Hub : Genes

Galnt6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Galnt6 0.11 0.08 1.8e-04 0.03 0.03 0.02 0.02 8.4e-04 1.1e-03 4.0e-03 2.9e-03
2 IC gene expression Galnt6 0.23 0.11 8.5e-10 0.15 0.22 0.22 0.23 5.6e-07 1.4e-09 9.9e-10 7.2e-10
3 NAcc gene expression Galnt6 0.34 0.12 0.0e+00 0.29 0.45 0.46 0.46 5.1e-45 6.3e-76 1.3e-78 2.1e-78
4 OFC gene expression Galnt6 0.3 0.17 2.8e-04 0.05 0.12 0.09 0.11 3.1e-02 1.0e-03 3.7e-03 1.3e-03
5 NAcc mRNA stability Galnt6 0.03 0.03 6.2e-03 0.01 0.01 0.01 0.01 3.8e-03 2.0e-02 2.0e-02 1.5e-02
6 Brain gene expression Galnt6 0.44 0.1 0.0e+00 0.41 0.53 0.53 0.53 1.7e-41 7.9e-58 2.0e-58 2.6e-58
7 RMTg gene expression Galnt6 0.16 0.12 3.0e-03 0 0.04 0.04 0.02 2.4e-01 3.1e-02 2.9e-02 1.2e-01
8 pVTA gene expression Galnt6 0.38 0.12 0.0e+00 0.29 0.46 0.46 0.46 2.2e-23 4.7e-41 7.3e-41 1.1e-40
9 LHb isoform ratio XM_006242296.5 0.32 0.16 5.0e-04 0.14 0.15 0.17 0.13 3.9e-04 2.0e-04 9.2e-05 5.7e-04
10 NAcc intron excision ratio chr7_133698437_133705770 0.03 0.02 2.0e-04 0.01 0.02 0.01 0.01 4.0e-02 1.3e-03 1.7e-02 1.4e-02
11 PL gene expression Galnt6 0.18 0.09 0.0e+00 0.18 0.2 0.2 0.2 1.0e-19 2.9e-21 2.4e-21 4.3e-21
12 BLA gene expression Galnt6 0.43 0.16 0.0e+00 0.41 0.43 0.44 0.44 5.4e-23 6.8e-25 4.3e-25 3.4e-25
13 PL mRNA stability Galnt6 0.02 0.02 6.3e-03 0.02 0.02 0.01 0.02 6.6e-03 2.6e-03 2.0e-02 6.8e-03
14 RMTg alternative TSS XM_063262835.1 0.23 0.16 1.1e-03 0.15 0.06 0.05 0.09 1.1e-04 1.4e-02 1.6e-02 2.6e-03
15 RMTg isoform ratio XM_063262835.1 0.15 0.12 8.4e-03 0.15 0.02 0.08 0.11 9.6e-05 8.0e-02 4.1e-03 7.6e-04
16 NAcc alternative TSS XM_063262835.1 0.08 0.06 2.6e-05 0.02 0.03 0.02 0.01 1.3e-03 3.9e-05 1.1e-04 2.3e-03
17 LHb gene expression Galnt6 0.65 0.14 2.2e-10 0.14 0.3 0.36 0.35 3.5e-04 8.7e-08 2.0e-09 3.6e-09
18 NAcc alternative TSS XM_006242296.5 0.11 0.09 6.1e-04 0.02 0.03 0.02 0.02 3.0e-04 7.7e-05 3.3e-04 8.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density2.13.611.23.02.32.12.03.32.32.11.72.81.61.61.10.9-0.3-0.3-0.71.60.2
Area under the delay curve0.50.61.41.20.91.00.90.60.80.80.80.70.70.60.80.60.90.9-0.2-0.10.1
BMI with tail2.910.023.34.84.04.14.23.34.13.53.52.73.43.42.92.72.12.10.00.8-0.4
BMI without tail0.92.76.62.61.92.12.02.62.31.71.71.31.71.51.71.10.10.10.21.3-0.8
Body weight2.511.133.75.83.94.14.24.93.93.73.44.23.12.92.82.11.41.4-1.30.40.4
Weight adjusted by age1.62.45.20.61.71.71.6-0.61.71.71.8-0.81.82.01.72.00.60.61.72.3-1.5
Bone surface2.75.013.83.72.72.52.63.72.62.52.13.41.91.81.41.10.40.4-1.11.10.5
Bone volume2.74.812.83.62.72.52.53.52.72.62.23.02.01.91.61.30.30.3-0.71.40.1
Breakpoint value in progressive ratio session0.20.21.10.90.60.30.50.90.20.40.31.00.20.20.00.0-0.1-0.1-0.5-0.40.4
Number of licking bursts0.30.52.9-0.6-0.7-0.6-0.5-1.7-0.8-0.4-0.3-1.1-0.3-0.5-0.10.10.70.70.3-1.1-0.3
Context. condit. distance diff. score0.20.21.30.80.30.40.31.10.40.10.10.90.00.1-0.1-0.2-0.3-0.3-0.70.20.5
Locomotion velocity, session 11.92.15.0-2.2-1.7-1.8-1.7-1.5-1.9-1.9-1.6-1.2-1.5-1.2-1.4-1.2-0.8-0.8-0.1-0.80.7
Locomotion distance, session 11.21.54.8-2.2-1.4-1.5-1.4-2.0-1.5-1.3-1.2-1.6-1.1-0.9-1.0-0.7-0.2-0.20.6-0.80.1
Locomotion velocity, session 20.50.60.9-0.8-0.8-0.9-0.8-0.3-0.9-0.8-0.8-0.1-0.9-0.7-0.9-0.7-0.6-0.6-0.6-0.80.8
Locomotion distance, session 21.72.45.8-2.4-1.8-2.1-1.8-2.2-2.0-1.7-1.6-1.6-1.5-1.4-1.4-1.0-0.5-0.50.3-1.30.4
Locomotion velocity, session 33.64.16.7-2.3-2.6-2.5-2.5-1.1-2.6-2.4-2.4-0.9-2.3-2.4-2.2-2.0-1.8-1.8-0.9-0.91.1
Locomotion distance, session 33.84.18.7-1.9-2.2-2.1-2.40.6-2.1-2.1-2.30.1-2.2-2.3-2.3-2.3-3.0-3.0-1.10.50.9
Stereotopy head waving bouts, day 31.21.43.9-0.00.60.60.8-1.90.60.80.9-1.41.00.81.21.32.02.01.4-0.6-1.1
Stereotopy head waving duration, day 30.30.31.7-0.3-0.4-0.4-0.1-1.3-0.3-0.1-0.1-0.7-0.1-0.30.10.21.01.00.2-1.10.0
Locomotion velocity, session 72.93.25.4-2.0-2.1-2.2-2.2-0.0-1.9-2.0-2.1-0.5-2.0-2.1-2.0-2.0-2.3-2.3-0.60.20.4
