Hub : Genes

Pinx1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Pinx1 0.06 0.04 3.0e-03 0.01 0.03 0.03 0.03 1.3e-01 7.9e-03 7.9e-03 1.6e-02
2 Adipose gene expression Pinx1 0.15 0.09 1.6e-14 0.1 0.12 0.12 0.11 2.3e-11 5.4e-13 1.0e-12 3.0e-12
3 Brain gene expression Pinx1 0.11 0.07 6.0e-05 0.04 0.05 0.04 0.05 2.7e-04 2.1e-05 1.3e-04 2.3e-05
4 RMTg gene expression Pinx1 0.15 0.13 7.3e-03 0.03 0.07 0.02 0.05 6.2e-02 5.4e-03 9.1e-02 1.5e-02
5 Liver gene expression Pinx1 0.11 0.07 6.7e-09 0.06 0.06 0.06 0.06 5.2e-07 2.7e-07 1.5e-07 1.8e-07
6 pVTA alternative polyA XM_006252181.4 0.06 0.04 9.1e-03 0.02 0.04 0.02 0.03 3.8e-02 5.7e-03 4.6e-02 3.0e-02
7 PL gene expression Pinx1 0.08 0.05 2.3e-06 0.07 0.04 0.06 0.06 9.5e-08 1.1e-05 6.6e-07 1.8e-07
8 Liver intron excision ratio chr15_38101332_38101735 0.03 0.03 3.5e-03 0.02 0.02 0.01 0.01 2.6e-03 6.4e-03 1.4e-02 1.6e-02
9 pVTA alternative polyA XM_039093330.1 0.1 0.06 5.8e-04 0.05 0.08 0.06 0.07 2.9e-03 2.1e-04 1.6e-03 4.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.50.92.20.30.5-0.70.8-0.21.3-0.71.5-1.3
Area under the delay curve2.22.38.0-2.60.91.61.0-1.30.1-0.4-2.80.4
BMI with tail0.82.66.2-2.31.21.81.3-2.50.6-1.4-1.8-0.3
BMI without tail0.30.51.11.0-0.9-0.8-0.90.4-0.80.6-0.10.7
Body weight1.35.38.0-2.82.62.62.5-2.82.0-2.0-0.9-1.7
Weight adjusted by age2.62.94.8-1.22.21.51.8-1.52.1-1.61.0-2.1
Bone surface0.40.71.60.00.6-0.50.80.01.3-0.51.2-1.2
Bone volume0.20.41.1-0.20.6-0.50.8-0.11.0-0.50.6-0.9
Breakpoint value in progressive ratio session0.40.42.3-0.5-0.5-0.1-0.1-0.3-0.60.2-1.50.8
Number of licking bursts0.30.30.9-0.7-0.30.4-0.1-0.7-0.6-0.1-0.90.6
Context. condit. distance diff. score3.23.86.21.3-1.9-2.0-2.30.9-2.22.5-1.82.3
Locomotion velocity, session 10.50.51.0-0.70.50.21.0-0.70.8-0.90.2-0.7
Locomotion distance, session 10.50.61.2-0.30.5-0.21.1-0.01.1-1.00.8-1.0
Locomotion velocity, session 20.81.02.1-1.30.70.11.3-1.11.0-1.4-0.0-0.8
Locomotion distance, session 21.31.83.4-0.40.8-0.41.7-0.51.7-1.81.8-1.7
Locomotion velocity, session 31.11.22.1-1.11.11.11.3-1.51.1-1.00.1-1.1
Locomotion distance, session 30.20.20.5-0.50.30.60.6-0.70.3-0.0-0.3-0.2
Stereotopy head waving bouts, day 30.30.42.00.7-0.20.3-0.20.4-0.0-0.61.4-0.3
Stereotopy head waving duration, day 30.70.92.2-0.70.81.40.8-0.70.7-1.50.6-0.9
Locomotion velocity, session 71.21.44.51.3-1.1-2.1-0.90.4-0.71.6-0.40.9
Locomotion distance, session 72.12.75.71.9-1.8-2.4-1.71.1-1.42.0-0.21.4
Stereotopy head waving bouts, day 72.02.23.0-1.71.51.51.7-1.61.5-1.6-0.1-1.4
Stereotopy head waving duration, day 72.32.74.9-1.81.92.21.7-1.71.5-1.7-0.4-1.4
Locomotion velocity, session 80.20.20.8-0.60.2-0.30.4-0.90.2-0.4-0.70.0
