Hub : Genes

Pinx1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Pinx1 0.06 0.05 5.9e-03 0.02 0.03 0.04 0.03 2.6e-02 6.5e-03 3.9e-03 9.0e-03
2 Brain gene expression Pinx1 0.1 0.06 4.9e-05 0.04 0.06 0.04 0.04 1.7e-04 4.7e-06 3.1e-04 6.2e-05
3 Liver gene expression Pinx1 0.09 0.05 5.2e-08 0.04 0.06 0.06 0.06 6.9e-05 7.4e-07 6.2e-07 8.1e-07
4 PL isoform ratio XM_006252181.5 0.03 0.02 3.0e-03 0 0.02 0 0.01 1.0e-01 3.1e-03 1.1e-01 3.1e-02
5 pVTA gene expression Pinx1 0.11 0.06 3.4e-08 0.06 0.07 0.06 0.07 1.1e-05 1.4e-06 6.1e-06 2.9e-06
6 Adipose gene expression Pinx1 0.17 0.11 2.8e-15 0.11 0.12 0.12 0.11 1.2e-12 1.5e-13 9.3e-14 1.6e-12
7 Liver intron excision ratio chr15_42277237_42277640 0.03 0.02 4.3e-03 0.02 0.02 0 0.01 3.5e-03 6.5e-03 8.6e-02 1.6e-02
8 PL gene expression Pinx1 0.09 0.06 1.2e-06 0.05 0.04 0.04 0.04 2.0e-06 5.8e-05 2.4e-05 1.2e-05
9 Liver mRNA stability Pinx1 0.03 0.03 1.5e-03 0.01 0.01 0.01 0.01 2.1e-02 1.5e-02 4.8e-02 1.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.34.00.7-0.8-0.1-1.60.1-0.51.7-0.82.0
Area under the delay curve3.04.611.7-2.22.2-1.73.41.4-0.7-3.0-0.7-2.1
BMI with tail0.51.74.2-1.21.3-2.11.41.2-1.6-0.9-0.8-0.2
BMI without tail0.00.10.20.2-0.2-0.4-0.3-0.00.00.40.10.4
Body weight1.04.28.0-2.52.4-2.81.32.5-2.5-0.3-1.80.8
Weight adjusted by age0.82.44.1-2.01.5-1.9-0.21.8-1.80.9-1.51.4
Bone surface0.51.13.30.5-0.60.0-1.40.2-0.91.5-0.81.8
Bone volume0.30.51.80.3-0.5-0.1-0.80.2-0.80.9-0.61.3
Breakpoint value in progressive ratio session0.40.61.5-1.20.8-0.61.20.60.5-0.7-0.4-0.9
Number of licking bursts0.20.61.8-0.90.4-0.30.80.01.3-0.80.1-1.1
Context. condit. distance diff. score2.73.37.01.5-1.81.40.8-2.12.2-1.62.7-1.7
Locomotion velocity, session 10.40.41.2-0.60.4-0.70.10.90.30.6-1.10.5
Locomotion distance, session 10.40.51.5-0.30.1-0.3-0.50.8-0.21.2-1.01.1
Locomotion velocity, session 20.60.71.5-0.80.4-1.20.51.10.80.5-1.20.6
Locomotion distance, session 21.41.95.8-0.4-0.1-0.8-1.31.10.52.4-1.72.1
Locomotion velocity, session 30.81.02.1-1.41.1-1.20.11.4-0.10.4-1.10.7
Locomotion distance, session 30.10.20.3-0.50.5-0.40.50.5-0.1-0.30.1-0.2
Stereotopy head waving bouts, day 30.40.52.0-0.0-0.00.4-1.4-0.10.01.2-0.60.6
Stereotopy head waving duration, day 30.50.61.5-1.20.9-0.4-0.60.70.00.7-1.10.3
Locomotion velocity, session 71.31.43.21.5-1.80.60.0-1.21.8-0.21.6-0.0
Locomotion distance, session 72.02.65.02.0-2.21.5-0.5-2.01.8-0.12.1-0.4
Stereotopy head waving bouts, day 71.51.74.5-2.11.5-1.60.31.7-0.90.2-1.40.7
Stereotopy head waving duration, day 71.92.35.9-2.42.0-1.70.61.9-1.5-0.2-1.40.4
Locomotion velocity, session 80.20.20.8-0.30.0-0.50.70.30.9-0.30.0-0.2
Locomotion distance, session 80.40.63.10.6-1.00.1-0.1-0.41.80.30.40.2
