LOC120099978

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC120099978 0.52 0.16 5.1e-10 0.28 0.28 0.35 0.33 2.8e-07 2.4e-07 3.1e-09 1.6e-08
2 NAcc gene expression LOC120099978 0.15 0.07 0.0e+00 0.16 0.16 0.14 0.16 3.2e-18 1.1e-17 8.2e-16 9.8e-18
3 BLA gene expression LOC120099978 0.4 0.14 0.0e+00 0.37 0.38 0.37 0.38 1.2e-20 1.0e-21 1.4e-20 2.8e-21
4 LHb gene expression LOC120099978 0.31 0.16 2.6e-05 0.25 0.16 0.22 0.19 1.2e-06 1.4e-04 7.5e-06 2.6e-05
5 pVTA gene expression LOC120099978 0.41 0.15 8.0e-14 0.21 0.25 0.21 0.23 2.1e-09 4.4e-11 1.5e-09 1.5e-10
6 PL gene expression LOC120099978 0.46 0.15 0.0e+00 0.4 0.44 0.43 0.43 8.8e-47 9.0e-53 5.6e-52 6.1e-52
7 Brain gene expression LOC120099978 0.33 0.12 0.0e+00 0.21 0.26 0.25 0.25 5.8e-19 2.0e-24 5.4e-23 1.8e-23
8 Liver gene expression LOC120099978 0.04 0.03 1.3e-03 0.02 0.01 0.01 0.01 1.4e-03 7.0e-03 1.2e-02 7.7e-03
9 IL gene expression LOC120099978 0.33 0.17 1.1e-04 0.1 0.13 0.18 0.17 2.4e-03 5.3e-04 3.3e-05 8.5e-05
10 Adipose gene expression LOC120099978 0.2 0.1 4.0e-07 0.04 0.06 0.05 0.04 5.5e-05 5.6e-07 2.9e-06 2.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.32.23.61.70.8-1.50.8-1.2-1.6-1.91.01.9-1.8
Area under the delay curve0.20.30.9-0.8-0.30.1-0.30.0-0.1-0.0-1.00.4-0.8
BMI with tail3.310.617.73.02.8-3.72.8-3.5-3.9-3.92.54.2-1.2
BMI without tail1.22.44.31.21.3-1.81.3-1.9-1.8-1.81.22.1-0.2
Body weight3.715.519.44.04.1-4.44.1-4.4-4.3-4.13.73.91.4
Weight adjusted by age3.03.46.62.62.0-1.81.8-1.8-1.7-1.62.01.81.0
Bone surface5.49.613.83.72.8-3.32.8-2.9-3.5-3.72.93.3-1.3
Bone volume2.64.47.72.81.6-2.11.6-1.8-2.3-2.61.72.3-1.8
Breakpoint value in progressive ratio session3.94.28.02.82.2-2.12.1-2.0-2.1-2.11.91.80.6
Number of licking bursts0.40.50.91.00.7-0.70.7-0.6-0.7-0.80.50.7-0.2
Context. condit. distance diff. score2.22.64.4-2.1-1.71.7-1.71.61.71.6-1.7-1.4-0.6
Locomotion velocity, session 10.10.20.6-0.70.00.30.10.10.30.5-0.2-0.20.8
Locomotion distance, session 10.81.02.40.60.8-1.10.9-1.1-1.3-1.20.31.5-0.6
Locomotion velocity, session 22.93.44.21.92.0-2.02.0-2.0-2.0-1.91.81.90.6
Locomotion distance, session 21.01.32.50.91.1-1.31.1-1.4-1.4-1.30.61.60.1
Locomotion velocity, session 30.10.10.4-0.4-0.20.0-0.20.1-0.0-0.1-0.40.3-0.6
Locomotion distance, session 30.00.00.1-0.3-0.10.1-0.10.10.10.1-0.2-0.0-0.1
Stereotopy head waving bouts, day 30.50.61.2-0.9-1.00.7-1.10.70.70.7-1.0-0.3-0.6
Stereotopy head waving duration, day 30.81.01.7-0.9-1.21.0-1.31.00.90.8-1.2-0.6-1.0
Locomotion velocity, session 70.10.10.8-0.3-0.50.2-0.40.20.10.0-0.30.2-0.9
Locomotion distance, session 70.00.10.2-0.5-0.1-0.1-0.0-0.3-0.1-0.00.10.40.3
Stereotopy head waving bouts, day 70.30.32.50.2-0.50.2-0.50.40.1-0.2-0.3-0.1-1.6
Stereotopy head waving duration, day 71.51.83.11.71.0-1.40.9-1.2-1.5-1.81.21.4-1.2
Locomotion velocity, session 80.80.91.40.61.2-1.01.2-1.1-0.9-0.70.50.91.2