Locomotion distance, session 80.20.31.90.3-0.6-1.4-0.3-0.1-0.30.3-0.20.4
Degree of sensitization distance4.94.99.92.5-2.5-3.1-2.42.1-2.02.10.11.9
Degree of sensitization stereotypy1.31.42.6-1.61.31.21.2-1.31.0-0.9-1.1-0.8
Conditioned locomotion0.70.81.40.7-0.6-0.8-1.20.7-0.91.1-0.71.0
Cocaine response after cond. corrected4.14.67.60.7-1.7-0.6-2.51.4-2.72.7-2.82.7
Cocaine response after cond. not corrected3.33.66.20.6-1.5-0.3-2.21.3-2.42.5-2.42.4
Cocaine response before conditioning1.21.42.4-0.61.10.61.5-0.71.5-1.31.3-1.5
Saline control response0.10.10.40.1-0.30.20.30.30.0-0.70.5-0.2
Bone: connectivity density0.81.35.61.10.4-0.90.30.21.2-0.52.4-1.5
Bone: cortical apparent density1.31.73.70.5-0.90.3-1.50.9-1.71.9-1.51.7
Bone: cortical area0.30.52.5-1.00.00.50.2-0.3-0.40.4-1.60.7
Bone: cortical porosity2.42.64.2-2.01.61.81.6-2.01.3-1.9-0.4-1.1
Bone: cortical porosity1.31.42.6-1.61.21.41.2-1.30.9-1.4-0.5-0.8
Bone: cortical thickness0.61.04.2-1.40.01.00.3-0.7-0.60.4-2.10.9
Bone: cortical thickness1.61.96.7-0.6-1.2-0.4-0.60.1-1.61.4-2.62.0
Bone: cortical tissue density1.41.83.80.5-0.90.3-1.50.9-1.71.9-1.51.7
Condit. Reinf. active minus inactive responses1.51.72.8-0.81.20.51.7-1.01.7-1.51.1-1.6
Condit. Reinf. active-inactive response ratio0.10.10.60.3-0.00.10.00.10.1-0.20.8-0.2
Condit. Reinf. active responses1.41.73.0-1.11.20.51.7-1.11.6-1.60.7-1.5
Condit. Reinf. inactive responses0.40.50.9-0.80.80.31.0-0.40.9-0.90.1-0.8
Incentive salience index mean3.34.06.4-2.12.11.42.5-2.12.3-2.20.6-2.0
Condit. Reinf. lever presses3.44.56.7-2.52.31.62.6-2.42.3-2.10.1-1.9
Condit. Reinf. active minus inactive responses0.20.20.50.4-0.7-0.7-0.30.4-0.40.10.40.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.0-0.2-0.40.2-0.40.1-0.30.3-0.1
Condit. Reinf. active responses0.20.30.80.5-0.6-0.9-0.50.5-0.40.30.30.4
Condit. Reinf. inactive responses0.70.91.61.2-0.9-1.3-0.91.3-0.70.80.30.6
Condit. Reinf. lever presses2.12.95.1-0.81.40.51.8-1.42.0-2.22.3-2.0
Condit. Reinf. lever reinforcers received0.00.10.30.1-0.3-0.5-0.10.0-0.1-0.10.30.1
Conditioned reinforcement - actives7.67.613.13.6-2.7-3.1-2.93.5-2.22.91.21.8
Conditioned reinforcement - inactives0.70.81.71.3-0.8-1.0-0.61.2-0.20.41.3-0.1
Conditioned locomotion5.46.59.02.4-2.7-2.1-3.02.6-2.92.9-0.82.8
Patch foraging indifference point 0 sec0.71.22.0-0.41.10.51.2-0.11.4-1.31.4-1.4
Patch foraging indifference point AUC2.12.44.11.0-1.9-1.0-1.61.2-2.01.7-1.32.0
Delay disc. indifference point, 0s delay0.00.00.1-0.30.10.10.10.10.00.1-0.20.1
Delay disc. indifference point, 16s delay1.71.78.5-1.80.11.10.0-0.2-0.80.4-2.91.2
Delay disc. indifference point, 2s delay0.20.20.8-0.90.40.60.5-0.30.2-0.3-0.5-0.0