Degree of sensitization distance4.24.58.92.8-3.02.2-1.1-2.72.30.32.3-0.4
Degree of sensitization stereotypy1.21.34.0-2.01.3-1.31.21.3-0.5-0.7-0.5-0.1
Conditioned locomotion1.01.23.21.0-1.11.00.3-1.40.4-1.01.8-0.9
Cocaine response after cond. corrected2.84.28.81.2-0.81.61.7-2.10.5-3.02.8-2.9
Cocaine response after cond. not corrected2.23.27.21.0-0.51.41.6-1.80.0-2.72.4-2.7
Cocaine response before conditioning1.21.52.7-0.90.8-1.1-0.71.4-1.21.4-1.61.5
Saline control response0.40.61.6-0.50.50.2-0.90.70.21.3-1.10.6
Bone: connectivity density1.62.67.01.2-1.10.4-2.6-0.2-0.52.5-0.72.5
Bone: cortical apparent density0.71.13.20.20.40.61.1-0.6-0.3-1.71.2-1.8
Bone: cortical area0.50.82.6-0.80.8-0.61.60.5-0.5-1.3-0.1-1.1
Bone: cortical porosity1.31.42.6-1.61.5-1.31.41.2-0.7-1.0-0.9-0.4
Bone: cortical porosity1.11.22.8-1.71.4-1.11.11.3-0.8-0.7-1.0-0.1
Bone: cortical thickness1.01.74.9-1.31.2-0.92.20.70.3-1.7-0.0-1.7
Bone: cortical thickness2.12.67.30.00.3-0.12.7-0.21.5-2.41.0-2.6
Bone: cortical tissue density0.71.13.20.30.30.61.1-0.7-0.3-1.71.3-1.8
Condit. Reinf. active minus inactive responses0.91.02.0-1.00.6-1.1-0.31.4-0.41.1-1.21.3
Condit. Reinf. active-inactive response ratio0.10.10.20.3-0.00.3-0.5-0.0-0.00.40.00.3
Condit. Reinf. active responses0.91.12.4-1.30.8-1.30.01.5-0.20.9-1.31.1
Condit. Reinf. inactive responses0.40.51.4-1.20.6-0.90.21.0-0.10.4-0.90.6
Incentive salience index mean2.22.95.7-2.01.7-2.40.62.4-1.10.6-2.11.2
Condit. Reinf. lever presses2.63.99.1-2.42.0-3.01.22.6-1.40.1-2.30.9
Condit. Reinf. active minus inactive responses0.20.31.21.1-0.70.7-0.3-0.60.60.20.1-0.2
Condit. Reinf. active-inactive response ratio0.10.10.30.6-0.3-0.1-0.4-0.10.60.5-0.30.3
Condit. Reinf. active responses0.30.41.41.2-0.90.7-0.3-0.80.30.10.3-0.1
Condit. Reinf. inactive responses0.50.81.71.3-1.31.2-0.6-1.10.60.30.8-0.0
Condit. Reinf. lever presses1.42.04.3-0.50.4-1.3-1.21.2-0.42.0-2.12.1
Condit. Reinf. lever reinforcers received0.10.10.50.7-0.50.3-0.2-0.40.40.3-0.1-0.0
Conditioned reinforcement - actives1.14.39.83.1-2.52.6-1.8-2.50.70.82.10.1
Conditioned reinforcement - inactives0.51.54.50.8-0.91.0-2.1-0.50.82.1-0.01.1
Conditioned locomotion2.94.37.92.8-1.72.30.5-2.51.6-1.72.5-2.1
Patch foraging indifference point 0 sec0.41.12.2-0.50.6-0.7-0.81.1-1.01.4-1.51.4
Patch foraging indifference point AUC0.71.62.51.5-0.91.20.6-1.41.3-1.31.4-1.6
Delay disc. indifference point, 0s delay0.10.10.50.40.20.00.50.0-0.7-0.60.0-0.2
Delay disc. indifference point, 16s delay2.23.08.5-1.61.3-0.52.90.5-0.2-2.90.1-2.4
Delay disc. indifference point, 2s delay0.40.51.0-0.30.9-0.61.00.6-0.8-0.9-0.4-0.5
Delay disc. indifference point, 24s delay2.13.410.3-1.11.2-0.93.20.50.5-3.20.1-2.5
