Hub : Traits

Tail length

Tags: Physiology

Project: dissection

646 significantly associated models · 182 unique genes

Significant Loci

# chr p0 p1 # assoc genes # joint models best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 11614321 13009428 1 1 6.0e-08 3.4e-08 3.1e-90 -1232 Cited2
2 1 84851092 86245863 1 1 1.8e-07 7.4e-06 1.6e-09 -81 Clip3
3 1 153885348 158950354 21 5 5.3e-08 2.3e-08 1.0e+00 100 Fchsd2 Folr1 Hbb-b1 Trim68 Hbb-bs
4 2 34186973 35996814 6 1 1.7e-07 1.2e-07 1.0e+00 100 Nln
5 2 90636696 92031287 1 1 3.9e-11 1.2e-01 5.0e-02 -60 Snx16
6 3 121364624 123489307 2 1 6.9e-09 6.3e-10 2.1e-02 86 Plcb1
7 4 127937446 129330831 1 1 2.3e-07 4.7e-08 1.0e+00 100 NA
8 6 100080023 100868818 1 1 2.3e-07 3.3e-06 4.2e-01 97 Galnt16
9 7 16845355 16970279 1 1 7.6e-62 NaN NA NA NA
10 7 26902995 30904027 20 5 3.3e-13 2.1e-13 NaN NaN Vezt Ndufa12 Plxnc1 Socs2 Nudt4
11 9 50034515 51433051 1 1 2.7e-07 8.2e-08 9.2e-02 90 Tmeff2
12 9 52642068 54039163 1 1 3.3e-07 1.4e-07 1.0e+00 100 NA
13 9 54140250 57601104 19 1 2.4e-12 1.4e-12 1.0e+00 100 Hecw2
14 9 58867167 60264237 1 1 1.9e-08 2.5e-07 3.6e-04 52 Kctd18
15 9 67312343 69247638 6 1 1.5e-08 1.3e-08 1.3e-01 93 NA
16 10 79556862 83433454 41 6 1.4e-14 9.3e-15 1.0e+00 100 Phospho1 Ube2z Hoxb9 Pip4k2b Npepps Cdk5rap3
17 10 105364159 107179560 6 1 1.1e-07 2.4e-07 1.0e+00 100 Dus1l
18 12 27006 5138463 21 5 5.8e-10 4.3e-09 1.0e+00 100 Camsap3 Trappc5 Elavl1 Pet100 NA
19 12 5928125 7775553 2 1 5.7e-09 6.1e-08 3.0e-01 96 Slc7a1
20 20 883910 4164571 23 1 3.0e-08 1.9e-06 9.4e-01 100 RT1-CE14
21 20 4988687 6657065 5 4 1.1e-07 3.0e-08 1.5e-39 -464 Rps10 Ilrun NA Nudt3

p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
BMI with tail 12.3 48 36 87.8 -0.98 2.3e-170 Snapc2 Spop Ttll6 Ngfr Phospho1 Abi3 Gip Snf8 Ube2z Atp5mc1 Hoxb9 Hoxb4 Hoxb3 NA Snx11 Cbx1 Nfe2l1 Copz2 Kpnb1 Tbkbp1 Osbpl7 Mrpl10 Lrrc46 Scrn2 Sp2 Mrpl45 Srcin1 Slc39a10 Acadl Pip4k2b Tmeff2 Zfp652 Kat7 Npepps Sp6 Skap1 Kctd18 Unc80 Pnpo Phb Cdk5rap3 Prr15l Psmb3 Dnah7 NA B4galnt2 Atp5mc1 NA
BMI without tail 20.1 14 2 4.9 0.97 2.8e-12 Lta4h Hal Ntn4 Vezt Cradd Snx16 Metap2 Ogfod3 Sectm1b Csnk1d Slc16a3 Ccdc57 Dus1l NA
Body weight 11.9 65 48 117.1 0.96 9.1e-107 RT1-S3 RT1-N3 Gnl1 Abcf1 Gtf2h4 Zfp958l1 Slc7a1 Mcoln1 Camsap3 Xab2 Pcp2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 Cers4 Stard13 N4bp2l2 Brca2 Cdk17 Elk3 Lta4h Hal Galnt16 Amdhd1 Ntn4 Vezt Ndufa12 Tmcc3 Cep83 Plxnc1 Cradd Socs2 Nudt4 Snx16 Metap2 AABR07056633.1 Prr3 Arhgef18 Lrrc8e Insr NA RT1-T24-1 Mir331 RT1-CE11 RT1-M6-2 RT1-T24-4 Ccdc57 Clip3 Pet100 AABR07044375.1 AABR07044397.1 Fgd6 Ddr1 Ube2n N4bp2l1 NA NA RT1-CE15 Zfp958 NA RT1-CE14 NA NA
Epididymis fat weight 26.1 9 4 9.8 0.30 3.9e-01 Rps10 RT1-S3 Taf11 RT1-T24-1 Ilrun RT1-T24-4 NA Nudt3 NA
Heart weight 11.4 1 0 0.0 0.00 1.0e+00 NA
