Hub : Genes

Naa40

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Naa40 0.08 0.05 3.1e-07 0.07 0.06 0.05 0.06 4.6e-08 7.9e-07 1.4e-06 8.3e-07
2 Liver alternative polyA XM_039084072.1 0.03 0.02 9.7e-03 0.01 0 0 0.01 5.7e-02 7.8e-02 8.7e-02 4.2e-02
3 Adipose mRNA stability Naa40 0.08 0.05 5.6e-06 0.03 0.04 0.04 0.04 1.5e-04 4.6e-05 2.7e-05 5.2e-05
4 Liver alternative polyA XM_039084082.1 0.03 0.02 6.3e-03 0.01 0.01 0.01 0.02 9.1e-03 8.7e-03 1.7e-02 6.5e-03
5 OFC alternative polyA NM_001108518.1 0.2 0.13 6.3e-03 0.1 0.04 0.04 0 2.6e-03 5.2e-02 4.5e-02 3.2e-01
6 Adipose gene expression Naa40 0.05 0.04 1.6e-03 0.01 0.02 0.01 0.01 2.5e-02 4.6e-03 1.2e-02 7.7e-03
7 Brain alternative polyA XM_039084072.1 0.04 0.03 9.0e-04 0.02 0.03 0.03 0.03 4.1e-03 4.2e-04 4.0e-04 4.4e-04
8 Brain alternative polyA NM_001108518.1 0.04 0.03 8.9e-04 0.02 0.03 0.03 0.03 4.0e-03 3.6e-04 3.4e-04 4.3e-04
9 Brain mRNA stability Naa40 0.12 0.06 4.7e-10 0.1 0.1 0.1 0.1 4.1e-09 6.0e-10 1.1e-09 6.0e-10
10 OFC alternative polyA XM_039084072.1 0.22 0.13 4.3e-03 0.05 0.01 0.03 -0.01 2.1e-02 1.4e-01 7.2e-02 5.1e-01
11 OFC isoform ratio NM_001108518.1 0.27 0.17 4.5e-03 0.03 -0 -0.01 -0.01 6.9e-02 3.4e-01 6.5e-01 9.7e-01
12 PL alternative polyA NM_001108518.1 0.06 0.03 1.4e-05 0.05 0.05 0.05 0.05 3.6e-06 6.5e-06 6.2e-06 7.7e-06
13 PL alternative polyA XM_039084082.1 0.06 0.03 8.0e-06 0.05 0.05 0.05 0.05 1.7e-06 4.2e-06 2.6e-06 3.3e-06
14 PL alternative polyA NM_001108518.1 0.06 0.03 1.3e-05 0.05 0.04 0.04 0.04 2.6e-06 9.1e-06 1.1e-05 1.0e-05
15 PL alternative polyA XM_039084072.1 0.06 0.03 7.5e-06 0.05 0.05 0.05 0.05 1.5e-06 5.1e-06 4.8e-06 4.1e-06
16 OFC intron excision ratio chr1_204416185_204417376 0.18 0.1 9.8e-03 0.09 0.07 0.02 0.08 4.1e-03 9.7e-03 1.1e-01 6.7e-03
17 Brain alternative polyA XM_039084082.1 0.04 0.02 2.5e-03 0.03 0.03 0.03 0.02 1.7e-03 1.2e-03 1.9e-03 4.9e-03
18 Brain alternative polyA NM_001108518.1 0.04 0.02 2.5e-03 0.03 0.03 0.02 0.02 2.0e-03 1.1e-03 2.4e-03 4.6e-03
19 Brain isoform ratio NM_001108518.1 0.03 0.02 4.8e-03 0.01 0.02 0.02 0.01 7.9e-02 3.6e-03 7.1e-03 2.2e-02
20 OFC intron excision ratio chr1_204417938_204424043 0.19 0.11 6.8e-03 0.07 0.08 0.01 0.09 8.0e-03 6.7e-03 1.6e-01 4.5e-03
21 PL isoform ratio NM_001108518.1 0.06 0.03 1.3e-05 0.05 0.04 0.04 0.04 6.3e-06 6.8e-05 4.0e-05 5.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.01.74.2-0.60.8-0.51.3-0.90.41.0-1.1-0.10.5-0.5-2.02.0-2.02.02.0-1.21.31.31.7-1.6
Area under the delay curve0.30.40.9-0.40.4-0.30.6-0.90.10.4-0.40.20.9-0.9-0.70.7-0.70.70.6-0.50.50.60.6-0.6
BMI with tail4.012.829.1-2.84.0-3.14.8-1.5-0.61.6-1.61.61.2-1.2-5.45.4-5.45.45.1-2.42.62.94.4-4.2
BMI without tail1.83.711.9-2.43.1-2.33.5-0.6-1.00.3-0.21.60.0-0.0-2.62.6-2.62.62.7-0.50.60.81.5-1.6
Body weight2.29.322.7-4.04.5-4.24.80.6-2.7-0.80.83.4-1.41.4-3.93.9-3.93.93.9-0.00.30.53.2-2.8
Weight adjusted by age0.91.02.3-1.51.5-1.51.41.3-0.9-0.80.70.9-0.60.6-1.01.0-1.01.00.80.2-0.1-0.01.0-1.1
Bone surface2.95.112.8-1.92.5-2.12.80.2-0.20.8-0.80.4-0.40.4-3.63.6-3.63.63.6-1.31.41.62.7-2.4
Bone volume2.03.58.6-0.81.2-0.91.6-0.30.61.4-1.4-0.40.1-0.1-2.92.9-2.92.92.9-1.61.71.82.4-2.2
Breakpoint value in progressive ratio session1.21.32.8-1.61.7-1.61.51.4-1.2-0.90.81.1-1.61.6-0.80.8-0.80.81.00.8-0.7-0.60.3-0.2
Number of licking bursts0.10.10.3-0.30.5-0.50.40.4-0.2-0.30.30.2-0.20.2-0.30.3-0.30.30.30.00.00.00.2-0.3
Context. condit. distance diff. score0.60.71.90.9-0.71.1-0.6-1.31.00.9-0.9-0.81.4-1.40.2-0.20.2-0.2-0.4-0.90.80.80.1-0.4
Locomotion velocity, session 10.20.20.5-0.30.6-0.40.7-0.7-0.20.1-0.10.40.7-0.7-0.40.4-0.40.40.3-0.10.10.20.0-0.0
Locomotion distance, session 10.81.11.9-0.71.0-0.71.3-1.2-0.10.6-0.60.51.0-1.0-1.41.4-1.41.41.4-0.80.80.91.1-1.1
Locomotion velocity, session 21.21.43.4-1.71.8-1.81.80.4-1.2-0.50.51.4-0.40.4-1.31.3-1.31.31.30.1-0.00.11.1-1.1
Locomotion distance, session 20.30.51.3-0.91.0-1.01.1-0.5-0.6-0.10.20.90.5-0.5-0.80.8-0.80.80.80.0-0.00.10.3-0.1
Locomotion velocity, session 32.53.05.70.60.10.60.7-2.41.12.0-2.0-0.41.9-1.9-1.71.7-1.71.71.6-2.12.12.12.2-2.3
Locomotion distance, session 30.10.10.40.20.00.10.2-0.60.10.4-0.40.10.4-0.4-0.40.4-0.40.40.3-0.40.40.50.5-0.5
Stereotopy head waving bouts, day 32.12.46.40.7-0.00.80.6-2.51.31.8-1.8-0.72.3-2.3-1.21.2-1.21.21.3-2.02.02.01.6-1.7
