Hub : Genes

RGD1359108

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression RGD1359108 0.31 0.16 2.1e-05 0.12 0.07 0.12 0.12 4.9e-04 7.8e-03 3.9e-04 4.0e-04
2 BLA mRNA stability RGD1359108 0.08 0.06 4.0e-03 0.04 0.04 0.02 0.04 5.4e-03 4.8e-03 2.5e-02 5.7e-03
3 NAcc alternative TSS XM_039109829.1 0.05 0.04 9.5e-04 0.04 0.02 0.03 0.04 1.9e-05 1.6e-03 7.7e-05 5.0e-05
4 NAcc alternative TSS NM_001007702.2 0.05 0.03 8.7e-04 0.04 0.02 0.02 0.03 5.1e-05 2.4e-03 4.7e-03 2.7e-04
5 NAcc alternative TSS XM_039109829.1 0.05 0.03 5.3e-04 0.04 0.02 0.03 0.03 3.3e-05 2.0e-03 1.7e-04 2.0e-04
6 Adipose isoform ratio XM_039109830.1 0.09 0.05 1.7e-06 0.04 0.04 0.03 0.04 2.8e-05 3.9e-05 1.3e-04 5.2e-05
7 PL mRNA stability RGD1359108 0.09 0.07 4.7e-05 0.04 0.03 0.03 0.04 3.3e-05 3.2e-04 1.2e-04 8.0e-05
8 Adipose gene expression RGD1359108 0.19 0.11 8.0e-12 0.09 0.08 0.07 0.09 8.8e-10 5.2e-09 1.8e-08 1.1e-09
9 Liver alternative polyA NM_001007702.2 0.03 0.02 4.9e-03 0.01 0 -0 0 1.2e-02 9.2e-02 3.9e-01 1.1e-01
10 Liver alternative polyA XM_039109830.1 0.03 0.03 1.5e-03 0.02 0.01 0.01 0.01 3.4e-03 1.5e-02 3.1e-02 2.7e-02
11 Liver isoform ratio NM_001007702.2 0.03 0.02 6.8e-03 0.02 0 0.01 0.01 3.8e-03 1.0e-01 5.4e-02 3.6e-02
12 NAcc alternative polyA NM_001007702.2 0.03 0.03 6.7e-03 0.01 0 0 0 1.8e-02 9.0e-02 1.0e-01 7.9e-02
13 Brain isoform ratio XM_039109830.1 0.07 0.05 8.6e-05 0.05 0.03 0.02 0.04 1.8e-05 4.8e-04 3.7e-03 6.0e-05
14 PL alternative TSS XM_039109829.1 0.03 0.02 4.4e-03 0.01 0.01 0 0.01 2.8e-02 4.0e-02 1.0e-01 3.4e-02
15 Brain alternative polyA XM_039109830.1 0.14 0.08 8.7e-09 0.09 0.08 0.07 0.08 8.9e-09 7.8e-08 2.4e-07 3.0e-08
16 Brain mRNA stability RGD1359108 0.1 0.06 1.4e-06 0.08 0.07 0.07 0.07 1.3e-07 8.6e-07 1.7e-07 2.5e-07
17 NAcc mRNA stability RGD1359108 0.07 0.04 1.9e-06 0.02 0.04 0.03 0.03 7.9e-04 1.2e-05 1.1e-04 1.5e-04
18 Adipose alternative polyA XM_039109830.1 0.09 0.06 4.7e-07 0.04 0.04 0.03 0.04 2.1e-05 4.1e-05 2.0e-04 5.5e-05
19 PL gene expression RGD1359108 0.28 0.14 1.0e-05 0.04 0.05 0.05 0.04 6.6e-05 2.9e-06 7.8e-06 8.7e-05
20 PL isoform ratio XM_039109830.1 0.08 0.05 1.8e-06 0.05 0.06 0.06 0.05 5.2e-06 8.3e-07 7.5e-07 4.5e-06
21 NAcc isoform ratio XM_039109830.1 0.05 0.04 1.3e-03 0.02 0.02 0.01 0.02 2.3e-03 4.6e-03 1.7e-02 2.2e-03
22 PL alternative polyA NM_001007702.2 0.04 0.03 2.3e-03 0.02 0.01 0.02 0.01 4.5e-03 1.5e-02 2.8e-03 1.0e-02
23 NAcc isoform ratio NM_001007702.2 0.05 0.05 4.8e-03 0.01 0 0 0 2.4e-02 1.4e-01 1.1e-01 7.4e-02
24 PL alternative TSS NM_001007702.2 0.03 0.02 6.2e-03 0.01 0.01 0 0.01 3.8e-02 4.7e-02 1.2e-01 5.4e-02
25 OFC gene expression RGD1359108 0.2 0.13 2.5e-03 -0.01 0.09 0.03 0.04 4.7e-01 3.8e-03 5.8e-02 3.7e-02
26 BLA gene expression RGD1359108 0.12 0.09 2.2e-04 0.04 0.04 0.05 0.04 2.0e-03 4.3e-03 8.8e-04 3.5e-03
27 IL gene expression RGD1359108 0.26 0.16 2.3e-03 0.02 0 0.01 0.02 1.2e-01 2.6e-01 2.2e-01 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.61.02.71.41.31.1-1.11.11.1-1.11.1-0.80.8-0.8-1.11.01.10.9-0.91.60.80.91.3-0.1-0.90.40.41.6-0.3-0.8
Area under the delay curve0.10.10.80.20.30.4-0.40.50.5-0.50.3-0.00.0-0.0-0.50.50.50.4-0.30.30.30.90.4-0.3-0.2-0.1-0.10.1-0.2-0.1
BMI with tail2.68.513.13.12.52.9-2.93.13.1-3.12.8-3.53.5-3.5-3.13.03.12.7-2.60.92.62.12.8-3.3-3.5-3.6-3.6-0.42.81.8
BMI without tail2.04.27.12.72.42.0-2.02.02.1-2.11.9-2.62.6-2.6-2.22.02.21.9-2.02.22.11.01.7-2.1-1.6-1.8-1.81.81.5-1.2
Body weight6.225.834.55.85.55.6-5.65.75.8-5.95.5-5.35.3-5.3-5.85.75.85.4-5.24.25.24.85.3-4.8-5.1-4.3-4.32.63.3-0.2
Weight adjusted by age1.82.13.31.41.71.1-1.11.11.6-1.60.9-1.81.8-1.8-1.61.71.61.8-1.81.61.70.61.0-1.4-0.7-1.1-1.11.41.5-1.1
Bone surface1.42.57.01.92.11.5-1.51.51.6-1.61.6-1.71.7-1.7-1.51.51.51.4-1.32.61.60.91.6-0.6-0.90.20.22.60.1-1.8
Bone volume0.81.45.31.61.61.1-1.11.11.1-1.11.1-1.11.1-1.1-1.11.01.10.9-0.82.20.80.71.20.1-0.70.80.82.3-0.6-1.5
Breakpoint value in progressive ratio session0.30.41.7-0.30.40.4-0.40.3-0.30.20.30.0-0.00.0-0.1-0.3-0.0-0.30.51.0-0.5-0.1-0.20.70.31.01.01.2-1.3-1.2
Number of licking bursts0.10.10.4-0.6-0.1-0.20.2-0.2-0.20.2-0.40.2-0.20.20.3-0.2-0.2-0.2-0.20.10.2-0.10.20.0-0.10.30.30.20.40.3
Context. condit. distance diff. score0.50.71.4-0.9-1.1-0.80.8-0.8-0.90.9-0.81.0-1.01.00.8-1.0-0.8-0.80.9-1.2-0.8-0.5-0.60.40.40.10.1-1.1-0.30.7
Locomotion velocity, session 10.20.20.7-0.6-0.6-0.50.5-0.5-0.50.5-0.50.3-0.30.30.5-0.5-0.5-0.40.2-0.8-0.2-0.4-0.50.10.4-0.0-0.0-0.80.60.4
Locomotion distance, session 12.43.06.4-2.5-2.1-1.81.8-1.8-1.81.8-1.82.3-2.32.31.8-1.8-1.8-1.71.7-1.8-1.5-0.8-1.71.51.71.31.3-1.4-1.20.1
Locomotion velocity, session 20.40.51.3-0.50.20.6-0.60.60.6-0.60.60.1-0.10.1-0.60.50.60.5-0.8-0.30.81.10.7-0.9-0.8-0.9-0.9-0.60.91.0
Locomotion distance, session 23.85.311.2-3.3-2.9-2.32.3-2.3-2.22.2-2.32.8-2.82.82.3-2.3-2.3-2.42.3-3.1-2.3-1.2-2.21.81.81.11.1-2.8-1.51.5
Locomotion velocity, session 31.61.94.9-1.6-1.9-1.31.3-1.3-1.31.3-1.31.6-1.61.61.3-1.4-1.3-1.41.4-2.2-1.3-0.7-1.20.80.90.30.3-2.2-0.41.3
Locomotion distance, session 31.81.96.5-1.5-1.9-1.11.1-1.1-1.11.1-1.11.8-1.81.81.1-1.2-1.1-1.41.5-2.5-1.3-0.1-0.80.80.40.30.3-2.6-0.61.9