Left kidney weight 12.3 24 21 51.2 0.99 7.8e-57 Zfp958l1 Mcoln1 Camsap3 Xab2 Pcp2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 Cers4 Stard13 N4bp2l2 Brca2 Vezt Metap2 Arhgef18 Lrrc8e Insr Pet100 N4bp2l1 NA Zfp958 NA
Right kidney weight 10.4 22 18 43.9 1.00 3.6e-71 Zfp958l1 Mcoln1 Camsap3 Xab2 Pcp2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 Cers4 Stard13 N4bp2l2 Brca2 Arhgef18 Lrrc8e Insr Pet100 N4bp2l1 NA Zfp958 NA
Length with tail 10.4 170 128 312.2 0.97 0.0e+00 Rps10 RT1-S3 RT1-N3 Gnl1 Abcf1 Gtf2h4 Zfp958l1 Slc7a1 Mcoln1 Camsap3 Xab2 Pcp2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 Cers4 Stard13 N4bp2l2 Brca2 Gtf3c3 Cdk17 Elk3 Lta4h Hal Galnt16 Spop Plcb1 Ttll6 Amdhd1 Ngfr Phospho1 Ntn4 Abi3 Gip Snf8 Vezt Ube2z Atp5mc1 Ndufa12 Hoxb9 Tmcc3 Cep83 Plxnc1 Hoxb4 Hoxb3 NA Cradd Snx11 Cbx1 Nfe2l1 Socs2 Nudt4 Copz2 Kpnb1 Tbkbp1 Osbpl7 Mrpl10 Lrrc46 Scrn2 Sp2 Mrpl45 Srcin1 Nln Slc39a10 Sgtb Trappc13 Trim23 Stk17b Acadl Pip4k2b Hecw2 Ccdc150 Pgap1 Sf3b1 Lancl1 Coq10b Hspd1 Mob4 Rftn2 Tmeff2 Zfp652 Trim21 Fchsd2 Atg16l2 Pde2a Art2b Inppl1 Folr2 Folr1 Lrrc51 Il18bp Rnf121 Trpc2 Nup98 Pgap2 Stim1 Ankrd44 Metap2 Kat7 Npepps Sp6 Skap1 AABR07056633.1 Taf11 Prr3 Kctd18 Arhgef18 Kansl1l Unc80 Lrrc8e Insr NA Mtus2 RT1-T24-1 Plcl1 Srek1 Plcb4 Mir331 Cisd3 Ilrun RT1-CE11 RT1-M6-2 Mrpl42 RT1-T24-4 Pnpo Phb Hbb-b1 Erbin Trim68 Cdk5rap3 NA Prr15l Clip3 Pet100 AABR07044375.1 AABR07044397.1 Psmb3 Boll Fgd6 Cited2 Ddr1 Ube2n NA N4bp2l1 Dnah7 Nudt3 Hbb-bs NA NA NA NA RT1-CE16 RT1-CE15 NA Zfp958 NA NA RT1-CE14 NA B4galnt2 NA NA Atp5mc1 NA NA NA NA Olr61
Length without tail 11.7 41 17 41.5 0.79 1.3e-24 Zfp958l1 Mcoln1 Camsap3 Xab2 Pcp2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 Cers4 Stard13 N4bp2l2 Brca2 Cdk17 Elk3 Lta4h Amdhd1 Ntn4 Vezt Ndufa12 Plxnc1 Cradd Socs2 Nln Trappc13 Trim23 Metap2 AABR07056633.1 Arhgef18 Lrrc8e Insr Srek1 Mir331 Erbin Pet100 Fgd6 N4bp2l1 NA Zfp958 NA
Liver weight, left 23.6 1 1 2.4 0.00 1.0e+00 NA
Liver weight, right 12.1 5 2 4.9 0.37 4.1e-01 Taf11 NA NA Nudt3 NA
Parametrial fat weight 26.4 1 1 2.4 0.00 1.0e+00 NA
Retroperitoneal fat weight 4.9 4 0 0.0 1.00 2.5e-05 Vezt Ogfod3 Slc16a3 Ccdc57
Intraocular pressure 29.4 1 1 2.4 0.00 1.0e+00 NA
Extensor digitorum longus weight 6.4 29 13 31.7 0.60 1.3e-08 Zfp958l1 Mcoln1 Camsap3 Xab2 Pcp2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 Cers4 Stard13 N4bp2l2 Brca2 Snx16 Nln Sgtb Trappc13 Arhgef18 Lrrc8e Insr Srek1 Cisd3 Erbin Pet100 N4bp2l1 NA Zfp958 NA
Soleus weight 9.8 6 3 7.3 0.94 1.4e-03 Rps10 Taf11 Ilrun NA Nudt3 NA
Tibialis anterior weight 9.7 23 19 46.3 0.65 3.3e-09 Zfp958l1 Mcoln1 Camsap3 Xab2 Pcp2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 Cers4 Stard13 N4bp2l2 Brca2 Snx16 Arhgef18 Lrrc8e Insr Pet100 N4bp2l1 NA Zfp958 NA
