Hub : Genes

Krt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Krt1 0.12 0.03 0.0e+00 0.27 0.3 0.29 0.29 2.2e-40 1.5e-45 2.3e-44 1.1e-43
2 pVTA gene expression Krt1 0.2 0.1 1.3e-15 0.21 0.2 0.2 0.21 6.7e-17 1.0e-15 5.8e-16 8.6e-17
3 Brain gene expression Krt1 0.13 0.07 7.3e-13 0.15 0.14 0.14 0.15 7.0e-14 4.1e-13 2.8e-13 4.9e-14
4 Adipose gene expression Krt1 0.04 0.02 1.9e-05 0.04 0.04 0.04 0.04 1.6e-05 2.8e-05 2.0e-05 6.5e-05
5 PL gene expression Krt1 0.11 0.06 6.6e-15 0.15 0.14 0.15 0.15 2.9e-16 3.8e-15 5.4e-16 3.5e-16
6 RMTg gene expression Krt1 0.16 0.1 1.7e-03 0.06 0.02 -0 0.04 1.0e-02 1.0e-01 4.4e-01 2.7e-02
7 IC gene expression Krt1 0.06 0.04 3.7e-03 0.07 0.06 0.04 0.05 8.4e-04 2.4e-03 6.5e-03 3.0e-03
8 BLA gene expression Krt1 0.23 0.1 1.2e-13 0.27 0.25 0.25 0.27 1.8e-14 1.2e-13 1.3e-13 2.0e-14
9 IL gene expression Krt1 0.12 0.08 9.9e-03 0.03 0.01 0 0 6.1e-02 1.9e-01 3.1e-01 3.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.20.30.5-0.30.5-0.3-0.4-0.3-0.3-0.5-0.4
Area under the delay curve0.10.10.30.4-0.30.5-0.2-0.5-0.3-0.4-0.40.0
BMI with tail1.75.97.12.7-2.62.5-2.0-2.3-2.4-2.5-2.3-2.6
BMI without tail0.42.12.91.5-1.51.4-1.2-1.1-1.5-1.7-1.2-1.7
Body weight0.41.62.91.3-1.31.4-0.6-0.9-1.4-1.4-1.0-1.7
Weight adjusted by age0.51.62.51.1-1.51.30.4-1.4-1.1-1.1-1.5-1.6
Bone surface0.20.40.80.9-0.70.6-0.9-0.7-0.5-0.4-0.6-0.6
Bone volume0.40.81.11.0-0.90.9-1.1-0.8-0.7-0.7-0.9-0.9
Breakpoint value in progressive ratio session0.10.21.40.4-0.3-0.0-1.2-0.1-0.4-0.1-0.10.1
Number of licking bursts0.00.10.30.1-0.20.1-0.5-0.1-0.2-0.2-0.2-0.4
Context. condit. distance diff. score0.10.10.2-0.20.2-0.2-0.40.50.20.20.3-0.0
Locomotion velocity, session 14.55.16.0-2.52.3-2.32.32.42.32.32.41.5
Locomotion distance, session 10.70.91.7-1.10.8-0.91.30.91.00.90.80.3
Locomotion velocity, session 22.93.56.0-1.91.7-1.82.41.91.71.81.91.4
Locomotion distance, session 20.91.32.1-1.31.1-1.11.51.21.01.11.10.7
Locomotion velocity, session 35.56.47.1-2.62.6-2.62.42.62.62.62.71.9
Locomotion distance, session 35.25.96.4-2.52.5-2.52.22.52.52.42.52.2
Stereotopy head waving bouts, day 31.92.22.71.5-1.61.4-1.7-1.3-1.4-1.5-1.4-1.6
Stereotopy head waving duration, day 30.10.10.20.3-0.30.2-0.4-0.1-0.2-0.3-0.1-0.5
Locomotion velocity, session 71.01.11.6-1.11.0-1.10.21.01.21.20.91.3
Locomotion distance, session 73.03.94.8-2.11.9-2.11.71.82.22.11.72.1
Stereotopy head waving bouts, day 74.14.85.62.2-2.12.2-2.4-2.1-2.1-2.1-2.2-2.3
Stereotopy head waving duration, day 72.22.83.61.7-1.51.6-1.8-1.5-1.6-1.6-1.6-1.9
Locomotion velocity, session 80.20.30.6-0.50.5-0.60.10.80.50.50.70.0
Locomotion distance, session 81.72.43.0-1.71.6-1.61.41.71.61.61.51.1