Locomotion distance, session 80.20.31.1-0.6-0.50.5-0.50.40.40.4-1.1-0.2-0.6
Degree of sensitization distance0.10.10.2-0.2-0.0-0.30.0-0.3-0.3-0.20.20.5-0.0
Degree of sensitization stereotypy0.91.02.11.50.7-1.00.7-0.7-1.0-1.31.00.7-1.0
Conditioned locomotion1.51.73.31.21.5-1.31.5-1.4-1.0-0.91.50.51.8
Cocaine response after cond. corrected1.41.63.4-1.8-1.41.3-1.41.21.41.4-1.1-1.10.1
Cocaine response after cond. not corrected1.01.22.7-1.7-1.21.1-1.21.01.11.0-1.0-0.6-0.2
Cocaine response before conditioning0.81.01.51.21.0-1.00.9-0.8-1.2-1.20.81.2-0.6
Saline control response3.95.16.42.22.4-2.52.5-2.5-2.5-2.32.02.30.8
Bone: connectivity density3.55.58.32.62.0-2.62.0-2.4-2.7-2.92.02.7-1.2
Bone: cortical apparent density0.20.20.70.10.5-0.40.6-0.5-0.3-0.30.40.20.8
Bone: cortical area0.81.23.11.81.3-1.01.3-1.0-0.9-0.91.20.50.7
Bone: cortical porosity0.20.20.60.60.1-0.50.2-0.5-0.6-0.6-0.00.8-0.6
Bone: cortical porosity0.60.71.21.10.6-0.90.6-0.9-1.0-0.90.61.1-0.1
Bone: cortical thickness2.94.87.92.32.6-2.02.5-2.2-1.7-1.52.61.12.8
Bone: cortical thickness0.91.05.30.11.1-0.71.0-1.0-0.4-0.20.90.22.3
Bone: cortical tissue density0.20.30.90.20.6-0.50.6-0.6-0.4-0.30.50.20.9
Condit. Reinf. active minus inactive responses0.30.30.60.10.5-0.60.5-0.5-0.7-0.70.50.8-0.5
Condit. Reinf. active-inactive response ratio0.10.10.4-0.20.2-0.20.2-0.1-0.3-0.40.10.4-0.6
Condit. Reinf. active responses0.20.20.30.10.4-0.50.4-0.4-0.6-0.60.50.5-0.3
Condit. Reinf. inactive responses0.00.00.10.1-0.1-0.1-0.0-0.0-0.1-0.10.2-0.0-0.2
Incentive salience index mean0.40.50.90.30.6-0.80.7-0.7-0.9-0.90.51.0-0.4
Condit. Reinf. lever presses0.30.30.50.50.6-0.70.7-0.6-0.7-0.70.40.60.0
Condit. Reinf. active minus inactive responses0.40.53.40.6-0.30.1-0.30.4-0.1-0.3-0.60.1-1.9
Condit. Reinf. active-inactive response ratio0.80.83.80.4-0.70.7-0.71.00.40.3-1.0-0.7-1.9
Condit. Reinf. active responses0.60.83.31.00.3-0.60.2-0.4-0.8-1.00.11.0-1.8
Condit. Reinf. inactive responses0.81.02.80.40.7-1.10.6-1.1-1.1-1.20.81.7-0.5
Condit. Reinf. lever presses3.24.47.02.62.1-2.22.1-1.9-2.3-2.41.92.1-0.6
Condit. Reinf. lever reinforcers received0.81.22.71.30.7-1.00.6-0.7-1.2-1.30.51.3-1.6
Conditioned reinforcement - actives0.20.20.50.3-0.50.5-0.30.50.50.4-0.6-0.7-0.1
Conditioned reinforcement - inactives5.36.08.4-1.9-2.72.7-2.62.92.52.3-2.3-2.5-1.9
Conditioned locomotion8.710.512.9-2.9-3.43.6-3.23.63.53.5-3.4-3.5-1.0
Patch foraging indifference point 0 sec0.10.10.5-0.4-0.40.1-0.20.30.1-0.1-0.3-0.1-0.7
Patch foraging indifference point AUC3.94.58.12.82.4-2.22.2-2.2-2.0-2.02.21.61.0
Delay disc. indifference point, 0s delay0.70.82.3-1.5-1.00.7-1.00.50.70.8-1.4-0.1-0.4
Delay disc. indifference point, 16s delay0.80.82.7-0.9-0.90.7-0.90.90.50.3-1.2-0.4-1.6
Delay disc. indifference point, 2s delay0.20.20.5-0.4-0.40.3-0.40.30.20.2-0.7-0.2-0.7