Stereotopy head waving duration, day 30.91.12.81.1-0.61.0-0.2-1.71.21.4-1.3-0.91.4-1.4-0.50.5-0.50.50.5-1.31.31.20.9-0.8
Locomotion velocity, session 71.31.53.10.8-0.41.00.1-1.81.21.5-1.5-0.81.4-1.4-0.90.9-0.90.91.0-1.61.61.51.5-1.3
Locomotion distance, session 70.30.41.4-0.00.00.20.4-1.20.20.4-0.40.11.2-1.2-0.30.3-0.30.30.3-0.70.70.70.9-0.5
Stereotopy head waving bouts, day 70.70.81.90.70.00.50.1-0.71.01.3-1.4-1.00.3-0.3-1.01.0-1.01.00.9-1.11.11.10.5-1.1
Stereotopy head waving duration, day 70.70.92.0-0.71.2-0.91.10.4-0.20.4-0.40.3-0.80.8-1.41.4-1.41.41.3-0.30.40.40.8-1.2
Locomotion velocity, session 80.60.72.3-1.41.5-1.41.50.1-0.8-0.70.70.90.2-0.2-0.50.5-0.50.50.50.6-0.6-0.5-0.80.8
Locomotion distance, session 81.11.73.60.30.40.30.8-1.81.11.4-1.4-0.71.9-1.9-1.41.4-1.41.41.3-1.51.51.50.8-1.0
Degree of sensitization distance0.70.71.7-0.00.20.20.6-1.20.60.7-0.7-0.31.3-1.3-0.70.7-0.70.70.7-1.11.11.11.3-1.0
Degree of sensitization stereotypy0.50.61.5-0.20.6-0.40.60.20.20.6-0.7-0.2-0.60.6-1.21.2-1.21.21.2-0.50.60.60.5-1.0
Conditioned locomotion0.60.72.3-1.41.5-1.41.40.7-1.0-0.60.71.1-0.30.3-0.70.7-0.70.70.60.4-0.4-0.30.2-0.1
Cocaine response after cond. corrected0.50.62.30.8-1.01.0-0.7-1.50.70.7-0.7-0.51.4-1.40.3-0.30.3-0.3-0.4-0.60.50.5-0.00.3
Cocaine response after cond. not corrected0.40.42.20.6-0.80.8-0.5-1.50.60.7-0.6-0.41.2-1.20.0-0.00.0-0.0-0.1-0.50.50.5-0.00.2
Cocaine response before conditioning0.30.31.3-0.70.4-0.70.40.9-0.5-0.50.40.3-1.11.1-0.40.4-0.40.40.60.4-0.4-0.4-0.1-0.1
Saline control response1.92.56.9-2.62.5-2.52.21.3-2.2-1.91.82.3-1.51.5-0.60.6-0.60.60.81.2-1.1-1.00.4-0.3
Bone: connectivity density1.62.56.0-1.61.8-1.72.1-0.0-0.50.3-0.30.8-0.00.0-2.32.3-2.32.32.5-0.80.91.12.1-2.0
Bone: cortical apparent density0.91.22.1-0.70.3-0.6-0.11.3-1.1-1.51.40.9-1.21.21.2-1.21.2-1.2-1.01.3-1.3-1.3-0.90.7
Bone: cortical area0.40.61.8-0.50.9-0.80.90.5-0.20.1-0.20.3-0.40.4-1.11.1-1.11.11.0-0.40.50.51.3-1.2
Bone: cortical porosity0.10.10.6-0.10.4-0.20.30.2-0.1-0.10.10.0-0.50.5-0.10.1-0.10.1-0.10.4-0.3-0.3-0.30.8
Bone: cortical porosity0.40.40.8-0.70.9-0.80.70.6-0.6-0.60.60.5-0.90.9-0.20.2-0.20.20.00.8-0.7-0.7-0.50.9
Bone: cortical thickness2.23.67.4-2.31.9-2.41.32.3-2.7-2.62.52.6-2.42.40.8-0.80.8-0.8-0.42.2-2.1-2.0-0.50.5
Bone: cortical thickness0.91.02.4-1.20.7-1.10.50.7-1.5-1.51.51.6-0.70.70.7-0.70.7-0.7-0.51.3-1.3-1.2-0.50.7
Bone: cortical tissue density1.11.42.5-0.80.4-0.7-0.11.4-1.2-1.61.61.0-1.31.31.3-1.31.3-1.3-1.11.5-1.5-1.5-1.00.8
Condit. Reinf. active minus inactive responses0.20.20.8-0.50.9-0.50.70.4-0.6-0.30.30.6-0.60.6-0.10.1-0.10.1-0.10.3-0.3-0.30.2-0.5
Condit. Reinf. active-inactive response ratio0.40.40.8-0.20.4-0.30.00.8-0.6-0.70.70.4-0.90.90.5-0.50.5-0.5-0.70.8-0.8-0.9-0.80.5
Condit. Reinf. active responses0.20.21.40.00.40.00.4-0.20.00.4-0.50.1-0.20.2-0.60.6-0.60.60.3-0.40.50.40.9-1.2
Condit. Reinf. inactive responses0.91.12.00.5-0.30.60.1-1.21.01.4-1.4-0.70.8-0.8-1.11.1-1.11.11.1-1.31.41.41.4-1.3
Incentive salience index mean0.30.41.4-0.61.1-0.71.1-0.0-0.5-0.0-0.00.6-0.10.1-0.70.7-0.70.70.5-0.20.20.30.9-1.2
Condit. Reinf. lever presses0.50.72.0-0.40.8-0.50.9-0.3-0.10.4-0.40.30.2-0.2-1.21.2-1.21.21.2-0.70.70.81.2-1.4
Condit. Reinf. active minus inactive responses0.40.51.50.9-0.40.8-0.3-0.61.11.1-1.1-1.2-0.00.0-0.50.5-0.50.50.6-0.70.70.70.1-0.1
Condit. Reinf. active-inactive response ratio2.42.56.21.6-0.91.6-0.5-1.32.22.4-2.5-2.20.8-0.8-1.41.4-1.41.41.2-1.91.91.80.8-1.0
Condit. Reinf. active responses0.00.00.20.20.3-0.00.3-0.00.20.1-0.1-0.2-0.40.4-0.20.2-0.20.20.4-0.10.10.10.0-0.0
Condit. Reinf. inactive responses0.91.22.9-1.01.0-1.20.80.7-1.4-1.71.71.4-0.60.60.8-0.80.8-0.8-0.41.3-1.3-1.2-0.60.8
Condit. Reinf. lever presses0.81.13.8-1.01.4-1.31.40.6-0.4-0.20.10.4-0.90.9-1.51.5-1.51.52.0-0.20.30.41.1-0.9
Condit. Reinf. lever reinforcers received0.10.10.5-0.10.4-0.30.30.3-0.0-0.10.1-0.1-0.70.7-0.30.3-0.30.30.50.1-0.1-0.10.0-0.1
Conditioned reinforcement - actives0.60.62.91.0-0.91.0-0.9-0.31.50.9-0.9-1.70.5-0.5-0.00.0-0.00.00.1-0.80.80.7-0.50.5
Conditioned reinforcement - inactives2.93.39.43.1-2.92.7-2.9-1.12.41.7-1.7-2.51.2-1.21.1-1.11.1-1.1-1.4-1.61.51.40.5-0.5
Conditioned locomotion4.45.315.53.7-3.93.7-3.8-1.72.71.7-1.7-2.81.8-1.81.9-1.91.9-1.9-2.1-1.61.51.30.1-0.2
Patch foraging indifference point 0 sec0.10.10.60.3-0.10.2-0.30.1-0.10.1-0.10.1-0.50.50.1-0.10.1-0.1-0.4-0.10.10.10.8-0.6
