Hub : Genes

Sf3b2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Sf3b2 0.03 0.02 3.3e-03 0.01 0.02 0.01 0.01 1.7e-02 3.0e-03 1.5e-02 1.1e-02
2 NAcc gene expression Sf3b2 0.04 0.03 6.8e-05 0.02 0.03 0.03 0.03 7.2e-04 4.9e-05 5.5e-05 6.3e-05
3 NAcc mRNA stability Sf3b2 0.02 0.01 6.5e-03 0 0 0 0 3.4e-01 5.3e-02 1.9e-01 2.8e-01
4 pVTA gene expression Sf3b2 0.04 0.03 4.2e-03 0.01 0.02 0.02 0.01 3.0e-02 7.2e-03 6.1e-03 2.0e-02
5 IL gene expression Sf3b2 0.18 0.12 2.0e-03 0.04 0.04 0.02 0.06 3.5e-02 3.1e-02 1.1e-01 1.3e-02
6 Adipose gene expression Sf3b2 0.05 0.03 8.3e-05 0.04 0.03 0.04 0.04 4.1e-05 5.1e-04 7.6e-05 8.5e-05
7 Adipose mRNA stability Sf3b2 0.05 0.03 3.2e-05 0.04 0.03 0.03 0.03 6.8e-05 5.6e-04 6.7e-04 2.8e-04
8 PL mRNA stability Sf3b2 0.04 0.03 2.5e-03 0.04 0.03 0.03 0.03 9.4e-05 6.1e-04 1.8e-04 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density1.01.86.9-0.3-0.2-2.0-0.20.9-1.21.12.6
Area under the delay curve0.60.91.50.70.7-0.5-0.91.1-1.21.21.1
BMI with tail1.65.519.7-1.3-1.1-4.41.00.5-1.11.14.2
BMI without tail0.52.69.6-0.8-0.6-2.90.20.6-0.91.03.1
Body weight1.56.717.1-3.0-2.9-4.12.4-1.81.4-1.22.6
Weight adjusted by age0.72.23.2-1.7-1.7-1.01.8-1.61.5-1.50.1
Bone surface2.65.112.4-2.5-2.5-3.52.4-1.10.7-0.72.8
Bone volume1.02.06.2-1.3-1.2-2.51.0-0.1-0.10.12.3
Breakpoint value in progressive ratio session1.83.24.7-2.2-2.1-2.02.1-1.61.4-1.41.1
Number of licking bursts0.20.51.6-0.8-0.7-0.71.3-0.50.5-0.50.4
Context. condit. distance diff. score1.72.13.61.71.71.3-1.91.4-1.31.3-0.4
Locomotion velocity, session 10.10.10.40.00.00.30.3-0.40.4-0.4-0.7
Locomotion distance, session 10.60.72.7-0.2-0.1-1.50.00.4-0.60.61.6
Locomotion velocity, session 21.51.84.1-1.5-1.5-2.01.2-1.20.9-0.91.1
Locomotion distance, session 20.50.72.5-0.5-0.4-1.6-0.4-0.1-0.20.21.4
Locomotion velocity, session 30.40.50.90.60.7-0.3-1.00.7-0.80.80.6
Locomotion distance, session 30.00.00.10.10.10.0-0.30.0-0.10.10.1
Stereotopy head waving bouts, day 31.72.15.01.41.40.2-2.21.5-1.61.60.7
Stereotopy head waving duration, day 31.61.93.41.41.40.5-1.81.6-1.61.60.6
Locomotion velocity, session 71.01.01.50.91.0-0.5-1.01.1-1.21.21.1
Locomotion distance, session 70.30.30.70.30.4-0.6-0.60.5-0.70.60.8
Stereotopy head waving bouts, day 70.20.30.50.20.2-0.4-0.10.7-0.60.60.7
Stereotopy head waving duration, day 70.50.61.8-0.7-0.6-1.40.70.1-0.20.21.3
Locomotion velocity, session 80.60.71.2-1.1-1.1-0.70.6-1.00.9-0.90.1
Locomotion distance, session 80.50.71.90.80.90.0-1.40.8-0.80.80.3
Degree of sensitization distance0.30.40.90.30.3-0.6-0.40.6-0.70.70.9
