Hub : Genes

Fermt3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb alternative TSS XM_006230811.5 0.18 0.11 2.0e-03 0.05 0.09 0.09 0.07 2.8e-02 3.5e-03 3.5e-03 8.9e-03
2 LHb alternative TSS NM_001127543.1 0.19 0.11 1.5e-03 0.07 0.09 0.1 0.08 1.1e-02 4.4e-03 3.0e-03 7.0e-03
3 LHb alternative TSS NM_001127543.1 0.19 0.11 1.0e-03 0.09 0.11 0.11 0.1 4.4e-03 1.4e-03 1.5e-03 2.7e-03
4 BLA intron excision ratio chr1_213636273_213636704 0.1 0.06 9.0e-04 0.01 0.03 0.03 0.02 6.9e-02 8.1e-03 1.5e-02 4.1e-02
5 BLA intron excision ratio chr1_213636270_213636704 0.1 0.06 9.4e-04 0.01 0.03 0.03 0.02 7.0e-02 8.3e-03 1.5e-02 4.0e-02
6 Liver gene expression Fermt3 0.03 0.02 3.7e-03 0.01 0.01 0.01 0.01 1.3e-02 9.0e-03 2.9e-02 8.0e-03
7 LHb alternative TSS XM_006230811.5 0.19 0.11 1.3e-03 0.07 0.12 0.12 0.11 1.1e-02 1.1e-03 1.0e-03 1.5e-03
8 NAcc gene expression Fermt3 0.01 0.01 6.8e-03 0.01 0.01 0.01 0.01 5.2e-03 1.0e-02 7.1e-03 3.4e-02
9 RMTg alternative polyA XM_039079706.2 0.13 0.08 9.5e-03 -0.01 0 -0.01 -0.01 5.0e-01 3.2e-01 7.2e-01 6.2e-01
10 RMTg alternative polyA XM_006230811.5 0.13 0.08 9.1e-03 -0.01 -0.01 -0.01 -0.01 9.2e-01 5.7e-01 9.6e-01 9.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.40.90.4-0.50.40.1-0.10.8-0.40.7-0.91.0
Area under the delay curve0.10.20.7-0.10.0-0.0-0.30.30.2-0.70.4-0.80.9
BMI with tail1.13.99.70.8-1.11.30.3-0.32.8-1.52.5-3.03.1
BMI without tail0.42.36.01.0-1.11.10.5-0.52.0-0.21.9-2.42.4
Body weight2.08.814.92.6-2.82.92.0-1.93.80.53.6-3.93.8
Weight adjusted by age0.61.62.31.3-1.41.51.5-1.51.50.91.3-0.80.7
Bone surface2.24.37.82.2-2.32.42.0-1.92.80.92.3-1.81.7
Bone volume0.40.82.11.0-1.01.10.8-0.81.4-0.00.9-0.70.7
Breakpoint value in progressive ratio session2.13.75.02.1-2.12.22.2-2.12.21.71.9-1.31.2
Number of licking bursts0.10.30.30.6-0.60.60.6-0.60.50.50.6-0.20.2
Context. condit. distance diff. score1.31.62.4-1.51.4-1.5-1.61.6-1.2-1.3-1.10.5-0.4
Locomotion velocity, session 10.20.20.90.1-0.2-0.1-0.30.4-0.0-0.10.5-0.80.9
Locomotion distance, session 10.40.51.90.3-0.40.1-0.30.30.4-0.40.7-1.31.4
Locomotion velocity, session 21.82.12.81.5-1.61.51.2-1.21.70.71.6-1.71.6
Locomotion distance, session 20.50.61.90.6-0.70.50.2-0.20.70.11.0-1.31.4
Locomotion velocity, session 31.61.95.2-1.41.2-1.3-1.81.9-0.8-2.3-0.6-0.50.6
Locomotion distance, session 30.10.10.3-0.40.3-0.3-0.50.5-0.1-0.60.1-0.30.3
Stereotopy head waving bouts, day 31.82.25.2-1.61.4-1.5-2.02.0-1.0-2.3-0.7-0.30.6
Stereotopy head waving duration, day 31.21.42.5-1.31.3-1.3-1.51.5-1.1-1.6-1.00.4-0.3
Locomotion velocity, session 71.21.32.9-1.31.2-1.2-1.51.5-0.8-1.7-0.90.2-0.0
Locomotion distance, session 70.30.40.8-0.50.4-0.5-0.80.8-0.2-0.90.2-0.70.9
Stereotopy head waving bouts, day 70.10.20.3-0.40.4-0.3-0.30.3-0.0-0.6-0.50.4-0.4
Stereotopy head waving duration, day 70.30.41.00.6-0.60.80.8-0.81.00.30.4-0.20.1