Degree of sensitization distance0.60.70.80.8-0.80.8-0.8-0.9-0.8-0.8-0.9-0.7
Degree of sensitization stereotypy2.52.83.41.7-1.51.6-1.9-1.7-1.6-1.6-1.7-1.8
Conditioned locomotion0.70.82.7-0.80.5-0.50.71.40.60.51.60.2
Cocaine response after cond. corrected0.10.10.40.2-0.30.50.2-0.2-0.5-0.5-0.2-0.6
Cocaine response after cond. not corrected0.00.00.2-0.0-0.10.20.4-0.1-0.1-0.1-0.0-0.3
Cocaine response before conditioning1.11.32.1-1.11.0-1.20.51.01.41.50.91.3
Saline control response0.10.10.2-0.30.1-0.1-0.20.40.20.20.50.3
Bone: connectivity density0.10.10.3-0.20.4-0.40.30.20.50.50.20.5
Bone: cortical apparent density1.62.63.61.5-1.91.8-0.9-1.5-1.6-1.7-1.5-1.7
Bone: cortical area0.71.11.41.2-1.11.1-0.8-1.1-1.0-1.0-1.1-0.9
Bone: cortical porosity1.61.82.5-1.41.3-1.31.41.61.11.21.61.1
Bone: cortical porosity1.51.72.0-1.31.3-1.31.31.41.11.21.41.1
Bone: cortical thickness0.40.61.00.8-0.80.8-0.3-0.9-0.8-0.8-1.0-0.6
Bone: cortical thickness0.50.62.8-0.70.7-0.61.70.30.70.60.30.7
Bone: cortical tissue density1.52.33.41.4-1.81.8-0.8-1.4-1.6-1.6-1.4-1.6
Condit. Reinf. active minus inactive responses0.30.30.6-0.60.5-0.50.50.80.20.40.70.3
Condit. Reinf. active-inactive response ratio0.40.40.6-0.70.8-0.60.70.70.30.60.60.7
Condit. Reinf. active responses0.60.81.5-1.00.8-0.81.11.20.60.81.10.5
Condit. Reinf. inactive responses0.60.81.5-1.00.6-0.71.21.20.70.71.20.3
Incentive salience index mean0.00.00.1-0.10.2-0.10.00.3-0.20.00.2-0.0
Condit. Reinf. lever presses0.50.70.90.8-0.80.8-0.9-0.8-1.0-0.9-0.9-0.9
Condit. Reinf. active minus inactive responses1.01.62.21.3-1.31.2-1.2-1.3-1.3-1.3-1.5-1.0
Condit. Reinf. active-inactive response ratio0.30.50.70.7-0.70.7-0.7-0.8-0.8-0.8-0.8-0.5
Condit. Reinf. active responses1.21.72.51.3-1.41.2-1.6-1.3-1.2-1.2-1.5-1.0
Condit. Reinf. inactive responses0.10.20.40.3-0.60.3-0.7-0.3-0.3-0.2-0.5-0.5
Condit. Reinf. lever presses0.30.40.7-0.70.6-0.80.30.70.60.60.60.9
Condit. Reinf. lever reinforcers received0.40.61.10.7-0.90.6-1.0-0.7-0.7-0.7-0.9-0.5
Conditioned reinforcement - actives0.10.20.6-0.20.1-0.1-0.80.10.70.60.20.5
Conditioned reinforcement - inactives0.10.30.7-0.50.4-0.40.30.30.70.50.20.9
Conditioned locomotion0.30.51.3-0.40.4-0.4-0.50.41.21.10.40.9
Patch foraging indifference point 0 sec0.20.51.0-0.80.7-0.70.20.51.00.80.60.8
Patch foraging indifference point AUC0.30.71.10.6-1.00.9-0.6-0.6-1.1-1.0-0.7-0.7
Delay disc. indifference point, 0s delay0.10.10.30.1-0.30.40.5-0.2-0.3-0.2-0.30.1
Delay disc. indifference point, 16s delay0.10.10.20.3-0.30.4-0.4-0.5-0.5-0.2-0.30.3
Delay disc. indifference point, 2s delay5.86.57.22.6-2.22.6-2.4-2.7-2.7-2.6-2.5-2.5
Delay disc. indifference point, 24s delay0.10.10.20.3-0.50.3-0.4-0.4-0.1-0.2-0.20.1