Degree of sensitization stereotypy0.40.41.0-0.7-0.7-0.91.0-0.30.3-0.30.5
Conditioned locomotion1.31.52.0-1.4-1.4-1.01.3-1.41.2-1.30.1
Cocaine response after cond. corrected0.71.01.71.31.31.2-1.20.8-0.70.7-0.7
Cocaine response after cond. not corrected0.50.71.21.11.10.9-0.80.7-0.60.7-0.5
Cocaine response before conditioning0.70.81.7-1.1-1.1-0.91.3-0.70.6-0.60.5
Saline control response2.33.24.9-2.2-2.2-2.21.8-1.61.3-1.31.3
Bone: connectivity density1.82.89.1-1.4-1.3-2.91.10.0-0.40.43.0
Bone: cortical apparent density0.20.40.6-0.5-0.50.00.7-0.60.7-0.7-0.6
Bone: cortical area0.91.52.1-1.4-1.3-0.81.2-1.51.4-1.4-0.2
Bone: cortical porosity0.30.31.2-0.0-0.1-0.8-0.50.4-0.60.61.1
Bone: cortical porosity0.30.41.3-0.4-0.4-1.0-0.30.1-0.30.31.1
Bone: cortical thickness4.06.610.4-2.8-2.8-1.22.5-3.23.0-3.0-0.8
Bone: cortical thickness0.81.01.9-1.0-1.1-0.20.9-1.41.2-1.2-0.4
Bone: cortical tissue density0.30.50.8-0.7-0.6-0.10.8-0.80.9-0.9-0.6
Condit. Reinf. active minus inactive responses0.20.20.6-0.4-0.3-0.80.5-0.20.1-0.20.6
Condit. Reinf. active-inactive response ratio0.10.10.4-0.2-0.1-0.30.7-0.10.1-0.10.3
Condit. Reinf. active responses0.10.10.5-0.3-0.2-0.70.4-0.20.2-0.20.4
Condit. Reinf. inactive responses0.10.10.20.20.3-0.3-0.50.3-0.20.20.2
Incentive salience index mean0.30.31.4-0.5-0.4-1.20.4-0.20.1-0.10.8
Condit. Reinf. lever presses0.40.61.1-0.8-0.7-1.00.8-0.70.7-0.70.2
Condit. Reinf. active minus inactive responses0.10.20.40.20.2-0.1-0.40.6-0.50.50.5
Condit. Reinf. active-inactive response ratio0.20.40.70.70.70.5-0.60.8-0.60.6-0.1
Condit. Reinf. active responses0.40.62.2-0.1-0.2-0.9-0.40.7-0.80.81.5
Condit. Reinf. inactive responses0.71.03.8-0.4-0.4-1.4-0.30.5-0.90.92.0
Condit. Reinf. lever presses1.21.83.6-1.8-1.7-1.91.0-0.90.7-0.71.3
Condit. Reinf. lever reinforcers received0.40.62.2-0.5-0.5-1.1-0.20.4-0.50.51.5
Conditioned reinforcement - actives0.10.20.3-0.4-0.40.40.4-0.40.5-0.6-0.5
Conditioned reinforcement - inactives0.61.73.51.61.51.9-1.01.3-1.01.0-0.9
Conditioned locomotion4.26.211.02.92.83.3-2.72.1-1.81.7-2.0
Patch foraging indifference point 0 sec0.00.10.30.30.3-0.10.00.5-0.40.60.5
Patch foraging indifference point AUC1.22.84.3-2.1-2.1-1.31.8-1.81.6-1.8-0.1
Delay disc. indifference point, 0s delay2.02.24.51.41.5-0.0-2.11.6-1.81.80.8
Delay disc. indifference point, 16s delay0.50.81.30.91.00.3-0.61.1-1.11.10.4
Delay disc. indifference point, 2s delay0.40.40.60.60.60.0-0.80.7-0.80.80.4
Delay disc. indifference point, 24s delay0.00.00.10.30.30.4-0.20.0-0.10.1-0.1