Patch foraging indifference point AUC1.61.84.7-2.22.1-1.91.82.1-1.2-0.90.81.1-1.71.7-1.11.1-1.11.11.10.6-0.5-0.40.8-0.7
Delay disc. indifference point, 0s delay1.01.13.8-0.20.40.00.8-1.80.51.0-0.9-0.11.9-1.9-1.01.0-1.01.01.0-1.01.01.00.4-0.6
Delay disc. indifference point, 16s delay0.50.61.51.0-0.81.0-0.6-0.70.80.8-0.8-0.70.6-0.60.1-0.10.1-0.1-0.0-1.00.90.91.2-1.0
Delay disc. indifference point, 2s delay0.70.81.80.00.10.10.3-1.00.70.9-0.9-0.51.3-1.3-1.01.0-1.01.01.0-1.01.11.10.6-0.8
Delay disc. indifference point, 24s delay0.40.31.0-0.30.1-0.3-0.00.3-0.7-1.01.00.70.1-0.10.8-0.80.8-0.8-0.80.5-0.5-0.50.10.0
Delay disc. indifference point, 4s delay0.30.30.9-0.60.7-0.40.9-0.9-0.5-0.00.10.80.8-0.8-0.30.3-0.30.30.2-0.10.10.20.4-0.5
Delay disc. indifference point, 8s delay0.20.20.8-0.60.5-0.40.6-0.8-0.10.00.00.30.9-0.9-0.30.3-0.30.30.20.0-0.00.0-0.40.4
Indifference point function ln k2.83.99.42.9-2.92.9-2.5-3.11.81.4-1.3-1.52.6-2.61.6-1.61.6-1.6-1.8-0.90.80.6-1.00.9
Indifference point function log k2.83.99.42.9-2.92.9-2.5-3.11.81.4-1.3-1.52.6-2.61.6-1.61.6-1.6-1.8-0.90.80.6-1.00.9
Patch foraging total patch changes 0 sec0.10.20.60.1-0.10.1-0.30.3-0.4-0.30.30.4-0.80.80.5-0.50.5-0.5-0.80.3-0.3-0.40.4-0.2
Patch foraging total patch changes 12 sec2.33.07.0-2.62.3-2.52.02.1-2.1-1.41.32.2-2.22.2-1.21.2-1.21.21.00.9-0.8-0.71.5-1.1
Patch foraging total patch changes 18 sec0.40.51.7-1.01.0-0.90.91.0-0.6-0.50.50.5-1.31.3-0.50.5-0.50.50.50.4-0.3-0.30.5-0.2
Patch foraging total patch changes 24 sec1.82.24.6-1.92.0-2.01.61.9-2.0-1.41.42.0-1.71.7-0.60.6-0.60.60.30.6-0.5-0.52.1-1.7
Patch foraging total patch changes 6 sec0.50.72.0-1.31.4-1.21.40.4-0.9-0.50.51.1-0.50.5-0.80.8-0.80.80.60.1-0.00.11.3-1.0
Patch foraging time to switch 0 sec1.62.46.1-1.01.5-1.21.9-0.50.20.7-0.80.10.7-0.7-2.32.3-2.32.32.5-1.31.41.52.0-1.9
Patch foraging water rate 0 sec1.93.08.12.2-2.62.3-2.8-0.30.7-0.10.1-0.90.0-0.02.6-2.62.6-2.6-2.60.5-0.6-0.8-1.31.2
Patch foraging water rate 12 sec3.35.012.72.9-3.12.8-3.3-1.30.8-0.00.1-0.90.9-0.93.2-3.23.2-3.2-3.60.5-0.7-0.9-1.72.0
Patch foraging water rate 18 sec1.11.53.21.6-1.81.7-1.7-1.50.50.3-0.2-0.41.2-1.21.5-1.51.5-1.5-1.7-0.1-0.0-0.1-0.80.6
Patch foraging water rate 24 sec1.41.95.61.9-2.41.8-2.3-1.30.80.4-0.3-0.90.9-0.91.7-1.71.7-1.7-1.90.1-0.2-0.3-1.31.1
Patch foraging water rate 6 sec1.72.56.11.7-2.21.9-2.2-1.00.3-0.20.2-0.30.7-0.72.5-2.52.5-2.5-2.50.5-0.6-0.8-1.11.2
Seeking ratio, delayed vs. immediate footshock0.10.10.60.3-0.20.3-0.40.0-0.1-0.10.20.1-0.10.10.8-0.80.8-0.8-0.40.1-0.1-0.10.1-0.2
Distance traveled before self-admin0.40.41.2-0.20.6-0.40.60.4-0.30.1-0.20.3-1.01.0-0.80.8-0.80.80.8-0.20.20.31.1-0.9
Distance traveled after self-admin0.20.21.20.00.0-0.2-0.20.8-0.3-0.30.30.1-1.11.1-0.00.0-0.00.0-0.10.4-0.3-0.3-0.00.1
Extensor digitorum longus weight3.212.532.4-5.35.7-5.55.52.5-3.9-2.02.04.3-2.52.5-3.63.6-3.63.63.51.0-0.7-0.42.8-2.7
Bone: elastic displacement1.41.64.40.5-1.00.7-1.20.1-0.4-0.80.80.2-0.00.02.0-2.02.0-2.0-2.11.1-1.1-1.2-1.61.4
Bone: elastic work1.01.33.3-1.41.1-1.40.90.8-1.7-1.61.61.8-0.70.70.7-0.70.7-0.7-0.71.3-1.3-1.3-0.60.4
Bone: endosteal estimation3.47.412.01.6-0.61.50.3-3.02.83.4-3.4-2.33.2-3.2-2.72.7-2.72.72.3-3.53.43.52.6-2.4
Bone: endosteal perimeter4.49.015.32.2-0.91.90.0-3.13.53.9-3.9-3.13.0-3.0-3.03.0-3.03.02.7-3.83.83.82.6-2.5
Epididymis fat weight1.53.57.12.5-2.02.4-1.3-2.72.22.6-2.6-1.91.6-1.6-0.60.6-0.60.60.4-2.32.22.11.8-1.3
Delta time in closed arm before/after self-admin0.40.42.2-0.80.1-0.20.3-0.7-1.1-0.60.61.50.1-0.10.6-0.60.6-0.6-0.30.4-0.4-0.40.5-0.4
Delta time in open arm before/after self-admin0.20.21.40.30.3-0.2-0.01.2-0.1-0.20.1-0.1-0.90.9-0.10.1-0.10.10.10.00.0-0.00.5-0.7
Diff in mean of infusions in LGA sessions0.91.04.2-0.80.6-0.60.30.9-1.2-0.80.81.1-2.12.10.5-0.50.5-0.5-0.41.2-1.2-1.2-0.10.5
Delay discount exponential model param0.20.30.70.4-0.50.4-0.60.70.0-0.20.2-0.2-0.90.90.6-0.60.6-0.6-0.50.4-0.4-0.4-0.50.5
Extinction: sum of active levers before priming2.12.15.9-2.12.4-2.22.31.4-1.5-0.70.71.5-1.51.5-1.41.4-1.41.41.40.6-0.5-0.30.9-0.8
Active lever presses in extinction session 61.11.13.6-1.41.2-1.31.01.8-1.0-0.80.70.8-1.91.9-0.50.5-0.50.50.70.7-0.6-0.60.3-0.4
Bone: final force1.62.55.4-1.82.2-2.02.30.5-0.8-0.00.01.1-0.40.4-2.22.2-2.22.22.2-0.50.60.82.0-1.8
