.5-0.7-0.7-0.50.0-0.2
Pavlov. Cond. magazine entry latency0.20.30.50.4-0.60.4-0.40.50.40.6-0.60.60.60.70.40.40.20.40.7
Pavlov. Cond. change in total contacts0.10.10.70.2-0.60.2-0.20.20.20.4-0.40.40.30.20.20.2-0.40.40.9
Pavlov. Cond. index score0.10.20.40.4-0.60.4-0.40.40.50.5-0.50.50.60.40.40.40.2-0.10.2
Pavlov. Cond. latency score0.10.10.20.2-0.40.3-0.20.30.30.4-0.40.40.40.40.30.30.20.10.3
Pavlov. Cond. lever contacts0.00.00.10.1-0.10.1-0.00.10.10.2-0.20.20.20.30.10.10.20.20.3
Pavlov. Cond. magazine entry number0.30.30.7-0.60.8-0.60.5-0.6-0.6-0.70.7-0.7-0.7-0.5-0.5-0.5-0.10.50.1
Pavlov. Cond. intertrial magazine entries0.50.61.3-0.70.8-0.80.7-0.9-0.9-0.80.8-0.8-0.8-1.0-0.8-0.8-1.20.40.3
Pavlov. Cond. lever-magazine prob. diff.0.40.40.80.6-0.90.6-0.60.70.70.8-0.80.80.80.70.60.60.4-0.20.1
Pavlov. Cond. response bias0.10.10.20.3-0.50.3-0.30.30.40.4-0.40.40.40.40.30.30.0-0.20.1
Pavlov. Cond. lever latency0.40.61.7-0.81.3-0.80.8-0.9-0.9-0.70.7-0.7-0.8-0.4-0.9-0.9-0.20.4-0.1
Pavlov. Cond. magazine entry latency3.54.05.12.1-2.12.1-2.12.12.12.2-2.22.22.32.12.02.01.8-1.3-0.7
Pavlov. Cond. change in total contacts1.72.35.11.6-2.31.6-1.61.71.61.6-1.61.71.71.21.61.60.5-0.80.2
Pavlov. Cond. index score2.32.95.21.8-2.31.9-1.81.91.81.8-1.81.91.91.51.81.81.1-1.0-0.2
Pavlov. Cond. latency score1.82.24.31.6-2.11.6-1.61.71.61.6-1.61.61.71.31.61.60.9-0.8-0.1
Pavlov. Cond. lever contacts0.50.71.60.9-1.30.9-0.80.91.00.8-0.80.80.80.30.90.90.3-0.8-0.4
Pavlov. Cond. magazine entry number6.47.89.8-3.03.1-3.03.0-3.0-3.0-3.03.0-3.0-3.0-2.7-2.8-2.8-2.32.01.1
Pavlov. Cond. intertrial magazine entries1.21.51.9-1.41.1-1.31.4-1.3-1.3-1.41.4-1.3-1.3-1.3-1.1-1.1-1.21.00.8
Pavlov. Cond. lever-magazine prob. diff.2.83.65.82.0-2.42.0-2.02.12.02.0-2.02.12.11.72.02.01.3-1.2-0.4
Pavlov. Cond. response bias1.82.54.11.7-2.01.7-1.71.71.81.6-1.61.61.71.21.71.71.0-1.2-0.6
Time in closed arm before self-admin0.10.10.40.2-0.70.1-0.10.40.10.2-0.20.20.20.10.20.2-0.30.10.5
Time in closed arm after self-admin0.10.10.2-0.00.5-0.00.0-0.3-0.2-0.20.2-0.2-0.4-0.2-0.3-0.30.10.40.2
Time in open arm before self-admin0.60.73.0-0.91.7-0.70.8-1.2-0.7-0.80.8-0.8-0.80.1-0.8-0.80.10.4-0.4
Time in open arm after self-admin0.20.20.4-0.50.6-0.50.4-0.5-0.4-0.40.4-0.4-0.2-0.0-0.4-0.4-0.2-0.3-0.6
Bone: periosteal estimation0.10.31.9-0.1-0.7-0.20.3-0.1-0.5-0.10.1-0.0-0.1-0.5-0.2-0.2-0.60.81.4
