Hub : Genes

Sf3b2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Sf3b2 0.04 0.03 7.3e-03 0.01 0.01 0.01 0.01 2.6e-02 1.2e-02 3.4e-02 5.5e-02
2 NAcc gene expression Sf3b2 0.04 0.03 8.2e-04 0.03 0.02 0.01 0.02 3.6e-04 2.6e-03 2.1e-02 1.2e-03
3 PL gene expression Sf3b2 0.04 0.03 7.3e-04 0.01 0.03 0.02 0.02 8.7e-03 7.0e-04 3.1e-03 1.9e-03
4 IL gene expression Sf3b2 0.2 0.11 5.8e-04 0.08 0.07 0.09 0.06 4.7e-03 8.9e-03 3.2e-03 1.3e-02
5 BLA mRNA stability Sf3b2 0.21 0.11 6.7e-09 0.11 0.13 0.12 0.11 1.4e-06 2.0e-07 1.0e-06 1.3e-06
6 pVTA mRNA stability Sf3b2 0.23 0.19 5.9e-04 0.07 0.04 0.06 0.07 4.1e-04 5.3e-03 1.0e-03 5.0e-04
7 Brain mRNA stability Sf3b2 0.18 0.07 0.0e+00 0.21 0.2 0.22 0.21 5.2e-19 1.9e-18 1.2e-20 1.8e-19
8 Adipose mRNA stability Sf3b2 0.04 0.03 2.8e-04 0.02 0.02 0.02 0.02 1.1e-03 3.1e-03 2.4e-03 2.2e-03
9 Adipose gene expression Sf3b2 0.05 0.03 9.3e-05 0.04 0.03 0.03 0.03 6.5e-05 4.8e-04 3.6e-04 1.3e-04
10 NAcc mRNA stability Sf3b2 0.12 0.07 1.7e-11 0.1 0.1 0.1 0.1 8.0e-12 8.8e-12 8.3e-12 1.5e-11
11 PL mRNA stability Sf3b2 0.16 0.08 4.7e-15 0.14 0.14 0.14 0.14 3.5e-15 4.9e-15 2.9e-15 1.4e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.02.5-0.90.80.00.2-0.91.31.50.7-1.11.1-1.6
Area under the delay curve0.91.02.00.1-0.40.8-0.4-1.01.31.21.0-1.21.2-1.4
BMI with tail1.03.113.8-3.72.9-1.52.1-0.40.50.81.2-0.70.7-1.1
BMI without tail0.51.04.1-2.01.3-0.61.1-0.30.40.41.0-0.80.8-0.7
Body weight2.18.721.2-4.64.3-3.64.02.5-2.3-1.9-1.71.7-1.71.8
Weight adjusted by age2.63.03.8-1.71.7-1.91.91.7-1.9-1.6-1.61.7-1.71.7
Bone surface1.32.38.0-2.62.8-2.11.90.9-0.40.0-1.20.6-0.6-0.0
Bone volume0.40.72.7-1.51.6-1.00.7-0.10.30.7-0.2-0.20.2-0.7
Breakpoint value in progressive ratio session2.93.24.8-2.12.2-2.21.91.6-1.7-1.5-1.61.7-1.71.5
Number of licking bursts0.20.30.4-0.60.6-0.60.50.4-0.4-0.3-0.40.6-0.60.4
Context. condit. distance diff. score1.82.22.91.5-1.71.7-1.6-1.41.31.11.4-1.61.6-1.2
Locomotion velocity, session 10.10.10.2-0.00.1-0.10.30.4-0.4-0.5-0.20.3-0.30.4
Locomotion distance, session 10.40.51.0-1.00.9-0.20.6-0.40.50.70.7-0.70.7-0.8
Locomotion velocity, session 21.61.84.7-2.22.0-1.61.91.0-1.1-0.8-0.50.9-0.90.8
Locomotion distance, session 20.30.51.8-1.31.1-0.61.10.1-0.00.20.5-0.30.3-0.2
Locomotion velocity, session 30.40.51.5-0.0-0.20.6-0.3-0.80.70.71.2-0.70.7-0.7
Locomotion distance, session 30.00.00.10.1-0.10.2-0.1-0.10.10.10.3-0.10.1-0.1
Stereotopy head waving bouts, day 31.31.62.00.6-1.11.3-0.9-1.31.41.31.4-1.41.4-1.4
Stereotopy head waving duration, day 31.41.72.11.0-1.31.4-1.3-1.41.51.41.2-1.31.3-1.4
Locomotion velocity, session 71.31.43.50.0-0.41.0-0.6-1.41.21.21.9-1.51.5-1.3
Locomotion distance, session 70.30.41.1-0.3-0.00.40.1-0.50.50.41.1-1.01.0-0.6
Stereotopy head waving bouts, day 70.50.61.20.5-0.50.6-1.0-0.90.91.10.6-0.60.6-0.9
Stereotopy head waving duration, day 70.20.31.0-1.00.9-0.60.4-0.10.30.5-0.10.2-0.2-0.4
Locomotion velocity, session 81.01.21.8-1.01.2-1.11.31.2-0.9-1.1-1.10.9-0.90.9