Delay disc. indifference point, 24s delay1.91.910.1-1.9-0.00.90.2-0.6-0.70.3-3.21.2
Delay disc. indifference point, 4s delay2.72.87.1-2.71.51.91.5-2.00.8-1.2-2.1-0.4
Delay disc. indifference point, 8s delay2.72.88.6-2.71.11.91.1-1.70.2-0.5-2.90.3
Indifference point function ln k1.72.44.5-1.52.11.51.5-1.41.8-1.50.6-1.7
Indifference point function log k1.72.44.5-1.52.11.51.5-1.41.8-1.50.6-1.7
Patch foraging total patch changes 0 sec0.81.31.9-0.71.30.91.2-0.31.4-1.31.1-1.3
Patch foraging total patch changes 12 sec0.10.10.2-0.1-0.2-0.20.5-0.10.2-0.50.1-0.1
Patch foraging total patch changes 18 sec1.51.93.01.4-1.3-1.2-1.41.7-1.41.6-0.71.4
Patch foraging total patch changes 24 sec0.00.10.40.2-0.10.00.00.60.0-0.10.3-0.1
Patch foraging total patch changes 6 sec0.00.00.10.3-0.2-0.1-0.10.1-0.20.10.20.1
Patch foraging time to switch 0 sec0.00.00.2-0.0-0.3-0.50.0-0.10.0-0.3-0.2-0.0
Patch foraging water rate 0 sec0.50.71.8-1.01.21.40.9-0.60.7-0.6-0.2-0.6
Patch foraging water rate 12 sec0.30.40.9-0.81.00.90.7-0.30.6-0.3-0.0-0.5
Patch foraging water rate 18 sec1.82.44.6-2.12.02.21.4-1.81.2-1.2-0.4-0.9
Patch foraging water rate 24 sec0.10.10.7-0.40.2-0.2-0.0-0.10.00.5-0.80.2
Patch foraging water rate 6 sec0.40.72.9-0.81.11.70.6-0.00.5-0.5-0.0-0.4
Seeking ratio, delayed vs. immediate footshock0.10.20.40.10.6-0.1-0.10.60.40.60.2-0.3
Distance traveled before self-admin0.20.20.80.70.2-0.0-0.30.90.00.40.8-0.1
Distance traveled after self-admin0.30.30.70.5-0.1-0.1-0.80.8-0.50.7-0.30.5
Extensor digitorum longus weight3.313.127.6-5.34.05.33.1-4.12.1-2.1-3.0-1.5
Bone: elastic displacement0.20.20.60.5-0.5-0.2-0.10.7-0.2-0.40.50.1
Bone: elastic work0.50.71.3-0.80.60.81.1-0.10.9-1.20.4-0.9
Bone: endosteal estimation0.10.20.50.00.4-0.40.40.20.7-0.30.6-0.7
Bone: endosteal perimeter0.20.51.80.60.2-0.90.10.80.6-0.21.3-0.7
Epididymis fat weight0.20.51.00.6-0.7-0.5-0.61.0-0.70.8-0.50.8
Delta time in closed arm before/after self-admin0.10.10.20.20.4-0.2-0.20.20.30.30.4-0.3
Delta time in open arm before/after self-admin0.30.30.50.7-0.7-0.1-0.40.5-0.60.50.50.5
Diff in mean of infusions in LGA sessions2.02.33.4-1.81.41.71.7-1.61.3-1.7-0.8-1.1
Delay discount exponential model param2.62.78.62.8-1.0-1.7-1.11.6-0.20.52.9-0.4
Extinction: sum of active levers before priming0.60.60.80.6-0.9-0.9-0.80.7-0.80.8-0.30.8
Active lever presses in extinction session 60.30.31.00.7-0.7-1.0-0.40.4-0.30.50.40.3
Bone: final force0.40.71.9-1.40.90.70.8-0.70.40.1-1.3-0.1
Bone: final moment0.50.81.9-1.41.10.91.0-0.80.7-0.2-0.9-0.4
Food consumed during 24 hour testing period0.30.30.6-0.30.60.40.6-0.20.7-0.70.7-0.8
Glucose0.10.10.3-0.3-0.5-0.40.1-0.5-0.30.0-0.50.5
Heart weight0.20.20.50.60.2-0.4-0.40.70.10.70.4-0.1