Locomotion velocity, session 81.21.42.61.2-1.31.10.8-0.81.10.91.4-1.61.6
Locomotion distance, session 80.50.81.7-0.90.8-0.9-1.31.3-0.5-1.2-0.4-0.30.4
Degree of sensitization distance0.30.41.0-0.50.4-0.5-0.80.8-0.1-1.0-0.1-0.50.6
Degree of sensitization stereotypy0.20.20.50.4-0.40.50.5-0.50.70.20.20.1-0.2
Conditioned locomotion1.31.52.21.2-1.31.21.1-1.01.40.91.5-1.31.2
Cocaine response after cond. corrected1.01.42.6-1.41.3-1.4-1.61.6-1.0-1.3-0.80.10.0
Cocaine response after cond. not corrected0.71.01.8-1.21.1-1.2-1.31.3-0.8-1.2-0.70.00.1
Cocaine response before conditioning0.70.81.51.0-0.91.11.2-1.20.90.90.6-0.1-0.0
Saline control response4.36.07.22.6-2.62.62.4-2.42.62.02.7-2.32.2
Bone: connectivity density1.52.33.91.5-1.61.61.2-1.22.00.51.8-1.71.7
Bone: cortical apparent density0.30.51.40.7-0.60.60.9-0.90.31.20.20.2-0.3
Bone: cortical area0.30.51.00.7-0.80.80.8-0.81.00.20.7-0.50.4
Bone: cortical porosity0.20.20.30.5-0.40.50.5-0.50.30.50.4-0.10.1
Bone: cortical porosity0.60.60.80.8-0.80.90.9-0.90.80.70.8-0.60.5
Bone: cortical thickness3.55.87.22.6-2.62.62.7-2.72.42.42.4-1.81.6
Bone: cortical thickness0.91.11.91.0-1.00.90.8-0.70.90.81.2-1.41.4
Bone: cortical tissue density0.40.71.90.9-0.80.81.1-1.10.51.40.40.0-0.2
Condit. Reinf. active minus inactive responses0.10.10.20.4-0.40.40.4-0.40.50.20.2-0.40.3
Condit. Reinf. active-inactive response ratio0.20.20.50.4-0.40.40.6-0.60.30.70.00.1-0.2
Condit. Reinf. active responses0.00.10.3-0.20.2-0.1-0.20.20.1-0.5-0.30.0-0.0
Condit. Reinf. inactive responses0.50.71.9-0.90.9-0.8-1.01.0-0.5-1.4-0.70.3-0.2
Incentive salience index mean0.20.20.50.3-0.40.40.3-0.30.6-0.10.5-0.70.6
Condit. Reinf. lever presses0.10.20.40.2-0.30.40.2-0.20.7-0.40.5-0.50.5
Condit. Reinf. active minus inactive responses0.20.40.8-0.40.5-0.5-0.30.3-0.4-0.3-0.90.9-0.9
Condit. Reinf. active-inactive response ratio1.21.93.2-1.31.4-1.4-1.31.3-1.2-1.3-1.81.5-1.5
Condit. Reinf. active responses0.00.10.10.2-0.20.20.3-0.30.20.2-0.00.3-0.3
Condit. Reinf. inactive responses0.81.11.91.0-1.11.11.1-1.11.00.91.4-1.00.9
Condit. Reinf. lever presses0.81.11.91.2-1.21.31.2-1.21.40.71.1-0.60.4
Condit. Reinf. lever reinforcers received0.20.20.50.5-0.50.60.7-0.70.50.50.20.1-0.2
Conditioned reinforcement - actives0.10.41.7-0.20.3-0.20.0-0.1-0.4-0.1-0.41.3-1.3
Conditioned reinforcement - inactives1.64.46.3-2.32.3-2.0-1.71.7-1.9-1.9-2.02.5-2.5
Conditioned locomotion7.410.912.6-3.53.6-3.5-3.13.1-3.5-2.6-3.43.4-3.3
Patch foraging indifference point 0 sec0.00.10.3-0.30.3-0.2-0.10.1-0.4-0.5-0.20.2-0.2
Patch foraging indifference point AUC1.22.94.51.9-1.82.02.1-2.11.91.81.3-0.60.4
Delay disc. indifference point, 0s delay0.50.61.2-0.50.4-0.5-1.01.0-0.2-1.00.1-0.91.1
Delay disc. indifference point, 16s delay0.71.01.7-1.21.1-0.9-0.80.8-0.9-1.3-1.00.8-0.8
Delay disc. indifference point, 2s delay0.20.20.7-0.40.4-0.4-0.60.6-0.1-0.8-0.2-0.20.3
