Hub : Genes

Galnt6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Galnt6 0.09 0.07 3.9e-04 0.04 0.03 0.03 0.04 4.5e-05 5.0e-04 1.7e-03 7.9e-05
2 NAcc gene expression Galnt6 0.26 0.08 0.0e+00 0.3 0.41 0.41 0.41 3.1e-35 8.5e-51 2.6e-51 1.4e-51
3 RMTg gene expression Galnt6 0.15 0.1 2.8e-03 -0.01 0.06 -0.01 0 6.8e-01 1.3e-02 4.9e-01 3.1e-01
4 LHb gene expression Galnt6 0.72 0.12 2.5e-11 0.23 0.31 0.41 0.35 2.7e-06 5.2e-08 6.1e-11 3.1e-09
5 NAcc intron excision ratio chr7_131795188_131796363 0.04 0.03 7.6e-03 0.02 0.01 0 0.01 4.1e-03 7.5e-03 6.8e-02 8.2e-03
6 NAcc intron excision ratio chr7_131795188_131796422 0.04 0.03 5.0e-03 0.02 0.02 0.01 0.02 2.9e-03 4.4e-03 4.1e-02 4.8e-03
7 Brain gene expression Galnt6 0.45 0.1 0.0e+00 0.42 0.58 0.58 0.58 1.1e-42 5.6e-66 4.6e-66 5.3e-66
8 pVTA gene expression Galnt6 0.43 0.13 0.0e+00 0.33 0.48 0.47 0.47 4.6e-15 1.9e-23 7.9e-23 1.3e-22
9 BLA gene expression Galnt6 0.4 0.13 0.0e+00 0.38 0.47 0.46 0.46 3.3e-21 9.8e-28 7.3e-27 8.2e-27
10 NAcc intron excision ratio chr7_131819659_131826992 0.03 0.03 8.1e-04 0.01 0.01 0.02 0.01 2.9e-02 1.2e-02 5.3e-03 7.3e-03
11 PL gene expression Galnt6 0.16 0.08 0.0e+00 0.19 0.19 0.2 0.2 1.0e-20 9.3e-21 1.6e-21 1.1e-21
12 LHb isoform ratio XM_006242296.4 0.22 0.13 5.6e-03 0.03 0.09 0.05 0.07 5.7e-02 3.3e-03 2.7e-02 1.0e-02
13 PL mRNA stability Galnt6 0.03 0.02 7.3e-03 0.01 0.02 0.01 0.02 7.6e-03 2.7e-03 9.9e-03 4.3e-03
14 OFC gene expression Galnt6 0.26 0.16 9.7e-04 0.14 0.09 0.21 0.18 2.7e-04 4.0e-03 1.0e-05 5.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density3.35.511.3-3.12.42.2-2.2-3.43.4-2.01.61.6-2.01.62.30.62.8
Area under the delay curve0.40.41.1-1.10.70.8-0.6-0.30.3-0.80.80.6-0.40.40.50.5-0.3
BMI with tail3.110.017.4-4.24.23.9-4.0-2.22.2-3.83.53.4-3.02.91.02.6-0.5
BMI without tail0.61.22.8-1.41.20.9-1.1-1.71.7-0.90.50.8-0.90.70.70.11.4
Body weight2.410.224.9-5.04.03.7-3.7-3.33.3-3.43.22.9-2.62.42.52.00.7
Weight adjusted by age1.01.12.0-0.51.11.1-1.10.6-0.6-1.21.31.2-1.21.4-0.91.4-0.7
Bone surface4.17.315.3-3.82.92.7-2.8-3.93.9-2.52.01.9-2.01.52.90.81.9
Bone volume4.27.112.9-3.62.92.7-2.7-3.53.5-2.52.12.0-2.32.02.41.02.7
Breakpoint value in progressive ratio session0.10.20.6-0.20.1-0.20.2-0.50.50.3-0.4-0.40.4-0.30.8-0.60.2
Number of licking bursts0.91.03.40.7-0.9-0.50.91.8-1.80.6-0.3-0.30.6-0.4-1.00.2-1.8
Context. condit. distance diff. score0.30.41.6-0.80.20.1-0.2-1.31.3-0.1-0.1-0.10.4-0.51.1-0.40.1
Locomotion velocity, session 12.52.75.22.3-1.7-1.91.81.7-1.71.9-1.6-1.71.4-1.4-0.8-1.1-1.1
Locomotion distance, session 11.41.84.62.2-1.4-1.41.31.9-1.91.3-1.1-1.00.8-0.7-1.4-0.5-0.8
Locomotion velocity, session 20.40.50.90.7-0.7-0.90.90.5-0.51.0-0.8-0.90.7-0.80.2-0.70.0
Locomotion distance, session 21.72.45.72.4-1.7-1.71.72.2-2.21.7-1.3-1.20.9-0.6-1.5-0.6-0.3
Locomotion velocity, session 33.84.47.12.4-2.6-2.52.61.2-1.22.7-2.4-2.42.4-2.1-0.2-2.0-0.3
Locomotion distance, session 33.43.75.62.0-2.1-2.32.1-0.50.52.2-2.4-2.22.0-2.10.5-2.32.1
Stereotopy head waving bouts, day 31.41.76.00.10.40.8-0.61.9-1.9-0.81.01.1-0.81.1-1.61.4-2.4
Stereotopy head waving duration, day 30.40.53.20.4-0.6-0.20.51.2-1.20.4-0.1-0.10.20.0-0.60.2-1.8
Locomotion velocity, session 72.73.04.52.1-2.1-2.12.00.1-0.12.0-2.1-1.91.8-2.0-0.0-1.91.4
Locomotion distance, session 74.15.38.32.3-2.8-2.82.70.3-0.32.7-2.8-2.72.7-2.90.3-2.50.5