Delay disc. indifference point, 4s delay3.53.77.0-2.62.3-2.12.41.9-1.0-1.7-1.5-1.0
Delay disc. indifference point, 8s delay2.64.410.6-2.42.2-1.93.31.5-0.5-2.9-0.6-2.0
Indifference point function ln k0.51.63.9-1.31.4-1.60.41.5-2.00.2-1.30.8
Indifference point function log k0.51.63.9-1.31.4-1.60.41.5-2.00.2-1.30.8
Patch foraging total patch changes 0 sec0.41.22.5-0.81.1-1.0-0.31.3-1.41.0-1.61.1
Patch foraging total patch changes 12 sec0.20.30.8-0.50.2-0.3-0.00.60.90.6-0.80.2
Patch foraging total patch changes 18 sec0.40.91.81.2-0.91.30.1-1.20.6-0.51.1-0.9
Patch foraging total patch changes 24 sec0.00.10.20.20.20.3-0.20.1-0.30.3-0.50.0
Patch foraging total patch changes 6 sec0.10.10.50.20.1-0.1-0.20.10.70.4-0.20.0
Patch foraging time to switch 0 sec0.10.21.4-0.5-0.3-0.1-0.3-0.01.20.5-0.10.2
Patch foraging water rate 0 sec0.20.93.5-0.61.2-0.70.90.9-1.9-0.7-0.5-0.2
Patch foraging water rate 12 sec0.10.52.0-0.60.9-0.40.70.7-1.4-0.5-0.3-0.1
Patch foraging water rate 18 sec1.02.34.9-1.62.0-1.51.51.5-2.2-1.1-0.8-0.4
Patch foraging water rate 24 sec0.20.30.6-0.60.0-0.10.80.1-0.4-0.80.8-0.3
Patch foraging water rate 6 sec0.81.15.7-0.51.4-0.20.80.8-2.4-0.7-0.5-0.5
Seeking ratio, delayed vs. immediate footshock0.20.31.70.2-0.20.10.2-0.2-1.3-0.50.70.3
Distance traveled before self-admin0.20.53.50.70.10.4-0.5-0.1-1.90.10.10.5
Distance traveled after self-admin0.71.24.40.10.7-0.21.3-0.1-2.1-1.70.4-0.9
Extensor digitorum longus weight4.216.729.3-5.35.4-4.54.64.1-3.9-3.0-2.6-1.9
Bone: elastic displacement0.30.41.20.4-0.40.9-0.8-0.21.10.9-0.10.3
Bone: elastic work0.30.51.4-0.50.8-0.2-0.21.0-0.10.7-1.20.5
Bone: endosteal estimation0.20.51.60.3-0.40.1-0.80.2-0.90.8-0.41.3
Bone: endosteal perimeter0.41.02.30.9-0.90.5-1.4-0.3-1.01.3-0.31.5
Epididymis fat weight0.20.92.20.50.10.81.1-0.5-0.7-1.50.6-1.4
Delta time in closed arm before/after self-admin0.20.21.00.2-0.3-0.20.1-0.4-1.0-0.50.50.2
Delta time in open arm before/after self-admin0.10.10.3-0.00.50.0-0.00.30.50.1-0.6-0.2
Diff in mean of infusions in LGA sessions1.63.08.3-2.92.1-1.90.92.3-0.40.0-2.00.4
Delay discount exponential model param3.95.312.72.5-2.52.1-3.6-1.70.63.11.02.1
Extinction: sum of active levers before priming0.10.10.4-0.60.30.10.40.10.2-0.2-0.1-0.5
Active lever presses in extinction session 60.30.30.91.0-0.60.30.1-0.60.5-0.00.5-0.3
Bone: final force0.61.02.4-1.01.0-1.11.61.1-0.8-1.1-0.5-0.4
Bone: final moment0.61.01.4-1.11.1-1.11.21.2-1.1-0.7-0.80.0
Food consumed during 24 hour testing period0.10.30.6-0.30.3-0.1-0.60.5-0.70.6-0.70.8
Glucose0.20.31.6-0.30.2-0.10.70.11.2-0.4-0.1-0.8
Heart weight0.20.40.70.8-0.70.7-0.3-0.8-0.4-0.20.8-0.1