Delay discount hyperbolic model param2.72.88.42.9-1.0-1.9-1.21.7-0.30.82.7-0.2
Intermittent access intake day 1-15 change0.40.41.20.9-0.6-1.1-0.30.60.00.40.5-0.1
Intermittent access intake escalation0.50.51.41.1-0.9-1.2-0.50.6-0.40.50.20.2
Intermittent access intake escalation 20.30.30.70.8-0.7-0.7-0.60.7-0.40.50.30.2
Intermitt. access day 1 inactive lever presses0.50.52.61.0-0.5-0.6-0.30.4-0.00.21.6-0.2
Intermitt. access day 15 inactive lever presses1.11.22.6-0.31.01.00.8-0.91.1-1.11.6-1.4
Intermitt. access escalation Index0.60.61.20.6-1.1-1.1-0.60.3-0.70.5-0.70.8
Intermittent access day 1 total infusions1.11.22.20.6-1.4-0.6-1.20.9-1.50.9-1.01.4
Intermittent access day 15 total infusions2.02.34.41.6-2.1-1.8-1.51.4-1.61.2-0.21.4
Intermittent access terminal intake (last 3 days)1.51.73.91.3-2.0-1.4-1.40.9-1.50.9-0.21.3
Intermittent access total infusions2.52.84.41.4-2.1-1.6-1.81.4-2.01.5-0.91.9
Intermittent access day 1 locomotion0.20.30.9-0.3-0.40.2-0.30.1-0.60.2-1.00.7
Intermittent access day 15 total locomotion1.11.22.21.1-1.5-0.8-1.21.1-1.40.9-0.11.2
Intermittent access total locomotion0.30.40.80.2-0.9-0.2-0.70.2-0.90.3-0.50.9
Intermittent access standard deviation0.20.30.70.5-0.6-0.8-0.10.5-0.0-0.20.8-0.1
Left kidney weight1.95.39.5-1.63.11.92.7-2.13.0-1.80.7-2.8
Right kidney weight1.85.210.2-1.63.22.42.4-1.82.8-1.71.1-2.7
Cocaine induced anxiety0.30.40.7-0.30.70.30.8-0.20.8-0.80.1-0.8
Post-drug Anxiety2.32.54.6-0.61.80.91.8-1.12.1-1.71.3-2.1
Baseline Anxiety0.40.50.6-0.70.70.60.7-0.60.8-0.70.5-0.8
Tail length0.31.02.61.6-0.3-1.0-0.61.30.10.81.5-0.4
Length with tail0.52.03.6-0.91.91.21.6-0.91.9-1.01.0-1.9
Length without tail3.27.110.8-3.33.13.12.9-2.92.6-2.4-0.3-2.3
Times rat made contact with spout0.40.40.8-0.30.5-0.30.8-0.70.9-0.60.5-0.8
Lifetime Intake2.52.84.11.6-2.0-1.7-1.91.8-1.91.6-0.51.7
Liver weight, left1.21.93.5-1.81.71.91.3-1.61.1-0.8-1.0-0.9
Liver weight, right0.60.92.4-1.60.51.50.7-0.90.0-1.0-1.30.1
Locomotor activity3.35.28.3-2.12.92.32.7-1.62.7-2.20.6-2.5
Locomotor testing distance1.52.55.1-0.41.70.71.9-0.02.2-1.51.8-2.3
Locomotor testing rearing3.65.613.30.01.80.22.4-0.23.1-2.63.6-3.3
Locomotion in novel chamber0.50.71.2-1.00.90.80.8-1.10.8-0.70.1-0.7
Locomotion in novel chamber post-restriction0.10.20.6-0.50.0-0.50.7-0.30.5-0.2-0.1-0.3
Fecal boli incidents, locomotor time 10.30.31.80.0-0.3-0.4-0.30.2-0.40.6-1.40.5
Change in fecal boli incidents, locomotor task0.70.71.5-0.20.60.30.8-0.90.9-1.01.2-1.0
Time >=10cm from walls, locomotor time 11.11.12.60.21.00.11.1-0.11.5-0.81.6-1.6
Bouts of movement, locomotor time 10.50.51.1-0.80.7-0.10.9-1.10.9-0.5-0.5-0.6
Total resting periods, locomotor time 10.20.20.9-0.40.1-0.60.3-0.60.20.2-0.90.1