Stereotopy head waving bouts, day 72.22.44.1-0.81.41.7-1.71.0-1.0-1.81.92.0-1.61.6-1.42.0-1.2
Stereotopy head waving duration, day 72.32.74.4-1.21.61.9-1.90.8-0.8-1.92.02.1-1.51.6-1.12.1-1.8
Locomotion velocity, session 80.20.30.50.7-0.5-0.50.50.6-0.60.5-0.4-0.40.5-0.6-0.5-0.2-0.3
Locomotion distance, session 80.81.21.91.2-1.3-1.41.30.4-0.41.4-1.3-1.31.3-1.20.0-1.1-0.1
Degree of sensitization distance0.40.43.6-0.20.20.3-0.30.7-0.7-0.30.40.30.0-0.0-0.40.5-1.9
Degree of sensitization stereotypy2.42.64.3-1.01.81.9-2.00.6-0.6-2.02.02.1-1.71.6-1.22.1-0.9
Conditioned locomotion0.20.20.70.4-0.5-0.50.5-0.10.10.8-0.5-0.40.6-0.60.3-0.50.4
Cocaine response after cond. corrected0.30.31.30.10.00.2-0.20.9-0.9-0.20.30.30.00.1-0.70.5-1.1
Cocaine response after cond. not corrected0.10.10.40.5-0.4-0.30.20.6-0.60.2-0.2-0.10.3-0.3-0.50.0-0.4
Cocaine response before conditioning1.61.93.11.4-1.5-1.71.6-0.30.31.5-1.7-1.71.6-1.70.4-1.70.5
Saline control response0.40.61.80.1-0.3-0.40.2-1.21.20.3-0.6-0.50.5-0.80.8-0.91.3
Bone: connectivity density1.42.26.9-2.11.31.2-1.3-2.62.6-1.10.80.7-0.80.22.10.00.9
Bone: cortical apparent density0.81.03.91.00.10.2-0.31.6-1.6-0.30.50.7-0.91.1-2.01.0-0.8
Bone: cortical area2.74.18.4-2.92.52.1-2.1-2.72.7-2.01.61.5-1.51.42.00.71.6
Bone: cortical porosity0.70.82.1-0.2-0.3-0.50.4-1.41.40.6-0.7-0.70.5-0.51.3-1.11.4
Bone: cortical porosity0.80.91.60.2-0.6-0.70.6-1.21.20.9-0.9-0.90.7-0.81.1-1.21.2
Bone: cortical thickness0.81.32.7-1.61.51.1-1.1-1.51.5-1.20.80.8-0.90.91.20.40.8
Bone: cortical thickness0.30.40.80.4-0.6-0.70.6-0.40.40.6-0.8-0.70.6-0.90.4-0.80.8
Bone: cortical tissue density0.81.03.91.2-0.00.1-0.11.6-1.6-0.20.40.6-0.81.0-2.00.8-0.8
Condit. Reinf. active minus inactive responses0.10.10.40.20.10.1-0.20.0-0.0-0.20.10.10.2-0.6-0.20.1-0.6
Condit. Reinf. active-inactive response ratio0.30.41.3-0.3-0.0-0.0-0.1-1.01.0-0.0-0.2-0.20.6-1.10.9-0.4-0.2
Condit. Reinf. active responses0.30.31.20.7-0.3-0.30.10.9-0.90.1-0.1-0.10.4-0.5-0.80.1-1.1
Condit. Reinf. inactive responses1.41.76.01.6-0.9-0.90.92.4-2.40.8-0.5-0.40.20.3-1.90.2-1.2
Incentive salience index mean0.30.30.7-0.20.70.6-0.80.1-0.1-0.80.70.6-0.40.2-0.30.7-0.7
Condit. Reinf. lever presses1.21.52.4-0.91.51.4-1.50.5-0.5-1.51.51.4-1.21.2-0.61.5-1.3
Condit. Reinf. active minus inactive responses1.01.22.3-1.31.41.3-1.4-0.40.4-1.51.31.1-1.21.30.21.0-0.2
Condit. Reinf. active-inactive response ratio0.60.61.3-1.11.00.9-0.9-0.50.5-1.10.90.7-0.60.60.40.6-0.2
Condit. Reinf. active responses0.40.61.3-0.51.00.8-0.9-0.20.2-1.10.80.8-1.11.1-0.30.70.5
Condit. Reinf. inactive responses0.20.21.01.0-0.2-0.30.10.5-0.50.0-0.2-0.0-0.30.4-1.00.00.8
Condit. Reinf. lever presses0.40.51.2-0.0-0.4-0.70.8-0.70.70.7-0.8-0.90.4-0.11.0-1.01.1
Condit. Reinf. lever reinforcers received0.10.10.4-0.10.40.2-0.3-0.10.1-0.60.20.2-0.60.6-0.20.20.4
Conditioned reinforcement - actives0.80.82.61.1-0.8-0.70.81.6-1.60.7-0.6-0.40.3-0.3-1.0-0.2-0.7
Conditioned reinforcement - inactives0.91.01.81.3-1.2-1.11.11.3-1.31.0-1.0-0.90.9-0.8-0.6-0.7-0.2
Conditioned locomotion0.50.61.10.4-0.8-0.80.90.5-0.51.0-0.8-0.91.0-0.90.4-0.7-1.1
Patch foraging indifference point 0 sec2.33.610.03.2-2.4-2.42.00.9-0.91.9-2.2-1.91.9-1.9-1.1-1.70.8
Patch foraging indifference point AUC0.40.51.60.40.00.2-0.21.3-1.3-0.30.50.4-0.30.7-1.10.8-0.6
Delay disc. indifference point, 0s delay0.60.72.0-1.41.01.0-0.8-0.60.6-1.00.90.7-0.70.70.80.60.2