Delay disc. indifference point, 4s delay0.20.20.40.50.10.6-0.5-0.5-0.6-0.5-0.4-0.0
Delay disc. indifference point, 8s delay0.20.30.5-0.50.4-0.50.60.50.70.60.50.7
Indifference point function ln k0.10.20.4-0.20.7-0.30.40.50.50.40.6-0.3
Indifference point function log k0.10.20.4-0.20.7-0.30.40.50.50.40.6-0.3
Patch foraging total patch changes 0 sec0.41.21.9-1.21.1-1.10.71.01.41.21.01.1
Patch foraging total patch changes 12 sec0.00.00.1-0.3-0.10.1-0.20.20.1-0.10.10.4
Patch foraging total patch changes 18 sec0.10.20.4-0.50.2-0.5-0.10.20.60.60.20.6
Patch foraging total patch changes 24 sec0.00.10.7-0.1-0.00.1-0.8-0.10.30.2-0.10.4
Patch foraging total patch changes 6 sec0.00.10.2-0.1-0.40.2-0.2-0.2-0.0-0.2-0.30.4
Patch foraging time to switch 0 sec0.10.30.60.5-0.50.5-0.3-0.7-0.5-0.6-0.8-0.4
Patch foraging water rate 0 sec0.00.10.1-0.10.3-0.2-0.20.20.20.20.4-0.1
Patch foraging water rate 12 sec0.41.62.3-1.11.2-1.40.81.41.41.51.40.5
Patch foraging water rate 18 sec0.00.10.2-0.10.3-0.0-0.10.30.40.30.3-0.1
Patch foraging water rate 24 sec0.10.20.60.5-0.60.5-0.7-0.1-0.2-0.2-0.0-0.6
Patch foraging water rate 6 sec0.40.50.9-0.50.9-0.90.00.90.90.80.80.2
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.1-0.1-0.30.40.20.10.00.20.2
Distance traveled before self-admin0.00.00.3-0.00.10.30.00.00.10.10.00.5
Distance traveled after self-admin1.62.94.4-1.51.8-1.40.61.62.02.11.72.1
Extensor digitorum longus weight7.329.232.85.6-5.65.5-4.5-5.2-5.6-5.6-5.0-5.7
Bone: elastic displacement4.65.97.8-2.62.4-2.42.02.82.32.42.62.1
Bone: elastic work2.73.54.7-1.91.9-1.82.22.01.71.81.81.8
Bone: endosteal estimation0.10.40.80.8-0.60.6-0.9-0.5-0.4-0.4-0.5-0.6
Bone: endosteal perimeter0.51.21.81.3-1.11.1-1.1-1.0-1.0-1.0-1.0-1.1
Epididymis fat weight1.99.510.8-3.13.3-3.13.23.22.93.03.03.0
Delta time in closed arm before/after self-admin0.20.20.70.1-0.00.3-0.90.00.70.50.10.4
Delta time in open arm before/after self-admin2.73.24.2-1.91.6-1.92.01.61.81.91.61.7
Diff in mean of infusions in LGA sessions0.50.91.41.0-1.20.9-0.1-1.1-1.0-0.9-1.1-1.1
Delay discount exponential model param0.20.20.4-0.60.4-0.60.40.70.50.50.50.1
Extinction: sum of active levers before priming0.91.32.21.2-1.21.0-0.9-1.2-1.5-1.1-1.1-1.1
Active lever presses in extinction session 60.10.10.5-0.20.3-0.2-0.50.30.20.10.30.7
Bone: final force0.30.40.70.8-0.60.6-0.3-0.8-0.7-0.6-0.9-0.4
Bone: final moment0.20.30.60.8-0.50.6-0.4-0.7-0.6-0.5-0.7-0.3
Food consumed during 24 hour testing period0.50.91.4-0.90.9-1.10.61.10.90.81.20.9
Glucose0.30.50.6-0.80.7-0.70.80.70.80.70.70.4
Heart weight0.10.20.6-0.30.3-0.40.40.30.30.30.40.8
Delay discount hyperbolic model param0.30.40.8-0.80.5-0.80.50.90.70.70.70.3
