Hub : Traits : Tibialis anterior weight : ← : →

chr5:54,563,228-59,007,126

Trait: Tibialis anterior weight

Best TWAS P=5.35e-09 · Best GWAS P=2.67e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Aptx	alternative TSS	ENSRNOT00000090891	0.03	2064	0.01	2.7e-02	-5.19	2.08e-07	0.52	FALSE
Adipose	Aptx	alternative TSS	ENSRNOT00000115715	0.05	19	0.03	7.0e-04	5.1	3.46e-07	0.62	FALSE
Adipose	Dnaja1	gene expression	ENSRNOG00000007029	0.13	1	0.09	6.3e-10	5.15	2.63e-07	0.51	FALSE
Adipose	Stoml2	gene expression	ENSRNOG00000009535	0.03	13	0.01	9.5e-03	5.53	3.13e-08	0.56	FALSE
Adipose	Nol6	gene expression	ENSRNOG00000010409	0.05	1	0.03	1.7e-04	5.58	2.39e-08	0.1	FALSE
Adipose	Ubap1	gene expression	ENSRNOG00000012004	0.19	1	0.18	1.5e-19	-5.1	3.35e-07	0.1	FALSE
Adipose	Galt	gene expression	ENSRNOG00000014766	0.23	4	0.24	1.4e-26	-5.24	1.59e-07	0.66	FALSE
Adipose	Npr2	gene expression	ENSRNOG00000015991	0.04	1828	0.01	2.3e-02	-5.26	1.48e-07	0.48	FALSE
Adipose	Rgp1	gene expression	ENSRNOG00000016309	0.02	1	0.01	2.1e-02	5.31	1.08e-07	0.03	FALSE
Adipose	ENSRNOG00000022601	gene expression	ENSRNOG00000022601	0.28	18	0.22	1.5e-23	-5.32	1.05e-07	0.68	FALSE
Adipose	B4galt1	gene expression	ENSRNOG00000059461	0.06	1	0.03	1.7e-04	5.13	2.84e-07	0.06	FALSE
Adipose	ENSRNOG00000062709	gene expression	ENSRNOG00000062709	0.33	2116	0.35	1.2e-39	-5.11	3.19e-07	0.68	FALSE
Adipose	Aptx	isoform ratio	ENSRNOT00000046463	0.42	191	0.37	4.6e-43	-5.31	1.09e-07	0.75	FALSE
Adipose	Aptx	isoform ratio	ENSRNOT00000094147	0.5	178	0.41	1.7e-49	5.42	5.82e-08	0.75	FALSE
Adipose	Unc13b	isoform ratio	ENSRNOT00000078274	0.08	1658	0.07	1.6e-08	-5.33	9.75e-08	0.57	FALSE
Adipose	Aptx	intron excision ratio	chr5:55811580:55813276	0.22	473	0.17	3.4e-18	-5.17	2.30e-07	0.73	FALSE
Adipose	Aptx	intron excision ratio	chr5:55811580:55813754	0.59	251	0.41	1.8e-48	5.16	2.53e-07	0.73	FALSE
Adipose	Aptx	intron excision ratio	chr5:55813800:55815552	0.04	1	0.03	1.3e-04	5.11	3.20e-07	0.07	FALSE
Adipose	Galt	intron excision ratio	chr5:56927674:56927897	0.02	1	0.03	7.3e-04	-5.1	3.35e-07	0.03	FALSE
Adipose	Galt	intron excision ratio	chr5:56927674:56927900	0.02	1	0.02	1.2e-03	5.1	3.35e-07	0.03	FALSE
Adipose	Ddx58	mRNA stability	ENSRNOG00000006384	0.06	1	0.03	2.6e-04	-5.15	2.63e-07	0.14	FALSE
Adipose	Smu1	mRNA stability	ENSRNOG00000007671	0.06	1	0.05	7.1e-06	-5.1	3.43e-07	0.33	FALSE
Adipose	Ubap1	mRNA stability	ENSRNOG00000012004	0.06	10	0.03	3.9e-04	5.35	8.71e-08	0.62	FALSE
Adipose	Il11ra1	mRNA stability	ENSRNOG00000015068	0.03	1	0.01	4.0e-02	-5.31	1.12e-07	0.03	FALSE