Bone: final moment1.42.34.7-1.72.1-1.92.20.5-0.8-0.0-0.01.1-0.40.4-2.12.1-2.12.12.0-0.50.60.71.9-1.8
Food consumed during 24 hour testing period0.10.11.00.1-0.2-0.0-0.51.00.0-0.40.4-0.3-0.40.40.3-0.30.3-0.3-0.50.2-0.2-0.20.0-0.1
Glucose2.23.36.41.8-1.72.0-1.0-2.42.42.3-2.3-2.12.5-2.5-0.90.9-0.90.90.8-2.22.12.10.9-0.7
Heart weight1.42.06.01.9-2.42.1-2.0-2.11.41.4-1.3-1.21.8-1.80.6-0.60.6-0.6-0.9-1.11.00.9-0.0-0.1
Delay discount hyperbolic model param0.30.30.80.5-0.60.4-0.70.80.0-0.30.3-0.2-0.90.90.7-0.70.7-0.7-0.60.5-0.5-0.5-0.60.6
Intermittent access intake day 1-15 change0.50.51.41.0-1.00.9-1.20.40.80.3-0.3-1.2-0.60.60.6-0.60.6-0.6-0.80.0-0.1-0.1-0.90.8
Intermittent access intake escalation0.40.41.10.9-0.90.9-1.00.20.70.4-0.4-1.0-0.60.60.5-0.50.5-0.5-0.6-0.10.0-0.0-0.60.6
Intermittent access intake escalation 20.30.31.20.6-0.70.5-0.90.80.3-0.0-0.0-0.6-1.11.10.5-0.50.5-0.5-0.70.1-0.1-0.2-0.20.2
Intermitt. access day 1 inactive lever presses1.31.43.31.8-1.61.7-1.5-1.21.71.3-1.3-1.81.1-1.10.5-0.50.5-0.5-0.6-1.11.00.9-0.20.2
Intermitt. access day 15 inactive lever presses2.22.45.12.3-2.12.3-2.0-1.31.91.9-1.9-1.81.0-1.00.4-0.40.4-0.4-0.5-1.81.81.61.6-1.4
Intermitt. access escalation Index0.90.82.21.3-1.51.3-1.3-1.50.60.7-0.7-0.31.1-1.10.7-0.70.7-0.7-0.7-0.50.40.40.3-0.1
Intermittent access day 1 total infusions6.27.214.82.9-2.42.7-1.5-3.83.23.6-3.5-2.73.5-3.5-1.11.1-1.11.10.9-3.43.33.21.8-1.9
Intermittent access day 15 total infusions5.66.213.23.6-3.23.3-2.7-3.13.53.4-3.4-3.42.3-2.3-0.20.2-0.20.2-0.2-2.82.72.50.6-0.6
Intermittent access terminal intake (last 3 days)5.56.113.03.1-2.52.7-1.9-3.13.23.6-3.6-3.02.1-2.1-1.01.0-1.01.00.7-3.13.02.91.5-1.6
Intermittent access total infusions5.15.711.62.9-2.42.7-1.7-3.23.13.4-3.4-2.82.4-2.4-0.90.9-0.90.90.7-3.02.92.81.3-1.4
Intermittent access day 1 locomotion4.95.112.22.0-1.72.0-0.9-3.52.32.9-2.8-1.73.1-3.1-1.21.2-1.21.20.9-2.92.82.82.0-2.1
Intermittent access day 15 total locomotion3.43.67.42.7-2.52.5-2.0-2.22.42.4-2.4-2.31.8-1.8-0.20.2-0.20.2-0.1-2.32.22.11.2-1.4
Intermittent access total locomotion7.48.415.63.1-2.63.0-1.8-3.73.44.0-3.9-3.03.0-3.0-1.21.2-1.21.21.0-3.83.83.62.6-2.8
Intermittent access standard deviation0.70.72.21.5-1.41.3-1.4-0.51.10.8-0.8-1.4-0.40.40.5-0.50.5-0.5-0.7-0.30.30.2-0.80.8
Left kidney weight0.31.03.21.5-1.81.4-1.5-1.01.01.2-1.2-1.00.4-0.4-0.00.0-0.00.0-0.1-1.01.00.90.6-0.8
Right kidney weight0.30.81.61.2-1.00.9-0.9-0.40.91.2-1.2-0.90.0-0.0-0.60.6-0.60.60.4-1.21.21.11.2-1.2
Cocaine induced anxiety0.20.20.40.00.2-0.10.20.00.30.6-0.6-0.30.2-0.2-0.50.5-0.50.50.3-0.50.50.50.6-0.6
Post-drug Anxiety0.40.41.3-0.81.1-0.91.00.8-0.2-0.0-0.00.1-0.60.6-0.80.8-0.80.80.8-0.00.10.10.5-0.3
Baseline Anxiety1.31.42.5-1.51.4-1.51.31.1-1.6-1.41.41.6-1.61.6-0.40.4-0.40.40.51.2-1.1-1.1-0.20.3
Tail length1.23.66.4-2.31.9-2.01.41.9-2.5-2.52.52.4-2.42.40.9-0.90.9-0.9-0.52.4-2.3-2.2-1.11.1
Length with tail1.03.88.7-2.82.5-2.92.22.0-2.9-2.22.22.9-2.42.4-0.70.7-0.70.70.91.6-1.5-1.40.7-0.5
Length without tail0.61.43.1-1.51.3-1.81.40.8-1.5-0.90.91.7-1.11.1-1.21.2-1.21.21.20.3-0.2-0.11.5-1.1
Times rat made contact with spout0.91.01.9-1.11.0-1.10.70.9-1.2-1.41.41.1-0.90.90.7-0.70.7-0.7-0.61.3-1.2-1.2-0.90.8
Lifetime Intake4.14.610.22.6-2.22.4-1.5-3.22.73.1-3.1-2.42.2-2.2-0.80.8-0.80.80.7-2.62.52.41.0-1.0
Liver weight, left0.30.41.20.10.30.30.6-1.10.60.8-0.8-0.40.4-0.4-0.80.8-0.80.81.0-0.50.50.5-0.20.3
Liver weight, right0.61.02.0-0.30.8-0.21.1-1.40.10.8-0.80.31.2-1.2-1.21.2-1.21.20.9-0.90.91.01.1-0.9
Locomotor activity1.01.53.41.2-1.41.3-1.4-0.90.0-0.40.5-0.1-0.10.11.8-1.81.8-1.8-1.80.8-0.9-1.0-1.41.7
Locomotor testing distance1.11.84.61.1-1.51.3-1.5-1.2-0.1-0.40.50.10.5-0.52.1-2.12.1-2.1-2.10.7-0.8-0.9-1.31.5
Locomotor testing rearing0.60.92.61.1-1.31.3-1.2-1.30.30.3-0.3-0.30.5-0.51.2-1.21.2-1.2-1.60.2-0.3-0.4-0.91.1
Locomotion in novel chamber2.83.58.83.0-2.42.6-2.1-1.92.72.3-2.3-2.81.5-1.50.1-0.10.1-0.1-0.3-2.12.01.90.5-0.7
Locomotion in novel chamber post-restriction1.41.74.92.0-2.02.2-1.7-1.51.91.5-1.5-1.91.0-1.00.7-0.70.7-0.7-0.6-0.90.80.7-0.70.6
Fecal boli incidents, locomotor time 10.50.51.10.30.10.10.20.20.90.8-0.9-1.0-0.10.1-1.01.0-1.01.01.1-0.70.80.80.5-0.4
Change in fecal boli incidents, locomotor task0.40.42.3-0.50.4-0.40.6-1.0-0.2-0.20.30.51.5-1.50.0-0.00.0-0.0-0.20.1-0.1-0.0-0.50.5