Bone: periosteal perimeter0.10.21.00.3-1.00.3-0.20.30.00.4-0.40.50.3-0.00.20.2-0.20.30.8
Bone: post-yield work0.91.39.80.7-1.70.7-0.50.60.20.6-0.60.70.30.60.70.7-0.41.93.1
Progressive ratio test 1 active lever presses3.63.84.9-2.11.7-2.02.1-1.9-2.0-2.02.0-2.0-2.0-2.2-1.9-1.9-2.01.71.5
Progressive ratio test 1 breakpoint3.23.44.4-2.01.6-1.92.0-1.8-1.9-1.91.9-1.9-1.9-2.1-1.8-1.8-1.91.51.3
Progressive ratio test 1 inactive lever presses1.51.62.1-1.31.5-1.41.3-1.3-1.2-1.31.3-1.3-1.3-1.3-1.3-1.3-1.11.20.9
Progressive ratio test 2 active lever presses5.56.09.0-2.51.8-2.42.5-2.5-2.3-2.52.5-2.5-2.5-3.0-2.4-2.4-2.72.22.2
Progressive ratio test 2 breakpoint6.67.410.8-2.92.2-2.72.8-2.8-2.7-2.82.8-2.8-2.8-3.3-2.7-2.7-3.02.22.0
Progressive ratio test 2 inactive lever presses10.211.716.1-3.42.8-3.53.5-3.6-3.1-3.43.4-3.4-3.5-4.0-3.4-3.4-3.83.33.1
Incentive Sensitization - Responses0.70.71.2-0.80.4-0.70.7-0.9-0.7-0.90.9-0.9-0.8-1.1-0.8-0.8-1.10.91.1
Incentive Sensitization - Breakpoint1.01.11.7-1.00.5-0.90.9-1.1-0.9-1.11.1-1.1-1.0-1.3-1.0-1.0-1.31.01.2
Sum of active levers in priming session hrs 5-61.81.74.21.3-2.01.3-1.31.31.61.2-1.21.21.20.41.21.20.4-1.8-1.1
Progressive ratio2.22.53.71.6-1.91.5-1.51.71.71.8-1.81.81.71.81.71.71.4-0.10.6
Food seeking constrained by brief footshock0.20.20.60.50.00.5-0.60.30.40.2-0.20.30.40.60.30.30.7-0.5-0.8
Seeking ratio, punishment vs. effort1.92.34.9-1.52.2-1.41.4-1.7-1.7-1.71.7-1.7-1.6-1.4-1.6-1.6-1.00.2-0.7
Retroperitoneal fat weight6.220.425.3-4.54.0-4.54.6-4.6-5.0-4.64.6-4.6-4.6-4.3-4.6-4.6-4.54.43.9
Reaction time number correct0.40.51.10.5-0.70.6-0.50.90.90.5-0.50.50.60.50.80.80.7-1.1-1.0
Reaction time mean minus median3.14.17.32.2-2.72.1-2.22.12.42.1-2.12.02.11.62.12.11.4-1.4-0.5
Reaction time mean minus median AUC1.72.23.71.5-1.91.5-1.61.61.81.5-1.51.41.51.11.61.61.1-1.4-0.8
Reaction time num false alarms0.30.51.7-0.41.3-0.40.4-0.8-0.7-0.80.8-0.8-0.8-0.1-0.7-0.70.30.2-0.5
Reaction time num false alarms AUC0.10.20.80.30.70.2-0.3-0.10.1-0.10.1-0.1-0.10.50.00.00.9-0.3-0.8
Reaction time trials correct on left0.40.51.10.5-0.70.6-0.50.90.90.5-0.50.50.60.50.80.80.7-1.1-1.0
Reaction time trials on left0.50.71.40.6-0.80.7-0.61.01.00.6-0.60.60.70.60.90.90.8-1.2-1.2
Reaction time mean0.10.10.30.2-0.50.4-0.30.30.50.2-0.20.10.10.20.30.3-0.3-0.10.3
Reaction time mean AUC0.10.10.30.2-0.50.3-0.20.20.40.2-0.20.0-0.00.10.20.2-0.40.10.5
