Hub : Traits : Tibialis anterior weight : ← : →

chr11:45,605,638-48,744,257

Trait: Tibialis anterior weight

Best TWAS P = 3.70e-10 · Best GWAS P= 6.54e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dyrk1a	alternative TSS	NM_012791.3	0.05	1966	0.04	6.6e-05	-5.98	2.22e-09	0.56	FALSE
Adipose	Dyrk1a	alternative TSS	XM_039088032.2	0.03	1	0.02	1.7e-03	-5.81	6.10e-09	0.04	FALSE
Adipose	Dyrk1a	alternative TSS	XM_063270304.1	0.04	1966	0.04	2.8e-05	6.01	1.85e-09	0.58	FALSE
Adipose	Dyrk1a	alternative TSS	NM_012791.3	0.05	1966	0.04	6.1e-05	-5.98	2.23e-09	0.56	FALSE
Adipose	Dyrk1a	alternative TSS	XM_063270304.1	0.04	1	0.03	1.6e-04	-5.97	2.35e-09	0.2	FALSE
Adipose	Kcnj15	alternative TSS	XM_006248135.4	0.04	1	0.02	3.5e-03	5.71	1.16e-08	0.03	TRUE
Adipose	Ttc3	alternative TSS	XM_039088464.2	0.08	1	0.07	1.9e-08	5.96	2.45e-09	0.64	FALSE
Adipose	Ttc3	alternative TSS	XM_039088466.2	0.02	1	0.02	1.8e-03	-5.87	4.37e-09	0.04	FALSE
Adipose	Ttc3	alternative TSS	XM_039088464.2	0.09	1	0.08	6.5e-09	5.96	2.45e-09	0.64	FALSE
Adipose	Sim2	gene expression	Sim2	0.03	1	0.01	1.6e-02	5.87	4.40e-09	0.04	FALSE
Adipose	Ttc3	gene expression	Ttc3	0.31	2025	0.36	4.7e-42	5.84	5.07e-09	0.59	FALSE
Adipose	Ttc3	isoform ratio	XM_039088464.2	0.09	1	0.05	1.1e-06	5.96	2.45e-09	0.63	FALSE
Adipose	Ttc3	intron excision ratio	chr11_47172097_47173097	0.02	1	0.02	2.1e-03	-5.87	4.37e-09	0.03	FALSE
Adipose	Vps26c	intron excision ratio	chr11_47296165_47296663	0.21	11	0.26	2.3e-28	5.82	6.05e-09	0	TRUE
Adipose	Cbr1	mRNA stability	Cbr1	0.18	2085	0.13	3.2e-14	5.72	1.05e-08	0.71	FALSE
BLA	Dop1b	gene expression	Dop1b	0.11	1	0.06	4.7e-04	-5.28	1.32e-07	0.04	TRUE
BLA	Setd4	gene expression	Setd4	0.41	13	0.3	1.4e-16	5.86	4.54e-09	0.68	FALSE
BLA	Sim2	gene expression	Sim2	0.06	1	0.05	1.9e-03	5.93	3.09e-09	0.06	FALSE
BLA	Setd4	isoform ratio	XM_063270278.1	0.04	2077	0.04	2.4e-03	5.29	1.19e-07	0.34	FALSE
BLA	Cbr1	intron excision ratio	chr11_46363568_46364473	0.05	2085	0.03	1.1e-02	5.42	6.00e-08	0.4	FALSE
BLA	Cbr1l1	intron excision ratio	chr11_46363568_46364473	0.05	2088	0.03	1.1e-02	5.41	6.38e-08	0.39	FALSE
BLA	Cbr1l2	intron excision ratio	chr11_46363568_46364473	0.05	1	0.04	4.3e-03	-5.54	3.09e-08	0.04	FALSE
BLA	Setd4	intron excision ratio	chr11_46331706_46339270	0.1	1	0.05	1.1e-03	5.88	3.99e-09	0.14	FALSE
BLA	Ttc3	intron excision ratio	chr11_47191604_47204173	0.05	1	0.03	7.6e-03	-5.84	5.30e-09	0.04	FALSE
BLA	Kcnj6	mRNA stability	Kcnj6	0.09	2530	0.03	6.8e-03	5.29	1.25e-07	0.42	FALSE
BLA	Vps26c	mRNA stability	Vps26c	0.22	1932	0.21	3.1e-11	-5.74	9.55e-09	0.6	FALSE
