RGD1359108

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression RGD1359108 0.18 0.12 3.6e-11 0.08 0.07 0.07 0.08 2.3e-09 1.0e-08 2.0e-08 3.4e-09
2 pVTA mRNA stability RGD1359108 0.04 0.03 5.8e-03 0.03 0.01 0.02 0.02 1.2e-03 3.7e-02 1.5e-02 9.6e-03
3 Adipose alternative polyA XM_039109830.2 0.13 0.08 2.5e-10 0.07 0.07 0.07 0.07 2.6e-08 5.2e-08 1.8e-08 4.8e-08
4 Adipose alternative polyA XM_039109829.2 0.13 0.08 2.5e-10 0.07 0.07 0.07 0.07 2.7e-08 6.2e-08 1.8e-08 5.1e-08
5 Brain mRNA stability RGD1359108 0.07 0.04 9.8e-05 0.05 0.04 0.04 0.05 1.5e-05 5.1e-05 4.3e-05 2.3e-05
6 NAcc alternative TSS XM_039109829.2 0.04 0.02 4.6e-05 0.03 0.02 0.02 0.02 7.4e-05 1.4e-04 5.7e-04 1.4e-04
7 Brain alternative polyA XM_039109829.2 0.16 0.09 7.1e-11 0.12 0.1 0.11 0.12 1.4e-11 9.5e-10 2.8e-10 3.0e-11
8 Brain alternative polyA XM_039109830.2 0.17 0.09 1.8e-11 0.13 0.11 0.11 0.13 4.7e-12 2.8e-10 8.7e-11 8.8e-12
9 Brain isoform ratio XR_010066381.1 0.05 0.04 4.6e-03 0.03 0.02 0.02 0.03 8.6e-04 1.2e-02 7.5e-03 1.5e-03
10 Adipose isoform ratio XR_010066381.1 0.05 0.04 1.1e-03 0.02 0.01 0.02 0.01 5.5e-03 9.7e-03 3.6e-03 1.2e-02
11 RMTg gene expression RGD1359108 0.23 0.13 2.8e-04 0.13 0.09 0.1 0.15 2.3e-04 2.8e-03 1.4e-03 9.4e-05
12 NAcc mRNA stability RGD1359108 0.03 0.02 5.1e-04 0.02 0.02 0.02 0.02 7.5e-04 2.8e-04 6.0e-04 8.7e-04
13 IC isoform ratio NM_001007702.2 0.1 0.07 5.0e-03 0.06 0.03 0 0.04 1.7e-03 2.4e-02 2.4e-01 7.4e-03
14 NAcc alternative TSS NM_001007702.2 0.05 0.03 2.9e-06 0.03 0.03 0.04 0.03 1.4e-05 6.0e-06 3.4e-06 1.0e-05
15 NAcc alternative TSS XM_039109829.2 0.05 0.03 1.8e-06 0.03 0.04 0.04 0.03 1.3e-05 3.6e-06 2.7e-06 6.9e-06
16 NAcc alternative TSS NM_001007702.2 0.03 0.02 1.2e-04 0.02 0.02 0.02 0.02 8.1e-04 4.0e-04 1.4e-03 1.2e-03
17 Liver gene expression RGD1359108 0.04 0.03 8.4e-03 0.01 0.01 0 0.01 4.2e-02 4.1e-02 1.1e-01 3.7e-02
18 Liver alternative polyA XM_039109829.2 0.04 0.03 1.7e-03 0.01 0.01 0.01 0.01 7.2e-03 2.8e-02 2.1e-02 2.5e-02
19 Liver alternative polyA XM_039109830.2 0.04 0.03 1.2e-03 0.02 0.01 0.01 0.01 3.8e-03 2.6e-02 1.1e-02 2.1e-02
20 pVTA alternative TSS XM_039109829.2 0.03 0.02 6.0e-03 -0 0.02 0 0 7.5e-01 7.7e-03 1.4e-01 3.0e-01
21 pVTA alternative TSS NM_001007702.2 0.03 0.02 7.9e-03 -0 0.02 0 -0 8.8e-01 1.0e-02 1.7e-01 4.1e-01
22 pVTA alternative TSS XM_039109829.2 0.03 0.02 6.8e-03 -0 0.02 0.01 0 7.0e-01 1.3e-02 2.8e-02 1.7e-01
23 PL gene expression RGD1359108 0.31 0.09 1.7e-07 0.05 0.06 0.07 0.04 4.2e-06 1.5e-07 1.1e-07 1.6e-05
24 NAcc isoform ratio NM_001007702.2 0.06 0.03 2.7e-09 0.05 0.05 0.05 0.06 3.5e-08 3.3e-08 5.1e-08 4.4e-09
25 NAcc isoform ratio XM_039109829.2 0.04 0.03 9.2e-06 0.03 0.03 0.02 0.03 7.2e-05 1.0e-04 5.6e-04 2.0e-05
26 BLA gene expression RGD1359108 0.12 0.1 5.5e-04 0.07 0.06 0.06 0.06 8.2e-05 6.6e-04 3.6e-04 3.5e-04
27 IL gene expression RGD1359108 0.23 0.15 2.1e-03 0.03 0.02 -0.01 0.01 7.5e-02 1.2e-01 9.8e-01 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.61.02.31.2-1.21.1-1.1-1.11.1-1.21.21.21.1-0.91.5-0.8-0.60.60.80.6-0.70.7-1.51.5-1.5-1.00.2-0.1-0.1-0.7
Area under the delay curve0.10.22.10.5-0.50.3-0.4-0.30.4-0.30.30.3-0.00.00.0-0.1-0.10.10.40.00.3-0.30.1-0.10.1-1.4-0.10.2-0.2-0.5
BMI with tail2.910.115.23.4-3.43.5-3.5-3.43.4-3.43.43.43.8-3.62.0-3.0-3.83.83.73.1-3.33.3-1.41.4-1.2-1.73.8-3.83.91.2
BMI without tail1.68.311.83.1-3.13.2-3.2-3.13.1-3.13.13.13.4-3.33.0-2.8-2.92.92.82.8-3.13.1-2.72.7-2.6-1.62.7-2.62.4-0.6
Body weight6.729.137.86.1-6.16.1-6.1-6.06.1-6.16.16.16.1-6.05.0-5.5-5.75.75.75.2-5.35.3-4.24.2-4.1-4.45.2-5.04.5-0.5
Weight adjusted by age0.51.42.90.9-0.91.3-1.3-1.30.8-1.21.21.21.3-1.31.4-1.4-1.00.90.81.4-1.71.7-1.31.3-1.2-0.31.1-1.10.9-0.4
Bone surface1.53.07.31.8-1.81.8-1.8-1.71.8-1.81.81.81.8-1.72.7-1.7-1.11.01.11.5-1.51.5-2.72.7-2.7-1.20.6-0.4-0.1-1.7
Bone volume0.81.64.91.3-1.31.3-1.3-1.21.2-1.31.31.31.2-1.12.1-0.8-0.50.50.70.7-0.90.9-2.22.2-2.2-1.0-0.00.2-0.6-1.6
Breakpoint value in progressive ratio session0.10.20.5-0.00.0-0.40.40.70.00.7-0.7-0.70.20.10.50.50.2-0.1-0.4-0.6-0.30.3-0.70.7-0.70.4-0.50.4-0.4-0.3
Number of licking bursts0.10.20.5-0.50.5-0.50.50.5-0.50.5-0.5-0.5-0.30.4-0.20.20.4-0.5-0.5-0.10.2-0.20.1-0.10.10.7-0.30.4-0.4-0.1
Context. condit. distance diff. score0.60.71.5-0.80.8-0.90.90.9-0.90.9-0.9-0.9-0.91.0-1.20.90.6-0.6-0.6-0.80.7-0.71.2-1.21.20.5-0.40.3-0.00.8
Locomotion velocity, session 10.30.30.7-0.60.6-0.60.60.6-0.60.5-0.5-0.5-0.50.6-0.80.40.4-0.4-0.3-0.40.4-0.40.8-0.80.80.6-0.20.2-0.10.8
Locomotion distance, session 12.43.04.7-1.81.8-1.91.91.8-1.81.8-1.8-1.8-2.22.1-1.91.61.7-1.7-1.6-1.62.0-2.01.7-1.71.70.5-1.61.6-1.40.5
Locomotion velocity, session 20.30.41.30.6-0.60.5-0.5-0.50.6-0.50.50.50.2-0.2-0.2-0.6-0.70.70.80.70.2-0.20.4-0.40.4-1.10.8-0.80.90.9
Locomotion distance, session 23.85.39.5-2.32.3-2.42.42.3-2.32.3-2.3-2.3-2.62.6-3.12.32.0-2.0-1.7-2.32.4-2.43.1-3.03.00.9-1.81.6-1.31.6
Locomotion velocity, session 31.71.94.8-1.41.4-1.41.41.3-1.31.3-1.3-1.3-1.51.5-2.11.30.9-0.9-0.8-1.11.4-1.42.2-2.22.20.6-0.70.6-0.31.5
Locomotion distance, session 31.92.26.6-1.21.2-1.31.31.2-1.11.2-1.2-1.2-1.51.5-2.41.40.9-0.8-0.5-1.31.7-1.72.6-2.62.50.1-0.80.7-0.41.7