Locomotion distance, session 73.95.07.1-2.3-2.7-2.7-2.7-0.4-2.6-2.7-2.6-0.3-2.6-2.7-2.5-2.5-2.3-2.3-1.3-0.91.4
Stereotopy head waving bouts, day 73.53.95.91.02.02.02.0-0.82.12.02.2-1.22.32.32.32.41.91.92.21.4-2.4
Stereotopy head waving duration, day 72.32.74.11.21.71.71.8-0.61.81.81.9-0.72.01.91.92.01.81.81.60.8-1.7
Locomotion velocity, session 80.10.20.5-0.7-0.5-0.5-0.4-0.6-0.4-0.6-0.4-0.7-0.3-0.3-0.3-0.2-0.2-0.20.30.2-0.2
Locomotion distance, session 80.81.22.0-1.3-1.2-1.4-1.2-0.5-1.3-1.4-1.3-0.3-1.3-1.1-1.4-1.2-0.9-0.9-0.7-0.71.1
Degree of sensitization distance0.40.41.60.10.30.20.5-1.00.30.20.4-0.40.40.50.40.51.31.30.4-1.00.0
Degree of sensitization stereotypy3.03.35.11.01.92.01.8-0.42.01.82.1-0.92.12.32.02.11.51.51.91.7-2.1
Conditioned locomotion0.40.50.9-0.5-0.7-0.8-0.7-0.0-1.0-0.6-0.70.2-0.7-0.8-0.9-0.7-0.8-0.8-0.4-0.50.5
Cocaine response after cond. corrected0.10.10.7-0.20.10.00.2-0.80.00.20.2-0.70.20.10.40.40.30.30.50.0-0.3
Cocaine response after cond. not corrected0.10.10.5-0.6-0.3-0.4-0.4-0.5-0.4-0.3-0.3-0.7-0.2-0.3-0.1-0.1-0.3-0.30.30.1-0.2
Cocaine response before conditioning1.51.82.8-1.4-1.6-1.5-1.60.2-1.5-1.7-1.6-0.0-1.6-1.5-1.6-1.6-1.3-1.3-0.7-0.60.8
Saline control response0.30.41.4-0.1-0.6-0.5-0.61.2-0.4-0.5-0.60.6-0.6-0.8-0.6-0.8-1.0-1.0-0.50.50.1
Bone: connectivity density0.91.46.01.91.31.11.12.51.21.10.82.30.70.80.30.2-0.4-0.4-1.00.90.7
Bone: cortical apparent density0.91.24.1-1.00.30.30.3-2.00.40.40.5-2.00.70.70.91.01.31.32.00.2-1.4
Bone: cortical area2.43.610.53.22.32.22.32.92.22.11.92.51.81.61.51.20.50.5-0.71.20.0
Bone: cortical porosity0.60.71.80.1-0.3-0.5-0.51.3-0.5-0.3-0.61.3-0.6-0.6-0.9-0.9-1.3-1.3-1.10.30.9
Bone: cortical porosity0.90.92.4-0.2-0.6-0.8-0.81.2-0.8-0.6-0.81.2-0.9-0.8-1.1-1.1-1.5-1.5-1.10.41.0
Bone: cortical thickness0.91.44.32.11.41.31.51.71.41.21.31.31.21.11.00.90.70.7-0.30.6-0.1
Bone: cortical thickness0.50.61.5-0.3-0.8-0.7-0.80.8-0.7-0.8-0.80.2-0.8-0.8-0.7-0.9-1.2-1.2-0.50.40.3
Bone: cortical tissue density0.81.24.3-1.10.20.20.2-2.10.30.30.4-2.00.60.50.80.91.21.21.90.1-1.4
Condit. Reinf. active minus inactive responses0.00.00.1-0.10.20.20.2-0.10.2-0.10.1-0.20.20.20.10.20.10.10.30.4-0.1
Condit. Reinf. active-inactive response ratio0.10.20.80.30.20.20.10.90.20.00.00.8-0.0-0.1-0.2-0.2-0.5-0.5-0.50.40.4
Condit. Reinf. active responses0.10.20.8-0.7-0.2-0.3-0.2-0.9-0.2-0.6-0.2-0.9-0.10.1-0.10.10.30.30.5-0.1-0.1
Condit. Reinf. inactive responses0.91.14.8-1.7-1.0-1.1-0.9-2.2-1.1-1.1-0.7-1.9-0.6-0.4-0.4-0.10.50.50.9-0.8-0.3
Incentive salience index mean0.30.40.90.30.80.80.8-0.00.70.40.7-0.20.80.90.60.80.50.50.60.6-0.4
Condit. Reinf. lever presses1.11.62.90.91.51.41.5-0.21.31.21.5-0.21.51.71.31.51.51.50.90.4-0.7
Condit. Reinf. active minus inactive responses0.70.91.81.21.11.11.20.41.31.11.10.41.01.11.11.00.70.70.30.1-0.3
Condit. Reinf. active-inactive response ratio0.30.41.11.00.70.80.90.60.90.70.70.50.60.50.80.50.50.5-0.1-0.20.0
Condit. Reinf. active responses0.30.40.90.30.60.60.70.11.00.60.6-0.10.70.70.70.60.30.30.60.7-0.7
Condit. Reinf. inactive responses0.20.31.0-1.0-0.3-0.3-0.3-0.7-0.0-0.4-0.2-0.8-0.10.1-0.10.0-0.3-0.30.90.8-0.8
Condit. Reinf. lever presses0.60.81.80.1-0.8-0.8-0.60.8-0.8-0.7-0.81.1-0.9-1.0-0.9-1.0-0.7-0.7-1.3-1.01.2
Condit. Reinf. lever reinforcers received0.00.00.20.10.10.10.20.10.40.10.10.00.20.20.20.1-0.1-0.10.20.3-0.2
Conditioned reinforcement - actives0.50.92.5-1.0-1.0-1.1-1.2-0.3-1.2-1.1-1.0-0.4-1.0-1.1-1.2-0.9-0.1-0.1-0.3-1.60.2
Conditioned reinforcement - inactives2.23.25.4-2.3-2.1-2.1-2.2-1.3-2.2-2.2-2.0-1.2-1.9-2.0-1.9-1.7-1.9-1.9-0.2-0.20.2
Conditioned locomotion0.91.27.3-0.5-1.0-1.1-0.9-0.0-1.2-1.0-1.00.2-1.0-1.1-1.2-1.00.60.6-0.9-2.70.8
Patch foraging indifference point 0 sec2.03.79.2-3.0-2.5-2.0-2.6-1.0-1.9-2.5-2.3-1.8-2.1-2.1-1.9-2.0-1.4-1.40.3-0.0-0.4
Patch foraging indifference point AUC0.30.41.9-0.9-0.2-0.2-0.3-1.4-0.4-0.4-0.0-1.30.00.3-0.70.40.60.60.90.2-0.5