Stereotopy head waving bouts, day 30.50.61.80.61.10.7-0.70.70.8-0.80.7-0.80.8-0.8-0.70.80.70.9-0.71.30.90.50.7-0.6-0.3-0.2-0.21.3-0.0-1.0
Stereotopy head waving duration, day 31.31.62.31.21.41.2-1.21.21.4-1.31.2-1.41.4-1.4-1.31.41.31.5-1.41.21.40.71.1-1.5-1.0-1.4-1.40.91.1-0.2
Locomotion velocity, session 70.50.53.2-1.0-0.9-0.30.3-0.3-0.30.3-0.30.8-0.80.80.3-0.4-0.3-0.30.3-1.6-0.10.2-0.2-0.5-0.2-0.8-0.8-1.80.41.4
Locomotion distance, session 70.81.14.0-1.3-1.5-0.80.8-0.8-0.70.7-0.81.4-1.41.40.8-0.8-0.8-1.00.9-1.9-0.70.0-0.50.60.20.30.3-2.0-0.21.6
Stereotopy head waving bouts, day 71.01.13.80.70.41.0-1.01.01.0-1.01.0-0.80.8-0.8-1.00.91.00.9-0.8-0.50.71.00.6-1.5-1.1-1.9-1.9-1.11.31.3
Stereotopy head waving duration, day 72.12.65.81.61.31.7-1.71.71.7-1.71.7-1.61.6-1.6-1.71.61.71.6-1.40.41.31.41.4-2.1-1.9-2.4-2.4-0.31.71.2
Locomotion velocity, session 83.13.711.4-2.6-2.7-1.71.7-1.7-1.81.8-1.72.3-2.32.31.8-1.9-1.7-1.81.8-3.3-1.8-0.8-2.00.51.3-0.3-0.3-3.4-0.22.1
Locomotion distance, session 84.36.411.6-3.2-3.3-2.52.5-2.5-2.52.5-2.53.3-3.33.32.5-2.6-2.5-2.52.6-3.4-2.6-1.2-2.21.91.81.21.2-3.0-1.51.8
Degree of sensitization distance0.50.51.10.60.60.6-0.60.60.7-0.70.6-0.70.7-0.7-0.60.80.70.8-0.90.30.90.50.6-0.8-0.7-0.7-0.70.11.00.3
Degree of sensitization stereotypy1.11.24.80.60.10.8-0.80.80.8-0.80.8-0.70.7-0.7-0.80.70.80.6-0.5-1.10.40.80.3-1.6-1.2-2.2-2.2-1.81.51.8
Conditioned locomotion0.10.20.8-0.00.50.4-0.40.40.4-0.40.3-0.20.2-0.2-0.40.20.40.3-0.30.80.30.40.30.0-0.10.20.20.9-0.5-0.9
Cocaine response after cond. corrected0.70.81.10.91.01.0-1.01.00.9-0.90.9-1.01.0-1.0-0.90.91.01.0-0.90.91.00.70.8-0.8-0.6-0.6-0.60.70.6-0.5
Cocaine response after cond. not corrected0.50.60.90.70.80.9-0.90.90.9-0.90.8-0.60.6-0.6-0.80.90.90.9-1.00.80.91.00.8-0.7-0.5-0.4-0.40.60.3-0.5
Cocaine response before conditioning0.10.10.5-0.00.00.2-0.20.20.3-0.30.30.2-0.20.2-0.30.40.20.4-0.4-0.10.10.70.5-0.3-0.4-0.2-0.2-0.20.10.3
Saline control response1.62.14.41.71.81.6-1.61.61.5-1.51.6-1.41.4-1.4-1.51.51.61.7-1.42.11.31.31.2-0.7-0.6-0.1-0.12.0-0.1-1.8
Bone: connectivity density0.81.32.51.31.51.3-1.31.31.3-1.31.3-1.11.1-1.1-1.31.21.31.2-1.11.61.20.91.3-0.6-0.9-0.1-0.11.50.3-0.7
Bone: cortical apparent density0.10.20.7-0.5-0.3-0.60.6-0.6-0.60.6-0.60.0-0.00.00.6-0.6-0.6-0.40.3-0.0-0.2-0.8-0.30.20.10.30.30.20.20.2
Bone: cortical area3.65.48.02.82.72.5-2.52.52.5-2.52.5-2.72.7-2.7-2.52.52.52.6-2.62.52.51.82.1-1.9-1.9-1.5-1.52.01.7-1.1
Bone: cortical porosity0.60.63.50.80.80.3-0.30.30.3-0.30.30.1-0.10.1-0.30.30.30.3-0.31.60.30.40.70.60.21.31.31.9-1.3-1.8
Bone: cortical porosity0.91.02.51.31.31.0-1.01.01.0-1.01.0-0.70.7-0.7-1.01.01.00.9-1.01.60.91.01.1-0.4-0.40.10.11.5-0.3-1.5
Bone: cortical thickness1.32.23.51.81.61.5-1.51.51.5-1.51.5-1.51.5-1.5-1.51.61.51.8-1.91.51.71.31.6-1.2-1.5-1.0-1.01.21.4-0.3
Bone: cortical thickness0.70.83.81.00.40.7-0.70.70.7-0.70.6-1.01.0-1.0-0.70.70.71.0-1.0-0.10.90.40.4-1.0-0.9-1.2-1.2-0.62.00.7
Bone: cortical tissue density0.10.20.6-0.5-0.3-0.60.6-0.6-0.60.6-0.6-0.00.0-0.00.6-0.5-0.6-0.30.30.1-0.2-0.8-0.20.20.10.40.40.30.20.1
Condit. Reinf. active minus inactive responses2.12.43.8-1.4-2.0-1.61.6-1.6-1.71.7-1.61.8-1.81.81.7-1.6-1.7-1.71.5-2.0-1.6-1.1-1.61.31.20.90.9-1.7-0.51.1
Condit. Reinf. active-inactive response ratio0.60.60.9-0.7-0.9-0.90.9-0.9-0.90.9-0.90.8-0.80.80.9-0.9-0.9-0.80.7-0.8-0.8-0.7-0.90.60.80.60.6-0.7-0.10.4
Condit. Reinf. active responses1.41.73.6-1.1-1.7-1.41.4-1.4-1.41.4-1.41.4-1.41.41.4-1.3-1.4-1.51.3-1.9-1.3-1.0-1.30.90.90.40.4-1.8-0.30.9
Condit. Reinf. inactive responses0.80.92.2-0.8-1.3-1.01.0-1.0-1.01.0-1.00.8-0.80.81.1-1.0-1.0-1.11.0-1.5-1.0-0.9-1.10.70.70.20.2-1.4-0.30.4
Incentive salience index mean0.60.71.7-1.0-1.2-0.90.9-0.9-0.90.9-0.91.0-1.01.00.9-0.9-0.9-1.00.8-1.3-0.8-0.5-0.80.40.50.10.1-1.20.10.9
Condit. Reinf. lever presses0.30.41.5-0.6-0.10.3-0.30.30.2-0.20.3-0.10.1-0.1-0.20.20.20.1-0.4-0.50.50.60.3-1.0-0.7-1.2-1.2-0.71.20.9
Condit. Reinf. active minus inactive responses2.22.76.61.81.41.9-1.91.92.0-2.02.0-0.60.6-0.6-1.91.91.91.9-1.90.81.52.61.8-1.6-1.7-1.6-1.60.11.10.7
Condit. Reinf. active-inactive response ratio1.31.44.00.40.31.0-1.01.01.1-1.11.1-0.20.2-0.2-1.11.01.01.1-1.3-0.70.91.50.7-1.6-1.3-2.0-2.0-1.41.81.7
Condit. Reinf. active responses2.43.47.72.31.92.2-2.22.22.2-2.22.3-0.90.9-0.9-2.22.22.22.2-2.01.81.82.82.2-1.3-1.6-1.0-1.01.40.2-0.6
Condit. Reinf. inactive responses1.72.14.72.11.71.6-1.61.61.5-1.51.7-0.60.6-0.6-1.61.51.61.5-1.12.21.22.01.8-0.3-0.80.30.32.1-1.1-1.7
Condit. Reinf. lever presses2.43.35.12.01.71.9-1.91.92.0-2.01.9-1.31.3-1.3-1.92.11.92.3-2.21.32.12.02.0-2.0-1.8-1.9-1.90.71.90.2
Condit. Reinf. lever reinforcers received2.83.97.82.42.12.3-2.32.32.3-2.32.4-1.11.1-1.1-2.32.32.32.3-2.21.92.02.82.4-1.5-1.8-1.2-1.21.40.5-0.6
Conditioned reinforcement - actives0.30.31.10.30.20.2-0.20.20.4-0.40.1-0.50.5-0.5-0.20.50.20.5-0.6-0.30.3-0.00.3-0.8-0.6-1.1-1.1-0.60.90.9
Conditioned reinforcement - inactives0.70.72.50.30.60.9-0.90.91.2-1.10.80.1-0.10.1-0.81.30.71.3-1.20.31.01.60.7-1.1-0.6-0.9-0.9-0.10.90.4
Conditioned locomotion0.10.20.7-0.20.20.1-0.10.20.00.0-0.1-0.80.8-0.80.1-0.0-0.20.2-0.2-0.00.1-0.5-0.2-0.60.1-0.7-0.7-0.10.50.1