Locomotion distance, session 80.50.71.40.2-0.50.7-0.5-0.90.70.81.2-1.11.1-0.7
Degree of sensitization distance0.40.40.8-0.30.00.30.1-0.50.60.50.8-0.90.9-0.8
Degree of sensitization stereotypy0.10.10.4-0.70.7-0.60.10.1-0.10.1-0.20.3-0.30.0
Conditioned locomotion1.92.23.0-1.61.4-1.61.71.6-1.7-1.5-1.20.9-0.91.7
Cocaine response after cond. corrected1.11.22.01.2-1.41.4-1.0-0.90.90.81.2-1.11.1-0.8
Cocaine response after cond. not corrected0.91.01.61.1-1.31.3-1.0-0.91.00.81.0-0.90.9-0.9
Cocaine response before conditioning0.40.50.9-0.71.0-0.90.60.5-0.4-0.4-0.80.9-0.90.3
Saline control response2.43.16.2-2.42.5-2.12.31.7-1.1-1.1-1.71.2-1.20.8
Bone: connectivity density0.71.14.0-2.02.0-1.11.30.10.40.7-0.2-0.50.5-0.8
Bone: cortical apparent density0.30.30.5-0.70.6-0.60.70.6-0.6-0.6-0.40.4-0.40.6
Bone: cortical area1.01.62.3-1.11.3-1.41.11.2-1.5-1.3-0.81.2-1.21.5
Bone: cortical porosity0.20.30.5-0.40.20.10.1-0.40.60.70.4-0.70.7-0.7
Bone: cortical porosity0.20.20.7-0.90.6-0.40.60.10.20.3-0.2-0.20.2-0.4
Bone: cortical thickness4.87.89.7-2.52.5-2.82.92.9-3.1-3.1-2.12.8-2.83.0
Bone: cortical thickness1.82.13.3-1.11.0-1.21.61.6-1.6-1.8-1.01.6-1.61.6
Bone: cortical tissue density0.40.50.7-0.70.6-0.70.80.7-0.7-0.7-0.60.5-0.50.7
Condit. Reinf. active minus inactive responses0.10.10.3-0.50.5-0.30.3-0.0-0.10.10.1-0.30.30.0
Condit. Reinf. active-inactive response ratio0.00.00.1-0.10.2-0.10.0-0.1-0.00.10.0-0.30.3-0.0
Condit. Reinf. active responses0.10.10.3-0.50.4-0.30.2-0.1-0.20.00.4-0.40.40.2
Condit. Reinf. inactive responses0.10.10.5-0.2-0.00.1-0.1-0.40.00.20.7-0.50.5-0.1
Incentive salience index mean0.20.20.7-0.90.7-0.40.5-0.1-0.20.10.4-0.40.40.0
Condit. Reinf. lever presses0.20.30.8-0.90.7-0.70.60.3-0.8-0.50.10.2-0.20.7
Condit. Reinf. active minus inactive responses0.30.41.00.6-0.30.4-0.8-0.80.81.00.3-0.40.4-0.8
Condit. Reinf. active-inactive response ratio0.70.71.71.0-0.70.7-1.3-1.10.71.10.7-0.60.6-0.6
Condit. Reinf. active responses0.30.41.4-0.00.30.2-0.3-0.71.01.10.3-0.40.4-1.2
Condit. Reinf. inactive responses0.30.41.5-0.70.6-0.00.5-0.21.00.70.2-0.40.4-1.2
Condit. Reinf. lever presses1.31.84.3-1.72.1-1.81.51.1-0.9-0.7-1.21.2-1.20.7
Condit. Reinf. lever reinforcers received0.20.20.7-0.30.6-0.20.0-0.30.70.8-0.1-0.10.1-0.9
Conditioned reinforcement - actives0.10.10.40.6-0.30.2-0.5-0.00.1-0.0-0.20.2-0.20.1
Conditioned reinforcement - inactives3.74.19.13.0-2.62.3-2.8-1.91.51.71.2-1.51.5-1.2
Conditioned locomotion4.25.112.83.6-3.22.8-3.2-1.91.41.41.5-1.41.4-1.0
Patch foraging indifference point 0 sec0.10.20.30.3-0.20.3-0.5-0.40.50.60.3-0.40.4-0.5
Patch foraging indifference point AUC3.13.65.7-2.22.4-2.22.21.9-1.7-1.6-1.91.6-1.61.5
Delay disc. indifference point, 0s delay1.92.13.10.6-1.01.4-0.6-1.41.71.51.7-1.71.7-1.8
Delay disc. indifference point, 16s delay1.41.42.10.9-0.91.1-1.3-1.41.11.41.1-1.21.2-1.1
Delay disc. indifference point, 2s delay0.20.20.40.4-0.30.5-0.5-0.60.50.50.6-0.30.3-0.5