Brain	Cldn14	alternative TSS	XM_039088410.2	0.03	1737	0.01	1.3e-02	5.86	4.50e-09	0.58	FALSE
Brain	Cbr1l1	gene expression	Cbr1l1	0.67	197	0.64	6.9e-77	-5.49	3.91e-08	0.73	FALSE
Brain	Dop1b	gene expression	Dop1b	0.15	26	0.1	3.4e-09	5.78	7.54e-09	0.63	FALSE
Brain	LOC134481059	gene expression	LOC134481059	0.08	1	0.08	4.2e-08	5.93	3.09e-09	0.71	FALSE
Brain	RGD1562683	gene expression	RGD1562683	0.07	2003	0.07	6.8e-07	-5.71	1.12e-08	0.68	FALSE
Brain	Setd4	gene expression	Setd4	0.43	195	0.49	7.8e-52	-6.12	9.61e-10	0.7	FALSE
Brain	Kcnj6	isoform ratio	NM_001393803.1	0.55	16	0.4	2.5e-40	-5.34	9.08e-08	0.69	FALSE
Brain	Kcnj6	isoform ratio	NM_013192.3	0.5	8	0.39	5.3e-38	5.42	6.02e-08	0.69	TRUE
Brain	Setd4	isoform ratio	NM_001113747.1	0.09	2077	0.08	9.4e-08	-5.63	1.79e-08	0.66	FALSE
Brain	Setd4	isoform ratio	XM_063270278.1	0.21	1	0.22	1.5e-20	-5.93	3.09e-09	0.8	FALSE
Brain	Cbr1	intron excision ratio	chr11_46346786_46347257	0.05	11	0.07	3.0e-07	-5.39	7.18e-08	0.45	FALSE
Brain	Cbr1l1	intron excision ratio	chr11_46346786_46347257	0.05	10	0.07	3.2e-07	-5.31	1.07e-07	0.45	FALSE
Brain	Cbr1l2	intron excision ratio	chr11_46346786_46347257	0.05	6	0.07	3.4e-07	5.28	1.26e-07	0.44	FALSE
Brain	Kcnj6	intron excision ratio	chr11_47719990_47778156	0.05	21	0.04	5.5e-05	5.42	5.99e-08	0.52	FALSE
Brain	Kcnj6	intron excision ratio	chr11_47746001_47778156	0.04	1	0.03	7.0e-04	5.72	1.05e-08	0.05	FALSE
Brain	Setd4	intron excision ratio	chr11_46331706_46333234	0.07	2077	0.06	7.1e-06	5.43	5.54e-08	0.68	FALSE
Brain	Setd4	intron excision ratio	chr11_46333322_46336544	0.07	1	0.07	4.2e-07	-5.74	9.70e-09	0.57	FALSE
Brain	Ttc3	intron excision ratio	chr11_47191604_47204173	0.15	2025	0.18	3.5e-16	5.53	3.28e-08	0.62	FALSE
Brain	Cbr1l1	mRNA stability	Cbr1l1	0.07	4	0.06	2.0e-06	6.27	3.70e-10	0.64	TRUE
Brain	Setd4	mRNA stability	Setd4	0.07	6	0.04	9.4e-05	-5.94	2.82e-09	0.69	FALSE
Brain	Vps26c	mRNA stability	Vps26c	0.2	48	0.23	4.6e-21	5.48	4.29e-08	0.48	FALSE
Eye	Morc3	isoform ratio	XM_063270584.1	0.42	1	0.07	2.9e-02	-5.9	3.53e-09	0.06	FALSE
Eye	Vps26c	mRNA stability	Vps26c	0.53	1	0.27	4.2e-05	6.17	6.95e-10	0.08	FALSE
IC	Cbr1l1	gene expression	Cbr1l1	0.49	18	0.46	3.9e-21	5.66	1.51e-08	0.66	FALSE
IC	Setd4	gene expression	Setd4	0.31	2077	0.25	7.5e-11	5.3	1.16e-07	0.67	TRUE
IC	Setd4	isoform ratio	XM_063270278.1	0.11	1	0.07	5.9e-04	-5.9	3.69e-09	0.1	FALSE
IC	Cbr1	intron excision ratio	chr11_46362976_46363461	0.1	2085	0.03	1.8e-02	5.47	4.59e-08	0.4	FALSE
IC	Cbr1l1	intron excision ratio	chr11_46362976_46363461	0.1	2088	0.03	1.9e-02	5.46	4.73e-08	0.39	FALSE
