Fermt3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb alternative TSS XM_006230811.4 0.19 0.12 2.1e-03 0.08 0.1 0.1 0.07 6.3e-03 2.1e-03 2.3e-03 8.0e-03
2 LHb alternative TSS XM_006230811.4 0.19 0.12 2.0e-03 0.09 0.1 0.09 0.09 3.7e-03 2.0e-03 3.8e-03 4.1e-03
3 BLA intron excision ratio chr1_204207062_204207496 0.09 0.06 9.1e-04 0.01 0.04 0.01 0.03 4.8e-02 2.8e-03 8.4e-02 1.5e-02
4 BLA intron excision ratio chr1_204207065_204207496 0.1 0.06 8.1e-04 0.02 0.04 0.01 0.03 4.6e-02 2.5e-03 7.9e-02 1.2e-02
5 IL isoform ratio XM_006230811.4 0.15 0.1 8.3e-03 0.04 0.07 0.09 0.08 3.3e-02 7.6e-03 4.3e-03 4.8e-03
6 LHb alternative TSS NM_001127543.1 0.2 0.12 1.3e-03 0.09 0.1 0.13 0.09 4.5e-03 2.0e-03 5.9e-04 3.2e-03
7 LHb alternative TSS NM_001127543.1 0.2 0.12 1.4e-03 0.1 0.11 0.12 0.09 2.2e-03 1.8e-03 9.0e-04 3.9e-03
8 RMTg alternative polyA XM_039079706.1 0.13 0.08 7.9e-03 -0 0.04 -0 -0 3.7e-01 2.6e-02 3.6e-01 3.5e-01
9 RMTg alternative polyA XM_006230811.4 0.13 0.08 7.7e-03 -0 0.03 0 0 3.4e-01 4.6e-02 2.6e-01 3.3e-01
10 BLA alternative polyA XM_006230811.4 0.1 0.07 5.6e-03 0 -0 -0 -0 2.1e-01 4.5e-01 5.7e-01 4.6e-01
11 BLA alternative polyA XM_039079706.1 0.11 0.07 4.0e-03 0 -0 -0 -0 1.8e-01 3.8e-01 5.8e-01 3.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.71.23.8-0.2-0.20.0-0.01.2-1.3-1.5-0.50.4-1.91.9
Area under the delay curve0.20.20.50.20.20.4-0.4-0.3-0.5-0.6-0.50.5-0.70.7
BMI with tail3.812.427.5-1.5-1.6-0.80.83.0-4.8-5.2-2.82.7-5.25.2
BMI without tail2.55.29.8-1.3-1.4-0.90.92.0-2.9-3.0-2.32.3-3.13.1
Body weight3.614.927.1-3.2-3.3-2.72.73.9-5.1-5.2-3.83.7-4.04.0
Weight adjusted by age1.21.42.7-1.6-1.6-1.61.60.7-1.1-1.1-1.01.0-0.50.5
Bone surface3.05.38.9-2.1-1.9-1.71.73.0-2.8-3.0-1.31.2-2.82.8
Bone volume1.22.04.7-0.9-0.8-0.70.61.9-1.7-2.0-0.20.1-2.22.2
Breakpoint value in progressive ratio session2.22.54.6-2.0-1.9-2.02.02.1-1.4-1.3-1.11.1-0.60.6
Number of licking bursts0.10.10.3-0.5-0.5-0.50.50.1-0.1-0.0-0.20.2-0.10.1
Context. condit. distance diff. score1.01.22.41.51.51.6-1.6-1.40.60.50.7-0.7-0.00.0
Locomotion velocity, session 10.50.61.70.10.00.3-0.30.6-1.3-1.3-0.70.7-0.80.8
Locomotion distance, session 11.41.85.2-0.0-0.10.2-0.21.0-2.2-2.3-1.01.0-1.91.9
Locomotion velocity, session 22.83.27.1-1.5-1.5-1.31.31.9-2.6-2.7-1.71.6-1.41.4
Locomotion distance, session 21.01.33.1-0.5-0.6-0.30.31.1-1.8-1.7-1.31.3-1.31.3
Locomotion velocity, session 31.72.04.21.51.41.8-1.8-1.3-0.7-1.00.1-0.1-2.02.0
Locomotion distance, session 30.20.20.40.40.40.5-0.5-0.1-0.5-0.6-0.10.1-0.50.5
Stereotopy head waving bouts, day 31.82.23.91.71.62.0-2.0-1.5-0.3-0.50.2-0.2-2.02.0
Stereotopy head waving duration, day 31.01.22.41.51.41.6-1.6-1.50.50.40.7-0.7-0.70.7
Locomotion velocity, session 71.21.32.51.41.41.6-1.6-1.30.1-0.10.6-0.6-1.21.2
Locomotion distance, session 70.40.61.30.80.70.9-0.9-1.10.0-0.0-0.40.4-1.01.0
Stereotopy head waving bouts, day 70.30.40.80.60.60.6-0.60.3-0.2-0.50.9-0.9-0.50.5