Delay disc. indifference point, 0s delay0.70.82.21.51.11.01.11.00.91.01.01.20.80.70.60.70.30.3-0.50.90.3
Delay disc. indifference point, 16s delay0.30.31.11.00.50.60.50.80.50.50.40.80.40.20.60.20.40.4-0.4-0.40.2
Delay disc. indifference point, 2s delay4.04.46.51.42.22.52.3-0.32.42.42.5-0.62.52.42.52.51.91.92.01.9-2.0
Delay disc. indifference point, 24s delay0.20.30.60.80.50.60.70.20.40.50.50.50.50.40.50.50.70.7-0.2-0.50.4
Delay disc. indifference point, 4s delay0.60.71.51.21.01.11.00.80.90.90.90.70.80.70.60.70.60.6-0.10.6-0.0
Delay disc. indifference point, 8s delay0.40.41.81.20.40.40.41.10.30.30.21.30.1-0.10.1-0.10.30.3-1.1-0.70.8
Indifference point function ln k1.32.25.12.31.81.61.82.21.81.91.42.11.31.11.70.80.50.5-0.60.10.2
Indifference point function log k1.32.25.12.31.81.61.82.21.81.91.42.11.31.11.70.80.50.5-0.60.10.2
Patch foraging total patch changes 0 sec2.14.08.5-2.9-2.6-2.1-2.7-0.7-2.1-2.6-2.5-1.4-2.2-2.3-2.1-2.2-1.6-1.6-0.1-0.2-0.1
Patch foraging total patch changes 12 sec2.12.87.6-2.8-2.1-1.7-2.1-1.7-1.8-2.2-1.8-2.0-1.6-1.3-2.0-1.30.10.10.6-1.1-0.2
Patch foraging total patch changes 18 sec2.13.38.5-2.9-2.3-2.1-2.4-1.6-2.0-2.4-2.0-2.0-1.8-1.6-2.2-1.5-1.0-1.00.5-0.0-0.3
Patch foraging total patch changes 24 sec1.11.94.7-2.2-1.7-1.3-1.8-0.8-1.5-1.9-1.5-1.4-1.4-1.2-1.9-1.2-0.9-0.90.3-0.0-0.2
Patch foraging total patch changes 6 sec2.33.59.9-3.1-2.4-1.9-2.4-2.0-2.1-2.4-2.0-2.2-1.8-1.7-2.0-1.5-0.9-0.90.6-0.3-0.2
Patch foraging time to switch 0 sec0.51.14.5-1.8-1.1-0.8-1.2-1.4-0.7-0.9-0.8-2.1-0.5-0.5-0.1-0.4-0.4-0.41.30.8-1.4
Patch foraging water rate 0 sec0.92.06.82.61.51.41.72.11.21.21.32.51.01.00.20.70.60.6-1.3-0.51.2
Patch foraging water rate 12 sec0.61.24.81.81.21.11.11.80.80.90.82.20.60.7-0.30.3-0.0-0.0-1.2-0.41.2
Patch foraging water rate 18 sec0.10.10.60.50.40.30.40.20.20.40.20.80.10.20.20.1-0.0-0.0-0.4-0.50.6
Patch foraging water rate 24 sec1.31.84.72.21.81.61.81.41.41.51.51.91.31.30.71.00.60.6-0.50.20.5
Patch foraging water rate 6 sec2.13.09.13.02.21.82.02.61.71.71.62.91.31.40.31.00.70.7-1.40.11.1
Seeking ratio, delayed vs. immediate footshock0.30.30.70.70.60.60.70.30.50.40.50.50.50.70.30.40.80.8-0.2-0.80.3
Distance traveled before self-admin0.81.12.6-1.6-1.2-1.2-1.3-1.3-1.2-1.3-1.1-1.1-1.0-1.0-1.0-0.8-0.7-0.70.2-0.10.0
Distance traveled after self-admin2.73.34.8-1.3-2.0-2.1-2.00.2-2.0-2.1-2.20.5-2.2-2.0-2.1-2.2-1.9-1.9-1.7-1.01.9
Extensor digitorum longus weight6.224.337.04.55.75.95.70.86.15.65.8-0.15.85.85.75.54.64.63.83.0-4.3
Bone: elastic displacement5.46.29.8-3.1-3.1-3.1-3.0-1.9-3.0-3.0-3.0-1.2-2.9-2.8-2.7-2.5-1.7-1.7-1.0-1.91.7
Bone: elastic work1.52.04.7-0.6-1.3-1.6-1.20.2-1.5-1.3-1.51.0-1.6-1.5-1.6-1.5-0.8-0.8-1.8-1.72.2
Bone: endosteal estimation2.14.614.53.72.52.42.33.82.22.41.93.51.61.41.30.9-0.2-0.2-1.41.00.7
Bone: endosteal perimeter2.34.914.13.72.72.72.53.42.52.72.22.92.01.81.81.40.40.4-0.81.1-0.0
Epididymis fat weight1.34.412.81.1-1.0-1.2-0.92.8-1.3-1.3-1.53.1-1.8-1.6-2.1-2.2-2.1-2.1-3.6-1.83.6
Delta time in closed arm before/after self-admin0.30.32.70.20.0-0.1-0.10.3-0.1-0.0-0.20.6-0.2-0.1-0.3-0.30.70.7-0.5-1.70.4
Delta time in open arm before/after self-admin2.52.53.6-1.2-1.7-1.7-1.80.3-1.6-1.9-1.90.3-1.9-1.8-1.8-1.9-1.9-1.9-1.3-0.11.4
Diff in mean of infusions in LGA sessions0.91.12.01.01.41.31.30.41.21.21.20.31.31.31.11.11.11.10.70.2-0.8
Delay discount exponential model param0.60.61.3-1.2-1.0-1.1-1.0-0.5-0.9-0.9-0.9-0.6-0.8-0.7-0.8-0.8-0.9-0.90.1-0.2-0.0
Extinction: sum of active levers before priming2.22.43.81.81.91.91.90.91.81.71.70.81.71.81.51.52.02.00.4-0.4-0.4
Active lever presses in extinction session 60.70.72.70.3-0.3-0.5-0.21.3-0.5-0.2-0.41.1-0.5-0.6-0.6-0.6-1.7-1.7-1.10.41.0
Bone: final force3.65.718.14.32.72.52.74.12.52.52.14.01.81.71.41.10.50.5-1.80.61.2
Bone: final moment3.86.219.74.42.72.52.74.42.52.52.14.41.81.61.31.00.40.4-2.00.61.4
Food consumed during 24 hour testing period0.81.05.11.50.60.30.61.70.20.30.12.3-0.10.2-0.2-0.4-0.1-0.1-1.8-0.91.9