Intermittent access intake day 1-15 change0.20.81.1-0.90.9-1.00.21.00.90.91.11.0
Intermittent access intake escalation0.00.30.5-0.40.5-0.50.20.60.50.60.70.5
Intermittent access intake escalation 20.30.50.9-0.60.6-0.50.40.60.90.80.70.9
Intermitt. access day 1 inactive lever presses0.11.11.81.1-1.01.1-1.3-1.1-0.7-0.9-1.2-0.4
Intermitt. access day 15 inactive lever presses0.00.00.1-0.10.1-0.10.30.00.30.20.00.2
Intermitt. access escalation Index0.82.54.01.5-1.41.4-2.0-1.4-2.0-1.7-1.4-1.2
Intermittent access day 1 total infusions0.00.10.7-0.00.0-0.0-0.8-0.00.20.2-0.00.4
Intermittent access day 15 total infusions0.00.10.3-0.20.2-0.3-0.60.20.30.30.30.3
Intermittent access terminal intake (last 3 days)0.10.21.4-0.00.1-0.0-1.2-0.00.30.20.10.3
Intermittent access total infusions0.20.31.90.2-0.20.2-1.4-0.30.0-0.1-0.20.3
Intermittent access day 1 locomotion0.10.31.2-0.20.3-0.2-1.10.20.40.40.20.8
Intermittent access day 15 total locomotion0.62.44.1-1.41.5-1.60.71.61.61.51.62.0
Intermittent access total locomotion0.70.81.9-0.60.7-0.6-0.60.61.31.10.71.4
Intermittent access standard deviation0.31.33.1-1.11.1-1.00.91.01.21.11.01.8
Left kidney weight0.00.40.80.5-0.70.90.6-0.4-0.6-0.7-0.5-0.6
Right kidney weight0.21.11.71.0-1.01.20.3-1.0-1.3-1.3-1.0-1.1
Cocaine induced anxiety0.10.30.6-0.30.6-0.6-0.20.60.80.60.6-0.0
Post-drug Anxiety0.50.50.9-0.60.9-0.9-0.10.90.80.50.90.4
Baseline Anxiety0.10.10.50.1-0.10.10.6-0.1-0.7-0.5-0.2-0.2
Tail length0.31.42.5-1.31.2-1.01.11.60.90.91.50.7
Length with tail0.10.51.2-0.70.6-0.41.11.00.40.40.80.0
Length without tail0.00.00.10.1-0.10.10.40.3-0.00.00.2-0.3
Times rat made contact with spout0.80.91.1-0.91.0-1.00.61.01.01.01.00.8
Lifetime Intake0.20.31.90.00.0-0.0-1.4-0.10.40.30.00.7
Liver weight, left0.10.10.40.5-0.30.4-0.7-0.10.0-0.1-0.1-0.2
Liver weight, right0.00.10.40.0-0.10.20.6-0.00.0-0.1-0.20.2
Locomotor activity0.10.10.4-0.30.1-0.20.40.10.60.20.00.6
Locomotor testing distance0.30.71.4-0.90.6-0.70.50.71.20.90.61.0
Locomotor testing rearing0.20.61.3-0.80.5-0.50.90.51.00.80.51.1
Locomotion in novel chamber1.52.02.81.6-1.71.5-1.4-1.6-0.9-1.2-1.5-1.1
Locomotion in novel chamber post-restriction0.20.72.40.6-0.80.6-1.5-0.90.1-0.2-0.80.8
Fecal boli incidents, locomotor time 11.43.64.7-2.01.8-1.91.82.21.71.81.91.8
Change in fecal boli incidents, locomotor task0.60.71.00.9-1.00.7-0.6-1.0-0.7-0.6-0.9-1.0
Time >=10cm from walls, locomotor time 10.81.01.6-1.00.8-1.10.71.21.31.11.20.4
Bouts of movement, locomotor time 10.10.10.3-0.40.4-0.40.40.20.10.40.20.5
Total resting periods, locomotor time 10.60.70.9-0.90.9-0.80.90.80.40.80.70.8
Rest time, locomotor task time 10.40.70.9-0.90.9-0.80.50.90.40.90.90.8