Patch foraging indifference point 0 sec0.20.41.11.00.70.9-0.90.70.5-0.51.0-0.50.5-0.5-0.40.40.50.3-0.30.90.10.50.4-0.0-0.20.00.00.8-0.7-0.9
Patch foraging indifference point AUC1.11.32.61.31.21.2-1.21.11.0-1.01.1-1.61.6-1.6-1.01.11.01.2-1.31.01.20.41.1-1.1-1.2-1.1-1.10.71.1-0.1
Delay disc. indifference point, 0s delay0.10.10.50.0-0.5-0.20.2-0.2-0.30.2-0.30.4-0.40.40.3-0.2-0.3-0.10.1-0.7-0.30.0-0.2-0.10.1-0.2-0.2-0.70.20.4
Delay disc. indifference point, 16s delay0.90.93.40.50.91.2-1.21.41.1-1.21.2-0.40.4-0.4-1.21.11.21.0-0.90.81.01.81.0-0.8-0.7-0.5-0.50.50.1-0.3
Delay disc. indifference point, 2s delay0.10.10.30.30.40.0-0.00.10.3-0.30.0-0.40.4-0.4-0.10.30.20.3-0.20.50.20.00.1-0.20.2-0.0-0.00.5-0.1-0.6
Delay disc. indifference point, 24s delay0.50.51.50.10.60.8-0.80.80.8-0.90.8-0.20.2-0.2-1.00.71.00.6-0.50.50.71.21.0-0.3-1.0-0.1-0.10.30.20.8
Delay disc. indifference point, 4s delay0.10.10.5-0.3-0.4-0.20.2-0.1-0.30.3-0.30.7-0.70.70.2-0.3-0.2-0.30.3-0.4-0.40.4-0.10.30.30.30.3-0.4-0.60.1
Delay disc. indifference point, 8s delay0.10.10.70.10.10.2-0.20.10.1-0.20.10.3-0.30.3-0.20.10.30.00.00.2-0.20.60.20.20.10.40.40.2-0.8-0.3
Indifference point function ln k0.40.51.4-1.2-0.9-0.90.9-0.7-0.70.7-0.81.0-1.01.00.7-0.7-0.7-0.60.5-0.9-0.5-0.1-0.40.20.30.20.2-0.8-0.01.0
Indifference point function log k0.40.51.4-1.2-0.9-0.90.9-0.7-0.70.7-0.81.0-1.01.00.7-0.7-0.7-0.60.5-0.9-0.5-0.1-0.40.20.30.20.2-0.8-0.01.0
Patch foraging total patch changes 0 sec0.20.41.11.10.70.9-0.90.70.6-0.61.0-0.40.4-0.4-0.50.50.50.5-0.50.60.20.70.5-0.2-0.3-0.3-0.30.5-0.5-0.6
Patch foraging total patch changes 12 sec1.72.23.51.81.21.8-1.81.61.5-1.51.8-1.41.4-1.4-1.51.51.51.4-1.40.41.21.31.6-1.6-1.9-1.9-1.9-0.21.20.8
Patch foraging total patch changes 18 sec0.40.52.01.40.80.9-0.90.60.7-0.70.9-0.90.9-0.9-0.40.70.40.8-0.90.70.60.30.6-0.2-0.5-0.1-0.10.50.4-0.4
Patch foraging total patch changes 24 sec1.01.33.51.41.41.3-1.31.11.1-1.11.3-1.31.3-1.3-1.01.11.01.1-1.21.41.20.60.6-0.8-0.1-0.4-0.41.30.4-1.9
Patch foraging total patch changes 6 sec0.60.91.61.31.21.2-1.21.11.0-1.01.2-0.80.8-0.8-1.01.01.00.9-0.81.20.80.91.1-0.4-0.7-0.2-0.21.1-0.2-0.7
Patch foraging time to switch 0 sec1.52.33.5-1.8-1.5-1.71.7-1.6-1.51.4-1.71.9-1.91.91.4-1.6-1.4-1.51.6-1.1-1.3-1.0-1.31.71.41.81.8-0.6-1.30.2
Patch foraging water rate 0 sec1.83.04.32.01.92.0-2.02.02.0-1.92.1-1.71.7-1.7-1.91.91.91.9-2.01.51.61.81.7-1.6-1.6-1.4-1.41.01.0-0.3
Patch foraging water rate 12 sec1.32.04.81.51.31.5-1.51.61.9-1.81.5-0.70.7-0.7-1.71.91.62.0-1.90.91.52.21.2-1.3-0.8-1.1-1.10.40.9-0.5
Patch foraging water rate 18 sec1.72.35.31.20.81.7-1.71.71.7-1.61.7-0.80.8-0.8-1.81.61.81.3-1.5-0.31.12.31.7-1.6-1.9-1.9-1.9-1.10.91.6
Patch foraging water rate 24 sec0.71.06.30.8-0.00.7-0.70.60.8-0.80.8-0.20.2-0.2-0.70.70.70.6-0.7-1.00.41.31.3-1.0-1.7-1.3-1.3-1.50.82.5
Patch foraging water rate 6 sec1.31.93.01.71.01.3-1.31.41.6-1.61.3-1.21.2-1.2-1.31.71.31.7-1.60.31.41.41.1-1.7-1.0-1.7-1.7-0.21.50.1
Seeking ratio, delayed vs. immediate footshock0.10.10.30.10.30.3-0.30.20.1-0.10.30.2-0.20.2-0.10.30.10.3-0.30.50.00.30.20.1-0.40.30.30.6-0.2-0.1
Distance traveled before self-admin0.50.51.8-0.3-0.6-0.70.7-0.5-0.30.3-0.8-0.10.1-0.10.6-0.2-0.6-0.20.0-1.2-0.1-0.9-0.7-0.50.1-1.2-1.2-1.41.31.1
Distance traveled after self-admin0.20.21.30.4-0.10.1-0.10.10.5-0.40.10.1-0.10.1-0.10.50.00.4-0.5-0.50.50.50.1-0.7-0.2-0.9-0.9-0.81.10.7
Extensor digitorum longus weight4.618.223.14.44.64.7-4.74.74.7-4.74.7-4.44.4-4.4-4.74.74.74.7-4.73.74.83.84.4-4.2-4.2-3.4-3.42.53.7-0.2
Bone: elastic displacement0.30.31.2-0.5-0.1-0.50.5-0.5-0.50.5-0.60.3-0.30.30.5-0.5-0.5-0.40.30.4-0.2-0.40.10.80.31.11.10.7-0.9-0.4
Bone: elastic work1.11.53.71.41.61.2-1.21.21.2-1.21.0-1.41.4-1.4-1.21.21.21.1-1.21.91.40.71.5-0.5-1.00.00.01.90.1-1.1
Bone: endosteal estimation3.27.111.02.93.02.9-2.92.92.9-2.92.9-3.33.3-3.3-2.92.82.92.7-2.82.42.61.92.1-2.5-2.1-2.3-2.31.72.2-1.0
Bone: endosteal perimeter1.43.06.72.12.11.7-1.71.71.7-1.71.7-2.62.6-2.6-1.71.71.71.4-1.61.91.60.60.8-1.5-0.6-1.3-1.31.61.1-2.0
Epididymis fat weight0.71.75.2-0.7-0.2-1.11.1-1.0-1.11.1-1.10.3-0.30.31.2-1.2-1.2-1.41.30.8-1.1-1.6-1.01.51.72.12.11.5-2.3-2.2
Delta time in closed arm before/after self-admin0.60.61.7-0.8-0.7-1.11.1-1.0-0.80.8-1.00.3-0.30.31.0-0.7-1.0-0.80.7-0.5-0.7-1.3-1.00.60.80.40.4-0.20.1-0.0
Delta time in open arm before/after self-admin0.80.72.40.60.51.3-1.31.20.8-0.81.3-0.10.1-0.1-1.00.70.90.6-0.50.10.51.61.2-0.7-1.3-0.7-0.7-0.4-0.00.9
Diff in mean of infusions in LGA sessions0.80.92.2-1.3-0.4-0.30.3-0.4-1.21.0-0.40.8-0.80.80.6-1.2-0.7-1.11.00.2-0.9-0.4-0.91.31.01.41.40.6-1.5-1.0
Delay discount exponential model param0.10.10.6-0.0-0.2-0.20.2-0.3-0.40.4-0.1-0.10.1-0.10.4-0.3-0.4-0.30.2-0.2-0.1-0.8-0.30.10.1-0.1-0.1-0.10.30.1
Extinction: sum of active levers before priming0.30.31.7-0.6-0.7-0.10.1-0.0-0.20.3-0.10.9-0.90.90.2-0.1-0.2-0.10.2-0.9-0.30.4-0.3-0.0-0.3-0.3-0.3-1.10.51.3
Active lever presses in extinction session 60.50.51.8-0.4-0.1-0.10.1-0.1-0.30.3-0.10.9-0.90.90.4-0.5-0.3-0.40.30.5-0.60.4-0.31.00.71.31.30.8-1.2-1.0
Bone: final force1.62.64.82.22.01.6-1.61.61.7-1.71.7-2.12.1-2.1-1.61.61.61.6-1.71.91.70.71.1-1.3-0.8-0.9-0.91.61.2-1.4