Delay disc. indifference point, 24s delay0.00.10.2-0.0-0.10.10.1-0.10.1-0.20.2-0.40.4
Delay disc. indifference point, 4s delay0.30.31.4-0.1-0.0-0.0-0.40.40.3-0.40.5-1.11.2
Delay disc. indifference point, 8s delay0.10.21.00.1-0.20.1-0.20.20.2-0.30.7-0.91.0
Indifference point function ln k3.09.012.5-3.43.3-3.5-3.53.5-3.3-3.1-2.61.4-1.1
Indifference point function log k3.09.012.5-3.43.3-3.5-3.53.5-3.3-3.1-2.61.4-1.1
Patch foraging total patch changes 0 sec0.00.00.0-0.00.00.00.1-0.1-0.2-0.10.1-0.1-0.0
Patch foraging total patch changes 12 sec3.85.06.72.3-2.42.62.5-2.52.31.62.6-1.81.6
Patch foraging total patch changes 18 sec0.40.91.61.0-1.01.21.2-1.30.90.90.7-0.40.2
Patch foraging total patch changes 24 sec0.72.43.21.5-1.61.81.8-1.81.80.91.8-1.31.1
Patch foraging total patch changes 6 sec0.71.31.91.0-1.11.10.9-0.91.30.41.4-1.41.3
Patch foraging time to switch 0 sec0.20.81.20.9-1.00.90.6-0.61.1-0.11.1-1.11.1
Patch foraging water rate 0 sec1.14.05.4-2.32.3-2.1-1.71.7-2.3-1.3-2.12.1-2.1
Patch foraging water rate 12 sec1.87.410.1-3.13.1-3.2-2.82.8-3.1-1.9-2.82.1-2.0
Patch foraging water rate 18 sec1.22.74.0-2.01.9-2.0-2.02.0-1.6-1.7-1.20.7-0.6
Patch foraging water rate 24 sec2.33.34.8-2.22.1-2.1-1.91.9-1.8-1.5-1.81.4-1.3
Patch foraging water rate 6 sec2.43.65.2-2.22.2-2.2-2.02.0-2.3-1.5-1.91.1-1.0
Seeking ratio, delayed vs. immediate footshock0.20.20.3-0.60.5-0.5-0.50.5-0.6-0.5-0.60.3-0.3
Distance traveled before self-admin0.10.30.50.5-0.60.70.6-0.60.70.20.5-0.20.1
Distance traveled after self-admin0.30.51.10.7-0.70.70.9-0.90.61.10.20.1-0.2
Extensor digitorum longus weight6.124.332.75.2-5.35.34.6-4.65.73.45.4-4.94.6
Bone: elastic displacement0.20.20.8-0.50.5-0.6-0.50.5-0.90.1-0.50.2-0.2
Bone: elastic work1.41.83.01.2-1.31.21.0-1.01.30.91.7-1.71.7
Bone: endosteal estimation1.53.78.5-2.01.9-2.0-2.52.5-1.4-2.9-1.50.5-0.3
Bone: endosteal perimeter2.15.010.3-2.42.3-2.3-2.62.7-1.7-3.2-2.01.2-1.0
Epididymis fat weight2.613.016.3-4.04.0-3.8-3.63.6-3.4-3.8-3.73.1-2.9
Delta time in closed arm before/after self-admin0.60.52.20.3-0.40.2-0.10.10.4-0.20.6-1.51.5
Delta time in open arm before/after self-admin0.40.40.80.5-0.40.70.9-0.90.60.70.30.6-0.7
Diff in mean of infusions in LGA sessions0.40.71.10.9-0.91.01.0-1.01.00.50.7-0.80.7
Delay discount exponential model param0.10.20.7-0.00.1-0.10.1-0.1-0.30.5-0.50.8-0.9
Extinction: sum of active levers before priming1.42.13.21.6-1.61.61.4-1.41.81.21.4-1.31.3
Active lever presses in extinction session 62.72.73.91.8-1.81.91.9-1.92.01.61.4-0.90.7
Bone: final force1.42.23.91.5-1.61.61.3-1.32.00.51.7-1.61.5
Bone: final moment1.32.13.71.4-1.51.61.3-1.21.90.41.7-1.61.5
Food consumed during 24 hour testing period0.10.20.60.3-0.20.30.6-0.60.10.7-0.10.7-0.8
Glucose3.35.28.1-2.62.5-2.5-2.82.8-2.1-2.8-1.80.9-0.6
Heart weight1.21.93.9-1.31.2-1.4-2.02.0-0.7-1.8-0.5-0.81.1