Stereotopy head waving bouts, day 30.70.81.80.7-0.70.9-0.9-0.90.7-0.90.90.90.8-0.91.3-0.9-0.60.60.40.8-1.11.1-1.41.4-1.4-0.20.6-0.50.4-1.3
Stereotopy head waving duration, day 31.51.82.51.2-1.21.5-1.4-1.51.2-1.51.51.51.4-1.51.2-1.5-1.41.41.21.3-1.61.6-1.11.1-1.0-0.61.6-1.61.5-0.1
Locomotion velocity, session 70.50.63.3-0.30.3-0.40.40.3-0.30.2-0.2-0.2-0.50.5-1.40.1-0.10.10.2-0.10.4-0.41.6-1.61.7-0.20.5-0.60.81.8
Locomotion distance, session 71.11.34.2-0.80.8-1.01.01.0-0.80.9-0.9-0.9-1.21.2-1.90.80.6-0.6-0.3-0.91.6-1.62.0-2.02.0-0.2-0.50.5-0.31.6
Stereotopy head waving bouts, day 70.80.92.80.8-0.80.9-0.9-0.90.8-0.90.90.90.8-0.8-0.2-0.6-1.21.21.20.8-0.70.70.5-0.50.6-0.61.4-1.51.71.3
Stereotopy head waving duration, day 72.22.75.51.7-1.71.8-1.8-1.81.7-1.71.71.71.8-1.70.7-1.5-2.02.11.91.6-1.61.6-0.30.3-0.2-1.12.1-2.22.31.1
Locomotion velocity, session 83.34.011.4-1.71.7-1.91.91.9-1.81.9-1.9-1.9-2.12.1-3.22.01.1-1.0-0.9-1.81.7-1.73.4-3.43.40.6-0.70.40.22.7
Locomotion distance, session 84.56.511.5-2.52.5-2.72.72.6-2.62.6-2.6-2.6-2.93.0-3.42.62.2-2.1-1.9-2.42.7-2.73.4-3.33.30.9-1.91.7-1.32.0
Degree of sensitization distance0.40.40.80.6-0.60.6-0.6-0.60.6-0.60.60.60.6-0.60.3-0.8-0.80.70.70.7-0.40.4-0.20.2-0.2-0.50.9-0.90.90.4
Degree of sensitization stereotypy1.31.44.90.9-0.90.9-0.9-1.00.9-0.90.90.90.9-0.9-0.7-0.6-1.41.51.50.8-0.70.71.1-1.21.2-0.71.7-1.92.22.2
Conditioned locomotion0.20.20.90.4-0.40.3-0.3-0.40.3-0.30.30.30.5-0.60.8-0.2-0.20.20.10.4-0.70.7-0.80.8-0.8-0.30.00.0-0.1-0.9
Cocaine response after cond. corrected0.30.50.80.7-0.70.7-0.7-0.70.8-0.80.80.80.8-0.90.8-0.4-0.80.80.70.7-0.90.9-0.70.7-0.7-0.20.5-0.60.6-0.5
Cocaine response after cond. not corrected0.30.40.60.7-0.70.7-0.7-0.70.7-0.80.80.80.6-0.70.8-0.5-0.60.70.60.8-0.40.4-0.70.7-0.7-0.60.5-0.40.4-0.6
Cocaine response before conditioning0.10.10.70.3-0.30.4-0.3-0.60.2-0.50.50.50.0-0.10.0-0.7-0.30.20.30.30.4-0.40.1-0.10.1-0.80.4-0.30.20.3
Saline control response0.81.12.41.1-1.11.1-1.1-1.11.1-1.11.11.11.0-1.01.5-0.9-0.70.70.70.8-0.70.7-1.51.5-1.6-1.00.4-0.30.1-1.2
Bone: connectivity density0.81.32.31.3-1.31.3-1.3-1.21.3-1.21.21.21.2-1.01.5-1.2-1.01.01.01.1-0.90.9-1.41.4-1.5-1.00.8-0.70.4-0.5
Bone: cortical apparent density0.10.20.7-0.40.4-0.40.40.3-0.40.4-0.4-0.4-0.20.00.20.10.4-0.4-0.6-0.1-0.50.5-0.30.4-0.30.8-0.20.2-0.3-0.7
Bone: cortical area4.06.58.92.8-2.82.8-2.8-2.82.7-2.82.82.83.0-2.92.7-2.5-2.52.52.52.5-3.03.0-2.42.4-2.3-1.52.2-2.11.8-0.7
Bone: cortical porosity0.60.64.90.4-0.40.3-0.3-0.30.3-0.30.30.30.2-0.11.2-0.10.3-0.3-0.20.3-0.00.0-1.41.4-1.5-0.7-0.60.8-1.0-2.2
Bone: cortical porosity1.01.12.91.0-1.01.0-1.0-1.01.0-1.01.01.00.9-0.91.6-0.7-0.60.60.61.0-0.80.8-1.61.6-1.6-1.00.3-0.1-0.1-1.7
Bone: cortical thickness1.32.23.21.6-1.61.7-1.6-1.71.5-1.61.61.61.7-1.71.4-1.7-1.51.51.51.6-1.81.8-1.21.2-1.2-0.91.4-1.41.2-0.4
Bone: cortical thickness0.50.61.80.6-0.60.6-0.6-0.70.6-0.70.70.70.6-0.7-0.2-0.9-0.90.90.90.9-0.50.50.5-0.50.5-0.51.2-1.31.31.3
Bone: cortical tissue density0.10.20.7-0.50.5-0.40.40.4-0.50.4-0.4-0.4-0.30.10.20.10.4-0.4-0.6-0.1-0.50.5-0.30.3-0.30.8-0.20.3-0.3-0.7
Condit. Reinf. active minus inactive responses2.12.43.9-1.61.6-1.71.61.5-1.61.6-1.6-1.6-1.81.7-2.01.21.4-1.4-1.3-1.41.8-1.81.9-1.91.90.9-1.11.0-0.91.2
Condit. Reinf. active-inactive response ratio0.60.61.0-0.90.9-0.90.90.8-0.90.8-0.8-0.8-1.00.9-0.90.40.8-0.8-0.7-0.61.0-1.00.8-0.80.80.6-0.60.6-0.60.6
Condit. Reinf. active responses1.41.73.6-1.41.4-1.41.41.3-1.41.3-1.3-1.3-1.41.4-1.91.01.0-1.0-0.9-1.11.4-1.41.9-1.91.90.8-0.70.6-0.41.2
Condit. Reinf. inactive responses0.81.02.3-1.01.0-1.11.11.1-1.11.1-1.1-1.1-1.01.0-1.51.10.8-0.7-0.7-1.10.8-0.81.5-1.51.50.8-0.50.4-0.20.7
Incentive salience index mean0.60.71.7-0.80.8-0.90.90.8-0.80.8-0.8-0.8-1.00.9-1.30.50.6-0.6-0.6-0.60.9-0.91.3-1.31.30.3-0.30.2-0.21.1
Condit. Reinf. lever presses0.20.31.30.3-0.30.2-0.2-0.20.3-0.10.10.10.2-0.2-0.4-0.6-0.60.60.50.6-0.40.40.5-0.50.5-0.50.9-0.91.01.1
Condit. Reinf. active minus inactive responses1.82.76.92.1-2.11.9-1.9-1.92.0-2.02.02.01.6-1.51.1-1.6-1.91.92.01.4-0.80.8-0.70.6-0.7-2.61.6-1.61.50.2
Condit. Reinf. active-inactive response ratio0.91.44.21.1-1.11.0-1.0-1.01.1-1.11.11.10.8-0.8-0.5-0.9-1.51.51.50.7-0.40.40.9-0.90.9-1.61.6-1.71.92.0
Condit. Reinf. active responses2.53.68.52.3-2.32.2-2.2-2.22.3-2.22.22.21.8-1.72.1-1.8-1.81.81.91.6-1.01.0-1.81.8-1.9-2.91.3-1.20.9-1.4
Condit. Reinf. inactive responses1.62.48.11.6-1.61.5-1.5-1.61.6-1.51.51.51.2-1.12.3-1.1-0.80.80.91.1-0.70.7-2.22.3-2.4-2.10.2-0.0-0.3-2.9
Condit. Reinf. lever presses1.92.84.01.9-1.91.9-1.9-2.01.8-2.02.02.01.7-1.61.5-1.8-1.81.81.81.7-1.41.4-1.21.2-1.2-1.81.7-1.61.5-0.3
Condit. Reinf. lever reinforcers received2.83.97.82.4-2.42.2-2.2-2.22.3-2.32.32.31.9-1.82.1-1.9-1.91.92.01.7-1.21.2-1.91.9-1.9-2.81.4-1.31.0-1.4
Conditioned reinforcement - actives0.10.61.00.8-0.80.8-0.8-0.90.8-0.80.80.80.9-0.70.4-0.9-0.90.90.90.8-0.70.7-0.20.2-0.2-0.21.0-1.01.00.5
Conditioned reinforcement - inactives0.30.92.31.0-1.01.1-1.0-1.21.0-1.21.21.20.6-0.60.7-1.3-0.90.90.91.1-0.40.4-0.50.5-0.5-1.51.0-0.90.70.3
Conditioned locomotion0.50.81.40.8-0.80.9-0.9-1.00.9-1.01.01.01.2-0.90.7-1.1-1.01.00.91.1-0.80.8-0.60.6-0.60.01.1-1.11.00.4