Time >=10cm from walls, locomotor time 13.33.47.11.1-0.51.20.0-1.92.42.6-2.7-2.21.6-1.6-1.91.9-1.91.91.9-2.22.32.20.9-0.9
Bouts of movement, locomotor time 13.23.58.3-0.80.3-1.0-0.52.9-1.6-2.42.41.0-2.72.71.5-1.51.5-1.5-1.62.3-2.3-2.3-1.41.6
Total resting periods, locomotor time 12.22.46.7-0.50.0-0.7-0.62.6-1.3-2.02.00.7-2.42.41.3-1.31.3-1.3-1.41.9-1.8-1.9-1.01.2
Rest time, locomotor task time 10.80.91.91.2-1.21.2-1.40.10.70.0-0.0-1.00.4-0.41.3-1.31.3-1.3-1.40.2-0.2-0.3-1.11.0
Distance moved, locomotor task time 10.60.61.5-0.20.9-0.61.1-0.8-0.00.6-0.60.30.0-0.0-1.21.2-1.21.21.2-0.50.60.60.7-0.6
Vertical activity count, locomotor time 10.60.72.31.3-0.71.1-0.4-1.51.11.3-1.3-0.90.8-0.8-0.00.0-0.00.00.1-0.80.80.7-0.00.2
Time >=10cm from walls, locomotor time 20.10.10.60.10.20.10.00.50.50.3-0.4-0.7-0.60.6-0.20.2-0.20.20.2-0.10.10.1-0.40.2
Bouts of movement, locomotor time 20.60.72.2-0.60.3-0.50.01.3-1.1-1.01.01.0-1.51.50.4-0.40.4-0.4-0.40.9-0.9-0.80.2-0.1
Total resting periods, locomotor time 20.30.31.3-0.40.1-0.3-0.10.9-0.7-0.60.60.6-1.11.10.2-0.20.2-0.2-0.30.6-0.6-0.60.2-0.1
Rest time, locomotor task time 21.31.53.31.6-1.61.8-1.3-1.71.71.5-1.5-1.71.6-1.60.2-0.20.2-0.2-0.3-1.00.90.8-0.60.5
Distance moved, locomotor task time 20.91.12.7-1.01.3-1.30.91.4-1.2-1.21.11.0-1.71.7-0.10.1-0.10.10.01.1-1.1-1.0-0.50.6
Vertical activity count, locomotor time 21.21.32.2-0.10.0-0.3-0.30.6-1.0-1.21.20.8-1.01.01.3-1.31.3-1.3-1.21.4-1.5-1.5-1.41.5
Light reinforcement 10.20.40.90.2-0.10.4-0.40.5-0.1-0.40.4-0.1-0.90.90.9-0.90.9-0.9-0.90.6-0.6-0.6-0.50.7
Light reinforcement 21.52.14.62.0-1.72.0-1.5-0.72.11.9-2.0-2.10.6-0.6-0.20.2-0.20.20.2-1.81.81.71.1-1.4
Bone: marrow area3.37.211.71.6-0.61.50.3-3.12.83.4-3.3-2.33.2-3.2-2.72.7-2.72.72.3-3.43.43.42.5-2.3
Bone: maximum diameter1.01.94.10.20.5-0.10.7-0.31.01.4-1.4-0.90.3-0.3-2.02.0-2.02.01.8-1.51.61.61.9-1.7
Bone: maximum force3.15.412.4-1.72.4-1.92.8-0.2-0.21.0-1.10.60.3-0.3-3.53.5-3.53.53.4-1.71.82.03.3-3.1
Bone: maximum moment2.84.811.0-1.62.2-1.82.6-0.2-0.21.0-1.00.70.2-0.2-3.33.3-3.33.33.2-1.51.71.83.1-2.9
Mean time between licks in bursts1.01.44.2-1.70.9-1.30.70.6-1.9-1.71.82.0-0.50.50.8-0.80.8-0.8-0.81.4-1.4-1.3-0.50.7
Mean num. licks in bursts0.30.41.0-0.0-0.20.1-0.30.1-0.3-0.50.50.3-0.20.20.9-0.90.9-0.9-0.90.7-0.7-0.8-0.91.0
Cd content in liver0.60.72.71.4-0.70.9-0.8-0.21.41.2-1.2-1.60.5-0.5-0.20.2-0.20.2-0.3-0.70.70.6-0.10.1
Co content in liver3.03.58.90.5-0.90.6-1.50.8-0.6-1.41.50.2-0.40.42.7-2.72.7-2.7-3.01.8-1.9-2.0-2.72.7
Cu content in liver0.20.30.9-0.50.4-0.50.10.9-0.6-0.60.50.5-0.90.90.1-0.10.1-0.1-0.40.6-0.6-0.6-0.20.3
Fe content in liver0.40.41.1-0.20.6-0.20.7-0.00.40.6-0.6-0.4-0.00.0-1.11.1-1.11.11.0-0.50.50.50.6-0.3
K content in liver1.81.84.2-1.31.8-1.22.1-0.4-0.40.5-0.50.80.3-0.3-1.91.9-1.91.92.0-0.80.91.01.6-1.6
Mg content in liver1.21.22.9-0.20.6-0.00.9-0.90.41.1-1.1-0.10.9-0.9-1.31.3-1.31.31.2-1.31.31.31.7-1.7
Mn content in liver0.91.02.0-1.11.4-1.11.21.2-0.6-0.20.20.6-1.31.3-1.21.2-1.21.21.1-0.00.10.11.1-1.2
Na content in liver0.50.51.4-0.81.2-0.81.10.5-0.3-0.10.10.4-0.40.4-0.80.8-0.80.81.0-0.20.30.31.1-1.0
Rb content in liver0.81.02.81.3-1.01.4-0.6-1.71.31.3-1.3-1.11.4-1.40.1-0.10.1-0.10.1-1.01.00.90.00.1
Se content in liver0.70.81.90.8-0.50.6-0.40.31.01.0-1.1-1.2-0.20.2-0.90.9-0.90.90.9-1.11.11.11.2-1.4
Sr content in liver1.81.64.1-1.71.3-1.60.82.0-1.8-1.51.51.6-2.02.00.1-0.10.1-0.1-0.11.2-1.1-1.00.4-0.4
Zn content in liver0.60.72.2-1.00.8-0.90.71.0-1.0-0.50.51.1-1.01.0-0.60.6-0.60.60.50.1-0.00.01.5-1.3
Bone: minimum diameter2.85.39.11.5-0.51.40.2-2.52.42.8-2.8-1.92.6-2.6-2.22.2-2.22.21.9-3.03.03.02.6-2.5
Time in familiar zone, hab. session 10.10.10.40.3-0.20.3-0.0-0.50.20.3-0.2-0.00.6-0.60.1-0.10.1-0.10.1-0.40.40.40.4-0.6
Time in novel zone, hab. session 10.20.20.80.1-0.40.2-0.4-0.40.1-0.00.0-0.10.4-0.40.3-0.30.3-0.3-0.60.3-0.3-0.3-0.80.9
Total zone transitions, hab. session 10.20.31.7-0.61.3-0.91.10.4-0.5-0.20.20.5-0.30.3-0.60.6-0.60.60.40.2-0.2-0.10.2-0.0
Total locomotion distance, hab. session 10.81.12.10.80.20.60.4-1.41.11.3-1.3-0.81.5-1.5-0.80.8-0.80.80.7-1.31.31.30.8-1.1
Locomotion velocity, hab. session 10.30.40.70.40.60.10.6-0.70.50.7-0.7-0.30.8-0.8-0.60.6-0.60.60.5-0.80.80.80.5-0.9
Time in familiar zone, hab. session 20.90.91.9-0.80.3-0.60.20.2-1.0-1.21.21.1-0.10.11.0-1.01.0-1.0-0.91.2-1.3-1.2-1.31.4