Delay disc. indifference point, 24s delay0.30.20.8-0.9-0.30.5-0.30.20.40.6-0.3-0.20.8
Delay disc. indifference point, 4s delay0.30.31.2-1.1-0.50.3-0.50.10.30.4-1.10.0-0.1
Delay disc. indifference point, 8s delay0.20.20.9-0.9-0.30.2-0.3-0.00.10.2-0.80.3-0.1
Indifference point function ln k9.312.920.5-4.5-3.83.8-3.83.73.73.8-3.7-3.1-0.8
Indifference point function log k9.312.920.5-4.5-3.83.8-3.83.73.73.8-3.7-3.1-0.8
Patch foraging total patch changes 0 sec0.00.10.2-0.5-0.30.2-0.20.20.20.2-0.2-0.2-0.0
Patch foraging total patch changes 12 sec5.36.98.32.92.8-2.92.9-2.8-2.7-2.82.52.40.8
Patch foraging total patch changes 18 sec0.81.12.21.50.9-1.10.9-1.0-1.0-1.21.10.8-0.2
Patch foraging total patch changes 24 sec2.32.94.22.02.0-1.72.0-1.8-1.6-1.51.41.31.2
Patch foraging total patch changes 6 sec1.52.22.81.21.5-1.71.6-1.6-1.6-1.71.41.60.1
Patch foraging time to switch 0 sec2.64.06.41.91.6-2.21.7-2.1-2.4-2.51.72.4-0.8
Patch foraging water rate 0 sec5.28.311.9-2.7-2.73.2-2.73.13.33.3-2.8-3.50.1
Patch foraging water rate 12 sec10.315.821.8-4.3-3.84.3-3.94.04.54.7-4.0-4.10.6
Patch foraging water rate 18 sec3.85.17.2-2.7-2.12.4-2.02.32.52.6-2.6-2.10.0
Patch foraging water rate 24 sec5.67.810.9-3.0-2.53.1-2.62.93.23.3-2.8-3.10.3
Patch foraging water rate 6 sec4.87.110.1-3.1-2.32.8-2.42.63.03.2-2.7-2.80.9
Seeking ratio, delayed vs. immediate footshock0.20.20.7-0.40.1-0.2-0.1-0.1-0.3-0.3-0.30.8-0.8
Distance traveled before self-admin0.40.41.01.00.8-0.60.6-0.6-0.7-0.70.70.4-0.1
Distance traveled after self-admin0.20.20.70.80.5-0.40.4-0.3-0.5-0.50.60.3-0.3
Extensor digitorum longus weight7.429.135.65.46.0-5.86.0-5.9-5.5-5.25.74.83.1
Bone: elastic displacement1.51.72.9-1.3-0.91.3-1.01.01.51.7-1.1-1.61.5
Bone: elastic work0.81.04.90.61.1-0.81.1-1.0-0.5-0.20.80.12.2
Bone: endosteal estimation0.81.65.3-1.0-1.51.1-1.41.30.70.6-1.5-0.4-2.3
Bone: endosteal perimeter1.12.410.9-0.5-1.61.1-1.51.50.60.3-1.9-0.3-3.3
Epididymis fat weight2.55.98.8-2.2-3.02.5-2.82.62.42.2-2.3-2.2-1.9
Delta time in closed arm before/after self-admin0.40.31.8-0.30.3-0.20.2-0.50.10.21.00.21.4
Delta time in open arm before/after self-admin0.10.10.70.80.0-0.10.20.1-0.1-0.20.3-0.3-0.4
Diff in mean of infusions in LGA sessions0.50.61.51.20.8-0.70.8-0.6-0.5-0.61.10.20.6
Delay discount exponential model param0.20.20.70.80.3-0.10.30.00.10.00.8-0.40.6
Extinction: sum of active levers before priming5.35.38.12.82.4-2.52.3-2.4-2.5-2.61.72.40.3
Active lever presses in extinction session 62.42.34.62.21.7-1.41.7-1.3-1.3-1.22.10.81.1
Bone: final force2.74.35.92.42.3-2.22.3-2.2-2.2-2.12.11.90.5
Bone: final moment2.33.85.12.32.1-2.02.2-2.0-2.1-2.01.91.80.5
Food consumed during 24 hour testing period0.10.10.40.60.20.00.20.1-0.0-0.0-0.3-0.20.0
Glucose1.62.44.7-1.6-1.81.3-1.91.51.10.9-1.7-0.7-2.2
Heart weight2.94.26.9-2.6-2.52.0-2.42.12.01.8-1.5-1.8-1.3