Glucose0.10.20.5-0.4-0.6-0.5-0.5-0.2-0.5-0.7-0.5-0.3-0.5-0.3-0.3-0.4-0.4-0.4-0.10.20.2
Heart weight0.40.73.30.7-0.1-0.2-0.11.80.10.0-0.31.6-0.4-0.3-0.2-0.7-1.1-1.1-1.10.70.8
Delay discount hyperbolic model param0.60.71.3-1.1-1.0-1.1-1.0-0.4-0.9-1.0-1.0-0.5-0.9-0.8-0.9-0.9-0.9-0.9-0.1-0.50.2
Intermittent access intake day 1-15 change0.51.02.20.3-0.6-0.5-0.51.4-0.6-0.7-0.81.4-0.9-0.8-1.0-1.1-1.5-1.5-1.50.11.4
Intermittent access intake escalation0.30.62.40.7-0.00.1-0.01.6-0.0-0.1-0.21.4-0.3-0.3-0.5-0.6-1.1-1.1-1.10.50.9
Intermittent access intake escalation 20.40.51.50.3-0.3-0.1-0.30.9-0.2-0.3-0.41.0-0.4-0.3-0.6-0.6-1.2-1.2-1.00.50.7
Intermitt. access day 1 inactive lever presses0.10.31.9-0.4-0.3-0.2-0.1-0.8-0.3-0.2-0.1-0.7-0.1-0.20.00.10.90.90.3-1.4-0.2
Intermitt. access day 15 inactive lever presses0.20.42.0-0.2-0.4-0.2-0.40.5-0.4-0.3-0.30.2-0.4-0.6-0.3-0.3-1.2-1.2-0.31.40.2
Intermitt. access escalation Index1.21.73.00.01.11.11.1-1.51.21.01.3-1.41.41.51.31.61.61.61.70.4-1.6
Intermittent access day 1 total infusions0.81.32.9-1.4-1.5-1.7-1.5-0.6-1.5-1.3-1.3-0.7-1.3-1.5-1.0-1.1-0.6-0.6-0.2-1.30.1
Intermittent access day 15 total infusions0.60.81.5-0.7-1.2-1.1-1.10.2-1.0-1.0-1.1-0.0-1.1-1.2-0.9-1.1-0.8-0.8-0.5-0.80.4
Intermittent access terminal intake (last 3 days)0.60.81.5-0.9-1.2-1.2-1.2-0.1-1.0-0.9-1.1-0.2-1.0-1.2-0.8-1.1-1.1-1.1-0.4-0.70.1
Intermittent access total infusions0.91.12.1-1.1-1.4-1.4-1.4-0.3-1.2-1.1-1.3-0.4-1.2-1.4-0.9-1.2-0.8-0.8-0.3-1.00.1
Intermittent access day 1 locomotion1.51.94.8-1.3-1.6-1.8-1.6-0.3-1.7-1.5-1.6-0.3-1.6-1.8-1.4-1.5-0.3-0.3-0.7-2.20.7
Intermittent access day 15 total locomotion1.83.25.0-0.7-1.8-1.8-1.81.4-1.9-1.7-2.01.2-2.1-2.1-2.1-2.2-1.9-1.9-2.0-1.11.8
Intermittent access total locomotion2.83.35.4-1.7-2.2-2.3-2.2-0.2-2.3-2.1-2.2-0.2-2.2-2.3-2.0-2.1-1.2-1.2-1.1-1.91.0
Intermittent access standard deviation1.02.13.7-0.4-1.4-1.4-1.40.8-1.3-1.4-1.61.1-1.6-1.7-1.7-1.8-1.9-1.9-1.80.11.6
Left kidney weight0.73.110.22.82.02.22.03.22.11.81.72.41.51.60.51.0-0.1-0.1-0.71.20.2
Right kidney weight2.09.022.14.73.73.83.74.13.73.43.23.33.03.12.32.30.90.9-0.52.1-0.2
Cocaine induced anxiety0.60.93.51.70.90.80.91.90.91.00.71.70.60.70.40.2-0.0-0.0-0.8-0.10.5
Post-drug Anxiety1.11.15.01.90.90.70.92.20.60.90.52.20.40.30.1-0.0-0.4-0.4-1.4-0.41.0
Baseline Anxiety0.20.20.40.50.70.60.60.00.30.50.60.30.50.40.30.50.60.6-0.0-0.50.0
Tail length0.20.63.00.5-0.4-0.3-0.51.7-0.2-0.1-0.50.8-0.5-0.70.0-0.8-1.5-1.5-0.70.70.0
Length with tail0.52.48.82.91.51.61.63.01.51.61.22.51.00.91.20.50.20.2-1.3-0.10.6
Length without tail2.06.319.74.42.92.93.13.32.52.82.43.62.12.11.61.51.71.7-1.6-0.81.2
Times rat made contact with spout0.20.20.60.3-0.2-0.1-0.10.5-0.2-0.4-0.30.7-0.3-0.2-0.4-0.40.10.1-0.8-0.50.7
Lifetime Intake1.82.24.1-1.5-1.9-2.0-1.9-0.4-1.8-1.6-1.8-0.4-1.7-2.0-1.4-1.7-1.2-1.2-0.7-1.40.5
Liver weight, left3.45.617.74.22.62.52.74.22.52.52.13.81.91.61.31.10.10.1-1.70.60.8
Liver weight, right1.01.89.32.21.11.01.13.01.01.10.72.70.60.30.40.0-0.7-0.7-1.40.60.9
Locomotor activity0.40.61.5-1.2-1.1-1.0-1.0-0.5-0.9-0.9-0.9-0.6-0.8-0.7-0.4-0.7-0.9-0.90.10.20.1
Locomotor testing distance1.01.84.1-2.0-1.9-1.7-1.7-1.0-1.5-1.7-1.5-1.2-1.4-1.4-1.0-1.2-1.2-1.20.10.00.0
Locomotor testing rearing0.91.83.2-1.7-1.6-1.4-1.70.0-1.2-1.6-1.6-0.6-1.4-1.4-1.4-1.5-1.8-1.8-0.10.90.0
Locomotion in novel chamber2.12.76.42.52.01.92.01.92.02.21.81.51.81.51.71.40.50.5-0.01.2-0.6
Locomotion in novel chamber post-restriction0.30.41.60.5-0.2-0.4-0.10.8-0.5-0.2-0.41.1-0.5-0.5-0.5-0.6-0.5-0.5-1.2-0.51.3
Fecal boli incidents, locomotor time 11.62.45.4-0.9-1.7-1.6-1.50.2-1.7-1.7-1.70.5-1.8-1.7-1.8-1.8-1.0-1.0-1.6-2.31.8
Change in fecal boli incidents, locomotor task0.60.61.10.10.70.50.6-0.50.60.90.8-0.50.80.80.91.00.70.71.00.9-0.9
Time >=10cm from walls, locomotor time 10.70.72.8-0.7-1.0-0.9-1.0-0.4-1.0-0.8-1.0-0.2-1.0-1.1-0.5-0.9-0.4-0.4-0.5-1.70.6
Bouts of movement, locomotor time 10.10.20.8-0.20.20.10.2-0.80.00.10.3-0.20.20.20.00.40.70.70.1-0.90.2