Rest time, locomotor task time 10.40.42.4-0.40.2-0.30.2-0.90.10.2-1.60.2
Distance moved, locomotor task time 10.50.62.00.8-0.6-0.2-0.51.2-0.50.21.40.2
Vertical activity count, locomotor time 10.40.41.20.2-0.20.9-0.21.1-0.4-0.21.10.0
Time >=10cm from walls, locomotor time 20.50.61.40.31.00.30.50.21.1-0.31.0-1.2
Bouts of movement, locomotor time 21.11.24.0-1.70.70.90.9-1.40.3-0.5-2.00.1
Total resting periods, locomotor time 21.71.85.3-2.00.91.11.1-1.80.4-0.7-2.3-0.0
Rest time, locomotor task time 21.01.25.4-1.30.10.10.8-1.60.0-0.3-2.30.4
Distance moved, locomotor task time 20.50.62.40.8-0.3-0.0-0.81.6-0.40.41.10.1
Vertical activity count, locomotor time 20.80.93.30.6-0.60.5-1.11.8-1.00.70.20.8
Light reinforcement 10.30.50.7-0.60.70.10.8-0.90.8-0.80.1-0.7
Light reinforcement 20.60.81.50.6-0.7-0.6-1.20.6-1.01.2-0.51.0
Bone: marrow area0.10.20.50.10.3-0.50.30.30.7-0.30.6-0.6
Bone: maximum diameter0.30.51.8-0.4-0.5-0.0-0.40.3-0.80.6-1.31.0
Bone: maximum force0.40.82.4-1.50.70.80.9-0.60.40.1-1.50.0
Bone: maximum moment0.50.82.4-1.50.91.01.1-0.60.7-0.2-1.0-0.4
Mean time between licks in bursts1.82.56.32.5-1.0-1.7-1.61.9-0.61.51.90.2
Mean num. licks in bursts0.40.51.10.70.5-0.70.40.50.90.01.0-0.9
Cd content in liver0.20.20.90.30.1-0.30.20.00.5-0.51.0-0.7
Co content in liver0.70.94.9-1.10.10.2-0.2-0.6-0.50.4-2.20.8
Cu content in liver1.51.93.5-1.41.30.61.5-1.91.5-1.70.3-1.4
Fe content in liver0.30.41.50.70.0-0.50.10.00.5-0.41.2-0.7
K content in liver0.90.91.80.3-1.0-0.5-1.30.5-1.30.8-0.81.3
Mg content in liver1.01.01.80.9-1.1-0.9-1.30.9-1.20.9-0.21.1
Mn content in liver1.51.72.61.2-1.3-1.4-1.61.4-1.41.6-0.41.3
Na content in liver8.08.513.7-3.32.83.33.1-3.12.6-3.70.7-2.5
Rb content in liver0.70.92.01.4-1.0-0.9-1.20.9-0.80.80.70.6
Se content in liver0.30.30.8-0.40.50.30.5-0.20.6-0.90.7-0.7
Sr content in liver0.80.83.61.2-0.3-0.90.00.50.5-0.31.9-0.7
Zn content in liver3.94.36.4-2.12.32.02.1-2.12.1-2.50.6-2.1
Bone: minimum diameter0.10.20.8-0.90.40.20.7-0.20.4-0.4-0.5-0.1
Time in familiar zone, hab. session 10.70.71.00.5-0.9-0.9-0.70.7-0.81.0-0.70.9
Time in novel zone, hab. session 10.60.61.7-0.90.41.30.8-1.00.3-1.0-0.3-0.3
Total zone transitions, hab. session 10.10.10.5-0.60.20.20.50.10.2-0.2-0.70.0
Total locomotion distance, hab. session 10.10.10.60.1-0.3-0.30.20.8-0.0-0.00.20.1
Locomotion velocity, hab. session 10.10.20.4-0.20.2-0.10.60.50.5-0.40.3-0.4
Time in familiar zone, hab. session 20.90.91.40.7-0.9-0.6-1.11.0-1.01.2-1.01.0
Time in novel zone, hab. session 20.70.71.7-0.60.40.01.1-0.90.8-1.30.8-0.8
Total zone transitions, hab. session 20.70.91.5-1.11.20.61.1-0.81.2-0.7-0.2-1.0
Total locomotion distance, hab. session 20.20.30.5-0.60.60.00.7-0.40.7-0.4-0.2-0.5