Stereotopy head waving duration, day 71.01.23.5-0.9-0.9-0.80.81.9-1.5-1.7-0.30.3-0.80.8
Locomotion velocity, session 81.72.04.0-1.0-1.1-0.80.92.0-2.0-1.8-1.51.5-1.01.0
Locomotion distance, session 80.81.22.61.00.91.2-1.20.1-1.1-1.30.1-0.1-1.61.6
Degree of sensitization distance0.60.61.30.70.60.8-0.8-1.10.0-0.0-0.10.1-1.11.1
Degree of sensitization stereotypy0.60.72.6-0.6-0.5-0.50.51.6-1.1-1.30.2-0.2-0.50.5
Conditioned locomotion1.01.11.7-1.2-1.2-1.11.11.0-1.0-0.9-1.31.3-0.70.7
Cocaine response after cond. corrected0.91.02.51.51.41.6-1.6-1.10.60.60.3-0.3-0.20.2
Cocaine response after cond. not corrected0.70.71.81.31.21.3-1.3-0.70.40.40.2-0.2-0.50.5
Cocaine response before conditioning0.60.71.5-1.2-1.1-1.21.21.2-0.6-0.5-0.30.3-0.10.1
Saline control response3.14.16.1-2.4-2.5-2.32.31.7-1.8-1.6-2.32.3-1.11.1
Bone: connectivity density1.82.85.2-1.4-1.4-1.11.11.7-1.9-2.0-1.41.3-2.32.3
Bone: cortical apparent density0.50.61.2-0.9-0.9-1.11.10.30.10.2-0.50.51.0-1.0
Bone: cortical area0.20.40.6-0.8-0.7-0.70.70.3-0.6-0.8-0.30.3-0.60.6
Bone: cortical porosity0.30.31.9-0.3-0.2-0.30.31.4-0.7-0.7-0.10.10.1-0.1
Bone: cortical porosity0.80.93.7-0.9-0.9-0.90.91.9-1.1-0.9-0.60.6-0.10.1
Bone: cortical thickness2.13.56.6-2.5-2.5-2.62.61.3-1.0-0.8-2.12.10.3-0.3
Bone: cortical thickness0.80.92.1-0.9-1.0-0.90.90.8-0.9-0.7-1.41.5-0.10.1
Bone: cortical tissue density0.60.71.4-1.0-1.1-1.21.20.40.10.2-0.60.61.0-1.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.4-0.4-0.40.4-0.50.40.5-0.40.4-0.00.0
Condit. Reinf. active-inactive response ratio0.40.41.2-0.4-0.4-0.60.6-0.40.91.1-0.10.10.8-0.8
Condit. Reinf. active responses0.10.10.50.10.10.1-0.2-0.70.50.50.1-0.1-0.30.3
Condit. Reinf. inactive responses0.40.51.00.80.80.9-0.9-0.1-0.2-0.50.5-0.6-1.01.0
Incentive salience index mean0.20.20.5-0.3-0.4-0.30.3-0.3-0.1-0.1-0.60.6-0.70.7
Condit. Reinf. lever presses0.20.31.3-0.3-0.3-0.10.10.0-0.5-0.6-0.30.3-1.11.1
Condit. Reinf. active minus inactive responses0.30.41.20.50.60.5-0.50.30.70.61.1-1.1-0.10.1
Condit. Reinf. active-inactive response ratio1.41.43.51.21.41.3-1.3-0.20.90.61.8-1.9-0.50.5
Condit. Reinf. active responses0.00.10.3-0.2-0.1-0.20.20.50.10.10.3-0.3-0.10.1
Condit. Reinf. inactive responses0.50.71.3-1.0-1.0-1.01.00.6-0.5-0.4-1.11.20.1-0.1
Condit. Reinf. lever presses1.11.52.6-1.5-1.3-1.31.31.6-1.2-1.3-0.50.5-1.21.2
Condit. Reinf. lever reinforcers received0.10.20.8-0.6-0.5-0.60.60.9-0.1-0.10.1-0.2-0.10.1
Conditioned reinforcement - actives0.50.51.80.50.60.4-0.40.10.30.31.3-1.40.4-0.4
Conditioned reinforcement - inactives6.27.09.82.52.62.3-2.3-3.13.02.73.1-3.11.9-1.9
Conditioned locomotion9.010.817.43.33.43.1-3.1-4.23.73.43.5-3.42.3-2.3
Patch foraging indifference point 0 sec0.20.30.90.30.30.2-0.2-0.70.90.90.4-0.40.4-0.4
Patch foraging indifference point AUC2.62.95.3-2.3-2.2-2.22.22.0-1.6-1.6-1.21.2-0.50.5
Delay disc. indifference point, 0s delay1.01.02.20.70.61.0-1.00.3-1.3-1.3-0.60.7-1.51.5
Delay disc. indifference point, 16s delay1.21.23.61.11.11.0-1.0-1.91.31.01.0-1.00.5-0.5