Delay disc. indifference point, 4s delay1.01.01.60.80.9-0.2-1.31.1-1.31.30.9
Delay disc. indifference point, 8s delay0.40.71.00.60.6-0.3-1.00.9-1.01.00.9
Indifference point function ln k2.98.614.73.63.63.1-3.82.5-2.32.3-1.3
Indifference point function log k2.98.614.73.63.63.1-3.82.5-2.32.3-1.3
Patch foraging total patch changes 0 sec0.00.00.00.10.00.10.10.1-0.10.10.1
Patch foraging total patch changes 12 sec2.83.76.6-2.4-2.4-2.62.0-1.61.2-1.31.4
Patch foraging total patch changes 18 sec0.20.61.3-0.8-0.8-1.11.0-0.40.4-0.30.8
Patch foraging total patch changes 24 sec0.62.13.4-1.8-1.8-1.11.6-1.61.4-1.50.2
Patch foraging total patch changes 6 sec0.71.22.4-1.2-1.2-1.61.2-0.70.5-0.51.2
Patch foraging time to switch 0 sec0.62.37.5-1.2-1.0-2.71.60.1-0.00.32.5
Patch foraging water rate 0 sec1.14.112.92.01.93.6-1.90.6-0.30.2-2.9
Patch foraging water rate 12 sec2.39.121.13.43.24.6-3.71.7-1.51.4-2.9
Patch foraging water rate 18 sec1.22.85.72.01.92.4-1.91.1-1.11.0-1.3
Patch foraging water rate 24 sec2.94.110.92.22.13.3-1.91.0-0.90.6-2.5
Patch foraging water rate 6 sec2.84.110.82.12.03.3-2.50.6-0.40.4-2.5
Seeking ratio, delayed vs. immediate footshock0.40.61.10.50.6-0.5-0.11.0-1.01.11.0
Distance traveled before self-admin0.20.41.2-0.6-0.6-1.10.4-0.20.2-0.20.8
Distance traveled after self-admin0.10.20.3-0.6-0.6-0.50.4-0.30.4-0.40.1
Extensor digitorum longus weight5.421.731.7-5.6-5.4-5.15.0-4.84.2-4.31.6
Bone: elastic displacement0.81.03.40.40.41.7-0.2-0.50.7-0.7-1.9
Bone: elastic work1.41.83.2-1.4-1.3-0.41.1-1.81.7-1.7-0.7
Bone: endosteal estimation1.33.14.41.81.80.1-2.02.1-2.12.11.1
Bone: endosteal perimeter1.43.45.51.81.90.2-1.82.3-2.32.31.2
Epididymis fat weight1.57.811.53.43.33.3-2.92.7-2.32.3-1.7
Delta time in closed arm before/after self-admin0.10.10.2-0.2-0.2-0.4-0.4-0.30.1-0.10.4
Delta time in open arm before/after self-admin0.30.40.9-0.7-0.7-0.20.9-0.50.6-0.6-0.2
Diff in mean of infusions in LGA sessions0.50.91.4-1.1-1.1-0.61.2-1.01.0-1.0-0.0
Delay discount exponential model param0.50.61.1-0.5-0.60.40.7-0.91.0-1.0-1.0
Extinction: sum of active levers before priming1.32.04.7-1.6-1.5-2.21.6-0.90.7-0.71.6
Active lever presses in extinction session 63.43.56.7-2.1-2.1-1.42.6-1.91.8-1.80.2
Bone: final force1.42.33.7-1.9-1.9-1.91.3-1.51.3-1.30.9
Bone: final moment1.32.13.4-1.8-1.8-1.81.2-1.41.2-1.20.9
Food consumed during 24 hour testing period0.20.40.7-0.5-0.60.50.4-0.70.8-0.8-0.9
Glucose3.25.17.82.62.60.6-2.82.5-2.62.50.8
Heart weight2.94.77.12.12.2-0.2-2.12.5-2.62.72.0
Delay discount hyperbolic model param0.50.71.2-0.5-0.60.40.8-0.91.1-1.1-1.0