Tibia length 8.3 52 16 39.0 0.98 6.0e-89 Abcf1 Mcoln1 Stxbp2 Trappc5 Evi5l Snapc2 Brca2 Gtf3c3 Cdk17 Elk3 Lta4h Hal Amdhd1 Ntn4 Vezt Ndufa12 Tmcc3 Cep83 Plxnc1 Cradd Socs2 Nln Slc39a10 Sgtb Trappc13 Trim23 Stk17b Hecw2 Pgap1 Sf3b1 Coq10b Hspd1 Rftn2 Ankrd44 Metap2 AABR07056633.1 Lrrc8e Insr NA Plcl1 Srek1 Mir331 Erbin Ccdc57 Pet100 Boll Fgd6 NA NA NA NA NA
Number of licking bursts 155.0 1 1 2.4 0.00 1.0e+00 NA
Food consumed during 24 hour testing period 17.5 1 0 0.0 0.00 1.0e+00 NA
Times rat made contact with spout 75.1 1 1 2.4 0.00 1.0e+00 NA
Mean time between licks in bursts 54.9 1 1 2.4 0.00 1.0e+00 NA
Mean num. licks in bursts 164.2 1 1 2.4 0.00 1.0e+00 NA
Std. dev. time between licks in bursts 177.7 1 1 2.4 0.00 1.0e+00 NA
Indifference point 0 sec 18.7 1 1 2.4 0.00 1.0e+00 NA
Indifference point AUC 33.6 2 1 2.4 0.00 1.0e+00 Snx16 NA
Delay discounting total patch changes 0 sec 17.7 1 1 2.4 0.00 1.0e+00 NA
Delay discounting total patch changes 12 sec 102.7 1 1 2.4 0.00 1.0e+00 NA
Delay discounting total patch changes 18 sec 175.3 1 1 2.4 0.00 1.0e+00 NA
Delay discounting total patch changes 24 sec 28.3 1 1 2.4 0.00 1.0e+00 NA
Delay discounting total patch changes 6 sec 98.5 1 1 2.4 0.00 1.0e+00 NA
Delay discounting time to switch 0 sec 11.4 1 0 0.0 0.00 1.0e+00 Snx16
Delay discounting water rate 0 sec 11.8 1 0 0.0 0.00 1.0e+00 NA
Delay discounting water rate 12 sec 44.2 1 1 2.4 0.00 1.0e+00 NA
Delay discounting water rate 24 sec 62.7 1 1 2.4 0.00 1.0e+00 NA
Delay discounting water rate 6 sec 16.9 7 1 2.4 0.98 3.4e-14 Nln Sgtb Trappc13 Trim23 Srek1 Erbin NA
Locomotor testing distance 14.0 1 0 0.0 0.00 1.0e+00 NA
Locomotor testing rearing 23.9 1 1 2.4 0.00 1.0e+00 NA
Light reinforcement 1 39.9 2 1 2.4 0.00 1.0e+00 Kctd18 NA
Reaction time num false alarms 56.4 1 1 2.4 0.00 1.0e+00 NA
Reaction time num false alarms AUC 79.5 1 1 2.4 0.00 1.0e+00 NA
Reaction time mean 41.3 1 1 2.4 0.00 1.0e+00 NA
Reaction time mean AUC 58.0 1 1 2.4 0.00 1.0e+00 NA
Median of all reaction times 51.2 1 1 2.4 0.00 1.0e+00 NA
Reaction time omissions 11.8 1 0 0.0 0.00 1.0e+00 Plxnc1
Reaction time false alarm rate 63.4 1 1 2.4 0.00 1.0e+00 NA
Reaction time premature initiation rate 32.1 1 1 2.4 0.00 1.0e+00 NA
Reaction time premature initiations 19.0 4 1 2.4 0.98 6.4e-04 Nln Sgtb Erbin NA
Std. dev. reaction times 19.3 2 1 2.4 0.00 1.0e+00 Rps10 NA
Reaction time trials AUC 15.6 1 0 0.0 0.00 1.0e+00 NA
Social responses 74.3 1 1 2.4 0.00 1.0e+00 NA
Cocaine response after cond. corrected 78.0 1 1 2.4 0.00 1.0e+00 NA
Cocaine response after cond. not corrected 102.3 1 1 2.4 0.00 1.0e+00 NA
Cocaine response before conditioning 20.7 2 1 2.4 0.00 1.0e+00 NA NA
Saline control response 50.6 1 1 2.4 0.00 1.0e+00 NA
Condit. Reinf. active minus inactive responses 46.4 1 1 2.4 0.00 1.0e+00 NA
