Hub : Genes

LOC102557269

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability LOC102557269 0.43 0.15 2.3e-14 0.27 0.26 0.25 0.27 7.1e-15 5.5e-14 1.7e-13 8.0e-15
2 NAcc mRNA stability LOC102557269 0.25 0.24 3.6e-11 0.11 0.1 0.11 0.11 2.5e-12 4.8e-12 2.7e-12 1.9e-12
3 BLA gene expression LOC102557269 0.26 0.14 2.8e-07 0.13 0.12 0.13 0.12 1.6e-07 5.7e-07 2.6e-07 3.6e-07
4 NAcc gene expression LOC102557269 0.21 0.06 0.0e+00 0.25 0.24 0.25 0.25 9.4e-29 5.9e-28 1.3e-28 2.8e-28
5 pVTA gene expression LOC102557269 0.23 0.13 2.6e-06 0.12 0.11 0.12 0.11 5.7e-06 2.1e-05 8.7e-06 1.5e-05
6 Brain gene expression LOC102557269 0.49 0.24 2.5e-15 0.14 0.14 0.13 0.14 2.1e-13 7.0e-13 3.0e-12 1.3e-12
7 IL gene expression LOC102557269 0.24 0.15 6.8e-03 0.05 0.04 0.04 0.05 2.3e-02 4.6e-02 4.2e-02 2.9e-02
8 PL mRNA stability LOC102557269 0.14 0.07 2.3e-11 0.09 0.11 0.1 0.1 8.5e-10 1.0e-11 4.8e-11 5.8e-11
9 Brain mRNA stability LOC102557269 0.33 0.14 0.0e+00 0.22 0.21 0.2 0.22 4.0e-20 2.9e-19 1.5e-18 6.3e-20
10 Adipose gene expression LOC102557269 0.28 0.14 0.0e+00 0.14 0.14 0.13 0.14 1.3e-15 2.7e-15 1.5e-14 1.4e-15
11 PL gene expression LOC102557269 0.19 0.08 0.0e+00 0.15 0.18 0.17 0.17 1.7e-16 6.6e-19 5.6e-18 1.2e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.01.11.0-1.11.11.11.11.01.0-0.90.90.9-0.7
Area under the delay curve0.20.20.40.4-0.40.50.50.60.5-0.0-0.30.40.3-0.4
BMI with tail3.09.812.73.1-3.13.13.13.03.03.4-3.42.92.5-3.6
BMI without tail2.14.37.21.9-2.02.02.02.02.02.7-2.21.91.9-2.0
Body weight7.631.733.55.8-5.85.75.75.85.75.4-5.75.65.2-5.6
Weight adjusted by age1.82.03.41.0-1.01.11.11.31.71.8-1.41.71.8-1.3
Bone surface1.22.23.31.5-1.51.51.51.51.51.8-1.41.41.3-1.1
Bone volume0.60.91.21.0-1.11.11.11.11.01.1-0.80.90.8-0.6
Breakpoint value in progressive ratio session0.10.10.20.3-0.30.30.30.3-0.30.00.1-0.4-0.40.3
Number of licking bursts0.10.10.1-0.30.2-0.2-0.2-0.2-0.2-0.30.3-0.20.20.3
Context. condit. distance diff. score0.60.70.9-0.80.8-0.8-0.8-0.8-1.0-0.80.8-1.0-0.90.7
Locomotion velocity, session 10.20.20.3-0.50.5-0.5-0.5-0.5-0.5-0.30.4-0.5-0.20.3
Locomotion distance, session 12.63.34.1-1.81.8-1.8-1.8-1.8-1.8-2.02.0-1.8-1.71.8
Locomotion velocity, session 20.30.30.60.6-0.60.60.60.60.50.0-0.50.50.8-0.6
Locomotion distance, session 23.85.47.0-2.32.3-2.3-2.3-2.3-2.3-2.62.4-2.3-2.32.0
Locomotion velocity, session 31.61.82.6-1.31.3-1.3-1.3-1.3-1.4-1.61.3-1.4-1.41.1
Locomotion distance, session 31.31.52.7-1.11.1-1.1-1.1-1.1-1.2-1.61.2-1.3-1.50.8
Stereotopy head waving bouts, day 30.50.60.90.7-0.70.70.70.70.81.0-0.70.80.7-0.5
Stereotopy head waving duration, day 31.51.82.71.2-1.21.21.21.31.41.7-1.41.41.4-1.3
Locomotion velocity, session 70.10.10.2-0.40.3-0.3-0.3-0.3-0.4-0.40.3-0.3-0.30.0
Locomotion distance, session 70.50.71.3-0.90.8-0.8-0.8-0.8-0.8-1.10.9-0.8-0.90.6
Stereotopy head waving bouts, day 70.81.01.71.0-1.01.01.01.00.90.8-1.10.90.8-1.3
Stereotopy head waving duration, day 72.32.83.61.7-1.71.71.71.71.61.6-1.81.61.4-1.9