Delay disc. indifference point, 24s delay0.10.10.20.2-0.40.3-0.0-0.00.20.10.0-0.30.3-0.2
Delay disc. indifference point, 4s delay0.90.91.90.3-0.50.9-0.3-0.91.41.01.0-1.11.1-1.4
Delay disc. indifference point, 8s delay0.60.71.40.1-0.40.7-0.2-0.61.01.00.8-1.01.0-1.2
Indifference point function ln k5.78.014.33.5-3.83.5-3.2-2.72.22.02.8-2.32.3-1.9
Indifference point function log k5.78.014.33.5-3.83.5-3.2-2.72.22.02.8-2.32.3-1.9
Patch foraging total patch changes 0 sec0.00.00.00.2-0.20.1-0.20.00.10.10.0-0.10.1-0.1
Patch foraging total patch changes 12 sec3.14.08.7-2.82.9-2.42.61.8-1.4-1.3-1.51.4-1.41.1
Patch foraging total patch changes 18 sec0.20.31.1-1.01.0-0.70.70.3-0.1-0.0-0.20.2-0.2-0.0
Patch foraging total patch changes 24 sec2.32.83.9-1.82.0-1.92.01.8-1.4-1.5-1.81.4-1.41.3
Patch foraging total patch changes 6 sec0.50.82.3-1.51.5-1.11.30.7-0.4-0.3-0.50.3-0.30.2
Patch foraging time to switch 0 sec0.60.94.2-2.11.6-1.11.10.0-0.10.30.2-0.20.2-0.3
Patch foraging water rate 0 sec1.52.49.23.0-2.71.9-2.2-0.70.40.20.3-0.30.30.1
Patch foraging water rate 12 sec3.75.616.94.1-3.93.2-2.9-1.51.50.91.2-1.21.2-0.9
Patch foraging water rate 18 sec1.62.25.22.3-2.22.0-1.7-1.11.10.91.1-0.90.9-0.8
Patch foraging water rate 24 sec1.82.58.02.8-2.72.1-2.1-1.00.70.50.7-0.70.7-0.3
Patch foraging water rate 6 sec1.31.96.62.6-2.41.9-1.6-0.60.60.20.6-0.70.7-0.2
Seeking ratio, delayed vs. immediate footshock0.40.40.8-0.1-0.20.4-0.1-0.70.60.90.7-0.80.8-0.9
Distance traveled before self-admin0.30.30.5-0.70.7-0.70.40.4-0.7-0.3-0.60.5-0.50.6
Distance traveled after self-admin0.20.20.5-0.40.5-0.60.20.4-0.7-0.2-0.60.4-0.40.6
Extensor digitorum longus weight5.521.839.5-6.36.0-5.55.84.3-4.3-4.0-3.23.5-3.53.7
Bone: elastic displacement0.30.31.11.0-1.00.5-0.30.4-0.4-0.6-0.20.1-0.10.7
Bone: elastic work1.51.92.8-1.11.1-1.21.61.6-1.6-1.7-1.01.1-1.11.6
Bone: endosteal estimation1.94.25.71.2-1.41.9-1.9-2.32.12.32.0-2.42.4-2.1
Bone: endosteal perimeter2.44.97.41.6-1.52.0-2.3-2.52.42.71.9-2.42.4-2.4
Epididymis fat weight2.76.38.92.6-2.62.8-3.0-2.62.42.32.2-2.32.3-2.2
Delta time in closed arm before/after self-admin0.10.10.7-0.40.2-0.10.90.4-0.2-0.40.0-0.10.10.2
Delta time in open arm before/after self-admin0.20.20.50.00.1-0.4-0.30.3-0.3-0.3-0.60.7-0.70.4
Diff in mean of infusions in LGA sessions0.80.91.1-0.60.9-1.00.71.0-1.0-1.0-1.01.0-1.01.0
Delay discount exponential model param0.70.71.5-0.10.3-0.70.30.8-1.1-1.0-0.81.0-1.01.2
Extinction: sum of active levers before priming2.62.66.5-2.62.4-2.12.01.3-1.1-1.0-1.01.1-1.10.9
Active lever presses in extinction session 64.14.05.8-1.41.7-2.11.72.0-2.4-2.0-2.02.2-2.22.3
Bone: final force1.72.85.5-2.32.3-2.12.01.5-1.5-1.2-1.41.1-1.11.2
Bone: final moment1.52.44.8-2.12.2-2.01.91.4-1.3-1.1-1.31.0-1.01.1
Food consumed during 24 hour testing period0.40.51.00.20.2-0.50.10.6-0.7-0.6-0.91.0-1.00.8
Glucose3.45.26.61.6-1.92.3-2.1-2.52.52.62.3-2.42.4-2.5
Heart weight3.44.86.12.2-2.22.5-2.3-2.12.12.02.0-2.32.3-2.0