Delay discount hyperbolic model param0.10.20.70.00.1-0.00.2-0.2-0.30.5-0.40.8-0.8
Intermittent access intake day 1-15 change0.31.84.3-1.21.3-1.1-0.70.7-1.4-0.5-1.42.0-2.1
Intermittent access intake escalation0.31.64.3-1.11.2-1.0-0.60.5-1.3-0.3-1.22.0-2.1
Intermittent access intake escalation 20.91.64.0-1.11.2-1.0-0.70.6-1.2-0.5-1.31.9-2.0
Intermitt. access day 1 inactive lever presses0.00.20.7-0.20.2-0.3-0.10.1-0.50.2-0.60.8-0.8
Intermitt. access day 15 inactive lever presses0.84.55.4-2.22.2-2.1-1.91.9-2.0-2.2-2.32.1-2.1
Intermitt. access escalation Index0.82.43.4-1.81.8-1.7-1.61.6-1.8-1.3-1.51.2-1.1
Intermittent access day 1 total infusions2.36.813.1-2.92.8-2.8-3.13.1-1.9-3.6-2.11.4-1.2
Intermittent access day 15 total infusions4.09.911.7-3.43.4-3.3-3.13.1-2.9-3.1-3.13.1-2.9
Intermittent access terminal intake (last 3 days)5.39.312.9-3.43.4-3.2-3.23.1-2.5-3.6-2.72.6-2.5
Intermittent access total infusions6.67.911.9-3.13.1-3.0-3.13.1-2.3-3.5-2.52.1-1.9
Intermittent access day 1 locomotion2.44.47.7-2.42.3-2.3-2.52.5-1.6-2.8-1.71.2-1.0
Intermittent access day 15 total locomotion2.17.99.8-3.13.1-2.9-2.72.7-2.4-3.0-2.62.8-2.7
Intermittent access total locomotion10.712.918.3-4.04.0-3.7-3.73.7-3.0-4.3-3.23.1-2.9
Intermittent access standard deviation0.42.22.8-1.51.5-1.5-1.31.3-1.6-1.0-1.71.6-1.6
Left kidney weight0.42.94.8-1.91.9-1.8-2.02.0-1.4-2.2-1.41.0-0.8
Right kidney weight0.21.72.6-1.51.5-1.4-1.41.4-1.1-1.6-1.11.0-0.9
Cocaine induced anxiety0.00.10.20.2-0.20.20.3-0.30.20.3-0.20.4-0.4
Post-drug Anxiety0.30.30.50.7-0.70.70.6-0.60.70.40.4-0.30.3
Baseline Anxiety0.30.51.10.6-0.60.50.4-0.40.60.20.9-1.01.0
Tail length0.63.14.72.0-2.01.81.9-1.91.62.21.5-1.41.2
Length with tail1.98.510.53.2-3.23.12.8-2.72.92.62.9-2.92.7
Length without tail1.15.97.42.5-2.62.52.2-2.12.41.72.7-2.72.6
Times rat made contact with spout1.01.11.81.2-1.21.01.1-1.10.81.31.1-0.80.7
Lifetime Intake4.65.79.1-2.72.6-2.6-2.82.8-2.0-3.0-2.01.5-1.3
Liver weight, left0.61.11.9-1.11.1-1.2-1.41.4-1.2-0.9-0.90.3-0.2
Liver weight, right1.72.95.2-1.91.8-2.0-2.32.3-1.8-2.0-1.00.10.2
Locomotor activity0.91.32.3-1.41.4-1.4-1.31.3-1.5-0.8-0.90.6-0.5
Locomotor testing distance0.71.82.8-1.61.6-1.6-1.61.6-1.7-1.0-1.10.4-0.3
Locomotor testing rearing0.51.93.0-1.51.5-1.6-1.71.7-1.7-1.1-1.20.4-0.3
Locomotion in novel chamber5.57.49.4-3.13.0-2.9-2.72.7-2.8-2.6-2.62.5-2.3
Locomotion in novel chamber post-restriction1.54.66.1-2.12.2-2.2-2.02.0-2.3-1.6-2.52.3-2.2
Fecal boli incidents, locomotor time 10.10.10.60.1-0.00.10.3-0.30.00.2-0.40.7-0.8
Change in fecal boli incidents, locomotor task0.20.20.8-0.20.1-0.3-0.50.5-0.0-0.40.4-0.70.9
Time >=10cm from walls, locomotor time 11.21.51.7-1.21.2-1.2-1.31.3-0.9-1.2-1.31.3-1.1
Bouts of movement, locomotor time 12.43.16.61.8-1.71.82.4-2.41.22.61.20.2-0.5