Total resting periods, locomotor time 10.30.31.7-0.9-0.5-0.6-0.4-1.3-0.6-0.5-0.4-0.6-0.4-0.4-0.5-0.10.20.20.1-1.00.3
Rest time, locomotor task time 10.40.51.1-1.0-0.9-1.0-0.9-0.8-1.0-0.7-0.8-0.5-0.8-0.8-0.7-0.6-0.5-0.5-0.2-0.10.4
Distance moved, locomotor task time 10.10.10.30.10.10.20.2-0.40.20.20.3-0.50.30.20.40.40.50.50.50.6-0.6
Vertical activity count, locomotor time 10.51.11.91.11.21.41.20.71.31.21.20.21.21.11.31.00.50.50.81.3-1.0
Time >=10cm from walls, locomotor time 20.40.61.1-0.7-1.0-0.9-0.9-0.3-0.8-0.8-0.9-0.1-0.8-1.1-0.7-0.8-1.0-1.0-0.40.00.4
Bouts of movement, locomotor time 21.21.93.51.81.81.81.71.01.81.91.51.11.51.31.71.20.90.90.20.9-0.3
Total resting periods, locomotor time 21.52.74.81.92.12.02.01.02.12.21.90.91.81.62.01.51.01.00.51.7-0.7
Rest time, locomotor task time 20.10.10.6-0.4-0.1-0.4-0.1-0.8-0.3-0.0-0.1-0.5-0.1-0.0-0.10.1-0.2-0.20.30.8-0.0
Distance moved, locomotor task time 20.00.10.3-0.3-0.20.1-0.0-0.40.1-0.20.0-0.50.1-0.00.10.20.20.20.40.2-0.3
Vertical activity count, locomotor time 20.10.20.50.30.40.70.40.40.60.30.40.10.40.40.50.30.40.40.20.1-0.2
Light reinforcement 10.30.71.9-1.2-0.8-0.8-0.7-1.4-1.1-0.9-0.5-1.1-0.5-0.5-1.2-0.20.90.90.3-1.0-0.0
Light reinforcement 20.10.10.40.30.50.60.3-0.10.20.30.4-0.10.40.7-0.30.50.50.50.20.3-0.2
Bone: marrow area2.04.314.23.62.32.32.23.82.12.31.73.51.51.31.20.8-0.3-0.3-1.41.00.8
Bone: maximum diameter0.71.23.92.01.21.41.21.81.41.31.11.31.00.81.00.70.10.1-0.30.7-0.3
Bone: maximum force4.78.323.44.83.63.23.63.93.23.42.94.12.62.52.11.91.21.2-1.30.80.8
Bone: maximum moment4.98.525.15.03.63.23.54.23.23.42.94.52.52.42.01.81.01.0-1.60.81.0
Mean time between licks in bursts0.41.02.3-0.7-1.1-1.3-0.8-1.1-1.3-0.7-1.0-0.1-1.1-1.2-0.9-0.7-0.3-0.3-0.9-1.51.4
Mean num. licks in bursts0.50.84.40.40.10.1-0.12.10.3-0.3-0.41.5-0.4-0.1-0.6-0.8-1.2-1.2-1.00.80.9
Cd content in liver0.30.30.7-0.4-0.7-0.6-0.6-0.3-0.7-0.6-0.6-0.1-0.7-0.8-0.6-0.60.10.1-0.4-0.80.4
Co content in liver0.30.32.3-0.10.20.50.10.10.4-0.10.2-0.80.30.50.30.2-0.1-0.10.81.5-0.9
Cu content in liver0.40.52.40.40.30.4-0.01.40.40.20.00.60.10.10.1-0.3-1.2-1.2-0.11.6-0.4
Fe content in liver0.81.02.0-1.3-1.4-1.2-1.4-0.8-1.1-1.0-1.1-1.1-1.0-1.3-0.7-0.9-0.8-0.80.00.2-0.4
K content in liver0.10.10.7-0.3-0.20.1-0.20.10.1-0.1-0.1-0.40.00.20.1-0.0-0.4-0.40.30.8-0.5
Mg content in liver0.20.20.5-0.4-0.6-0.4-0.4-0.0-0.5-0.5-0.5-0.0-0.5-0.4-0.5-0.5-0.7-0.7-0.4-0.20.6
Mn content in liver0.20.20.7-0.20.40.30.4-0.60.30.30.4-0.40.50.80.30.60.20.20.70.6-0.3
Na content in liver0.20.21.10.30.30.50.00.90.50.20.10.20.20.40.2-0.1-0.4-0.4-0.01.1-0.5
Rb content in liver0.91.01.7-1.0-1.3-1.1-1.20.0-1.0-1.3-1.2-0.5-1.1-1.3-0.9-1.1-1.2-1.2-0.20.10.0
Se content in liver1.61.93.7-1.8-1.9-1.9-1.8-1.2-1.7-1.8-1.6-1.2-1.5-1.4-1.4-1.2-0.8-0.8-0.1-0.60.2
Sr content in liver0.30.21.30.60.50.30.21.10.20.40.21.00.20.3-0.1-0.1-0.4-0.4-0.40.40.1
Zn content in liver1.21.31.9-1.0-1.3-1.3-1.3-0.2-1.4-1.2-1.3-0.1-1.3-1.4-1.2-1.3-1.1-1.1-0.8-0.90.9
Bone: minimum diameter2.64.813.73.72.72.52.62.92.52.72.32.82.11.81.81.50.90.9-0.80.80.1
Time in familiar zone, hab. session 10.10.10.50.20.20.00.4-0.40.1-0.00.1-0.00.10.30.10.20.60.6-0.1-0.70.6
Time in novel zone, hab. session 10.20.20.70.10.20.40.1-0.20.30.50.4-0.40.40.10.50.40.30.30.50.4-0.8
Total zone transitions, hab. session 11.11.63.4-0.30.90.70.9-1.80.70.81.2-1.61.21.31.11.61.61.61.80.3-1.4
Total locomotion distance, hab. session 10.20.31.6-0.9-0.4-0.6-0.3-1.2-0.6-0.3-0.2-0.8-0.2-0.1-0.20.10.40.40.4-0.60.1
Locomotion velocity, hab. session 10.10.21.1-0.8-0.3-0.5-0.2-1.1-0.5-0.2-0.1-0.6-0.1-0.1-0.20.10.40.40.3-0.50.2
Time in familiar zone, hab. session 20.60.62.41.30.90.61.01.20.60.50.51.50.40.60.10.20.40.4-0.8-0.71.0
Time in novel zone, hab. session 20.70.73.0-1.4-0.9-0.5-0.9-1.4-0.6-0.5-0.5-1.7-0.4-0.6-0.1-0.2-0.4-0.41.00.7-1.1
Total zone transitions, hab. session 20.10.10.9-0.6-0.3-0.6-0.3-0.9-0.6-0.3-0.2-0.4-0.2-0.1-0.4-0.00.00.00.2-0.30.1