Locomotion velocity, hab. session 20.50.61.2-1.00.90.31.1-0.71.0-0.7-0.3-0.7
Novel to familiar place preference ratio0.20.30.80.2-0.5-0.90.4-0.00.2-0.60.7-0.2
Novelty place preference0.40.40.80.1-0.2-0.90.7-0.20.6-0.80.9-0.5
Time in novel zone, NPP test0.50.51.0-0.0-0.0-0.70.9-0.30.8-1.01.0-0.7
Total zone transitions, NPP test0.30.41.0-0.60.8-0.10.8-0.31.0-0.40.2-0.8
Total locomotion distance, NPP test0.60.82.70.8-0.1-1.40.20.70.7-0.01.6-0.8
Locomotion velocity, NPP test0.50.72.10.9-0.2-1.40.10.80.60.11.4-0.6
Intraocular pressure1.31.84.91.8-1.6-1.9-0.61.2-0.4-0.12.2-0.0
Delta distance traveled before/after self-admin0.20.20.6-0.6-0.10.20.2-0.8-0.1-0.4-0.70.2
Delta ambulatory time before/after self-admin0.20.20.6-0.1-0.6-0.2-0.2-0.0-0.50.1-0.80.5
Parametrial fat weight3.97.610.42.6-3.1-3.2-2.93.2-2.63.0-0.52.5
Pavlov. Cond. lever latency1.31.73.01.7-1.5-0.9-1.31.7-1.31.10.61.0
Pavlov. Cond. magazine entry latency1.21.62.3-1.31.41.11.4-1.51.3-1.4-0.1-1.2
Pavlov. Cond. change in total contacts3.33.65.9-2.42.01.62.3-2.21.8-2.1-0.4-1.5
Pavlov. Cond. index score3.74.87.7-2.72.62.02.3-2.82.1-2.0-0.7-1.8
Pavlov. Cond. latency score3.14.06.6-2.42.31.62.1-2.62.1-1.8-0.5-1.7
Pavlov. Cond. lever contacts3.03.55.9-2.22.31.42.0-2.42.0-1.7-0.3-1.7
Pavlov. Cond. magazine entry number2.42.94.72.0-1.9-1.6-1.92.2-1.71.80.31.5
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.00.60.30.20.40.5-0.20.5-0.5
Pavlov. Cond. lever-magazine prob. diff.4.25.28.5-2.82.72.22.4-2.92.2-2.0-0.8-1.8
Pavlov. Cond. response bias3.03.66.0-2.42.32.01.9-2.51.8-1.7-0.7-1.5
Pavlov. Cond. lever latency3.75.07.31.9-2.3-1.8-2.42.2-2.42.7-1.82.4
Pavlov. Cond. magazine entry latency1.72.03.8-1.91.61.71.4-1.61.1-1.3-0.3-1.0
Pavlov. Cond. change in total contacts2.94.06.5-2.02.12.62.1-2.01.8-2.30.9-1.8
Pavlov. Cond. index score3.34.25.7-2.32.22.32.2-2.11.9-2.40.8-1.9
Pavlov. Cond. latency score3.54.35.6-2.22.22.32.2-2.12.0-2.41.0-2.0
Pavlov. Cond. lever contacts3.44.77.4-1.72.11.62.4-2.02.4-2.72.0-2.4
Pavlov. Cond. magazine entry number0.70.81.91.4-1.0-0.9-0.91.0-0.70.80.20.5
Pavlov. Cond. intertrial magazine entries3.24.211.43.1-1.9-3.4-1.42.2-0.51.22.10.3
Pavlov. Cond. lever-magazine prob. diff.2.93.75.1-2.22.12.32.0-2.01.8-2.20.7-1.7
Pavlov. Cond. response bias3.24.47.0-2.22.11.82.4-2.12.1-2.61.2-2.0
Time in closed arm before self-admin2.52.84.9-1.82.02.21.6-2.01.4-1.3-0.8-1.2
Time in closed arm after self-admin1.41.54.1-1.32.01.21.1-0.91.4-0.3-0.9-1.1
Time in open arm before self-admin0.50.62.00.7-0.7-1.4-0.31.1-0.10.10.8-0.0
Time in open arm after self-admin0.70.72.31.2-0.9-0.8-0.60.9-0.40.41.50.1
Bone: periosteal estimation0.00.10.2-0.30.0-0.20.10.20.00.2-0.50.2