Delay disc. indifference point, 16s delay0.30.30.9-0.90.70.6-0.5-0.50.5-0.60.50.5-0.30.20.60.30.0
Delay disc. indifference point, 2s delay3.84.26.6-1.52.22.4-2.30.5-0.5-2.52.52.6-2.42.5-1.22.5-0.7
Delay disc. indifference point, 24s delay0.30.30.7-0.80.60.7-0.50.1-0.1-0.50.60.5-0.20.30.30.5-0.8
Delay disc. indifference point, 4s delay0.40.41.0-1.00.80.9-0.7-0.20.2-0.90.80.7-0.50.50.40.6-0.2
Delay disc. indifference point, 8s delay0.50.51.7-1.20.40.5-0.2-1.21.2-0.40.30.10.1-0.11.3-0.10.2
Indifference point function ln k1.82.65.7-2.42.01.7-1.7-2.22.2-1.51.31.2-1.00.61.80.60.1
Indifference point function log k1.82.65.7-2.42.01.7-1.7-2.22.2-1.51.31.2-1.00.61.80.60.1
Patch foraging total patch changes 0 sec2.54.09.33.0-2.5-2.52.20.6-0.62.0-2.4-2.12.1-2.1-0.8-2.00.8
Patch foraging total patch changes 12 sec2.12.77.22.7-2.1-2.01.61.6-1.61.6-1.6-1.51.4-1.1-1.5-1.10.1
Patch foraging total patch changes 18 sec3.03.89.33.1-2.7-2.42.21.7-1.72.1-2.1-1.91.7-1.4-1.4-1.40.6
Patch foraging total patch changes 24 sec1.72.04.62.2-2.0-1.71.61.1-1.11.5-1.6-1.41.2-1.2-0.9-1.10.3
Patch foraging total patch changes 6 sec2.74.011.03.3-2.5-2.32.11.8-1.81.9-2.0-1.81.9-1.8-1.6-1.3-0.2
Patch foraging time to switch 0 sec0.60.92.81.7-1.1-0.90.71.2-1.20.7-0.7-0.40.3-0.2-1.7-0.20.7
Patch foraging water rate 0 sec1.11.85.8-2.41.41.3-1.2-1.81.8-1.11.00.7-0.40.12.00.3-0.6
Patch foraging water rate 12 sec0.81.23.7-1.81.00.9-0.7-1.81.8-0.60.60.3-0.30.21.9-0.00.2
Patch foraging water rate 18 sec0.10.10.3-0.50.10.3-0.2-0.40.4-0.20.20.10.1-0.30.50.0-0.3
Patch foraging water rate 24 sec1.41.94.6-2.11.71.6-1.5-1.51.5-1.41.41.2-0.90.91.30.8-0.2
Patch foraging water rate 6 sec1.92.88.1-2.91.71.7-1.5-2.42.4-1.41.31.0-0.80.52.40.50.4
Seeking ratio, delayed vs. immediate footshock0.40.50.8-0.90.90.9-0.9-0.40.4-0.90.80.7-0.80.80.30.6-0.2
Distance traveled before self-admin1.01.12.21.5-1.2-1.21.01.2-1.21.1-1.1-1.00.8-0.8-0.9-0.7-0.7
Distance traveled after self-admin1.21.32.20.8-1.2-1.41.2-0.10.11.5-1.4-1.41.5-1.30.5-1.3-0.2
Extensor digitorum longus weight5.722.437.0-4.55.85.9-6.1-0.70.7-6.15.75.9-5.35.1-1.45.3-0.8
Bone: elastic displacement6.87.712.83.2-3.6-3.33.31.4-1.43.4-3.1-3.13.4-3.0-0.3-2.6-1.3
Bone: elastic work1.41.73.50.6-1.4-1.41.5-0.40.41.7-1.5-1.71.9-1.41.3-1.6-0.4
Bone: endosteal estimation2.96.314.0-3.72.72.5-2.4-3.63.6-2.11.81.7-1.41.22.90.62.5
Bone: endosteal perimeter3.16.514.1-3.82.92.8-2.6-3.03.0-2.52.22.2-2.21.92.21.22.1
Epididymis fat weight1.53.57.9-0.5-1.1-1.41.4-2.02.01.6-1.8-2.02.1-2.22.8-2.41.6
Delta time in closed arm before/after self-admin0.10.10.4-0.30.10.0-0.0-0.50.50.0-0.0-0.10.10.10.5-0.20.7
Delta time in open arm before/after self-admin3.83.75.81.8-2.3-2.42.1-0.10.12.4-2.4-2.42.3-2.20.6-2.20.5
Diff in mean of infusions in LGA sessions1.82.03.3-1.41.81.6-1.8-1.11.1-1.61.51.5-1.61.60.11.20.8
Delay discount exponential model param0.40.41.11.0-0.8-0.90.60.2-0.20.9-0.8-0.70.5-0.5-0.4-0.70.4
Extinction: sum of active levers before priming1.31.22.2-1.21.51.3-1.5-0.80.8-1.31.31.2-1.21.30.11.0-0.2
Active lever presses in extinction session 60.00.00.2-0.2-0.1-0.10.1-0.10.10.2-0.2-0.20.2-0.20.5-0.2-0.0
Bone: final force4.26.815.9-4.02.82.4-2.4-4.04.0-2.11.71.5-1.41.23.50.42.0
Bone: final moment4.77.618.9-4.22.92.4-2.4-4.34.3-2.11.71.4-1.31.03.80.32.3
Food consumed during 24 hour testing period1.01.25.2-1.50.60.3-0.4-2.02.0-0.10.0-0.30.4-0.62.3-0.6-0.1