Total locomotion distance, hab. session 20.40.51.1-0.9-0.8-1.0-0.8-1.0-1.0-0.7-0.7-0.5-0.7-0.7-0.7-0.5-0.3-0.3-0.2-0.90.5
Locomotion velocity, hab. session 20.40.51.0-0.7-0.8-1.0-0.7-0.7-1.0-0.6-0.7-0.2-0.7-0.7-0.8-0.6-0.3-0.3-0.4-0.90.6
Novel to familiar place preference ratio2.22.43.41.41.71.81.70.01.81.81.9-0.11.81.81.71.81.61.61.20.9-1.5
Novelty place preference1.71.92.61.11.51.51.5-0.21.51.51.6-0.31.61.51.51.61.51.51.20.7-1.4
Time in novel zone, NPP test1.71.82.50.91.41.41.4-0.41.51.41.6-0.41.61.51.51.61.51.51.30.7-1.5
Total zone transitions, NPP test0.91.44.8-2.0-1.3-1.4-1.2-2.2-1.5-1.3-0.9-1.7-0.9-0.7-0.9-0.4-0.1-0.10.6-0.8-0.1
Total locomotion distance, NPP test2.12.85.8-2.4-2.0-2.2-1.9-2.3-2.2-1.9-1.7-1.4-1.7-1.6-1.7-1.2-0.5-0.5-0.2-1.80.8
Locomotion velocity, NPP test1.62.34.3-2.0-1.8-2.0-1.7-1.8-2.1-1.7-1.6-0.9-1.6-1.4-1.6-1.1-0.5-0.5-0.5-1.81.1
Intraocular pressure3.34.78.2-2.9-2.7-2.7-2.7-1.5-2.5-2.7-2.6-1.3-2.5-2.5-2.0-2.2-1.9-1.9-0.4-0.40.9
Delta distance traveled before/after self-admin3.03.16.70.0-1.4-1.4-1.32.0-1.3-1.4-1.72.0-1.8-1.6-1.8-2.1-2.1-2.1-2.6-0.92.5
Delta ambulatory time before/after self-admin2.63.26.1-0.2-1.5-1.5-1.41.7-1.4-1.4-1.71.8-1.8-1.7-1.8-2.1-2.5-2.5-2.4-0.52.3
Parametrial fat weight1.33.06.5-0.9-1.8-1.7-1.4-0.3-2.1-2.1-1.80.4-1.9-1.8-2.3-1.7-1.0-1.0-1.8-2.62.5
Pavlov. Cond. lever latency1.11.32.4-0.9-1.3-1.3-1.3-0.1-1.4-1.0-1.30.3-1.4-1.5-1.3-1.3-1.2-1.2-1.0-0.61.1
Pavlov. Cond. magazine entry latency1.72.23.91.41.71.81.70.52.01.61.70.21.71.71.71.61.31.31.01.1-1.2
Pavlov. Cond. change in total contacts3.03.25.11.62.12.22.10.42.21.82.1-0.12.12.22.12.01.81.81.31.0-1.5
Pavlov. Cond. index score2.93.75.91.62.22.32.10.42.41.92.2-0.32.32.42.22.11.71.71.61.5-1.9
Pavlov. Cond. latency score2.63.35.31.52.02.22.00.42.31.82.1-0.32.12.32.12.01.61.61.51.4-1.9
Pavlov. Cond. lever contacts1.11.32.30.91.21.41.20.31.41.01.3-0.21.41.51.31.21.11.11.00.8-1.2
Pavlov. Cond. magazine entry number1.21.52.8-1.2-1.4-1.5-1.4-0.5-1.7-1.3-1.4-0.1-1.4-1.4-1.5-1.3-1.0-1.0-0.8-1.01.1
Pavlov. Cond. intertrial magazine entries3.13.76.7-2.6-2.3-2.5-2.3-1.7-2.5-2.5-2.2-1.2-2.1-1.9-2.2-1.7-1.0-1.0-0.4-1.41.1
Pavlov. Cond. lever-magazine prob. diff.3.03.75.91.72.22.32.20.42.42.02.3-0.12.32.42.22.11.81.81.41.4-1.7
Pavlov. Cond. response bias0.70.91.51.01.11.11.10.41.21.01.10.11.11.11.11.01.01.00.60.6-0.8
Pavlov. Cond. lever latency1.42.03.30.81.71.61.50.21.81.71.6-0.11.61.81.41.50.80.81.31.8-1.3
Pavlov. Cond. magazine entry latency1.61.98.0-0.4-1.5-1.4-1.2-0.3-1.7-1.2-1.40.4-1.5-1.7-1.2-1.3-0.1-0.1-1.7-2.81.8
Pavlov. Cond. change in total contacts0.71.11.71.31.11.21.30.11.11.01.2-0.01.21.11.21.21.31.30.5-0.2-0.6
Pavlov. Cond. index score1.01.34.8-0.3-1.3-1.3-1.0-0.2-1.4-1.2-1.20.2-1.3-1.5-1.0-1.1-0.2-0.2-1.4-2.21.3
Pavlov. Cond. latency score1.01.34.5-0.3-1.4-1.2-1.1-0.3-1.4-1.2-1.20.1-1.2-1.4-1.0-1.1-0.2-0.2-1.2-2.11.2
Pavlov. Cond. lever contacts1.42.03.6-0.6-1.7-1.6-1.4-0.1-1.8-1.6-1.60.3-1.6-1.8-1.4-1.5-0.8-0.8-1.5-1.91.5
Pavlov. Cond. magazine entry number0.60.74.2-0.10.80.80.5-0.01.00.70.8-0.50.80.90.70.8-0.0-0.01.22.0-1.2
Pavlov. Cond. intertrial magazine entries1.62.45.4-1.5-1.7-1.5-1.80.7-1.3-1.9-1.80.0-1.7-1.6-1.7-1.9-2.3-2.3-0.70.80.5
Pavlov. Cond. lever-magazine prob. diff.0.70.93.9-0.1-1.1-1.0-0.8-0.2-1.2-1.0-0.90.2-1.0-1.2-0.8-0.9-0.1-0.1-1.1-2.01.1
Pavlov. Cond. response bias1.52.06.3-0.3-1.5-1.5-1.20.0-1.8-1.5-1.50.6-1.6-1.7-1.4-1.4-0.5-0.5-1.8-2.51.8
Time in closed arm before self-admin2.02.54.21.01.61.91.8-0.21.91.91.9-0.41.91.92.11.91.51.51.40.7-1.5
Time in closed arm after self-admin1.61.73.30.61.21.41.3-0.71.31.31.4-0.61.41.51.41.51.81.81.3-0.4-1.2
Time in open arm before self-admin0.50.61.7-0.40.10.10.2-1.3-0.00.20.4-1.30.40.40.50.71.21.21.1-0.6-0.9
Time in open arm after self-admin0.30.30.6-0.6-0.6-0.7-0.6-0.3-0.6-0.8-0.6-0.4-0.6-0.6-0.4-0.5-0.5-0.5-0.20.10.3