Delay discount hyperbolic model param0.50.61.3-0.10.3-0.60.20.8-1.0-0.9-0.80.8-0.81.1
Intermittent access intake day 1-15 change0.30.30.91.0-0.60.2-0.60.2-0.7-0.4-0.40.4-0.40.8
Intermittent access intake escalation0.20.20.80.9-0.60.3-0.6-0.1-0.4-0.1-0.10.0-0.00.4
Intermittent access intake escalation 20.40.40.90.6-0.3-0.1-0.30.4-0.8-0.6-0.70.6-0.61.0
Intermitt. access day 1 inactive lever presses1.81.93.51.7-1.71.5-1.9-1.41.11.31.1-1.21.2-0.8
Intermitt. access day 15 inactive lever presses1.31.43.11.8-1.31.3-1.6-1.20.71.00.9-1.01.0-0.6
Intermitt. access escalation Index5.24.65.51.7-1.82.3-1.9-2.22.32.02.4-2.32.3-2.2
Intermittent access day 1 total infusions9.210.713.62.4-2.43.2-2.9-3.53.73.63.5-3.43.4-3.7
Intermittent access day 15 total infusions6.97.810.33.2-2.93.1-3.2-2.82.62.72.6-2.52.5-2.4
Intermittent access terminal intake (last 3 days)5.56.17.72.6-2.32.6-2.8-2.62.42.52.4-2.32.3-2.3
Intermittent access total infusions6.26.98.32.2-2.02.6-2.5-2.82.82.92.8-2.72.7-2.8
Intermittent access day 1 locomotion7.37.610.71.7-1.82.6-2.1-2.93.23.13.2-2.92.9-3.3
Intermittent access day 15 total locomotion4.54.86.22.4-2.12.4-2.5-2.32.12.22.1-2.02.0-2.0
Intermittent access total locomotion8.810.012.32.6-2.53.2-3.1-3.53.33.53.3-3.23.2-3.3
Intermittent access standard deviation0.40.51.71.3-1.00.8-1.0-0.50.30.40.4-0.40.4-0.1
Left kidney weight0.30.92.31.3-1.51.0-1.4-0.90.10.41.0-0.80.80.1
Right kidney weight0.20.41.30.7-0.6-0.1-0.80.2-0.9-0.6-0.30.6-0.61.1
Cocaine induced anxiety0.10.10.20.0-0.2-0.2-0.00.2-0.3-0.3-0.10.4-0.40.4
Post-drug Anxiety2.22.43.1-1.11.1-1.61.11.6-1.7-1.6-1.71.8-1.81.7
Baseline Anxiety2.93.13.7-1.71.9-1.91.81.8-1.8-1.7-1.91.7-1.71.6
Tail length1.44.46.6-1.21.3-1.91.92.4-2.4-2.6-2.22.0-2.02.5
Length with tail2.810.212.0-2.93.1-3.43.43.5-3.4-3.2-3.22.9-2.93.2
Length without tail2.65.78.1-2.52.9-2.72.72.4-2.1-2.0-2.42.3-2.31.9
Times rat made contact with spout0.20.20.6-0.80.7-0.40.80.2-0.00.0-0.1-0.10.1-0.2
Lifetime Intake6.06.88.62.0-1.82.5-2.3-2.82.92.82.8-2.72.7-2.9
Liver weight, left0.00.00.20.2-0.40.3-0.2-0.20.1-0.10.3-0.10.10.0
Liver weight, right0.00.10.10.2-0.30.30.0-0.00.3-0.10.2-0.30.3-0.2
Locomotor activity0.50.83.11.8-1.61.3-1.1-0.40.50.00.2-0.30.3-0.2
Locomotor testing distance0.81.34.62.1-1.91.7-1.2-0.60.80.20.4-0.60.6-0.5
Locomotor testing rearing1.62.54.32.1-1.82.0-1.5-1.21.81.20.8-1.41.4-1.6
Locomotion in novel chamber3.13.97.62.8-2.62.3-2.6-1.91.51.61.6-1.41.4-1.2
Locomotion in novel chamber post-restriction2.02.44.12.0-1.91.9-1.9-1.51.21.21.4-1.21.2-1.1
Fecal boli incidents, locomotor time 10.10.20.4-0.00.3-0.4-0.20.1-0.4-0.3-0.50.6-0.60.4
Change in fecal boli incidents, locomotor task0.30.30.6-0.2-0.20.30.3-0.30.80.60.6-0.70.7-0.7
Time >=10cm from walls, locomotor time 12.32.34.00.8-1.01.2-1.4-1.81.72.01.5-1.61.6-1.8
Bouts of movement, locomotor time 11.21.31.8-1.11.0-1.41.11.1-1.3-0.9-1.31.0-1.01.2
Total resting periods, locomotor time 10.70.81.3-0.90.9-1.10.80.8-1.0-0.6-1.00.8-0.80.8