IC	Cbr1l2	intron excision ratio	chr11_46362976_46363461	0.09	2110	0.03	2.0e-02	5.47	4.57e-08	0.39	FALSE
IC	Ttc3	intron excision ratio	chr11_47191604_47204173	0.1	2025	0.08	4.0e-04	5.73	9.81e-09	0.59	FALSE
IC	Vps26c	mRNA stability	Vps26c	0.35	1932	0.16	3.1e-07	-5.89	3.76e-09	0.61	FALSE
IL	Cbr1l1	gene expression	Cbr1l1	0.53	14	0.3	7.4e-08	5.89	3.93e-09	0.68	FALSE
IL	Setd4	gene expression	Setd4	0.5	1	0.36	1.6e-09	-6.05	1.49e-09	0.86	FALSE
IL	Setd4	intron excision ratio	chr11_46331706_46333234	0.14	1	0.06	1.6e-02	-5.78	7.47e-09	0.05	FALSE
IL	Setd4	intron excision ratio	chr11_46331706_46339270	0.19	2077	0.13	5.8e-04	-5.76	8.55e-09	0.6	FALSE
IL	Vps26c	mRNA stability	Vps26c	0.2	1	0.13	4.1e-04	6.08	1.18e-09	0.07	FALSE
LHb	Cbr1l1	gene expression	Cbr1l1	0.62	10	0.59	4.3e-17	5.42	5.94e-08	0.52	FALSE
LHb	Cldn14	gene expression	Cldn14	0.18	4	0.13	5.7e-04	-5.55	2.91e-08	0.52	TRUE
LHb	Setd4	gene expression	Setd4	0.29	2077	0.29	1.4e-07	5.49	3.97e-08	0.67	FALSE
LHb	Setd4	isoform ratio	XM_063270278.1	0.2	4	0.12	8.4e-04	5.93	3.09e-09	0.61	TRUE
LHb	Vps26c	mRNA stability	Vps26c	0.37	64	0.29	1.1e-07	6.04	1.57e-09	0.6	TRUE
Liver	Cldn14	alternative TSS	NM_001013429.1	0.17	28	0.16	3.2e-17	5.32	1.04e-07	0.65	FALSE
Liver	Cldn14	alternative TSS	XM_006248059.4	0.22	1737	0.21	2.5e-23	5.54	2.95e-08	0.65	FALSE
Liver	Cldn14	gene expression	Cldn14	0.05	1	0.04	1.1e-05	-5.52	3.35e-08	0.17	FALSE
Liver	Dop1b	gene expression	Dop1b	0.09	2023	0.07	6.0e-08	5.59	2.32e-08	0.64	FALSE
Liver	Setd4	gene expression	Setd4	0.32	89	0.3	2.9e-34	-5.83	5.61e-09	0.69	FALSE
Liver	Cldn14	isoform ratio	NM_001013429.1	0.18	20	0.17	4.2e-18	-5.59	2.24e-08	0.65	FALSE
Liver	Cldn14	isoform ratio	XM_006248059.4	0.23	1737	0.22	2.6e-24	5.47	4.38e-08	0.64	FALSE
Liver	Morc3	isoform ratio	XM_039088415.2	0.02	1785	0.01	2.7e-02	-5.47	4.44e-08	0.46	FALSE
Liver	Cldn14	intron excision ratio	chr11_46702955_46711339	0.06	1	0.05	7.6e-06	6.05	1.49e-09	0.67	FALSE
Liver	Cldn14	mRNA stability	Cldn14	0.5	34	0.46	1.7e-56	5.77	8.14e-09	0.66	FALSE
Liver	Dyrk1a	mRNA stability	Dyrk1a	0.02	1	0.01	3.5e-02	6.08	1.18e-09	0.04	FALSE
Liver	Hlcs	mRNA stability	Hlcs	0.09	24	0.1	8.6e-11	5.43	5.65e-08	0.37	FALSE
NAcc	Dyrk1a	alternative TSS	NM_012791.3	0.02	1	0.01	1.8e-03	5.94	2.88e-09	0.06	FALSE
NAcc	Dyrk1a	alternative TSS	NM_012791.3	0.02	1	0.02	8.2e-04	5.94	2.88e-09	0.09	FALSE
NAcc	Cbr1l1	gene expression	Cbr1l1	0.52	187	0.58	6.1e-110	-5.54	3.06e-08	0.66	FALSE
NAcc	Ripply3	gene expression	Ripply3	0.06	1	0.06	2.6e-09	5.93	2.98e-09	0.64	FALSE