Glucose0.00.00.20.30.1-0.1-0.0-0.10.1-0.1-0.1-0.1-0.40.3-0.2-0.10.5
Heart weight0.30.42.3-0.20.10.0-0.2-1.01.0-0.0-0.2-0.1-0.10.10.7-0.41.5
Delay discount hyperbolic model param0.60.71.21.1-0.9-1.10.80.1-0.11.1-1.1-1.00.7-0.8-0.2-0.90.5
Intermittent access intake day 1-15 change1.11.11.80.5-1.0-1.11.0-0.70.71.1-1.2-1.21.1-1.30.8-1.31.0
Intermittent access intake escalation1.31.32.40.3-1.0-1.11.0-0.90.91.1-1.3-1.31.4-1.41.3-1.51.0
Intermittent access intake escalation 20.90.92.50.3-0.7-0.90.8-0.90.90.8-1.0-1.00.8-0.90.9-1.21.6
Intermitt. access day 1 inactive lever presses0.30.30.60.6-0.6-0.70.60.3-0.30.7-0.7-0.70.4-0.70.1-0.70.2
Intermitt. access day 15 inactive lever presses0.50.61.30.4-0.9-0.90.90.0-0.00.9-0.9-0.91.1-1.00.4-0.9-0.1
Intermitt. access escalation Index0.90.82.80.80.00.1-0.21.5-1.5-0.30.40.5-0.60.8-1.70.9-0.8
Intermittent access day 1 total infusions0.80.91.51.2-1.2-1.11.00.9-0.91.1-1.0-0.91.0-0.9-0.6-0.70.1
Intermittent access day 15 total infusions1.92.13.41.5-1.8-1.81.60.5-0.51.8-1.8-1.61.8-1.70.0-1.60.5
Intermittent access terminal intake (last 3 days)1.41.52.61.4-1.6-1.51.40.6-0.61.4-1.5-1.31.4-1.3-0.3-1.20.6
Intermittent access total infusions1.41.52.51.3-1.6-1.51.40.7-0.71.5-1.5-1.31.5-1.4-0.2-1.20.1
Intermittent access day 1 locomotion1.81.93.01.3-1.7-1.61.60.7-0.71.7-1.6-1.51.7-1.60.1-1.4-0.0
Intermittent access day 15 total locomotion2.22.43.71.0-1.7-1.81.9-0.00.01.8-1.9-1.91.9-1.90.9-1.90.8
Intermittent access total locomotion3.33.85.82.1-2.4-2.32.31.2-1.22.3-2.3-2.12.4-2.2-0.2-1.9-0.1
Intermittent access standard deviation1.41.52.70.2-0.9-1.01.0-1.51.51.0-1.2-1.31.3-1.31.4-1.51.6
Left kidney weight0.71.94.2-1.81.51.2-1.4-2.02.0-1.10.90.9-1.00.91.40.31.8
Right kidney weight1.54.16.7-2.62.62.3-2.4-2.02.0-2.22.01.8-2.11.91.21.31.2
Cocaine induced anxiety0.70.82.8-1.00.30.2-0.4-1.71.7-0.0-0.0-0.1-0.0-0.21.4-0.51.5
Post-drug Anxiety2.42.66.3-2.31.61.6-1.6-2.52.5-1.31.21.1-1.10.81.80.51.5
Baseline Anxiety0.30.40.8-0.80.90.7-0.5-0.20.2-0.80.70.6-0.40.60.40.5-0.5
Tail length0.41.36.7-0.2-0.7-0.70.7-1.41.40.9-1.0-0.80.5-0.81.1-1.32.6
Length with tail0.72.46.8-2.61.41.4-1.1-2.32.3-0.90.90.8-0.80.72.10.21.9
Length without tail1.83.99.7-3.12.42.4-2.2-1.71.7-2.12.11.8-1.61.61.71.50.4
Times rat made contact with spout0.20.20.6-0.2-0.3-0.30.1-0.60.60.2-0.4-0.50.5-0.60.8-0.5-0.0
Lifetime Intake2.32.64.21.6-2.0-1.91.90.8-0.82.0-2.0-1.82.0-1.9-0.0-1.70.1
Liver weight, left0.71.23.5-1.60.80.7-0.6-1.91.9-0.30.30.2-0.30.21.9-0.31.2
Liver weight, right0.81.44.7-1.60.80.5-0.6-2.12.1-0.40.1-0.00.3-0.32.2-0.51.1
Locomotor activity0.40.61.01.0-0.8-0.90.91.0-1.00.7-0.8-0.80.7-0.2-0.5-0.60.0
Locomotor testing distance1.11.93.82.0-1.6-1.81.61.2-1.21.4-1.6-1.51.4-1.0-0.7-1.20.2
Locomotor testing rearing0.81.33.41.5-1.1-1.51.1-0.20.21.0-1.5-1.30.8-0.6-0.2-1.41.9
Locomotion in novel chamber2.12.64.0-2.02.01.9-1.8-1.41.4-1.81.71.8-1.71.50.31.40.8
Locomotion in novel chamber post-restriction0.40.41.8-0.70.1-0.10.2-1.01.00.2-0.3-0.40.6-0.71.4-0.70.1
Fecal boli incidents, locomotor time 12.02.24.30.9-1.5-1.71.70.0-0.01.7-1.8-1.92.1-2.01.0-1.8-0.3
Change in fecal boli incidents, locomotor task0.90.91.5-0.40.71.0-0.90.9-0.9-0.81.11.1-1.11.1-0.91.2-0.7
Time >=10cm from walls, locomotor time 10.50.51.00.6-1.0-0.70.80.5-0.50.8-0.7-0.70.9-1.00.1-0.7-0.3
Bouts of movement, locomotor time 10.30.31.1-0.10.20.2-0.30.9-0.9-0.20.40.2-0.30.4-0.30.5-1.1