Intermittent access intake day 1-15 change0.10.82.60.90.91.6-0.40.4-0.10.0-1.3
Intermittent access intake escalation0.10.72.40.70.61.5-0.00.10.2-0.2-1.4
Intermittent access intake escalation 20.50.82.60.70.71.6-0.20.20.2-0.2-1.6
Intermitt. access day 1 inactive lever presses0.00.10.40.20.20.40.20.10.0-0.0-0.6
Intermitt. access day 15 inactive lever presses0.20.91.51.21.21.0-0.41.2-0.90.9-0.5
Intermitt. access escalation Index1.54.68.82.42.41.5-3.02.2-2.12.2-0.3
Intermittent access day 1 total infusions1.95.79.52.32.30.3-2.13.0-3.13.01.6
Intermittent access day 15 total infusions1.64.06.02.42.42.0-1.72.3-2.02.0-0.4
Intermittent access terminal intake (last 3 days)2.23.85.72.32.31.5-1.62.4-2.22.1-0.0
Intermittent access total infusions3.33.96.12.12.10.9-1.82.5-2.42.40.9
Intermittent access day 1 locomotion1.93.55.91.91.90.4-1.42.4-2.42.41.0
Intermittent access day 15 total locomotion0.93.34.82.22.21.6-1.32.2-2.01.9-0.1
Intermittent access total locomotion5.36.49.82.92.91.6-2.13.1-3.02.90.3
Intermittent access standard deviation0.20.82.41.11.11.5-0.70.7-0.50.4-0.8
Left kidney weight0.53.77.82.12.21.5-2.82.0-1.61.8-0.7
Right kidney weight0.21.52.71.21.21.6-1.70.9-0.60.7-1.4
Cocaine induced anxiety0.00.10.1-0.3-0.3-0.20.4-0.20.3-0.2-0.1
Post-drug Anxiety0.60.61.1-1.0-1.1-0.70.6-0.80.9-0.80.0
Baseline Anxiety0.20.30.4-0.6-0.6-0.3-0.5-0.70.6-0.6-0.2
Tail length0.31.52.7-1.4-1.4-0.30.8-1.51.6-1.4-0.7
Length with tail1.56.59.6-3.1-3.1-1.82.5-2.92.9-2.7-0.4
Length without tail1.15.67.9-2.8-2.8-1.62.5-2.82.6-2.5-0.3
Times rat made contact with spout0.30.41.1-0.5-0.5-1.00.6-0.2-0.00.01.1
Lifetime Intake2.73.45.21.91.90.6-1.82.2-2.32.21.0
Liver weight, left0.71.22.11.21.21.4-1.30.8-0.80.6-1.2
Liver weight, right1.62.84.52.12.11.9-2.11.3-1.31.3-0.9
Locomotor activity1.11.74.71.51.42.2-1.50.6-0.00.4-1.5
Locomotor testing distance1.02.56.01.81.72.5-2.00.8-0.20.6-1.6
Locomotor testing rearing0.83.05.62.12.01.9-2.41.6-1.11.5-0.5
Locomotion in novel chamber3.54.77.02.62.62.4-2.22.0-1.81.7-1.6
Locomotion in novel chamber post-restriction0.92.74.02.02.01.8-1.61.6-1.41.4-1.0
Fecal boli incidents, locomotor time 10.10.20.7-0.3-0.30.10.9-0.20.3-0.3-0.5
Change in fecal boli incidents, locomotor task0.40.41.30.40.4-0.3-0.60.6-0.70.71.1
Time >=10cm from walls, locomotor time 11.31.63.11.01.1-0.1-0.41.8-1.71.71.2
Bouts of movement, locomotor time 11.41.94.4-1.5-1.5-0.92.1-1.21.3-1.3-0.1
Total resting periods, locomotor time 11.11.23.4-1.2-1.2-0.81.8-0.91.0-1.00.0
Rest time, locomotor task time 10.71.12.61.21.11.6-1.10.6-0.40.4-1.4