Locomotion velocity, session 82.63.14.7-1.71.7-1.7-1.7-1.7-1.9-2.21.7-2.0-1.81.3
Locomotion distance, session 84.56.68.7-2.52.5-2.5-2.5-2.5-2.6-3.02.6-2.6-2.62.3
Degree of sensitization distance0.50.50.80.5-0.60.60.60.70.80.7-0.70.80.9-0.7
Degree of sensitization stereotypy0.60.71.60.9-0.80.80.80.80.70.7-1.00.70.5-1.3
Conditioned locomotion0.10.10.10.4-0.40.40.40.40.20.2-0.20.30.3-0.1
Cocaine response after cond. corrected0.80.91.10.9-1.01.01.01.00.91.1-0.90.90.9-0.9
Cocaine response after cond. not corrected0.60.70.90.8-0.90.90.90.90.90.7-0.80.91.0-0.7
Cocaine response before conditioning0.10.10.20.3-0.20.20.20.20.4-0.1-0.10.40.4-0.2
Saline control response1.62.12.41.5-1.61.61.61.61.51.2-1.31.51.4-1.2
Bone: connectivity density0.91.41.61.2-1.31.31.31.31.21.3-1.21.11.1-1.0
Bone: cortical apparent density0.20.30.4-0.60.6-0.6-0.6-0.6-0.60.10.5-0.5-0.40.6
Bone: cortical area4.16.27.42.4-2.52.52.52.52.52.7-2.52.42.7-2.3
Bone: cortical porosity0.10.10.10.3-0.30.30.30.30.3-0.0-0.00.20.30.1
Bone: cortical porosity0.80.91.11.0-1.01.01.01.01.00.8-0.80.91.0-0.7
Bone: cortical thickness1.42.33.51.5-1.51.51.51.51.61.7-1.41.51.9-1.3
Bone: cortical thickness0.50.61.10.7-0.70.70.70.70.71.0-0.90.81.0-0.9
Bone: cortical tissue density0.20.20.3-0.50.6-0.6-0.6-0.6-0.50.10.5-0.5-0.30.6
Condit. Reinf. active minus inactive responses2.32.62.7-1.61.6-1.6-1.6-1.7-1.6-1.61.6-1.6-1.51.5
Condit. Reinf. active-inactive response ratio0.70.70.8-0.90.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.70.8
Condit. Reinf. active responses1.41.71.9-1.41.4-1.4-1.4-1.4-1.3-1.11.3-1.3-1.31.1
Condit. Reinf. inactive responses0.80.91.1-1.01.0-1.0-1.0-1.0-1.0-0.50.9-1.0-1.00.8
Incentive salience index mean0.60.70.8-0.90.9-0.9-0.9-0.9-0.9-0.80.9-0.9-0.80.7
Condit. Reinf. lever presses0.10.10.20.3-0.30.30.30.20.20.3-0.30.20.4-0.4
Condit. Reinf. active minus inactive responses2.63.33.81.9-1.91.91.91.91.90.7-1.61.91.9-1.8
Condit. Reinf. active-inactive response ratio1.11.11.71.1-1.01.01.01.01.00.3-1.01.11.3-1.3
Condit. Reinf. active responses2.94.04.82.2-2.22.22.22.22.21.0-1.72.22.0-1.8
Condit. Reinf. inactive responses1.51.92.51.6-1.61.61.61.61.50.6-1.11.51.1-1.0
Condit. Reinf. lever presses2.83.85.21.9-1.91.91.91.92.11.5-1.82.12.3-1.9
Condit. Reinf. lever reinforcers received3.34.75.42.3-2.32.32.32.32.31.3-1.92.32.3-1.9
Conditioned reinforcement - actives0.20.20.30.4-0.20.20.20.30.50.3-0.50.40.5-0.6
Conditioned reinforcement - inactives0.80.91.61.0-0.90.90.90.91.3-0.3-0.81.21.1-0.9
Conditioned locomotion0.10.10.30.1-0.20.20.2-0.1-0.00.6-0.30.10.2-0.3
Patch foraging indifference point 0 sec0.20.30.50.6-0.70.70.70.60.40.5-0.50.40.3-0.4
Patch foraging indifference point AUC1.21.42.71.0-1.11.11.11.01.11.7-1.21.11.3-1.1
Delay disc. indifference point, 0s delay0.10.10.2-0.30.2-0.2-0.2-0.4-0.2-0.50.2-0.1-0.10.1
Delay disc. indifference point, 16s delay1.31.32.11.2-1.41.41.41.51.10.4-0.91.00.9-1.0