Adipose	Atp8b5p	mRNA stability	ENSRNOG00000021704	0.07	1	0.06	2.6e-07	5.7	1.21e-08	0.79	FALSE
BLA	Aptx	gene expression	ENSRNOG00000006582	0.38	109	0.21	2.4e-11	5.36	8.25e-08	0.76	FALSE
BLA	Fam219a	gene expression	ENSRNOG00000039559	0.09	1288	0.06	2.9e-04	5.53	3.22e-08	0.62	FALSE
BLA	Tmem215	gene expression	ENSRNOG00000042246	0.19	1	0.15	1.3e-08	5.38	7.39e-08	0.75	FALSE
BLA	ENSRNOG00000068351	gene expression	ENSRNOG00000068351	0.06	1	0.03	1.3e-02	-5.46	4.69e-08	0.04	FALSE
BLA	Smim27	gene expression	ENSRNOG00000069822	0.06	2227	0.04	3.9e-03	-5.67	1.43e-08	0.36	FALSE
BLA	Aptx	isoform ratio	ENSRNOT00000094147	0.76	90	0.55	6.3e-35	5.2	1.98e-07	0.75	FALSE
BLA	Unc13b	isoform ratio	ENSRNOT00000078274	0.07	1	0.05	1.3e-03	-5.68	1.35e-08	0.05	FALSE
BLA	Tpm2	isoform ratio	ENSRNOT00000022801	0.12	1658	0.09	1.9e-05	5.37	7.93e-08	0.69	FALSE
BLA	Aptx	intron excision ratio	chr5:55811580:55813276	0.16	2064	0.11	2.1e-06	-5.14	2.69e-07	0.54	FALSE
BLA	Vcp	mRNA stability	ENSRNOG00000034242	0.06	1579	0.03	1.2e-02	5.48	4.22e-08	0.42	FALSE
Brain	Ddx58	alternative TSS	ENSRNOT00000060765	0.07	11	0.09	8.1e-09	-5.35	8.66e-08	0.2	FALSE
Brain	Ddx58	alternative TSS	ENSRNOT00000107881	0.07	11	0.09	9.8e-09	5.38	7.42e-08	0.22	FALSE
Brain	Unc13b	gene expression	ENSRNOG00000008237	0.04	2	0.03	8.9e-04	5.69	1.25e-08	0.6	FALSE
Brain	Nudt2	gene expression	ENSRNOG00000013110	0.08	7	0.05	2.1e-05	-5.64	1.71e-08	0.73	FALSE
Brain	Npr2	gene expression	ENSRNOG00000015991	0.08	1	0.06	6.1e-06	5.7	1.18e-08	0.69	FALSE
Brain	Ccdc107	gene expression	ENSRNOG00000017253	0.09	1	0.09	1.7e-08	-5.31	1.10e-07	0.49	FALSE
Brain	Atp8b5p	gene expression	ENSRNOG00000021704	0.14	44	0.14	9.4e-13	5.63	1.77e-08	0.72	FALSE
Brain	Ccl21	gene expression	ENSRNOG00000034290	0.05	6	0.03	1.1e-03	-5.31	1.08e-07	0.47	FALSE
Brain	Fam219a	gene expression	ENSRNOG00000039559	0.04	1	0.02	3.7e-03	5.62	1.96e-08	0.05	FALSE
Brain	Tmem215	gene expression	ENSRNOG00000042246	0.27	1	0.22	3.8e-20	5.2	2.01e-07	0.54	FALSE
Brain	Dcaf12	gene expression	ENSRNOG00000050790	0.28	1	0.15	3.6e-14	5.3	1.15e-07	0.25	FALSE
Brain	Aptx	isoform ratio	ENSRNOT00000046463	0.48	1	0.44	5.9e-44	-5.69	1.27e-08	0.95	FALSE
Brain	Aptx	isoform ratio	ENSRNOT00000094147	0.54	1	0.47	4.0e-49	5.32	1.04e-07	0.72	FALSE
Brain	Unc13b	isoform ratio	ENSRNOT00000078274	0.1	1	0.08	4.8e-08	-5.7	1.18e-08	0.78	FALSE
Brain	Aptx	intron excision ratio	chr5:55811580:55813276	0.1	1	0.07	7.8e-07	-5.27	1.34e-07	0.66	FALSE
Brain	Fam214b	intron excision ratio	chr5:57265299:57268368	0.05	1	0.04	8.0e-05	-5.61	2.06e-08	0.24	FALSE