Delay discount hyperbolic model param3.54.510.42.3-2.32.0-3.2-1.60.62.71.11.9
Intermittent access intake day 1-15 change0.21.22.41.1-1.31.2-1.2-1.11.60.80.80.3
Intermittent access intake escalation0.10.61.40.7-0.80.7-0.9-0.71.20.70.40.2
Intermittent access intake escalation 20.20.41.30.5-0.60.6-0.6-0.71.20.20.5-0.1
Intermitt. access day 1 inactive lever presses0.00.61.31.1-0.60.3-1.2-0.20.11.00.31.0
Intermitt. access day 15 inactive lever presses0.21.22.30.00.7-1.0-1.10.8-1.41.5-1.01.3
Intermitt. access escalation Index0.00.10.40.4-0.40.0-0.1-0.10.60.30.20.2
Intermittent access day 1 total infusions0.20.61.41.2-0.71.1-0.1-1.10.1-0.30.8-1.0
Intermittent access day 15 total infusions0.71.72.91.6-1.51.5-1.1-1.51.70.71.0-0.3
Intermittent access terminal intake (last 3 days)1.01.84.21.5-1.51.6-1.1-1.52.00.80.9-0.4
Intermittent access total infusions1.92.33.81.9-1.71.8-0.7-1.91.80.11.5-0.9
Intermittent access day 1 locomotion0.10.20.8-0.10.5-0.10.6-0.0-0.3-0.6-0.1-0.9
Intermittent access day 15 total locomotion0.31.02.01.4-0.81.4-0.5-1.31.1-0.00.9-0.9
Intermittent access total locomotion0.20.30.70.8-0.30.6-0.1-0.70.4-0.20.3-0.8
Intermittent access standard deviation0.21.15.10.4-1.00.9-1.1-0.62.31.20.10.2
Left kidney weight0.53.97.9-1.82.0-2.50.22.4-2.80.6-2.01.8
Right kidney weight1.06.916.8-2.42.7-3.10.13.1-4.10.8-2.52.3
Cocaine induced anxiety0.41.21.9-1.11.3-1.40.91.3-1.3-0.4-1.10.1
Post-drug Anxiety1.51.74.6-1.01.4-1.4-0.11.5-2.10.6-1.51.0
Baseline Anxiety0.10.20.5-0.40.20.0-0.60.2-0.10.7-0.40.4
Tail length0.21.33.9-0.0-0.10.2-1.80.4-0.52.0-0.71.8
Length with tail0.52.23.6-1.81.3-1.2-0.61.9-1.21.3-1.61.8
Length without tail0.94.810.1-3.22.7-2.61.72.7-2.0-0.8-1.90.4
Times rat made contact with spout0.30.31.0-0.2-0.1-0.8-0.30.60.40.6-0.61.0
Lifetime Intake1.62.03.31.7-1.61.7-0.7-1.81.70.21.3-0.8
Liver weight, left1.22.14.6-1.91.7-1.30.21.7-2.10.3-1.60.7
Liver weight, right0.71.32.3-1.21.5-0.41.50.8-0.8-1.3-0.6-1.3
Locomotor activity2.94.57.5-2.52.4-2.30.52.7-2.70.7-2.41.4
Locomotor testing distance0.92.24.6-0.70.8-0.7-1.21.5-1.81.9-1.72.1
Locomotor testing rearing1.65.915.8-0.60.3-0.8-2.91.9-1.34.0-2.54.0
Locomotion in novel chamber0.40.51.2-1.10.7-1.00.11.0-0.10.4-0.80.5
Locomotion in novel chamber post-restriction0.20.53.2-0.8-0.1-0.40.60.51.80.1-0.10.1
Fecal boli incidents, locomotor time 10.10.20.50.1-0.30.10.6-0.30.2-0.70.6-0.4
Change in fecal boli incidents, locomotor task0.50.51.7-0.40.1-0.3-0.90.50.41.3-0.81.0
Time >=10cm from walls, locomotor time 10.91.13.3-0.30.2-0.3-1.30.9-0.71.7-0.91.8
Bouts of movement, locomotor time 10.40.51.8-0.90.1-1.00.40.71.30.2-0.60.5
Total resting periods, locomotor time 10.50.53.8-0.3-0.3-0.50.70.11.9-0.30.1-0.1