Distance moved, locomotor task time 10.20.72.8-0.00.0-1.1-0.30.5-0.70.71.7
Vertical activity count, locomotor time 10.10.71.01.01.00.7-0.90.9-0.90.90.2
Time >=10cm from walls, locomotor time 20.00.00.1-0.2-0.1-0.10.30.00.1-0.1-0.0
Bouts of movement, locomotor time 20.20.51.3-0.8-0.8-0.91.1-0.50.4-0.40.5
Total resting periods, locomotor time 20.10.20.5-0.5-0.4-0.70.7-0.10.0-0.00.5
Rest time, locomotor task time 21.42.44.11.81.81.5-2.01.5-1.31.3-0.8
Distance moved, locomotor task time 21.11.51.9-1.4-1.4-1.01.2-1.41.3-1.30.5
Vertical activity count, locomotor time 20.30.71.2-0.5-0.50.70.4-1.01.1-1.1-0.8
Light reinforcement 10.00.20.30.40.30.5-0.50.3-0.50.3-0.1
Light reinforcement 20.20.41.30.70.71.2-0.30.4-0.30.3-0.8
Bone: marrow area1.43.44.81.91.90.2-2.12.2-2.22.21.1
Bone: maximum diameter0.20.30.6-0.6-0.7-0.20.8-0.60.6-0.6-0.3
Bone: maximum force1.83.58.1-2.2-2.1-2.82.0-1.31.0-1.11.8
Bone: maximum moment1.73.27.5-2.1-2.0-2.71.8-1.20.9-1.01.7
Mean time between licks in bursts0.00.10.3-0.4-0.5-0.30.2-0.50.3-0.30.2
Mean num. licks in bursts0.20.51.40.80.80.3-1.20.7-0.70.80.3
Cd content in liver0.70.81.21.11.11.0-0.31.1-0.90.9-0.3
Co content in liver1.21.44.11.00.92.0-1.2-0.00.2-0.2-1.9
Cu content in liver0.20.20.60.20.2-0.5-0.30.3-0.50.50.7
Fe content in liver0.30.30.5-0.6-0.6-0.00.6-0.70.7-0.7-0.3
K content in liver0.30.31.2-0.4-0.4-1.10.5-0.1-0.10.11.0
Mg content in liver0.60.61.00.80.90.1-0.70.9-1.01.00.6
Mn content in liver3.23.66.3-2.3-2.3-1.82.5-1.81.6-1.70.6
Na content in liver1.11.22.0-1.0-1.00.11.1-1.31.4-1.4-1.0
Rb content in liver2.22.63.41.81.80.9-1.91.8-1.81.80.5
Se content in liver0.10.10.10.20.20.2-0.20.4-0.30.30.1
Sr content in liver3.22.85.2-1.8-1.8-0.82.3-1.81.8-1.8-0.5
Zn content in liver0.10.10.4-0.4-0.3-0.70.2-0.30.1-0.10.5
Bone: minimum diameter1.63.14.71.61.7-0.4-1.62.1-2.22.21.6
Time in familiar zone, hab. session 10.30.30.50.50.6-0.0-0.30.7-0.70.70.3
Time in novel zone, hab. session 10.20.20.80.30.30.9-0.6-0.10.1-0.0-0.6
Total zone transitions, hab. session 10.50.71.5-0.9-0.9-1.21.0-0.70.6-0.60.6
Total locomotion distance, hab. session 10.20.40.80.80.90.2-0.50.7-0.60.6-0.0
Locomotion velocity, hab. session 10.10.10.10.30.4-0.3-0.20.3-0.30.30.2
Time in familiar zone, hab. session 20.10.10.2-0.1-0.10.30.3-0.30.3-0.3-0.4
Time in novel zone, hab. session 20.30.30.80.10.1-0.6-0.60.5-0.50.50.9
Total zone transitions, hab. session 21.92.48.7-0.5-0.4-2.50.50.9-1.21.13.0
Total locomotion distance, hab. session 21.11.42.90.70.8-1.0-0.51.3-1.51.41.7