Rest time, locomotor task time 10.60.62.31.5-1.11.0-1.3-0.60.10.30.3-0.10.10.1
Distance moved, locomotor task time 10.30.30.5-0.60.30.00.4-0.40.60.60.7-0.60.6-0.7
Vertical activity count, locomotor time 10.80.81.61.1-1.31.1-0.9-0.80.90.60.8-0.70.7-0.7
Time >=10cm from walls, locomotor time 20.00.00.1-0.0-0.2-0.0-0.3-0.20.10.30.1-0.10.1-0.1
Bouts of movement, locomotor time 20.30.30.7-0.80.7-0.80.80.6-0.4-0.4-0.50.4-0.40.3
Total resting periods, locomotor time 20.10.10.4-0.60.5-0.50.50.2-0.2-0.0-0.20.1-0.10.1
Rest time, locomotor task time 21.92.23.31.8-1.81.8-1.8-1.51.11.31.5-1.21.2-1.0
Distance moved, locomotor task time 21.11.31.9-1.21.2-1.31.41.1-1.1-1.0-1.11.0-1.01.1
Vertical activity count, locomotor time 20.80.81.60.1-0.2-0.50.71.1-0.9-1.3-1.21.0-1.01.1
Light reinforcement 10.10.10.40.7-0.50.5-0.5-0.20.40.20.1-0.20.2-0.4
Light reinforcement 20.40.62.01.4-1.10.7-1.4-0.70.00.30.4-0.00.00.2
Bone: marrow area2.04.46.01.3-1.51.9-1.9-2.32.22.42.1-2.42.4-2.2
Bone: maximum diameter0.20.30.5-0.20.5-0.70.10.4-0.7-0.4-0.70.6-0.60.7
Bone: maximum force1.32.26.9-2.62.6-2.01.90.9-0.9-0.4-0.70.5-0.50.6
Bone: maximum moment1.11.96.0-2.42.4-1.91.70.8-0.8-0.3-0.60.4-0.40.5
Mean time between licks in bursts0.40.51.1-0.80.8-0.71.00.9-0.4-0.7-0.80.7-0.70.4
Mean num. licks in bursts0.40.40.80.4-0.50.7-0.4-0.50.70.60.5-0.90.9-0.7
Cd content in liver0.60.72.51.6-1.20.9-1.3-0.50.40.3-0.0-0.20.2-0.1
Co content in liver0.40.52.01.4-1.41.0-0.7-0.10.3-0.20.0-0.10.1-0.0
Cu content in liver0.20.20.7-0.80.7-0.50.60.1-0.2-0.10.10.3-0.30.1
Fe content in liver0.20.30.5-0.30.4-0.50.40.5-0.6-0.6-0.50.7-0.70.6
K content in liver0.70.72.7-1.71.5-0.91.10.2-0.20.10.2-0.40.4-0.1
Mg content in liver1.41.42.6-0.60.40.4-0.1-1.21.41.61.4-1.51.5-1.6
Mn content in liver1.82.13.8-1.81.9-1.91.51.3-1.3-1.0-1.41.1-1.11.2
Na content in liver1.81.92.6-1.01.1-1.41.01.3-1.6-1.5-1.21.6-1.61.5
Rb content in liver2.83.55.01.2-1.31.9-1.5-1.92.22.11.9-2.02.0-2.2
Se content in liver0.10.20.60.10.20.0-0.5-0.40.50.80.0-0.40.4-0.6
Sr content in liver4.13.84.6-1.51.7-2.11.72.1-2.1-2.0-2.12.0-2.02.0
Zn content in liver0.70.81.9-1.41.2-1.11.10.7-0.7-0.6-0.40.6-0.60.6
Bone: minimum diameter2.34.46.80.8-1.11.7-1.7-2.32.22.52.4-2.62.6-2.3
Time in familiar zone, hab. session 10.40.40.70.4-0.40.6-0.6-0.80.70.70.9-0.60.6-0.7
Time in novel zone, hab. session 10.10.10.30.5-0.50.3-0.00.3-0.0-0.2-0.40.1-0.10.1
Total zone transitions, hab. session 10.40.61.6-1.31.2-0.91.10.5-0.6-0.5-0.20.5-0.50.5
Total locomotion distance, hab. session 10.40.61.40.4-0.70.8-0.7-1.00.60.71.2-0.90.9-0.6
Locomotion velocity, hab. session 10.10.20.6-0.1-0.20.3-0.2-0.50.20.30.8-0.60.6-0.3
Time in familiar zone, hab. session 20.10.20.40.0-0.0-0.00.50.5-0.2-0.6-0.30.5-0.50.3
Time in novel zone, hab. session 20.20.20.5-0.20.20.1-0.2-0.50.50.70.4-0.70.7-0.6
Total zone transitions, hab. session 20.81.12.4-1.61.3-0.30.8-0.61.11.30.6-0.80.8-1.4
Total locomotion distance, hab. session 21.01.32.4-0.2-0.20.8-0.4-1.31.41.51.5-1.31.3-1.5