Delay disc. indifference point, 2s delay0.30.30.90.40.40.6-0.6-0.3-0.5-0.6-0.00.0-0.90.9
Delay disc. indifference point, 24s delay0.40.31.7-0.0-0.1-0.10.1-1.30.50.5-0.50.60.7-0.7
Delay disc. indifference point, 4s delay0.30.30.80.30.10.4-0.4-0.3-0.5-0.5-0.90.9-0.60.6
Delay disc. indifference point, 8s delay0.30.30.60.1-0.00.2-0.20.3-0.7-0.6-0.80.8-0.60.6
Indifference point function ln k5.37.313.43.73.53.6-3.6-3.32.52.41.8-1.70.7-0.7
Indifference point function log k5.37.313.43.73.53.6-3.6-3.32.52.41.8-1.70.7-0.7
Patch foraging total patch changes 0 sec0.20.30.90.10.10.0-0.0-0.50.90.90.1-0.10.6-0.6
Patch foraging total patch changes 12 sec3.24.16.7-2.6-2.5-2.52.52.3-1.8-1.7-1.91.8-0.70.7
Patch foraging total patch changes 18 sec0.40.61.3-1.1-1.1-1.11.10.9-0.3-0.2-0.40.4-0.10.1
Patch foraging total patch changes 24 sec1.51.83.5-1.9-1.8-1.81.80.5-0.9-1.0-1.41.4-0.10.1
Patch foraging total patch changes 6 sec0.50.71.3-0.9-0.9-0.80.80.1-0.7-0.8-1.11.1-0.80.8
Patch foraging time to switch 0 sec1.32.04.6-0.9-0.9-0.60.61.1-1.9-2.1-0.90.8-2.22.2
Patch foraging water rate 0 sec3.55.610.72.02.01.7-1.7-2.73.33.32.0-1.92.5-2.5
Patch foraging water rate 12 sec5.68.613.03.12.92.7-2.7-3.63.63.62.0-1.92.8-2.8
Patch foraging water rate 18 sec2.12.86.22.11.92.0-1.9-2.51.81.80.9-0.80.9-0.9
Patch foraging water rate 24 sec2.33.24.82.01.91.8-1.8-1.82.22.11.3-1.31.5-1.5
Patch foraging water rate 6 sec2.94.28.22.22.01.9-1.9-2.92.72.71.0-1.01.7-1.7
Seeking ratio, delayed vs. immediate footshock0.20.20.60.40.40.3-0.3-0.80.50.50.2-0.20.4-0.4
Distance traveled before self-admin0.20.20.5-0.7-0.6-0.60.60.7-0.4-0.50.0-0.1-0.30.3
Distance traveled after self-admin0.20.20.7-0.5-0.5-0.60.60.8-0.0-0.00.2-0.20.5-0.5
Extensor digitorum longus weight5.521.630.3-5.0-5.0-4.54.54.4-5.5-5.4-4.84.7-3.43.4
Bone: elastic displacement0.70.82.20.80.70.6-0.6-0.80.81.00.1-0.11.5-1.5
Bone: elastic work0.91.22.8-1.0-1.1-1.01.00.8-1.2-1.0-1.71.70.0-0.0
Bone: endosteal estimation1.63.66.52.22.32.5-2.5-1.4-0.2-0.71.4-1.4-2.22.2
Bone: endosteal perimeter2.04.27.32.42.52.7-2.7-1.20.0-0.52.1-2.1-2.12.1
Epididymis fat weight1.94.38.92.92.93.0-3.0-1.41.00.52.2-2.2-0.30.3
Delta time in closed arm before/after self-admin0.50.51.50.30.10.4-0.4-1.0-0.1-0.1-1.21.2-0.60.6
Delta time in open arm before/after self-admin0.40.40.6-0.6-0.5-0.70.7-0.20.70.60.6-0.60.7-0.7
Diff in mean of infusions in LGA sessions0.60.61.4-1.0-1.0-1.11.11.2-0.00.1-0.40.40.5-0.5
Delay discount exponential model param0.20.20.3-0.1-0.0-0.20.20.40.40.50.5-0.50.5-0.5
Extinction: sum of active levers before priming4.24.18.6-2.2-2.1-2.02.02.9-2.5-2.4-1.61.6-1.21.2
Active lever presses in extinction session 61.91.83.8-1.9-1.8-1.91.91.9-0.9-0.9-0.60.6-0.10.1
Bone: final force2.43.98.4-1.7-1.7-1.51.52.1-2.7-2.9-1.51.5-1.91.9
Bone: final moment2.23.57.9-1.6-1.6-1.41.42.0-2.6-2.8-1.41.4-1.81.8
Food consumed during 24 hour testing period0.30.41.0-0.4-0.3-0.60.6-0.00.60.50.5-0.51.0-1.0
Glucose1.92.85.92.32.32.4-2.4-1.30.70.41.5-1.5-0.90.9