Rest time, locomotor task time 10.30.63.5-0.1-0.5-0.60.7-0.11.9-0.40.5-0.2
Distance moved, locomotor task time 10.10.31.00.5-0.11.0-0.8-0.3-0.80.5-0.00.1
Vertical activity count, locomotor time 10.10.85.2-0.10.80.9-0.40.1-2.30.0-0.5-0.3
Time >=10cm from walls, locomotor time 20.20.62.10.10.1-0.0-0.90.4-1.40.8-0.21.2
Bouts of movement, locomotor time 20.51.63.7-1.51.3-1.31.91.10.2-1.5-0.7-0.9
Total resting periods, locomotor time 20.52.14.5-1.81.5-1.62.11.30.4-1.6-1.0-1.0
Rest time, locomotor task time 21.11.96.3-1.50.5-1.21.90.92.5-1.0-0.5-1.1
Distance moved, locomotor task time 20.60.73.20.7-0.21.2-0.8-0.7-1.80.00.70.1
Vertical activity count, locomotor time 20.61.57.40.90.21.4-0.1-0.9-2.7-1.00.8-0.9
Light reinforcement 10.10.51.3-0.90.6-0.90.10.9-0.30.4-1.10.6
Light reinforcement 20.20.51.00.6-0.60.70.3-1.00.1-0.80.9-0.9
Bone: marrow area0.20.41.50.3-0.50.1-0.80.1-0.70.8-0.31.2
Bone: maximum diameter0.20.51.5-0.10.20.21.2-0.1-0.3-1.20.4-1.1
Bone: maximum force0.61.33.3-1.01.2-1.11.81.1-0.9-1.3-0.6-0.7
Bone: maximum moment0.71.32.0-1.11.3-1.11.41.3-1.4-0.9-0.9-0.3
Mean time between licks in bursts0.42.54.92.0-1.91.6-2.2-1.60.21.31.11.3
Mean num. licks in bursts0.30.72.30.9-0.6-0.0-0.90.1-1.11.0-0.31.5
Cd content in liver2.42.76.1-1.31.1-1.0-1.31.8-0.92.0-2.52.1
Co content in liver0.80.92.1-1.40.9-1.11.40.7-0.3-1.0-0.4-0.7
Cu content in liver1.11.33.5-1.40.9-1.90.41.4-0.60.4-1.31.0
Fe content in liver0.70.92.40.7-0.90.9-1.5-0.50.61.3-0.01.0
K content in liver0.30.30.90.7-0.60.4-0.2-0.9-0.1-0.40.8-0.4
Mg content in liver1.11.22.61.6-1.51.1-1.3-1.20.30.80.80.7
Mn content in liver0.80.92.01.4-1.31.1-0.6-1.3-0.20.11.2-0.0
Na content in liver4.95.610.2-3.23.1-2.91.12.9-1.80.1-3.10.3
Rb content in liver0.80.92.51.1-0.80.8-1.6-0.60.41.3-0.01.0
Se content in liver0.20.30.9-0.40.2-0.1-0.70.2-0.90.6-0.50.7
Sr content in liver1.21.02.70.4-0.3-0.1-1.60.2-0.51.7-0.91.6
Zn content in liver0.70.82.10.4-0.5-0.0-1.4-0.0-0.61.3-0.71.5
Bone: minimum diameter0.20.30.6-0.40.5-0.60.70.7-0.7-0.3-0.6-0.1
Time in familiar zone, hab. session 10.40.40.70.8-0.80.50.5-0.80.4-0.50.8-0.7
Time in novel zone, hab. session 10.60.71.8-1.31.3-0.60.41.00.7-0.1-0.8-0.3
Total zone transitions, hab. session 10.20.30.9-0.50.4-0.21.00.50.3-0.5-0.0-0.5
Total locomotion distance, hab. session 10.10.10.60.4-0.20.30.20.10.70.2-0.1-0.1
Locomotion velocity, hab. session 10.10.10.20.10.1-0.10.00.5-0.10.4-0.40.4
Time in familiar zone, hab. session 20.60.61.40.5-0.61.00.2-1.00.8-0.71.2-0.8
Time in novel zone, hab. session 20.50.51.2-0.50.2-0.7-0.30.80.31.1-1.10.8
Total zone transitions, hab. session 20.50.61.6-1.30.7-1.10.51.0-0.80.1-0.50.6
Total locomotion distance, hab. session 20.20.20.6-0.60.2-0.80.60.6-0.4-0.1-0.20.3