Brain	Phf24	mRNA stability	ENSRNOG00000000129	0.38	1	0.27	3.2e-25	-5.64	1.67e-08	0.61	FALSE
Brain	Unc13b	mRNA stability	ENSRNOG00000008237	0.2	9	0.18	3.8e-16	-5.3	1.13e-07	0.61	FALSE
Brain	Fam214b	mRNA stability	ENSRNOG00000009323	0.03	1	0.03	1.5e-03	5.69	1.30e-08	0.04	FALSE
Brain	Pigo	mRNA stability	ENSRNOG00000009930	0.08	4	0.06	4.0e-06	5.1	3.34e-07	0.39	FALSE
Brain	Ccdc107	mRNA stability	ENSRNOG00000017253	0.1	1617	0.13	5.4e-12	5.23	1.73e-07	0.71	FALSE
Brain	Tesk1	mRNA stability	ENSRNOG00000053729	0.08	18	0.09	1.3e-08	5.28	1.29e-07	0.47	FALSE
Eye	Ccl19	alternative polyA	ENSRNOT00000020982	0.29	1	0.11	1.1e-02	-5.6	2.18e-08	0.06	FALSE
Eye	Ccl19	alternative polyA	ENSRNOT00000101776	0.33	1	0.12	7.1e-03	5.6	2.18e-08	0.06	FALSE
Eye	Ddx58	gene expression	ENSRNOG00000006384	0.37	1	0.23	2.3e-04	-5.2	2.01e-07	0.06	FALSE
Eye	Nudt2	gene expression	ENSRNOG00000013110	0.37	1	0.19	6.8e-04	-5.84	5.35e-09	0.07	TRUE
Eye	Tmem215	gene expression	ENSRNOG00000042246	0.27	1	0.21	3.2e-04	5.18	2.17e-07	0.06	FALSE
Eye	Gne	isoform ratio	ENSRNOT00000115719	0.62	24	0.27	4.4e-05	5.17	2.32e-07	0.42	FALSE
Eye	Aptx	intron excision ratio	chr5:55811580:55813754	0.86	158	0.24	1.5e-04	5.16	2.40e-07	0.42	FALSE
Eye	Fam214b	mRNA stability	ENSRNOG00000009323	0.33	1	0.11	1.0e-02	5.62	1.96e-08	0.06	FALSE
Eye	Ccdc107	mRNA stability	ENSRNOG00000017253	0.35	65	0.16	2.0e-03	5.55	2.82e-08	0.39	FALSE
IL	Phf24	gene expression	ENSRNOG00000000129	0.17	6	0.14	2.6e-04	5.8	6.65e-09	0.5	FALSE
IL	Ccl21	gene expression	ENSRNOG00000034290	0.31	1	0.26	5.3e-07	-5.62	1.90e-08	0.18	FALSE
IL	ENSRNOG00000068351	gene expression	ENSRNOG00000068351	0.15	1344	0.1	2.0e-03	-5.52	3.33e-08	0.5	FALSE
IL	Unc13b	isoform ratio	ENSRNOT00000078274	0.29	4	0.27	4.0e-07	-5.14	2.70e-07	0.51	FALSE
IL	Phf24	mRNA stability	ENSRNOG00000000129	0.19	9	0.12	1.1e-03	-5.58	2.36e-08	0.48	FALSE
IL	Gne	mRNA stability	ENSRNOG00000014365	0.41	6	0.35	3.3e-09	-5.2	2.00e-07	0.67	FALSE
LHb	Aco1	gene expression	ENSRNOG00000005849	0.21	2235	0.08	6.5e-03	5.28	1.31e-07	0.23	FALSE
LHb	Ddx58	gene expression	ENSRNOG00000006384	0.34	1	0.19	2.5e-05	-5.39	7.19e-08	0.09	FALSE
LHb	Tmem215	gene expression	ENSRNOG00000042246	0.18	1	0.06	1.6e-02	5.1	3.45e-07	0.05	FALSE
Liver	Aptx	alternative TSS	ENSRNOT00000046463	0.05	1	0.02	4.0e-03	5.12	3.07e-07	0.1	FALSE
Liver	Pigo	gene expression	ENSRNOG00000009930	0.1	43	0.11	1.1e-11	5.22	1.77e-07	0.05	FALSE
Liver	Ccdc107	gene expression	ENSRNOG00000017253	0.26	67	0.18	1.1e-19	-5.34	9.52e-08	0.75	FALSE
Liver	Atp8b5p	gene expression	ENSRNOG00000021704	0.42	516	0.38	7.5e-45	5.14	2.74e-07	0.71	FALSE