Total resting periods, locomotor time 10.50.62.20.6-0.5-0.40.41.5-1.50.3-0.2-0.30.3-0.2-0.60.1-1.4
Rest time, locomotor task time 10.40.41.00.9-0.8-0.60.61.0-1.00.6-0.5-0.50.5-0.5-0.5-0.2-0.3
Distance moved, locomotor task time 10.00.10.20.00.20.2-0.10.0-0.0-0.20.20.2-0.20.4-0.50.3-0.1
Vertical activity count, locomotor time 11.01.01.5-1.01.21.2-1.2-1.11.1-1.11.01.1-1.01.0-0.00.80.4
Time >=10cm from walls, locomotor time 20.40.51.00.7-1.0-0.80.70.2-0.20.7-0.8-0.70.8-1.00.1-0.70.1
Bouts of movement, locomotor time 21.51.63.6-1.91.41.6-1.5-1.41.4-1.51.31.3-0.90.90.80.90.1
Total resting periods, locomotor time 22.12.24.1-2.01.71.9-1.8-1.21.2-1.81.71.7-1.31.30.51.20.1
Rest time, locomotor task time 20.10.10.60.4-0.10.00.10.8-0.80.10.10.10.10.1-0.50.3-0.4
Distance moved, locomotor task time 20.00.00.20.3-0.1-0.20.10.1-0.1-0.0-0.1-0.1-0.10.1-0.40.1-0.1
Vertical activity count, locomotor time 20.10.10.4-0.20.30.2-0.4-0.60.6-0.30.20.2-0.20.20.10.10.2
Light reinforcement 10.50.92.71.1-0.8-0.71.01.7-1.70.7-0.5-0.50.5-0.1-0.9-0.0-1.0
Light reinforcement 20.10.21.0-0.30.40.3-0.10.4-0.4-0.30.40.3-0.71.0-0.20.5-0.1
Bone: marrow area2.86.012.9-3.62.72.4-2.3-3.63.6-2.11.71.6-1.31.22.90.62.5
Bone: maximum diameter1.01.93.3-1.81.71.4-1.4-1.51.5-1.41.11.1-1.31.31.00.61.5
Bone: maximum force5.18.820.4-4.53.53.2-3.1-3.83.8-2.82.52.2-2.11.93.31.21.6
Bone: maximum moment5.69.622.4-4.73.63.2-3.1-4.34.3-2.72.52.2-1.91.83.71.01.9
Mean time between licks in bursts0.50.71.60.7-0.8-0.81.21.1-1.11.2-0.6-0.80.5-0.2-0.0-0.4-1.2
Mean num. licks in bursts1.11.34.7-0.40.3-0.1-0.4-2.22.2-0.1-0.4-0.40.1-0.31.6-1.02.1
Cd content in liver0.50.61.30.7-1.0-0.80.90.3-0.30.8-0.8-0.81.1-1.00.0-0.7-0.6
Co content in liver0.00.10.2-0.1-0.0-0.20.0-0.40.40.1-0.3-0.20.2-0.40.0-0.30.2
Cu content in liver0.60.73.9-0.60.60.4-0.6-1.31.3-0.50.20.3-0.60.50.6-0.12.0
Fe content in liver0.50.51.10.7-0.9-0.91.10.7-0.70.9-0.8-0.70.5-0.5-0.5-0.50.6
K content in liver0.00.00.10.2-0.1-0.20.10.1-0.10.2-0.1-0.3-0.0-0.00.1-0.10.2
Mg content in liver0.20.20.40.5-0.3-0.40.40.6-0.60.4-0.2-0.40.3-0.1-0.1-0.1-0.6
Mn content in liver0.20.30.6-0.30.60.6-0.80.0-0.0-0.60.70.6-0.80.4-0.10.70.0
Na content in liver0.30.33.00.10.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.70.7-0.3-0.01.7
Rb content in liver0.91.22.01.4-1.2-1.41.30.3-0.31.3-1.4-1.31.0-1.2-0.2-1.20.5
Se content in liver0.80.91.61.2-1.2-1.01.01.2-1.21.0-0.8-0.80.8-1.0-0.8-0.4-0.7
Sr content in liver0.80.72.40.0-0.4-0.60.6-1.11.10.7-0.8-0.80.5-0.41.1-1.01.5
Zn content in liver1.71.93.01.6-1.6-1.71.70.9-0.91.7-1.5-1.61.6-1.4-0.2-1.2-0.7
Bone: minimum diameter3.05.513.4-3.72.72.7-2.5-2.82.8-2.32.12.0-1.61.62.31.11.2
Time in familiar zone, hab. session 10.20.10.9-0.20.40.1-0.20.5-0.5-0.10.20.1-0.10.4-0.00.3-1.0
Time in novel zone, hab. session 10.10.10.2-0.10.00.3-0.20.1-0.1-0.30.30.5-0.20.1-0.50.4-0.0
Total zone transitions, hab. session 11.31.93.70.20.90.9-0.91.9-1.9-1.01.31.3-1.31.7-1.91.7-1.3
Total locomotion distance, hab. session 10.30.41.90.9-0.2-0.30.41.4-1.40.3-0.1-0.1-0.10.3-0.90.3-0.6
Locomotion velocity, hab. session 10.20.31.30.7-0.1-0.20.21.1-1.10.20.0-0.1-0.20.5-0.70.3-0.4
Time in familiar zone, hab. session 20.70.71.5-1.20.90.7-0.9-1.21.2-0.70.50.30.1-0.21.20.1-0.9
Time in novel zone, hab. session 20.70.72.11.3-0.8-0.60.81.3-1.30.6-0.5-0.2-0.10.2-1.4-0.00.5
Total zone transitions, hab. session 20.20.20.80.6-0.4-0.40.50.9-0.90.4-0.2-0.30.10.1-0.50.1-0.0