Locomotion velocity, hab. session 21.11.52.50.0-0.40.9-0.6-1.41.41.61.6-1.31.3-1.6
Novel to familiar place preference ratio0.40.41.1-0.91.0-1.00.50.3-0.4-0.1-0.60.4-0.40.3
Novelty place preference0.10.10.4-0.50.6-0.60.1-0.0-0.10.2-0.30.1-0.10.0
Time in novel zone, NPP test0.10.10.3-0.40.5-0.40.0-0.10.00.3-0.2-0.00.0-0.1
Total zone transitions, NPP test0.81.23.9-2.01.8-1.41.50.6-0.5-0.4-0.50.3-0.30.3
Total locomotion distance, NPP test0.20.20.6-0.50.10.10.1-0.50.30.40.8-0.70.7-0.4
Locomotion velocity, NPP test0.10.10.5-0.50.2-0.00.1-0.40.10.30.7-0.50.5-0.2
Intraocular pressure0.40.52.01.4-1.20.5-1.3-0.0-0.2-0.2-0.40.2-0.20.4
Delta distance traveled before/after self-admin0.00.00.00.2-0.00.0-0.00.1-0.1-0.1-0.10.0-0.00.1
Delta ambulatory time before/after self-admin0.00.00.10.00.0-0.10.20.3-0.2-0.2-0.20.1-0.10.2
Parametrial fat weight3.46.67.91.9-2.52.7-2.7-2.82.62.52.8-2.72.7-2.4
Pavlov. Cond. lever latency0.10.10.50.7-0.50.4-0.3-0.00.20.1-0.2-0.00.0-0.1
Pavlov. Cond. magazine entry latency0.30.30.8-0.40.30.1-0.2-0.70.60.90.8-0.50.5-0.7
Pavlov. Cond. change in total contacts0.10.10.2-0.20.1-0.1-0.4-0.5-0.00.30.40.1-0.1-0.0
Pavlov. Cond. index score0.10.10.2-0.30.2-0.30.00.0-0.2-0.10.00.4-0.40.3
Pavlov. Cond. latency score0.00.00.1-0.20.1-0.1-0.1-0.20.00.10.30.1-0.1-0.0
Pavlov. Cond. lever contacts0.00.00.1-0.2-0.0-0.0-0.0-0.2-0.0-0.00.40.0-0.0-0.0
Pavlov. Cond. magazine entry number0.30.30.70.4-0.50.6-0.2-0.40.60.40.4-0.80.8-0.7
Pavlov. Cond. intertrial magazine entries0.10.10.50.7-0.40.2-0.50.0-0.1-0.2-0.1-0.10.10.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.60.5-0.50.20.1-0.4-0.2-0.00.5-0.50.3
Pavlov. Cond. response bias0.10.10.4-0.20.3-0.40.10.2-0.4-0.3-0.10.6-0.60.5
Pavlov. Cond. lever latency0.30.50.90.8-0.90.9-0.6-0.50.60.40.6-0.70.7-0.5
Pavlov. Cond. magazine entry latency2.02.35.8-2.32.4-1.91.91.1-1.0-0.7-0.91.1-1.10.6
Pavlov. Cond. change in total contacts0.91.33.5-1.61.9-1.61.00.7-0.8-0.3-0.81.0-1.00.6
Pavlov. Cond. index score1.41.84.4-1.92.1-1.81.51.0-1.1-0.7-0.91.1-1.10.8
Pavlov. Cond. latency score1.21.53.5-1.71.9-1.61.30.9-1.1-0.6-0.71.0-1.00.8
Pavlov. Cond. lever contacts0.60.91.4-0.61.0-1.10.70.9-0.9-0.8-1.11.2-1.20.8
Pavlov. Cond. magazine entry number3.74.510.33.0-3.22.7-2.6-1.71.51.11.6-1.71.7-1.1
Pavlov. Cond. intertrial magazine entries0.81.02.01.4-1.41.2-1.3-0.90.80.70.7-0.80.8-0.7
Pavlov. Cond. lever-magazine prob. diff.1.72.25.1-2.12.3-2.01.71.1-1.2-0.8-1.01.2-1.20.9
Pavlov. Cond. response bias1.31.73.3-1.51.8-1.71.31.1-1.0-0.8-1.21.4-1.40.8
Time in closed arm before self-admin0.00.00.20.00.0-0.0-0.4-0.20.20.3-0.10.1-0.1-0.2
Time in closed arm after self-admin0.00.00.1-0.1-0.10.10.1-0.20.00.10.4-0.40.4-0.0
Time in open arm before self-admin0.50.51.00.5-0.60.9-0.1-0.50.60.41.0-1.01.0-0.6
Time in open arm after self-admin0.10.10.30.5-0.50.3-0.30.1-0.0-0.2-0.20.3-0.30.1
Bone: periosteal estimation0.10.10.30.0-0.00.1-0.4-0.50.20.50.6-0.50.5-0.2