Patch foraging indifference point 0 sec0.10.20.60.6-0.60.4-0.4-0.30.6-0.30.30.30.3-0.30.7-0.3-0.20.20.40.00.1-0.1-0.70.7-0.7-0.7-0.20.3-0.5-0.4
Patch foraging indifference point AUC0.71.82.91.4-1.41.3-1.3-1.31.5-1.21.21.21.7-1.61.2-1.2-1.61.61.41.2-1.71.7-1.01.0-1.0-0.21.5-1.51.50.0
Delay disc. indifference point, 0s delay0.20.20.9-0.30.3-0.20.30.1-0.30.1-0.1-0.1-0.50.4-0.80.20.1-0.10.0-0.10.5-0.50.9-0.90.90.00.0-0.00.10.5
Delay disc. indifference point, 16s delay0.81.15.71.5-1.51.2-1.2-1.21.4-1.11.11.10.8-0.81.0-1.0-1.01.01.10.7-0.40.4-0.80.8-0.9-2.40.6-0.50.3-0.5
Delay disc. indifference point, 2s delay0.10.11.00.3-0.30.3-0.3-0.30.1-0.20.20.20.3-0.30.4-0.20.1-0.10.10.5-0.40.4-0.40.4-0.4-0.2-0.10.2-0.3-1.0
Delay disc. indifference point, 24s delay0.30.63.81.0-1.00.9-0.9-0.80.9-0.90.90.90.5-0.50.6-0.6-0.70.70.80.1-0.00.0-0.40.4-0.5-1.90.4-0.40.30.1
Delay disc. indifference point, 4s delay0.20.20.5-0.10.1-0.40.40.3-0.20.3-0.3-0.3-0.60.6-0.50.50.4-0.4-0.2-0.40.7-0.70.5-0.50.4-0.7-0.50.5-0.5-0.3
Delay disc. indifference point, 8s delay0.10.11.00.4-0.40.2-0.3-0.20.2-0.10.10.1-0.00.10.20.10.1-0.10.1-0.00.3-0.3-0.20.2-0.2-0.9-0.40.5-0.6-1.0
Indifference point function ln k0.10.40.8-0.60.6-0.60.60.6-0.70.6-0.6-0.6-0.70.7-0.90.30.5-0.5-0.5-0.30.6-0.60.9-0.90.80.3-0.20.2-0.20.6
Indifference point function log k0.10.40.8-0.60.6-0.60.60.6-0.70.6-0.6-0.6-0.70.7-0.90.30.5-0.5-0.5-0.30.6-0.60.9-0.90.80.3-0.20.2-0.20.6
Patch foraging total patch changes 0 sec0.10.20.90.6-0.60.4-0.5-0.40.6-0.40.40.40.3-0.20.5-0.4-0.30.30.50.10.2-0.2-0.40.4-0.5-0.90.10.0-0.1-0.1
Patch foraging total patch changes 12 sec1.01.32.71.3-1.41.2-1.2-1.01.5-1.11.11.11.2-1.20.4-0.9-1.61.61.60.8-0.90.9-0.10.1-0.0-1.11.4-1.51.60.9
Patch foraging total patch changes 18 sec0.10.20.40.5-0.50.5-0.5-0.40.5-0.40.40.40.5-0.50.6-0.3-0.30.30.40.1-0.10.1-0.60.6-0.6-0.20.1-0.0-0.1-0.3
Patch foraging total patch changes 24 sec0.20.71.50.8-0.80.9-0.8-0.71.0-0.70.70.70.9-0.91.2-1.0-0.60.60.60.8-0.80.8-1.21.2-1.2-0.30.4-0.30.0-1.0
Patch foraging total patch changes 6 sec0.20.41.00.9-0.90.5-0.6-0.41.0-0.50.50.50.6-0.50.9-0.5-0.60.60.60.4-0.10.1-0.90.9-0.9-0.80.2-0.1-0.0-0.5
Patch foraging time to switch 0 sec0.62.34.0-1.51.4-1.51.51.7-1.51.6-1.6-1.6-1.71.8-1.21.61.7-1.7-1.5-1.42.0-2.01.0-1.00.90.5-1.81.8-1.70.0
Patch foraging water rate 0 sec0.83.14.91.9-1.92.0-2.0-2.22.0-2.12.12.11.8-1.91.6-2.0-1.81.81.81.8-1.31.3-1.31.3-1.3-1.81.7-1.61.3-0.5
Patch foraging water rate 12 sec0.52.14.01.7-1.61.8-1.8-1.81.5-2.02.02.01.3-1.41.0-1.5-1.41.41.51.5-0.80.8-0.70.7-0.7-2.01.4-1.31.1-0.1
Patch foraging water rate 18 sec0.92.03.91.5-1.41.5-1.5-1.71.6-1.61.61.61.2-1.3-0.1-1.2-1.71.72.01.3-0.60.60.6-0.60.6-1.91.6-1.71.81.2
Patch foraging water rate 24 sec0.50.71.50.7-0.70.8-0.8-1.00.5-0.90.90.90.5-0.7-0.8-0.6-0.80.81.20.7-0.10.11.1-1.21.2-0.91.0-1.11.20.9
Patch foraging water rate 6 sec1.21.83.11.3-1.21.6-1.5-1.81.3-1.81.81.81.2-1.40.5-1.7-1.51.51.61.5-0.90.9-0.10.1-0.1-1.11.7-1.71.60.5
Seeking ratio, delayed vs. immediate footshock0.10.10.60.4-0.4-0.0-0.1-0.10.4-0.10.10.10.1-0.10.70.1-0.00.1-0.00.2-0.10.1-0.70.7-0.8-0.5-0.20.2-0.3-0.3
Distance traveled before self-admin0.10.32.0-0.60.6-0.40.50.3-0.60.5-0.5-0.5-0.40.2-0.80.40.3-0.3-0.4-0.50.2-0.20.7-0.70.81.4-0.10.00.10.6
Distance traveled after self-admin0.10.20.40.1-0.10.3-0.3-0.60.1-0.40.40.4-0.0-0.4-0.3-0.1-0.30.30.30.4-0.60.60.5-0.50.5-0.30.4-0.50.60.4
Extensor digitorum longus weight4.819.325.84.8-4.84.9-4.9-4.84.8-4.84.84.84.9-4.84.1-5.1-4.64.54.54.6-4.74.7-3.53.5-3.4-3.44.4-4.13.5-0.1
Bone: elastic displacement0.30.41.3-0.60.6-0.60.60.6-0.70.6-0.6-0.6-0.60.50.10.30.9-0.9-0.9-0.40.5-0.5-0.30.3-0.30.6-0.80.9-1.1-1.1
Bone: elastic work0.91.22.91.0-1.01.1-1.1-1.00.9-1.01.01.01.2-1.21.7-1.1-0.60.50.61.1-1.01.0-1.71.7-1.7-0.10.5-0.3-0.0-1.5
Bone: endosteal estimation3.48.211.33.2-3.23.2-3.2-3.13.1-3.13.13.13.4-3.22.8-2.8-3.03.02.92.8-3.13.1-2.52.5-2.4-1.92.7-2.62.4-0.3
Bone: endosteal perimeter1.53.66.11.9-1.92.0-2.0-1.91.9-1.91.91.92.4-2.22.2-1.6-1.81.81.71.8-2.52.5-2.12.1-2.0-0.51.6-1.51.4-0.8
Epididymis fat weight0.10.41.2-0.50.6-0.60.60.8-0.60.7-0.7-0.7-0.30.30.11.00.7-0.7-0.8-0.7-0.20.2-0.40.4-0.40.9-0.90.8-0.7-1.1
Delta time in closed arm before/after self-admin0.30.30.9-0.70.7-0.40.50.5-0.70.6-0.6-0.6-0.40.2-0.20.80.6-0.6-0.7-0.6-0.20.20.0-0.00.10.9-0.50.5-0.30.2
Delta time in open arm before/after self-admin0.30.42.40.8-0.80.3-0.4-0.41.0-0.40.40.40.1-0.0-0.2-0.5-0.80.90.90.30.1-0.10.4-0.40.3-1.50.6-0.60.60.5
Diff in mean of infusions in LGA sessions1.42.54.4-1.41.4-1.91.82.0-1.42.1-2.1-2.1-1.51.8-0.91.91.6-1.6-1.7-1.91.7-1.70.6-0.60.50.8-1.81.7-1.6-0.0
Delay discount exponential model param0.10.11.8-0.40.4-0.20.20.2-0.20.1-0.1-0.10.1-0.10.1-0.1-0.0-0.0-0.30.1-0.40.4-0.20.2-0.21.30.2-0.20.30.4
Extinction: sum of active levers before priming0.81.22.3-1.21.2-1.11.11.0-1.21.0-1.0-1.0-1.11.1-1.50.80.9-0.9-0.9-1.11.1-1.11.5-1.51.50.7-0.50.4-0.31.3
Active lever presses in extinction session 60.40.41.3-0.10.1-0.50.50.4-0.20.5-0.5-0.5-0.91.0-0.10.30.6-0.6-0.5-0.41.1-1.10.0-0.0-0.1-1.0-0.70.8-0.9-0.3