Condit. Reinf. active-inactive response ratio 68.7 1 1 2.4 0.00 1.0e+00 NA
Condit. Reinf. active responses 12.7 12 0 0.0 1.00 7.0e-19 Numa1 Atg16l2 Pde2a Art2b Folr2 Lrrc51 Il18bp Rnf121 Trpc2 Pgap2 NA NA
Condit. Reinf. inactive responses 20.6 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. lever presses 14.3 13 0 0.0 1.00 3.8e-16 Numa1 Atg16l2 Pde2a Art2b Folr2 Lrrc51 Il18bp Rnf121 Trpc2 Pgap2 Trim68 NA NA
Condit. Reinf. lever reinforcers received 12.8 12 0 0.0 1.00 8.0e-18 Numa1 Atg16l2 Pde2a Art2b Folr2 Lrrc51 Il18bp Rnf121 Trpc2 Pgap2 NA NA
Pavlov. Cond. lever latency 17.3 12 1 2.4 -0.15 6.0e-01 Numa1 Atg16l2 Pde2a Folr2 Lrrc51 Il18bp Rnf121 Trpc2 Pgap2 NA NA NA
Pavlov. Cond. magazine entry latency 104.9 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. change in total contacts 38.4 7 1 2.4 -0.48 2.0e-01 Numa1 Pde2a Lrrc51 Rnf121 Pgap2 NA NA
Pavlov. Cond. index score 62.2 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. latency score 67.1 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. lever contacts 16.0 12 1 2.4 0.44 1.3e-01 Numa1 Atg16l2 Pde2a Folr2 Lrrc51 Il18bp Rnf121 Trpc2 Pgap2 NA NA NA
Pavlov. Cond. magazine entry number 150.0 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. intertrial magazine entries 63.9 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. lever-magazine prob. diff. 55.1 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. response bias 16.6 12 1 2.4 0.32 2.8e-01 Numa1 Atg16l2 Pde2a Folr2 Lrrc51 Il18bp Rnf121 Trpc2 Pgap2 NA NA NA
Conditioned reinforcement - actives 18.5 1 0 0.0 0.00 1.0e+00 NA
Intermittent access intake day 1-15 change 61.5 1 1 2.4 0.00 1.0e+00 NA
Intermittent access intake escalation 82.5 1 1 2.4 0.00 1.0e+00 NA
Intermittent access intake escalation 2 35.3 2 2 4.9 0.00 1.0e+00 Snx16 NA
Intermitt. access day 1 inactive lever presses 30.6 1 1 2.4 0.00 1.0e+00 NA
Intermittent access day 1 total infusions 52.9 1 1 2.4 0.00 1.0e+00 NA
Intermittent access day 1 locomotion 27.1 1 1 2.4 0.00 1.0e+00 NA
Intermittent access standard deviation 19.8 1 0 0.0 0.00 1.0e+00 Snx16
Cocaine induced anxiety 14.0 1 0 0.0 0.00 1.0e+00 Snx16
Post-drug Anxiety 26.4 2 1 2.4 0.00 1.0e+00 Snx16 NA
Progressive ratio test 1 active lever presses 15.3 1 0 0.0 0.00 1.0e+00 Fgd6
Progressive ratio test 2 breakpoint 38.7 1 1 2.4 0.00 1.0e+00 NA
Short access day 10 total inactive lever presses 14.7 1 0 0.0 0.00 1.0e+00 Socs2
Short access day 10 total infusions 24.0 1 1 2.4 0.00 1.0e+00 NA
Short access day 1 locomotion 17.2 1 0 0.0 0.00 1.0e+00 NA
Compulsive drug intake 45.4 1 1 2.4 0.00 1.0e+00 NA
One hour access (shock baseline) 14.4 2 0 0.0 0.00 1.0e+00 Plxnc1 Cradd
Context. condit. distance diff. score 149.8 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, session 1 117.8 1 1 2.4 0.00 1.0e+00 NA