Locomotion velocity, hab. session 20.40.51.2-1.00.6-1.10.70.9-0.5-0.2-0.50.3
Novel to familiar place preference ratio0.50.62.20.6-0.8-0.0-0.6-0.01.51.2-0.40.7
Novelty place preference0.60.72.00.4-0.7-0.3-0.80.21.31.4-0.71.1
Time in novel zone, NPP test0.70.82.30.2-0.5-0.4-0.80.41.31.5-0.81.2
Total zone transitions, NPP test0.20.20.7-0.3-0.0-0.80.10.6-0.50.3-0.40.8
Total locomotion distance, NPP test0.91.22.91.0-1.30.2-1.5-0.30.41.70.11.7
Locomotion velocity, NPP test0.81.12.41.1-1.40.3-1.3-0.40.41.50.31.5
Intraocular pressure2.64.29.21.9-2.02.0-3.0-1.21.92.9-0.11.7
Delta distance traveled before/after self-admin0.70.71.7-0.90.8-0.71.30.50.6-1.1-0.3-1.0
Delta ambulatory time before/after self-admin0.30.51.4-0.40.5-0.21.10.10.8-1.00.1-1.2
Parametrial fat weight1.33.17.91.7-2.42.0-1.2-1.82.80.81.50.2
Pavlov. Cond. lever latency1.41.85.11.5-1.32.3-1.2-1.51.20.51.3-0.3
Pavlov. Cond. magazine entry latency0.81.02.3-1.31.1-1.50.31.3-0.30.3-1.30.6
Pavlov. Cond. change in total contacts2.83.05.8-2.22.0-2.41.42.3-0.8-0.1-2.10.2
Pavlov. Cond. index score3.24.19.5-2.52.3-3.11.62.4-1.7-0.5-2.00.4
Pavlov. Cond. latency score2.63.38.3-2.22.0-2.91.32.2-1.4-0.3-1.90.5
Pavlov. Cond. lever contacts1.92.36.5-1.81.5-2.61.31.7-1.2-0.4-1.50.4
Pavlov. Cond. magazine entry number2.12.65.62.3-1.92.4-1.0-2.10.80.11.7-0.4
Pavlov. Cond. intertrial magazine entries0.20.21.7-0.10.10.0-0.10.2-1.30.1-0.10.4
Pavlov. Cond. lever-magazine prob. diff.3.54.410.1-2.62.4-3.21.72.5-1.8-0.7-2.00.3
Pavlov. Cond. response bias2.12.65.6-2.11.9-2.41.51.8-1.2-0.8-1.4-0.0
Pavlov. Cond. lever latency2.33.37.91.7-1.51.90.8-2.11.2-1.82.8-1.9
Pavlov. Cond. magazine entry latency1.01.43.9-2.01.6-1.31.01.4-0.5-0.4-1.1-0.1
Pavlov. Cond. change in total contacts1.12.65.0-2.02.2-1.70.32.1-1.40.6-2.10.6
Pavlov. Cond. index score1.72.75.1-2.22.0-1.80.32.1-1.20.6-2.30.8
Pavlov. Cond. latency score1.72.85.1-2.22.0-1.90.22.0-1.40.7-2.30.9
Pavlov. Cond. lever contacts2.23.27.6-1.81.6-1.9-0.72.1-1.11.8-2.71.8
Pavlov. Cond. magazine entry number0.40.61.61.3-0.90.8-0.8-0.80.10.40.60.2
Pavlov. Cond. intertrial magazine entries2.65.610.03.1-3.22.1-3.1-2.01.52.41.02.1
Pavlov. Cond. lever-magazine prob. diff.1.62.44.6-2.12.0-1.80.51.9-1.10.3-2.10.4
Pavlov. Cond. response bias2.02.86.0-2.21.8-1.90.02.1-0.81.1-2.41.2
Time in closed arm before self-admin0.81.43.7-1.01.5-1.50.91.2-1.9-0.7-0.70.1
Time in closed arm after self-admin1.11.35.4-0.70.5-1.11.20.3-2.3-1.50.60.2
Time in open arm before self-admin0.60.81.40.3-1.10.9-1.1-0.61.11.20.20.7
Time in open arm after self-admin0.60.62.10.1-0.10.3-1.20.10.71.5-0.90.7
Bone: periosteal estimation0.00.10.6-0.10.1-0.10.40.2-0.8-0.3-0.10.1