Delay disc. indifference point, 2s delay0.00.00.10.1-0.10.10.10.20.30.4-0.20.20.2-0.2
Delay disc. indifference point, 24s delay0.50.51.00.8-0.80.80.81.00.70.2-0.60.70.6-0.7
Delay disc. indifference point, 4s delay0.10.10.5-0.20.1-0.1-0.10.0-0.3-0.70.3-0.3-0.30.3
Delay disc. indifference point, 8s delay0.00.00.10.1-0.10.10.10.30.1-0.30.00.0-0.1-0.0
Indifference point function ln k0.40.51.2-0.60.7-0.7-0.7-0.6-0.7-1.10.7-0.6-0.50.6
Indifference point function log k0.40.51.2-0.60.7-0.7-0.7-0.6-0.7-1.10.7-0.6-0.50.6
Patch foraging total patch changes 0 sec0.20.40.60.7-0.80.70.70.70.50.4-0.60.60.4-0.6
Patch foraging total patch changes 12 sec1.92.43.01.5-1.61.61.61.51.51.5-1.71.51.4-1.7
Patch foraging total patch changes 18 sec0.40.51.10.6-0.60.60.60.60.71.0-0.70.70.8-0.6
Patch foraging total patch changes 24 sec1.11.32.31.0-1.11.11.11.01.11.5-1.21.11.1-1.0
Patch foraging total patch changes 6 sec0.71.01.41.1-1.21.11.11.11.00.8-1.01.00.9-0.9
Patch foraging time to switch 0 sec1.62.43.2-1.41.5-1.6-1.6-1.4-1.6-1.81.6-1.6-1.51.6
Patch foraging water rate 0 sec2.23.53.91.9-1.92.02.01.91.91.6-1.91.81.9-1.8
Patch foraging water rate 12 sec1.72.63.51.7-1.61.61.61.71.90.8-1.41.81.8-1.5
Patch foraging water rate 18 sec1.92.53.41.7-1.71.71.71.81.60.9-1.61.51.4-1.8
Patch foraging water rate 24 sec0.30.51.00.7-0.60.60.60.80.70.3-0.70.70.6-1.0
Patch foraging water rate 6 sec1.52.13.01.3-1.31.41.41.41.71.3-1.41.71.6-1.5
Seeking ratio, delayed vs. immediate footshock0.00.00.10.2-0.30.20.20.20.3-0.0-0.10.40.1-0.0
Distance traveled before self-admin0.10.10.2-0.50.5-0.5-0.5-0.4-0.20.10.0-0.2-0.0-0.1
Distance traveled after self-admin0.10.10.30.1-0.10.10.10.00.5-0.1-0.20.40.6-0.4
Extensor digitorum longus weight5.521.722.34.7-4.74.74.74.74.74.6-4.64.74.6-4.5
Bone: elastic displacement0.20.20.4-0.40.5-0.5-0.5-0.5-0.5-0.40.5-0.4-0.30.6
Bone: elastic work1.11.42.11.2-1.21.21.21.21.21.4-1.11.31.1-0.9
Bone: endosteal estimation3.98.410.22.9-2.92.92.92.92.83.2-3.02.82.8-2.9
Bone: endosteal perimeter1.63.25.71.7-1.71.71.71.71.72.4-1.91.71.6-1.7
Epididymis fat weight0.51.11.8-1.01.0-1.0-1.0-1.1-1.2-0.31.0-1.2-1.31.3
Delta time in closed arm before/after self-admin0.80.81.2-1.01.0-1.0-1.0-1.1-0.7-0.40.8-0.8-0.80.9
Delta time in open arm before/after self-admin0.90.91.61.2-1.21.21.21.00.70.2-0.80.70.6-1.0
Diff in mean of infusions in LGA sessions0.50.61.4-0.40.4-0.4-0.4-0.5-1.2-0.70.9-1.1-1.00.9
Delay discount exponential model param0.10.10.3-0.20.3-0.3-0.3-0.5-0.30.10.2-0.2-0.10.2
Extinction: sum of active levers before priming0.10.10.7-0.00.0-0.0-0.0-0.1-0.1-0.80.3-0.2-0.20.1
Active lever presses in extinction session 60.20.20.9-0.10.1-0.1-0.1-0.2-0.5-1.00.6-0.4-0.30.6
Bone: final force1.82.94.51.6-1.71.61.61.61.62.1-1.81.61.7-1.6
Bone: final moment2.74.45.92.0-2.12.12.12.12.12.4-2.22.02.2-1.9
Food consumed during 24 hour testing period2.93.54.41.9-1.91.91.91.91.91.4-1.81.92.1-1.7
Glucose0.00.00.0-0.00.0-0.0-0.0-0.0-0.10.1-0.0-0.1-0.00.0
Heart weight1.92.63.41.8-1.81.71.71.71.61.2-1.51.61.5-1.5