Locomotion distance, session 1 374.7 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, session 2 82.2 1 1 2.4 0.00 1.0e+00 NA
Locomotion distance, session 2 776.0 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, session 3 116.1 1 1 2.4 0.00 1.0e+00 NA
Locomotion distance, session 3 82.4 1 1 2.4 0.00 1.0e+00 NA
Stereotopy head waving duration, day 3 25.6 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, session 7 66.3 1 1 2.4 0.00 1.0e+00 NA
Locomotion distance, session 7 31.8 1 1 2.4 0.00 1.0e+00 NA
Stereotopy head waving bouts, day 7 42.6 1 1 2.4 0.00 1.0e+00 NA
Stereotopy head waving duration, day 7 63.4 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, session 8 13.7 1 0 0.0 0.00 1.0e+00 Clip3
Locomotion distance, session 8 102.8 1 1 2.4 0.00 1.0e+00 NA
Degree of sensitization distance 140.6 1 1 2.4 0.00 1.0e+00 NA
Degree of sensitization stereotypy 37.5 1 1 2.4 0.00 1.0e+00 NA
Condit. Reinf. active-inactive response ratio 65.1 1 1 2.4 0.00 1.0e+00 NA
Condit. Reinf. active responses 20.0 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. inactive responses 17.2 1 0 0.0 0.00 1.0e+00 NA
Incentive salience index mean 15.6 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. lever presses 35.1 1 1 2.4 0.00 1.0e+00 NA
Time in novel zone, hab. session 1 17.4 1 0 0.0 0.00 1.0e+00 NA
Total zone transitions, hab. session 1 415.6 1 1 2.4 0.00 1.0e+00 NA
Total locomotion distance, hab. session 1 171.4 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, hab. session 1 218.6 1 1 2.4 0.00 1.0e+00 NA
Time in familiar zone, hab. session 2 48.9 1 1 2.4 0.00 1.0e+00 NA
Time in novel zone, hab. session 2 58.4 1 1 2.4 0.00 1.0e+00 NA
Total zone transitions, hab. session 2 256.1 1 1 2.4 0.00 1.0e+00 NA
Total locomotion distance, hab. session 2 133.1 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, hab. session 2 139.4 1 1 2.4 0.00 1.0e+00 NA
Total zone transitions, NPP test 228.8 1 1 2.4 0.00 1.0e+00 NA
Total locomotion distance, NPP test 163.4 1 1 2.4 0.00 1.0e+00 NA
Locomotion velocity, NPP test 195.9 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry latency 56.4 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. change in total contacts 40.1 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. index score 51.9 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. latency score 16.6 1 0 0.0 0.00 1.0e+00 NA
Pavlov. Cond. lever contacts 16.1 1 0 0.0 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry number 61.6 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. lever-magazine prob. diff. 50.5 1 1 2.4 0.00 1.0e+00 NA
Pavlov. Cond. response bias 52.4 1 1 2.4 0.00 1.0e+00 NA
Bone: apparent density 20.6 2 1 2.4 0.00 1.0e+00 Snapc2 NA
Bone surface 16.4 5 1 2.4 0.98 3.7e-04 Snapc2 Elavl1 Lrrc8e NA Zfp958