Locomotion velocity, hab. session 21.11.52.50.90.9-0.8-0.61.4-1.51.51.6
Novel to familiar place preference ratio0.60.82.0-1.0-1.0-1.11.4-0.50.5-0.60.6
Novelty place preference0.30.41.0-0.6-0.6-0.81.0-0.20.2-0.20.5
Time in novel zone, NPP test0.20.20.5-0.5-0.5-0.70.7-0.00.0-0.00.6
Total zone transitions, NPP test1.11.64.9-1.4-1.3-2.20.9-0.60.3-0.41.7
Total locomotion distance, NPP test0.20.30.70.20.3-0.8-0.80.4-0.50.40.8
Locomotion velocity, NPP test0.10.20.60.00.1-0.8-0.50.3-0.30.30.7
Intraocular pressure0.50.93.10.60.51.80.10.20.4-0.2-1.7
Delta distance traveled before/after self-admin0.10.10.40.10.10.6-0.4-0.00.1-0.1-0.6
Delta ambulatory time before/after self-admin0.00.10.2-0.0-0.10.4-0.3-0.10.2-0.2-0.4
Parametrial fat weight3.17.311.13.23.22.2-3.32.9-2.52.6-0.6
Pavlov. Cond. lever latency0.10.20.60.40.40.8-0.30.3-0.20.2-0.4
Pavlov. Cond. magazine entry latency0.30.31.2-0.2-0.1-1.10.20.3-0.30.31.0
Pavlov. Cond. change in total contacts0.10.10.4-0.3-0.3-0.60.7-0.10.2-0.20.2
Pavlov. Cond. index score0.20.20.3-0.5-0.4-0.50.5-0.40.4-0.40.0
Pavlov. Cond. latency score0.10.10.3-0.2-0.2-0.50.2-0.20.1-0.10.2
Pavlov. Cond. lever contacts0.10.10.3-0.1-0.1-0.6-0.3-0.1-0.00.00.4
Pavlov. Cond. magazine entry number0.40.50.70.70.70.5-0.90.7-0.80.80.2
Pavlov. Cond. intertrial magazine entries0.20.20.60.30.20.8-0.10.00.2-0.2-0.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.6-0.5-0.80.6-0.50.5-0.50.2
Pavlov. Cond. response bias0.30.30.5-0.6-0.6-0.40.7-0.60.7-0.7-0.2
Pavlov. Cond. lever latency0.50.71.21.11.10.7-0.50.9-0.90.9-0.0
Pavlov. Cond. magazine entry latency2.63.67.8-2.3-2.2-2.81.8-1.41.1-1.11.8
Pavlov. Cond. change in total contacts0.71.73.3-1.7-1.6-1.81.3-0.80.8-0.81.1
Pavlov. Cond. index score1.52.34.4-1.9-1.9-2.11.3-1.21.1-1.11.2
Pavlov. Cond. latency score1.32.13.7-1.8-1.8-1.91.4-1.21.1-1.11.0
Pavlov. Cond. lever contacts0.40.61.2-1.1-1.1-0.80.6-0.80.8-0.80.2
Pavlov. Cond. magazine entry number4.76.110.73.13.03.3-2.62.0-1.71.7-1.9
Pavlov. Cond. intertrial magazine entries0.40.91.81.21.21.3-0.60.9-0.80.8-0.7
Pavlov. Cond. lever-magazine prob. diff.1.82.85.2-2.1-2.1-2.31.5-1.31.2-1.21.3
Pavlov. Cond. response bias1.31.83.4-1.8-1.7-1.81.0-1.00.9-0.91.1
Time in closed arm before self-admin0.20.30.50.60.60.2-0.00.7-0.70.70.2
Time in closed arm after self-admin0.10.10.20.50.50.2-0.30.2-0.30.3-0.1
Time in open arm before self-admin0.20.31.10.60.60.5-1.10.1-0.20.2-0.2
Time in open arm after self-admin0.00.00.0-0.2-0.2-0.00.0-0.20.2-0.2-0.1
Bone: periosteal estimation0.00.10.10.10.2-0.4-0.30.3-0.30.30.4