Median of all reaction times0.10.10.4-0.3-0.0-0.00.2-0.1-0.0-0.30.3-0.4-0.4-0.1-0.2-0.2-0.60.30.6
Reaction time omissions1.21.63.21.3-1.31.3-1.41.51.81.1-1.11.11.11.51.31.31.1-1.1-0.8
Reaction time false alarm rate0.30.41.3-0.31.2-0.40.4-0.9-0.7-0.60.6-0.6-0.7-0.1-0.7-0.70.20.5-0.1
Reaction time premature initiation rate2.93.86.61.9-1.21.9-1.81.81.81.9-1.92.01.92.11.91.92.6-2.1-2.4
Reaction time premature initiations4.66.49.62.4-1.82.4-2.42.52.52.4-2.42.52.52.52.52.53.0-2.9-3.1
Std. dev. reaction times0.81.22.31.2-1.51.2-1.21.21.41.1-1.11.01.00.81.21.20.6-0.8-0.2
Reaction time trials completed0.50.71.40.6-0.80.7-0.61.01.00.6-0.60.60.70.60.90.90.8-1.2-1.2
Reaction time trials AUC0.30.40.90.4-0.50.5-0.50.80.70.4-0.40.40.50.40.60.60.7-0.9-1.0
Run reversals in cocaine runway, females0.40.41.30.6-0.00.5-0.60.60.40.6-0.60.60.60.90.60.61.10.50.4
Run reversals in cocaine runway, males0.30.30.7-0.50.5-0.50.5-0.6-0.6-0.60.6-0.6-0.4-0.8-0.5-0.5-0.5-0.4-0.7
Latency to leave start box in cocaine runway0.10.21.2-0.00.1-0.20.1-0.2-0.4-0.10.1-0.1-0.2-0.0-0.2-0.2-0.30.91.1
Latency to leave start box in cocaine runway, F0.10.10.40.1-0.0-0.2-0.10.0-0.20.2-0.20.20.20.30.00.0-0.10.50.6
Latency to leave start box in cocaine runway, M0.10.10.20.0-0.10.0-0.0-0.1-0.1-0.30.3-0.3-0.3-0.2-0.2-0.2-0.10.40.5
Std. dev. time between licks in bursts0.20.20.9-0.10.8-0.10.1-0.3-0.2-0.50.5-0.5-0.4-0.0-0.2-0.20.4-0.3-0.9
Total sessions with >9 infusions2.42.64.1-1.51.5-1.61.6-1.5-1.6-1.61.6-1.6-1.7-1.9-1.5-1.5-1.42.01.8
Short access day 1 total inactive lever presses4.65.16.4-2.12.3-2.22.1-2.1-2.0-2.52.5-2.5-2.5-2.4-2.3-2.3-2.22.21.8
Short access day 10 total inactive lever presses3.84.27.0-2.02.6-2.12.0-2.1-1.9-2.22.2-2.2-2.2-2.1-2.2-2.2-1.71.70.9
Short access day 1 total infusions3.84.07.0-2.01.7-1.92.0-1.7-2.2-2.02.0-2.0-2.0-2.0-1.8-1.8-1.72.72.5
Short access day 10 total infusions2.52.88.1-1.51.0-1.51.5-1.4-1.5-1.41.4-1.4-1.5-1.7-1.4-1.4-1.42.72.8
Short access total infusions2.02.34.8-1.51.2-1.31.5-1.3-1.5-1.41.4-1.4-1.5-1.6-1.3-1.3-1.22.22.1
Short access day 1 locomotion3.23.45.8-1.81.7-1.81.8-1.8-1.8-1.71.7-1.7-1.8-2.1-1.8-1.8-1.52.42.2
Short access day 10 total locomotion2.22.54.9-1.61.4-1.71.6-1.4-1.5-1.51.5-1.5-1.4-1.5-1.5-1.5-1.42.22.1
Short access total locomotion1.92.04.2-1.51.3-1.31.5-1.2-1.2-1.31.3-1.3-1.4-1.4-1.3-1.3-1.12.11.9
One hour access (0.3 mA shock)11.813.820.0-3.93.2-3.83.9-3.8-3.6-3.73.7-3.7-3.8-4.5-3.7-3.7-3.93.22.8