Bone: final moment2.43.97.62.82.52.1-2.12.12.1-2.12.1-2.42.4-2.4-2.12.12.12.1-2.22.32.01.11.7-1.5-1.3-1.1-1.11.91.3-1.4
Food consumed during 24 hour testing period2.63.14.52.11.91.9-1.91.91.9-1.91.9-1.41.4-1.4-1.91.91.91.9-2.11.72.01.82.1-1.8-1.8-1.4-1.41.31.6-0.1
Glucose0.00.00.10.30.0-0.00.0-0.0-0.10.1-0.0-0.20.2-0.20.1-0.1-0.1-0.10.00.0-0.1-0.3-0.1-0.0-0.0-0.2-0.20.00.2-0.0
Heart weight1.42.03.51.91.61.7-1.71.71.7-1.71.7-1.11.1-1.1-1.61.61.61.4-1.31.51.21.71.6-1.0-1.3-0.6-0.61.10.3-0.5
Delay discount hyperbolic model param0.00.00.40.0-0.1-0.20.2-0.2-0.30.3-0.1-0.10.1-0.10.3-0.3-0.3-0.20.1-0.1-0.1-0.6-0.20.10.10.00.0-0.00.2-0.1
Intermittent access intake day 1-15 change1.81.75.5-1.8-1.7-1.11.1-1.1-1.11.2-1.22.3-2.32.31.1-1.2-1.1-1.11.0-1.6-0.8-0.0-0.90.90.90.70.7-1.4-0.51.1
Intermittent access intake escalation1.31.34.7-1.7-1.4-0.90.9-0.8-1.01.0-1.02.2-2.22.20.9-1.0-0.9-0.80.8-1.3-0.60.1-0.80.70.80.60.6-1.2-0.40.9
Intermittent access intake escalation 20.60.62.6-1.1-1.0-0.40.4-0.4-0.50.6-0.41.6-1.61.60.5-0.7-0.4-0.50.4-1.2-0.20.5-0.30.20.20.00.0-1.20.21.2
Intermitt. access day 1 inactive lever presses0.30.30.7-0.8-0.7-0.60.6-0.6-0.60.5-0.60.3-0.30.30.7-0.5-0.7-0.50.4-0.8-0.4-0.5-0.60.20.2-0.1-0.1-0.80.20.8
Intermitt. access day 15 inactive lever presses0.50.52.4-1.0-0.30.1-0.10.00.2-0.2-0.11.5-1.51.5-0.10.10.10.1-0.10.00.01.5-0.10.50.80.90.90.1-0.7-0.3
Intermitt. access escalation Index0.40.40.9-0.5-0.4-0.40.4-0.5-0.80.8-0.50.1-0.10.10.7-0.9-0.7-0.91.0-0.2-0.8-0.8-0.40.70.30.70.70.1-0.8-0.2
Intermittent access day 1 total infusions1.92.23.31.21.71.6-1.61.61.7-1.61.5-1.81.8-1.8-1.51.71.51.8-1.61.51.41.21.2-1.4-1.2-1.1-1.11.11.2-0.6
Intermittent access day 15 total infusions0.30.31.0-0.20.40.7-0.70.70.6-0.60.5-0.20.2-0.2-0.60.60.60.8-0.70.20.60.90.2-0.8-0.3-0.7-0.7-0.11.00.2
Intermittent access terminal intake (last 3 days)0.30.31.3-0.50.40.6-0.60.70.6-0.60.50.2-0.20.2-0.60.50.60.7-0.80.40.71.10.2-0.7-0.2-0.5-0.50.20.8-0.0
Intermittent access total infusions2.12.33.80.91.51.8-1.81.81.8-1.81.6-1.11.1-1.1-1.81.81.81.9-1.81.21.61.91.3-1.6-1.3-1.4-1.40.71.6-0.0
Intermittent access day 1 locomotion0.30.31.3-0.10.4-0.10.1-0.1-0.00.1-0.2-0.70.7-0.70.2-0.1-0.20.00.10.9-0.3-0.8-0.30.40.40.50.51.1-0.4-1.2
Intermittent access day 15 total locomotion0.10.10.6-0.50.2-0.10.1-0.0-0.10.1-0.3-0.10.1-0.10.20.1-0.20.2-0.10.50.0-0.60.00.10.30.30.30.8-0.2-0.7
Intermittent access total locomotion0.20.20.8-0.10.60.3-0.30.40.2-0.20.2-0.60.6-0.6-0.10.20.10.4-0.40.80.3-0.40.1-0.30.0-0.1-0.10.90.2-0.7
Intermittent access standard deviation0.50.62.7-0.7-0.60.1-0.10.30.2-0.20.11.6-1.61.6-0.40.20.4-0.00.1-1.0-0.01.6-0.10.10.2-0.0-0.0-1.2-0.20.9
Left kidney weight3.49.513.43.03.43.7-3.73.63.5-3.53.6-3.33.3-3.3-3.43.33.43.2-3.02.62.92.93.0-2.9-3.3-2.6-2.61.62.0-0.1
Right kidney weight3.59.914.13.03.43.6-3.63.83.6-3.73.7-3.13.1-3.1-3.63.43.53.2-3.12.63.13.23.2-3.1-3.3-2.8-2.81.62.0-0.0
Cocaine induced anxiety1.01.13.2-0.7-1.0-1.11.1-1.1-1.21.2-1.20.5-0.50.51.3-1.3-1.3-1.21.3-0.9-1.3-1.8-1.51.01.40.50.5-0.6-0.7-0.3
Post-drug Anxiety0.40.52.4-0.0-0.5-0.90.9-0.9-0.70.7-1.0-0.00.0-0.00.7-0.8-0.7-0.70.8-0.4-0.7-1.6-1.00.60.80.30.3-0.1-0.2-0.2
Baseline Anxiety0.50.61.40.60.70.5-0.50.50.9-0.90.6-0.20.2-0.2-1.00.91.00.9-1.00.71.11.21.0-0.7-0.9-0.4-0.40.60.70.3
Tail length1.13.410.12.12.51.8-1.81.61.9-1.91.8-1.51.5-1.5-1.91.81.91.8-1.93.22.11.51.6-1.0-0.7-0.1-0.13.20.4-2.6
Length with tail2.810.316.33.74.03.6-3.63.53.6-3.73.5-3.03.0-3.0-3.63.73.63.5-3.54.03.53.23.3-2.2-2.5-1.2-1.23.41.3-1.9
Length without tail2.35.18.82.32.22.7-2.72.82.7-2.92.6-1.91.9-1.9-2.62.82.62.5-2.31.42.23.02.7-1.7-2.6-1.5-1.50.50.90.8
Times rat made contact with spout0.20.31.20.60.60.4-0.40.40.4-0.40.4-0.10.1-0.1-0.50.40.40.2-0.61.00.50.60.5-0.1-0.00.40.41.1-0.2-1.1
Lifetime Intake2.32.64.30.91.61.9-1.91.91.9-1.91.7-1.21.2-1.2-1.81.91.82.0-1.91.21.82.11.4-1.8-1.4-1.5-1.50.71.6-0.0
Liver weight, left0.91.49.40.60.90.0-0.00.1-0.00.0-0.10.0-0.00.0-0.00.0-0.0-0.0-0.22.30.2-0.1-0.11.31.22.12.13.0-1.1-3.1
Liver weight, right0.40.63.20.40.90.7-0.70.70.7-0.70.60.0-0.00.0-0.60.70.70.5-0.31.60.21.00.40.40.00.80.81.8-1.1-1.6
Locomotor activity0.91.42.9-0.3-1.2-1.01.0-1.2-1.31.3-1.01.2-1.21.21.3-1.4-1.3-1.41.4-1.0-1.6-1.2-1.01.71.01.31.3-0.6-1.5-0.3
Locomotor testing distance0.61.12.4-0.2-1.0-0.80.8-1.1-1.11.1-0.90.7-0.70.71.4-1.1-1.4-1.11.1-0.7-1.5-1.4-0.61.60.51.31.3-0.3-1.30.1
Locomotor testing rearing0.81.32.5-0.4-1.3-0.80.8-1.1-1.31.3-0.91.0-1.01.01.5-1.2-1.5-1.31.3-1.2-1.6-1.1-0.61.60.51.31.3-0.9-1.60.5
Locomotion in novel chamber0.20.21.40.00.3-0.30.3-0.2-0.20.3-0.3-1.01.0-1.00.1-0.2-0.2-0.0-0.00.40.1-1.20.1-0.3-0.2-0.2-0.20.60.5-0.2
Locomotion in novel chamber post-restriction1.11.32.4-0.7-0.9-1.41.4-1.6-1.01.1-1.41.1-1.11.11.2-1.2-1.3-1.21.2-0.4-1.1-1.4-1.11.21.31.31.30.2-1.1-0.6
Fecal boli incidents, locomotor time 10.20.21.50.10.2-0.40.4-0.3-0.10.1-0.4-0.20.2-0.20.1-0.0-0.10.00.00.60.0-0.4-0.30.20.80.50.50.9-0.6-1.2
Change in fecal boli incidents, locomotor task0.30.31.10.30.20.2-0.20.0-0.00.00.10.3-0.30.30.1-0.3-0.1-0.40.30.6-0.50.10.10.90.11.11.10.8-1.1-0.6