Bone: periosteal perimeter0.10.20.6-0.3-0.2-0.80.20.1-0.20.20.8
Bone: post-yield work2.23.812.10.10.2-2.90.51.6-1.91.83.5
Progressive ratio test 1 active lever presses0.10.20.40.40.40.1-0.20.6-0.60.50.6
Progressive ratio test 1 breakpoint0.10.20.30.30.30.1-0.10.5-0.50.50.6
Progressive ratio test 1 inactive lever presses0.00.10.10.10.10.10.20.3-0.30.30.3
Progressive ratio test 2 active lever presses1.21.72.61.41.41.1-1.11.6-1.51.50.2
Progressive ratio test 2 breakpoint1.21.52.31.41.31.1-1.01.5-1.41.40.1
Progressive ratio test 2 inactive lever presses2.27.19.73.13.12.5-2.53.1-2.82.8-0.6
Incentive Sensitization - Responses0.10.31.10.10.1-0.50.10.6-0.70.71.1
Incentive Sensitization - Breakpoint0.10.30.80.30.3-0.3-0.00.7-0.70.80.9
Sum of active levers in priming session hrs 5-65.14.87.0-2.1-2.10.22.6-2.32.6-2.6-1.9
Progressive ratio0.72.06.8-0.3-0.2-2.20.60.9-1.11.22.6
Food seeking constrained by brief footshock0.10.20.2-0.4-0.4-0.30.4-0.50.5-0.40.3
Seeking ratio, punishment vs. effort0.61.34.20.80.72.0-1.0-0.30.5-0.5-1.8
Retroperitoneal fat weight7.332.545.96.86.75.7-6.85.7-5.15.2-2.2
Reaction time number correct0.20.81.4-0.8-0.80.20.7-1.21.0-1.1-0.8
Reaction time mean minus median0.64.28.4-2.3-2.3-2.12.9-1.71.9-1.60.7
Reaction time mean minus median AUC0.53.06.4-1.9-1.8-1.22.5-1.72.0-1.7-0.0
Reaction time num false alarms0.20.40.90.50.50.8-0.8-0.2-0.2-0.2-0.9
Reaction time num false alarms AUC0.10.20.5-0.2-0.10.1-0.1-0.70.3-0.6-0.6
Reaction time trials correct on left0.20.81.4-0.8-0.80.20.7-1.21.0-1.1-0.8
Reaction time trials on left0.31.01.7-0.9-1.00.10.8-1.31.2-1.3-0.9
Reaction time mean0.10.10.6-0.3-0.2-0.30.80.00.4-0.10.0
Reaction time mean AUC0.00.10.7-0.2-0.1-0.30.80.20.2-0.00.1
Median of all reaction times0.10.10.40.40.40.2-0.00.7-0.30.50.1
Reaction time omissions1.62.63.8-1.8-1.8-1.51.9-1.61.8-1.50.2
Reaction time false alarm rate0.10.20.40.50.50.3-0.60.1-0.40.1-0.4
Reaction time premature initiation rate1.32.03.0-1.7-1.7-1.41.5-1.51.2-1.20.7
Reaction time premature initiations1.44.36.0-2.4-2.5-1.42.3-2.42.1-2.20.1
Std. dev. reaction times0.41.43.5-1.3-1.3-1.11.9-0.81.2-0.90.3
Reaction time trials completed0.31.01.7-0.9-1.00.10.8-1.31.2-1.3-0.9
Reaction time trials AUC0.20.71.2-0.7-0.70.20.6-1.11.0-1.1-0.8
Run reversals in cocaine runway, females0.60.73.0-0.00.1-1.2-0.00.3-0.70.71.7
Run reversals in cocaine runway, males1.11.23.8-0.0-0.11.50.0-1.01.1-1.2-1.9
Latency to leave start box in cocaine runway0.30.40.70.40.5-0.6-0.10.8-0.80.80.8
Latency to leave start box in cocaine runway, F0.20.30.50.40.4-0.5-0.20.6-0.60.60.7