Bone: periosteal perimeter0.00.00.1-0.20.1-0.30.20.20.20.00.0-0.1
Bone: post-yield work3.24.37.60.5-2.1-1.4-1.81.4-2.42.5-2.72.8
Progressive ratio test 1 active lever presses1.01.12.00.4-1.4-0.9-0.90.4-1.30.8-1.21.4
Progressive ratio test 1 breakpoint1.11.12.20.4-1.5-1.0-0.90.4-1.40.8-1.21.4
Progressive ratio test 1 inactive lever presses0.80.81.91.4-1.1-0.9-0.81.2-0.70.50.80.4
Progressive ratio test 2 active lever presses2.32.44.32.1-2.0-2.0-1.61.3-1.41.40.51.2
Progressive ratio test 2 breakpoint1.21.42.71.6-1.5-1.7-1.20.9-0.91.00.60.7
Progressive ratio test 2 inactive lever presses0.91.02.31.5-1.2-1.3-0.90.9-0.60.61.10.3
Incentive Sensitization - Responses1.41.44.12.0-0.9-1.3-0.91.0-0.30.71.9-0.1
Incentive Sensitization - Breakpoint1.31.44.52.0-0.8-1.3-0.70.8-0.10.52.1-0.3
Sum of active levers in priming session hrs 5-61.01.01.31.1-1.1-1.1-1.00.9-1.01.1-0.10.9
Progressive ratio0.40.41.4-0.70.61.20.5-0.50.4-0.80.1-0.6
Food seeking constrained by brief footshock1.41.72.90.8-1.1-0.3-1.60.7-1.71.6-1.61.7
Seeking ratio, punishment vs. effort0.70.81.40.6-0.7-0.6-1.00.5-1.11.2-1.01.2
Retroperitoneal fat weight1.13.54.81.7-2.0-2.2-1.92.0-1.82.1-1.11.9
Reaction time number correct0.20.32.00.60.0-0.60.00.10.4-0.11.4-0.5
Reaction time mean minus median0.70.91.7-0.90.60.61.1-1.01.0-1.30.7-1.0
Reaction time mean minus median AUC0.50.61.0-0.50.60.50.8-0.80.9-1.00.9-1.0
Reaction time num false alarms1.62.13.4-1.21.70.91.7-1.51.8-1.50.7-1.7
Reaction time num false alarms AUC1.11.52.5-1.01.50.81.4-1.11.6-1.20.6-1.5
Reaction time trials correct on left0.20.32.00.60.0-0.60.00.10.4-0.11.4-0.5
Reaction time trials on left0.30.42.30.8-0.0-0.7-0.00.20.30.01.5-0.5
Reaction time mean0.10.10.80.20.10.10.0-0.00.3-0.10.9-0.5
Reaction time mean AUC0.20.31.20.00.50.50.2-0.00.5-0.31.1-0.8
Median of all reaction times0.10.10.70.4-0.1-0.1-0.40.4-0.00.30.8-0.2
Reaction time omissions1.31.75.41.9-0.7-1.6-1.01.2-0.10.82.3-0.3
Reaction time false alarm rate0.91.21.8-1.31.41.01.2-1.21.1-0.9-0.4-1.0
Reaction time premature initiation rate0.10.10.5-0.5-0.00.10.4-0.50.0-0.2-0.70.1
Reaction time premature initiations0.00.00.1-0.1-0.1-0.30.2-0.30.1-0.10.1-0.0
Std. dev. reaction times0.10.10.5-0.0-0.1-0.20.2-0.30.2-0.40.7-0.4
Reaction time trials completed0.30.42.30.8-0.0-0.7-0.00.20.30.01.5-0.5
Reaction time trials AUC0.30.52.40.8-0.1-0.7-0.10.30.40.01.6-0.5
Run reversals in cocaine runway, females0.10.10.40.2-0.2-0.2-0.20.7-0.10.10.30.1
Run reversals in cocaine runway, males2.12.04.7-2.20.71.61.5-1.90.6-1.9-0.9-0.4
Latency to leave start box in cocaine runway0.60.72.11.3-0.5-1.0-0.41.0-0.10.51.4-0.0
Latency to leave start box in cocaine runway, F0.20.21.40.3-0.1-0.10.30.10.3-0.41.2-0.4