Time >=10cm from walls, locomotor time 11.01.03.70.70.80.8-0.80.91.3-1.30.8-0.10.1-0.1-1.21.41.21.4-1.50.61.51.91.3-1.1-0.6-0.7-0.70.40.8-0.0
Bouts of movement, locomotor time 10.40.50.8-0.6-0.7-0.80.8-0.8-0.90.9-0.90.5-0.50.50.7-0.7-0.7-0.70.7-0.6-0.8-0.7-0.70.70.80.60.6-0.3-0.9-0.0
Total resting periods, locomotor time 10.30.31.4-0.3-0.2-0.50.5-0.5-0.60.6-0.50.2-0.20.20.5-0.5-0.5-0.50.50.2-0.6-0.5-0.50.70.80.80.80.5-1.2-0.8
Rest time, locomotor task time 10.50.61.7-0.8-0.6-0.50.5-0.6-0.70.7-0.50.7-0.70.70.5-0.7-0.5-0.80.9-0.3-1.1-0.4-1.10.91.10.90.9-0.0-1.3-0.6
Distance moved, locomotor task time 10.30.41.8-0.1-0.3-0.60.6-0.3-0.20.2-0.6-0.50.5-0.50.5-0.4-0.5-0.30.3-0.8-0.1-1.1-0.2-0.5-0.3-0.9-0.9-0.91.30.9
Vertical activity count, locomotor time 10.30.31.30.1-0.6-0.40.4-0.2-0.60.5-0.40.0-0.00.00.5-0.7-0.5-0.50.5-1.0-0.3-0.9-0.1-0.3-0.2-0.7-0.7-1.20.71.0
Time >=10cm from walls, locomotor time 22.72.84.31.91.91.7-1.71.72.1-2.11.7-1.31.3-1.3-2.12.02.12.0-2.01.82.02.11.9-1.5-1.2-0.9-0.91.40.8-0.8
Bouts of movement, locomotor time 20.20.20.70.10.40.5-0.50.40.4-0.30.4-0.20.2-0.2-0.70.60.70.6-0.50.40.60.90.6-0.5-0.7-0.4-0.40.30.40.4
Total resting periods, locomotor time 20.10.10.40.00.20.2-0.20.20.1-0.10.1-0.10.1-0.1-0.40.40.40.3-0.30.30.30.50.5-0.2-0.6-0.1-0.10.20.10.4
Rest time, locomotor task time 20.91.02.1-1.4-0.9-1.01.0-0.9-1.21.2-1.10.8-0.80.80.9-1.1-0.9-1.21.2-0.5-1.2-0.9-1.21.21.21.11.1-0.1-1.2-0.4
Distance moved, locomotor task time 20.50.63.20.1-0.8-0.50.5-0.5-0.30.3-0.40.1-0.10.10.7-0.4-0.7-0.30.3-1.6-0.3-0.9-0.4-0.6-0.3-1.1-1.1-1.81.41.5
Vertical activity count, locomotor time 20.70.72.41.30.10.5-0.50.60.5-0.50.5-0.70.7-0.7-0.40.40.40.5-0.5-0.70.60.20.8-1.3-1.0-1.6-1.6-1.21.51.3
Light reinforcement 11.73.06.01.41.31.7-1.71.71.6-1.61.5-2.12.1-2.1-1.61.51.61.7-1.60.11.71.01.6-2.3-2.1-2.4-2.4-0.62.41.4
Light reinforcement 22.43.34.81.21.71.9-1.91.91.9-1.81.8-2.12.1-2.1-1.91.71.91.9-1.90.92.01.51.8-2.2-2.1-2.0-2.00.22.10.9
Bone: marrow area3.27.011.13.03.02.9-2.92.92.9-2.92.9-3.33.3-3.3-2.92.82.92.8-2.72.42.61.82.1-2.5-2.1-2.3-2.31.72.2-1.0
Bone: maximum diameter3.15.78.82.93.02.5-2.52.52.5-2.52.5-2.92.9-2.9-2.52.52.52.5-2.53.02.41.72.1-1.8-1.6-1.3-1.32.61.3-1.8
Bone: maximum force2.44.27.82.82.42.2-2.22.22.3-2.32.3-2.52.5-2.5-2.22.22.22.0-2.02.02.01.31.6-1.8-1.4-1.5-1.51.51.2-1.3
Bone: maximum moment3.15.310.53.22.82.5-2.52.52.5-2.52.6-2.72.7-2.7-2.52.52.52.4-2.42.42.21.62.1-1.8-1.8-1.5-1.51.91.3-1.3
Mean time between licks in bursts0.30.42.10.30.50.4-0.40.40.5-0.50.4-0.80.8-0.8-0.50.50.40.3-1.00.31.00.20.2-0.9-0.3-0.8-0.80.11.4-0.1
Mean num. licks in bursts0.30.31.21.10.60.7-0.70.70.6-0.60.8-0.20.2-0.2-0.70.60.70.5-0.30.60.30.80.3-0.1-0.1-0.0-0.00.5-0.3-0.9
Cd content in liver0.30.30.90.20.50.4-0.40.40.4-0.40.4-0.90.9-0.9-0.40.40.40.3-0.60.20.8-0.10.2-1.0-0.2-0.9-0.9-0.01.0-0.2
Co content in liver0.40.51.21.10.90.7-0.70.70.7-0.70.7-0.80.8-0.8-0.70.70.70.8-0.81.00.70.50.6-0.3-0.3-0.0-0.01.00.2-1.0
Cu content in liver0.50.61.4-0.8-0.5-0.90.9-0.9-0.80.8-0.80.8-0.80.80.8-0.7-0.8-0.60.60.1-0.6-0.8-0.90.91.21.11.10.5-0.5-0.9
Fe content in liver0.91.05.11.01.30.8-0.80.80.8-0.80.7-0.30.3-0.3-0.80.80.80.9-0.72.00.70.80.90.10.00.80.82.3-0.9-2.2
K content in liver2.02.02.8-1.2-1.5-1.51.5-1.5-1.41.4-1.41.5-1.51.51.4-1.5-1.4-1.61.6-1.2-1.7-1.0-1.51.61.61.41.4-0.8-1.4-0.3
Mg content in liver0.20.20.6-0.0-0.4-0.40.4-0.4-0.40.4-0.30.4-0.40.40.4-0.4-0.4-0.60.6-0.3-0.8-0.3-0.40.70.30.50.5-0.2-0.8-0.1
Mn content in liver0.00.10.60.30.20.1-0.10.10.0-0.00.0-0.10.1-0.1-0.0-0.10.0-0.1-0.00.3-0.1-0.1-0.10.20.30.30.30.4-0.3-0.8
Na content in liver2.12.23.6-1.5-1.4-1.41.4-1.4-1.41.4-1.41.6-1.61.61.4-1.4-1.4-1.61.7-0.9-1.7-0.9-1.71.61.91.61.6-0.4-1.9-1.0
Rb content in liver0.30.42.40.6-0.2-0.30.3-0.3-0.30.3-0.30.5-0.50.50.3-0.4-0.3-0.40.90.1-0.9-0.1-0.01.00.30.90.90.4-1.5-0.4
Se content in liver2.83.45.1-2.1-1.8-1.91.9-1.9-1.91.9-1.92.0-2.02.01.9-1.8-1.9-2.21.9-1.1-1.9-1.4-1.92.22.32.12.1-0.5-2.1-0.8
Sr content in liver4.74.38.3-2.9-2.3-2.32.3-2.3-2.32.3-2.32.3-2.32.32.3-2.3-2.3-2.31.8-1.9-1.8-1.8-2.21.92.11.71.7-1.3-1.20.3
Zn content in liver0.40.42.00.50.50.5-0.50.50.5-0.50.5-0.70.7-0.7-0.50.50.50.6-1.20.10.80.30.6-0.7-0.7-0.6-0.6-0.11.40.5
Bone: minimum diameter1.32.53.81.81.71.7-1.71.71.8-1.81.8-1.91.9-1.9-1.71.81.71.8-1.81.31.51.31.1-1.3-1.0-1.2-1.20.81.2-0.9
Time in familiar zone, hab. session 10.90.91.40.91.11.0-1.01.01.0-1.01.0-1.21.2-1.2-1.00.91.00.8-0.91.00.90.60.9-0.9-0.8-0.8-0.80.70.4-0.4
Time in novel zone, hab. session 13.23.16.6-1.7-2.3-1.81.8-1.8-1.81.8-1.82.0-2.02.01.8-1.8-1.8-1.81.9-2.6-2.0-1.2-1.61.40.90.80.8-2.4-0.82.0
Total zone transitions, hab. session 16.69.314.8-3.6-2.9-3.13.1-3.1-3.03.1-3.13.8-3.83.83.1-3.1-3.1-3.03.0-1.6-2.9-1.9-2.83.53.33.53.5-0.5-3.0-0.7
Total locomotion distance, hab. session 14.97.012.9-3.0-2.1-2.62.6-2.6-2.62.5-2.63.0-3.03.02.6-2.6-2.6-2.42.5-0.6-2.3-1.6-2.53.23.33.63.60.6-3.2-1.8
Locomotion velocity, hab. session 13.24.69.9-2.5-1.4-2.02.0-2.0-1.91.9-2.02.5-2.52.52.0-1.9-1.9-1.71.80.1-1.6-1.0-1.92.62.93.13.11.2-2.8-2.2
Time in familiar zone, hab. session 20.20.21.0-0.10.20.6-0.60.60.6-0.50.6-0.00.0-0.0-0.60.60.60.4-0.5-0.20.41.00.2-0.6-0.2-0.8-0.8-0.50.20.0