Bone volume 20.8 3 1 2.4 1.00 1.1e-03 Snapc2 Rftn2 NA
Bone: connectivity density 11.2 5 0 0.0 1.00 1.2e-08 Evi5l Snapc2 Elavl1 Lrrc8e Zfp958
Bone: cortical porosity 109.3 1 1 2.4 0.00 1.0e+00 NA
Bone: cortical porosity 91.2 1 1 2.4 0.00 1.0e+00 NA
Bone: cortical thickness 17.9 1 0 0.0 0.00 1.0e+00 NA
Bone: elastic displacement 28.2 1 1 2.4 0.00 1.0e+00 NA
Bone: endosteal estimation 8.5 24 1 2.4 0.98 8.1e-42 RT1-S3 RT1-N3 Gnl1 Abcf1 Prr3 NA RT1-T24-1 Ilrun RT1-CE11 RT1-M6-2 RT1-T24-4 NA AABR07044397.1 Ddr1 NA Nudt3 NA NA RT1-CE16 RT1-CE15 NA RT1-CE14 NA NA
Bone: final force 39.5 1 1 2.4 0.00 1.0e+00 NA
Bone: final moment 31.9 1 1 2.4 0.00 1.0e+00 NA
Bone: marrow area 8.5 24 1 2.4 0.98 4.0e-38 RT1-S3 RT1-N3 Gnl1 Abcf1 Prr3 NA RT1-T24-1 Ilrun RT1-CE11 RT1-M6-2 RT1-T24-4 NA AABR07044397.1 Ddr1 NA Nudt3 NA NA RT1-CE16 RT1-CE15 NA RT1-CE14 NA NA
Bone: maximum force 42.0 1 1 2.4 0.00 1.0e+00 NA
Bone: maximum moment 29.5 1 1 2.4 0.00 1.0e+00 NA
Bone: minimum diameter 57.3 1 1 2.4 0.00 1.0e+00 NA
Bone: periosteal estimation 10.0 1 0 0.0 0.00 1.0e+00 NA
Bone: post-yield work 82.8 1 1 2.4 0.00 1.0e+00 NA
Bone: stiffness 90.4 1 1 2.4 0.00 1.0e+00 NA
Bone: tissue strength 81.0 1 1 2.4 0.00 1.0e+00 NA
Bone: trabecular number 39.4 1 1 2.4 0.00 1.0e+00 NA
Bone: trabecular thickness 13.8 1 0 0.0 0.00 1.0e+00 NA
Bone: trabecular tissue density 43.1 1 1 2.4 0.00 1.0e+00 NA
Distance traveled before self-admin 17.0 1 0 0.0 0.00 1.0e+00 Snx16
Delta time in open arm before/after self-admin 40.2 1 1 2.4 0.00 1.0e+00 NA
Time in closed arm before self-admin 50.0 1 1 2.4 0.00 1.0e+00 NA
Time in closed arm after self-admin 40.2 1 1 2.4 0.00 1.0e+00 NA
Time in open arm after self-admin 31.3 1 1 2.4 0.00 1.0e+00 NA
Time to tail flick, test, before self-admin 20.6 1 0 0.0 0.00 1.0e+00 Snx16
Delta time to tail flick, test, before/after SA 20.0 1 0 0.0 0.00 1.0e+00 NA
Time >=10cm from walls, locomotor time 1 19.5 1 0 0.0 0.00 1.0e+00 NA
Time >=10cm from walls, locomotor time 2 27.2 1 1 2.4 0.00 1.0e+00 NA
Weight adjusted by age 37.6 2 2 4.9 0.00 1.0e+00 Snx16 NA
Seeking ratio, delayed vs. immediate footshock 22.6 1 1 2.4 0.00 1.0e+00 Snx16
Food seeking constrained by brief footshock 16.7 1 0 0.0 0.00 1.0e+00 Snx16
Run reversals in cocaine runway, males 39.3 1 1 2.4 0.00 1.0e+00 NA
Latency to leave start box in cocaine runway 18.8 1 0 0.0 0.00 1.0e+00 NA
Cd content in liver 140.5 1 1 2.4 0.00 1.0e+00 NA
Co content in liver 83.2 1 1 2.4 0.00 1.0e+00 NA
Cu content in liver 14.2 2 0 0.0 0.00 1.0e+00 Hoxb9 NA
K content in liver 62.6 1 1 2.4 0.00 1.0e+00 NA
Mn content in liver 130.2 1 1 2.4 0.00 1.0e+00 NA
Rb content in liver 31.4 1 1 2.4 0.00 1.0e+00 NA
Se content in liver 47.0 1 1 2.4 0.00 1.0e+00 NA
Zn content in liver 46.0 1 1 2.4 0.00 1.0e+00 NA

chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.