Bone: periosteal perimeter0.00.10.40.0-0.1-0.10.00.1-0.60.1-0.20.3
Bone: post-yield work2.54.39.11.2-1.01.52.3-1.71.3-2.92.6-3.0
Progressive ratio test 1 active lever presses0.40.83.70.6-0.90.8-0.3-0.81.90.40.5-0.5
Progressive ratio test 1 breakpoint0.40.63.20.5-0.70.7-0.1-0.71.80.20.4-0.7
Progressive ratio test 1 inactive lever presses0.41.02.71.1-0.70.7-1.6-0.4-0.21.60.10.9
Progressive ratio test 2 active lever presses0.60.92.10.9-0.90.6-1.4-0.61.01.50.10.7
Progressive ratio test 2 breakpoint0.60.72.30.6-0.70.3-1.4-0.30.81.5-0.10.8
Progressive ratio test 2 inactive lever presses0.62.04.31.8-1.41.1-2.1-1.10.71.90.71.0
Incentive Sensitization - Responses0.51.23.80.7-0.30.1-1.90.1-0.62.0-0.51.6
Incentive Sensitization - Breakpoint0.61.54.60.6-0.30.0-2.00.2-0.72.2-0.71.8
Sum of active levers in priming session hrs 5-60.20.10.30.3-0.30.50.1-0.40.4-0.10.5-0.5
Progressive ratio0.20.61.3-1.21.1-0.60.20.7-0.9-0.1-0.9-0.1
Food seeking constrained by brief footshock1.01.32.70.8-0.50.70.8-1.30.3-1.61.6-1.6
Seeking ratio, punishment vs. effort0.40.91.70.9-0.60.50.8-1.00.4-1.21.3-1.1
Retroperitoneal fat weight0.10.41.30.5-1.10.4-0.2-0.51.00.20.80.5
Reaction time number correct0.10.51.20.7-0.60.3-1.1-0.2-0.11.1-0.01.1
Reaction time mean minus median0.21.01.8-1.30.6-0.9-0.51.10.91.1-1.30.8
Reaction time mean minus median AUC0.10.61.1-0.70.4-0.6-0.70.70.41.0-1.00.9
Reaction time num false alarms1.01.72.6-1.41.1-1.6-0.21.6-1.30.9-1.61.4
Reaction time num false alarms AUC0.61.42.2-1.21.0-1.50.01.4-1.50.6-1.31.2
Reaction time trials correct on left0.10.51.20.7-0.60.3-1.1-0.2-0.11.1-0.01.1
Reaction time trials on left0.20.61.40.8-0.70.3-1.2-0.3-0.01.20.01.1
Reaction time mean0.10.30.9-0.2-0.10.1-0.9-0.00.90.70.20.6
Reaction time mean AUC0.10.20.8-0.30.2-0.0-0.90.20.30.7-0.10.7
Median of all reaction times0.20.30.70.1-0.20.4-0.9-0.30.70.40.60.5
Reaction time omissions1.52.56.12.0-1.81.1-2.5-1.30.81.80.51.5
Reaction time false alarm rate0.91.22.3-1.41.2-1.50.81.3-1.3-0.2-1.10.3
Reaction time premature initiation rate0.10.20.5-0.50.4-0.30.70.50.7-0.4-0.1-0.4
Reaction time premature initiations0.00.10.70.1-0.1-0.00.10.20.80.10.10.1
Std. dev. reaction times0.10.51.8-0.3-0.2-0.2-0.80.21.31.0-0.40.6
Reaction time trials completed0.20.61.40.8-0.70.3-1.2-0.3-0.01.20.01.1
Reaction time trials AUC0.20.71.70.9-0.80.4-1.3-0.3-0.01.30.01.2
Run reversals in cocaine runway, females0.10.10.30.1-0.50.5-0.1-0.40.30.00.2-0.2
Run reversals in cocaine runway, males2.12.44.6-2.12.0-1.61.51.8-0.2-0.5-1.9-0.8
Latency to leave start box in cocaine runway1.11.54.32.1-1.41.4-1.4-1.10.21.00.70.8
Latency to leave start box in cocaine runway, F0.30.40.90.9-0.40.4-0.9-0.10.30.9-0.30.7