Delay discount hyperbolic model param0.20.20.60.70.2-0.10.20.00.10.00.8-0.30.5
Intermittent access intake day 1-15 change0.60.51.30.0-0.60.9-0.61.00.90.8-0.4-1.2-0.0
Intermittent access intake escalation0.40.40.8-0.0-0.60.7-0.60.80.80.7-0.4-0.9-0.3
Intermittent access intake escalation 20.30.31.00.2-0.30.6-0.40.70.70.6-0.2-1.00.3
Intermitt. access day 1 inactive lever presses2.22.43.0-1.7-1.61.5-1.71.71.41.2-1.3-1.7-1.4
Intermitt. access day 15 inactive lever presses1.61.82.5-0.9-1.41.4-1.31.61.21.0-1.4-1.4-1.5
Intermitt. access escalation Index3.53.15.2-2.3-1.91.7-1.81.71.61.7-2.1-1.3-1.2
Intermittent access day 1 total infusions3.74.310.0-2.2-2.51.8-2.42.01.51.2-2.1-0.9-3.2
Intermittent access day 15 total infusions5.76.48.4-2.1-2.92.7-2.82.92.42.1-2.5-2.2-2.7
Intermittent access terminal intake (last 3 days)3.84.26.8-1.6-2.42.1-2.32.31.81.5-1.8-1.7-2.6
Intermittent access total infusions2.73.07.9-1.5-2.11.6-1.91.81.31.0-1.7-0.9-2.8
Intermittent access day 1 locomotion2.42.56.4-2.2-1.91.2-1.81.30.90.7-1.6-0.4-2.5
Intermittent access day 15 total locomotion3.43.75.3-1.5-2.22.0-2.12.21.71.5-2.0-1.4-2.3
Intermittent access total locomotion4.45.012.0-2.0-2.62.0-2.52.31.71.3-2.4-1.1-3.5
Intermittent access standard deviation0.90.91.4-0.7-1.01.1-1.01.21.11.1-0.5-1.1-0.3
Left kidney weight0.82.34.5-0.8-1.41.6-1.51.71.71.6-1.4-2.1-0.4
Right kidney weight0.30.82.70.3-0.60.9-0.51.11.00.8-0.7-1.6-0.3
Cocaine induced anxiety0.00.00.10.2-0.10.0-0.10.10.10.00.3-0.20.2
Post-drug Anxiety1.11.22.61.61.2-1.01.1-1.0-0.9-0.91.40.41.1
Baseline Anxiety2.12.23.41.81.8-1.51.8-1.6-1.4-1.31.41.01.1
Tail length0.51.47.60.71.3-0.71.3-1.0-0.4-0.10.9-0.02.8
Length with tail1.86.89.32.63.0-2.63.0-2.8-2.3-2.02.81.62.9
Length without tail2.75.97.52.72.6-2.62.7-2.6-2.5-2.32.42.11.3
Times rat made contact with spout0.60.71.20.50.8-0.90.7-1.0-0.9-0.90.71.10.1
Lifetime Intake2.32.66.9-1.5-1.91.4-1.81.61.20.9-1.6-0.8-2.6
Liver weight, left0.20.20.4-0.5-0.30.5-0.40.40.60.7-0.4-0.50.4
Liver weight, right0.10.20.6-0.8-0.20.3-0.30.20.40.6-0.7-0.20.7
Locomotor activity2.13.35.1-2.2-1.72.0-1.61.72.12.3-1.6-1.80.7
Locomotor testing distance2.94.88.1-2.8-2.12.3-2.02.02.42.7-2.1-2.00.9
Locomotor testing rearing1.93.05.5-2.4-1.91.8-1.91.61.81.9-1.6-1.3-0.2
Locomotion in novel chamber4.65.77.8-2.2-2.32.6-2.42.82.42.3-2.7-2.2-1.8
Locomotion in novel chamber post-restriction2.83.44.3-1.9-1.92.0-1.92.01.91.9-1.6-2.1-1.0
Fecal boli incidents, locomotor time 10.20.21.11.0-0.1-0.20.00.1-0.1-0.40.4-0.1-0.4
Change in fecal boli incidents, locomotor task0.20.10.6-0.80.0-0.10.0-0.3-0.2-0.00.00.80.2
Time >=10cm from walls, locomotor time 10.90.96.0-0.3-0.90.4-0.90.70.1-0.2-0.60.5-2.5
Bouts of movement, locomotor time 11.21.41.81.41.3-1.21.3-1.1-1.2-1.31.21.00.2
Total resting periods, locomotor time 11.01.01.71.31.1-1.11.1-0.9-1.1-1.20.90.9-0.1