Delay discount hyperbolic model param0.00.00.2-0.20.2-0.2-0.2-0.4-0.30.10.1-0.2-0.10.2
Intermittent access intake day 1-15 change1.71.65.3-1.11.1-1.1-1.1-1.1-1.2-2.31.4-1.1-1.01.2
Intermittent access intake escalation1.21.24.4-0.90.9-0.8-0.8-0.9-1.0-2.11.2-0.9-0.81.0
Intermittent access intake escalation 20.40.42.0-0.50.4-0.4-0.4-0.5-0.7-1.40.7-0.5-0.30.5
Intermitt. access day 1 inactive lever presses0.20.20.3-0.50.5-0.6-0.6-0.6-0.5-0.40.4-0.5-0.40.4
Intermitt. access day 15 inactive lever presses0.30.33.10.0-0.10.00.00.00.1-1.80.50.10.20.4
Intermitt. access escalation Index0.50.50.8-0.70.6-0.5-0.5-0.7-0.9-0.00.6-0.9-0.90.7
Intermittent access day 1 total infusions2.22.62.91.7-1.61.61.61.61.71.4-1.61.71.6-1.5
Intermittent access day 15 total infusions0.30.40.50.7-0.60.70.70.60.6-0.0-0.50.70.6-0.6
Intermittent access terminal intake (last 3 days)0.30.30.60.7-0.60.70.70.60.5-0.3-0.40.60.8-0.4
Intermittent access total infusions2.73.03.51.9-1.81.81.81.81.81.0-1.61.81.7-1.7
Intermittent access day 1 locomotion0.00.00.1-0.10.1-0.1-0.1-0.2-0.10.3-0.0-0.1-0.10.2
Intermittent access day 15 total locomotion0.00.00.1-0.10.0-0.0-0.0-0.20.1-0.10.10.00.00.2
Intermittent access total locomotion0.10.10.20.2-0.30.40.40.20.20.4-0.30.30.3-0.2
Intermittent access standard deviation0.30.32.50.3-0.30.30.30.40.2-1.60.20.0-0.1-0.1
Left kidney weight4.211.913.23.6-3.63.63.63.63.33.4-3.53.23.0-3.4
Right kidney weight4.512.514.43.8-3.83.83.83.73.43.2-3.63.33.1-3.5
Cocaine induced anxiety1.11.21.6-1.11.1-1.1-1.1-1.2-1.3-0.70.9-1.2-1.31.0
Post-drug Anxiety0.50.60.8-0.90.9-0.9-0.9-0.8-0.8-0.10.5-0.7-0.70.6
Baseline Anxiety0.40.51.00.5-0.50.50.50.80.90.2-0.50.91.0-0.6
Tail length0.92.84.01.7-1.71.61.61.81.81.7-1.51.82.0-1.2
Length with tail3.312.013.43.6-3.63.53.53.73.73.1-3.33.63.5-3.0
Length without tail3.27.18.52.9-2.82.82.82.92.81.9-2.62.72.3-2.7
Times rat made contact with spout0.10.20.30.5-0.40.40.40.40.40.2-0.20.40.6-0.2
Lifetime Intake2.93.34.02.0-1.91.91.91.91.91.0-1.71.91.9-1.8
Liver weight, left0.00.10.50.1-0.10.10.10.00.00.10.3-0.10.20.7
Liver weight, right0.20.30.50.7-0.70.70.70.70.70.1-0.20.50.3-0.1
Locomotor activity1.11.82.1-1.41.3-1.2-1.2-1.4-1.4-1.41.3-1.3-1.41.3
Locomotor testing distance0.81.31.9-1.31.2-1.1-1.1-1.4-1.1-0.91.1-1.1-1.11.1
Locomotor testing rearing0.91.42.0-1.21.2-1.1-1.1-1.4-1.2-1.11.2-1.2-1.31.1
Locomotion in novel chamber0.10.10.9-0.20.2-0.2-0.2-0.4-0.21.0-0.1-0.10.10.0
Locomotion in novel chamber post-restriction1.51.82.4-1.51.5-1.6-1.6-1.2-1.2-1.01.3-1.3-1.21.4
Fecal boli incidents, locomotor time 10.00.10.1-0.30.3-0.3-0.3-0.1-0.00.10.2-0.10.10.3
Change in fecal boli incidents, locomotor task0.10.10.2-0.1-0.00.00.0-0.2-0.3-0.30.2-0.3-0.40.3
Time >=10cm from walls, locomotor time 11.21.22.41.1-0.90.90.91.21.40.1-0.81.41.6-0.9
Bouts of movement, locomotor time 10.50.50.9-0.70.8-0.8-0.8-0.5-0.7-0.60.7-0.7-0.90.7
Total resting periods, locomotor time 10.20.20.4-0.40.5-0.5-0.5-0.2-0.5-0.30.5-0.4-0.70.6