Heart weight2.43.46.42.52.42.5-2.5-2.31.41.31.3-1.30.4-0.4
Delay discount hyperbolic model param0.20.20.4-0.1-0.0-0.30.20.30.50.60.6-0.60.7-0.7
Intermittent access intake day 1-15 change0.80.81.90.30.40.1-0.10.11.01.01.4-1.41.2-1.2
Intermittent access intake escalation0.70.71.60.40.50.2-0.20.01.01.01.3-1.31.0-1.0
Intermittent access intake escalation 20.70.61.3-0.00.1-0.20.2-0.21.11.01.1-1.11.1-1.1
Intermitt. access day 1 inactive lever presses2.02.23.11.71.81.6-1.6-1.41.41.31.8-1.70.8-0.8
Intermitt. access day 15 inactive lever presses3.64.06.12.12.22.0-2.0-2.42.01.62.5-2.50.9-0.9
Intermitt. access escalation Index1.81.63.01.71.61.7-1.7-1.61.11.00.6-0.60.3-0.3
Intermittent access day 1 total infusions5.66.512.93.43.53.6-3.6-2.61.20.82.4-2.4-0.80.8
Intermittent access day 15 total infusions7.07.912.73.53.63.4-3.4-2.22.31.93.5-3.50.6-0.6
Intermittent access terminal intake (last 3 days)5.25.79.93.03.13.1-3.1-1.71.61.13.0-3.1-0.20.2
Intermittent access total infusions4.95.49.53.03.13.1-3.1-1.91.41.02.7-2.8-0.30.3
Intermittent access day 1 locomotion4.14.39.42.92.83.1-3.1-2.20.80.41.4-1.4-1.11.1
Intermittent access day 15 total locomotion4.75.17.42.62.72.6-2.6-2.52.11.72.6-2.60.4-0.4
Intermittent access total locomotion6.87.713.23.53.63.6-3.6-3.11.81.33.0-3.0-0.60.6
Intermittent access standard deviation1.11.22.40.91.00.8-0.8-0.21.21.21.6-1.60.9-0.9
Left kidney weight0.51.52.01.41.41.4-1.4-1.41.21.11.4-1.40.2-0.2
Right kidney weight0.20.61.90.80.90.8-0.8-0.60.40.11.4-1.40.2-0.2
Cocaine induced anxiety0.00.00.1-0.1-0.0-0.00.0-0.30.0-0.00.3-0.4-0.10.1
Post-drug Anxiety0.70.81.7-1.1-1.0-1.11.01.3-1.1-1.1-0.30.2-0.50.5
Baseline Anxiety2.32.56.2-1.6-1.6-1.61.62.5-1.8-1.6-1.51.5-0.50.5
Tail length0.92.75.1-2.2-2.3-2.32.31.2-0.7-0.4-2.02.00.2-0.2
Length with tail1.65.98.4-2.9-2.9-2.82.82.5-2.6-2.4-2.62.6-0.80.8
Length without tail1.32.96.0-1.6-1.6-1.41.42.2-2.4-2.4-1.51.4-1.01.0
Times rat made contact with spout0.60.61.2-1.0-1.1-1.11.10.4-0.10.1-1.01.00.3-0.3
Lifetime Intake4.04.58.92.92.93.0-3.0-1.61.10.82.3-2.3-0.50.5
Liver weight, left0.30.51.40.50.50.6-0.60.7-0.6-0.70.1-0.1-1.21.2
Liver weight, right0.71.12.60.60.50.9-0.90.2-1.4-1.6-0.60.7-1.61.6
Locomotor activity0.91.42.51.41.31.3-1.3-1.11.51.60.6-0.51.0-1.0
Locomotor testing distance1.22.03.21.81.61.6-1.6-1.61.71.70.4-0.31.1-1.1
Locomotor testing rearing1.01.52.81.71.51.6-1.6-1.11.31.30.5-0.50.8-0.8
Locomotion in novel chamber4.35.38.82.62.72.5-2.5-2.12.21.93.0-3.00.8-0.8
Locomotion in novel chamber post-restriction2.32.83.91.92.01.8-1.8-1.51.81.71.9-1.90.7-0.7
Fecal boli incidents, locomotor time 10.20.20.5-0.3-0.2-0.30.30.7-0.2-0.40.7-0.7-0.30.3
Change in fecal boli incidents, locomotor task0.40.41.00.40.20.5-0.5-0.4-0.7-0.5-0.91.0-0.60.6
Time >=10cm from walls, locomotor time 11.41.42.21.21.31.4-1.40.4-0.3-0.61.4-1.5-1.31.3
Bouts of movement, locomotor time 12.32.55.0-1.9-1.8-2.22.21.00.60.8-0.40.42.0-2.0
Total resting periods, locomotor time 11.71.93.7-1.6-1.5-1.91.90.80.70.8-0.10.11.8-1.8