Time in novel zone, hab. session 20.60.61.90.3-0.10.20.0-0.10.50.8-0.8-0.50.2-0.2-0.90.9-0.90.90.6-0.91.01.01.3-1.4
Total zone transitions, hab. session 21.01.23.3-1.01.6-1.31.8-0.5-0.60.1-0.11.00.4-0.4-1.51.5-1.51.51.6-0.40.50.61.3-1.2
Total locomotion distance, hab. session 20.81.02.30.10.8-0.21.1-1.40.40.9-0.80.11.5-1.5-1.01.0-1.01.01.1-1.11.11.11.1-1.2
Locomotion velocity, hab. session 21.01.32.80.50.50.10.8-1.60.71.2-1.1-0.31.7-1.7-1.11.1-1.11.11.2-1.41.41.41.1-1.3
Novel to familiar place preference ratio0.80.81.9-0.60.3-0.60.40.8-0.20.2-0.30.2-0.90.9-1.41.4-1.41.41.4-0.40.50.51.3-1.2
Novelty place preference0.50.51.2-0.3-0.1-0.20.00.60.10.4-0.4-0.1-0.70.7-1.11.1-1.11.11.1-0.40.50.51.1-1.0
Time in novel zone, NPP test0.50.51.3-0.4-0.1-0.20.00.50.00.4-0.4-0.0-0.60.6-1.11.1-1.11.11.0-0.50.50.51.1-1.1
Total zone transitions, NPP test1.01.44.3-1.52.1-1.82.10.2-0.9-0.30.31.1-0.30.3-1.61.6-1.61.61.60.00.10.20.7-0.6
Total locomotion distance, NPP test0.40.61.30.00.7-0.20.9-1.10.20.6-0.60.11.0-1.0-0.90.9-0.90.91.0-0.70.70.80.5-0.6
Locomotion velocity, NPP test0.20.30.70.10.7-0.30.8-0.80.20.4-0.4-0.00.8-0.8-0.70.7-0.70.70.8-0.50.50.50.2-0.3
Intraocular pressure1.01.45.41.6-2.01.3-2.31.00.6-0.1-0.0-1.2-1.11.11.4-1.41.4-1.4-1.60.4-0.4-0.6-0.70.9
Delta distance traveled before/after self-admin0.20.21.00.0-0.1-0.1-0.30.0-0.2-0.40.50.1-0.00.00.4-0.40.4-0.4-0.60.6-0.6-0.6-1.01.0
Delta ambulatory time before/after self-admin0.30.31.5-0.10.1-0.3-0.0-0.0-0.2-0.50.50.20.3-0.30.4-0.40.4-0.4-0.50.6-0.6-0.6-1.21.2
Parametrial fat weight2.34.59.01.8-1.41.8-0.7-2.72.52.8-2.8-2.13.0-3.0-1.51.5-1.51.51.0-2.62.62.51.8-1.1
Pavlov. Cond. lever latency0.40.52.10.6-0.70.6-0.80.00.30.00.0-0.60.1-0.10.8-0.80.8-0.8-0.90.5-0.5-0.6-1.41.5
Pavlov. Cond. magazine entry latency0.50.72.6-0.40.8-0.50.9-0.1-0.10.4-0.40.30.2-0.2-1.01.0-1.01.01.1-0.70.80.81.6-1.5
Pavlov. Cond. change in total contacts0.40.41.40.4-0.30.3-0.30.20.60.6-0.6-0.6-0.00.0-0.80.8-0.80.80.8-0.80.80.81.1-1.2
Pavlov. Cond. index score0.10.10.6-0.30.5-0.40.40.5-0.3-0.30.30.3-0.40.4-0.20.2-0.20.20.4-0.00.10.10.6-0.7
Pavlov. Cond. latency score0.10.10.7-0.30.5-0.40.50.1-0.2-0.10.10.3-0.10.1-0.30.3-0.30.30.5-0.20.20.20.7-0.9
Pavlov. Cond. lever contacts0.10.10.7-0.30.4-0.30.4-0.2-0.2-0.00.00.40.2-0.2-0.30.3-0.30.30.4-0.30.30.30.6-0.9
Pavlov. Cond. magazine entry number0.20.21.00.2-0.30.4-0.1-1.00.30.4-0.3-0.21.0-1.00.1-0.10.1-0.1-0.2-0.30.20.2-0.40.3
Pavlov. Cond. intertrial magazine entries0.70.92.71.0-1.41.1-1.60.70.3-0.10.0-0.7-0.80.81.2-1.21.2-1.2-1.40.4-0.5-0.6-0.80.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.50.7-0.70.60.6-0.4-0.30.30.4-0.50.5-0.40.4-0.40.40.6-0.00.10.10.8-0.9
Pavlov. Cond. response bias0.10.10.6-0.10.3-0.30.10.5-0.3-0.20.20.3-0.60.6-0.10.1-0.10.10.2-0.00.00.00.7-0.8
Pavlov. Cond. lever latency0.50.72.30.3-0.60.5-0.80.1-0.1-0.30.4-0.00.3-0.31.3-1.31.3-1.3-1.50.7-0.7-0.8-1.41.1
Pavlov. Cond. magazine entry latency1.61.94.3-1.91.9-2.11.71.4-1.7-1.01.01.7-1.81.8-1.11.1-1.11.11.10.8-0.7-0.60.8-0.7
Pavlov. Cond. change in total contacts0.91.23.0-0.50.8-0.80.80.9-0.10.3-0.3-0.0-1.31.3-1.61.6-1.61.61.7-0.50.60.61.5-1.2
Pavlov. Cond. index score1.11.43.0-1.11.3-1.41.30.9-0.7-0.10.10.7-1.41.4-1.71.7-1.71.71.7-0.10.20.31.5-1.3
Pavlov. Cond. latency score1.11.43.3-0.91.2-1.21.30.6-0.50.1-0.20.5-1.21.2-1.81.8-1.81.81.8-0.40.50.51.6-1.4
Pavlov. Cond. lever contacts0.20.30.8-0.40.3-0.50.30.5-0.2-0.20.20.2-0.90.9-0.60.6-0.60.60.80.00.00.10.6-0.3
Pavlov. Cond. magazine entry number2.53.16.22.2-2.42.5-2.2-2.01.81.0-1.0-1.92.3-2.31.7-1.71.7-1.7-1.7-0.70.50.4-1.61.2
Pavlov. Cond. intertrial magazine entries0.40.51.31.1-0.71.0-0.7-0.81.00.7-0.7-1.20.5-0.50.5-0.50.5-0.5-0.4-0.20.20.1-1.00.9
Pavlov. Cond. lever-magazine prob. diff.1.31.62.9-1.41.4-1.61.41.1-0.9-0.30.30.9-1.51.5-1.61.6-1.61.61.70.00.10.21.4-1.2
Pavlov. Cond. response bias0.70.91.9-1.01.0-1.31.01.1-0.8-0.50.50.8-1.41.4-1.11.1-1.11.11.20.2-0.1-0.10.9-0.7
Time in closed arm before self-admin0.30.30.80.30.2-0.20.20.20.60.4-0.5-0.70.3-0.3-0.90.9-0.90.90.7-0.60.60.70.4-0.5
Time in closed arm after self-admin0.10.21.00.2-0.30.3-0.1-0.70.30.1-0.1-0.11.0-1.00.2-0.20.2-0.2-0.1-0.30.30.30.10.1
Time in open arm before self-admin0.91.02.1-0.3-0.40.2-0.3-0.7-0.8-0.80.90.90.1-0.11.4-1.41.4-1.4-1.21.0-1.1-1.1-1.31.4