Total locomotion distance, hab. session 20.40.50.90.9-0.8-0.80.90.9-0.90.7-0.6-0.60.5-0.4-0.4-0.4-0.2
Locomotion velocity, hab. session 20.30.40.70.6-0.7-0.70.90.7-0.70.7-0.6-0.70.4-0.2-0.1-0.50.3
Novel to familiar place preference ratio2.12.23.5-1.41.71.8-1.80.0-0.0-1.71.81.9-1.91.7-0.51.70.1
Novelty place preference1.71.72.9-1.11.51.6-1.50.2-0.2-1.51.61.6-1.71.5-0.61.6-0.0
Time in novel zone, NPP test1.61.62.7-0.91.41.5-1.40.3-0.3-1.41.61.6-1.71.5-0.81.6-0.1
Total zone transitions, NPP test1.21.85.01.9-1.4-1.31.32.2-2.21.2-0.8-0.90.4-0.1-1.6-0.2-0.4
Total locomotion distance, NPP test2.33.15.82.4-2.1-2.02.12.3-2.31.9-1.6-1.71.3-1.0-1.2-0.9-0.7
Locomotion velocity, NPP test1.72.43.82.0-1.9-1.82.01.8-1.81.7-1.5-1.61.2-1.0-0.7-0.9-0.6
Intraocular pressure2.83.97.42.7-2.3-2.52.30.7-0.72.3-2.4-2.22.2-2.2-0.5-2.0-0.6
Delta distance traveled before/after self-admin1.61.73.9-0.5-0.6-0.80.7-1.91.91.0-1.1-1.21.3-1.32.0-1.51.3
Delta ambulatory time before/after self-admin1.61.83.6-0.1-0.8-1.00.9-1.71.71.1-1.2-1.31.4-1.41.9-1.61.5
Parametrial fat weight2.03.86.91.1-2.1-2.22.30.1-0.12.3-2.3-2.42.6-2.61.1-2.2-1.3
Pavlov. Cond. lever latency1.01.22.10.8-1.2-1.31.4-0.20.21.4-1.4-1.31.3-1.20.6-1.40.2
Pavlov. Cond. magazine entry latency1.62.03.7-1.21.61.8-1.8-0.10.1-1.91.81.8-1.51.5-0.51.7-0.1
Pavlov. Cond. change in total contacts2.52.74.9-1.51.92.0-2.1-0.10.1-2.22.02.0-1.91.6-0.51.9-0.5
Pavlov. Cond. index score2.32.95.4-1.32.02.0-2.2-0.10.1-2.32.02.1-2.01.9-0.82.00.1
Pavlov. Cond. latency score2.12.64.9-1.31.91.9-2.1-0.10.1-2.21.92.0-1.91.8-0.71.80.2
Pavlov. Cond. lever contacts0.70.81.6-0.71.11.1-1.2-0.00.0-1.21.11.1-1.11.0-0.41.00.4
Pavlov. Cond. magazine entry number0.60.81.80.8-1.0-1.11.20.4-0.41.4-1.1-1.10.8-0.60.1-0.9-0.0
Pavlov. Cond. intertrial magazine entries2.83.46.52.6-2.2-2.32.21.4-1.42.3-2.1-2.01.8-1.5-0.8-1.5-0.5
Pavlov. Cond. lever-magazine prob. diff.2.32.95.3-1.52.02.1-2.2-0.10.1-2.32.12.1-2.01.8-0.62.0-0.0
Pavlov. Cond. response bias0.60.71.5-0.81.01.1-1.1-0.10.1-1.21.11.1-0.90.7-0.31.00.0
Pavlov. Cond. lever latency0.91.22.7-0.81.31.5-1.6-0.40.4-1.41.41.5-1.00.5-0.31.2-0.2
Pavlov. Cond. magazine entry latency1.21.32.40.2-1.4-1.21.50.3-0.31.4-1.2-1.41.4-1.40.8-1.2-1.1
Pavlov. Cond. change in total contacts1.11.64.6-1.31.51.3-1.20.2-0.2-1.51.41.3-1.62.1-0.41.4-0.5
Pavlov. Cond. index score0.70.92.20.4-1.1-1.21.50.5-0.51.2-1.1-1.30.8-0.40.4-1.0-0.4
Pavlov. Cond. latency score0.60.71.90.3-1.0-1.11.40.5-0.51.1-1.0-1.20.7-0.40.3-0.9-0.4
Pavlov. Cond. lever contacts1.11.43.20.8-1.4-1.61.80.3-0.31.6-1.5-1.61.2-0.70.5-1.40.3
Pavlov. Cond. magazine entry number0.20.30.70.10.50.6-0.8-0.20.2-0.70.60.8-0.40.3-0.60.60.7
Pavlov. Cond. intertrial magazine entries1.82.33.91.5-1.4-1.61.1-1.11.11.5-1.8-1.61.5-1.80.7-1.92.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.10.1-0.7-0.81.00.4-0.40.8-0.7-0.90.40.00.3-0.6-0.4
Pavlov. Cond. response bias1.01.43.20.5-1.3-1.51.80.2-0.21.6-1.5-1.71.2-0.80.8-1.4-0.3
Time in closed arm before self-admin1.01.22.1-0.91.21.4-1.5-0.20.2-1.41.41.4-1.21.0-0.41.3-0.2
Time in closed arm after self-admin1.01.01.7-0.61.11.2-1.10.4-0.4-1.21.31.3-1.11.2-0.71.3-0.2
Time in open arm before self-admin1.61.72.7-0.31.01.1-0.91.5-1.5-1.21.41.4-1.41.6-1.41.6-1.5
Time in open arm after self-admin0.20.20.50.5-0.4-0.40.40.6-0.60.3-0.3-0.30.2-0.1-0.4-0.1-0.7