Rest time, locomotor task time 10.50.51.1-0.60.6-0.6-0.6-0.5-0.7-0.80.8-0.7-1.10.8
Distance moved, locomotor task time 10.10.20.5-0.40.3-0.3-0.3-0.7-0.40.6-0.1-0.4-0.1-0.1
Vertical activity count, locomotor time 10.20.20.5-0.40.2-0.2-0.2-0.6-0.70.10.1-0.7-0.40.1
Time >=10cm from walls, locomotor time 23.03.24.11.8-1.71.71.71.92.01.4-1.72.02.0-1.7
Bouts of movement, locomotor time 20.30.30.80.6-0.40.40.40.90.60.1-0.40.60.6-0.4
Total resting periods, locomotor time 20.10.10.50.4-0.20.20.20.70.4-0.0-0.20.40.3-0.2
Rest time, locomotor task time 20.91.01.4-1.01.0-0.9-0.9-0.7-1.1-1.01.1-1.1-1.21.1
Distance moved, locomotor task time 20.20.20.8-0.50.5-0.5-0.5-0.9-0.40.10.1-0.5-0.3-0.0
Vertical activity count, locomotor time 20.30.40.80.5-0.60.60.60.20.40.8-0.80.40.5-0.9
Light reinforcement 11.63.04.21.5-1.61.71.71.61.52.1-1.91.51.6-2.0
Light reinforcement 22.83.74.31.9-2.01.91.92.01.72.0-2.01.81.9-2.1
Bone: marrow area3.98.410.32.9-2.92.92.92.92.83.2-3.02.82.8-2.9
Bone: maximum diameter3.36.27.52.5-2.52.52.52.52.52.7-2.52.42.5-2.2
Bone: maximum force2.95.06.52.2-2.22.22.22.22.22.5-2.32.22.0-2.2
Bone: maximum moment3.66.37.32.5-2.52.52.52.52.52.7-2.62.52.4-2.4
Mean time between licks in bursts0.20.30.90.5-0.40.40.40.40.50.6-0.60.50.9-0.5
Mean num. licks in bursts0.30.30.50.7-0.60.70.70.70.60.3-0.50.60.3-0.5
Cd content in liver0.30.30.90.4-0.40.40.40.40.41.0-0.60.30.6-0.6
Co content in liver0.50.50.80.7-0.70.70.70.70.70.9-0.70.80.8-0.6
Cu content in liver0.60.71.0-0.80.9-0.9-0.9-0.8-0.7-0.70.9-0.8-0.51.0
Fe content in liver0.40.50.70.8-0.80.80.80.80.80.4-0.40.80.8-0.2
K content in liver2.22.22.4-1.51.5-1.5-1.5-1.5-1.5-1.51.5-1.5-1.61.4
Mg content in liver0.20.20.4-0.40.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.60.4
Mn content in liver0.00.00.00.0-0.10.10.10.0-0.10.1-0.0-0.00.10.1
Na content in liver2.22.32.8-1.41.4-1.4-1.4-1.4-1.4-1.71.6-1.5-1.71.6
Rb content in liver0.20.20.7-0.30.3-0.3-0.3-0.3-0.4-0.50.5-0.3-0.80.5
Se content in liver2.93.63.9-1.91.9-1.9-1.9-1.9-1.8-2.02.0-2.0-1.82.0
Sr content in liver5.55.05.4-2.32.3-2.3-2.3-2.3-2.3-2.22.3-2.3-1.82.2
Zn content in liver0.40.51.60.6-0.50.50.50.60.50.9-0.70.51.3-0.7
Bone: minimum diameter1.73.13.61.7-1.71.71.71.71.81.9-1.81.71.8-1.7
Time in familiar zone, hab. session 11.11.01.71.0-1.01.01.01.00.91.3-1.10.90.9-1.0
Time in novel zone, hab. session 13.43.35.1-1.81.8-1.8-1.8-1.8-1.8-2.31.7-1.8-1.91.5
Total zone transitions, hab. session 17.310.312.4-3.13.1-3.1-3.1-3.1-3.1-3.43.5-3.1-3.03.5
Total locomotion distance, hab. session 15.17.39.9-2.62.6-2.6-2.6-2.6-2.6-2.73.0-2.5-2.53.1
Locomotion velocity, hab. session 13.04.36.8-1.92.0-2.0-2.0-1.9-1.9-2.22.5-1.8-1.82.6
Time in familiar zone, hab. session 20.30.30.40.6-0.60.60.60.60.60.2-0.50.60.5-0.6
Time in novel zone, hab. session 20.50.50.6-0.80.7-0.7-0.7-0.7-0.8-0.30.5-0.8-0.80.6
Total zone transitions, hab. session 24.65.96.4-2.52.5-2.5-2.5-2.5-2.3-2.42.5-2.3-2.22.4