Rest time, locomotor task time 11.71.92.5-1.3-1.31.5-1.31.61.41.4-1.4-1.6-0.4
Distance moved, locomotor task time 10.40.51.10.50.6-0.70.5-0.7-0.8-0.80.51.0-0.6
Vertical activity count, locomotor time 10.91.01.3-0.9-1.11.1-1.11.01.21.1-1.0-0.8-0.2
Time >=10cm from walls, locomotor time 20.10.10.50.10.00.10.00.2-0.1-0.2-0.20.1-0.7
Bouts of movement, locomotor time 20.60.70.90.80.8-0.90.8-0.9-0.9-0.90.80.80.3
Total resting periods, locomotor time 20.40.40.60.60.6-0.70.6-0.7-0.7-0.80.60.60.0
Rest time, locomotor task time 22.52.93.6-1.8-1.91.8-1.91.81.81.7-1.8-1.6-0.7
Distance moved, locomotor task time 21.11.32.01.21.4-1.21.4-1.2-1.2-1.11.11.20.5
Vertical activity count, locomotor time 20.30.42.4-0.20.10.30.10.10.50.70.1-0.41.6
Light reinforcement 10.20.40.5-0.6-0.70.7-0.60.60.70.7-0.6-0.60.2
Light reinforcement 20.91.32.2-0.4-1.11.3-1.21.51.10.9-1.1-1.3-1.1
Bone: marrow area0.81.75.2-1.0-1.51.1-1.51.30.80.7-1.5-0.5-2.3
Bone: maximum diameter0.20.31.41.20.5-0.30.5-0.1-0.5-0.50.20.1-0.5
Bone: maximum force3.96.79.03.02.6-2.82.6-2.6-2.9-3.02.32.6-0.7
Bone: maximum moment3.35.77.72.72.4-2.62.4-2.4-2.7-2.82.02.4-0.6
Mean time between licks in bursts0.30.51.3-0.10.7-0.60.8-0.8-0.6-0.30.50.81.1
Mean num. licks in bursts0.20.20.9-0.9-0.50.3-0.50.30.40.4-0.4-0.2-0.1
Cd content in liver1.41.52.6-0.6-1.21.5-1.21.61.41.4-0.8-1.6-0.5
Co content in liver2.32.74.5-1.9-1.41.7-1.41.31.92.1-1.3-1.71.5
Cu content in liver0.40.50.70.80.7-0.80.7-0.8-0.8-0.80.50.8-0.1
Fe content in liver0.10.20.70.80.3-0.30.4-0.3-0.3-0.20.30.00.4
K content in liver2.32.33.61.01.4-1.81.5-1.7-1.8-1.91.01.9-0.4
Mg content in liver1.01.02.90.30.3-1.00.4-0.8-1.2-1.30.01.5-1.7
Mn content in liver3.03.45.12.22.0-2.01.9-1.9-2.0-2.11.81.50.1
Na content in liver0.70.71.71.31.1-0.81.1-0.7-0.8-0.70.40.40.6
Rb content in liver0.91.22.2-1.2-1.40.9-1.31.00.80.7-1.0-0.3-1.5
Se content in liver0.50.62.41.40.2-0.40.2-0.2-0.6-0.80.20.3-1.6
Sr content in liver2.32.13.41.51.7-1.41.7-1.4-1.2-1.21.80.81.4
Zn content in liver1.31.41.71.31.2-1.31.2-1.3-1.3-1.31.11.20.3
Bone: minimum diameter0.61.16.0-0.5-1.10.5-1.10.80.30.0-1.00.0-2.5
Time in familiar zone, hab. session 10.20.20.8-0.6-0.40.2-0.40.40.10.0-0.70.2-0.9
Time in novel zone, hab. session 10.50.50.9-0.7-0.50.7-0.50.50.81.0-0.1-0.80.9
Total zone transitions, hab. session 10.91.21.51.01.2-1.21.2-1.2-1.2-1.11.01.20.3
Total locomotion distance, hab. session 10.20.30.5-0.6-0.70.6-0.70.60.50.5-0.5-0.4-0.5
Locomotion velocity, hab. session 10.00.00.1-0.1-0.10.1-0.20.10.10.1-0.1-0.0-0.3
Time in familiar zone, hab. session 20.20.21.8-0.4-0.10.2-0.0-0.10.30.50.0-0.11.4
Time in novel zone, hab. session 20.30.31.40.30.2-0.40.2-0.2-0.6-0.70.20.5-1.2
Total zone transitions, hab. session 22.43.16.11.51.4-1.91.3-1.8-2.1-2.21.12.5-1.3
Total locomotion distance, hab. session 20.20.31.4-0.0-0.1-0.3-0.2-0.2-0.4-0.5-0.20.8-1.2