Rest time, locomotor task time 11.61.83.81.01.00.8-0.8-1.81.91.91.3-1.21.3-1.3
Distance moved, locomotor task time 10.90.92.5-0.1-0.10.1-0.11.6-1.4-1.5-0.50.5-1.21.2
Vertical activity count, locomotor time 10.80.92.01.41.31.4-1.4-0.10.30.10.9-0.8-0.30.3
Time >=10cm from walls, locomotor time 20.20.20.5-0.3-0.2-0.40.40.60.20.20.7-0.70.5-0.5
Bouts of movement, locomotor time 20.40.40.9-0.9-0.8-0.90.90.40.00.0-0.40.40.6-0.6
Total resting periods, locomotor time 20.20.20.4-0.5-0.5-0.60.60.20.10.1-0.20.20.5-0.5
Rest time, locomotor task time 21.92.23.81.91.91.9-1.9-1.41.21.21.5-1.40.1-0.1
Distance moved, locomotor task time 21.31.53.8-1.5-1.5-1.51.51.9-1.0-0.8-0.90.90.1-0.1
Vertical activity count, locomotor time 20.20.20.6-0.3-0.4-0.50.50.40.20.5-0.50.50.8-0.8
Light reinforcement 10.30.62.00.10.1-0.00.0-0.81.31.40.4-0.40.9-0.9
Light reinforcement 21.62.25.31.41.61.4-1.4-1.31.31.02.3-2.30.6-0.6
Bone: marrow area1.73.76.72.32.32.6-2.6-1.5-0.2-0.61.3-1.4-2.22.2
Bone: maximum diameter0.10.31.1-0.10.00.0-0.00.0-0.2-0.40.5-0.6-1.01.0
Bone: maximum force2.74.711.4-1.5-1.4-1.11.02.0-3.0-3.4-1.31.2-3.03.0
Bone: maximum moment2.44.110.3-1.3-1.3-1.00.91.8-2.9-3.2-1.21.2-2.82.8
Mean time between licks in bursts0.81.13.3-0.9-1.0-0.80.90.6-1.2-1.0-1.81.8-0.10.1
Mean num. licks in bursts0.10.10.20.10.10.1-0.1-0.10.30.4-0.10.10.5-0.5
Cd content in liver0.91.02.30.81.00.8-0.8-0.51.10.91.5-1.50.8-0.8
Co content in liver1.72.05.50.50.40.2-0.2-1.21.92.30.2-0.12.3-2.3
Cu content in liver0.20.30.5-0.7-0.7-0.70.70.4-0.00.1-0.40.40.5-0.5
Fe content in liver0.20.30.7-0.4-0.3-0.30.30.8-0.7-0.8-0.0-0.0-0.70.7
K content in liver1.61.54.7-0.7-0.8-0.50.50.2-1.2-1.2-1.31.3-2.22.2
Mg content in liver0.50.51.70.40.40.6-0.6-0.9-0.2-0.4-0.20.2-1.31.3
Mn content in liver1.41.63.0-1.6-1.4-1.51.51.7-1.5-1.6-0.60.5-0.50.5
Na content in liver0.40.40.7-0.9-0.8-0.80.80.4-0.6-0.6-0.50.5-0.70.7
Rb content in liver1.11.43.01.71.71.7-1.7-1.10.60.41.0-0.9-0.30.3
Se content in liver0.40.51.70.00.2-0.0-0.0-0.41.00.71.3-1.30.1-0.1
Sr content in liver2.32.14.6-2.1-2.0-2.12.11.2-0.7-0.7-1.11.10.4-0.4
Zn content in liver0.40.51.0-1.0-1.0-1.01.00.1-0.4-0.5-0.70.7-0.20.2
Bone: minimum diameter1.52.85.02.02.02.2-2.2-1.90.2-0.31.3-1.3-1.81.8
Time in familiar zone, hab. session 10.30.20.80.60.60.6-0.6-0.90.10.00.3-0.3-0.20.2
Time in novel zone, hab. session 10.10.10.10.30.20.3-0.30.10.10.2-0.20.30.1-0.1
Total zone transitions, hab. session 10.40.61.1-0.8-0.7-0.70.71.0-1.0-1.0-0.60.6-0.40.4
Total locomotion distance, hab. session 10.50.81.51.11.11.2-1.2-0.8-0.0-0.20.6-0.6-0.80.8
Locomotion velocity, hab. session 10.10.20.40.50.50.6-0.6-0.5-0.2-0.30.2-0.2-0.60.6
Time in familiar zone, hab. session 20.30.31.2-0.3-0.5-0.40.40.4-0.20.0-1.11.10.1-0.1
Time in novel zone, hab. session 20.10.10.20.10.20.2-0.2-0.5-0.1-0.30.4-0.4-0.20.2
Total zone transitions, hab. session 21.41.83.8-0.7-0.7-0.40.41.0-1.9-1.9-1.31.3-1.91.9