Distance moved, locomotor task time 10.41.11.91.1-1.41.2-1.1-1.1-0.4-1.1-1.0-0.7
Vertical activity count, locomotor time 10.53.24.51.9-2.01.9-1.6-2.1-1.0-1.7-2.1-1.5
Time >=10cm from walls, locomotor time 20.10.30.5-0.60.7-0.50.20.40.40.60.60.7
Bouts of movement, locomotor time 20.72.43.41.6-1.51.5-1.8-1.7-1.6-1.3-1.8-1.2
Total resting periods, locomotor time 20.83.24.21.9-1.71.7-1.9-1.9-1.9-1.6-2.0-1.4
Rest time, locomotor task time 20.10.10.2-0.30.3-0.40.10.4-0.20.20.4-0.1
Distance moved, locomotor task time 20.10.10.30.2-0.20.30.2-0.3-0.2-0.5-0.0-0.0
Vertical activity count, locomotor time 20.20.51.30.8-0.50.9-0.7-1.1-0.2-0.6-0.9-0.3
Light reinforcement 10.00.20.50.2-0.50.1-0.4-0.70.2-0.1-0.70.2
Light reinforcement 20.00.10.2-0.1-0.1-0.20.5-0.30.00.0-0.2-0.1
Bone: marrow area0.10.30.80.7-0.50.5-0.9-0.5-0.4-0.3-0.4-0.5
Bone: maximum diameter0.40.81.61.0-0.90.8-1.3-0.9-0.7-0.7-0.8-0.8
Bone: maximum force0.71.51.81.3-1.21.2-0.9-1.3-1.3-1.2-1.3-1.1
Bone: maximum moment0.61.21.51.2-1.11.1-0.8-1.1-1.1-1.1-1.1-1.0
Mean time between licks in bursts0.31.72.3-1.41.4-1.30.91.21.51.51.11.2
Mean num. licks in bursts0.51.21.5-1.01.1-1.01.21.21.11.01.21.2
Cd content in liver0.40.50.9-0.70.7-0.70.20.90.80.60.90.4
Co content in liver0.10.10.40.4-0.60.3-0.5-0.3-0.2-0.2-0.2-0.3
Cu content in liver0.40.53.60.60.1-0.0-1.9-0.50.0-0.0-0.50.2
Fe content in liver0.10.10.4-0.30.2-0.2-0.10.40.30.30.40.7
K content in liver0.00.00.20.20.20.1-0.5-0.2-0.10.0-0.1-0.2
Mg content in liver0.30.30.5-0.50.7-0.6-0.20.60.60.70.50.5
Mn content in liver0.00.00.10.1-0.30.30.0-0.1-0.2-0.2-0.1-0.3
Na content in liver0.10.10.40.10.2-0.2-0.6-0.00.20.3-0.00.2
Rb content in liver0.50.60.8-0.50.7-0.6-0.90.90.70.70.80.8
Se content in liver0.70.81.1-0.90.8-1.00.70.90.80.80.91.0
Sr content in liver0.30.30.9-0.50.5-0.50.90.30.40.40.30.4
Zn content in liver1.01.11.8-1.01.3-1.30.60.91.21.10.90.9
Bone: minimum diameter0.71.31.81.3-1.21.2-1.1-1.1-1.2-1.0-1.1-1.1
Time in familiar zone, hab. session 10.40.51.1-0.60.6-0.61.00.70.60.60.70.5
Time in novel zone, hab. session 11.92.13.11.4-1.31.4-1.8-1.4-1.4-1.4-1.4-1.4
Total zone transitions, hab. session 10.60.81.20.8-0.80.8-0.6-1.0-0.8-0.9-1.1-1.1
Total locomotion distance, hab. session 10.20.30.7-0.60.6-0.50.90.40.60.40.30.1
Locomotion velocity, hab. session 10.30.41.1-0.70.7-0.61.00.50.70.50.50.3
Time in familiar zone, hab. session 20.20.20.3-0.30.4-0.50.20.40.50.50.40.4
Time in novel zone, hab. session 20.60.60.90.7-0.81.0-0.7-0.6-0.9-0.9-0.7-0.8
Total zone transitions, hab. session 20.10.20.4-0.40.5-0.50.60.20.50.50.10.3
Total locomotion distance, hab. session 20.30.41.6-0.60.6-0.51.30.50.60.40.40.2
Locomotion velocity, hab. session 20.50.72.3-0.80.8-0.81.50.60.80.60.50.5