Total locomotion distance, hab. session 21.72.22.9-1.51.5-1.5-1.5-1.5-1.4-1.31.6-1.3-1.11.7
Locomotion velocity, hab. session 21.11.52.3-1.31.3-1.3-1.3-1.3-1.1-1.11.4-1.1-0.81.5
Novel to familiar place preference ratio0.10.10.5-0.40.4-0.4-0.4-0.4-0.2-0.10.4-0.2-0.00.7
Novelty place preference0.50.51.2-0.80.7-0.8-0.8-0.8-0.6-0.50.8-0.6-0.41.1
Time in novel zone, NPP test0.70.71.4-0.90.9-0.9-0.9-0.9-0.7-0.70.9-0.7-0.51.2
Total zone transitions, NPP test3.44.85.5-2.22.2-2.2-2.2-2.2-2.3-2.32.1-2.3-2.02.0
Total locomotion distance, NPP test1.42.02.2-1.51.5-1.5-1.5-1.5-1.5-1.21.4-1.5-1.11.3
Locomotion velocity, NPP test0.91.31.5-1.21.2-1.2-1.2-1.2-1.2-0.91.1-1.2-0.91.1
Intraocular pressure0.60.81.40.9-1.11.11.10.80.61.2-0.90.70.6-0.7
Delta distance traveled before/after self-admin0.50.50.70.8-0.80.80.80.60.8-0.2-0.40.90.7-0.5
Delta ambulatory time before/after self-admin0.10.10.30.3-0.30.30.30.10.3-0.50.10.30.10.0
Parametrial fat weight0.30.51.3-0.60.5-0.6-0.6-0.6-0.7-1.10.8-0.8-0.90.6
Pavlov. Cond. lever latency0.20.30.7-0.50.5-0.5-0.5-0.4-0.4-0.80.4-0.4-0.70.3
Pavlov. Cond. magazine entry latency0.30.30.7-0.50.5-0.5-0.5-0.6-0.60.00.6-0.6-0.50.9
Pavlov. Cond. change in total contacts0.60.60.8-0.80.8-0.8-0.8-0.8-0.8-0.30.8-0.9-0.70.8
Pavlov. Cond. index score0.10.10.2-0.20.2-0.2-0.2-0.2-0.20.50.2-0.2-0.00.4
Pavlov. Cond. latency score0.00.00.4-0.00.1-0.1-0.1-0.1-0.10.70.0-0.10.20.2
Pavlov. Cond. lever contacts0.20.20.90.4-0.40.40.40.40.40.9-0.40.40.6-0.3
Pavlov. Cond. magazine entry number0.20.20.40.5-0.50.50.50.50.5-0.4-0.40.50.3-0.6
Pavlov. Cond. intertrial magazine entries0.30.41.7-0.50.5-0.5-0.5-0.5-0.5-1.30.7-0.5-0.60.4
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.20.2-0.2-0.2-0.2-0.20.40.2-0.20.00.3
Pavlov. Cond. response bias0.00.10.3-0.20.2-0.2-0.2-0.2-0.10.50.1-0.20.00.3
Pavlov. Cond. lever latency0.60.81.8-0.80.8-0.8-0.8-0.8-0.9-0.80.9-0.9-1.30.9
Pavlov. Cond. magazine entry latency0.50.60.8-0.80.8-0.8-0.8-0.8-0.8-0.90.9-0.8-0.40.8
Pavlov. Cond. change in total contacts0.40.61.20.7-0.70.70.70.70.70.7-0.70.71.1-0.8
Pavlov. Cond. index score0.10.20.70.3-0.30.30.30.30.40.2-0.30.40.8-0.3
Pavlov. Cond. latency score0.50.71.70.7-0.70.70.70.70.90.7-0.70.91.3-0.7
Pavlov. Cond. lever contacts0.60.81.70.8-0.80.80.80.80.90.7-0.80.91.3-0.9
Pavlov. Cond. magazine entry number0.10.10.20.4-0.40.40.40.40.30.5-0.40.4-0.0-0.3
Pavlov. Cond. intertrial magazine entries0.20.30.50.7-0.70.70.70.70.6-0.1-0.30.70.0-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.60.3-0.30.30.30.30.40.2-0.30.40.8-0.3
Pavlov. Cond. response bias0.00.10.40.1-0.10.10.10.10.20.0-0.20.20.6-0.2
Time in closed arm before self-admin1.31.44.60.8-0.80.80.81.01.02.2-1.41.11.1-1.3
Time in closed arm after self-admin0.40.40.9-0.80.7-0.8-0.8-0.6-0.40.90.1-0.4-0.30.3
Time in open arm before self-admin0.20.20.3-0.50.5-0.5-0.5-0.5-0.1-0.10.4-0.00.00.6
Time in open arm after self-admin0.30.40.80.9-0.80.80.80.60.5-0.5-0.30.50.3-0.4