Bone: final force1.52.43.91.7-1.71.7-1.7-1.71.6-1.71.71.72.0-1.81.8-1.4-1.31.31.41.5-1.81.8-1.81.7-1.7-0.61.1-1.00.8-0.6
Bone: final moment2.33.85.62.2-2.22.2-2.2-2.12.1-2.12.12.12.4-2.22.3-1.7-1.71.71.81.8-2.22.2-2.22.1-2.1-1.01.4-1.31.0-0.9
Food consumed during 24 hour testing period1.52.94.11.8-1.81.8-1.8-1.81.8-1.81.81.81.7-1.71.7-2.0-1.81.71.62.0-1.81.8-1.51.5-1.5-1.71.7-1.61.4-0.2
Glucose0.10.10.20.3-0.30.4-0.4-0.40.4-0.40.40.40.3-0.40.3-0.2-0.30.40.30.2-0.10.1-0.20.2-0.2-0.20.3-0.30.30.1
Heart weight2.54.16.22.2-2.22.3-2.3-2.42.2-2.52.52.52.1-2.32.0-2.2-2.02.02.02.1-1.81.8-1.81.8-1.8-1.71.7-1.61.3-0.7
Delay discount hyperbolic model param0.10.11.3-0.40.4-0.30.30.3-0.20.2-0.2-0.20.0-0.0-0.00.00.0-0.0-0.2-0.0-0.20.2-0.00.00.01.10.2-0.20.30.5
Intermittent access intake day 1-15 change0.10.61.7-0.70.7-0.80.80.6-0.70.6-0.6-0.6-1.31.2-0.90.40.6-0.6-0.6-0.41.2-1.21.0-1.00.9-0.6-0.50.5-0.50.5
Intermittent access intake escalation0.10.61.6-0.60.6-0.70.70.5-0.60.5-0.5-0.5-1.31.2-0.80.40.6-0.7-0.6-0.31.2-1.20.9-0.80.7-0.7-0.60.6-0.70.2
Intermittent access intake escalation 20.30.61.8-0.50.5-0.70.60.5-0.50.5-0.5-0.5-1.11.1-1.20.20.3-0.3-0.2-0.21.1-1.11.3-1.31.3-0.7-0.10.1-0.11.0
Intermitt. access day 1 inactive lever presses0.00.31.3-0.50.5-0.30.30.4-0.50.3-0.3-0.3-0.10.1-0.90.50.1-0.1-0.2-0.5-0.40.40.9-0.90.91.10.1-0.30.51.1
Intermitt. access day 15 inactive lever presses0.10.62.70.8-0.80.8-0.8-0.90.8-1.11.11.10.3-0.41.0-0.6-0.40.40.50.6-0.20.2-0.90.9-1.0-1.70.10.1-0.3-1.0
Intermitt. access escalation Index0.10.41.4-0.50.5-0.60.60.8-0.50.7-0.7-0.7-0.50.40.10.70.8-0.7-0.7-0.70.1-0.1-0.40.4-0.40.4-1.01.0-1.1-1.2
Intermittent access day 1 total infusions0.82.54.31.9-1.91.7-1.8-1.91.9-1.81.81.81.6-1.71.4-1.9-1.71.71.71.5-1.01.0-1.21.1-1.2-2.11.5-1.41.20.0
Intermittent access day 15 total infusions0.51.14.11.2-1.21.1-1.1-1.31.2-1.31.31.30.7-0.80.6-1.3-1.21.21.21.2-0.40.4-0.30.3-0.4-2.01.2-1.11.00.6
Intermittent access terminal intake (last 3 days)0.61.05.61.2-1.21.0-1.0-1.21.1-1.11.11.10.4-0.50.5-1.5-1.11.01.11.30.1-0.1-0.20.2-0.3-2.41.1-1.00.80.6
Intermittent access total infusions2.73.28.02.2-2.21.9-1.9-2.12.1-2.02.02.01.5-1.61.3-2.1-2.02.02.02.0-1.01.0-0.90.9-0.9-2.81.9-1.81.60.8
Intermittent access day 1 locomotion0.40.72.30.8-0.80.8-0.8-0.90.8-0.80.80.80.8-0.91.4-1.0-0.50.50.40.8-0.30.3-1.51.5-1.5-0.50.4-0.3-0.0-0.9
Intermittent access day 15 total locomotion0.20.81.80.8-0.80.9-0.9-1.10.9-1.01.01.00.7-0.91.3-1.3-0.70.60.51.2-0.40.4-1.21.2-1.3-0.90.6-0.40.1-1.0
Intermittent access total locomotion0.60.82.00.9-0.90.8-0.8-1.00.9-0.80.80.80.7-0.81.4-1.2-0.70.60.51.0-0.30.3-1.41.4-1.4-0.80.5-0.40.1-0.6
Intermittent access standard deviation0.21.06.11.2-1.20.9-0.9-1.11.2-1.01.01.00.2-0.2-0.1-1.2-1.11.11.30.80.5-0.50.5-0.50.4-2.51.0-0.90.81.1
Left kidney weight1.411.015.03.7-3.73.8-3.8-3.73.7-3.73.73.73.8-3.92.9-3.3-3.63.63.53.2-3.43.4-2.42.4-2.3-2.43.3-3.23.00.3
Right kidney weight2.014.318.94.3-4.34.3-4.3-4.34.3-4.34.34.33.8-4.13.6-3.9-3.93.93.83.8-3.23.2-3.13.0-3.1-3.93.6-3.43.0-0.6
Cocaine induced anxiety0.71.84.8-1.51.5-1.41.41.6-1.51.6-1.6-1.6-1.11.1-1.71.51.0-0.9-1.1-1.60.6-0.61.5-1.51.62.2-0.60.4-0.01.6
Post-drug Anxiety0.20.31.4-0.60.6-0.40.40.5-0.60.5-0.5-0.5-0.20.2-0.70.40.2-0.2-0.3-0.4-0.30.30.6-0.70.71.20.0-0.10.30.7
Baseline Anxiety0.20.31.20.5-0.50.5-0.5-0.60.5-0.60.60.60.3-0.30.7-0.5-0.20.20.40.7-0.50.5-0.60.6-0.7-0.80.10.0-0.2-1.1
Tail length1.57.917.62.9-2.82.9-2.9-2.82.9-2.92.92.92.7-2.74.2-2.7-1.91.91.92.5-2.52.5-4.14.1-4.2-2.41.3-0.90.3-2.9
Length with tail3.515.623.24.4-4.44.4-4.4-4.24.4-4.44.44.44.1-4.24.8-4.1-3.53.53.53.7-3.73.7-4.54.4-4.5-3.62.8-2.41.7-2.2
Length without tail1.36.710.23.2-3.23.1-3.1-2.93.2-3.03.03.02.7-2.72.1-2.7-2.82.83.02.4-2.22.2-1.61.5-1.5-3.02.3-2.21.9-0.1
Times rat made contact with spout0.30.31.00.5-0.50.4-0.4-0.40.4-0.40.40.40.2-0.40.9-0.6-0.20.10.10.5-0.30.3-1.01.0-1.0-0.80.10.0-0.2-0.9
Lifetime Intake2.63.27.22.1-2.11.9-1.9-2.02.1-2.02.02.01.6-1.61.2-2.1-2.12.12.01.9-1.11.1-0.80.8-0.8-2.72.0-1.91.70.9
Liver weight, left1.83.18.21.7-1.71.7-1.7-1.61.6-1.61.61.61.9-1.92.8-1.5-1.11.10.91.4-2.02.0-2.92.9-2.9-0.80.7-0.50.2-1.8
Liver weight, right1.52.64.41.8-1.81.7-1.7-1.81.7-1.81.81.81.7-1.72.1-1.4-1.31.31.31.6-1.61.6-2.02.0-2.0-1.51.1-1.00.8-1.1
Locomotor activity1.11.72.8-1.51.5-1.41.41.3-1.31.2-1.2-1.2-1.41.3-1.11.71.4-1.4-1.2-1.61.5-1.51.0-0.90.91.2-1.51.5-1.3-0.3
Locomotor testing distance0.51.22.2-1.31.2-1.11.11.0-1.10.9-0.9-0.9-1.01.0-0.71.51.2-1.2-1.0-1.41.1-1.10.5-0.50.51.4-1.41.3-1.2-0.8
Locomotor testing rearing0.41.63.1-1.41.3-1.31.31.2-1.21.2-1.2-1.2-1.31.4-1.21.71.2-1.2-1.0-1.61.2-1.21.1-1.11.11.3-1.41.3-1.1-0.0
Locomotion in novel chamber0.10.21.7-0.50.5-0.30.30.5-0.50.4-0.4-0.40.10.0-0.10.30.3-0.3-0.4-0.2-0.40.4-0.10.10.01.3-0.10.1-0.0-0.1
Locomotion in novel chamber post-restriction0.41.22.0-1.21.2-1.11.11.2-1.31.3-1.3-1.3-1.11.1-0.61.11.4-1.4-1.3-1.00.9-0.90.3-0.30.31.0-1.21.2-1.2-0.7
Fecal boli incidents, locomotor time 10.10.21.4-0.0-0.20.1-0.10.0-0.10.0-0.0-0.00.2-0.10.6-0.10.3-0.3-0.30.1-0.60.6-0.80.8-0.80.5-0.30.4-0.5-1.2
Change in fecal boli incidents, locomotor task0.10.10.50.10.20.2-0.1-0.10.3-0.10.10.1-0.10.20.60.20.1-0.1-0.2-0.30.4-0.4-0.70.7-0.7-0.6-0.40.5-0.5-0.5