Bone: periosteal estimation4.08.418.1-4.33.32.9-2.8-4.04.0-2.62.12.0-1.91.73.20.92.8
Bone: periosteal perimeter4.47.315.3-3.93.33.1-3.0-2.92.9-2.92.62.5-2.42.12.01.61.6
Bone: post-yield work3.24.39.1-3.02.42.1-2.0-2.92.9-1.81.61.4-1.41.22.30.71.9
Progressive ratio test 1 active lever presses5.76.09.43.0-3.1-3.02.91.6-1.62.9-2.9-2.62.8-2.4-0.7-2.30.2
Progressive ratio test 1 breakpoint4.64.87.62.7-2.8-2.62.51.6-1.62.6-2.5-2.32.4-2.1-0.8-2.00.2
Progressive ratio test 1 inactive lever presses1.51.62.31.5-1.5-1.51.41.4-1.41.4-1.4-1.21.3-1.2-0.5-1.1-0.2
Progressive ratio test 2 active lever presses1.71.82.71.3-1.7-1.61.70.8-0.81.6-1.6-1.51.6-1.4-0.0-1.40.4
Progressive ratio test 2 breakpoint1.51.72.61.3-1.6-1.51.60.8-0.81.6-1.6-1.41.5-1.3-0.1-1.40.5
Progressive ratio test 2 inactive lever presses1.61.83.11.2-1.6-1.61.50.6-0.61.6-1.7-1.51.8-1.60.3-1.60.2
Incentive Sensitization - Responses0.40.40.7-0.80.70.7-0.6-0.20.2-0.70.60.7-0.70.70.20.40.8
Incentive Sensitization - Breakpoint0.40.40.8-0.80.70.7-0.6-0.10.1-0.70.60.7-0.80.80.00.50.9
Sum of active levers in priming session hrs 5-60.40.41.00.8-0.7-0.60.71.0-1.00.6-0.5-0.50.4-0.2-0.5-0.2-0.5
Progressive ratio0.70.91.31.1-1.2-1.01.11.1-1.11.1-0.8-0.90.7-0.7-0.5-0.5-0.8
Food seeking constrained by brief footshock1.11.42.91.7-1.7-1.51.40.8-0.81.4-1.3-1.21.0-1.1-0.6-0.90.2
Seeking ratio, punishment vs. effort0.10.10.4-0.30.20.2-0.3-0.50.5-0.30.10.1-0.10.00.3-0.00.6
Retroperitoneal fat weight1.44.68.71.5-2.4-2.62.60.2-0.22.7-2.5-2.72.9-2.61.1-2.4-0.1
Reaction time number correct1.21.76.2-0.90.60.3-0.5-2.52.5-0.2-0.1-0.0-0.1-0.41.8-0.72.5
Reaction time mean minus median1.72.25.82.4-1.9-1.81.61.3-1.31.5-1.6-1.40.7-0.7-1.3-1.11.4
Reaction time mean minus median AUC1.01.34.22.1-1.2-1.31.01.3-1.31.0-1.0-0.80.0-0.1-1.5-0.50.8
Reaction time num false alarms1.11.53.81.6-1.1-0.91.01.9-1.90.8-0.6-0.60.9-0.8-1.2-0.1-2.0
Reaction time num false alarms AUC1.31.85.91.7-0.9-0.80.82.3-2.30.5-0.4-0.40.7-0.6-1.60.2-2.4
Reaction time trials correct on left1.21.76.2-0.90.60.3-0.5-2.52.5-0.2-0.1-0.0-0.1-0.41.8-0.72.5
Reaction time trials on left1.11.66.3-0.80.50.2-0.4-2.42.4-0.1-0.2-0.1-0.1-0.51.7-0.82.5
Reaction time mean0.30.51.10.7-0.8-0.80.8-0.10.10.9-0.9-0.70.4-0.6-0.2-0.71.0
Reaction time mean AUC0.20.31.00.5-0.6-0.60.6-0.30.30.7-0.7-0.50.2-0.5-0.1-0.61.0
Median of all reaction times0.10.20.5-0.1-0.2-0.30.3-0.60.60.4-0.4-0.30.2-0.40.3-0.50.7
Reaction time omissions3.34.510.53.2-2.6-2.72.61.5-1.52.4-2.5-2.21.5-1.6-1.3-1.81.0
Reaction time false alarm rate2.12.910.31.6-0.7-0.50.63.2-3.20.20.10.00.30.1-2.30.9-3.2
Reaction time premature initiation rate2.73.66.42.4-2.5-2.42.10.8-0.82.2-2.2-2.22.1-2.2-0.4-1.8-0.4
Reaction time premature initiations2.23.15.61.8-2.1-2.11.7-0.70.71.9-2.2-2.11.9-2.40.6-2.11.0
Std. dev. reaction times1.42.05.42.3-1.7-1.71.51.5-1.51.5-1.4-1.20.6-0.6-1.5-0.90.8
Reaction time trials completed1.11.66.3-0.80.50.2-0.4-2.42.4-0.1-0.2-0.1-0.1-0.51.7-0.82.5
Reaction time trials AUC1.31.86.5-1.10.90.6-0.7-2.52.5-0.50.10.2-0.4-0.21.7-0.52.5
Run reversals in cocaine runway, females0.40.41.4-0.4-0.0-0.0-0.1-1.21.20.2-0.3-0.20.4-0.50.9-0.61.0
Run reversals in cocaine runway, males0.90.83.50.90.20.3-0.51.2-1.2-0.60.50.8-1.01.1-1.90.90.1
Latency to leave start box in cocaine runway0.91.03.20.10.40.6-0.41.5-1.5-0.70.80.7-0.80.8-1.11.2-1.8
Latency to leave start box in cocaine runway, F2.02.28.71.4-0.5-0.30.43.0-3.00.10.10.2-0.20.4-2.10.8-2.3