Total resting periods, locomotor time 11.82.14.61.4-1.31.52.0-2.00.92.10.90.4-0.7
Rest time, locomotor task time 11.01.62.7-1.21.3-1.3-0.90.9-1.4-0.6-1.41.6-1.6
Distance moved, locomotor task time 10.10.30.90.2-0.30.3-0.00.00.6-0.30.7-0.91.0
Vertical activity count, locomotor time 10.11.01.7-1.11.1-1.2-1.31.3-1.0-1.1-0.70.4-0.3
Time >=10cm from walls, locomotor time 20.10.31.00.2-0.10.20.5-0.50.10.7-0.40.9-1.0
Bouts of movement, locomotor time 20.10.50.90.7-0.70.80.9-0.90.70.70.5-0.20.1
Total resting periods, locomotor time 20.00.20.30.4-0.40.50.6-0.60.40.40.2-0.0-0.1
Rest time, locomotor task time 21.83.03.8-1.91.9-2.0-1.91.9-1.9-1.6-1.51.4-1.2
Distance moved, locomotor task time 21.51.92.71.5-1.51.51.6-1.61.41.61.2-0.80.7
Vertical activity count, locomotor time 20.10.20.70.4-0.40.30.4-0.40.10.90.3-0.30.3
Light reinforcement 10.00.10.40.10.0-0.10.1-0.1-0.50.4-0.20.5-0.6
Light reinforcement 21.22.74.4-1.41.5-1.5-1.21.2-1.7-1.4-1.92.1-2.1
Bone: marrow area1.63.98.8-2.12.0-2.1-2.52.6-1.5-3.0-1.50.5-0.2
Bone: maximum diameter0.00.10.4-0.00.00.1-0.0-0.00.3-0.6-0.10.2-0.3
Bone: maximum force1.12.34.81.4-1.51.61.1-1.12.2-0.11.7-1.71.7
Bone: maximum moment1.12.14.51.3-1.41.51.1-1.12.1-0.11.7-1.71.7
Mean time between licks in bursts0.21.02.20.8-0.90.80.6-0.60.70.71.4-1.51.5
Mean num. licks in bursts0.00.00.1-0.10.1-0.2-0.10.1-0.30.1-0.20.0-0.0
Cd content in liver1.41.52.8-1.21.3-1.1-0.80.8-1.0-0.9-1.61.7-1.6
Co content in liver0.20.20.6-0.30.4-0.5-0.20.2-0.80.5-0.40.4-0.4
Cu content in liver0.00.00.10.1-0.00.00.2-0.2-0.10.3-0.30.3-0.3
Fe content in liver0.10.10.30.4-0.40.30.2-0.20.50.20.2-0.50.5
K content in liver0.70.72.00.5-0.60.60.2-0.21.0-0.30.9-1.41.4
Mg content in liver0.40.41.0-0.70.6-0.6-0.80.8-0.3-1.0-0.1-0.40.5
Mn content in liver1.92.13.01.6-1.61.71.7-1.71.70.91.4-0.90.7
Na content in liver0.30.30.50.6-0.60.60.6-0.60.70.20.6-0.60.5
Rb content in liver1.61.92.9-1.51.5-1.6-1.71.7-1.3-1.2-1.40.6-0.4
Se content in liver0.40.41.2-0.50.6-0.4-0.30.3-0.4-0.3-1.01.1-1.1
Sr content in liver2.72.43.41.7-1.71.81.9-1.91.51.51.5-0.80.6
Zn content in liver0.40.50.60.8-0.80.80.8-0.80.80.60.7-0.70.5
Bone: minimum diameter1.73.27.6-1.91.8-1.8-2.22.2-1.3-2.8-1.40.6-0.4
Time in familiar zone, hab. session 10.30.41.1-0.80.7-0.6-0.70.7-0.4-1.0-0.30.1-0.1
Time in novel zone, hab. session 10.10.10.2-0.10.1-0.3-0.40.4-0.40.1-0.1-0.20.3
Total zone transitions, hab. session 10.40.50.80.9-0.90.70.7-0.70.70.80.7-0.50.5
Total locomotion distance, hab. session 10.60.91.6-0.90.9-1.1-1.31.3-0.9-1.0-0.80.3-0.2
Locomotion velocity, hab. session 10.10.20.4-0.30.3-0.5-0.60.6-0.4-0.4-0.30.00.0
Time in familiar zone, hab. session 20.40.41.10.5-0.50.50.4-0.40.50.40.9-1.01.0
Time in novel zone, hab. session 20.10.10.1-0.20.2-0.2-0.20.2-0.2-0.4-0.40.3-0.4
Total zone transitions, hab. session 20.70.92.30.7-0.80.70.3-0.31.0-0.21.3-1.51.5