Total locomotion distance, hab. session 20.60.82.30.70.60.9-0.9-0.6-0.7-0.8-0.30.3-1.51.5
Locomotion velocity, hab. session 20.70.92.20.90.91.1-1.1-0.7-0.5-0.70.1-0.1-1.51.5
Novel to familiar place preference ratio0.60.61.1-1.1-0.9-1.01.01.1-0.6-0.8-0.0-0.1-0.50.5
Novelty place preference0.30.30.5-0.7-0.6-0.70.70.7-0.3-0.50.3-0.3-0.20.2
Time in novel zone, NPP test0.20.20.4-0.6-0.5-0.50.50.6-0.3-0.50.2-0.2-0.30.3
Total zone transitions, NPP test2.23.26.2-1.5-1.5-1.21.22.4-2.5-2.4-1.51.4-1.61.6
Total locomotion distance, NPP test0.50.61.80.40.30.6-0.60.3-1.0-1.1-0.30.3-1.31.3
Locomotion velocity, NPP test0.30.40.90.20.20.3-0.30.4-0.9-0.9-0.20.2-1.01.0
Intraocular pressure2.02.85.90.40.60.1-0.1-0.92.42.31.9-1.92.3-2.3
Delta distance traveled before/after self-admin0.00.00.10.1-0.00.0-0.00.4-0.00.1-0.30.30.3-0.3
Delta ambulatory time before/after self-admin0.10.10.3-0.0-0.1-0.00.00.6-0.3-0.2-0.50.50.1-0.1
Parametrial fat weight1.83.57.22.52.52.7-2.7-1.71.10.81.6-1.6-1.11.1
Pavlov. Cond. lever latency0.30.41.20.40.40.3-0.3-0.10.91.10.5-0.40.9-0.9
Pavlov. Cond. magazine entry latency0.20.20.8-0.3-0.2-0.20.2-0.1-0.4-0.5-0.20.2-0.90.9
Pavlov. Cond. change in total contacts0.10.10.5-0.10.0-0.10.1-0.30.20.00.7-0.7-0.10.1
Pavlov. Cond. index score0.10.10.3-0.5-0.5-0.50.50.2-0.3-0.4-0.10.1-0.10.1
Pavlov. Cond. latency score0.10.10.3-0.3-0.3-0.30.30.0-0.4-0.5-0.20.2-0.40.4
Pavlov. Cond. lever contacts0.10.20.6-0.0-0.10.0-0.0-0.1-0.7-0.8-0.30.3-0.50.5
Pavlov. Cond. magazine entry number0.20.30.70.80.70.9-0.9-0.5-0.2-0.1-0.10.1-0.30.3
Pavlov. Cond. intertrial magazine entries1.11.43.10.40.50.2-0.2-0.71.61.51.2-1.21.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.30.30.5-0.7-0.7-0.70.70.5-0.6-0.7-0.30.3-0.30.3
Pavlov. Cond. response bias0.10.10.2-0.4-0.4-0.50.5-0.00.1-0.00.1-0.10.1-0.1
Pavlov. Cond. lever latency0.40.51.10.50.50.4-0.4-0.80.81.10.0-0.01.0-1.0
Pavlov. Cond. magazine entry latency2.73.14.7-2.2-2.1-2.12.02.1-1.7-1.7-1.61.5-0.90.9
Pavlov. Cond. change in total contacts1.01.43.9-1.3-1.1-1.31.22.0-1.4-1.70.1-0.2-0.60.6
Pavlov. Cond. index score1.51.93.4-1.6-1.5-1.51.51.9-1.5-1.7-0.70.6-1.01.0
Pavlov. Cond. latency score1.31.62.8-1.4-1.3-1.21.21.7-1.4-1.6-0.60.5-1.21.2
Pavlov. Cond. lever contacts0.30.41.0-0.8-0.7-0.80.81.0-0.4-0.5-0.0-0.0-0.30.3
Pavlov. Cond. magazine entry number4.25.17.82.82.72.6-2.6-2.72.42.51.7-1.61.1-1.1
Pavlov. Cond. intertrial magazine entries0.60.81.31.01.00.9-0.9-0.51.11.11.0-1.00.4-0.4
Pavlov. Cond. lever-magazine prob. diff.1.92.44.1-1.9-1.8-1.71.72.0-1.7-1.8-0.90.8-1.01.0
Pavlov. Cond. response bias1.11.53.1-1.6-1.5-1.51.51.8-1.2-1.3-0.60.6-0.60.6
Time in closed arm before self-admin0.10.10.3-0.2-0.1-0.20.20.6-0.5-0.50.4-0.4-0.30.3
Time in closed arm after self-admin0.20.20.40.60.50.6-0.6-0.5-0.2-0.2-0.20.2-0.30.3
Time in open arm before self-admin0.30.30.70.60.40.6-0.6-0.60.40.6-0.80.80.2-0.2
Time in open arm after self-admin0.50.51.4-0.3-0.3-0.40.4-0.31.01.20.0-0.01.2-1.2
Bone: periosteal estimation0.61.33.50.90.91.1-1.1-0.7-0.5-0.90.8-0.8-1.91.9