Latency to leave start box in cocaine runway, M1.21.22.11.4-1.31.3-1.2-1.1-0.70.70.90.8
Std. dev. time between licks in bursts0.61.12.91.1-1.11.0-1.7-0.80.11.20.51.1
Total sessions with >9 infusions0.40.51.41.2-0.60.8-0.8-0.9-0.40.20.60.0
Short access day 1 total inactive lever presses0.10.10.50.2-0.40.40.1-0.20.7-0.00.3-0.2
Short access day 10 total inactive lever presses0.10.51.61.3-0.80.8-0.4-0.80.30.10.80.1
Short access day 1 total infusions1.02.04.42.1-1.81.7-1.0-1.90.90.31.5-0.3
Short access day 10 total infusions0.10.10.70.2-0.10.60.3-0.30.1-0.30.2-0.8
Short access total infusions0.40.51.10.9-0.81.0-0.3-1.00.60.00.7-0.6
Short access day 1 locomotion0.30.52.70.8-0.20.4-0.2-0.6-1.7-0.20.6-0.1
Short access day 10 total locomotion0.00.20.7-0.20.5-0.5-0.00.3-0.8-0.1-0.30.1
Short access total locomotion0.10.20.9-0.10.5-0.3-0.10.2-0.90.0-0.30.0
One hour access (0.3 mA shock)0.91.03.80.7-1.11.1-0.1-1.12.00.00.7-1.0
Compulsive drug intake0.20.20.5-0.60.1-0.7-0.00.50.20.4-0.50.7
One hour access (shock baseline)0.51.43.11.1-1.31.6-0.7-1.31.80.60.8-0.7
Social response proportion1.72.14.11.7-2.01.0-1.6-1.31.91.01.21.0
Social responses2.02.65.01.8-2.21.2-1.8-1.42.01.41.01.2
Social time1.72.68.4-0.80.0-1.2-1.91.1-0.62.4-1.32.9
Soleus weight0.61.85.2-0.20.70.11.9-0.4-0.9-2.31.0-2.2
Bone: stiffness0.91.62.9-1.21.3-1.61.61.1-1.7-1.2-0.7-0.3
Tibialis anterior weight4.816.430.7-5.55.3-4.84.04.3-3.8-2.4-3.1-1.2
Time to tail flick, vehicle, before self-admin0.70.92.1-1.41.1-1.01.01.10.1-0.5-0.8-0.4
Time to tail flick, vehicle, after self-admin0.40.71.7-1.30.8-0.90.71.01.00.0-0.8-0.2
Time to tail flick, test, before self-admin0.10.10.5-0.2-0.2-0.1-0.40.20.20.6-0.20.7
Time to tail flick, test, after self-admin3.03.15.82.2-2.31.7-2.4-1.70.91.90.91.2
Delta time to tail flick, vehicle, before/after SA0.30.30.70.6-0.80.3-0.7-0.40.60.80.10.5
Delta time to tail flick, test, before/after SA1.41.83.92.0-1.61.4-1.7-1.50.41.11.00.6
Tibia length3.28.915.9-2.92.3-3.1-1.23.5-2.62.7-4.03.6
Ambulatory time before self-admin0.10.31.90.5-0.10.4-0.0-0.2-1.4-0.20.30.2
Ambulatory time after self-admin0.91.54.2-0.31.2-0.51.70.3-2.0-1.80.1-1.1
Bone: tissue strength0.40.41.20.7-0.40.7-1.1-0.2-0.00.9-0.20.7
Total heroin consumption0.30.41.0-1.00.8-0.50.60.60.4-0.0-0.7-0.5
Bone: trabecular number0.91.64.50.9-0.9-0.0-1.9-0.0-0.61.9-0.92.1
Bone: trabecular spacing1.92.77.6-1.11.4-0.32.50.1-0.6-2.60.8-2.8
Bone: trabecular thickness0.50.81.6-1.10.7-1.30.41.2-0.30.2-1.10.7
Bone: trabecular tissue density1.52.64.7-1.52.2-0.92.11.0-1.6-2.0-0.4-1.8
Water consumed over 24 hours0.61.11.9-1.41.2-1.30.31.4-1.00.2-1.40.6
Number of responses in last shaping day0.40.51.5-0.90.6-0.10.90.20.4-0.8-0.2-1.2