Latency to leave start box in cocaine runway, M0.10.10.2-0.2-0.2-0.50.40.0-0.00.00.3
Std. dev. time between licks in bursts0.10.20.60.20.10.5-0.8-0.30.2-0.2-0.6
Total sessions with >9 infusions0.70.92.90.20.3-0.9-0.30.9-1.11.01.7
Short access day 1 total inactive lever presses1.32.53.81.81.81.3-1.91.8-1.61.7-0.2
Short access day 10 total inactive lever presses0.00.30.40.60.70.6-0.40.4-0.30.4-0.6
Short access day 1 total infusions1.42.84.31.71.70.5-1.91.9-2.12.00.7
Short access day 10 total infusions1.83.06.21.01.1-1.0-0.82.0-2.32.22.5
Short access total infusions1.41.93.31.01.0-0.5-1.21.6-1.81.81.7
Short access day 1 locomotion1.01.72.91.41.40.5-0.91.6-1.71.60.7
Short access day 10 total locomotion0.41.52.61.31.30.2-0.61.6-1.61.60.9
Short access total locomotion1.21.93.21.41.40.4-0.91.7-1.81.70.9
One hour access (0.3 mA shock)4.45.27.52.72.72.3-2.12.5-2.32.2-0.6
Compulsive drug intake1.11.73.0-1.4-1.4-0.70.6-1.71.6-1.6-0.3
One hour access (shock baseline)2.25.78.32.92.82.3-2.02.7-2.52.4-0.6
Social response proportion0.60.82.8-0.9-0.9-0.91.7-0.40.3-0.30.8
Social responses0.30.41.0-0.6-0.7-0.21.0-0.50.7-0.50.1
Social time0.30.40.8-0.7-0.7-0.20.9-0.70.7-0.7-0.2
Soleus weight3.08.813.23.63.63.6-3.52.5-2.02.1-2.0
Bone: stiffness1.32.36.3-1.7-1.6-2.51.5-0.70.4-0.41.9
Tibialis anterior weight9.030.943.7-6.6-6.5-4.46.1-6.25.8-5.80.1
Time to tail flick, vehicle, before self-admin0.20.20.8-0.1-0.1-0.70.40.1-0.20.20.9
Time to tail flick, vehicle, after self-admin0.51.04.0-0.10.0-1.6-0.00.6-0.80.82.0
Time to tail flick, test, before self-admin3.23.65.21.92.00.3-2.22.2-2.32.31.3
Time to tail flick, test, after self-admin0.10.10.6-0.3-0.30.00.8-0.00.1-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.40.41.7-0.3-0.2-1.00.30.3-0.40.41.3
Delta time to tail flick, test, before/after SA4.05.07.5-2.0-2.10.22.7-2.42.6-2.6-1.9
Tibia length1.43.85.4-2.2-2.2-0.92.3-2.02.2-2.2-0.7
Ambulatory time before self-admin0.10.41.1-0.6-0.6-1.00.8-0.20.2-0.20.7
Ambulatory time after self-admin0.20.30.60.50.4-0.1-0.40.8-0.60.60.2
Bone: tissue strength0.00.10.2-0.00.0-0.30.00.2-0.20.20.4
Total heroin consumption3.74.36.5-2.5-2.5-2.22.3-2.01.8-1.80.8
Bone: trabecular number0.91.66.1-0.7-0.7-2.10.40.5-0.80.82.5
Bone: trabecular spacing0.30.51.00.80.81.0-0.80.3-0.20.2-0.8
Bone: trabecular thickness0.81.11.90.80.8-0.3-0.71.3-1.41.41.3
Bone: trabecular tissue density2.13.78.02.12.12.8-2.31.1-0.70.7-2.2
Water consumed over 24 hours0.40.81.3-1.1-1.1-1.01.1-0.80.6-0.60.7
Number of responses in last shaping day0.10.10.50.10.00.3-0.70.0-0.10.1-0.3