Latency to leave start box in cocaine runway, M0.90.82.21.5-0.2-0.8-0.91.1-0.20.71.5-0.1
Std. dev. time between licks in bursts0.60.82.71.3-0.4-0.8-0.51.20.00.31.7-0.3
Total sessions with >9 infusions1.31.42.41.6-1.1-0.9-1.31.5-0.91.11.20.7
Short access day 1 total inactive lever presses0.30.40.90.5-0.8-0.9-0.50.7-0.50.50.00.5
Short access day 10 total inactive lever presses0.50.51.00.9-0.9-1.0-0.70.5-0.60.60.80.4
Short access day 1 total infusions2.42.53.71.7-1.8-1.7-1.91.7-1.61.60.71.3
Short access day 10 total infusions0.80.92.60.0-1.1-0.4-0.60.7-1.20.5-1.61.3
Short access total infusions0.80.91.50.7-1.2-0.9-1.11.2-1.10.9-0.31.0
Short access day 1 locomotion0.50.61.80.8-0.1-0.2-1.01.4-0.40.90.60.2
Short access day 10 total locomotion0.70.81.4-1.10.91.20.8-1.20.7-0.80.1-0.7
Short access total locomotion0.20.20.4-0.40.40.60.2-0.20.3-0.40.6-0.5
One hour access (0.3 mA shock)1.92.23.81.1-2.0-1.6-1.41.3-1.71.2-1.21.7
Compulsive drug intake0.10.10.5-0.50.2-0.10.4-0.50.2-0.2-0.7-0.0
One hour access (shock baseline)2.32.64.31.7-2.1-1.7-1.71.8-1.81.4-0.21.6
Social response proportion1.71.85.11.8-1.4-2.3-1.21.1-0.71.40.90.6
Social responses1.51.95.81.8-1.3-2.4-1.01.4-0.41.11.60.3
Social time1.82.35.30.01.60.01.4-0.62.2-1.02.3-2.3
Soleus weight0.41.34.5-0.4-0.20.7-0.90.3-1.31.3-2.11.4
Bone: stiffness0.50.71.8-1.31.10.90.7-1.00.60.0-0.9-0.3
Tibialis anterior weight4.515.331.1-5.64.35.33.5-4.72.6-2.8-2.6-2.0
Time to tail flick, vehicle, before self-admin1.91.92.9-1.71.21.61.6-1.61.1-1.7-0.5-1.0
Time to tail flick, vehicle, after self-admin0.80.81.9-1.20.40.90.9-1.40.3-1.1-0.9-0.2
Time to tail flick, test, before self-admin0.50.51.2-0.30.50.20.70.10.8-0.81.1-0.9
Time to tail flick, test, after self-admin1.51.62.91.7-1.3-1.7-1.21.3-0.70.81.50.3
Delta time to tail flick, vehicle, before/after SA0.30.30.90.6-0.5-0.9-0.60.3-0.40.5-0.00.4
Delta time to tail flick, test, before/after SA1.61.42.61.6-1.2-1.3-1.41.1-1.01.30.60.8
Tibia length3.911.017.0-2.33.62.43.8-2.84.1-3.52.6-4.1
Ambulatory time before self-admin0.10.10.40.30.3-0.1-0.30.6-0.00.50.00.1
Ambulatory time after self-admin0.20.20.7-0.10.20.4-0.40.3-0.40.4-0.80.5
Bone: tissue strength0.40.31.80.8-0.3-0.20.00.70.1-0.11.3-0.4
Total heroin consumption0.10.10.4-0.30.10.70.2-0.7-0.1-0.5-0.20.1
Bone: trabecular number0.40.72.30.50.2-0.90.40.11.0-0.51.5-1.1
Bone: trabecular spacing1.01.34.1-0.8-0.31.3-0.60.2-1.30.9-2.01.4
Bone: trabecular thickness1.01.11.7-1.21.10.51.3-1.31.2-1.1-0.3-1.0
Bone: trabecular tissue density0.60.93.9-1.20.62.00.3-0.5-0.3-0.4-1.20.4
Water consumed over 24 hours1.31.52.0-1.31.41.31.4-1.21.3-1.30.2-1.2
Number of responses in last shaping day0.20.30.80.2-0.6-0.1-0.50.9-0.60.30.10.5