Time in open arm after self-admin1.01.11.70.1-0.3-0.0-0.61.0-0.8-1.11.10.6-1.21.21.3-1.31.3-1.3-1.21.2-1.3-1.3-1.20.9
Bone: periosteal estimation2.04.26.90.70.30.40.8-1.61.72.3-2.3-1.41.7-1.7-2.52.5-2.52.52.3-2.52.62.62.6-2.5
Bone: periosteal perimeter1.32.24.30.30.50.00.8-0.91.11.6-1.6-0.90.8-0.8-2.12.1-2.12.11.9-1.71.71.81.8-1.6
Bone: post-yield work6.58.916.40.60.60.41.5-2.32.53.2-3.2-2.02.4-2.4-3.93.9-3.93.94.1-3.63.63.73.3-3.0
Progressive ratio test 1 active lever presses1.81.94.92.2-2.12.0-1.8-1.51.91.6-1.6-2.01.3-1.30.6-0.60.6-0.6-0.7-1.11.00.9-0.50.4
Progressive ratio test 1 breakpoint1.61.74.42.1-1.91.8-1.7-1.31.81.4-1.4-1.91.3-1.30.6-0.60.6-0.6-0.6-1.00.90.8-0.60.6
Progressive ratio test 1 inactive lever presses0.40.51.91.2-1.41.0-1.3-0.80.40.4-0.4-0.30.4-0.40.4-0.40.4-0.4-0.7-0.40.40.30.3-0.4
Progressive ratio test 2 active lever presses3.33.67.92.8-2.42.6-2.1-2.02.72.4-2.4-2.71.8-1.80.2-0.20.2-0.2-0.3-2.12.01.90.5-0.5
Progressive ratio test 2 breakpoint3.43.99.53.1-2.93.0-2.7-1.82.82.2-2.2-2.91.7-1.70.9-0.90.9-0.9-1.0-1.81.71.50.10.1
Progressive ratio test 2 inactive lever presses4.75.415.03.9-3.43.4-3.0-2.53.02.8-2.8-3.01.8-1.80.5-0.50.5-0.5-0.8-2.42.32.10.9-1.0
Incentive Sensitization - Responses0.70.71.41.1-0.81.0-0.7-0.71.01.1-1.1-1.00.4-0.4-0.20.2-0.20.20.2-1.11.11.11.2-1.0
Incentive Sensitization - Breakpoint0.90.91.61.3-1.01.2-0.9-0.71.21.2-1.3-1.20.5-0.5-0.00.0-0.00.00.0-1.31.21.21.2-1.0
Sum of active levers in priming session hrs 5-60.80.84.5-0.40.2-0.5-0.12.1-0.5-0.70.60.0-2.12.1-0.00.0-0.00.00.00.7-0.6-0.70.10.1
Progressive ratio1.82.15.7-1.32.1-1.42.3-0.1-0.10.4-0.40.30.0-0.0-2.32.3-2.32.32.4-0.60.70.91.0-1.0
Food seeking constrained by brief footshock0.20.20.7-0.80.4-0.60.40.0-0.7-0.60.60.80.3-0.30.1-0.10.1-0.1-0.20.6-0.6-0.5-0.40.5
Seeking ratio, punishment vs. effort1.62.06.00.8-1.81.1-1.9-0.1-0.3-0.60.70.20.5-0.52.3-2.32.3-2.3-2.50.9-1.0-1.1-1.01.1
Retroperitoneal fat weight2.89.120.04.5-4.14.4-3.3-4.13.93.7-3.7-3.63.4-3.40.2-0.20.2-0.2-0.4-3.12.92.70.8-0.5
Reaction time number correct0.40.61.3-0.70.6-0.70.50.7-1.1-1.01.01.1-1.11.10.3-0.30.3-0.3-0.31.0-0.9-0.9-0.30.5
Reaction time mean minus median1.11.53.4-1.31.8-1.71.71.1-0.4-0.20.10.3-1.21.2-1.71.7-1.71.71.80.1-0.00.10.4-0.3
Reaction time mean minus median AUC0.70.92.2-1.01.4-1.51.21.2-0.7-0.70.60.5-1.31.3-0.80.8-0.80.80.90.7-0.6-0.6-0.30.5
Reaction time num false alarms1.01.32.7-0.2-0.70.3-0.7-0.3-0.8-1.11.10.80.1-0.11.7-1.71.7-1.7-1.51.2-1.2-1.3-1.71.5
Reaction time num false alarms AUC1.01.42.3-0.9-0.1-0.4-0.20.2-1.3-1.41.51.3-0.50.51.3-1.31.3-1.3-1.21.5-1.5-1.5-1.51.5
Reaction time trials correct on left0.40.61.3-0.70.6-0.70.50.7-1.1-1.01.01.1-1.11.10.3-0.30.3-0.3-0.31.0-0.9-0.9-0.30.5
Reaction time trials on left0.50.71.5-0.80.7-0.80.50.8-1.2-1.11.11.1-1.21.20.3-0.30.3-0.3-0.31.1-1.0-1.0-0.30.6
Reaction time mean0.10.20.50.5-0.10.1-0.10.10.60.6-0.6-0.7-0.40.4-0.50.5-0.50.50.6-0.30.30.3-0.2-0.0
Reaction time mean AUC0.20.20.70.6-0.10.1-0.20.10.70.7-0.7-0.8-0.40.4-0.50.5-0.50.50.6-0.40.40.4-0.2-0.0
Median of all reaction times0.20.30.80.9-0.50.5-0.4-0.20.70.8-0.8-0.8-0.10.1-0.30.3-0.30.30.4-0.60.60.50.0-0.3
Reaction time omissions0.50.61.3-0.70.7-1.10.50.9-0.8-0.90.90.7-1.11.1-0.00.0-0.00.00.21.0-1.0-0.9-0.71.0
Reaction time false alarm rate0.40.51.1-0.2-0.60.3-0.5-0.5-0.4-0.50.60.50.5-0.51.1-1.11.1-1.1-0.90.6-0.6-0.7-1.10.9
Reaction time premature initiation rate1.72.37.7-2.62.2-2.31.91.1-2.5-1.91.92.8-0.70.70.1-0.10.1-0.10.11.2-1.1-1.00.8-0.9
Reaction time premature initiations2.94.111.4-3.02.6-2.82.11.9-3.2-2.72.83.4-1.71.70.4-0.40.4-0.4-0.32.0-2.0-1.80.3-0.3
Std. dev. reaction times0.20.31.0-0.30.6-0.60.50.80.0-0.10.0-0.3-1.01.0-0.50.5-0.50.50.70.3-0.3-0.3-0.50.6
Reaction time trials completed0.50.71.5-0.80.7-0.80.50.8-1.2-1.11.11.1-1.21.20.3-0.30.3-0.3-0.31.1-1.0-1.0-0.30.6
Reaction time trials AUC0.30.51.1-0.70.6-0.60.40.5-1.0-0.90.91.0-1.01.00.3-0.30.3-0.3-0.30.9-0.9-0.9-0.30.5
Run reversals in cocaine runway, females0.90.92.0-1.11.0-0.91.3-1.2-0.7-0.10.21.31.0-1.0-1.01.0-1.01.01.1-0.40.50.51.4-1.3
Run reversals in cocaine runway, males0.10.10.70.40.3-0.10.1-0.20.1-0.10.1-0.20.3-0.30.2-0.20.2-0.2-0.20.3-0.3-0.3-0.80.8
Latency to leave start box in cocaine runway0.90.91.90.20.10.50.4-1.11.11.1-1.1-0.91.4-1.4-0.70.7-0.70.71.0-1.31.31.30.9-1.0