Liver	Ccl21	gene expression	ENSRNOG00000034290	0.09	1	0.08	4.7e-09	5.49	3.94e-08	0.39	FALSE
Liver	Dcaf12	gene expression	ENSRNOG00000050790	0.04	46	0.02	2.0e-03	5.42	5.82e-08	0.68	FALSE
Liver	ENSRNOG00000063741	gene expression	ENSRNOG00000063741	0.13	375	0.09	3.5e-10	-5.55	2.86e-08	0.78	FALSE
Liver	Smim27	gene expression	ENSRNOG00000069822	0.03	1	0.03	3.1e-04	-5.1	3.37e-07	0.04	FALSE
Liver	Ccl27	isoform ratio	ENSRNOT00000060594	0.13	54	0.13	8.2e-14	-5.37	7.85e-08	0.4	FALSE
Liver	Ddx58	intron excision ratio	chr5:55347696:55349132	0.04	2296	0.03	7.9e-04	5.67	1.40e-08	0.48	FALSE
Liver	Aptx	intron excision ratio	chr5:55811580:55813276	0.07	1	0.06	8.7e-07	-5.58	2.39e-08	0.9	FALSE
Liver	Aptx	intron excision ratio	chr5:55811580:55813754	0.54	222	0.45	9.1e-56	5.31	1.09e-07	0.75	FALSE
Liver	Aptx	intron excision ratio	chr5:55813542:55813754	0.08	1	0.06	3.4e-07	-5.11	3.20e-07	0.4	FALSE
Liver	Atp8b5p	intron excision ratio	chr5:57583252:57586245	0.03	1578	0.02	2.3e-03	-5.14	2.69e-07	0.55	FALSE
Liver	Ddx58	mRNA stability	ENSRNOG00000006384	0.04	2296	0.01	1.2e-02	5.65	1.57e-08	0.41	FALSE
Liver	Atp8b5p	mRNA stability	ENSRNOG00000021704	0.16	11	0.15	1.5e-16	5.25	1.51e-07	0.67	FALSE
Liver	Vcp	mRNA stability	ENSRNOG00000034242	0.03	3	0.02	1.1e-03	-5.46	4.88e-08	0.45	FALSE
NAcc	Aptx	gene expression	ENSRNOG00000006582	0.13	1	0.12	1.8e-09	5.39	7.00e-08	0.79	FALSE
NAcc	Gba2	gene expression	ENSRNOG00000016364	0.05	1803	0.05	9.9e-05	-5.26	1.45e-07	0.64	FALSE
NAcc	Ca9	gene expression	ENSRNOG00000017073	0.08	1640	0.09	6.7e-07	-5.4	6.57e-08	0.75	FALSE
NAcc	Arhgef39	gene expression	ENSRNOG00000021433	0.06	1621	0.05	1.7e-04	5.14	2.74e-07	0.55	FALSE
NAcc	Atp8b5p	gene expression	ENSRNOG00000021704	0.14	20	0.16	6.7e-12	5.39	7.01e-08	0.57	FALSE
NAcc	Aptx	isoform ratio	ENSRNOT00000046463	0.28	1	0.18	1.1e-13	-5.38	7.55e-08	0.77	FALSE
NAcc	Aptx	isoform ratio	ENSRNOT00000094147	0.58	24	0.46	2.2e-37	5.4	6.64e-08	0.8	FALSE
NAcc	Unc13b	isoform ratio	ENSRNOT00000078274	0.1	1657	0.1	5.4e-08	-5.43	5.68e-08	0.58	FALSE
NAcc	Aptx	intron excision ratio	chr5:55811580:55813276	0.08	3	0.06	5.9e-05	-5.63	1.82e-08	0.69	FALSE
NAcc	Phf24	mRNA stability	ENSRNOG00000000129	0.06	1	0.04	3.1e-04	-5.46	4.69e-08	0.1	FALSE
NAcc	Vcp	mRNA stability	ENSRNOG00000034242	0.03	1	0.01	5.4e-02	5.49	3.94e-08	0.04	FALSE
NAcc	Rusc2	mRNA stability	ENSRNOG00000045843	0.04	1624	0.01	4.8e-02	-5.3	1.17e-07	0.54	FALSE
OFC	Ddx58	gene expression	ENSRNOG00000006384	0.44	1	0.34	6.6e-09	-5.13	2.93e-07	0.18	FALSE
OFC	Unc13b	isoform ratio	ENSRNOT00000078274	0.2	1	0.09	4.2e-03	-5.61	2.04e-08	0.06	FALSE