NAcc	Setd4	gene expression	Setd4	0.38	35	0.33	1.6e-51	5.63	1.82e-08	0.67	FALSE
NAcc	Setd4	isoform ratio	XM_063270278.1	0.09	1	0.13	9.6e-19	-5.85	4.88e-09	0.73	FALSE
NAcc	Cbr1	intron excision ratio	chr11_46379646_46380552	0.09	1	0.09	4.7e-13	5.87	4.42e-09	0.74	FALSE
NAcc	Cbr1l1	intron excision ratio	chr11_46379646_46380552	0.09	1	0.09	4.7e-13	5.87	4.42e-09	0.74	FALSE
NAcc	Cbr1l2	intron excision ratio	chr11_46379646_46380552	0.09	1	0.09	4.7e-13	5.87	4.42e-09	0.73	FALSE
NAcc	Setd4	intron excision ratio	chr11_46331706_46333234	0.04	1	0.05	1.2e-07	-5.78	7.44e-09	0.64	FALSE
NAcc	Setd4	intron excision ratio	chr11_46331706_46339270	0.03	2077	0.02	6.5e-04	-5.41	6.33e-08	0.65	FALSE
NAcc	Setd4	intron excision ratio	chr11_46333322_46336544	0.05	1	0.05	1.6e-08	-5.77	7.75e-09	0.63	FALSE
NAcc	Setd4	intron excision ratio	chr11_46336581_46339270	0.03	2077	0.02	1.2e-04	5.56	2.69e-08	0.67	FALSE
NAcc	Ttc3	intron excision ratio	chr11_47191604_47204173	0.03	16	0.03	5.7e-06	5.83	5.45e-09	0.54	TRUE
NAcc	Vps26c	mRNA stability	Vps26c	0.12	1932	0.15	2.5e-21	-5.67	1.46e-08	0.38	FALSE
OFC	Dop1b	gene expression	Dop1b	0.15	1	0.14	4.0e-04	-5.78	7.47e-09	0.06	FALSE
OFC	Setd4	gene expression	Setd4	0.37	1	0.32	2.1e-08	-5.93	3.09e-09	0.61	FALSE
OFC	Kcnj6	intron excision ratio	chr11_47719990_47778156	0.14	2530	0.07	7.5e-03	5.7	1.19e-08	0.39	FALSE
OFC	Kcnj6	intron excision ratio	chr11_47746001_47778156	0.15	2530	0.11	1.2e-03	-5.92	3.21e-09	0.47	FALSE
PL	Hlcs	gene expression	Hlcs	0.07	1942	0.07	5.2e-08	-5.79	7.06e-09	0.59	FALSE
PL	Kcnj6	gene expression	Kcnj6	0.03	1	0.03	7.5e-04	-6.08	1.18e-09	0.17	FALSE
PL	Setd4	gene expression	Setd4	0.28	2077	0.33	3.8e-37	5.6	2.16e-08	0.7	FALSE
PL	Morc3	isoform ratio	XM_063270585.1	0.03	40	0.03	2.8e-04	-5.48	4.23e-08	0.33	TRUE
PL	Setd4	isoform ratio	XM_063270278.1	0.15	16	0.19	2.1e-20	5.86	4.49e-09	0.71	FALSE
PL	Cbr1	intron excision ratio	chr11_46363568_46364473	0.04	14	0.05	5.6e-06	5.47	4.58e-08	0.4	FALSE
PL	Cbr1	intron excision ratio	chr11_46379646_46380552	0.03	2085	0.02	2.7e-03	-5.51	3.50e-08	0.64	FALSE
PL	Cbr1l1	intron excision ratio	chr11_46363568_46364473	0.04	12	0.05	5.3e-06	5.47	4.50e-08	0.42	FALSE
PL	Cbr1l1	intron excision ratio	chr11_46379646_46380552	0.03	2088	0.02	2.8e-03	-5.5	3.87e-08	0.64	FALSE
PL	Cbr1l2	intron excision ratio	chr11_46363568_46364473	0.04	14	0.05	4.9e-06	5.47	4.54e-08	0.42	FALSE
PL	Cbr1l2	intron excision ratio	chr11_46379646_46380552	0.03	1	0.02	1.2e-03	5.89	3.84e-09	0.16	FALSE
PL	Morc3	intron excision ratio	chr11_46632835_46633662	0.03	7	0.01	9.9e-03	5.64	1.67e-08	0.59	FALSE