Locomotion velocity, hab. session 20.20.32.0-0.1-0.3-0.1-0.40.0-0.2-0.3-0.50.6-1.4
Novel to familiar place preference ratio1.41.42.41.41.1-1.21.0-0.9-1.3-1.51.11.0-1.0
Novelty place preference0.70.71.41.00.7-0.80.6-0.5-1.0-1.20.70.7-1.1
Time in novel zone, NPP test0.50.51.10.80.6-0.70.5-0.5-0.8-1.00.60.6-1.0
Total zone transitions, NPP test2.23.14.41.81.8-1.91.8-1.9-2.1-2.01.22.1-0.1
Total locomotion distance, NPP test0.10.10.20.20.1-0.20.1-0.2-0.3-0.3-0.20.4-0.4
Locomotion velocity, NPP test0.10.10.20.30.2-0.30.2-0.3-0.4-0.3-0.20.4-0.3
Intraocular pressure1.11.53.8-0.5-1.21.3-1.21.41.51.2-1.1-1.9-0.1
Delta distance traveled before/after self-admin0.00.00.0-0.1-0.10.1-0.00.10.10.1-0.1-0.10.1
Delta ambulatory time before/after self-admin0.00.00.1-0.1-0.00.00.0-0.00.10.1-0.00.10.4
Parametrial fat weight2.24.27.0-1.5-2.62.0-2.62.12.01.6-2.1-1.8-2.0
Pavlov. Cond. lever latency0.20.20.3-0.5-0.40.5-0.50.50.60.6-0.4-0.6-0.0
Pavlov. Cond. magazine entry latency0.30.41.60.50.1-0.60.3-0.4-0.7-0.90.20.8-1.3
Pavlov. Cond. change in total contacts0.30.31.60.70.1-0.20.10.0-0.4-0.6-0.10.3-1.2
Pavlov. Cond. index score0.10.10.20.50.1-0.30.2-0.1-0.4-0.40.10.3-0.4
Pavlov. Cond. latency score0.00.00.10.2-0.0-0.20.1-0.1-0.2-0.30.00.2-0.4
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.1-0.1-0.0-0.1-0.1-0.10.00.10.0
Pavlov. Cond. magazine entry number0.20.20.6-0.8-0.40.4-0.50.20.50.6-0.5-0.20.3
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.2-0.40.6-0.40.60.60.6-0.2-0.9-0.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.70.4-0.50.5-0.4-0.6-0.70.30.5-0.3
Pavlov. Cond. response bias0.10.10.20.40.1-0.20.3-0.1-0.3-0.40.20.1-0.3
Pavlov. Cond. lever latency0.71.02.4-1.6-1.01.0-0.90.81.11.2-0.8-0.80.4
Pavlov. Cond. magazine entry latency4.85.67.32.32.4-2.62.4-2.4-2.7-2.72.22.7-0.2
Pavlov. Cond. change in total contacts2.94.08.02.81.9-2.01.8-1.7-2.3-2.51.61.8-1.3
Pavlov. Cond. index score3.34.26.42.52.1-2.22.1-1.9-2.3-2.41.72.1-0.5
Pavlov. Cond. latency score2.73.45.32.31.9-1.91.9-1.7-2.1-2.21.51.8-0.5
Pavlov. Cond. lever contacts0.60.82.21.51.0-0.90.9-0.7-0.9-1.00.70.6-0.1
Pavlov. Cond. magazine entry number7.99.712.4-3.4-3.23.3-3.23.13.53.5-3.0-3.30.1
Pavlov. Cond. intertrial magazine entries1.31.72.1-1.2-1.41.5-1.41.51.51.4-1.2-1.4-0.5
Pavlov. Cond. lever-magazine prob. diff.3.94.97.22.72.3-2.42.3-2.1-2.5-2.61.92.3-0.4
Pavlov. Cond. response bias2.33.15.22.31.8-1.81.8-1.6-1.9-2.01.61.7-0.3
Time in closed arm before self-admin0.10.10.60.3-0.0-0.1-0.00.0-0.3-0.3-0.20.1-0.8
Time in closed arm after self-admin0.00.00.3-0.3-0.0-0.0-0.1-0.1-0.00.00.50.10.2
Time in open arm before self-admin0.60.72.5-1.6-0.60.7-0.70.40.81.0-0.6-0.40.7
Time in open arm after self-admin0.30.30.7-0.5-0.50.6-0.40.50.70.7-0.2-0.90.4
Bone: periosteal estimation0.10.10.80.7-0.10.0-0.00.1-0.1-0.2-0.0-0.1-0.9