Time >=10cm from walls, locomotor time 11.11.45.11.3-1.31.3-1.3-1.61.1-1.51.51.50.7-0.90.9-1.7-1.00.91.11.6-0.40.4-0.70.7-0.7-2.31.0-0.80.5-0.5
Bouts of movement, locomotor time 10.20.30.6-0.50.5-0.80.70.7-0.70.7-0.7-0.7-0.50.5-0.50.50.5-0.5-0.6-0.80.5-0.50.4-0.40.40.4-0.40.3-0.30.5
Total resting periods, locomotor time 10.10.10.3-0.20.2-0.50.40.4-0.40.4-0.4-0.4-0.20.30.20.20.4-0.4-0.5-0.50.2-0.2-0.40.4-0.40.2-0.40.4-0.5-0.2
Rest time, locomotor task time 10.10.10.2-0.20.1-0.30.30.3-0.30.3-0.3-0.3-0.20.30.30.20.3-0.3-0.4-0.4-0.00.0-0.40.4-0.4-0.2-0.20.2-0.20.2
Distance moved, locomotor task time 10.10.43.4-0.70.7-0.30.40.4-0.50.5-0.5-0.5-0.1-0.1-0.90.50.1-0.1-0.1-0.4-0.20.20.8-0.91.01.80.1-0.20.40.6
Vertical activity count, locomotor time 10.10.52.1-0.70.8-0.60.60.7-0.40.7-0.7-0.7-0.30.3-1.10.70.3-0.3-0.2-0.70.2-0.21.1-1.11.21.4-0.30.2-0.00.2
Time >=10cm from walls, locomotor time 21.03.04.71.8-1.82.0-2.0-2.01.7-2.02.02.01.6-1.71.9-2.2-1.41.41.62.1-1.41.4-1.61.6-1.6-2.11.4-1.20.8-1.4
Bouts of movement, locomotor time 20.00.11.30.6-0.50.2-0.3-0.40.2-0.30.30.30.2-0.20.3-0.2-0.20.20.20.1-0.10.1-0.20.2-0.3-1.10.2-0.20.10.1
Total resting periods, locomotor time 20.00.00.70.4-0.3-0.1-0.0-0.10.0-0.10.10.10.1-0.10.20.00.0-0.00.0-0.1-0.00.0-0.20.2-0.2-0.8-0.10.1-0.1-0.1
Rest time, locomotor task time 20.50.81.4-0.80.8-1.21.11.1-0.91.1-1.1-1.1-0.91.0-0.51.21.0-0.9-1.1-1.11.0-1.00.3-0.30.30.3-1.11.0-0.90.1
Distance moved, locomotor task time 20.50.73.0-0.70.8-0.30.40.4-0.50.5-0.5-0.5-0.30.3-1.50.3-0.00.10.1-0.3-0.10.11.6-1.61.71.30.4-0.60.81.5
Vertical activity count, locomotor time 20.20.41.00.3-0.20.5-0.5-0.50.5-0.40.40.40.5-0.4-0.6-0.4-0.80.80.90.4-0.60.60.8-0.80.90.40.8-0.91.00.7
Light reinforcement 10.62.66.31.6-1.61.6-1.6-1.31.5-1.41.41.41.9-1.80.3-1.6-2.02.12.01.6-1.71.70.0-0.00.2-0.42.3-2.42.51.7
Light reinforcement 21.32.84.61.8-1.81.7-1.7-1.51.8-1.61.61.62.0-1.90.9-1.9-2.12.12.01.9-1.81.8-0.50.5-0.4-0.82.2-2.12.11.3
Bone: marrow area3.38.011.23.1-3.13.1-3.1-3.13.1-3.13.13.13.4-3.22.8-2.8-2.92.92.82.8-3.13.1-2.52.5-2.4-1.82.6-2.62.3-0.3
Bone: maximum diameter3.77.411.02.9-2.92.9-2.9-2.92.8-2.92.92.93.1-3.03.2-2.7-2.52.52.32.5-3.33.3-3.13.0-3.0-1.62.1-2.01.6-1.4
Bone: maximum force2.75.27.72.6-2.62.6-2.6-2.52.5-2.52.52.52.8-2.72.3-2.0-2.32.32.32.1-2.72.7-2.02.0-1.9-1.32.0-1.91.8-0.5
Bone: maximum moment3.56.69.32.9-2.92.9-2.9-2.92.8-2.92.92.93.0-2.92.7-2.3-2.52.52.62.3-2.92.9-2.42.4-2.3-1.72.1-2.01.8-0.9
Mean time between licks in bursts0.10.51.10.6-0.60.6-0.6-0.50.5-0.60.60.60.8-0.60.4-1.0-0.80.80.60.9-0.80.8-0.30.3-0.20.11.0-1.01.00.6
Mean num. licks in bursts0.20.61.90.9-0.90.8-0.9-0.90.8-0.90.90.90.6-0.70.8-0.8-0.60.60.70.6-0.50.5-0.70.7-0.8-1.40.5-0.40.2-0.5
Cd content in liver2.32.53.61.7-1.71.7-1.7-1.71.7-1.71.71.71.9-1.51.6-1.8-1.71.71.61.9-1.71.7-1.41.4-1.3-0.71.7-1.61.5-0.3
Co content in liver0.10.20.50.4-0.40.4-0.4-0.40.4-0.40.40.40.3-0.40.7-0.2-0.20.20.20.1-0.30.3-0.70.7-0.7-0.4-0.00.0-0.1-0.5
Cu content in liver0.10.10.6-0.50.5-0.40.40.4-0.50.4-0.4-0.4-0.30.3-0.00.50.4-0.4-0.6-0.20.1-0.1-0.10.1-0.10.8-0.30.3-0.2-0.2
Fe content in liver0.50.74.5-0.30.3-0.30.30.3-0.40.3-0.3-0.3-0.20.21.00.30.8-0.8-0.9-0.30.0-0.0-1.31.3-1.40.5-1.01.1-1.3-2.1
K content in liver0.90.91.8-0.90.9-0.90.90.8-0.80.8-0.8-0.8-1.11.0-0.61.31.1-1.1-0.9-1.11.3-1.30.4-0.40.40.5-1.31.3-1.2-0.8
Mg content in liver0.20.20.9-0.30.3-0.20.30.2-0.30.2-0.2-0.2-0.40.3-0.00.90.5-0.4-0.4-0.60.5-0.5-0.10.1-0.10.2-0.80.7-0.6-0.7
Mn content in liver0.10.20.60.3-0.30.3-0.3-0.40.4-0.40.40.40.4-0.30.6-0.2-0.30.30.20.5-0.30.3-0.60.6-0.6-0.10.1-0.10.1-0.8
Na content in liver2.42.74.2-1.81.8-1.71.71.7-1.71.7-1.7-1.7-1.71.8-1.02.11.9-1.9-1.8-2.01.7-1.70.7-0.70.71.4-2.02.0-1.9-0.7
Rb content in liver1.21.33.8-0.90.9-1.01.01.0-1.21.0-1.0-1.0-1.01.2-0.72.01.4-1.3-1.1-1.81.4-1.40.4-0.40.40.6-1.61.5-1.3-1.0
Se content in liver2.42.94.1-2.02.0-1.91.91.8-1.81.8-1.8-1.8-1.91.7-1.11.82.0-2.0-2.0-1.61.4-1.40.7-0.70.71.8-2.02.0-2.0-0.6
Sr content in liver2.62.33.0-1.71.7-1.71.71.7-1.71.7-1.7-1.7-1.51.7-1.71.31.5-1.5-1.4-1.21.3-1.31.5-1.51.51.6-1.21.2-1.00.9
Zn content in liver0.10.10.40.1-0.10.2-0.1-0.20.3-0.20.20.20.2-0.2-0.10.0-0.30.30.30.3-0.30.30.2-0.20.20.40.3-0.30.40.6
Bone: minimum diameter1.73.24.62.0-2.02.0-2.0-2.01.9-2.02.02.02.2-2.01.6-1.6-1.81.91.91.6-2.02.0-1.41.4-1.3-1.21.6-1.61.5-0.4
Time in familiar zone, hab. session 10.91.01.61.0-1.01.1-1.1-1.11.0-1.01.01.01.2-1.11.0-1.0-1.01.00.91.0-1.31.3-0.90.9-0.9-0.41.0-0.90.8-0.5
Time in novel zone, hab. session 13.33.76.6-1.81.8-1.91.91.9-1.81.9-1.9-1.9-2.12.1-2.62.11.5-1.4-1.3-2.02.3-2.32.6-2.62.50.9-1.41.2-0.81.8
Total zone transitions, hab. session 16.49.013.6-3.23.2-3.23.23.1-3.23.1-3.1-3.1-3.63.3-1.93.03.6-3.6-3.4-3.03.3-3.31.4-1.41.21.2-3.63.7-3.7-0.8
Total locomotion distance, hab. session 14.46.313.5-2.62.6-2.62.62.5-2.62.5-2.5-2.5-3.02.7-0.82.23.2-3.2-3.1-2.32.5-2.50.3-0.30.11.0-3.33.5-3.7-1.5
Locomotion velocity, hab. session 12.84.010.9-1.91.9-2.02.01.9-2.01.9-1.9-1.9-2.42.1-0.11.52.6-2.7-2.6-1.62.0-2.0-0.30.4-0.60.3-2.83.0-3.3-1.9