Bone: periosteal estimation5.110.513.33.2-3.23.23.23.23.23.7-3.33.13.3-3.1
Bone: periosteal perimeter5.08.410.92.9-2.92.92.92.92.93.3-2.92.82.8-2.7
Bone: post-yield work1.41.92.21.5-1.41.41.41.41.51.3-1.31.41.0-1.3
Progressive ratio test 1 active lever presses3.33.55.02.2-2.12.12.12.01.90.5-1.51.91.9-1.6
Progressive ratio test 1 breakpoint3.03.14.62.1-2.02.02.01.91.80.3-1.41.81.8-1.5
Progressive ratio test 1 inactive lever presses0.40.40.90.7-0.70.70.70.50.6-0.9-0.10.60.7-0.2
Progressive ratio test 2 active lever presses1.21.31.71.3-1.21.21.21.11.10.9-1.21.10.9-1.1
Progressive ratio test 2 breakpoint1.31.51.81.3-1.31.31.31.21.21.1-1.31.21.0-1.2
Progressive ratio test 2 inactive lever presses0.10.10.60.10.1-0.1-0.10.00.2-0.80.10.20.20.1
Incentive Sensitization - Responses0.10.10.60.2-0.40.40.4-0.00.20.7-0.40.2-0.0-0.3
Incentive Sensitization - Breakpoint0.30.31.10.5-0.60.60.60.20.41.0-0.70.40.2-0.6
Sum of active levers in priming session hrs 5-60.40.40.70.8-0.80.80.80.70.30.5-0.60.30.5-0.7
Progressive ratio0.30.30.5-0.50.5-0.7-0.7-0.5-0.50.70.2-0.5-0.50.4
Food seeking constrained by brief footshock21.025.829.75.4-5.45.45.45.35.03.8-4.95.14.9-5.0
Seeking ratio, punishment vs. effort7.79.412.03.3-3.33.53.53.13.11.4-2.83.23.1-3.0
Retroperitoneal fat weight0.30.92.0-0.60.7-0.7-0.7-0.6-1.0-1.41.0-1.1-1.20.9
Reaction time number correct0.20.32.00.1-0.00.20.20.10.41.4-0.50.30.4-0.4
Reaction time mean minus median0.70.92.1-0.90.8-0.8-0.8-0.9-0.9-1.41.1-0.8-1.01.0
Reaction time mean minus median AUC0.40.51.0-0.70.6-0.6-0.6-0.7-0.6-1.00.9-0.6-0.70.7
Reaction time num false alarms0.10.20.6-0.30.4-0.4-0.4-0.4-0.50.8-0.1-0.6-0.4-0.1
Reaction time num false alarms AUC0.10.10.90.00.0-0.1-0.1-0.1-0.40.9-0.3-0.5-0.2-0.3
Reaction time trials correct on left0.20.32.00.1-0.00.20.20.10.41.4-0.50.30.4-0.4
Reaction time trials on left0.20.32.20.1-0.10.20.20.20.51.5-0.60.30.5-0.5
Reaction time mean0.00.10.10.3-0.30.40.40.10.30.2-0.20.30.0-0.2
Reaction time mean AUC0.10.10.20.4-0.40.40.40.20.40.1-0.20.30.1-0.2
Median of all reaction times0.30.40.60.7-0.70.80.80.50.50.8-0.60.50.4-0.6
Reaction time omissions0.20.20.70.4-0.40.50.50.50.50.8-0.40.50.4-0.2
Reaction time false alarm rate0.20.30.7-0.30.3-0.5-0.5-0.4-0.8-0.20.4-0.8-0.70.3
Reaction time premature initiation rate0.20.20.7-0.40.2-0.2-0.2-0.5-0.80.20.3-0.7-0.80.4
Reaction time premature initiations0.10.21.5-0.1-0.00.10.1-0.3-0.41.2-0.3-0.3-0.4-0.1
Std. dev. reaction times0.50.71.1-0.80.7-0.7-0.7-0.9-0.8-0.90.9-0.8-1.00.8
Reaction time trials completed0.20.32.20.1-0.10.20.20.20.51.5-0.60.30.5-0.5
Reaction time trials AUC0.20.32.10.2-0.20.30.30.20.51.4-0.60.40.5-0.5
Run reversals in cocaine runway, females0.00.00.1-0.00.00.00.00.1-0.10.4-0.0-0.2-0.20.1
Run reversals in cocaine runway, males0.20.21.0-0.30.3-0.3-0.3-0.2-0.5-1.00.5-0.4-0.50.3
Latency to leave start box in cocaine runway0.50.51.10.8-0.80.60.60.80.61.0-0.70.50.6-0.6
Latency to leave start box in cocaine runway, F0.10.10.70.3-0.30.20.20.40.30.8-0.40.20.3-0.2