Novel to familiar place preference ratio0.81.01.51.0-1.01.2-0.6-0.9-1.1-1.2-0.9-1.2
Novelty place preference0.50.71.10.8-0.80.9-0.5-0.6-0.9-1.0-0.6-1.0
Time in novel zone, NPP test0.70.81.30.9-0.91.0-0.6-0.7-1.0-1.1-0.7-1.1
Total zone transitions, NPP test0.30.50.8-0.80.8-0.80.90.50.80.80.30.4
Total locomotion distance, NPP test1.31.94.4-1.51.4-1.32.11.11.41.21.01.1
Locomotion velocity, NPP test1.62.35.3-1.61.5-1.52.31.21.51.41.11.3
Intraocular pressure0.81.42.1-1.20.7-1.3-0.21.31.41.31.21.4
Delta distance traveled before/after self-admin5.15.67.1-2.32.5-2.51.62.42.52.72.42.4
Delta ambulatory time before/after self-admin2.95.06.1-2.12.3-2.21.62.32.42.52.32.3
Parametrial fat weight1.33.14.7-1.82.2-1.90.51.81.91.81.71.7
Pavlov. Cond. lever latency1.51.94.0-1.41.3-1.22.01.51.21.21.41.1
Pavlov. Cond. magazine entry latency2.63.34.51.9-1.71.7-2.1-1.9-1.7-1.7-1.9-1.7
Pavlov. Cond. change in total contacts3.63.95.72.0-1.81.8-2.4-2.1-1.8-1.8-2.1-1.8
Pavlov. Cond. index score4.35.47.92.4-2.22.2-2.8-2.5-2.1-2.2-2.5-2.0
Pavlov. Cond. latency score3.95.08.22.3-2.12.1-2.9-2.3-2.0-2.1-2.3-1.9
Pavlov. Cond. lever contacts1.82.14.21.4-1.31.3-2.1-1.6-1.2-1.2-1.6-1.2
Pavlov. Cond. magazine entry number1.92.43.6-1.61.4-1.41.91.61.31.41.61.4
Pavlov. Cond. intertrial magazine entries1.92.32.8-1.61.3-1.41.41.71.51.51.71.4
Pavlov. Cond. lever-magazine prob. diff.4.25.27.82.3-2.12.1-2.8-2.5-2.1-2.1-2.5-2.0
Pavlov. Cond. response bias1.21.52.51.2-1.11.1-1.6-1.3-1.0-1.0-1.3-1.1
Pavlov. Cond. lever latency1.21.72.41.4-1.51.5-1.0-1.2-1.2-1.4-1.1-1.3
Pavlov. Cond. magazine entry latency2.13.04.4-1.81.6-1.72.11.61.71.81.41.7
Pavlov. Cond. change in total contacts0.51.11.51.0-0.90.8-1.1-1.0-1.2-1.0-1.2-1.1
Pavlov. Cond. index score1.21.82.4-1.51.4-1.61.41.31.21.41.11.3
Pavlov. Cond. latency score1.01.72.2-1.41.3-1.51.41.21.21.31.01.2
Pavlov. Cond. lever contacts1.82.63.4-1.71.8-1.91.41.71.51.61.51.5
Pavlov. Cond. magazine entry number0.70.81.11.0-0.91.0-1.1-0.8-0.9-1.0-0.7-0.9
Pavlov. Cond. intertrial magazine entries0.71.62.8-1.31.1-1.20.91.51.11.11.71.1
Pavlov. Cond. lever-magazine prob. diff.0.81.21.7-1.21.1-1.31.21.01.01.10.81.0
Pavlov. Cond. response bias1.62.22.9-1.61.6-1.71.31.51.41.61.31.5
Time in closed arm before self-admin1.52.74.01.5-1.71.6-0.6-1.6-2.0-2.0-1.5-1.9
Time in closed arm after self-admin3.03.45.31.9-2.02.0-2.3-1.9-1.5-1.5-1.8-1.5
Time in open arm before self-admin0.60.82.41.0-0.70.9-1.5-0.7-0.6-0.6-0.8-0.7
Time in open arm after self-admin0.91.01.5-1.01.1-1.01.21.01.01.01.00.5
Bone: periosteal estimation0.51.11.61.3-1.01.0-1.2-1.1-0.9-0.8-1.1-0.9
Bone: periosteal perimeter1.32.63.31.8-1.71.6-1.5-1.5-1.6-1.5-1.5-1.6