Time in familiar zone, hab. session 20.30.31.20.6-0.60.5-0.5-0.60.6-0.50.50.50.3-0.4-0.1-0.6-0.70.70.70.5-0.20.20.3-0.30.3-1.10.8-0.80.80.5
Time in novel zone, hab. session 20.50.52.1-0.70.7-0.70.70.8-0.80.8-0.8-0.8-0.40.6-0.50.90.8-0.8-0.7-0.90.4-0.40.3-0.30.31.5-0.80.8-0.70.0
Total zone transitions, hab. session 24.05.16.7-2.52.5-2.52.52.5-2.62.5-2.5-2.5-2.62.5-2.42.32.3-2.3-2.3-2.32.1-2.12.2-2.12.11.6-2.01.9-1.60.9
Total locomotion distance, hab. session 21.31.73.0-1.51.5-1.51.51.4-1.51.4-1.4-1.4-1.51.4-0.51.01.7-1.7-1.7-1.11.1-1.10.2-0.20.10.9-1.51.6-1.7-0.6
Locomotion velocity, hab. session 20.91.22.7-1.21.2-1.21.21.1-1.31.1-1.1-1.1-1.31.1-0.10.81.5-1.5-1.6-0.80.9-0.9-0.20.2-0.20.7-1.41.5-1.6-0.7
Novel to familiar place preference ratio0.60.72.6-0.40.4-0.30.30.3-0.40.3-0.3-0.3-0.20.21.10.10.9-1.0-1.0-0.10.1-0.1-1.51.5-1.50.8-1.01.2-1.5-1.6
Novelty place preference0.91.13.8-0.80.8-0.70.70.7-0.80.7-0.7-0.7-0.60.60.80.51.3-1.4-1.3-0.40.6-0.6-1.21.3-1.31.1-1.51.7-2.0-1.7
Time in novel zone, NPP test1.01.24.2-0.90.9-0.90.90.8-0.90.8-0.8-0.8-0.70.70.70.61.4-1.5-1.4-0.60.7-0.7-1.11.1-1.11.2-1.61.8-2.1-1.6
Total zone transitions, NPP test2.94.46.2-2.32.3-2.32.32.3-2.32.3-2.3-2.3-2.32.3-2.52.31.9-1.9-1.9-2.21.8-1.82.3-2.32.31.5-1.71.5-1.11.5
Total locomotion distance, NPP test1.01.52.2-1.51.5-1.41.41.4-1.51.4-1.4-1.4-1.31.2-1.21.11.3-1.3-1.3-1.10.7-0.71.0-1.01.01.3-1.01.0-0.90.7
Locomotion velocity, NPP test0.60.91.5-1.21.2-1.11.11.1-1.21.1-1.1-1.1-1.00.9-0.90.81.0-1.0-1.1-0.80.4-0.40.7-0.70.71.1-0.80.7-0.70.6
Intraocular pressure0.40.71.90.7-0.70.8-0.8-0.50.8-0.50.50.51.2-0.91.3-0.5-0.70.70.50.6-1.11.1-1.41.4-1.30.20.6-0.60.5-0.8
Delta distance traveled before/after self-admin0.50.62.90.7-0.70.8-0.8-1.00.7-0.90.90.90.4-0.60.7-0.6-0.70.70.71.0-0.60.6-0.50.5-0.5-1.70.5-0.50.50.1
Delta ambulatory time before/after self-admin0.10.21.70.4-0.40.5-0.5-0.60.5-0.60.60.60.1-0.30.5-0.3-0.40.40.40.6-0.40.4-0.40.4-0.4-1.30.2-0.20.2-0.1
Parametrial fat weight0.30.83.0-0.30.3-0.60.50.6-0.30.5-0.5-0.5-0.70.9-1.40.60.3-0.30.0-0.61.3-1.31.5-1.51.5-0.6-0.50.4-0.31.7
Pavlov. Cond. lever latency0.30.40.9-0.60.6-0.60.60.6-0.60.6-0.6-0.6-0.70.7-0.80.90.5-0.5-0.4-1.00.8-0.80.8-0.80.80.3-0.60.5-0.30.1
Pavlov. Cond. magazine entry latency0.50.61.9-0.40.4-0.50.50.5-0.40.6-0.6-0.6-0.10.20.80.40.8-0.9-0.9-0.1-0.30.3-1.11.1-1.11.0-1.01.2-1.4-1.4
Pavlov. Cond. change in total contacts0.40.40.9-0.80.8-0.70.70.7-0.70.7-0.7-0.7-0.50.5-0.30.60.8-0.8-0.8-0.60.5-0.50.1-0.10.10.9-0.80.8-0.8-0.3
Pavlov. Cond. index score0.20.20.8-0.20.2-0.20.20.2-0.20.2-0.2-0.20.1-0.10.7-0.10.4-0.5-0.50.2-0.30.3-0.90.9-0.90.6-0.50.6-0.8-0.9
Pavlov. Cond. latency score0.20.31.2-0.00.00.0-0.00.00.00.0-0.0-0.00.3-0.30.9-0.20.3-0.3-0.30.4-0.50.5-1.11.1-1.10.6-0.30.5-0.7-0.9
Pavlov. Cond. lever contacts0.20.31.00.3-0.30.4-0.4-0.40.3-0.40.40.40.6-0.60.9-0.6-0.20.20.10.7-0.70.7-1.01.0-1.00.00.2-0.1-0.1-0.5
Pavlov. Cond. magazine entry number0.40.51.70.5-0.50.4-0.4-0.50.4-0.50.50.5-0.0-0.1-0.7-0.3-0.70.80.80.10.4-0.41.0-1.01.0-1.30.9-1.01.11.0
Pavlov. Cond. intertrial magazine entries0.60.72.3-0.40.4-0.50.50.4-0.50.4-0.4-0.4-1.01.0-1.30.40.3-0.3-0.1-0.71.4-1.41.5-1.51.4-1.0-0.20.2-0.10.6
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.20.2-0.20.20.2-0.20.3-0.3-0.30.1-0.00.5-0.00.4-0.5-0.50.2-0.30.3-0.70.7-0.70.6-0.50.6-0.8-0.8
Pavlov. Cond. response bias0.20.30.8-0.20.2-0.20.20.2-0.20.2-0.2-0.20.1-0.10.7-0.10.4-0.5-0.50.2-0.40.4-0.90.9-0.90.8-0.50.6-0.8-0.9
Pavlov. Cond. lever latency0.70.91.9-0.90.9-0.90.90.9-0.91.0-1.0-1.0-0.90.9-0.61.41.1-1.1-1.0-1.31.0-1.00.4-0.40.40.8-1.41.4-1.3-0.4
Pavlov. Cond. magazine entry latency0.30.40.7-0.70.7-0.80.80.7-0.70.7-0.7-0.7-0.80.8-0.60.50.6-0.6-0.7-0.60.8-0.80.6-0.60.50.2-0.40.4-0.30.4
Pavlov. Cond. change in total contacts0.20.61.50.7-0.70.7-0.7-0.60.6-0.70.70.70.6-0.60.3-0.8-0.90.90.80.8-0.70.7-0.10.1-0.1-0.71.1-1.21.20.9
Pavlov. Cond. index score0.10.20.60.3-0.30.2-0.3-0.20.2-0.30.30.30.2-0.20.1-0.7-0.50.50.30.6-0.20.20.0-0.00.0-0.50.8-0.80.70.6
Pavlov. Cond. latency score0.40.61.40.8-0.80.7-0.7-0.70.7-0.80.80.80.7-0.70.7-1.2-0.90.90.71.1-0.70.7-0.50.5-0.5-0.71.1-1.11.00.3
Pavlov. Cond. lever contacts0.50.81.50.9-0.90.9-0.9-0.80.8-0.90.90.90.8-0.80.6-1.2-1.01.00.91.1-0.80.8-0.40.4-0.4-0.91.2-1.21.10.3
Pavlov. Cond. magazine entry number0.10.10.70.2-0.20.3-0.3-0.30.2-0.20.20.20.3-0.40.50.00.1-0.10.10.0-0.30.3-0.60.6-0.60.3-0.30.4-0.5-0.8
Pavlov. Cond. intertrial magazine entries0.20.52.50.8-0.80.6-0.6-0.70.8-0.70.70.70.4-0.41.0-0.1-0.20.30.40.1-0.10.1-1.01.0-1.1-1.2-0.30.3-0.5-1.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.4-0.40.3-0.3-0.30.3-0.40.40.40.2-0.20.1-0.7-0.50.50.40.6-0.20.20.0-0.00.0-0.60.8-0.80.80.6
Pavlov. Cond. response bias0.10.10.60.1-0.10.1-0.1-0.10.1-0.20.20.20.00.0-0.3-0.4-0.40.40.30.3-0.10.10.4-0.40.4-0.40.7-0.70.80.8
Time in closed arm before self-admin0.40.72.60.5-0.50.7-0.7-0.60.4-0.60.60.61.2-1.2-0.1-0.4-0.80.90.90.7-1.61.60.2-0.20.31.01.1-1.21.40.4
Time in closed arm after self-admin0.30.33.4-0.60.6-0.20.20.3-0.70.4-0.4-0.40.3-0.4-0.20.80.4-0.3-0.4-0.4-1.11.10.0-0.00.21.8-0.10.00.30.1
Time in open arm before self-admin0.40.52.3-0.30.30.1-0.0-0.1-0.3-0.20.20.2-0.1-0.01.2-0.20.5-0.6-0.70.30.0-0.0-1.41.5-1.50.3-0.50.7-0.9-1.0