PL	Ddx58	alternative TSS	ENSRNOT00000107881	0.08	2295	0.09	2.2e-07	5.46	4.79e-08	0.2	FALSE
PL	Ddx58	alternative TSS	ENSRNOT00000107968	0.08	2295	0.09	1.7e-07	-5.5	3.83e-08	0.22	FALSE
PL	Ddx58	alternative TSS	ENSRNOT00000060765	0.1	2295	0.1	4.2e-08	-5.61	2.06e-08	0.24	FALSE
PL	Ddx58	alternative TSS	ENSRNOT00000107881	0.1	2295	0.1	4.1e-08	5.59	2.28e-08	0.23	FALSE
PL	Aco1	gene expression	ENSRNOG00000005849	0.04	1	0.04	9.2e-04	5.37	7.95e-08	0.15	FALSE
PL	Ubap1	gene expression	ENSRNOG00000012004	0.06	1181	0.03	1.6e-03	5.5	3.91e-08	0.72	FALSE
PL	Tmem8b	gene expression	ENSRNOG00000015664	0.07	1819	0.06	1.1e-05	-5.1	3.35e-07	0.54	FALSE
PL	Cd72	gene expression	ENSRNOG00000017485	0.05	1607	0.04	3.2e-04	5.36	8.24e-08	0.65	FALSE
PL	Atp8b5p	gene expression	ENSRNOG00000021704	0.09	5	0.08	1.7e-06	5.22	1.76e-07	0.49	FALSE
PL	Ccl21	gene expression	ENSRNOG00000034290	0.13	24	0.14	6.6e-11	-5.82	5.83e-09	0.63	FALSE
PL	Tmem215	gene expression	ENSRNOG00000042246	0.14	2153	0.15	2.4e-11	5.54	3.01e-08	0.64	FALSE
PL	Dcaf12	gene expression	ENSRNOG00000050790	0.05	1	0.03	3.4e-03	5.58	2.40e-08	0.05	FALSE
PL	ENSRNOG00000068351	gene expression	ENSRNOG00000068351	0.16	91	0.17	1.3e-12	-5.32	1.07e-07	0.56	FALSE
PL	Ddx58	isoform ratio	ENSRNOT00000060765	0.05	2295	0.05	1.2e-04	-5.25	1.50e-07	0.18	FALSE
PL	Ddx58	isoform ratio	ENSRNOT00000107881	0.09	2295	0.1	2.8e-08	5.3	1.14e-07	0.09	FALSE
PL	Aptx	isoform ratio	ENSRNOT00000046463	0.33	1	0.14	8.5e-11	-5.37	7.95e-08	0.76	FALSE
PL	Aptx	isoform ratio	ENSRNOT00000094147	0.6	1	0.47	3.5e-39	5.37	7.95e-08	0.76	FALSE
PL	Unc13b	isoform ratio	ENSRNOT00000067281	0.11	23	0.1	2.5e-08	5.63	1.80e-08	0.66	FALSE
PL	Unc13b	isoform ratio	ENSRNOT00000078274	0.15	1	0.15	9.2e-12	-5.61	2.02e-08	0.68	FALSE
PL	Aptx	intron excision ratio	chr5:55811580:55813276	0.12	1	0.09	3.2e-07	-5.12	3.07e-07	0.46	FALSE
PL	Unc13b	intron excision ratio	chr5:57363638:57406741	0.05	1	0.05	7.4e-05	5.67	1.43e-08	0.12	FALSE
PL	Galt	intron excision ratio	chr5:56928114:56928234	0.04	1	0.03	2.5e-03	-5.62	1.90e-08	0.04	FALSE
PL	Galt	intron excision ratio	chr5:56928114:56928488	0.07	1	0.07	6.8e-06	5.76	8.35e-09	0.52	FALSE
PL	Reck	intron excision ratio	chr5:58159526:58162559	0.05	1	0.03	1.4e-03	5.47	4.50e-08	0.08	FALSE
PL	Smu1	mRNA stability	ENSRNOG00000007671	0.11	1	0.1	3.8e-08	-5.7	1.21e-08	0.95	FALSE
PL	Unc13b	mRNA stability	ENSRNOG00000008237	0.1	1	0.1	3.9e-08	-5.46	4.69e-08	0.48	FALSE
PL	Pigo	mRNA stability	ENSRNOG00000009930	0.08	4	0.08	1.1e-06	5.19	2.13e-07	0.52	FALSE
PL	Tesk1	mRNA stability	ENSRNOG00000053729	0.07	1628	0.07	5.8e-06	5.33	9.57e-08	0.64	FALSE