Time in novel zone, hab. session 20.40.41.70.2-0.5-0.70.7-0.7-0.80.7-0.7-0.00.0-0.00.7-0.8-0.7-0.70.8-0.4-0.8-1.3-0.30.80.10.70.7-0.2-0.30.7
Total zone transitions, hab. session 23.95.17.9-2.8-2.6-2.52.5-2.5-2.52.5-2.52.5-2.52.52.5-2.3-2.5-2.32.2-2.2-2.2-1.9-2.61.92.41.51.5-1.6-1.20.3
Total locomotion distance, hab. session 21.62.15.1-1.9-1.2-1.51.5-1.5-1.51.4-1.51.3-1.31.31.5-1.4-1.5-1.31.1-0.3-1.1-1.1-1.81.52.31.61.60.3-1.3-1.6
Locomotion velocity, hab. session 21.21.64.6-1.7-0.9-1.31.3-1.3-1.21.2-1.31.2-1.21.21.3-1.1-1.3-1.00.80.0-0.8-0.9-1.61.32.21.51.50.6-1.1-1.8
Novel to familiar place preference ratio0.50.53.30.20.4-0.40.4-0.4-0.30.3-0.4-0.10.1-0.10.4-0.2-0.4-0.10.01.3-0.0-0.8-0.10.80.61.41.41.8-0.5-1.4
Novelty place preference0.80.83.4-0.10.0-0.80.8-0.8-0.70.7-0.80.3-0.30.30.8-0.6-0.8-0.50.41.1-0.4-1.1-0.31.30.91.81.81.7-0.9-1.4
Time in novel zone, NPP test0.91.03.9-0.1-0.1-0.90.9-0.9-0.80.8-0.90.4-0.40.40.9-0.7-0.9-0.70.50.9-0.5-1.2-0.51.51.02.02.01.5-1.0-1.3
Total zone transitions, NPP test2.94.28.7-3.0-2.5-2.22.2-2.2-2.22.2-2.22.3-2.32.32.2-2.3-2.2-2.22.0-2.4-2.0-1.6-2.01.41.60.90.9-2.0-0.81.3
Total locomotion distance, NPP test1.21.64.5-2.1-1.4-1.51.5-1.5-1.41.4-1.51.2-1.21.21.5-1.5-1.5-1.41.1-1.1-1.1-1.3-1.60.91.50.70.7-0.7-0.6-0.0
Locomotion velocity, NPP test0.81.14.2-2.0-1.0-1.21.2-1.2-1.11.1-1.20.9-0.90.91.2-1.2-1.2-1.10.9-0.8-0.8-1.1-1.40.61.30.50.5-0.5-0.4-0.2
Intraocular pressure0.71.02.51.51.31.0-1.01.10.8-0.81.1-1.41.4-1.4-0.90.60.90.7-0.71.60.60.10.9-0.5-0.6-0.4-0.41.50.2-1.0
Delta distance traveled before/after self-admin0.50.63.10.60.51.1-1.10.81.0-0.91.10.3-0.30.3-1.00.80.90.7-0.60.60.61.81.0-0.3-0.80.10.10.40.00.0
Delta ambulatory time before/after self-admin0.20.21.40.10.00.5-0.50.30.3-0.30.60.6-0.60.6-0.30.30.30.1-0.00.20.11.20.50.2-0.30.40.40.1-0.40.1
Parametrial fat weight0.40.71.6-0.7-1.1-0.60.6-0.6-0.70.7-0.71.1-1.11.10.6-0.7-0.6-0.90.9-1.3-0.70.2-0.40.90.41.01.0-1.2-0.70.8
Pavlov. Cond. lever latency0.20.30.70.1-0.7-0.50.5-0.5-0.50.4-0.50.5-0.50.50.4-0.4-0.4-0.40.7-0.8-0.8-0.3-0.50.60.50.20.2-0.8-0.70.4
Pavlov. Cond. magazine entry latency0.60.84.2-0.70.1-0.50.5-0.5-0.60.6-0.5-0.00.0-0.00.6-0.6-0.6-0.70.51.0-0.4-1.0-0.91.01.31.51.51.5-1.1-2.1
Pavlov. Cond. change in total contacts0.50.61.5-1.2-0.6-0.80.8-0.8-0.80.8-0.80.4-0.40.40.9-0.8-0.8-1.10.7-0.2-0.8-0.9-0.90.80.90.80.80.1-0.7-0.6
Pavlov. Cond. index score0.20.21.7-0.60.3-0.20.2-0.2-0.20.2-0.2-0.20.2-0.20.3-0.2-0.2-0.30.00.80.1-0.6-0.40.30.60.70.71.1-0.2-1.3
Pavlov. Cond. latency score0.20.21.8-0.40.5-0.10.1-0.1-0.00.1-0.1-0.40.4-0.40.1-0.1-0.1-0.1-0.21.00.2-0.5-0.20.20.40.60.61.2-0.0-1.3
Pavlov. Cond. lever contacts0.20.30.9-0.00.70.4-0.40.40.4-0.40.4-0.60.6-0.6-0.40.40.40.3-0.60.90.70.10.5-0.5-0.5-0.2-0.21.00.6-0.5
Pavlov. Cond. magazine entry number0.40.52.40.5-0.20.5-0.50.50.5-0.50.50.4-0.40.4-0.50.50.50.5-0.3-0.80.21.20.8-0.6-0.9-1.0-1.0-1.20.31.5
Pavlov. Cond. intertrial magazine entries0.60.72.4-0.7-1.2-0.50.5-0.5-0.50.4-0.51.5-1.51.50.5-0.5-0.5-0.70.6-1.4-0.60.7-0.10.60.10.30.3-1.5-0.71.3
Pavlov. Cond. lever-magazine prob. diff.0.20.21.4-0.60.3-0.20.2-0.2-0.20.2-0.2-0.20.2-0.20.2-0.2-0.2-0.3-0.00.70.1-0.5-0.30.30.50.60.61.0-0.2-1.2
Pavlov. Cond. response bias0.20.21.3-0.40.3-0.20.2-0.2-0.20.2-0.2-0.40.4-0.40.2-0.1-0.2-0.2-0.00.80.1-0.6-0.20.20.30.50.51.1-0.1-1.0
Pavlov. Cond. lever latency0.60.83.2-0.3-0.7-0.80.8-0.8-0.80.8-0.80.7-0.70.70.8-0.9-0.8-1.11.3-0.4-1.4-0.7-0.51.40.41.41.4-0.1-1.80.1
Pavlov. Cond. magazine entry latency0.50.51.2-1.0-0.8-0.80.8-0.8-0.80.8-0.81.0-1.01.00.8-0.8-0.8-0.60.4-0.6-0.5-0.4-0.90.51.10.30.3-0.4-0.1-0.4
Pavlov. Cond. change in total contacts0.50.72.10.10.60.7-0.70.70.7-0.70.7-0.50.5-0.5-0.70.70.70.9-1.10.21.00.60.6-1.3-0.7-1.5-1.5-0.11.40.4
Pavlov. Cond. index score0.20.21.3-0.20.20.3-0.30.30.3-0.30.3-0.00.0-0.0-0.30.40.30.6-0.80.10.80.50.1-0.80.0-0.9-0.9-0.01.1-0.1
Pavlov. Cond. latency score0.50.72.00.30.70.7-0.70.70.8-0.80.7-0.50.5-0.5-0.70.90.71.0-1.20.61.20.80.6-1.1-0.4-1.1-1.10.41.4-0.3
Pavlov. Cond. lever contacts0.60.82.50.30.70.8-0.80.80.9-0.90.8-0.60.6-0.6-0.80.90.81.0-1.30.51.40.90.6-1.3-0.4-1.3-1.30.21.6-0.2
Pavlov. Cond. magazine entry number0.20.20.60.80.60.4-0.40.40.4-0.40.4-0.60.6-0.6-0.40.30.40.20.00.60.00.00.50.2-0.40.50.50.6-0.6-0.3
Pavlov. Cond. intertrial magazine entries0.40.52.31.10.70.7-0.70.70.7-0.70.8-0.10.1-0.1-0.70.60.70.5-0.11.00.01.10.90.3-0.40.60.61.0-1.5-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.21.3-0.30.20.3-0.30.30.3-0.30.30.0-0.00.0-0.30.40.30.5-0.80.00.70.60.1-0.80.0-0.9-0.9-0.11.1-0.1
Pavlov. Cond. response bias0.20.21.5-0.4-0.00.1-0.10.10.2-0.20.10.1-0.10.1-0.10.20.10.3-0.6-0.30.70.4-0.2-0.80.2-1.0-1.0-0.41.20.0
Time in closed arm before self-admin1.31.54.61.91.20.8-0.80.81.1-1.00.8-2.12.1-2.1-0.91.00.91.1-1.10.61.1-0.40.9-1.5-1.0-1.6-1.60.31.30.0
Time in closed arm after self-admin0.50.53.50.3-0.0-0.90.9-0.8-0.40.4-0.8-1.01.0-1.00.5-0.4-0.5-0.40.3-0.1-0.4-1.9-0.8-0.00.6-0.2-0.20.10.6-0.5
Time in open arm before self-admin0.20.20.9-0.90.1-0.40.4-0.5-0.10.1-0.50.1-0.10.10.4-0.1-0.30.0-0.10.60.0-0.4-0.60.40.70.60.61.00.2-0.9