Time in open arm after self-admin0.40.43.50.8-0.80.3-0.4-0.51.0-0.60.60.6-0.00.00.5-0.7-0.60.60.60.50.4-0.4-0.40.4-0.5-1.90.3-0.2-0.0-0.1
Bone: periosteal estimation4.811.416.13.7-3.73.7-3.7-3.63.6-3.73.73.74.0-3.83.4-3.4-3.43.43.33.3-3.93.9-3.03.0-2.9-2.03.1-3.02.6-0.6
Bone: periosteal perimeter4.59.012.63.2-3.23.3-3.3-3.23.1-3.23.23.23.5-3.43.4-2.8-2.82.82.72.8-3.53.5-3.23.1-3.1-1.62.5-2.42.0-1.4
Bone: post-yield work1.22.03.01.7-1.71.6-1.6-1.71.7-1.71.71.71.5-1.51.4-0.7-1.41.51.40.8-1.51.5-1.21.2-1.2-1.70.9-1.01.0-1.0
Progressive ratio test 1 active lever presses1.32.26.92.0-2.01.5-1.6-1.61.9-1.51.51.51.2-1.11.4-1.8-1.61.61.61.6-0.60.6-1.11.1-1.2-2.61.3-1.20.90.1
Progressive ratio test 1 breakpoint1.22.16.41.9-1.91.5-1.5-1.61.8-1.51.51.51.2-1.11.3-1.7-1.61.61.61.5-0.60.6-1.01.0-1.1-2.51.4-1.21.00.2
Progressive ratio test 1 inactive lever presses0.00.11.00.2-0.2-0.00.0-0.10.3-0.10.10.1-0.30.30.1-0.10.0-0.00.0-0.00.4-0.4-0.00.0-0.1-1.0-0.20.3-0.4-0.4
Progressive ratio test 2 active lever presses0.50.71.61.2-1.20.9-0.9-0.91.1-0.80.80.80.8-0.70.5-1.0-1.11.11.10.8-0.30.3-0.30.3-0.3-1.31.0-1.00.90.4
Progressive ratio test 2 breakpoint0.60.81.71.2-1.20.9-1.0-0.91.1-0.90.90.90.8-0.70.5-1.0-1.11.11.10.9-0.30.3-0.30.3-0.3-1.31.0-1.00.90.4
Progressive ratio test 2 inactive lever presses0.10.20.80.5-0.50.5-0.5-0.50.5-0.60.60.60.1-0.20.7-0.6-0.20.20.20.40.1-0.1-0.60.6-0.7-0.90.1-0.0-0.2-0.5
Incentive Sensitization - Responses0.00.10.4-0.30.3-0.30.30.4-0.20.4-0.4-0.4-0.20.2-0.40.30.1-0.1-0.1-0.30.6-0.60.3-0.30.40.6-0.10.1-0.00.2
Incentive Sensitization - Breakpoint0.00.00.20.0-0.0-0.10.00.20.10.2-0.2-0.2-0.00.0-0.20.1-0.10.20.1-0.10.5-0.50.2-0.20.20.30.1-0.10.20.1
Sum of active levers in priming session hrs 5-60.10.10.90.5-0.50.2-0.2-0.30.4-0.20.20.20.2-0.10.0-0.2-0.20.20.30.20.4-0.40.1-0.10.0-0.90.1-0.10.0-0.1
Progressive ratio0.10.42.6-0.90.9-0.50.60.7-0.80.7-0.7-0.7-0.30.2-0.20.80.7-0.7-0.8-0.50.0-0.00.0-0.00.11.6-0.60.5-0.4-0.3
Food seeking constrained by brief footshock14.918.626.55.1-5.14.8-4.9-5.05.1-4.94.94.94.3-4.33.5-4.8-4.84.84.84.6-3.33.3-2.62.6-2.6-5.04.4-4.23.70.1
Seeking ratio, punishment vs. effort3.27.016.23.3-3.32.9-3.0-3.13.2-3.03.03.02.3-2.31.7-3.1-3.13.13.12.8-1.51.5-1.01.0-1.1-4.02.8-2.62.30.5
Retroperitoneal fat weight0.73.26.7-1.61.6-1.81.71.7-1.71.7-1.7-1.7-1.81.8-2.61.91.5-1.4-1.1-1.92.1-2.12.6-2.62.60.7-1.31.2-0.91.8
Reaction time number correct0.10.31.40.2-0.10.6-0.5-0.60.1-0.40.40.40.9-0.90.5-0.5-0.0-0.00.20.4-0.70.7-0.60.6-0.51.20.10.0-0.2-0.9
Reaction time mean minus median0.10.91.9-0.90.9-1.00.90.9-0.80.8-0.8-0.8-1.41.3-1.10.90.7-0.7-0.8-1.01.2-1.21.1-1.11.0-0.2-0.60.6-0.40.4
Reaction time mean minus median AUC0.10.61.2-0.70.7-0.80.70.7-0.70.7-0.7-0.7-1.11.0-1.00.70.4-0.4-0.6-0.81.1-1.11.0-1.01.00.0-0.30.2-0.10.4
Reaction time num false alarms0.20.32.3-0.30.3-0.20.30.3-0.30.3-0.3-0.30.2-0.0-0.80.70.00.00.1-0.2-0.20.20.8-0.80.91.50.1-0.30.61.4
Reaction time num false alarms AUC0.10.21.4-0.0-0.0-0.00.00.0-0.00.1-0.1-0.10.4-0.3-0.40.5-0.10.20.3-0.1-0.30.30.5-0.50.61.10.1-0.20.51.2
Reaction time trials correct on left0.10.31.40.2-0.10.6-0.5-0.60.1-0.40.40.40.9-0.90.5-0.5-0.0-0.00.20.4-0.70.7-0.60.6-0.51.20.10.0-0.2-0.9
Reaction time trials on left0.10.41.30.3-0.20.6-0.6-0.70.1-0.50.50.50.9-1.00.6-0.6-0.10.00.30.4-0.80.8-0.70.7-0.61.20.1-0.0-0.2-0.9
Reaction time mean0.00.10.20.2-0.20.2-0.2-0.20.3-0.20.20.20.1-0.10.00.0-0.30.30.30.1-0.40.40.0-0.00.0-0.20.2-0.20.30.1
Reaction time mean AUC0.00.10.20.3-0.30.3-0.3-0.40.4-0.40.40.40.2-0.20.2-0.1-0.30.30.30.3-0.30.3-0.20.2-0.2-0.40.1-0.10.2-0.2
Median of all reaction times0.20.30.90.6-0.60.6-0.6-0.60.6-0.60.60.60.7-0.60.5-0.3-0.50.60.60.6-1.01.0-0.40.4-0.4-0.10.4-0.40.40.0
Reaction time omissions0.40.72.10.6-0.50.7-0.7-0.70.4-0.70.70.70.8-0.91.3-0.6-0.20.20.20.6-1.31.3-1.41.4-1.40.10.10.0-0.2-1.0
Reaction time false alarm rate0.20.31.4-0.40.3-0.60.60.6-0.30.6-0.6-0.6-0.40.5-0.71.10.3-0.2-0.2-0.70.4-0.40.7-0.70.70.5-0.40.30.01.2
Reaction time premature initiation rate0.10.20.8-0.50.4-0.40.40.9-0.10.7-0.7-0.7-0.10.4-0.10.50.4-0.3-0.3-0.80.1-0.10.0-0.00.10.9-0.60.6-0.6-0.3
Reaction time premature initiations0.10.22.0-0.10.10.1-0.00.30.10.2-0.2-0.20.6-0.30.3-0.00.1-0.10.0-0.3-0.60.6-0.40.4-0.31.4-0.30.3-0.4-0.8
Std. dev. reaction times0.20.61.2-0.90.9-0.80.80.8-0.80.8-0.8-0.8-1.01.0-1.10.90.6-0.6-0.6-0.90.7-0.71.1-1.11.10.3-0.50.4-0.20.7
Reaction time trials completed0.10.41.30.3-0.20.6-0.6-0.70.1-0.50.50.50.9-1.00.6-0.6-0.10.00.30.4-0.80.8-0.70.7-0.61.20.1-0.0-0.2-0.9
Reaction time trials AUC0.10.41.00.4-0.30.7-0.6-0.70.2-0.50.50.50.9-1.00.6-0.6-0.10.10.30.5-0.80.8-0.70.7-0.61.00.2-0.1-0.1-0.9
Run reversals in cocaine runway, females0.20.21.3-0.50.5-0.50.50.7-0.70.6-0.6-0.6-0.20.3-0.10.50.5-0.5-0.7-0.5-0.10.1-0.10.1-0.11.2-0.30.3-0.20.2
Run reversals in cocaine runway, males0.20.21.0-0.10.1-0.10.10.1-0.10.1-0.1-0.1-0.50.5-0.40.20.4-0.40.0-0.21.0-1.00.5-0.50.5-0.7-0.50.6-0.7-0.6
Latency to leave start box in cocaine runway0.50.62.20.8-0.80.5-0.5-0.30.6-0.20.20.20.9-0.81.3-0.2-0.20.20.10.4-1.21.2-1.51.5-1.50.1-0.10.1-0.3-1.5
