Hub : Traits : Tibialis anterior weight : ← →

chr6:96,850,756-98,793,722

Trait: Tibialis anterior weight

Best TWAS P=3.821583e-08 · Best GWAS P=4.439196e-07 conditioned to 0.4206854

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Pigh	gene expression	ENSRNOG00000010914	0.11	0.02	enet	17	0.07	3.4e-08	3.6	5.3	1.0e-07	0.77	0.37	0.63	FALSE
2	Adipose	Rdh11	gene expression	ENSRNOG00000054770	0.22	0.14	enet	67	0.17	3.6e-18	-4.3	5.1	3.0e-07	0.85	0.50	0.49	FALSE
3	BLA	Pigh	alternative polyA	ENSRNOT00000014775	0.12	0.04	enet	30	0.06	5.1e-04	-4.8	-5.2	2.2e-07	-0.69	0.35	0.55	FALSE
4	BLA	Pigh	alternative polyA	ENSRNOT00000101349	0.16	0.05	blup	2175	0.07	8.8e-05	-4.8	5.3	1.3e-07	0.72	0.37	0.60	FALSE
5	BLA	Pigh	gene expression	ENSRNOG00000010914	0.25	0.14	enet	114	0.20	5.3e-11	-4.8	5.5	3.8e-08	0.84	0.25	0.75	TRUE
6	BLA	Pigh	isoform ratio	ENSRNOT00000014775	0.19	0.09	enet	119	0.13	2.8e-07	-4.8	-5.2	2.2e-07	-0.74	0.43	0.56	FALSE
7	BLA	Pigh	isoform ratio	ENSRNOT00000101349	0.18	0.10	enet	156	0.11	1.0e-06	-4.8	5.4	8.0e-08	0.75	0.30	0.69	FALSE
8	BLA	Mpp5	mRNA stability	ENSRNOG00000008788	0.63	0.35	enet	121	0.39	4.3e-22	-4.5	5.1	3.4e-07	0.57	0.14	0.86	FALSE
9	Brain	Atp6v1d	mRNA stability	ENSRNOG00000009080	0.09	0.01	blup	1744	0.04	3.0e-04	-4.9	-5.1	3.1e-07	-0.74	0.15	0.79	FALSE
10	Liver	Pigh	isoform ratio	ENSRNOT00000101349	0.03	0.00	blup	2174	0.00	9.9e-02	-4.5	5.3	1.1e-07	0.73	0.24	0.45	FALSE
11	NAcc	Zfyve26	intron excision ratio	chr6:98082700:98083733	0.33	0.21	enet	95	0.23	3.9e-17	1.5	5.1	2.7e-07	0.61	1.00	0.00	FALSE
12	NAcc	Zfyve26	intron excision ratio	chr6:98082703:98083733	0.34	0.21	enet	96	0.23	2.0e-17	1.5	-5.2	1.8e-07	-0.61	1.00	0.00	FALSE
13	NAcc	Mpp5	mRNA stability	ENSRNOG00000008788	0.46	0.16	enet	23	0.25	1.0e-18	3.6	5.1	2.8e-07	0.75	0.90	0.09	FALSE
14	PL	Pigh	gene expression	ENSRNOG00000010914	0.40	0.25	enet	313	0.27	7.8e-21	4.8	5.2	2.6e-07	0.78	0.27	0.72	FALSE
15	PL	Pigh	isoform ratio	ENSRNOT00000101349	0.13	0.08	blup	2174	0.09	3.6e-07	-4.5	5.4	8.7e-08	0.82	0.21	0.79	FALSE
16	PL	Mpp5	mRNA stability	ENSRNOG00000008788	0.67	0.35	blup	1512	0.45	6.3e-38	-4.4	5.2	1.7e-07	0.74	0.16	0.84	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.