PL	Setd4	intron excision ratio	chr11_46331706_46333234	0.03	1	0.04	2.4e-05	-5.77	7.75e-09	0.22	FALSE
PL	Setd4	intron excision ratio	chr11_46331706_46339270	0.04	34	0.03	6.7e-04	5.46	4.67e-08	0.59	FALSE
PL	Ttc3	intron excision ratio	chr11_47191604_47204173	0.11	1	0.1	5.1e-11	-5.82	5.99e-09	0.43	FALSE
PL	Ttc3	intron excision ratio	chr11_47196778_47197751	0.02	1	0.03	4.7e-04	5.78	7.51e-09	0.04	FALSE
PL	Setd4	mRNA stability	Setd4	0.04	2077	0.03	1.9e-04	-5.25	1.53e-07	0.51	FALSE
PL	Vps26c	mRNA stability	Vps26c	0.2	1	0.29	9.4e-32	5.93	3.05e-09	0.56	FALSE
pVTA	Cbr1l1	gene expression	Cbr1l1	0.56	2088	0.55	4.5e-52	5.65	1.56e-08	0.68	FALSE
pVTA	Cbr3	gene expression	Cbr3	0.08	2023	0.05	1.4e-04	-5.4	6.63e-08	0.59	FALSE
pVTA	Ripply3	gene expression	Ripply3	0.06	1939	0.04	4.6e-04	-5.48	4.20e-08	0.47	FALSE
pVTA	Setd4	gene expression	Setd4	0.19	2077	0.19	2.6e-15	5.51	3.64e-08	0.69	FALSE
pVTA	Kcnj6	isoform ratio	NM_001393803.1	0.19	1	0.14	2.4e-11	6.08	1.17e-09	0.81	FALSE
pVTA	Kcnj6	isoform ratio	NM_013192.3	0.21	17	0.15	4.5e-12	5.82	5.97e-09	0.7	FALSE
pVTA	Setd4	isoform ratio	XM_063270278.1	0.07	2077	0.06	2.1e-05	5.59	2.26e-08	0.67	FALSE
pVTA	Cbr1	intron excision ratio	chr11_46347364_46348270	0.07	1	0.04	1.4e-04	5.82	5.89e-09	0.21	FALSE
pVTA	Cbr1	intron excision ratio	chr11_46363568_46364473	0.25	2085	0.24	3.6e-19	5.56	2.70e-08	0.69	FALSE
pVTA	Cbr1	intron excision ratio	chr11_46379646_46380552	0.08	2085	0.06	2.0e-05	-5.56	2.71e-08	0.68	FALSE
pVTA	Cbr1l1	intron excision ratio	chr11_46347364_46348270	0.08	1	0.04	1.4e-04	5.82	5.89e-09	0.21	FALSE
pVTA	Cbr1l1	intron excision ratio	chr11_46363568_46364473	0.23	2088	0.24	4.9e-19	5.6	2.14e-08	0.68	FALSE
pVTA	Cbr1l1	intron excision ratio	chr11_46379646_46380552	0.08	2088	0.06	2.0e-05	-5.55	2.94e-08	0.67	FALSE
pVTA	Cbr1l2	intron excision ratio	chr11_46347364_46348270	0.08	1	0.04	1.4e-04	5.82	5.89e-09	0.2	FALSE
pVTA	Cbr1l2	intron excision ratio	chr11_46363568_46364473	0.23	2110	0.24	5.4e-19	5.6	2.08e-08	0.67	FALSE
pVTA	Cbr1l2	intron excision ratio	chr11_46379646_46380552	0.09	2110	0.06	2.1e-05	-5.54	3.02e-08	0.66	FALSE
pVTA	Ttc3	intron excision ratio	chr11_47191604_47204173	0.04	1	0.03	3.3e-03	-5.85	4.88e-09	0.04	FALSE
pVTA	Vps26c	mRNA stability	Vps26c	0.06	1932	0.02	1.6e-02	-5.72	1.08e-08	0.39	FALSE
RMTg	Cbr1l1	gene expression	Cbr1l1	0.46	36	0.49	8.6e-15	-5.52	3.30e-08	0.69	FALSE
RMTg	Setd4	gene expression	Setd4	0.37	48	0.28	3.7e-08	-5.56	2.64e-08	0.47	FALSE
RMTg	Setd4	intron excision ratio	chr11_46331706_46339270	0.14	1	0.13	2.6e-04	5.76	8.48e-09	0.07	FALSE