Total locomotion distance, hab. session 20.40.51.4-0.50.4-0.6-0.90.9-0.3-1.20.1-0.70.8
Locomotion velocity, hab. session 20.50.71.8-0.80.7-0.8-1.11.1-0.5-1.4-0.2-0.30.4
Novel to familiar place preference ratio0.50.61.30.8-0.81.01.0-1.01.20.70.50.0-0.1
Novelty place preference0.20.30.60.5-0.40.60.7-0.70.80.50.10.3-0.4
Time in novel zone, NPP test0.20.20.60.4-0.40.50.6-0.60.70.40.20.1-0.2
Total zone transitions, NPP test1.42.12.71.5-1.61.51.2-1.21.70.91.6-1.51.5
Total locomotion distance, NPP test0.10.20.5-0.20.1-0.3-0.60.6-0.1-0.70.1-0.50.6
Locomotion velocity, NPP test0.00.10.2-0.0-0.0-0.1-0.30.3-0.1-0.40.1-0.30.4
Intraocular pressure0.91.55.4-0.80.9-0.6-0.00.0-0.90.3-1.42.2-2.3
Delta distance traveled before/after self-admin0.00.10.40.1-0.1-0.00.1-0.1-0.10.6-0.1-0.10.1
Delta ambulatory time before/after self-admin0.10.10.70.3-0.30.10.1-0.10.00.80.0-0.30.4
Parametrial fat weight3.99.212.3-3.43.4-3.2-3.33.3-2.9-3.5-2.72.2-2.0
Pavlov. Cond. lever latency0.20.20.4-0.30.4-0.5-0.40.4-0.60.1-0.60.6-0.6
Pavlov. Cond. magazine entry latency0.10.20.40.3-0.30.40.3-0.30.7-0.30.5-0.40.4
Pavlov. Cond. change in total contacts0.10.10.4-0.00.00.10.3-0.30.2-0.1-0.20.5-0.6
Pavlov. Cond. index score0.20.30.50.5-0.50.60.7-0.70.60.30.5-0.20.1
Pavlov. Cond. latency score0.10.10.30.3-0.30.40.4-0.40.50.10.5-0.30.2
Pavlov. Cond. lever contacts0.10.10.30.1-0.20.20.1-0.10.5-0.30.5-0.60.6
Pavlov. Cond. magazine entry number0.40.50.9-0.70.6-0.8-1.01.0-0.7-0.7-0.4-0.10.3
Pavlov. Cond. intertrial magazine entries0.60.82.4-0.60.7-0.5-0.10.1-0.80.2-1.21.4-1.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.6-0.60.80.8-0.80.80.30.7-0.30.2
Pavlov. Cond. response bias0.20.20.40.4-0.40.60.7-0.70.60.30.4-0.0-0.1
Pavlov. Cond. lever latency0.20.20.5-0.50.5-0.6-0.60.6-0.7-0.2-0.50.1-0.0
Pavlov. Cond. magazine entry latency3.14.55.72.3-2.32.42.2-2.22.41.72.2-1.61.5
Pavlov. Cond. change in total contacts0.40.91.61.0-1.01.21.3-1.31.20.70.50.0-0.2
Pavlov. Cond. index score1.21.93.01.5-1.51.61.6-1.61.71.01.3-0.80.6
Pavlov. Cond. latency score0.81.42.31.3-1.31.41.3-1.31.50.81.1-0.60.5
Pavlov. Cond. lever contacts0.20.30.60.6-0.60.70.8-0.80.80.40.5-0.1-0.0
Pavlov. Cond. magazine entry number4.96.38.5-2.82.8-2.9-2.82.8-2.9-2.1-2.41.7-1.4
Pavlov. Cond. intertrial magazine entries0.51.11.5-1.11.2-1.1-0.90.9-1.1-0.8-1.21.1-1.0
Pavlov. Cond. lever-magazine prob. diff.1.62.43.71.7-1.71.91.8-1.81.91.21.5-0.90.7
Pavlov. Cond. response bias1.21.72.61.4-1.41.61.5-1.51.60.91.4-0.80.7
Time in closed arm before self-admin0.30.61.0-0.80.8-0.7-0.60.6-0.5-0.7-0.71.0-1.0
Time in closed arm after self-admin0.50.50.8-0.80.8-0.8-0.90.9-0.7-0.9-0.60.2-0.1
Time in open arm before self-admin0.30.41.80.1-0.1-0.1-0.30.4-0.30.00.4-1.21.3
Time in open arm after self-admin0.50.50.80.7-0.70.70.7-0.70.60.90.9-0.60.6
Bone: periosteal estimation0.30.73.1-0.80.8-0.7-1.01.0-0.2-1.8-0.50.10.0