Latency to leave start box in cocaine runway, F0.10.10.3-0.10.10.30.2-0.10.40.4-0.4-0.30.3-0.3-0.10.1-0.10.10.5-0.50.50.50.5-0.5
Latency to leave start box in cocaine runway, M0.90.92.40.20.10.30.4-1.31.21.1-1.1-1.11.5-1.5-0.80.8-0.80.80.8-1.01.01.0-0.00.0
Std. dev. time between licks in bursts0.60.71.4-0.6-0.2-0.2-0.2-0.2-0.9-1.01.01.00.3-0.31.1-1.11.1-1.1-1.20.8-0.9-0.9-0.80.8
Total sessions with >9 infusions2.22.47.51.6-1.11.4-0.6-2.71.82.2-2.2-1.52.2-2.2-0.80.8-0.80.80.6-1.81.81.70.4-0.6
Short access day 1 total inactive lever presses2.32.56.12.4-2.52.4-2.1-2.11.81.7-1.7-1.71.7-1.70.7-0.70.7-0.7-0.9-1.51.41.20.4-0.4
Short access day 10 total inactive lever presses1.61.74.31.7-2.11.9-2.0-1.21.10.6-0.5-1.11.5-1.51.5-1.51.5-1.5-1.7-0.30.20.1-0.70.8
Short access day 1 total infusions2.32.47.02.0-1.81.9-1.2-2.61.92.3-2.2-1.51.9-1.9-0.40.4-0.40.40.3-1.71.71.60.4-0.4
Short access day 10 total infusions3.74.110.61.6-1.21.6-0.4-3.32.12.9-2.8-1.62.4-2.4-1.51.5-1.51.51.6-2.52.52.51.3-1.5
Short access total infusions2.22.57.71.4-1.21.4-0.5-2.81.72.3-2.2-1.21.9-1.9-1.01.0-1.01.01.0-1.91.81.80.7-0.7
Short access day 1 locomotion2.32.56.81.5-1.51.5-0.8-2.61.52.1-2.1-1.01.8-1.8-0.80.8-0.80.80.5-2.02.01.91.6-1.7
Short access day 10 total locomotion1.71.93.91.3-1.21.4-0.8-2.01.41.7-1.7-1.01.7-1.7-0.50.5-0.50.50.3-1.81.81.71.6-1.7
Short access total locomotion2.22.35.51.2-1.11.3-0.6-2.31.31.8-1.8-0.81.9-1.9-0.80.8-0.80.80.6-2.02.01.91.9-2.0
One hour access (0.3 mA shock)5.56.415.23.9-3.83.7-3.4-2.83.42.9-2.8-3.42.5-2.50.8-0.80.8-0.8-1.1-2.52.32.10.2-0.4
Compulsive drug intake4.24.39.8-2.31.6-2.01.12.4-2.9-3.13.12.8-1.91.91.1-1.11.1-1.1-1.02.6-2.5-2.5-1.00.9
One hour access (shock baseline)6.57.617.84.2-3.73.7-3.2-2.94.13.6-3.6-4.22.4-2.40.1-0.10.1-0.1-0.5-2.92.82.60.1-0.2
Social response proportion0.40.41.1-0.91.1-1.11.00.7-0.6-0.60.60.6-0.50.5-0.50.5-0.50.50.90.3-0.3-0.20.3-0.0
Social responses0.71.01.7-0.81.0-1.00.80.9-1.1-1.31.31.0-1.31.30.3-0.30.3-0.3-0.01.3-1.2-1.2-0.91.1
Social time0.50.61.0-0.80.9-1.00.70.7-0.9-0.80.90.8-0.80.80.1-0.10.1-0.1-0.01.0-1.0-1.0-1.00.9
Soleus weight1.54.411.63.3-3.03.4-2.8-2.52.61.9-1.8-2.62.1-2.11.5-1.51.5-1.5-1.5-1.31.10.9-1.31.0
Bone: stiffness1.82.97.5-1.32.0-1.62.20.1-0.10.6-0.70.3-0.20.2-2.72.7-2.72.72.7-1.01.11.31.9-1.7
Tibialis anterior weight4.314.837.7-5.86.1-6.15.43.9-4.7-3.13.04.8-4.04.0-3.03.0-3.03.02.92.0-1.8-1.42.1-2.0
Time to tail flick, vehicle, before self-admin1.92.04.6-0.81.1-0.71.4-0.70.31.1-1.1-0.00.9-0.9-1.91.9-1.91.92.0-1.31.41.52.1-1.7
Time to tail flick, vehicle, after self-admin1.92.16.0-2.12.3-2.12.4-0.2-1.0-0.40.41.40.6-0.6-1.91.9-1.91.91.8-0.20.30.41.2-0.9
Time to tail flick, test, before self-admin1.31.23.90.6-0.20.40.2-2.00.61.2-1.1-0.11.7-1.7-0.80.8-0.80.80.5-1.41.31.41.5-1.5
Time to tail flick, test, after self-admin0.10.10.3-0.10.2-0.40.20.2-0.1-0.20.20.1-0.20.2-0.20.2-0.20.20.30.2-0.2-0.2-0.50.5
Delta time to tail flick, vehicle, before/after SA0.50.51.4-1.11.2-1.21.20.2-0.8-0.70.70.90.0-0.0-0.50.5-0.50.50.50.5-0.5-0.4-0.40.3
Delta time to tail flick, test, before/after SA2.21.95.8-0.80.4-0.9-0.12.4-1.1-1.71.60.6-2.12.10.9-0.90.9-0.9-0.61.7-1.7-1.7-1.61.6
Tibia length0.51.53.9-0.60.9-0.90.91.4-0.10.2-0.3-0.0-1.31.3-1.71.7-1.71.71.7-0.60.70.81.8-2.0
Ambulatory time before self-admin0.40.41.30.10.3-0.20.30.50.00.3-0.4-0.1-1.11.1-0.80.8-0.80.80.7-0.30.40.41.1-0.9
Ambulatory time after self-admin0.30.30.80.9-0.50.6-0.6-0.10.70.7-0.7-0.8-0.10.1-0.30.3-0.30.30.2-0.70.70.60.8-0.7
Bone: tissue strength0.10.10.40.3-0.30.3-0.30.20.20.1-0.1-0.3-0.60.6-0.00.0-0.00.00.10.1-0.1-0.1-0.20.4
Total heroin consumption2.63.07.0-2.52.3-2.62.02.2-2.2-1.71.72.1-2.12.1-0.90.9-0.90.90.81.7-1.6-1.4-0.30.4
Bone: trabecular number1.21.94.6-0.30.5-0.40.9-0.40.51.1-1.2-0.30.3-0.3-2.02.0-2.02.02.0-1.41.51.52.1-1.9
Bone: trabecular spacing1.11.43.1-0.0-0.30.2-0.60.4-0.7-1.01.10.6-0.50.51.7-1.71.7-1.7-1.61.3-1.4-1.4-1.61.8
Bone: trabecular thickness0.80.92.01.0-0.91.1-0.6-1.11.31.4-1.4-1.20.7-0.7-0.60.6-0.60.60.6-1.11.11.10.4-0.7
Bone: trabecular tissue density1.62.35.22.3-2.32.3-2.2-1.01.70.8-0.8-2.00.6-0.61.5-1.51.5-1.5-1.2-0.1-0.0-0.2-1.91.9
Water consumed over 24 hours1.11.32.7-1.10.9-1.20.41.6-1.4-1.61.61.2-1.21.20.9-0.90.9-0.9-0.81.4-1.3-1.3-0.60.5
Number of responses in last shaping day0.60.62.11.1-1.50.9-1.4-0.5-0.00.00.00.1-0.40.40.9-0.90.9-0.9-1.20.2-0.3-0.3-0.30.2