Bone: periosteal perimeter0.30.61.90.20.30.4-0.40.2-0.7-1.00.4-0.5-1.41.4
Bone: post-yield work2.33.110.30.80.91.2-1.20.3-1.6-2.10.9-1.0-3.23.2
Progressive ratio test 1 active lever presses2.72.84.22.02.01.9-1.9-1.41.51.42.0-2.00.8-0.8
Progressive ratio test 1 breakpoint2.32.43.61.81.91.7-1.7-1.21.41.31.9-1.90.8-0.8
Progressive ratio test 1 inactive lever presses0.91.01.61.31.21.2-1.2-1.10.90.80.8-0.80.6-0.6
Progressive ratio test 2 active lever presses4.75.17.82.62.72.5-2.5-2.32.11.82.8-2.80.7-0.7
Progressive ratio test 2 breakpoint5.86.59.42.82.92.6-2.6-2.62.62.43.1-3.01.4-1.4
Progressive ratio test 2 inactive lever presses8.09.313.23.53.63.3-3.3-3.13.02.63.6-3.61.3-1.3
Incentive Sensitization - Responses0.90.91.60.91.00.9-0.9-1.21.00.81.3-1.30.2-0.2
Incentive Sensitization - Breakpoint1.31.32.21.11.21.1-1.1-1.51.21.01.5-1.50.3-0.3
Sum of active levers in priming session hrs 5-61.31.32.9-1.6-1.3-1.71.71.30.10.00.5-0.51.0-1.0
Progressive ratio3.03.47.1-1.2-1.2-1.00.92.7-2.6-2.6-1.11.1-2.22.2
Food seeking constrained by brief footshock0.30.31.1-0.4-0.5-0.40.40.3-0.5-0.4-1.01.1-0.40.4
Seeking ratio, punishment vs. effort2.12.57.21.21.00.9-0.9-2.72.22.30.4-0.31.7-1.7
Retroperitoneal fat weight4.314.023.74.94.94.8-4.8-3.73.12.73.8-3.80.4-0.4
Reaction time number correct0.50.72.5-0.8-0.8-0.80.81.6-0.9-0.9-0.60.60.2-0.2
Reaction time mean minus median2.53.37.9-2.0-1.9-1.91.92.8-2.2-2.3-0.80.7-1.21.2
Reaction time mean minus median AUC1.52.05.4-1.7-1.6-1.71.72.3-1.4-1.4-0.70.7-0.50.5
Reaction time num false alarms0.10.20.40.50.30.4-0.4-0.30.10.4-0.50.60.6-0.6
Reaction time num false alarms AUC0.20.31.3-0.2-0.4-0.30.30.5-0.5-0.2-1.11.10.3-0.3
Reaction time trials correct on left0.50.72.5-0.8-0.8-0.80.81.6-0.9-0.9-0.60.60.2-0.2
Reaction time trials on left0.60.93.0-0.9-0.9-0.90.91.7-1.0-1.0-0.70.70.2-0.2
Reaction time mean0.10.10.5-0.2-0.1-0.20.20.7-0.1-0.20.6-0.70.0-0.0
Reaction time mean AUC0.10.10.6-0.10.0-0.10.10.7-0.1-0.20.7-0.80.0-0.0
Median of all reaction times0.20.20.80.40.40.4-0.4-0.10.40.30.9-0.90.1-0.1
Reaction time omissions1.01.45.3-1.3-1.2-1.31.32.3-1.2-1.0-0.70.70.0-0.0
Reaction time false alarm rate0.10.20.50.50.40.5-0.5-0.70.20.4-0.50.50.1-0.1
Reaction time premature initiation rate2.12.86.9-1.7-1.9-1.61.60.5-1.5-1.3-2.62.6-0.80.8
Reaction time premature initiations3.34.68.6-2.5-2.6-2.42.41.5-2.0-1.7-2.92.9-0.40.4
Std. dev. reaction times0.60.93.0-1.1-1.0-1.11.11.7-0.9-0.90.0-0.0-0.10.1
Reaction time trials completed0.60.93.0-0.9-0.9-0.90.91.7-1.0-1.0-0.70.70.2-0.2
Reaction time trials AUC0.40.62.4-0.7-0.7-0.70.71.5-0.9-0.9-0.60.60.2-0.2
Run reversals in cocaine runway, females1.31.32.90.0-0.20.3-0.3-0.3-1.2-1.2-1.61.6-1.71.7
Run reversals in cocaine runway, males0.00.00.10.20.20.2-0.20.20.00.10.1-0.10.1-0.1
Latency to leave start box in cocaine runway0.40.40.80.70.70.8-0.8-0.9-0.1-0.20.4-0.4-0.90.9
Latency to leave start box in cocaine runway, F0.10.10.40.10.10.1-0.1-0.60.20.10.2-0.2-0.30.3