Bone: periosteal perimeter0.30.51.41.20.4-0.50.4-0.3-0.7-0.80.10.5-1.1
Bone: post-yield work2.73.615.11.60.6-1.50.6-0.9-2.0-2.40.42.2-3.9
Progressive ratio test 1 active lever presses2.02.12.7-1.4-1.71.5-1.61.61.41.2-1.4-1.2-1.4
Progressive ratio test 1 breakpoint1.81.82.4-1.3-1.61.5-1.51.51.41.2-1.2-1.2-1.1
Progressive ratio test 1 inactive lever presses0.91.01.9-1.4-1.11.0-1.11.00.90.8-0.9-0.6-1.0
Progressive ratio test 2 active lever presses2.83.04.1-1.4-2.01.8-1.82.01.61.4-1.7-1.4-2.0
Progressive ratio test 2 breakpoint3.94.45.7-1.9-2.32.3-2.22.42.11.9-2.0-2.0-1.7
Progressive ratio test 2 inactive lever presses6.77.810.1-2.7-3.22.9-3.13.12.62.3-2.8-2.2-2.9
Incentive Sensitization - Responses0.20.21.50.1-0.50.3-0.30.40.1-0.0-0.3-0.2-1.2
Incentive Sensitization - Breakpoint0.30.31.6-0.1-0.70.5-0.50.70.30.2-0.5-0.4-1.3
Sum of active levers in priming session hrs 5-61.41.45.22.31.4-0.91.5-0.7-0.8-0.81.10.20.9
Progressive ratio2.93.45.21.71.7-2.01.4-1.9-2.1-2.21.62.3-1.0
Food seeking constrained by brief footshock0.30.30.90.10.6-0.50.6-0.6-0.4-0.30.50.50.9
Seeking ratio, punishment vs. effort2.42.94.7-1.9-1.61.8-1.31.51.92.2-1.6-1.81.3
Retroperitoneal fat weight5.016.621.7-4.0-4.74.2-4.54.44.03.7-4.3-3.7-2.9
Reaction time number correct0.20.31.00.50.5-0.40.6-0.5-0.3-0.20.8-0.01.0
Reaction time mean minus median3.44.57.02.62.3-2.22.1-2.1-2.2-2.32.41.80.1
Reaction time mean minus median AUC1.82.34.11.91.7-1.51.6-1.5-1.4-1.42.01.00.9
Reaction time num false alarms0.60.92.4-1.5-0.40.7-0.40.40.91.1-0.7-0.81.5
Reaction time num false alarms AUC0.30.43.1-0.80.3-0.00.3-0.40.10.40.1-0.11.8
Reaction time trials correct on left0.20.31.00.50.5-0.40.6-0.5-0.3-0.20.8-0.01.0
Reaction time trials on left0.30.41.30.60.6-0.50.7-0.5-0.3-0.30.90.01.1
Reaction time mean0.00.10.20.30.3-0.10.2-0.0-0.2-0.30.40.2-0.4
Reaction time mean AUC0.10.10.40.20.2-0.10.10.0-0.2-0.30.30.2-0.6
Median of all reaction times0.10.10.4-0.3-0.20.3-0.30.40.20.2-0.1-0.0-0.6
Reaction time omissions1.52.03.11.51.4-1.51.4-1.5-1.3-1.41.81.21.0
Reaction time false alarm rate0.30.51.7-1.3-0.30.5-0.40.20.60.8-0.6-0.41.1
Reaction time premature initiation rate1.82.43.80.52.0-1.61.8-1.8-1.4-1.21.31.51.9
Reaction time premature initiations2.84.06.31.12.5-2.02.4-2.3-1.8-1.52.01.62.5
Std. dev. reaction times0.91.21.91.41.2-1.11.1-1.0-1.1-1.21.30.90.0
Reaction time trials completed0.30.41.30.60.6-0.50.7-0.5-0.3-0.30.90.01.1
Reaction time trials AUC0.20.21.10.40.4-0.30.5-0.4-0.2-0.10.7-0.11.0
Run reversals in cocaine runway, females0.80.82.3-0.20.4-1.00.7-1.1-1.0-0.90.81.50.2
Run reversals in cocaine runway, males0.90.92.6-0.7-0.40.9-0.40.71.11.20.2-1.31.6
Latency to leave start box in cocaine runway0.20.21.4-0.00.1-0.3-0.0-0.1-0.5-0.60.10.3-1.2
Latency to leave start box in cocaine runway, F0.10.10.60.00.2-0.30.1-0.2-0.4-0.40.00.3-0.8