Time in open arm after self-admin0.30.42.2-0.20.21.0-1.00.80.5-0.50.90.6-0.60.6-0.50.50.50.4-0.30.20.31.50.9-0.2-0.9-0.1-0.1-0.1-0.30.7
Bone: periosteal estimation4.49.014.03.43.53.2-3.23.23.2-3.23.2-3.73.7-3.7-3.23.23.23.3-3.23.03.12.22.5-2.6-2.3-2.3-2.32.22.4-1.4
Bone: periosteal perimeter4.57.512.33.33.32.9-2.92.92.9-2.92.9-3.53.5-3.5-2.92.92.92.7-2.83.12.71.82.1-2.3-1.7-1.8-1.82.51.5-2.2
Bone: post-yield work1.21.63.61.91.51.4-1.41.41.5-1.51.4-1.31.3-1.3-1.41.51.41.3-1.01.40.61.21.2-0.7-1.1-0.6-0.61.1-0.2-0.9
Progressive ratio test 1 active lever presses2.52.68.60.61.72.1-2.12.11.9-1.92.0-0.50.5-0.5-1.91.91.91.9-2.01.61.92.91.3-1.4-0.8-0.9-0.91.10.7-0.8
Progressive ratio test 1 breakpoint2.32.48.50.51.62.0-2.02.01.8-1.81.9-0.40.4-0.4-1.91.81.81.8-1.91.61.82.91.2-1.3-0.8-0.7-0.71.10.5-0.8
Progressive ratio test 1 inactive lever presses0.30.42.4-0.30.20.7-0.70.70.5-0.50.70.8-0.80.8-0.40.60.40.7-0.70.40.61.50.6-0.2-0.20.20.20.3-0.3-0.1
Progressive ratio test 2 active lever presses0.91.01.50.61.11.2-1.21.21.1-1.11.2-1.11.1-1.1-1.01.11.01.1-1.00.90.90.80.8-1.0-1.1-1.0-1.00.50.80.0
Progressive ratio test 2 breakpoint1.01.11.70.81.21.3-1.31.31.2-1.11.2-1.21.2-1.2-1.01.21.11.2-1.01.01.00.80.9-1.1-1.1-1.0-1.00.60.8-0.0
Progressive ratio test 2 inactive lever presses0.00.10.3-0.4-0.1-0.10.1-0.10.2-0.1-0.10.5-0.50.5-0.00.20.00.3-0.2-0.10.10.4-0.0-0.10.1-0.0-0.0-0.10.10.2
Incentive Sensitization - Responses0.20.20.70.40.30.3-0.30.40.1-0.10.3-0.80.8-0.80.10.2-0.10.10.00.0-0.1-0.70.3-0.2-0.8-0.5-0.5-0.10.40.6
Incentive Sensitization - Breakpoint0.40.41.20.70.50.6-0.60.60.4-0.30.5-1.11.1-1.1-0.10.40.20.4-0.20.20.2-0.50.6-0.5-1.1-0.7-0.70.00.60.7
Sum of active levers in priming session hrs 5-60.30.30.70.50.50.7-0.70.80.5-0.70.7-0.40.4-0.4-0.70.30.60.3-0.40.20.40.80.5-0.5-0.6-0.6-0.6-0.10.30.3
Progressive ratio0.30.42.00.10.1-0.70.7-0.7-0.50.4-0.6-0.70.7-0.70.4-0.5-0.4-0.50.50.4-0.5-1.4-0.80.30.80.30.30.6-0.2-1.0
Food seeking constrained by brief footshock16.019.730.84.34.55.4-5.45.45.2-5.15.3-3.63.6-3.6-5.25.05.25.1-4.93.24.65.64.7-4.3-4.3-3.6-3.61.63.00.1
Seeking ratio, punishment vs. effort6.07.417.22.22.33.5-3.53.53.2-3.13.3-1.31.3-1.3-3.13.13.13.2-3.11.33.04.13.2-2.6-3.0-2.2-2.20.32.01.1
Retroperitoneal fat weight0.31.12.8-1.5-1.1-0.90.9-0.7-0.80.7-1.01.3-1.31.30.8-1.0-0.8-1.31.4-0.8-1.20.2-1.01.20.91.21.2-0.6-1.70.3
Reaction time number correct0.20.31.51.20.60.0-0.00.20.4-0.3-0.0-1.21.2-1.2-0.20.40.20.2-0.40.50.2-0.7-0.0-0.20.1-0.0-0.00.50.7-0.6
Reaction time mean minus median0.71.02.6-0.9-1.2-0.90.9-0.8-0.90.9-0.81.6-1.61.60.9-0.9-0.9-0.91.0-1.0-1.1-0.1-0.90.90.90.50.5-0.9-1.10.2
Reaction time mean minus median AUC0.50.61.5-0.6-1.0-0.80.8-0.6-0.80.7-0.71.2-1.21.20.7-0.6-0.7-0.70.8-0.9-0.7-0.2-0.80.50.80.20.2-0.8-0.60.2
Reaction time num false alarms0.30.42.0-0.3-0.3-0.40.4-0.4-0.40.4-0.5-0.80.8-0.80.6-0.5-0.6-0.50.4-0.8-0.5-1.3-0.2-0.1-0.6-0.6-0.6-0.90.71.4
Reaction time num false alarms AUC0.20.31.5-0.2-0.0-0.00.0-0.1-0.20.2-0.1-0.90.9-0.90.2-0.4-0.2-0.30.3-0.4-0.4-0.80.1-0.1-0.9-0.6-0.6-0.60.51.2
Reaction time trials correct on left0.20.31.51.20.60.0-0.00.20.4-0.3-0.0-1.21.2-1.2-0.20.40.20.2-0.40.50.2-0.7-0.0-0.20.1-0.0-0.00.50.7-0.6
Reaction time trials on left0.30.41.81.30.70.1-0.10.20.4-0.40.0-1.31.3-1.3-0.30.50.30.2-0.50.60.3-0.70.0-0.20.1-0.1-0.10.60.7-0.7
Reaction time mean0.00.00.20.20.10.3-0.30.40.0-0.00.5-0.10.1-0.1-0.10.30.00.3-0.10.10.10.20.1-0.1-0.3-0.2-0.20.0-0.1-0.1
Reaction time mean AUC0.10.10.30.10.30.4-0.40.40.1-0.10.5-0.00.0-0.0-0.10.40.10.4-0.20.30.30.40.2-0.2-0.2-0.1-0.10.3-0.3-0.3
Median of all reaction times0.20.30.90.50.70.8-0.80.80.3-0.30.9-0.70.7-0.7-0.50.50.40.6-0.40.60.60.30.4-0.5-0.5-0.4-0.40.50.2-0.4
Reaction time omissions0.30.42.30.70.90.5-0.50.50.5-0.50.6-0.70.7-0.7-0.30.50.30.5-0.41.30.50.10.2-0.10.20.40.41.4-0.3-1.5
Reaction time false alarm rate0.20.31.6-1.0-0.6-0.40.4-0.5-0.60.6-0.40.1-0.10.10.6-0.8-0.6-0.70.8-0.6-0.8-0.6-0.10.4-0.50.00.0-0.6-0.51.3
Reaction time premature initiation rate0.20.31.0-0.2-0.2-0.20.2-0.2-0.70.6-0.2-0.30.3-0.30.4-0.8-0.4-0.60.9-0.0-0.7-1.00.30.6-0.50.60.60.2-0.90.5
Reaction time premature initiations0.20.31.60.70.4-0.00.00.1-0.30.20.0-1.21.2-1.20.1-0.4-0.2-0.30.40.3-0.3-1.30.40.2-0.70.30.30.4-0.20.2
Std. dev. reaction times0.50.71.2-0.8-1.0-0.80.8-0.7-0.90.9-0.71.1-1.11.10.9-0.8-0.9-0.81.0-1.0-1.0-0.4-0.70.70.40.40.4-0.9-0.90.6
Reaction time trials completed0.30.41.81.30.70.1-0.10.20.4-0.40.0-1.31.3-1.3-0.30.50.30.2-0.50.60.3-0.70.0-0.20.1-0.1-0.10.60.7-0.7
Reaction time trials AUC0.30.41.81.30.70.2-0.20.30.5-0.40.1-1.31.3-1.3-0.30.50.30.3-0.60.60.4-0.50.1-0.3-0.1-0.1-0.10.50.8-0.5
Run reversals in cocaine runway, females0.10.11.0-0.70.2-0.10.10.0-0.10.1-0.1-0.40.4-0.40.1-0.1-0.0-0.10.20.4-0.2-0.5-0.60.10.60.10.10.4-0.3-1.0
Run reversals in cocaine runway, males0.30.31.1-0.0-0.6-0.30.3-0.3-0.20.2-0.21.0-1.01.00.1-0.5-0.1-0.40.4-0.6-0.50.5-0.20.60.60.60.6-0.6-0.9-0.0
Latency to leave start box in cocaine runway0.60.62.50.11.20.6-0.60.60.8-0.80.3-1.11.1-1.1-0.80.60.80.6-0.61.50.60.30.7-0.4-0.40.10.11.6-0.4-0.9