Latency to leave start box in cocaine runway, M1.41.32.7-1.61.31.2-1.2-1.51.5-1.21.10.9-1.10.80.80.80.2
Std. dev. time between licks in bursts0.91.12.11.2-1.4-1.31.51.0-1.01.4-1.1-1.10.9-0.6-0.4-0.80.1
Total sessions with >9 infusions1.31.42.31.2-1.4-1.41.50.8-0.81.5-1.4-1.31.4-1.1-0.2-1.2-0.2
Short access day 1 total inactive lever presses0.91.01.41.1-1.1-1.21.20.9-0.91.2-1.1-1.11.0-1.0-0.2-0.9-0.5
Short access day 10 total inactive lever presses0.30.30.9-0.2-0.1-0.20.1-0.90.90.2-0.4-0.40.1-0.50.8-0.60.9
Short access day 1 total infusions0.60.71.20.7-0.9-1.01.10.3-0.31.0-1.0-0.90.9-0.90.1-0.90.7
Short access day 10 total infusions2.12.33.71.9-1.9-1.81.71.2-1.21.8-1.7-1.61.7-1.5-0.6-1.30.1
Short access total infusions1.92.23.41.4-1.8-1.81.80.6-0.61.8-1.8-1.71.8-1.70.1-1.60.3
Short access day 1 locomotion0.20.20.90.2-0.4-0.40.51.0-1.00.4-0.3-0.30.3-0.2-0.2-0.2-0.3
Short access day 10 total locomotion0.20.20.30.4-0.4-0.50.50.4-0.40.4-0.5-0.40.4-0.4-0.0-0.50.5
Short access total locomotion0.40.40.60.8-0.8-0.80.80.8-0.80.7-0.8-0.60.5-0.6-0.3-0.60.3
One hour access (0.3 mA shock)0.00.10.2-0.40.20.3-0.1-0.40.4-0.20.20.3-0.1-0.10.10.1-0.0
Compulsive drug intake1.41.52.6-1.61.61.5-1.2-0.50.5-1.41.51.4-1.21.00.21.2-0.9
One hour access (shock baseline)0.10.10.9-0.0-0.2-0.1-0.1-0.40.40.1-0.2-0.10.1-0.10.2-0.31.0
Social response proportion0.90.91.5-0.2-0.7-0.80.8-1.21.20.7-1.0-1.01.0-1.01.2-1.20.9
Social responses1.31.63.51.9-1.7-1.41.31.5-1.51.0-1.2-1.00.9-0.8-1.4-0.6-0.6
Social time0.60.82.3-0.6-0.1-0.30.4-1.51.50.4-0.5-0.60.7-0.71.5-0.91.0
Soleus weight0.51.42.9-1.71.41.1-1.1-1.51.5-1.10.90.8-1.11.21.30.41.0
Bone: stiffness7.511.826.5-5.14.23.9-3.7-3.73.7-3.53.33.0-3.02.63.02.01.8
Tibialis anterior weight6.421.734.4-3.85.55.6-5.80.4-0.4-5.85.75.9-5.25.2-2.45.5-2.2
Time to tail flick, vehicle, before self-admin0.20.20.70.8-0.3-0.20.20.7-0.70.0-0.1-0.0-0.0-0.0-0.80.2-0.3
Time to tail flick, vehicle, after self-admin0.50.61.1-0.80.91.0-1.0-0.20.2-0.90.90.9-0.90.7-0.00.8-0.3
Time to tail flick, test, before self-admin0.30.31.40.60.20.2-0.30.6-0.6-0.30.40.5-0.70.7-1.20.70.3
Time to tail flick, test, after self-admin0.60.62.0-0.70.60.5-0.6-1.41.4-0.40.40.4-0.40.20.80.01.4
Delta time to tail flick, vehicle, before/after SA0.30.31.0-1.00.50.4-0.5-1.01.0-0.20.20.2-0.0-0.01.0-0.20.5
Delta time to tail flick, test, before/after SA0.40.41.2-1.00.40.4-0.3-1.11.1-0.30.20.1-0.0-0.11.0-0.10.5
Tibia length1.85.014.2-3.71.91.7-1.6-3.83.8-1.21.00.8-0.60.53.6-0.31.7
Ambulatory time before self-admin2.02.13.92.0-1.7-1.71.51.5-1.51.6-1.5-1.41.2-1.2-0.9-1.0-1.0
Ambulatory time after self-admin2.52.74.41.4-1.8-2.01.9-0.10.12.1-2.0-2.12.0-1.90.7-2.00.3
Bone: tissue strength1.00.92.1-1.21.51.1-1.2-0.50.5-1.11.11.0-0.81.00.40.8-0.7
Total heroin consumption0.60.83.3-1.20.70.2-0.2-1.51.5-0.0-0.1-0.2-0.1-0.21.8-0.60.4
Bone: trabecular number1.82.78.8-2.11.31.1-1.1-3.03.0-1.00.60.5-0.90.42.3-0.22.1
Bone: trabecular spacing0.40.62.10.8-0.2-0.20.31.5-1.50.2-0.00.10.10.1-1.40.4-0.8
Bone: trabecular thickness0.70.82.0-0.61.01.0-1.1-0.20.2-1.11.01.0-1.41.2-0.20.90.5
Bone: trabecular tissue density2.43.45.8-0.91.51.8-1.51.9-1.9-1.72.12.0-2.02.4-1.52.4-1.6
Water consumed over 24 hours1.51.84.20.3-1.3-1.21.0-1.21.21.2-1.4-1.41.7-2.11.5-1.70.8
Number of responses in last shaping day0.10.10.1-0.40.30.4-0.3-0.30.3-0.30.30.3-0.30.00.10.3-0.3