Bone: post-yield work0.30.50.70.8-0.80.6-0.7-0.9-0.5-0.5-0.8-0.5
Progressive ratio test 1 active lever presses0.30.61.3-0.80.8-0.8-0.60.80.50.70.81.2
Progressive ratio test 1 breakpoint0.50.81.6-0.91.0-1.0-0.50.90.70.80.91.3
Progressive ratio test 1 inactive lever presses0.30.81.50.8-0.81.0-1.2-1.0-0.6-0.6-1.0-0.1
Progressive ratio test 2 active lever presses0.20.32.60.3-0.10.1-1.6-0.1-0.3-0.1-0.00.3
Progressive ratio test 2 breakpoint0.30.43.00.5-0.20.3-1.7-0.3-0.5-0.4-0.20.1
Progressive ratio test 2 inactive lever presses0.10.20.7-0.10.3-0.2-0.80.20.30.20.20.8
Incentive Sensitization - Responses0.30.71.90.9-0.60.7-1.4-0.7-0.9-0.7-0.6-0.8
Incentive Sensitization - Breakpoint0.51.02.41.1-0.80.9-1.5-0.9-1.1-0.9-0.8-0.9
Sum of active levers in priming session hrs 5-60.40.40.80.5-0.60.5-0.6-0.6-0.9-0.6-0.6-0.2
Progressive ratio0.00.00.10.0-0.30.2-0.4-0.10.10.10.10.3
Food seeking constrained by brief footshock0.30.31.90.10.10.2-1.4-0.40.1-0.0-0.11.0
Seeking ratio, punishment vs. effort0.00.00.20.00.3-0.0-0.4-0.10.0-0.0-0.10.2
Retroperitoneal fat weight2.812.515.1-3.73.7-3.52.63.93.43.43.83.6
Reaction time number correct0.51.72.6-1.31.4-1.61.01.41.41.31.50.4
Reaction time mean minus median0.10.30.80.4-0.90.6-0.3-0.6-0.6-0.8-0.50.3
Reaction time mean minus median AUC0.10.60.90.6-1.00.8-0.8-0.8-0.8-0.9-0.70.1
Reaction time num false alarms0.30.40.8-0.70.5-0.60.90.70.80.50.70.1
Reaction time num false alarms AUC0.10.10.5-0.40.2-0.30.70.20.60.30.3-0.1
Reaction time trials correct on left0.51.72.6-1.31.4-1.61.01.41.41.31.50.4
Reaction time trials on left0.51.82.7-1.31.4-1.61.11.41.41.31.50.5
Reaction time mean0.20.40.80.6-0.90.9-0.5-0.6-0.6-0.8-0.50.1
Reaction time mean AUC0.20.40.80.6-0.90.9-0.5-0.6-0.7-0.8-0.5-0.0
Median of all reaction times0.10.20.50.5-0.60.7-0.3-0.4-0.4-0.5-0.30.0
Reaction time omissions0.20.31.7-0.40.2-0.21.30.10.40.30.20.8
Reaction time false alarm rate0.30.40.60.5-0.70.7-0.3-0.7-0.5-0.6-0.7-0.6
Reaction time premature initiation rate0.91.32.1-1.21.2-1.10.41.31.11.11.21.4
Reaction time premature initiations1.03.03.7-1.81.8-1.81.01.91.71.71.91.6
Std. dev. reaction times0.20.71.30.7-1.10.9-0.5-0.9-0.8-1.0-0.80.1
Reaction time trials completed0.51.82.7-1.31.4-1.61.11.41.41.31.50.5
Reaction time trials AUC0.41.42.1-1.11.3-1.50.91.31.21.21.40.3
Run reversals in cocaine runway, females0.10.10.2-0.10.30.00.50.20.2-0.10.3-0.0
Run reversals in cocaine runway, males1.92.03.01.3-1.41.7-0.3-1.4-1.6-1.6-1.4-1.5
Latency to leave start box in cocaine runway0.10.10.40.4-0.40.2-0.7-0.2-0.3-0.3-0.2-0.4
Latency to leave start box in cocaine runway, F0.20.20.40.4-0.40.4-0.6-0.3-0.5-0.4-0.4-0.4