Latency to leave start box in cocaine runway, M0.40.40.80.60.60.7-0.70.2-0.7-0.70.2-0.2-0.90.9
Std. dev. time between licks in bursts0.20.20.80.20.00.2-0.2-0.2-0.5-0.5-0.80.90.3-0.3
Total sessions with >9 infusions2.02.25.22.12.12.3-2.3-1.00.30.11.0-1.0-0.80.8
Short access day 1 total inactive lever presses4.14.67.22.72.72.6-2.6-2.62.01.81.9-1.90.8-0.8
Short access day 10 total inactive lever presses2.62.94.42.12.01.9-1.9-2.11.81.81.2-1.11.2-1.2
Short access day 1 total infusions2.72.96.22.42.42.5-2.5-1.40.90.61.5-1.5-0.40.4
Short access day 10 total infusions2.62.96.32.32.32.5-2.5-1.10.2-0.11.3-1.3-1.51.5
Short access total infusions1.82.14.92.02.02.2-2.2-0.80.1-0.11.0-1.0-1.11.1
Short access day 1 locomotion2.32.45.52.22.22.4-2.4-1.50.70.31.0-1.0-0.70.7
Short access day 10 total locomotion1.82.03.91.91.81.9-1.9-2.01.00.71.0-1.0-0.50.5
Short access total locomotion2.12.14.31.91.92.1-2.1-2.10.80.40.8-0.8-0.80.8
One hour access (0.3 mA shock)8.910.414.73.83.83.6-3.6-3.43.12.83.6-3.61.4-1.4
Compulsive drug intake2.93.06.0-2.0-2.2-2.12.11.0-1.0-0.7-2.42.40.4-0.4
One hour access (shock baseline)8.59.817.63.53.73.4-3.4-2.52.82.54.2-4.21.2-1.2
Social response proportion0.60.71.1-1.0-1.0-1.01.00.9-0.8-0.6-0.60.6-0.60.6
Social responses0.50.61.3-1.1-1.1-1.11.11.1-0.3-0.0-0.70.70.1-0.1
Social time0.40.61.1-0.9-0.9-0.90.91.1-0.5-0.3-0.80.8-0.10.1
Soleus weight2.88.212.63.63.53.4-3.4-3.12.72.62.7-2.71.2-1.2
Bone: stiffness1.82.85.4-1.5-1.4-1.21.21.9-2.2-2.3-0.90.8-2.22.2
Tibialis anterior weight7.425.437.4-6.1-6.1-5.85.85.3-5.1-4.8-5.04.9-2.52.5
Time to tail flick, vehicle, before self-admin1.21.33.4-0.3-0.3-0.00.00.8-1.6-1.8-0.50.5-1.91.9
Time to tail flick, vehicle, after self-admin3.53.76.4-1.2-1.3-0.90.91.7-2.5-2.5-2.22.2-2.32.3
Time to tail flick, test, before self-admin1.11.02.51.41.31.6-1.6-0.8-0.3-0.50.0-0.0-1.01.0
Time to tail flick, test, after self-admin0.20.20.7-0.3-0.3-0.30.30.8-0.4-0.4-0.30.3-0.30.3
Delta time to tail flick, vehicle, before/after SA1.01.01.7-0.8-0.9-0.70.71.0-1.1-1.0-1.31.3-0.90.9
Delta time to tail flick, test, before/after SA1.81.63.8-1.8-1.7-2.02.01.20.10.3-0.40.41.1-1.1
Tibia length0.51.32.6-1.6-1.4-1.61.51.3-1.0-1.30.1-0.2-0.40.4
Ambulatory time before self-admin0.20.20.5-0.6-0.4-0.60.60.7-0.1-0.20.5-0.50.0-0.0
Ambulatory time after self-admin0.30.31.00.40.50.4-0.4-0.40.60.51.0-1.00.3-0.3
Bone: tissue strength0.10.10.2-0.1-0.0-0.10.10.30.30.30.5-0.50.3-0.3
Total heroin consumption4.85.610.2-2.9-2.9-2.82.83.2-2.2-2.0-2.12.1-0.60.6
Bone: trabecular number0.60.92.3-0.3-0.3-0.10.11.1-1.2-1.5-0.0-0.0-1.51.5
Bone: trabecular spacing0.40.61.70.20.10.00.0-0.91.01.3-0.20.31.1-1.1
Bone: trabecular thickness0.60.71.31.11.11.1-1.10.20.1-0.11.0-1.0-0.40.4
Bone: trabecular tissue density2.13.04.21.81.91.6-1.6-1.12.02.02.1-2.01.4-1.4
Water consumed over 24 hours0.91.12.2-1.4-1.4-1.51.50.6-0.4-0.2-0.90.90.9-0.9
Number of responses in last shaping day1.01.01.61.11.01.0-1.0-1.11.31.20.6-0.51.0-1.0