Associations by panel

tissue modality # hits % hits/tests avg chisq
Adipose alternative polyA 14 0.66 3.2
Adipose alternative TSS 7 0.43 3.1
Adipose gene expression 42 0.51 2.9
Adipose isoform ratio 11 0.39 2.9
Adipose intron excision ratio 13 0.45 3.3
Adipose mRNA stability 17 0.49 3.0
BLA alternative polyA 7 0.58 2.9
BLA alternative TSS 1 0.12 3.1
BLA gene expression 36 0.59 3.0
BLA isoform ratio 7 0.40 3.2
BLA intron excision ratio 21 0.70 3.2
BLA mRNA stability 11 0.54 3.1
Brain alternative polyA 9 0.45 2.9
Brain alternative TSS 6 0.35 3.1
Brain gene expression 44 0.49 2.9
Brain isoform ratio 8 0.25 3.0
Brain intron excision ratio 30 0.55 3.3
Brain mRNA stability 15 0.34 2.8
Eye alternative polyA 2 1.12 3.0
Eye alternative TSS 2 0.83 2.9
Eye gene expression 7 0.62 2.9
Eye isoform ratio 2 0.56 3.3
Eye intron excision ratio 7 1.14 3.6
Eye mRNA stability 1 0.43 3.3
IL alternative polyA 1 0.16 3.2
IL alternative TSS 2 0.69 3.5
IL gene expression 12 0.33 3.0
IL isoform ratio 7 0.89 3.6
IL intron excision ratio 4 0.41 3.0
IL mRNA stability 4 0.36 2.9
LHb alternative polyA 2 0.35 3.5
LHb alternative TSS 0 0.00 2.6
LHb gene expression 12 0.37 2.9
LHb isoform ratio 3 0.40 3.1
LHb intron excision ratio 2 0.19 3.0
LHb mRNA stability 3 0.29 2.9
Liver alternative polyA 6 0.40 3.0
Liver alternative TSS 5 0.33 2.8
Liver gene expression 41 0.57 2.9
Liver isoform ratio 5 0.21 2.9
Liver intron excision ratio 16 0.37 3.0
Liver mRNA stability 12 0.49 2.9
NAcc alternative polyA 3 0.23 3.1
NAcc alternative TSS 3 0.32 3.2
NAcc gene expression 39 0.62 3.1
NAcc isoform ratio 13 0.69 3.3
NAcc intron excision ratio 9 0.29 3.2
NAcc mRNA stability 12 0.53 2.9
OFC alternative polyA 0 0.00 2.8
OFC alternative TSS 2 0.63 3.4
OFC gene expression 19 0.51 2.9
OFC isoform ratio 5 0.61 3.3
OFC intron excision ratio 5 0.50 3.4
OFC mRNA stability 2 0.19 2.9
PL alternative polyA 4 0.28 2.9
PL alternative TSS 2 0.17 3.5
PL gene expression 32 0.43 2.9
PL isoform ratio 7 0.32 3.5
PL intron excision ratio 22 0.61 3.3
PL mRNA stability 10 0.34 2.9

avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.