Bone: periosteal perimeter0.10.21.3-0.30.3-0.2-0.40.50.1-1.1-0.1-0.10.1
Bone: post-yield work0.50.95.0-0.80.7-0.6-1.01.00.2-2.2-0.3-0.00.2
Progressive ratio test 1 active lever presses0.40.81.2-1.01.0-0.9-1.01.0-0.7-1.1-0.80.8-0.7
Progressive ratio test 1 breakpoint0.40.71.1-0.90.9-0.9-0.90.9-0.6-1.1-0.70.8-0.7
Progressive ratio test 1 inactive lever presses0.10.20.3-0.60.5-0.3-0.30.3-0.1-0.60.10.5-0.5
Progressive ratio test 2 active lever presses3.44.85.6-2.42.4-2.2-2.02.0-1.9-2.3-2.22.2-2.1
Progressive ratio test 2 breakpoint3.74.85.7-2.42.4-2.2-2.02.0-1.9-2.3-2.22.2-2.2
Progressive ratio test 2 inactive lever presses3.912.315.1-3.93.9-3.6-3.23.2-3.3-3.4-3.53.6-3.5
Incentive Sensitization - Responses0.20.41.6-0.70.7-0.5-0.60.6-0.2-1.3-0.50.5-0.5
Incentive Sensitization - Breakpoint0.30.72.0-1.00.9-0.8-0.80.8-0.4-1.4-0.80.7-0.8
Sum of active levers in priming session hrs 5-61.71.63.11.2-1.01.21.7-1.80.91.70.11.0-1.3
Progressive ratio0.20.51.00.6-0.70.70.3-0.31.0-0.10.8-0.91.0
Food seeking constrained by brief footshock0.10.20.50.3-0.30.20.1-0.10.30.20.5-0.60.7
Seeking ratio, punishment vs. effort0.20.51.1-0.80.8-0.9-0.80.8-1.1-0.3-0.60.3-0.3
Retroperitoneal fat weight8.337.147.6-6.96.8-6.7-6.66.6-6.3-6.0-5.84.4-3.9
Reaction time number correct0.10.50.70.7-0.70.80.8-0.80.80.90.7-0.40.3
Reaction time mean minus median0.53.34.62.1-2.02.12.1-2.12.11.81.6-0.80.6
Reaction time mean minus median AUC0.32.33.21.7-1.61.71.8-1.81.81.71.4-0.50.4
Reaction time num false alarms0.10.20.3-0.30.3-0.4-0.40.5-0.50.00.0-0.50.6
Reaction time num false alarms AUC0.10.31.00.4-0.40.30.2-0.20.20.60.7-1.01.0
Reaction time trials correct on left0.10.50.70.7-0.70.80.8-0.80.80.90.7-0.40.3
Reaction time trials on left0.20.60.90.8-0.80.90.9-0.90.90.90.8-0.50.4
Reaction time mean0.00.10.40.1-0.00.10.2-0.20.10.3-0.20.6-0.6
Reaction time mean AUC0.00.10.5-0.00.10.00.2-0.20.00.2-0.30.7-0.7
Median of all reaction times0.20.40.7-0.60.6-0.5-0.40.4-0.5-0.3-0.60.8-0.8
Reaction time omissions1.01.62.31.3-1.31.51.5-1.51.31.21.4-0.60.5
Reaction time false alarm rate0.10.20.4-0.30.3-0.4-0.50.5-0.4-0.2-0.0-0.50.6
Reaction time premature initiation rate2.64.17.12.0-2.11.91.5-1.51.91.22.5-2.72.6
Reaction time premature initiations2.16.58.72.6-2.72.62.3-2.32.52.12.9-2.72.6
Std. dev. reaction times0.31.01.91.2-1.11.11.3-1.31.01.40.50.1-0.2
Reaction time trials completed0.20.60.90.8-0.80.90.9-0.90.90.90.8-0.50.4
Reaction time trials AUC0.10.40.60.6-0.60.60.7-0.70.70.70.7-0.40.4
Run reversals in cocaine runway, females0.80.93.30.1-0.30.1-0.40.40.6-0.90.9-1.71.8
Run reversals in cocaine runway, males0.00.00.1-0.30.3-0.3-0.20.2-0.2-0.1-0.10.2-0.1
Latency to leave start box in cocaine runway0.30.40.7-0.40.4-0.7-0.80.9-0.5-0.6-0.70.3-0.2
Latency to leave start box in cocaine runway, F0.00.00.2-0.00.1-0.2-0.30.3-0.10.0-0.50.2-0.2