Latency to leave start box in cocaine runway, M0.00.00.10.10.0-0.10.1-0.1-0.2-0.30.40.1-0.3
Std. dev. time between licks in bursts0.50.62.7-1.0-0.30.5-0.30.20.71.0-0.3-0.61.7
Total sessions with >9 infusions1.11.21.8-1.3-1.31.0-1.31.00.90.7-1.1-0.5-1.3
Short access day 1 total inactive lever presses3.33.74.8-1.9-2.22.0-2.02.11.91.8-1.9-1.8-1.6
Short access day 10 total inactive lever presses3.63.98.5-2.9-2.12.0-2.02.02.01.9-1.5-2.0-0.6
Short access day 1 total infusions2.32.45.5-1.7-1.91.3-1.71.51.10.9-1.7-0.9-2.3
Short access day 10 total infusions0.91.07.6-0.5-0.90.2-0.90.4-0.1-0.4-0.50.7-2.8
Short access total infusions0.70.83.3-1.0-1.10.6-1.00.70.40.2-0.9-0.0-1.8
Short access day 1 locomotion1.41.54.6-1.6-1.40.9-1.21.10.70.5-1.4-0.2-2.1
Short access day 10 total locomotion0.91.14.0-1.3-1.10.6-1.10.80.40.3-1.10.2-2.0
Short access total locomotion0.90.93.3-1.4-1.10.6-0.90.70.40.2-0.90.2-1.8
One hour access (0.3 mA shock)8.39.711.8-3.4-3.43.2-3.43.43.12.8-3.3-2.7-2.3
Compulsive drug intake2.22.25.20.91.7-1.51.6-1.8-1.2-0.91.01.22.3
One hour access (shock baseline)7.18.311.2-2.5-3.33.0-3.13.32.82.4-2.6-2.7-3.0
Social response proportion1.01.01.81.00.8-1.11.0-1.0-1.3-1.30.61.2-0.4
Social responses0.20.30.40.50.4-0.60.7-0.7-0.5-0.50.30.50.6
Social time0.30.40.60.50.6-0.60.8-0.7-0.5-0.40.40.60.7
Soleus weight4.713.718.7-3.6-3.74.0-3.83.93.93.9-4.3-3.7-1.0
Bone: stiffness3.35.27.62.52.1-2.42.2-2.1-2.6-2.82.22.4-1.1
Tibialis anterior weight9.833.544.36.26.6-5.96.7-6.1-5.5-5.16.44.44.4
Time to tail flick, vehicle, before self-admin0.60.71.10.50.7-0.90.6-0.8-0.9-1.01.01.1-0.2
Time to tail flick, vehicle, after self-admin1.51.62.50.71.1-1.41.2-1.5-1.3-1.31.61.60.6
Time to tail flick, test, before self-admin0.40.41.9-1.4-0.70.4-0.60.30.30.3-0.60.2-0.9
Time to tail flick, test, after self-admin0.00.00.1-0.10.00.00.00.0-0.0-0.00.20.20.1
Delta time to tail flick, vehicle, before/after SA0.50.50.90.40.6-0.80.7-0.9-0.8-0.80.71.00.2
Delta time to tail flick, test, before/after SA0.90.82.61.30.9-0.60.8-0.6-0.4-0.31.10.11.6
Tibia length1.02.811.13.31.9-1.41.8-1.3-1.4-1.41.30.50.7
Ambulatory time before self-admin0.50.51.01.00.7-0.60.6-0.4-0.8-0.90.60.4-0.7
Ambulatory time after self-admin0.30.32.40.3-0.20.0-0.30.3-0.2-0.40.10.1-1.6
Bone: tissue strength0.20.20.80.70.2-0.30.2-0.1-0.4-0.50.10.3-0.9
Total heroin consumption5.26.09.93.22.7-2.62.7-2.6-2.5-2.51.92.01.2
Bone: trabecular number1.62.54.32.10.9-1.61.0-1.3-1.7-2.01.21.8-1.8
Bone: trabecular spacing0.60.82.5-1.6-0.60.8-0.60.60.91.0-1.0-0.80.7
Bone: trabecular thickness0.40.42.80.5-0.60.2-0.60.3-0.0-0.2-0.50.3-1.7
Bone: trabecular tissue density4.05.77.4-1.8-2.52.7-2.42.72.62.6-2.4-2.7-0.7
Water consumed over 24 hours0.80.91.21.01.0-1.11.0-1.1-1.0-1.00.71.10.3
Number of responses in last shaping day1.31.32.6-1.6-1.21.2-1.01.11.21.2-0.9-1.30.1