Compulsive drug intake3.43.46.41.7-0.81.7-1.71.81.21.8-1.81.81.82.51.71.72.2-2.1-2.4
One hour access (shock baseline)10.812.620.1-3.62.4-3.63.6-3.6-3.1-3.63.6-3.6-3.6-4.5-3.5-3.5-4.03.23.2
Social response proportion1.01.11.61.3-1.31.1-1.31.01.21.2-1.21.11.00.81.11.10.9-0.9-0.5
Social responses0.30.40.80.7-0.50.7-0.70.50.70.5-0.50.60.70.60.40.40.7-0.9-0.9
Social time0.40.61.30.6-0.60.6-0.60.80.80.6-0.60.60.70.80.70.70.9-1.1-1.1
Soleus weight4.312.615.2-3.73.5-3.73.8-3.7-3.9-3.73.7-3.6-3.8-3.4-3.7-3.7-3.33.02.3
Bone: stiffness2.64.17.22.2-2.72.2-2.12.22.02.2-2.22.32.01.82.22.21.5-0.80.2
Tibialis anterior weight11.639.746.16.5-6.76.5-6.56.66.86.6-6.66.56.55.56.66.65.9-5.7-4.4
Time to tail flick, vehicle, before self-admin0.50.51.00.6-1.00.5-0.60.60.80.9-0.90.90.80.60.70.70.7-0.10.3
Time to tail flick, vehicle, after self-admin1.31.42.61.1-1.11.0-1.10.81.01.3-1.31.31.61.51.31.31.6-0.4-0.3
Time to tail flick, test, before self-admin1.01.02.5-0.91.0-1.01.0-0.9-1.0-0.90.9-0.9-0.9-0.7-0.8-0.8-0.51.61.4
Time to tail flick, test, after self-admin0.00.00.10.1-0.20.1-0.10.00.20.0-0.00.00.20.20.20.20.1-0.3-0.4
Delta time to tail flick, vehicle, before/after SA0.40.40.80.7-0.40.6-0.60.50.50.5-0.50.50.80.90.70.70.9-0.3-0.3
Delta time to tail flick, test, before/after SA1.91.74.71.1-1.31.2-1.20.81.31.2-1.21.21.21.21.21.20.9-2.2-2.0
Tibia length1.13.07.91.8-2.81.8-1.81.91.91.6-1.61.81.90.81.81.80.6-1.7-0.6
Ambulatory time before self-admin0.40.41.60.7-1.30.7-0.70.70.70.6-0.60.60.70.20.70.70.1-0.40.2
Ambulatory time after self-admin0.20.20.8-0.1-0.1-0.10.10.2-0.4-0.40.4-0.4-0.3-0.6-0.3-0.3-0.70.60.9
Bone: tissue strength0.10.00.20.2-0.40.2-0.20.10.2-0.00.0-0.0-0.00.10.40.4-0.20.00.3
Total heroin consumption6.37.49.72.8-2.72.9-2.82.82.82.8-2.82.82.93.12.82.82.5-2.2-1.7
Bone: trabecular number0.40.61.60.8-1.30.8-0.70.70.50.9-0.91.00.80.70.50.50.30.30.9
Bone: trabecular spacing0.20.31.0-0.61.0-0.50.5-0.5-0.3-0.50.5-0.6-0.6-0.3-0.3-0.3-0.00.1-0.4
Bone: trabecular thickness0.70.91.8-0.80.6-0.80.9-0.9-1.1-0.80.8-0.8-0.9-0.7-1.0-1.0-0.91.31.3
Bone: trabecular tissue density3.44.85.8-2.32.1-2.32.3-2.4-2.3-2.22.2-2.2-2.3-2.3-2.3-2.3-2.41.61.2
Water consumed over 24 hours1.01.21.71.0-0.61.0-1.11.11.31.0-1.01.11.11.21.11.11.1-1.3-1.3
Number of responses in last shaping day1.41.52.3-1.41.5-1.41.3-1.2-1.1-1.31.3-1.3-1.3-1.3-1.3-1.3-1.00.70.2