Latency to leave start box in cocaine runway, M0.90.91.21.1-1.11.11.10.90.80.7-0.90.70.8-0.9
Std. dev. time between licks in bursts0.60.71.40.8-0.80.80.80.80.80.8-0.80.81.2-0.8
Total sessions with >9 infusions0.00.00.10.4-0.10.10.10.20.3-0.3-0.20.30.2-0.2
Short access day 1 total inactive lever presses0.10.10.7-0.00.1-0.1-0.1-0.20.0-0.90.2-0.1-0.30.1
Short access day 10 total inactive lever presses0.60.70.9-1.00.9-0.9-0.9-0.9-0.7-0.70.8-0.7-0.70.7
Short access day 1 total infusions0.10.11.00.00.2-0.2-0.2-0.1-0.2-1.00.4-0.2-0.40.2
Short access day 10 total infusions1.11.21.71.2-1.11.11.11.01.20.7-0.91.21.3-0.9
Short access total infusions1.11.21.71.3-1.11.11.11.21.20.3-0.91.21.2-1.0
Short access day 1 locomotion0.80.91.3-0.91.0-0.9-0.9-0.8-0.9-0.81.0-0.9-1.01.1
Short access day 10 total locomotion0.10.10.3-0.40.3-0.3-0.3-0.4-0.50.30.2-0.5-0.40.5
Short access total locomotion0.10.10.3-0.20.2-0.2-0.2-0.3-0.4-0.40.4-0.3-0.20.5
One hour access (0.3 mA shock)1.01.21.71.3-1.11.11.11.11.10.5-1.11.11.1-1.3
Compulsive drug intake0.10.10.20.5-0.40.30.30.40.4-0.3-0.30.30.2-0.5
One hour access (shock baseline)0.81.01.11.0-1.11.11.10.91.00.9-1.01.01.0-0.9
Social response proportion2.02.12.6-1.61.6-1.5-1.5-1.5-1.5-1.61.4-1.4-1.31.1
Social responses0.20.20.5-0.60.5-0.4-0.4-0.7-0.70.20.2-0.6-0.50.0
Social time0.30.41.0-0.60.5-0.5-0.5-0.6-1.0-0.40.5-0.8-1.00.4
Soleus weight1.75.16.22.3-2.32.32.32.32.32.2-2.12.22.5-1.9
Bone: stiffness0.20.30.40.5-0.50.50.50.50.50.6-0.60.50.3-0.5
Tibialis anterior weight8.228.130.35.3-5.35.35.35.35.25.2-5.55.25.3-5.5
Time to tail flick, vehicle, before self-admin0.30.30.5-0.50.5-0.5-0.5-0.7-0.6-0.30.6-0.5-0.40.7
Time to tail flick, vehicle, after self-admin0.10.10.30.1-0.10.10.10.20.40.4-0.20.30.6-0.1
Time to tail flick, test, before self-admin0.40.41.50.4-0.40.40.40.50.31.2-0.80.40.6-0.7
Time to tail flick, test, after self-admin0.40.40.8-0.90.9-0.9-0.9-0.7-0.40.60.3-0.4-0.10.5
Delta time to tail flick, vehicle, before/after SA0.40.40.80.5-0.50.50.50.70.90.5-0.60.80.8-0.7
Delta time to tail flick, test, before/after SA1.91.72.4-1.51.5-1.5-1.5-1.5-1.0-0.81.3-1.0-1.01.4
Tibia length2.15.96.72.5-2.62.62.62.52.62.0-2.42.52.0-2.3
Ambulatory time before self-admin0.50.60.9-0.90.9-0.9-0.9-0.9-0.7-0.30.5-0.7-0.60.5
Ambulatory time after self-admin0.10.10.20.3-0.30.30.30.30.4-0.0-0.30.40.5-0.4
Bone: tissue strength1.01.01.3-1.01.0-1.0-1.0-1.0-1.0-1.11.0-1.0-1.00.9
Total heroin consumption0.10.10.20.2-0.20.20.20.3-0.5-0.20.1-0.4-0.50.3
Bone: trabecular number0.20.30.40.6-0.70.70.70.70.60.6-0.50.50.4-0.3
Bone: trabecular spacing0.40.51.20.6-0.60.60.60.60.60.8-0.90.60.8-1.1
Bone: trabecular thickness0.20.20.6-0.40.5-0.5-0.5-0.5-0.50.00.5-0.4-0.50.8
Bone: trabecular tissue density4.15.76.5-2.52.5-2.5-2.5-2.5-2.4-2.12.3-2.4-2.42.0
Water consumed over 24 hours2.22.63.61.6-1.61.61.61.61.61.7-1.61.61.9-1.4
Number of responses in last shaping day0.60.70.80.9-0.90.90.90.80.80.3-0.80.80.8-0.9