Latency to leave start box in cocaine runway, M0.10.10.20.3-0.3-0.1-0.5-0.2-0.1-0.1-0.1-0.3
Std. dev. time between licks in bursts1.12.12.9-1.51.7-1.51.21.41.41.41.41.3
Total sessions with >9 infusions0.30.42.10.4-0.40.4-1.5-0.4-0.2-0.3-0.40.4
Short access day 1 total inactive lever presses0.10.10.6-0.10.3-0.1-0.50.10.1-0.20.00.8
Short access day 10 total inactive lever presses0.00.20.30.5-0.40.5-0.6-0.5-0.2-0.4-0.5-0.2
Short access day 1 total infusions0.10.20.9-0.10.2-0.2-0.80.10.20.20.10.9
Short access day 10 total infusions0.20.31.60.3-0.40.3-1.3-0.3-0.2-0.2-0.30.2
Short access total infusions0.30.41.4-0.20.2-0.2-1.10.20.50.40.21.2
Short access day 1 locomotion0.10.20.50.3-0.30.3-0.7-0.4-0.3-0.3-0.40.3
Short access day 10 total locomotion0.00.10.30.3-0.30.4-0.6-0.3-0.2-0.3-0.30.2
Short access total locomotion0.20.31.10.4-0.40.4-1.1-0.5-0.4-0.4-0.50.5
One hour access (0.3 mA shock)1.11.33.81.2-1.31.1-1.9-1.1-0.6-0.7-1.1-0.3
Compulsive drug intake0.71.03.01.1-1.10.9-1.7-0.9-0.5-0.6-1.0-0.6
One hour access (shock baseline)0.10.31.00.6-0.60.5-1.0-0.6-0.4-0.5-0.6-0.1
Social response proportion1.11.42.7-1.21.2-1.11.21.01.31.10.91.7
Social responses0.20.21.1-0.40.4-0.21.00.10.60.3-0.00.6
Social time0.81.23.2-1.00.9-0.91.80.61.31.10.61.2
Soleus weight0.00.00.1-0.00.3-0.10.20.10.10.10.1-0.0
Bone: stiffness2.54.55.52.3-1.92.0-1.8-2.3-2.2-2.2-2.3-2.0
Tibialis anterior weight10.134.841.36.0-6.26.2-5.0-5.3-6.3-6.3-5.2-6.4
Time to tail flick, vehicle, before self-admin0.40.50.80.6-0.90.9-0.4-0.8-0.5-0.7-0.80.4
Time to tail flick, vehicle, after self-admin0.20.41.10.6-0.80.30.2-0.7-0.2-0.2-0.7-1.0
Time to tail flick, test, before self-admin0.60.71.10.6-0.81.00.2-0.9-0.9-1.0-0.9-0.7
Time to tail flick, test, after self-admin0.90.91.81.0-1.31.10.1-1.1-0.9-1.0-1.1-0.5
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.30.4-0.80.40.40.50.60.4-0.3
Delta time to tail flick, test, before/after SA0.00.00.20.3-0.40.10.2-0.1-0.1-0.0-0.20.1
Tibia length0.00.00.10.1-0.30.1-0.30.30.10.10.20.1
Ambulatory time before self-admin0.00.10.8-0.30.2-0.1-0.20.10.30.40.20.9
Ambulatory time after self-admin1.93.05.2-1.51.8-1.40.51.72.02.11.72.3
Bone: tissue strength1.11.21.71.1-1.21.1-1.3-1.0-1.1-1.0-1.0-0.9
Total heroin consumption0.10.10.40.10.10.1-0.60.1-0.4-0.30.10.7
Bone: trabecular number0.10.20.4-0.30.4-0.40.40.20.60.60.10.5
Bone: trabecular spacing0.30.51.80.5-0.70.6-1.3-0.3-0.6-0.7-0.3-0.5
Bone: trabecular thickness0.20.30.50.5-0.40.50.0-0.5-0.6-0.5-0.6-0.7
Bone: trabecular tissue density2.34.05.31.9-1.91.9-1.6-2.0-2.1-2.0-2.0-2.3
Water consumed over 24 hours0.50.91.2-1.00.8-1.00.61.10.90.91.10.9
Number of responses in last shaping day0.40.63.3-0.50.4-0.41.80.50.40.30.5-0.7