Bone: periosteal estimation3.26.720.44.53.02.92.94.42.82.92.43.92.21.91.81.30.20.2-1.41.40.4
Bone: periosteal perimeter3.56.116.34.03.03.12.93.52.93.02.62.82.42.22.31.80.90.9-0.51.2-0.4
Bone: post-yield work1.72.68.32.91.81.61.82.61.51.91.42.81.21.00.90.70.20.2-1.20.30.8
Progressive ratio test 1 active lever presses4.96.010.8-3.0-3.0-3.3-3.1-1.7-3.1-3.0-2.9-1.3-2.8-2.9-2.4-2.5-1.3-1.3-0.7-2.41.0
Progressive ratio test 1 breakpoint5.16.211.0-2.9-3.1-3.3-3.1-1.6-3.1-3.0-3.0-1.2-2.9-2.9-2.4-2.6-1.3-1.3-0.8-2.61.2
Progressive ratio test 1 inactive lever presses0.30.40.8-0.8-0.7-0.6-0.7-0.7-0.8-0.8-0.6-0.7-0.6-0.8-0.4-0.4-0.3-0.30.1-0.9-0.0
Progressive ratio test 2 active lever presses1.01.22.2-1.2-1.4-1.4-1.4-0.3-1.3-1.3-1.3-0.5-1.2-1.5-0.9-1.1-1.1-1.1-0.2-0.60.1
Progressive ratio test 2 breakpoint0.70.81.6-1.1-1.2-1.2-1.2-0.3-1.2-1.1-1.1-0.6-1.0-1.3-0.7-0.9-0.8-0.80.0-0.5-0.1
Progressive ratio test 2 inactive lever presses1.01.73.3-0.9-1.4-1.5-1.40.4-1.5-1.4-1.40.3-1.4-1.6-1.2-1.5-1.8-1.8-1.0-0.60.8
Incentive Sensitization - Responses0.60.92.71.01.01.11.01.10.91.01.00.51.00.81.00.8-0.3-0.30.41.6-0.7
Incentive Sensitization - Breakpoint0.70.93.30.91.01.11.00.91.01.11.00.31.00.91.00.9-0.3-0.30.61.8-0.9
Sum of active levers in priming session hrs 5-60.00.00.1-0.3-0.0-0.10.1-0.3-0.1-0.00.1-0.30.10.00.10.2-0.1-0.10.40.4-0.2
Progressive ratio0.61.02.2-1.5-1.3-1.3-1.2-1.4-1.2-1.1-1.1-1.2-1.0-0.9-0.8-0.7-0.3-0.30.2-0.50.1
Food seeking constrained by brief footshock1.72.14.1-2.0-1.8-1.9-1.8-1.4-1.6-1.7-1.6-1.4-1.5-1.4-1.3-1.2-1.3-1.30.10.70.2
Seeking ratio, punishment vs. effort0.00.00.20.30.30.20.20.30.20.20.20.20.20.20.10.1-0.1-0.1-0.10.50.0
Retroperitoneal fat weight2.08.514.2-1.6-3.2-3.1-2.80.2-3.3-3.4-3.31.1-3.4-3.2-3.2-3.3-2.3-2.3-3.2-3.13.8
Reaction time number correct0.40.84.80.90.50.30.12.20.40.3-0.01.9-0.0-0.0-0.3-0.6-0.9-0.9-0.90.80.4
Reaction time mean minus median1.02.67.1-2.7-1.8-1.8-2.1-1.5-1.5-1.7-1.8-1.9-1.5-1.4-0.7-1.3-1.8-1.80.60.8-0.5
Reaction time mean minus median AUC0.61.65.2-2.3-1.2-1.4-1.5-1.6-1.0-1.2-1.2-1.8-1.0-0.8-0.4-0.8-1.3-1.30.91.0-0.6
Reaction time num false alarms0.50.72.5-1.5-0.8-0.7-0.9-1.6-0.9-0.7-0.7-1.3-0.6-0.7-0.0-0.30.20.20.5-1.0-0.1
Reaction time num false alarms AUC0.50.84.1-1.6-0.8-0.6-0.7-2.0-0.8-0.6-0.5-1.6-0.5-0.50.1-0.00.50.50.8-1.0-0.3
Reaction time trials correct on left0.40.84.80.90.50.30.12.20.40.3-0.01.9-0.0-0.0-0.3-0.6-0.9-0.9-0.90.80.4
Reaction time trials on left0.40.74.40.80.40.20.02.10.30.2-0.11.8-0.1-0.1-0.3-0.7-1.0-1.0-0.90.80.4
Reaction time mean0.40.61.1-0.9-0.9-1.1-1.0-0.1-0.8-0.7-0.9-0.5-0.8-0.9-0.3-0.8-0.9-0.9-0.10.4-0.1
Reaction time mean AUC0.20.40.8-0.7-0.7-0.8-0.80.0-0.6-0.5-0.7-0.3-0.6-0.7-0.2-0.7-0.9-0.9-0.10.6-0.1
Median of all reaction times0.10.20.4-0.0-0.5-0.6-0.40.5-0.4-0.2-0.50.2-0.4-0.6-0.1-0.6-0.5-0.5-0.40.20.1
Reaction time omissions3.04.411.0-3.3-2.6-2.4-2.8-2.3-2.3-2.5-2.3-2.6-2.0-2.0-1.6-1.7-1.5-1.50.80.5-0.6
Reaction time false alarm rate0.91.27.4-1.5-0.6-0.3-0.3-2.7-0.6-0.2-0.1-2.2-0.0-0.10.70.61.21.21.3-1.2-0.7
Reaction time premature initiation rate1.72.44.6-2.1-1.9-1.9-2.0-1.1-1.8-2.2-1.9-0.9-1.8-1.6-1.7-1.6-0.5-0.5-0.5-1.20.7
Reaction time premature initiations1.12.03.6-1.5-1.5-1.6-1.90.1-1.4-1.9-1.80.2-1.8-1.5-1.8-1.9-1.1-1.1-1.0-0.60.9
Std. dev. reaction times1.22.36.6-2.6-1.7-1.8-1.9-1.8-1.6-1.6-1.6-2.0-1.4-1.3-0.6-1.1-1.4-1.40.70.6-0.5
Reaction time trials completed0.40.74.40.80.40.20.02.10.30.2-0.11.8-0.1-0.1-0.3-0.7-1.0-1.0-0.90.80.4
Reaction time trials AUC0.40.85.11.10.80.50.42.30.70.50.21.90.20.2-0.1-0.4-0.8-0.8-0.80.90.3
Run reversals in cocaine runway, females0.30.31.20.4-0.00.2-0.01.10.10.0-0.20.8-0.2-0.1-0.1-0.4-0.9-0.9-0.5-0.30.4
Run reversals in cocaine runway, males1.11.14.8-0.70.40.30.2-0.70.50.40.5-1.70.70.80.90.8-0.1-0.11.92.2-2.0
Latency to leave start box in cocaine runway0.60.62.6-0.00.30.40.5-1.20.40.40.6-0.80.60.50.60.91.61.60.7-0.6-0.6