Bone: periosteal perimeter0.00.10.2-0.20.4-0.2-0.1-0.30.20.50.1-0.20.2-0.3
Bone: post-yield work2.43.27.0-1.00.60.4-0.7-2.21.82.72.1-2.12.1-2.2
Progressive ratio test 1 active lever presses2.52.63.41.8-1.71.8-1.8-1.61.51.51.5-1.41.4-1.5
Progressive ratio test 1 breakpoint1.92.03.11.8-1.61.7-1.7-1.41.31.31.3-1.11.1-1.3
Progressive ratio test 1 inactive lever presses1.31.51.81.2-1.11.3-1.1-1.21.21.31.1-1.31.3-1.2
Progressive ratio test 2 active lever presses3.53.85.22.3-1.92.1-2.2-2.01.91.91.9-1.71.7-1.8
Progressive ratio test 2 breakpoint3.54.07.12.7-2.22.3-2.5-1.91.81.81.8-1.61.6-1.6
Progressive ratio test 2 inactive lever presses8.49.712.13.4-3.13.4-3.5-3.23.13.12.6-2.92.9-2.9
Incentive Sensitization - Responses0.40.50.70.6-0.30.6-0.7-0.70.80.80.7-0.70.7-0.7
Incentive Sensitization - Breakpoint0.60.60.70.8-0.50.7-0.8-0.80.80.80.8-0.70.7-0.7
Sum of active levers in priming session hrs 5-64.74.57.0-0.91.4-2.11.32.1-2.6-2.2-2.42.5-2.52.6
Progressive ratio0.80.93.2-1.81.5-0.71.0-0.20.50.70.5-0.60.6-0.9
Food seeking constrained by brief footshock0.30.40.8-0.60.6-0.50.90.7-0.8-0.6-0.50.4-0.40.6
Seeking ratio, punishment vs. effort0.50.62.41.5-1.40.9-0.70.1-0.3-0.5-0.10.2-0.20.6
Retroperitoneal fat weight4.815.921.44.4-4.44.5-4.6-4.03.63.63.8-3.73.7-3.3
Reaction time number correct0.71.11.6-0.50.7-0.90.81.1-1.2-1.1-1.01.2-1.21.3
Reaction time mean minus median2.22.94.6-2.12.0-2.11.71.5-1.5-1.2-1.61.6-1.61.3
Reaction time mean minus median AUC2.02.63.3-1.61.5-1.81.61.5-1.6-1.5-1.51.7-1.71.5
Reaction time num false alarms0.10.10.40.2-0.40.30.20.2-0.4-0.60.20.1-0.10.4
Reaction time num false alarms AUC0.30.51.2-0.60.3-0.40.90.7-0.8-1.1-0.20.6-0.60.8
Reaction time trials correct on left0.71.11.6-0.50.7-0.90.81.1-1.2-1.1-1.01.2-1.21.3
Reaction time trials on left1.01.42.0-0.60.8-1.10.91.3-1.4-1.3-1.11.3-1.31.4
Reaction time mean0.00.10.3-0.1-0.0-0.3-0.10.1-0.1-0.2-0.30.5-0.50.1
Reaction time mean AUC0.00.00.1-0.1-0.1-0.2-0.2-0.1-0.0-0.0-0.10.4-0.4-0.0
Median of all reaction times0.10.10.20.3-0.50.3-0.5-0.40.30.30.20.0-0.0-0.3
Reaction time omissions1.52.02.6-1.61.3-1.61.51.3-1.5-1.4-0.81.6-1.61.3
Reaction time false alarm rate0.00.10.20.1-0.30.30.1-0.0-0.1-0.30.5-0.20.20.1
Reaction time premature initiation rate2.12.94.5-1.81.6-1.72.11.9-1.4-1.7-1.81.6-1.61.3
Reaction time premature initiations4.36.17.7-2.32.3-2.52.82.7-2.3-2.5-2.62.4-2.42.2
Std. dev. reaction times0.70.91.5-1.00.9-1.20.80.8-0.9-0.8-1.11.1-1.10.7
Reaction time trials completed1.01.42.0-0.60.8-1.10.91.3-1.4-1.3-1.11.3-1.31.4
Reaction time trials AUC0.60.91.3-0.40.6-0.80.71.0-1.1-1.1-0.91.1-1.11.1
Run reversals in cocaine runway, females0.70.71.5-1.10.6-0.00.7-0.50.90.61.2-0.80.8-1.1
Run reversals in cocaine runway, males0.90.91.90.6-0.4-0.20.11.0-1.1-1.4-0.81.2-1.21.3
Latency to leave start box in cocaine runway0.40.41.0-0.1-0.00.4-0.3-0.80.70.91.0-0.70.7-0.8
Latency to leave start box in cocaine runway, F0.20.20.5-0.20.10.2-0.0-0.60.50.60.7-0.40.4-0.6