Latency to leave start box in cocaine runway, F0.30.31.70.00.80.1-0.10.20.4-0.4-0.1-0.90.9-0.9-0.30.30.30.3-0.31.20.3-0.20.6-0.3-0.30.10.11.3-0.2-0.5
Latency to leave start box in cocaine runway, M0.80.71.30.71.11.1-1.11.11.0-1.01.1-0.70.7-0.7-1.00.81.00.8-0.71.10.81.01.0-0.5-0.8-0.2-0.20.9-0.1-0.5
Std. dev. time between licks in bursts0.60.72.00.70.80.8-0.80.80.8-0.80.8-0.80.8-0.8-0.80.80.80.9-1.20.61.10.60.7-1.0-0.8-0.8-0.80.31.40.1
Total sessions with >9 infusions0.10.10.3-0.50.10.1-0.10.10.3-0.30.10.1-0.10.1-0.20.30.10.3-0.10.00.20.5-0.6-0.30.4-0.4-0.4-0.10.3-0.3
Short access day 1 total inactive lever presses0.20.21.8-0.5-0.5-0.10.1-0.1-0.20.20.00.7-0.70.70.40.0-0.4-0.00.3-0.7-0.40.30.10.1-0.5-0.1-0.1-0.8-0.11.3
Short access day 10 total inactive lever presses0.50.61.3-0.7-1.0-0.80.8-0.9-0.70.7-0.70.8-0.80.80.9-0.7-0.9-0.70.8-1.1-0.8-0.8-0.50.60.30.40.4-1.0-0.51.0
Short access day 1 total infusions0.20.21.0-1.0-0.5-0.20.2-0.2-0.20.2-0.10.8-0.80.80.2-0.2-0.3-0.20.4-0.5-0.40.5-0.60.20.20.10.1-0.5-0.10.4
Short access day 10 total infusions0.91.01.90.61.21.2-1.21.11.1-1.11.1-0.80.8-0.8-1.01.21.01.3-1.31.41.21.20.7-0.9-0.4-0.5-0.51.20.9-1.0
Short access total infusions0.80.92.70.30.91.1-1.11.11.2-1.21.0-0.50.5-0.5-1.11.21.11.3-1.20.81.21.70.7-1.1-0.5-0.8-0.80.50.9-0.3
Short access day 1 locomotion0.80.91.8-1.0-0.4-0.90.9-0.9-0.80.8-0.80.5-0.50.50.9-0.9-0.9-0.90.90.4-1.0-1.1-1.11.11.21.31.31.0-1.1-1.3
Short access day 10 total locomotion0.50.52.50.10.4-0.20.2-0.3-0.30.3-0.1-0.50.5-0.50.3-0.5-0.3-0.50.41.1-0.4-1.1-0.30.80.51.11.11.5-1.0-1.6
Short access total locomotion0.30.32.6-0.50.2-0.20.2-0.2-0.30.3-0.1-0.00.0-0.00.3-0.4-0.3-0.30.10.8-0.2-0.4-0.70.60.90.80.81.2-0.6-1.6
One hour access (0.3 mA shock)1.11.33.00.20.51.1-1.11.11.1-1.10.8-0.50.5-0.5-1.01.11.01.2-1.2-0.31.01.31.0-1.5-1.4-1.7-1.7-0.91.71.6
Compulsive drug intake0.50.53.70.0-0.20.5-0.50.30.4-0.40.60.5-0.50.5-0.50.40.40.2-0.2-0.70.21.20.8-0.3-1.3-0.5-0.5-1.00.41.9
One hour access (shock baseline)0.70.81.30.51.00.9-0.91.10.9-0.90.6-1.11.1-1.1-0.81.00.81.1-1.10.90.80.50.4-0.9-0.3-0.9-0.90.61.1-0.6
Social response proportion2.22.46.4-1.9-2.1-1.81.8-1.5-1.41.4-1.81.6-1.61.61.5-1.5-1.5-1.51.4-2.5-1.3-1.0-1.60.71.40.10.1-2.5-0.11.2
Social responses0.50.73.9-0.4-0.9-0.60.6-0.4-0.60.5-0.6-0.20.2-0.20.6-0.7-0.6-0.70.6-1.8-0.5-1.1-0.7-0.30.1-1.2-1.2-2.00.81.2
Social time0.30.41.0-0.6-0.7-0.50.5-0.5-0.80.8-0.60.3-0.30.30.6-1.0-0.6-1.01.0-0.9-1.0-1.0-0.70.60.20.20.2-0.8-0.60.4
Soleus weight1.64.68.52.12.72.3-2.32.32.3-2.32.2-2.12.1-2.1-2.32.32.32.5-2.52.92.41.82.2-1.7-1.6-0.9-0.92.61.0-1.6
Bone: stiffness0.20.31.20.70.70.5-0.50.50.5-0.50.6-0.60.6-0.6-0.50.50.50.4-0.30.60.40.1-0.1-0.40.2-0.4-0.40.50.1-1.1
Tibialis anterior weight7.224.531.24.84.75.3-5.35.35.3-5.35.3-5.05.0-5.0-5.35.25.35.4-5.32.95.64.45.0-5.5-5.5-5.2-5.21.15.41.6
Time to tail flick, vehicle, before self-admin0.40.41.2-0.3-0.1-0.40.4-0.5-0.70.7-0.40.2-0.20.20.6-0.6-0.6-0.50.30.4-0.4-0.7-0.40.80.81.01.00.8-0.9-1.1
Time to tail flick, vehicle, after self-admin0.10.20.50.20.40.1-0.10.10.3-0.30.1-0.40.4-0.4-0.10.40.10.4-0.60.50.6-0.10.6-0.4-0.4-0.2-0.20.60.7-0.2
Time to tail flick, test, before self-admin0.60.62.30.60.60.4-0.40.40.3-0.40.4-1.31.3-1.3-0.30.30.30.5-0.60.20.6-0.50.2-1.2-0.6-1.3-1.3-0.11.50.1
Time to tail flick, test, after self-admin0.50.53.0-0.9-0.3-0.90.9-0.9-0.60.7-1.0-0.60.6-0.60.8-0.4-0.8-0.30.1-0.20.1-1.7-1.0-0.40.8-0.5-0.50.01.1-0.5
Delta time to tail flick, vehicle, before/after SA0.40.40.90.50.50.5-0.50.50.9-0.90.5-0.40.4-0.4-0.60.90.70.9-0.80.20.70.70.8-0.8-0.9-0.7-0.7-0.00.90.5
Delta time to tail flick, test, before/after SA1.51.42.8-1.3-1.0-1.51.5-1.5-1.11.2-1.50.9-0.90.91.4-1.0-1.4-1.11.0-0.4-0.8-1.5-1.31.11.71.21.20.1-0.8-0.7
Tibia length1.74.810.33.22.42.6-2.62.62.5-2.62.6-2.12.1-2.1-2.62.62.62.3-2.02.11.82.32.4-1.5-2.2-1.3-1.31.40.4-0.5
Ambulatory time before self-admin0.70.71.8-0.7-1.0-1.11.1-0.9-0.80.8-1.10.3-0.30.31.0-0.7-1.0-0.60.5-1.4-0.5-1.2-1.2-0.10.8-0.6-0.6-1.30.80.5
Ambulatory time after self-admin0.20.20.80.3-0.00.3-0.30.30.5-0.40.30.1-0.10.1-0.20.40.10.4-0.5-0.40.30.70.1-0.5-0.3-0.7-0.7-0.60.90.6
Bone: tissue strength0.90.91.4-1.2-1.0-1.01.0-1.0-1.01.0-1.11.2-1.21.21.0-1.0-1.0-1.11.0-0.9-1.1-0.8-0.80.90.80.70.7-0.7-0.80.4
Total heroin consumption0.40.53.2-0.10.40.1-0.10.2-0.30.00.10.1-0.10.1-0.1-0.5-0.0-0.40.61.0-0.6-0.1-0.31.00.61.21.21.2-1.8-1.2
Bone: trabecular number0.40.62.20.91.00.7-0.70.70.7-0.70.7-0.40.4-0.4-0.70.60.70.5-0.41.40.40.50.90.4-0.40.90.91.5-0.8-0.7
Bone: trabecular spacing0.81.14.40.40.10.6-0.60.60.6-0.60.5-0.80.8-0.8-0.60.60.60.7-0.7-0.90.50.40.3-1.5-1.2-2.1-2.1-1.52.01.6
Bone: trabecular thickness0.60.83.20.10.3-0.50.5-0.5-0.40.4-0.4-0.10.1-0.10.5-0.5-0.5-0.50.51.3-0.5-1.0-0.41.20.91.61.61.8-1.4-1.7
Bone: trabecular tissue density4.05.612.3-2.7-3.1-2.52.5-2.5-2.52.5-2.52.5-2.52.52.5-2.4-2.5-2.52.4-3.5-2.3-1.9-2.31.21.30.20.2-3.30.12.7
Water consumed over 24 hours2.12.53.61.61.91.6-1.61.61.6-1.61.5-1.81.8-1.8-1.61.61.61.5-1.91.91.91.11.8-1.6-1.5-1.0-1.01.61.5-0.5
Number of responses in last shaping day0.70.71.40.60.51.2-1.20.90.7-0.71.1-0.70.7-0.7-0.70.80.70.8-0.90.10.80.90.9-0.9-1.2-1.0-1.0-0.30.90.7