Latency to leave start box in cocaine runway, F0.60.73.2-1.1-0.4-0.3-0.2-1.8-0.3-0.2-0.0-1.60.10.10.20.41.21.21.1-0.5-0.8
Latency to leave start box in cocaine runway, M1.11.01.91.41.21.31.30.31.31.01.20.71.10.91.01.01.31.3-0.0-0.0-0.2
Std. dev. time between licks in bursts0.81.12.2-1.2-1.2-1.3-1.3-1.0-1.5-1.2-1.2-0.5-1.2-1.2-1.1-0.9-0.7-0.7-0.6-0.80.8
Total sessions with >9 infusions1.41.73.5-1.7-1.6-1.9-1.6-1.3-1.8-1.5-1.4-1.0-1.4-1.6-1.2-1.1-0.2-0.2-0.2-1.40.3
Short access day 1 total inactive lever presses1.01.32.6-1.5-1.4-1.6-1.4-1.2-1.5-1.3-1.3-0.8-1.3-1.3-1.0-1.1-0.4-0.4-0.2-1.30.3
Short access day 10 total inactive lever presses0.00.10.20.20.20.30.20.00.30.40.30.00.30.20.40.2-0.2-0.20.1-0.0-0.4
Short access day 1 total infusions1.62.14.0-1.2-1.7-2.0-1.7-0.0-1.8-1.5-1.7-0.0-1.7-1.9-1.5-1.7-1.3-1.3-0.9-1.00.7
Short access day 10 total infusions1.11.42.9-1.6-1.6-1.7-1.6-0.9-1.4-1.3-1.4-1.1-1.2-1.5-0.8-1.1-0.6-0.60.2-0.9-0.3
Short access total infusions3.13.96.9-2.0-2.4-2.6-2.5-0.7-2.4-2.2-2.4-0.6-2.3-2.6-2.0-2.2-1.5-1.5-0.9-1.70.8
Short access day 1 locomotion0.40.41.1-0.6-0.8-1.0-0.8-0.4-0.9-0.7-0.8-0.3-0.7-0.8-0.6-0.70.20.2-0.2-1.00.2
Short access day 10 total locomotion0.30.61.2-0.9-0.9-1.1-1.0-0.2-0.9-0.7-1.0-0.3-0.9-1.0-0.6-0.9-0.5-0.5-0.1-0.3-0.1
Short access total locomotion1.21.42.9-1.3-1.3-1.7-1.5-0.7-1.5-1.3-1.4-0.4-1.4-1.4-1.1-1.3-0.2-0.2-0.5-1.70.5
One hour access (0.3 mA shock)0.20.20.80.80.40.50.40.90.40.60.40.60.40.10.30.1-0.0-0.0-0.2-0.4-0.3
Compulsive drug intake0.50.61.20.70.91.11.00.10.81.01.00.00.90.71.00.90.40.40.50.6-0.5
One hour access (shock baseline)0.10.10.80.60.20.20.10.90.30.30.10.70.10.00.1-0.2-0.2-0.2-0.3-0.5-0.1
Social response proportion1.01.13.30.0-1.0-0.8-0.90.9-0.7-0.9-1.10.7-1.1-1.1-0.7-1.2-1.8-1.8-1.30.21.1
Social responses1.21.53.5-1.9-1.6-1.4-1.4-1.7-1.2-1.4-1.2-1.8-1.0-1.1-0.6-0.7-1.2-1.20.60.6-0.5
Social time0.71.03.10.7-0.3-0.2-0.21.5-0.2-0.1-0.41.5-0.5-0.7-0.5-0.8-1.8-1.8-1.50.81.1
Soleus weight0.31.02.81.71.11.31.01.71.11.00.81.50.70.70.70.40.40.4-0.8-0.20.5
Bone: stiffness7.111.530.15.54.34.04.24.03.94.23.74.03.43.22.92.71.71.7-0.81.30.1
Tibialis anterior weight7.224.533.93.85.45.75.5-0.45.85.25.7-1.45.85.75.85.75.15.14.62.8-5.0
Time to tail flick, vehicle, before self-admin0.50.51.2-1.1-0.9-0.8-0.8-1.0-0.7-0.7-0.6-0.8-0.6-0.8-0.5-0.4-0.6-0.60.10.3-0.1
Time to tail flick, vehicle, after self-admin0.40.50.80.60.70.60.80.00.80.80.9-0.10.90.70.90.90.80.80.60.3-0.9
Time to tail flick, test, before self-admin0.30.30.9-0.6-0.00.2-0.0-0.80.10.00.2-0.90.20.40.20.40.40.41.00.9-0.8
Time to tail flick, test, after self-admin0.40.40.80.80.80.90.70.70.80.90.70.60.70.60.70.60.60.60.1-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.20.21.30.80.50.30.51.10.40.40.40.80.40.40.30.20.00.0-0.3-0.10.0
Delta time to tail flick, test, before/after SA0.20.20.50.70.30.20.40.70.40.50.30.70.2-0.00.30.10.10.1-0.4-0.70.2
Tibia length1.43.918.23.81.61.41.74.31.41.51.03.80.70.50.5-0.0-0.1-0.1-2.4-0.51.6
Ambulatory time before self-admin1.01.63.4-1.9-1.4-1.5-1.6-1.5-1.5-1.6-1.4-1.0-1.3-1.2-1.4-1.1-0.6-0.6-0.1-0.80.4
Ambulatory time after self-admin3.54.15.9-1.6-2.2-2.3-2.30.2-2.2-2.2-2.40.5-2.4-2.2-2.3-2.4-2.3-2.3-1.8-1.01.9
Bone: tissue strength0.70.71.41.11.21.01.20.41.01.01.00.80.91.00.80.80.80.80.10.40.1
Total heroin consumption0.30.41.90.80.30.10.21.2-0.1-0.0-0.01.4-0.2-0.1-0.3-0.3-0.3-0.3-1.1-0.61.0
Bone: trabecular number1.11.88.12.11.41.21.12.81.31.10.82.50.70.90.30.1-0.7-0.7-1.20.90.8
Bone: trabecular spacing0.30.52.1-0.8-0.4-0.3-0.2-1.4-0.4-0.2-0.1-1.40.0-0.10.30.30.80.80.8-0.4-0.7
Bone: trabecular thickness0.70.91.70.61.11.11.00.11.31.01.1-0.21.11.30.91.10.50.51.01.1-0.9
Bone: trabecular tissue density2.43.57.41.11.81.61.9-1.61.52.12.1-0.92.01.92.12.42.72.71.6-0.7-1.3
Water consumed over 24 hours0.70.92.00.1-0.6-0.6-0.71.3-0.6-0.8-0.91.3-0.9-0.8-1.0-1.2-1.1-1.1-1.4-0.31.3
Number of responses in last shaping day0.30.31.1-0.10.20.30.2-0.80.20.10.3-0.60.30.20.20.41.01.00.6-1.1-0.5