Latency to leave start box in cocaine runway, M0.00.00.0-0.10.1-0.1-0.1-0.1-0.00.10.20.1-0.1-0.0
Std. dev. time between licks in bursts0.10.10.40.1-0.30.10.30.5-0.2-0.6-0.20.3-0.30.3
Total sessions with >9 infusions2.73.03.91.2-1.41.7-1.4-1.81.81.82.0-1.91.9-1.9
Short access day 1 total inactive lever presses3.84.35.42.1-2.02.3-2.3-2.12.22.01.9-1.91.9-2.0
Short access day 10 total inactive lever presses2.42.64.22.0-2.01.9-1.9-1.51.31.21.4-1.51.5-1.1
Short access day 1 total infusions6.06.48.41.6-1.72.4-2.1-2.72.82.72.9-2.82.8-2.9
Short access day 10 total infusions5.35.89.70.8-0.81.9-1.4-2.62.92.93.0-2.82.8-3.1
Short access total infusions3.54.06.50.9-1.01.8-1.3-2.12.42.22.4-2.22.2-2.5
Short access day 1 locomotion4.44.76.91.4-1.32.0-1.6-2.32.52.42.5-2.42.4-2.6
Short access day 10 total locomotion3.43.85.71.1-1.11.8-1.3-2.12.12.32.4-2.32.3-2.2
Short access total locomotion3.43.55.30.9-1.01.7-1.2-2.02.22.12.3-2.12.1-2.2
One hour access (0.3 mA shock)8.09.314.03.7-3.43.4-3.4-2.92.82.82.7-2.82.8-2.6
Compulsive drug intake2.82.84.6-1.81.6-1.72.21.9-1.5-1.7-1.61.5-1.51.4
One hour access (shock baseline)7.08.112.93.6-3.23.1-3.6-2.92.52.72.5-2.42.4-2.3
Social response proportion0.30.40.9-0.91.0-0.90.60.5-0.2-0.0-0.90.3-0.30.1
Social responses0.30.31.0-0.40.6-0.60.60.7-0.3-0.5-1.00.4-0.40.3
Social time0.40.51.1-0.50.7-0.70.80.8-0.5-0.7-1.00.8-0.80.5
Soleus weight2.78.014.23.6-3.83.4-3.4-2.72.02.02.6-2.62.6-1.5
Bone: stiffness0.91.44.7-2.22.2-1.61.40.5-0.5-0.0-0.50.3-0.30.1
Tibialis anterior weight10.736.746.5-6.56.7-6.86.76.0-6.1-5.8-5.25.5-5.55.6
Time to tail flick, vehicle, before self-admin0.10.10.6-0.80.6-0.40.60.0-0.00.10.1-0.10.1-0.1
Time to tail flick, vehicle, after self-admin0.50.52.3-1.51.1-0.71.20.3-0.0-0.10.1-0.20.2-0.2
Time to tail flick, test, before self-admin2.32.34.00.4-0.71.3-0.6-1.51.71.61.8-2.02.0-1.8
Time to tail flick, test, after self-admin0.00.00.10.10.0-0.20.00.2-0.0-0.1-0.40.2-0.20.1
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.80.6-0.40.70.20.0-0.00.0-0.10.1-0.1
Delta time to tail flick, test, before/after SA4.03.65.6-0.70.9-1.71.12.0-2.0-2.1-2.42.3-2.32.1
Tibia length1.64.56.2-1.51.8-2.31.52.0-2.5-1.9-2.12.4-2.42.5
Ambulatory time before self-admin0.30.30.5-0.50.6-0.70.10.3-0.7-0.2-0.60.6-0.60.6
Ambulatory time after self-admin0.20.30.70.3-0.20.3-0.7-0.70.20.90.4-0.50.5-0.3
Bone: tissue strength0.00.00.1-0.10.2-0.1-0.1-0.20.10.4-0.1-0.20.2-0.2
Total heroin consumption4.55.28.2-2.82.9-2.72.52.1-2.1-1.9-1.92.1-2.11.8
Bone: trabecular number0.40.61.3-0.91.0-0.30.2-0.50.81.10.3-0.60.6-1.1
Bone: trabecular spacing0.10.10.40.5-0.60.5-0.2-0.1-0.0-0.20.3-0.10.10.2
Bone: trabecular thickness1.21.52.80.6-0.61.0-1.0-1.41.61.61.2-1.11.1-1.7
Bone: trabecular tissue density1.82.66.12.5-2.41.9-2.3-1.40.80.91.1-1.11.1-0.5
Water consumed over 24 hours0.50.61.0-0.81.0-0.91.00.8-0.4-0.4-0.90.7-0.70.3
Number of responses in last shaping day0.60.61.51.2-1.01.1-1.0-0.60.80.40.6-0.40.4-0.7