Latency to leave start box in cocaine runway, F0.20.31.10.3-0.30.0-0.10.20.10.2-0.2-0.20.5-0.50.70.20.1-0.1-0.20.0-1.01.0-0.90.9-0.90.6-0.20.2-0.2-1.0
Latency to leave start box in cocaine runway, M0.30.31.40.6-0.60.5-0.5-0.50.6-0.40.40.40.5-0.40.9-0.3-0.20.20.20.3-0.10.1-1.01.0-1.0-0.6-0.10.2-0.4-1.2
Std. dev. time between licks in bursts0.40.81.70.9-0.90.9-0.9-0.90.9-0.90.90.91.0-0.90.7-1.3-1.01.00.91.3-0.90.9-0.60.6-0.5-0.41.1-1.00.90.3
Total sessions with >9 infusions0.30.41.10.8-0.80.6-0.6-0.60.8-0.50.50.50.4-0.30.6-0.9-0.70.70.50.6-0.20.2-0.50.5-0.5-1.10.7-0.70.50.6
Short access day 1 total inactive lever presses0.20.31.60.6-0.60.2-0.3-0.40.5-0.40.40.4-0.10.1-0.4-0.6-0.60.60.60.40.3-0.30.6-0.60.6-1.30.6-0.60.61.0
Short access day 10 total inactive lever presses0.32.04.1-1.61.6-1.31.31.3-1.61.1-1.1-1.1-1.51.6-2.01.41.2-1.2-1.0-1.71.4-1.42.0-2.02.01.2-0.90.7-0.51.3
Short access day 1 total infusions0.10.10.6-0.10.1-0.30.20.3-0.10.3-0.3-0.3-0.40.6-0.40.20.1-0.1-0.1-0.50.4-0.40.4-0.40.4-0.6-0.10.1-0.00.8
Short access day 10 total infusions0.40.71.71.0-1.00.8-0.8-1.01.0-0.90.90.90.6-0.60.9-1.3-0.80.80.81.0-0.30.3-0.70.7-0.8-1.30.8-0.70.50.2
Short access total infusions0.71.03.11.3-1.31.1-1.1-1.11.2-1.11.11.10.8-0.70.8-1.4-1.11.11.11.0-0.60.6-0.50.5-0.6-1.81.1-1.00.80.4
Short access day 1 locomotion0.40.61.4-0.90.9-0.90.90.8-0.90.8-0.8-0.8-0.80.80.10.60.9-1.0-1.2-0.80.3-0.3-0.30.3-0.40.8-0.90.9-1.0-0.2
Short access day 10 total locomotion0.20.82.6-0.80.8-0.60.60.6-0.70.8-0.8-0.8-0.20.20.70.20.9-1.0-1.1-0.40.3-0.3-1.11.1-1.11.6-0.91.0-1.2-1.5
Short access total locomotion0.20.31.70.0-0.0-0.00.0-0.00.10.1-0.1-0.10.2-0.11.0-0.40.2-0.2-0.40.0-0.20.2-1.31.3-1.30.1-0.20.3-0.5-0.7
One hour access (0.3 mA shock)1.11.33.61.4-1.41.2-1.2-1.31.4-1.11.11.10.8-0.70.2-1.5-1.41.41.51.2-0.10.10.2-0.20.2-1.91.4-1.31.21.0
Compulsive drug intake0.20.20.9-0.30.3-0.30.30.4-0.30.3-0.3-0.3-0.40.4-0.80.50.2-0.2-0.0-0.50.7-0.70.9-0.90.90.1-0.20.2-0.00.4
One hour access (shock baseline)0.41.12.31.2-1.21.1-1.1-1.31.2-1.11.11.11.0-1.00.9-1.5-1.21.11.01.2-0.80.8-0.70.7-0.7-1.41.2-1.10.90.3
Social response proportion2.12.66.4-1.61.6-1.51.51.7-1.61.5-1.5-1.5-1.71.6-2.51.41.1-1.1-0.9-1.51.8-1.82.5-2.52.50.6-0.80.6-0.31.7
Social responses0.70.93.8-0.70.6-0.40.40.6-0.60.5-0.5-0.5-0.20.2-1.60.4-0.20.20.2-0.5-0.10.11.8-1.81.91.30.5-0.71.11.9
Social time0.30.41.0-0.60.6-0.70.70.9-0.50.9-0.9-0.9-0.40.4-0.90.90.3-0.2-0.3-1.00.4-0.40.9-0.90.90.7-0.40.20.00.3
Soleus weight2.06.09.72.6-2.62.7-2.7-2.72.7-2.62.62.62.6-2.63.1-2.6-2.12.12.02.4-2.32.3-3.03.0-2.9-1.91.7-1.51.1-1.7
Bone: stiffness0.40.81.81.0-1.00.9-0.9-1.00.9-1.01.01.01.1-1.00.9-0.6-0.80.80.80.7-1.41.4-0.80.8-0.8-0.50.7-0.70.70.0
Tibialis anterior weight7.525.633.55.5-5.55.6-5.6-5.55.5-5.55.55.55.6-5.53.6-5.8-5.85.75.75.5-5.25.2-2.72.6-2.5-3.85.8-5.65.31.4
Time to tail flick, vehicle, before self-admin0.10.10.4-0.20.2-0.50.40.4-0.30.3-0.3-0.3-0.20.00.10.30.4-0.4-0.5-0.5-0.30.3-0.20.2-0.20.0-0.40.4-0.4-0.6
Time to tail flick, vehicle, after self-admin0.40.81.80.9-0.90.8-0.8-1.00.8-0.90.90.90.9-0.91.3-1.0-0.60.50.41.1-0.90.9-1.31.3-1.3-0.60.6-0.50.2-0.9
Time to tail flick, test, before self-admin0.10.20.60.1-0.10.1-0.10.00.1-0.20.20.20.4-0.3-0.1-0.2-0.40.40.20.1-0.80.80.1-0.20.20.70.5-0.60.70.8
Time to tail flick, test, after self-admin0.40.44.4-0.30.30.3-0.2-0.2-0.3-0.20.20.20.5-0.80.3-0.2-0.00.0-0.20.6-1.51.5-0.50.5-0.32.10.4-0.50.6-0.1
Delta time to tail flick, vehicle, before/after SA0.30.40.80.6-0.60.8-0.8-0.80.5-0.60.60.60.5-0.40.9-0.8-0.30.30.30.8-0.20.2-0.80.8-0.8-0.30.3-0.20.0-0.6
Delta time to tail flick, test, before/after SA0.30.42.0-0.70.7-0.30.40.3-0.80.4-0.4-0.4-0.40.10.30.50.8-0.8-0.9-0.20.1-0.1-0.50.5-0.51.4-0.70.7-0.7-1.0
Tibia length1.74.97.02.6-2.62.6-2.6-2.62.6-2.62.62.62.4-2.42.3-1.8-2.12.12.31.8-2.02.0-2.12.0-2.0-2.31.5-1.41.2-1.1
Ambulatory time before self-admin0.41.13.3-1.31.3-1.11.11.0-1.21.1-1.1-1.1-1.00.9-1.21.11.0-1.0-1.0-1.20.8-0.81.0-1.01.11.8-0.90.8-0.60.2
Ambulatory time after self-admin0.10.10.20.1-0.10.2-0.2-0.40.2-0.30.30.3-0.0-0.3-0.2-0.1-0.30.30.30.2-0.50.50.3-0.30.3-0.30.3-0.30.40.4
Bone: tissue strength1.11.12.2-1.11.1-1.11.11.1-1.21.2-1.2-1.2-1.11.2-1.21.51.0-1.0-1.0-1.20.9-0.91.1-1.11.11.0-1.00.8-0.60.3
Total heroin consumption0.30.40.9-0.10.1-0.40.40.7-0.10.8-0.8-0.80.20.30.60.40.4-0.4-0.6-0.80.0-0.0-0.90.9-0.91.0-0.60.7-0.7-0.7
Bone: trabecular number0.20.41.40.6-0.60.6-0.6-0.60.6-0.60.60.60.5-0.31.1-0.3-0.10.10.30.1-0.10.1-1.11.1-1.2-0.7-0.30.4-0.6-0.7
Bone: trabecular spacing0.71.03.90.6-0.60.7-0.7-0.60.6-0.60.60.60.8-0.9-0.7-0.6-1.21.21.20.8-0.80.81.0-1.01.1-0.11.5-1.72.01.8
Bone: trabecular thickness0.40.62.1-0.30.3-0.20.20.3-0.30.2-0.2-0.2-0.10.21.00.50.8-0.8-0.8-0.6-0.20.2-1.31.4-1.40.7-1.11.2-1.3-1.5
Bone: trabecular tissue density2.54.310.8-2.22.2-2.12.12.0-2.22.0-2.0-2.0-2.11.9-3.22.01.4-1.3-1.4-2.01.3-1.33.2-3.23.31.5-0.80.50.02.6
Water consumed over 24 hours1.01.93.21.3-1.31.4-1.3-1.31.3-1.31.31.31.5-1.41.8-1.6-1.21.21.01.8-1.71.7-1.81.8-1.7-0.51.2-1.10.8-0.8
Number of responses in last shaping day1.62.14.01.6-1.61.4-1.5-1.41.6-1.31.31.31.8-1.41.4-1.6-1.51.51.41.4-2.02.0-1.31.3-1.2-1.01.4-1.31.1-0.4