Latency to leave start box in cocaine runway, M0.20.20.4-0.20.2-0.4-0.60.6-0.3-0.5-0.2-0.10.2
Std. dev. time between licks in bursts0.10.21.00.1-0.20.0-0.10.1-0.00.10.7-0.91.0
Total sessions with >9 infusions0.30.41.1-0.60.5-0.6-0.80.8-0.2-1.1-0.3-0.00.2
Short access day 1 total inactive lever presses2.04.05.1-2.22.2-2.2-2.22.2-2.1-2.0-1.91.3-1.2
Short access day 10 total inactive lever presses0.10.40.7-0.50.5-0.7-0.60.6-0.90.1-0.80.5-0.4
Short access day 1 total infusions1.53.14.4-1.91.9-2.0-2.12.1-1.6-2.1-1.61.0-0.8
Short access day 10 total infusions1.42.35.6-1.61.5-1.6-2.02.0-1.0-2.4-0.90.4-0.2
Short access total infusions1.31.94.1-1.41.4-1.5-1.91.9-0.9-2.0-0.80.10.1
Short access day 1 locomotion1.42.33.0-1.71.7-1.7-1.71.7-1.3-1.7-1.21.1-1.0
Short access day 10 total locomotion0.52.13.9-1.71.7-1.5-1.61.6-1.1-2.0-1.11.1-1.0
Short access total locomotion2.03.15.0-2.01.9-1.9-2.02.0-1.4-2.2-1.41.2-1.1
One hour access (0.3 mA shock)7.59.011.3-3.43.3-3.2-3.03.0-3.0-3.0-2.82.6-2.4
Compulsive drug intake2.74.05.12.2-2.22.02.0-2.01.52.31.7-2.01.9
One hour access (shock baseline)4.511.714.2-3.83.8-3.6-3.43.3-3.3-3.3-3.13.4-3.2
Social response proportion0.40.50.80.7-0.80.90.9-0.90.90.40.6-0.40.4
Social responses0.50.71.10.8-0.81.01.0-1.00.80.90.7-0.50.4
Social time0.40.60.80.8-0.80.90.9-0.90.80.90.8-0.60.6
Soleus weight3.510.413.6-3.53.5-3.6-3.33.3-3.7-2.6-3.42.6-2.4
Bone: stiffness0.81.53.11.3-1.41.41.2-1.21.80.41.3-0.90.9
Tibialis anterior weight8.730.039.05.9-6.06.15.7-5.76.24.55.7-4.54.1
Time to tail flick, vehicle, before self-admin0.10.20.7-0.10.00.1-0.20.20.6-0.80.4-0.50.5
Time to tail flick, vehicle, after self-admin0.71.44.20.6-0.80.80.3-0.21.4-0.31.6-1.92.0
Time to tail flick, test, before self-admin2.52.86.6-2.11.9-1.8-2.12.1-1.2-2.6-0.80.10.0
Time to tail flick, test, after self-admin0.10.10.20.3-0.30.40.4-0.40.40.50.30.1-0.1
Delta time to tail flick, vehicle, before/after SA0.80.81.80.8-0.80.80.5-0.50.90.51.1-1.31.3
Delta time to tail flick, test, before/after SA2.63.27.62.0-1.91.92.4-2.41.22.80.80.2-0.5
Tibia length0.51.42.81.3-1.21.41.6-1.71.41.00.60.2-0.5
Ambulatory time before self-admin0.10.20.30.4-0.40.60.6-0.60.60.20.30.2-0.3
Ambulatory time after self-admin0.20.30.8-0.40.4-0.4-0.20.2-0.40.1-0.80.9-0.9
Bone: tissue strength0.00.10.2-0.10.1-0.10.0-0.0-0.20.1-0.30.4-0.4
Total heroin consumption5.86.98.42.9-2.92.92.9-2.92.92.72.5-1.71.5
Bone: trabecular number0.20.40.90.5-0.60.60.4-0.41.0-0.20.7-0.60.6
Bone: trabecular spacing0.10.10.4-0.30.3-0.4-0.20.2-0.60.2-0.30.2-0.1
Bone: trabecular thickness0.60.81.0-1.01.0-1.0-1.01.0-0.9-0.9-0.90.6-0.5
Bone: trabecular tissue density2.44.36.2-2.02.1-2.1-1.71.7-2.5-0.9-2.42.4-2.3
Water consumed over 24 hours1.12.13.51.7-1.61.51.7-1.71.31.91.4-0.80.7
Number of responses in last shaping day0.00.00.10.1-0.10.10.1-0.10.10.30.3-0.30.2